Guylaine Hoffner

Identifiants chercheurs

IdHAL :

guylaine-hoffner

ORCID :

0000-0001-7027-7919

Publications

Article dans une revue (18)

Transcranial direct current stimulation modulates primate brain dynamics across states of consciousness Guylaine Hoffner,Pablo Castro,Lynn Uhrig,Camilo Miguel Signorelli,Morgan Dupontet al. eLife, 2025, 13, pp.RP101688. ⟨10.7554/eLife.101688⟩ Article dans une revue hal-05345720v1
Transient brain activity dynamics discriminate levels of consciousness during anesthesia Scott Ensel,Lynn Uhrig,Ayberk Ozkirli,Guylaine Hoffner,Jordy Tasserieet al. Communications Biology, 2024, 7 (1), pp.716. ⟨10.1038/s42003-024-06335-x⟩ Article dans une revue hal-04616713v1
Transglutaminase in neurological disease Guylaine Hoffner,Philippe Djian Oncotarget, 2017, 8 (34), pp.55772-55773. ⟨10.18632/oncotarget.19694⟩ Article dans une revue hal-03036731v1
Identification of brain substrates of transglutaminase by functional proteomics supports its role in neurodegenerative diseases William André,Isabelle Nondier,Maud Valensi,François Guillonneau,Christian Federiciet al. Neurobiology of Disease, 2017, 101, pp.40-58. ⟨10.1016/j.nbd.2017.01.007⟩ Article dans une revue hal-03036725v1
Inclusions of R6/2 Mice Are Not Amyloid and Differ Structurally from Those of Huntington Disease Brain William André,Christophe Sandt,Isabelle Nondier,Philippe Djian,Guylaine Hoffner Analytical Chemistry, 2017, 89 (10), pp.5201-5209. ⟨10.1021/acs.analchem.6b04199⟩ Article dans une revue hal-03036727v1
Polyglutamine Aggregation in Huntington Disease: Does Structure Determine Toxicity? Guylaine Hoffner,Philippe Djian Molecular Neurobiology, 2014, 52 (3), pp.1297-1314. ⟨10.1007/s12035-014-8932-1⟩ Article dans une revue hal-05346893v1
Monomeric, oligomeric and polymeric proteins in Huntington disease and other diseases of polyglutamine expansion Guylaine Hoffner,Philippe Djian Brain Sciences, 2014, 4, pp.91-122. ⟨10.3390/brainsci4010091⟩ Article dans une revue hal-05348617v1
Synchrotron-based infrared spectroscopy brings to light the structure of protein aggregates in neurodegenerative diseases Guylaine Hoffner,William André,Christophe Sandt,Philippe Djian Critical Reviews in Analytical Chemistry, 2014, 33 (4), ⟨10.1515/revac-2014-0016⟩ Article dans une revue hal-05346907v1
Structure of Inclusions of Huntington’s Disease Brain Revealed by Synchrotron Infrared Microspectroscopy: Polymorphism and Relevance to Cytotoxicity William André,Christophe Sandt,Paul Dumas,Philippe Djian,Guylaine Hoffner Analytical Chemistry, 2013, 85 (7), pp.3765-3773. ⟨10.1021/ac400038b⟩ Article dans une revue hal-05348652v1
Transglutaminase-Catalyzed Cross linking in Neurological Disease: from Experimental Evidence to Therapeutic Inhibition. G. Hoffner,W. André,A. Vanhoutteghem,S. Souès,P. Djian CNS Neurol Disord Drug Targets, 2009, epub ahead of print Article dans une revue hal-00423444v1
The end product of transglutaminase crosslinking: simultaneous quantitation of [Nepsilon-(gamma-glutamyl) lysine] and lysine by HPLC-MS3. G. Hoffner,G. van Der Rest,P. M. Dansette,P. Djian Analytical Biochemistry, 2009, 384 (2), pp.296-304. ⟨10.1016/j.ab.2008.09.039⟩ Article dans une revue istex hal-00347891v1
Misfolding of proteins with a polyglutamine expansion is facilitated by proteasomal chaperones. Erwann Rousseau,Rieko Kojima,Guylaine Hoffner,Philippe Djian,Anne Bertolotti Journal of Biological Chemistry, 2008, epub ahead of print. ⟨10.1074/jbc.M806256200⟩ Article dans une revue hal-00347893v1
[N(epsilon)-(gamma-glutamyl) lysine] as a potential biomarker in neurological diseases : New detection method and fragmentation pathways. Guylaine Hoffner,Yannik Hoppilliard,Guillaume van Der Rest,Patrick Dansette,Philippe Djianet al. Journal of Mass Spectrometry, 2008, 43 (4), pp.456-469. ⟨10.1002/jms.1331⟩ Article dans une revue istex hal-00203376v1
Aggregation of expanded huntingtin in the brains of patients with Huntington disease Guylaine Hoffner,Sylvie Souès,Philippe Djian Prion, 2007, 1 (1), pp.26-31 Article dans une revue hal-00152974v1
Purification of neuronal inclusions of patients with Huntington disease reveals a broad range of N-terminal fragments of expanded huntingtin and insoluble polymers Guylaine Hoffner,Marie-Laure Island,Philippe Djian Journal of Neurochemistry, 2005, 95, pp.125-136 Article dans une revue hal-00093080v1
Transglutaminase and diseases of the central nervous system. Guylaine Hoffner,Philippe Djian Frontiers in Bioscience, 2005, 10, pp.3078-3092. ⟨10.2741/1764⟩ Article dans une revue hal-00093084v1
Oligomeric and polymeric aggregates formed by proteins containing expanded polyglutamine S. Iuchi,Guylaine Hoffner,P. Verbeke,P. Djian,H. Green Proceedings of the National Academy of Sciences of the United States of America, 2003, 100 (5), pp.2409-2414. ⟨10.1073/pnas.0437660100⟩ Article dans une revue hal-05348736v1
Protein aggregation in Huntington’s disease Guylaine Hoffner,Philippe Djian Biochimie, 2002, 84 (4), pp.273-278. ⟨10.1016/s0300-9084(02)01398-6⟩ Article dans une revue hal-05348770v1

Autre publication scientifique (1)

Polymorphic and amyloid natures of neuronal inclusions in Huntington’s disease brain revealed by IR microspectroscopy. Guylaine Hoffner Synchrotron Highlights 2013, 2013 Autre publication scientifique hal-05348848v1

Chapitre d'ouvrage (1)

Advances in Enzymology Guylaine Hoffner,Philippe Djian,William André,Amandine Vanhoutteghem TRANSGLUTAMINASE IN EPIDERMIS AND NEUROLOGICAL DISEASE OR WHAT MAKES A GOOD CROSSLINKING SUBSTRATE, 78 (1), Wiley, 2011, Advances in Enzymology - and Related Areas of Molecular Biology, ⟨10.1002/9781118105771.ch3⟩ Chapitre d'ouvrage hal-05348697v1

Thèse (1)

Huntingtine: interaction avec les microtubules, agrégation au cours de la maladie de Huntington. Guylaine Hoffner Sciences du Vivant [q-bio]. Université Paris 7 - Denis Diderot, 2004. Français. ⟨NNT : ⟩ Thèse tel-04516596v1