Hamid Morjani

Présentation

CURRICULUM VITAE

Hamid MORJANI

Date of birth: 23/06/1963hamid.morjani@univ-reims.fr University of Reims Champagne-Ardenne (URCA)

**SUMMARY OF BIOGRAPHY **

Hamid MORJANI (PhD) is Professor of Biochemistry at the Faculty of Pharmacy of URCA. His area of expertise and research is the role of the microenvironment in tumor progression, especially in cell proliferation, migration, invasion, and response to targeted therapies. He is involved also in nanomedicine and improvement of tumor sensitivity to chemotherapies. He is co-editor, associate and guest associate editor for several journals. He is also member of several scientific societies (American Association for Cancer Research, Federation of European Biochemical Societies, European Biophysical Societies' Association, European Association for Cancer Research, International Society of Matrix Biology).

PRESENT POSITION

2012- : Professor, Biochemistry, Faculty of PharmacyResearch Laboratory: Translational Bio-spectroscopy (BioSpecT UR 7506).

PREVIOUS POSITIONS

2007-2012: Assistant Professor, Molecular Biology, Faculty of Pharmacy (URCA).1993-2007: Assistant Professor, Biophysics (URCA), Faculty of Pharmacy (URCA).1992-2003: ATER, Biophysics, Faculty of Pharmacy (URCA).

**ACADEMIC QUALIFICATIONS **

1998: HDR - Mechanisms of multidrug resistance in cancer chemotherapy (URCA).1993: PhD in Biophysics - Characterization of drug-target interactions and study of resistance in living tumor cells: contribution of Raman and fluorescence micro-spectroscopies (URCA).1989: Master's degree- Modulation of anticancer drug accumulation in leukemic cells by multidrug-resistance inhibitors: Confocal fluorescence micro-spectroscopy approach (University of Nancy).

MISSIONS AND COLLECTIVE RESPONSIBILITIES

National council of universities, Pharmacy, section 87.

High council for evaluation of research and higher education.

“France Universités” Open Science national network.

Coalition for advancing Research Assessment (CoARA - France).

Open Science Officer (URCA).

Open Science working group (URCA).

Executive Board of URCA.

Head of the Doctoral School “Biology, Chemistry, and Health” (URCA).

International Relations committee (URCA).

Executive Board of the Faculty of Pharmacy (URCA).

Head of Biochemistry department of the Faculty of Pharmacy (URCA).

MEMBER OF SCIENTIFIC SOCIETIES

American Association for Cancer Research, Federation of European Biochemical Societies, French Society of Biophysics, European Association for Cancer Research, French Society of Biochemistry and Molecular Biology, French Society of Cancer, French Society of Oncologic Pharmacy, French Group of Clinical Oncology Pharmacology, French Society of Extracellular Matrix Biology, International Society of Matrix Biology, French Society for Mineralized Tissue Biology, EXON association, AE2BM association.

PUBLICATIONS (1989-2026)

136: Bimoussa A, N’Ait Ousidi A, Fawzi M, El Mansouri A, Laamari Y, Oubella A, Auhmani A, Fdil A, Morjani H, Robert A, Riah A, Daran JC, Ait Itto M. Potential Anticancer Agents Based on Monoterpenic Skeleton With Mono and Bis‐Isoxazoline Derivatives : Diastereoselective Synthesis, Experimental Study, Evaluation of Biological Activity, and Molecular Docking. J. Heterocycl. Chem. 2026; In Press, Corrected Proof, 1–17, https://doi.org/10.1002/jhet.70158.

135: Florent L, Saby C, Courageot MP, Terryn C, Van Gulick L, Vanmansart J, Slimano F, Morjani H. Age-associated changes in type I collagen promote the invasion of BRAF V600E mutated melanoma cells and their resistance to targeted therapies within three-dimensional matrix models. Biomed Pharmacother. 2025; 190:118351. doi: 10.1016/j.biopha.2025.118351.

134: Al Assaad A, Alaouta C, Desmaële D, Buache E, Fossier E, Van Gulick L, Slimano F, Dukic S, Mura S, Morjani H, Beljebbar A. Raman imaging for monitoring deuterated squalene-gemcitabine nanomedicines in single living breast cancer cells. Int J Pharm. 2024 Dec 25;667(Pt A):124870. doi:10.1016/j.ijpharm.2024.124870.

133: Bimoussa A, Oubella A, Alossaimi MA, Aziz M, Attaullah HM, Ejaz SA, Morjani H, Auhmani A, Robert A, Riahi A, Riadi Y, Ait Itto MY. Novel Bis-1,2,3-triazole-thiazolidinone hybrid as anticancer agents that induce apoptosis and molecular modeling study. Future Med Chem. 2024;16(21):2193-2210. doi:10.1080/17568919.2024.2394019.

132: Bimoussa A, Hachim ME, Khatabi KE, Laamari Y, Oubella A, AlAjmi MF, Auhmani A, Ajana MA, Morjani H, Ait Itto MY. Semicarbazone, thiosemicarbazone tailed isoxazoline-pyrazole: synthesis, DFT, biological and computational assessment. Future Med Chem. 2024;16(20):2073-2086. doi: 10.1080/17568919.2024.2394011.

131: Oubella A, Alossaimi MA, Riadi Y, Bhat MA, Bakheit AH, Taha ML, Auhmani A, Morjani H, Geesi MH, Ait Itto MY. Thiazolidinone-linked-1,2,3-triazoles with (R)-Carvone as new potential anticancer agents. Future Med Chem. 2024;16(14):1449-1464. doi: 10.1080/17568919.2024.2351287.

130: Van Gulick L, Saby C, Mayer C, Fossier E, Jaisson S, Okwieka A, Gillery P, Chenais B, Mimouni V, Morjani H, Beljebbar A. Biochemical and morpho-mechanical properties, and structural organization of rat tail tendon collagen in diet-induced obesity model. Int J Biol Macromol. 2024 Jan;254(Pt 3):127936. doi:10.1016/j.ijbiomac.2023.127936.

129: Fawzi M, Bimoussa A, Laamari Y, Oussidi AN, Oubella A, Ketatni EM, Saadi M, Ammari LE, Morjani H, Ait Itto MY, Auhmani A. New (S)-verbenone-isoxazoline-1,3,4-thiadiazole hybrids: synthesis, anticancer activity and apoptosis-inducing effect. Future Med Chem. 2023 Sep;15(17):1603-1619. doi:10.4155/fmc-2023-0173.

128: Byadi S, Abdoullah B, Fawzi M, Irrou E, Ait Elmachkouri Y, Oubella A, Auhmani A, Morjani H, Labd Taha M, Robert A, Aboulmouhajir A, Ait Itto MY. Discovery of a new Bcl-2 inhibitor through synthesis, anticancer activity, docking and MD simulations. J Biomol Struct Dyn. 2024 May;42(8):4145-4154. doi:10.1080/07391102.2023.2218934.

127: Florent L, Saby C, Slimano F, Morjani H. BRAF V600-Mutated Metastatic Melanoma and Targeted Therapy Resistance: An Update of the Current Knowledge. Cancers (Basel). 2023 May 4;15(9):2607. doi: 10.3390/cancers15092607.

126: Zaiou M, Morjani H. Molecular Links between Cancer and Metabolic Diseases: New Perspectives and Therapeutic Strategies for Cancer Prevention and Treatment by Targeting Nutritional Patterns and Metabolic Alterations. Cancers (Basel). 2023 Feb 20;15(4):1350. doi: 10.3390/cancers15041350.

125: Goffin N, Buache E, Charpentier C, Lehrter V, Morjani H, Gobinet C, Piot O. Trajectory Inference for Unraveling Dynamic Biological Processes from Raman Spectral Data. Anal Chem. 2023 Mar 7;95(9):4395-4403. doi:10.1021/acs.analchem.2c04901.

124: Bimoussa A, Fawzi M, Oubella A, Ejaz SA, Sajjad Bilal M, Labd Taha M, Auhmani A, Morjani H, Robert A, Riahi A, Ait Itto MY. Hybrids of thiazolidinone with 1,2,3-triazole derivatives: design, synthesis, biological evaluation, in silico studies, molecular docking, molecular dynamics simulations, and ADMET profiling. J Biomol Struct Dyn. 2023;41(21):11987-11999. doi:10.1080/07391102.2022.2164357.

123: Oubella A, Taia A, Byadi S, Ait Lahcen M, Bimoussa A, Essaber M, Podlipnik C, Morjani H, Ait Itto MY, Aatif A. Chemical profiling, cytotoxic activities through apoptosis induction in human fibrosarcoma and carcinoma cells, and molecular docking of some 1,2,3-triazole-isoxazoline hybrids using the eugenol as a precursors. J Biomol Struct Dyn. 2023 Apr;41(7):2759-2771. doi:10.1080/07391102.2022.2037466. Epub 2022 Feb 17. PMID: 35174765.

122: Oubella A, Bimoussa A, Byadi S, Laamari Y, Fawzi M, N'ait Ousidi A, Oblak D, Auhmani A, Riahi A, Morjani H, Ait Itto MY. Cytotoxic and apoptotic effects of some (R)-carvone-isoxazoline derivatives on human fibrosarcoma and carcinoma cells: experimental evaluation for cytotoxicity, molecular docking and molecular dynamics studies. J Biomol Struct Dyn. 2023 Mar;41(5):1930-1943. doi :10.1080/07391102.2022.2025903. Epub 2022 Jan 11. PMID: 35014592.

121: Toussaint K, Appert-Collin A, Morjani H, Albrecht C, Sartelet H, Romier-Crouzet B, Maurice P, Duca L, Blaise S, Bennasroune A. Neuraminidase-1: A Sialidase Involved in the Development of Cancers and Metabolic Diseases. Cancers (Basel). 2022 Oct 5;14(19):4868. doi: 10.3390/cancers14194868.

120: El Mansouri AE, Lachhab S, Oubella A, Ahmad M, Neyts J, Jochmans D, Chiu W, Vangeel L, De Jonghe S, Morjani H, Ali MA, Zahouily M, Sanghvi YS, Lazrek HB. Synthesis, characterization, molecular docking, and anticancer activities of new 1,3,4-oxadiazole-5-fluorocytosine hybrid derivatives. J Mol Struct. 2022 Sep 9:134135. doi: 10.1016/j.molstruc.2022.134135.

119: Bimoussa A, Oubella A, Bamou FZ, Khdar ZA, Fawzi M, Laamari Y, Ait Itto MY, Morjani H, Auhmani A. New 1,3,4-thiadiazoles derivatives: synthesis, antiproliferative activity, molecular docking and molecular dynamics. Future Med Chem. 2022 Jun;14(12):881-897. doi: 10.4155/fmc-2022-0016.

118: Fawzi M, Oubella A, El Mansouri AE, Bimoussa A, Ketatni EM, Saadi M, El Ammari L, Ait Itto MY, Morjani H, Auhmani A. Novel Hydrazono-2-Iminothiazolidin-4-Ones Based on a Monoterpenic Skeleton as Potential Antitumor Agents: Synthesis, DFT Studies, in Vitro Cytotoxicity, Apoptosis Inducing Properties and Molecular Docking. Chem Biodivers. 2022 Jul;19(7):e202100836. doi: 10.1002/cbdv.202100836. Epub 2022 Jul 5. PMID:35665594.

117: Oubella A, Byadi S, Bimoussa A, Fawzi M, Auhmani A, Podlipnik C, Morjani H, Riahi A, Robert A, Itto MYA. Novel isoxazoline-linked 1,3,4-thiadiazole hybrids as anticancer agents: Design, synthesis, biological evaluation, molecular docking, and molecular dynamics simulation. Arch Pharm (Weinheim). 2022 Sep;355(9):e2200066. doi: 10.1002/ardp.202200066. Epub 2022 May 20. PMID:35594031.

116: Fawzi M, Oubella A, Bimoussa A, Bamou FZ, Khdar ZA, Auhmani A, Riahi A, Robert A, Morjani H, Itto MYA. Design, synthesis, evaluation of new 3-acetylisoxazolines and their hybrid analogous as anticancer agents: In vitro and in silico analysis. Comput Biol Chem. 2022 Jun;98:107666. doi:10.1016/j.compbiolchem.2022.107666. Epub 2022 Mar 24. PMID: 35381466.

115: Ben Arfi1 K, Schneider C, Bennasroune A, Bouland N, Wolak-Thierry A, Collin G, Le CC, Toussaint K, Hachet C, Lehrter V, Dedieu S, Bouché O, Morjani H, Boulagnon-Rombi C, Aline Appert-Collin. DDR1 expression in colon cancer: roles and prognosis impact. Cancers. 2022, 14(4), 928.

114: Oubella A, Bimoussa A, N'ait Oussidi A, Fawzi M, Auhmani A, Morjani H, Riahi A, Esseffar M, Parish C, Ait Itto MY. New 1,2,3-Triazoles from (R)-Carvone: Synthesis, DFT Mechanistic Study and In Vitro Cytotoxic Evaluation. Molecules. 2022 27(3):769.

113: Van Gulick L, Saby C, Jaisson S, Okwieka A, Gillery P, Dervin E, Morjani H, Beljebbar A. An integrated approach to investigate age-related modifications of morphological, mechanical and structural properties of type I collagen. Acta Biomater. 2022 Jan 1;137:64-78. doi: 10.1016/j.actbio.2022.10.020. Epub 2021 Oct 19. PMID: 34673231.

112: Saby C, Maquoi E, Saltel F, Morjani H. Collagen and Discoidin Domain Receptor 1 Partnership: A Multifaceted Role in the Regulation of Breast Carcinoma Cell Phenotype. Front Cell Dev Biol. 2021 Dec 22;9:808625. doi:10.3389/fcell.2021.808625. PMID: 35004699; PMCID: PMC8727774.

111: Oubella A, El Mansouri AE, Fawzi M, Bimoussa A, Laamari Y, Auhmani A, Morjani H, Robert A, Riahi A, Youssef Ait Itto M. Thiazolidinone-linked1,2,3-triazoles with monoterpenic skeleton as new potential anticancer agents: Design, synthesis and molecular docking studies. Bioorg Chem. 2021 Oct;115:105184. doi:10.1016/j.bioorg.2021.105184. Epub 2021 Jul 20. PMID: 34333421.

110: Laamari Y, Oubella A, Bimoussa A, El Mansouri AE, Ketatni EM, Mentre O, Ait Itto MY, Morjani H, Khouili M, Auhmani A. Design, Hemiysnthesis, crystal structure and anticancer activity of 1, 2, 3-triazoles derivatives of totarol. Bioorg Chem. 2021 Oct;115:105165. doi: 10.1016/j.bioorg.2021.105165. Epub 2021 Jul 14. PMID: 34298240.

109: El Mansouri AE, Oubella A, Dânoun K, Ahmad M, Neyts J, Jochmans D, Snoeck R, Andrei G, Morjani H, Zahouily M, Lazrek HB. Discovery of novel furo[2,3-d]pyrimidin-2-one-1,3,4-oxadiazole hybrid derivatives as dual antiviral and anticancer agents that induce apoptosis. Arch Pharm (Weinheim). 2021 Oct;354(10):e2100146. doi: 10.1002/ardp.202100146. Epub 2021 Jun 15. PMID:34128255.

108: Hadami K, Saby C, Dakka N, Collin G, Attaleb M, Khyatti M, Filali-Maltouf A, Morjani H, El Mzibri M. Degradation of p53 by HPV16-E6 variants isolated from cervical cancer specimens of Moroccan women. Gene. 2021 Jul 30;791:145709. doi:10.1016/j.gene.2021.145709. Epub 2021 May 11. PMID: 33984442.

107: Rammal H, Al Assaad A, Dosio F, Stella B, Maksimenko A, Mura S, Van Gulick L, Callewaert M, Desmaële D, Couvreur P, Morjani H, Beljebbar A. Investigation of squalene-doxorubicin distribution and interactions within single cancer cell using Raman microspectroscopy. Nanomedicine. 2021 Jul;35:102404. doi:10.1016/j.nano.2021.102404. Epub 2021 Apr 29. PMID: 33932593.

106: Hachim ME, Oubella A, Byadi S, Fawzi M, Laamari Y, Bahsis L, Aboulmouhajir A, Morjani H, Podlipnik Č, Auhmani A, Ait Itto MY. Newly synthesized (R)-carvone-derived 1,2,3-triazoles: structural, mechanistic, cytotoxic and molecular docking studies. J Biomol Struct Dyn. 2021 Mar 15:1-14. doi:10.1080/07391102.2021.1894984. Epub ahead of print. PMID: 33719863.

105: Courageot MP, Duca L, Martiny L, Devarenne-Charpentier E, Morjani H, El Btaouri H. Thrombospondin-1 Receptor CD47 Overexpression Contributes to P-Glycoprotein-Mediated Multidrug Resistance Against Doxorubicin in Thyroid Carcinoma FTC-133 Cells. Front Oncol. 2020 Dec 7;10:551228. doi:10.3389/fonc.2020.551228. PMID: 33365267; PMCID: PMC7750475.

104: Girault A, Peretti M, Badaoui M, Hémon A, Morjani H, Ouadid-Ahidouch H. The N and C-termini of SPCA2 regulate differently Kv10.1 function: role in the collagen 1-induced breast cancer cell survival. Am J Cancer Res. 2021 Jan1;11(1):251-263. PMID: 33520372; PMCID: PMC7840723.

103: El Bourakadi K, El Mehdi Mekhzoum M, Saby C, Morjani H, Chakchak H, Merghoub N, A Qaiss, Bouhfid R. Synthesis, characterization and in vitro anticancer activity of thiabendazole-derived 1,2,3-triazole derivatives. New J. Chem., 2020,44, 12099-12106.102: El Mansouri AE, Oubella A, Mehdi A, AitItto MY, Zahouily M, Morjani H, Lazrek HB. Design, synthesis, biological evaluation and molecular docking of new 1,3,4-oxadiazole homonucleosides and their double-headed analogs as antitumor agents. Bioorg Chem. 2021 Mar;108:104558. doi: 10.1016/j.bioorg.2020.104558. Epub 2020 Dec 15. PMID: 33358270.

101: Sarazin T, Collin G, Buache E, Van Gulick L, Charpentier C, Terryn C, Morjani H, Saby C. Type I Collagen Aging Increases Expression and Activation of EGFR and Induces Resistance to Erlotinib in Lung Carcinoma in 3D Matrix Model. Front Oncol. 2020 Sep 10;10:1593. doi: 10.3389/fonc.2020.01593. PMID: 33014812; PMCID: PMC7511549.

100: Ouadid-Ahidouch H, Morjani H, Schnipper J, Girault A, Ahidouch A. Effects of the Tumor Environment on Ion Channels: Implication for Breast Cancer Progression. Rev Physiol Biochem Pharmacol. 2021;181:1-38. doi:10.1007/112_2020_19. PMID: 32761457.

99: El Mansouri AE, Oubella A, Maatallah M, AitItto MY, Zahouily M, Morjani H, Lazrek HB. Design, synthesis, biological evaluation and molecular docking of new uracil analogs-1,2,4-oxadiazole hybrids as potential anticancer agents. Bioorg Med Chem Lett. 2020 Oct 1;30(19):127438. doi: 10.1016/j.bmcl.2020.127438. Epub 2020 Jul 28. PMID: 32736079.

98: Le CC, Bennasroune A, Collin G, Hachet C, Lehrter V, Rioult D, Dedieu S, Morjani H, Appert-Collin A. LRP-1 Promotes Colon Cancer Cell Proliferation in 3D Collagen Matrices by Mediating DDR1 Endocytosis. Front Cell Dev Biol. 2020 Jun 3;8:412. doi: 10.3389/fcell.2020.00412. PMID: 32582700; PMCID: PMC7283560.

97: Le CC, Bennasroune A, Langlois B, Salesse S, Boulagnon-Rombi C, Morjani H, Dedieu S, Appert-Collin A. Functional Interplay Between Collagen Network and Cell Behavior Within Tumor Microenvironment in Colorectal Cancer. Front Oncol. 2020 Apr 30;10:527. doi: 10.3389/fonc.2020.00527. PMID: 32426274; PMCID: PMC7204546.

96: Bitchi MB, Magid AA, Kabran FA, Yao-Kouassi PA, Harakat D, Morjani H, Tonzibo FZ, Voutquenne-Nazabadioko L. Isolation and structure elucidation of cyclopeptide alkaloids from the leaves of Heisteria parvifolia. Phytochemistry. 2019 Nov;167:112081. doi: 10.1016/j.phytochem.2019.112081. Epub 2019 Aug 9. PMID: 31404786.

95: Bechkri S, Alabdul Magid A, Voutquenne-Nazabadioko L, Berrehal D, Kabouche A, Lehbili M, Lakhal H, Abedini A, Gangloff SC, Morjani H, Kabouche Z. Triterpenes from Salvia argentea var. aurasiaca and their antibacterial and cytotoxic activities. Fitoterapia. 2019 Nov;139:104296. doi:10.1016/j.fitote.2019.104296. Epub 2019 Aug 8. PMID: 31401222.

94: Bitchi MB, Magid AA, Yao-Kouassi PA, Kabran FA, Harakat D, Martinez A, Morjani H, Tonzibo FZ, Voutquenne-Nazabadioko L. Triterpene saponins from the roots of Parkia bicolor A. Chev. Fitoterapia. 2019 Sep;137:104264. doi:10.1016/j.fitote.2019.104264. Epub 2019 Jul 9. PMID: 31299275.

93: Saby C, Collin G, Sinane M, Buache E, Van Gulick L, Saltel F, Maquoi E, Morjani H. DDR1 and MT1-MMP Expression Levels Are Determinant for Triggering BIK-Mediated Apoptosis by 3D Type I Collagen Matrix in Invasive Basal-Like Breast Carcinoma Cells. Front Pharmacol. 2019 May 3;10:462. doi:10.3389/fphar.2019.00462. PMID: 31130862; PMCID: PMC6509437.

92: Van Gulick L, Saby C, Morjani H, Beljebbar A. Age-related changes in molecular organization of type I collagen in tendon as probed by polarized SHG and Raman microspectroscopy. Sci Rep. 2019 May 13;9(1):7280. doi:10.1038/s41598-019-43636-2. PMID: 31086263; PMCID: PMC6513820.

91: Peretti M, Badaoui M, Girault A, Van Gulick L, Mabille MP, Tebbakha R, Sevestre H, Morjani H, Ouadid-Ahidouch H. Original association of ion transporters mediates the ECM-induced breast cancer cell survival: Kv10.1-Orai1-SPCA2 partnership. Sci Rep. 2019 Feb 4;9(1):1175. doi:10.1038/s41598-018-37602-7. PMID: 30718673; PMCID: PMC6362254.

90: Badaoui M, Mimsy-Julienne C, Saby C, Van Gulick L, Peretti M, Jeannesson P, Morjani H, Ouadid-Ahidouch H. Collagen type 1 promotes survival of human breast cancer cells by overexpressing Kv10.1 potassium and Orai1 calcium channels through DDR1-dependent pathway. Oncotarget. 2017 Jul 8;9(37):24653-24671. doi:10.18632/oncotarget.19065. PMID: 29872495; PMCID: PMC5973854.

89: Saby C, Rammal H, Magnien K, Buache E, Brassart-Pasco S, Van-Gulick L, Jeannesson P, Maquoi E, Morjani H. Age-related modifications of type I collagen impair DDR1-induced apoptosis in non-invasive breast carcinoma cells. Cell Adh Migr. 2018;12(4):335-347. doi: 10.1080/19336918.2018.1472182. Epub 2018 Jun 28. PMID: 29733741; PMCID: PMC6363044.

88: Lehbili M, Alabdul Magid A, Kabouche A, Voutquenne-Nazabadioko L, Morjani H, Harakat D, Kabouche Z. Triterpenoid saponins from Scabiosa stellata collected in North-eastern Algeria. Phytochemistry. 2018 Jun;150:40-49. doi:10.1016/j.phytochem.2018.03.005. Epub 2018 Mar 13. PMID: 29547709.

87: Lehbili M, Alabdul Magid A, Hubert J, Kabouche A, Voutquenne-Nazabadioko L, Renault JH, Nuzillard JM, Morjani H, Abedini A, Gangloff SC, Kabouche Z. Two new bis-iridoids isolated from Scabiosa stellata and their antibacterial, antioxidant, anti-tyrosinase and cytotoxic activities. Fitoterapia. 2018 Mar;125:41-48. doi: 10.1016/j.fitote.2017.12.018. Epub 2017 Dec 19. PMID:29273413.

86: Cherchar H, Lehbili M, Berrehal D, Morjani H, Alabdul Magid A, Voutquenne-Nazabadioko L, Kabouche A, Kabouche Z. A new 2-alkylhydroquinone glucoside from Phagnalon saxatile (L.) Cass. Nat Prod Res. 2018 May;32(9):1010-1016. doi:10.1080/14786419.2017.1375918. Epub 2017 Sep 25. PMID: 28942671.

85: Lehbili M, Alabdul Magid A, Kabouche A, Voutquenne-Nazabadioko L, Abedini A, Morjani H, Gangloff SC, Kabouche Z. Antibacterial, antioxidant and cytotoxic activities of triterpenes and flavonoids from the aerial parts of Salvia barrelieri Etl. Nat Prod Res. 2018 Nov;32(22):2683-2691. doi: 10.1080/14786419.2017.1378207. Epub 2017 Sep 19. PMID: 28925304.

84: Lehbili M, Alabdul Magid A, Kabouche A, Voutquenne-Nazabadioko L, Abedini A, Morjani H, Sarazin T, Gangloff SC, Kabouche Z. Oleanane-type triterpene saponins from Calendula stellata. Phytochemistry. 2017 Dec;144:33-42. doi:10.1016/j.phytochem.2017.08.015. Epub 2017 Sep 4. PMID: 28881197.

83: Mohsen A, Collery P, Garnotel R, Brassart B, Etique N, Mohamed Sabry G, Elsherif Hassan R, Jeannesson P, Desmaële D, Morjani H. A new gallium complex inhibits tumor cell invasion and matrix metalloproteinase MMP-14 expression and activity. Metallomics. 2017 Aug 16;9(8):1176-1184. doi: 10.1039/c7mt00049a. PMID: 28765844.

82: Vatsa-Portugal P, Aziz A, Rondeau M, Villaume S, Morjani H, Clément C, Ait Barka E. How Streptomyces anulatus Primes Grapevine Defenses to Cope with Gray Mold: A Study of the Early Responses of Cell Suspensions. Front Plant Sci. 2017 Jun 28;8:1043. doi: 10.3389/fpls.2017.01043. PMID: 28702033; PMCID: PMC5487444.

81: Benmerache A, Alabdul Magid A, Labed A, Kabouche A, Voutquenne-Nazabadioko L, Hubert J, Morjani H, Kabouche Z. Isolation and characterisation of cytotoxic compounds from Euphorbia clementei Boiss. Nat Prod Res. 2017 Sep;31(18):2091-2098. doi: 10.1080/14786419.2016.1277345. Epub 2017 Jan 9. PMID:28068859.

80: Merghoub N, El Btaouri H, Benbacer L, Gmouh S, Trentesaux C, Brassart B, Attaleb M, Madoulet C, Wenner T, Amzazi S, Morjani H, El Mzibri M. Tomentosin Induces Telomere Shortening and Caspase-Dependant Apoptosis in Cervical Cancer Cells. J Cell Biochem. 2017 Jul;118(7):1689-1698. doi: 10.1002/jcb.25826. Epub 2016 Dec 20. PMID: 27922187.

79: Gossan DP, Alabdul Magid A, Yao-Kouassi PA, Ahibo Coffy A, Josse J, Gangloff SC, Morjani H, Voutquenne-Nazabadioko L. Triterpene glycosides from the aerial parts of Gouania longipetala. Phytochemistry. 2017 Feb;134:71-77. doi:10.1016/j.phytochem.2016.11.004. Epub 2016 Nov 16. PMID: 27865442.

78: Rammal H, Saby C, Magnien K, Van-Gulick L, Garnotel R, Buache E, El Btaouri H, Jeannesson P, Morjani H. Corrigendum: Discoidin Domain Receptors: Potential Actors and Targets in Cancer. Front Pharmacol. 2016 Sep 30;7:346. doi:10.3389/fphar.2016.00346. Erratum for: Front Pharmacol. 2016 Mar 14;7:55. PMID:27703433; PMCID: PMC5043063.

77: Mohsen A, Saby C, Collery P, Sabry GM, Hassan RE, Badawi A, Jeannesson P, Desmaële D, Morjani H. Biological study of the effect of water soluble [N-(2-hydroxybenzyl)-L-aspartato] gallium complexes on breast carcinoma and fibrosarcoma cells. J Biol Inorg Chem. 2016 Oct;21(7):837-49. doi:10.1007/s00775-016-1382-7. Epub 2016 Aug 2. PMID: 27484500.

76: Appert-Collin A, Bennasroune A, Jeannesson P, Terryn C, Fuhrmann G, Morjani H, Dedieu S. Role of LRP-1 in cancer cell migration in 3-dimensional collagen matrix. Cell Adh Migr. 2017 Jul 4;11(4):316-326. doi:10.1080/19336918.2016.1215788. Epub 2016 Jul 27. PMID: 27463962; PMCID:PMC5569966.

75: Saby C, Buache E, Brassart-Pasco S, El Btaouri H, Courageot MP, Van Gulick L, Garnotel R, Jeannesson P, Morjani H. Type I collagen aging impairs discoidin domain receptor 2-mediated tumor cell growth suppression. Oncotarget. 2016 May 3;7(18):24908-27. doi: 10.18632/oncotarget.8795. PMID: 27121132; PMCID:PMC5041879.

74: Rammal H, Saby C, Magnien K, Van-Gulick L, Garnotel R, Buache E, El Btaouri H, Jeannesson P, Morjani H. Discoidin Domain Receptors: Potential Actors and Targets in Cancer. Front Pharmacol. 2016 Mar 14;7:55. doi:10.3389/fphar.2016.00055. Erratum in: Front Pharmacol. 2016 Sep 30;7:346. PMID:27014069; PMCID: PMC4789497.

73: Medves S, Auchter M, Chambeau L, Gazzo S, Poncet D, Grangier B, Verney A, Moussay E, Ammerlaan W, Brisou G, Morjani H, Géli V, Palissot V, Berchem G, Salles G, Wenner T. A high rate of telomeric sister chromatid exchange occurs in chronic lymphocytic leukaemia B-cells. Br J Haematol. 2016 Jul;174(1):57-70. doi: 10.1111/bjh.13995. Epub 2016 Mar 11. PMID: 26970083.

72: Gossan DP, Alabdul Magid A, Yao-Kouassi PA, Josse J, Gangloff SC, Morjani H, Voutquenne-Nazabadioko L. Antibacterial and cytotoxic triterpenoids from the roots of Combretum racemosum. Fitoterapia. 2016 Apr;110:89-95. doi:10.1016/j.fitote.2016.03.002. Epub 2016 Mar 2. PMID: 26946378.

71: Merghoub N, El Btaouri H, Benbacer L, Gmouh S, Trentesaux C, Brassart B, Terryn C, Attaleb M, Madoulet C, Benjouad A, Amzazi S, El Mzibri M, Morjani H. Inula Viscosa Extracts Induces Telomere Shortening and Apoptosis in Cancer Cells and Overcome Drug Resistance. Nutr Cancer. 2016;68(1):131-43. doi:10.1080/01635581.2016.1115105. Epub 2016 Jan 15. PMID: 26771897.

70: Gatouillat G, Magid AA, Bertin E, El btaouri H, Morjani H, Lavaud C, Madoulet C. Medicarpin and millepurpan, two flavonoids isolated from Medicago sativa, induce apoptosis and overcome multidrug resistance in leukemia P388 cells. Phytomedicine. 2015 Dec 1;22(13):1186-94. doi:10.1016/j.phymed.2015.09.005. Epub 2015 Oct 24. PMID: 26598918.

69: Alabdul Magid A, Morjani H, Harakat D, Madoulet C, Dumontet V, Lavaud C. Triterpenoid glycosides from the leaves of Meliosma henryi. Phytochemistry. 2015 Jan;109:49-56. doi: 10.1016/j.phytochem.2014.10.035. Epub 2014 Nov 18. PMID:25468712.

68: Gatouillat G, Magid AA, Bertin E, Okiemy-Akeli MG, Morjani H, Lavaud C, Madoulet C. Cytotoxicity and apoptosis induced by alfalfa (Medicago sativa) leaf extracts in sensitive and multidrug-resistant tumor cells. Nutr Cancer. 2014;66(3):483-91. doi: 10.1080/01635581.2014.884228. Epub 2014 Mar 14. PMID:24628411.

67: Said G, Guilbert M, Morjani H, Garnotel R, Jeannesson P, El Btaouri H. Extracellular matrix proteins modulate antimigratory and apoptotic effects of Doxorubicin. Chemother Res Pract. 2012;2012:268681. doi: 10.1155/2012/268681. Epub 2012 Jul 1. PMID: 22811904; PMCID: PMC3395309.

66: Winckler P, Cailler A, Deturche R, Jeannesson P, Morjani H, Jaffiol R. Microfluidity mapping using fluorescence correlation spectroscopy: a new way to investigate plasma membrane microorganization of living cells. Biochim Biophys Acta. 2012 Nov;1818(11):2477-85. doi: 10.1016/j.bbamem.2012.05.018. Epub 2012 May 26. PMID: 22640696.

65: Merghoub N, Benbacer L, El Btaouri H, Ait Benhassou H, Terryn C, Attaleb M, Madoulet C, Benjouad A, El Mzibri M, Morjani H, Amzazi S. In vitro antiproliferative effect and induction of apoptosis by Retama monosperma L. extract in human cervical cancer cells. Cell Mol Biol (Noisy-le-grand). 2011 Oct 15;57 Suppl:OL1581-91. doi: 10.5772/30025. PMID: 22000488.

64: Eddabra L, Wenner T, El Btaouri H, Baranek T, Madoulet C, Cornillet-Lefebvre P, Morjani H. Arginine 482 to glycine mutation in ABCG2/BCRP increases etoposide transport and resistance to the drug in HEK-293 cells. Oncol Rep. 2012 Jan;27(1):232-7. doi: 10.3892/or.2011.1468. Epub 2011 Sep 20. PMID: 21935580.

63: El Btaouri H, Morjani H, Greffe Y, Charpentier E, Martiny L. Role of JNK/ATF-2 pathway in inhibition of thrombospondin-1 (TSP-1) expression and apoptosis mediated by doxorubicin and camptothecin in FTC-133 cells. Biochim Biophys Acta. 2011 May;1813(5):695-703. doi: 10.1016/j.bbamcr.2011.02.004. Epub 2011 Feb 17. PMID: 21333695.

62: Aouali N, El Btaouri H, Dumontet C, Eddabra L, Malagarie-Cazenave S, Madoulet C, Morjani H. Accumulation of lactosylceramide and overexpression of a PSC833-resistant P-glycoprotein in multidrug-resistant human sarcoma cells. Oncol Rep. 2011 Apr;25(4):1161-7. doi: 10.3892/or.2011.1180. Epub 2011 Feb 10. PMID: 21318225.

61: Gatouillat G, Balasse E, Joseph-Pietras D, Morjani H, Madoulet C. Resveratrol induces cell-cycle disruption and apoptosis in chemoresistant B16 melanoma. J Cell Biochem. 2010 Jul 1;110(4):893-902. doi: 10.1002/jcb.22601. PMID: 20564188.

60: Morjani H, Madoulet C. Immunosuppressors as multidrug resistance reversal agents. Methods Mol Biol. 2010;596:433-46. doi: 10.1007/978-1-60761-416-6_19. PMID: 19949935.

59: Abdeljebbar LH, Benjouad A, Morjani H, Merghoub N, El Haddar S, Humam M, Christen P, Hostettmann K, Bekkouche K, Amzazi S. Antiproliferative effects of withanolides from Withania adpressa. Therapie. 2009 Mar-Apr;64(2):121-7. doi:10.2515/therapie/2009015. Epub 2009 Aug 11. PMID: 19664406.

58: Tang R, Cohen S, Perrot JY, Faussat AM, Zuany-Amorim C, Marjanovic Z, Morjani H, Fava F, Corre E, Legrand O, Marie JP. P-gp activity is a critical resistance factor against AVE9633 and DM4 cytotoxicity in leukaemia cell lines, but not a major mechanism of chemoresistance in cells from acute myeloid leukaemia patients. BMC Cancer. 2009 Jun 23;9:199. doi: 10.1186/1471-2407-9-199. PMID: 19549303; PMCID: PMC2708190.

57: Rath G, Schneider C, Langlois B, Sartelet H, Morjani H, Btaouri HE, Dedieu S, Martiny L. De novo ceramide synthesis is responsible for the anti-tumor properties of camptothecin and doxorubicin in follicular thyroid carcinoma. Int J Biochem Cell Biol. 2009 May;41(5):1165-72. doi: 10.1016/j.biocel.2008.10.021. Epub 2008 Nov 5. PMID: 19027085.

56: Guittat L, Alberti P, Gomez D, De Cian A, Pennarun G, Lemarteleur T, Belmokhtar C, Paterski R, Morjani H, Trentesaux C, Mandine E, Boussin F, Mailliet P, Lacroix L, Riou JF, Mergny JL. Targeting human telomerase for cancer therapeutics. Cytotechnology. 2004 Jun;45(1-2):75-90. doi:10.1007/s10616-004-5127-z. PMID: 19003245; PMCID: PMC3449961.

55: Tang R, Faussat AM, Perrot JY, Marjanovic Z, Cohen S, Storme T, Morjani H, Legrand O, Marie JP. Zosuquidar restores drug sensitivity in P-glycoprotein expressing acute myeloid leukemia (AML). BMC Cancer. 2008 Feb 13;8:51. doi:10.1186/1471-2407-8-51. PMID: 18271955; PMCID: PMC2258302.

54: Gunaratnam M, Greciano O, Martins C, Reszka AP, Schultes CM, Morjani H, Riou JF, Neidle S. Mechanism of acridine-based telomerase inhibition and telomere shortening. Biochem Pharmacol. 2007 Sep 1;74(5):679-89. doi:10.1016/j.bcp.2007.06.011. Epub 2007 Jun 16. PMID: 17631279.

53: Gomez D, Wenner T, Brassart B, Douarre C, O'Donohue MF, El Khoury V, Shin-Ya K, Morjani H, Trentesaux C, Riou JF. Telomestatin-induced telomere uncapping is modulated by POT1 through G-overhang extension in HT1080 human tumor cells. J Biol Chem. 2006 Dec 15;281(50):38721-9. doi: 10.1074/jbc.M605828200. Epub 2006 Oct 17. PMID: 17050546.

52: Rath GM, Schneider C, Dedieu S, Sartelet H, Morjani H, Martiny L, El Btaouri H. Thrombospondin-1 C-terminal-derived peptide protects thyroid cells from ceramide-induced apoptosis through the adenylyl cyclase pathway. Int J Biochem Cell Biol. 2006;38(12):2219-28. doi: 10.1016/j.biocel.2006.07.004. Epub 2006 Aug 12. PMID: 16971166.

51: Rath GM, Schneider C, Dedieu S, Rothhut B, Soula-Rothhut M, Ghoneim C, Sid B, Morjani H, El Btaouri H, Martiny L. The C-terminal CD47/IAP-binding domain of thrombospondin-1 prevents camptothecin- and doxorubicin-induced apoptosis in human thyroid carcinoma cells. Biochim Biophys Acta. 2006 Oct;1763(10):1125-34. doi: 10.1016/j.bbamcr.2006.08.001. Epub 2006 Aug 5. PMID: 16962673.

50: Riou JF, Morjani H, Trentesaux C. Télomères et télomérase, de nouvelles cibles pour la chimiothérapie anticancéreuse [Telomeres and telomerase, new targets for anticancer chemotherapy]. Ann Pharm Fr. 2006 Mar;64(2):97-105. French. doi: 10.1016/s0003-4509(06)75301-9. PMID: 16568010.

49: El Btaouri H, Rath G, Morjani H, Schneider C, Petitfrere E, Antonicelli F, Martiny L. Interleukin-1beta-induced apoptosis through adenylyl cyclase and ERK1/2 inhibition in primary cultured thyroid cells. Biochem Biophys Res Commun. 2006 Jan 13;339(2):469-76. doi: 10.1016/j.bbrc.2005.10.213. Epub 2005 Nov 15. PMID: 16310170.

48: Bonhoure E, Pchejetski D, Aouali N, Morjani H, Levade T, Kohama T, Cuvillier O. Overcoming MDR-associated chemoresistance in HL-60 acute myeloid leukemia cells by targeting sphingosine kinase-1. Leukemia. 2006 Jan;20(1):95-102. doi:10.1038/sj.leu.2404023. PMID: 16281067.

47: Benderra Z, Faussat AM, Sayada L, Perrot JY, Tang R, Chaoui D, Morjani H, Marzac C, Marie JP, Legrand O. MRP3, BCRP, and P-glycoprotein activities are prognostic factors in adult acute myeloid leukemia. Clin Cancer Res. 2005 Nov 1;11(21):7764-72. doi: 10.1158/1078-0432.CCR-04-1895. PMID: 16278398.

46: Abdellaoui K, Boustta M, Vert M, Morjani H, Manfait M. Metabolite-derived artificial polymers designed for drug targeting, cell penetration and bioresorption. Eur J Pharm Sci. 1998 Jan;6(1):61-73. doi: 10.1016/s0928-0987(97)00069-9. PMID: 16256709.

45: Barbier M, Morjani H, Muirhead KA, Ronot X, Boutonnat J. Optimization of PKH67 labeling conditions for proliferation monitoring in daunorubicin-treated leukemic cells. Oncol Rep. 2005 Aug;14(2):553-9. doi: 10.3892/or.14.2.553. PMID:16012744.

44: Aouali N, Eddabra L, Macadré J, Morjani H. Immunosuppressors and reversion of multidrug-resistance. Crit Rev Oncol Hematol. 2005 Oct;56(1):61-70. doi:10.1016/j.critrevonc.2004.12.010. PMID: 15978826.

43: Douarre C, Gomez D, Morjani H, Zahm JM, O'donohue MF, Eddabra L, Mailliet P, Riou JF, Trentesaux C. Overexpression of Bcl-2 is associated with apoptotic resistance to the G-quadruplex ligand 12459 but is not sufficient to confer resistance to long-term senescence. Nucleic Acids Res. 2005 Apr 14;33(7):2192-203. doi: 10.1093/nar/gki514. PMID: 15831792; PMCID: PMC1079972.

42: Riou JF, Gomez D, Mergny JL, Guittat L, Paterski R, Chenais B, Morjani H, Trentesaux C. Régulation de la longueur des télomères: rendre le télomère accessible? [Regulation of telomeres length: making the telomeres accessible?]. Bull Cancer. 2005 Jan;92(1):13-22. French. PMID: 15811846.

41: Palissot V, Morjani H, Belloc F, Cotteret S, Dufer J, Berchem G. From molecular characteristics to cellular events in apoptosis-resistant HL-60 cells. Int J Oncol. 2005 Mar;26(3):825-34. PMID: 15703842.

40: Gomez D, Aouali N, Renaud A, Douarre C, Shin-Ya K, Tazi J, Martinez S, Trentesaux C, Morjani H, Riou JF. Resistance to senescence induction and telomere shortening by a G-quadruplex ligand inhibitor of telomerase. Cancer Res. 2003 Oct 1;63(19):6149-53. PMID: 14559794.

39: Gomez D, Aouali N, Londoño-Vallejo A, Lacroix L, Mégnin-Chanet F, Lemarteleur T, Douarre C, Shin-ya K, Mailliet P, Trentesaux C, Morjani H, Mergny JL, Riou JF. Resistance to the short term antiproliferative activity of the G-quadruplex ligand 12459 is associated with telomerase overexpression and telomere capping alteration. J Biol Chem. 2003 Dec 12;278(50):50554-62. doi:10.1074/jbc.M308440200. Epub 2003 Oct 2. PMID: 14525974.

38: Aouali N, Morjani H, Trussardi A, Soma E, Giroux B, Manfait M. Enhanced cytotoxicity and nuclear accumulation of doxorubicin-loaded nanospheres in human breast cancer MCF7 cells expressing MRP1. Int J Oncol. 2003 Oct;23(4):1195-201. PMID: 12964004.

37: Richard D, Morjani H, Chénais B. Free radical production and labile iron pool decrease triggered by subtoxic concentration of aclarubicin in human leukemia cell lines. Leuk Res. 2002 Oct;26(10):927-31. doi:10.1016/s0145-2126(02)00030-9. PMID: 12163054.

36: Chauvier D, Kegelaer G, Morjani H, Manfait M. Reversal of multidrug resistance-associated protein-mediated daunorubicin resistance by camptothecin. J Pharm Sci. 2002 Aug;91(8):1765-75. doi: 10.1002/jps.10162. PMID: 12115804.

35: Chauvier D, Morjani H, Manfait M. Homocamptothecin-daunorubicin association overcomes multidrug-resistance in breast cancer MCF7 cells. Breast Cancer Res Treat. 2002 May;73(2):113-25. doi: 10.1023/a:1015244604336. PMID: 12088114.

34: Chénais B, Morjani H, Drapier JC. Impact of endogenous nitric oxide on microglial cell energy metabolism and labile iron pool. J Neurochem. 2002 May;81(3):615-23. doi: 10.1046/j.1471-4159.2002.00864.x. PMID: 12065670; PMCID:PMC2816204.

33: Chauvier D, Morjani H, Manfait M. Ceramide involvement in homocamptothecin-and camptothecin-induced cytotoxicity and apoptosis in colon HT29 cells. Int J Oncol. 2002 Apr;20(4):855-63. PMID: 11894136.

32: Morjani H, Aouali N, Belhoussine R, Veldman RJ, Levade T, Manfait M. Elevation of glucosylceramide in multidrug-resistant cancer cells and accumulation in cytoplasmic droplets. Int J Cancer. 2001 Oct 15;94(2):157-65. doi: 10.1002/ijc.1449. PMID: 11668492.

31: Benderra Z, Trussardi A, Morjani H, Villa AM, Doglia SM, Manfait M. Regulation of cellular glutathione modulates nuclear accumulation of daunorubicin in human MCF7 cells overexpressing multidrug resistance associated protein. Eur J Cancer. 2000 Feb;36(3):428-34. doi:10.1016/s0959-8049(99)00288-9. PMID: 10708946.

30: Belhoussine R, Morjani H, Gillet R, Palissot V, Manfait M. Two distinct modes of oncoprotein expression during apoptosis resistance in vincristine and daunorubicin multidrug-resistant HL60 cells. Adv Exp Med Biol. 1999;457:365-81. doi: 10.1007/978-1-4615-4811-9_39. PMID: 10500812.

29: Benderra Z, Morjani H, Trussardi A, Manfait M. Evidence for functional discrimination between leukemic cells overexpressing multidrug-resistance associated protein and P-glycoprotein. Adv Exp Med Biol. 1999;457:151-60. doi10.1007/978-1-4615-4811-9_17. PMID: 10500790.

28: Belhoussine R, Morjani H, Sharonov S, Ploton D, Manfait M. Characterization of intracellular pH gradients in human multidrug-resistant tumor cells by means of scanning microspectrofluorometry and dual-emission-ratio probes. Int J Cancer. 1999 Mar 31;81(1):81-9. PMID: 10077157.

27: Morjani H, Belhoussine R, Lahlil R, Manfait M. Pirarubicin nuclear uptake does not correlate with its induced cell death effect during reversal of multidrug resistance by quinine in human K562 and CEM leukemic cells. Eur J Haematol. 1998 Oct;61(4):240-9. doi: 10.1111/j.1600-0609.1998.tb01709.x. PMID:9820630.

26: Belhoussine R, Morjani H, Millot JM, Sharonov S, Manfait M. Confocal scanning microspectrofluorometry reveals specific anthracyline accumulation in cytoplasmic organelles of multidrug-resistant cancer cells. J Histochem Cytochem. 1998 Dec;46(12):1369-76. doi: 10.1177/002215549804601205. PMID:9815278.

25: Sockalingum GD, Beljebbar A, Morjani H, Angiboust JF, Manfait M. Characterization of island films as surface-enhanced Raman spectroscopy substrates for detecting low antitumor drug concentrations at single cell level. Biospectroscopy. 1998;4(5 Suppl):S71-8. PMID: 9787916.

24: Morjani H, Beljebbar A, Sockalingum GD, Mattioli TA, Bonnier D, Gronemeyer H, Manfait M. Surface-enhanced Raman scattering and fluorescence spectroscopy reveal molecular interactions of all-trans retinoic acid and RAR gamma ligand-binding domain. Biospectroscopy. 1998;4(5):297-302. PMID: 9787905.

23: Benderra Z, Morjani H, Trussardi A, Manfait M. Characterization of H+-ATPase-dependent activity of multidrug resistance-associated protein in homoharringtonine-resistant human leukemic K562 cells. Leukemia. 1998 Oct;12(10):1539-44. doi: 10.1038/sj.leu.2401166. PMID: 9766497.

22: Abdellaoui K, Boustta M, Morjani H, Manfait M, Vert M. Uptake and intracellular distribution of 4-aminofluorescin-labelled poly(L-lysine citramide imide) in K562 cells. J Drug Target. 1998;5(3):193-206. doi:10.3109/10611869808995874. PMID: 9606009.

21: Durrieu F, Belloc F, Lacoste L, Dumain P, Chabrol J, Dachary-Prigent J, Morjani H, Boisseau MR, Reiffers J, Bernard P, Lacombe F. Caspase activation is an early event in anthracycline-induced apoptosis and allows detection of apoptotic cells before they are ingested by phagocytes. Exp Cell Res. 1998 May 1;240(2):165-75. doi: 10.1006/excr.1997.3918. PMID: 9596989.

20: Palissot V, Belhoussine R, Carpentier Y, Sebille S, Morjani H, Manfait M, Dufer J. Resistance to apoptosis induced by topoisomerase I inhibitors in multidrug-resistant HL60 leukemic cells. Biochem Biophys Res Commun. 1998 Apr 28;245(3):918-22. doi: 10.1006/bbrc.1998.8550. PMID: 9588215.

19: Benderra Z, Morjani H, Trussardi A, Manfait M. Role of the vacuolar H+-ATPase in daunorubicin distribution in etoposide-resistant MCF7 cells overexpressing the multidrug-resistance associated protein. Int J Oncol. 1998 Mar;12(3):711-5. doi: 10.3892/ijo.12.3.711. PMID: 9472114.

18: Belhoussine R, Morjani H, Lahlil R, Manfait M. Evidence for reversal of multidrug resistance by quinine in LR73 cells without alteration of nuclear pirarubicin uptake and down-regulation of mdr1 gene expression. Int J Cancer. 1997 Nov 14;73(4):600-6.. PMID: 9389578.

17: Millot C, Millot JM, Morjani H, Desplaces A, Manfait M. Characterization of acidic vesicles in multidrug-resistant and sensitive cancer cells by acridine orange staining and confocal microspectrofluorometry. J Histochem Cytochem. 1997 Sep;45(9):1255-64. doi: 10.1177/002215549704500909. PMID: 9283613.

16: Morjani H, Millot JM, Belhoussine R, Sebille S, Manfait M. Anthracycline subcellular distribution in human leukemic cells by microspectrofluorometry: factors contributing to drug-induced cell death and reversal of multidrug resistance. Leukemia. 1997 Jul;11(7):1170-9. doi: 10.1038/sj.leu.2400668. PMID:9205008.

15: Belhoussine R, Morjani H, Manfait M. Effet de la quinine sur la résistance multiple et la distribution intracellulaire de la pirarubicine dans les cellules tumorales LR73: étude comparative avec le vérapamil et le S9788 par microspectrofluorimétrie confocale laser Bull Cancer. 1997 Apr;84(4):343-9. French. PMID:9238156.

14: Chourpa I, Morjani H, Riou JF, Manfait M. Intracellular molecular interactions of antitumor drug amsacrine (m-AMSA) as revealed by surface-enhanced Raman spectroscopy. FEBS Lett. 1996 Nov 11;397(1):61-4. doi:10.1016/s0014-5793(96)01141-6. PMID: 8941714.

13: Morjani H, Pignon B, Vilque JP, Millot JM, Lartigue B, Simon G, Etienne JC, Potron G, Manfait M. Evaluation du phénotype de la résistance pléiotropique sur des prélèvements médullaires de patients présentant une leucémie aiguë par mesure de l'efflux nucléaire de la tétrahydropyranyl-doxorubicine. Approche par microspectrofluorimétrie confocale laser Ann Biol Clin (Paris). 1996;54(1):9-15. French. PMID: 8731789.

12: Pignon B, Morjani H, Vilque JP, Millot JM, Simon G, Lartigue B, Etienne JC, Potron G, Manfait M. In vitro study of THP-doxorubicin retention in human leukemic cells using confocal laser microspectrofluorometry. Leukemia. 1995 Aug;9(8):1361-7. PMID: 7643625.

11: Debal V, Allam N, Morjani H, Millot JM, Braguer D, Breillout F, Manfait M. Characterisation of a navelbine-resistant bladder carcinoma cell line cross-resistant to taxoids. Br J Cancer. 1994 Dec;70(6):1118-25. doi:10.1038/bjc.1994.458. PMID: 7981063; PMCID: PMC2033680.

10: Sebille S, Morjani H, Poullain MG, Manfait M. Effect of S9788, cyclosporin A and verapamil on intracellular distribution of THP-doxorubicin in multidrug-resistant K562 tumor cells, as studied by laser confocal microspectrofluorometry. Anticancer Res. 1994 Nov-Dec;14(6A):2389-93. PMID:7825978.

9: Debal V, Allam N, Morjani H, Millot JM, Gourdier B, Breillout F, Manfait M.Caractérisation du mécanisme de résistance croisée entre vincaalcaloïdes et taxoïdes dans la lignée de carcinome de vessie humain J82 Bull Cancer. 1994 Oct;81(10):891-3. French. PMID: 7734773.

8: Tarantilis PA, Morjani H, Polissiou M, Manfait M. Inhibition of growth and induction of differentiation of promyelocytic leukemia (HL-60) by carotenoids from Crocus sativus L. Anticancer Res. 1994 Sep-Oct;14(5A):1913-8. PMID:7847826.

7: Le Gal JM, Morjani H, Fardel O, Guillouzo A, Manfait M. Conformational changes in membrane proteins of multidrug-resistant K562 and primary rat hepatocyte cultures as studied by Fourier transform infrared spectroscopy. Anticancer Res. 1994 Jul-Aug;14(4A):1541-8. PMID: 7979183.

6: Morjani H, Riou JF, Nabiev I, Lavelle F, Manfait M. Molecular and cellular interactions between intoplicine, DNA, and topoisomerase II studied by surface-enhanced Raman scattering spectroscopy. Cancer Res. 1993 Oct 15;53(20):4784-90. PMID: 8402662.

5: Le Gal JM, Morjani H, Manfait M. Ultrastructural appraisal of the multidrug resistance in K562 and LR73 cell lines from Fourier transform infrared spectroscopy. Cancer Res. 1993 Aug 15;53(16):3681-6. PMID: 8339276.

4: Debal V, Morjani H, Millot JM, Angiboust JF, Gourdier B, Manfait M. Determination of vinorelbine (Navelbine) in tumour cells by high-performance liquid chromatography. J Chromatogr. 1992 Oct 2;581(1):93-9. doi:10.1016/0378-4347(92)80451-u. PMID: 1430011.

3: Morjani H, Pignon B, Millot JM, Debal V, Lamiable D, Potron G, Etienne JC, Manfait M. Intranuclear concentration measurements of doxorubicin in living leucocytes from patients treated for a lympho-proliferative disorder. Leuk Res. 1992 Jun-Jul;16(6-7):647-53. doi: 10.1016/0145-2126(92)90015-y. PMID: 1635383.

2: Nabiev IR, Morjani H, Manfait M. Selective analysis of antitumor drug interaction with living cancer cells as probed by surface-enhanced Raman spectroscopy. Eur Biophys J. 1991;19(6):311-6. doi: 10.1007/BF00183320. PMID:1915156.

1: Millot JM, Rasoanaivo TD, Morjani H, Manfait M. Role of the aclacinomycin A --doxorubicin association in reversal of doxorubicin resistance in K562 tumour cells. Br J Cancer. 1989 Nov;60(5):678-84. doi: 10.1038/bjc.1989.339. PMID:2803945; PMCID: PMC2247305.

Publications

Article dans une revue (57)

Biochemical and morpho-mechanical properties, and structural organization of rat tail tendon collagen in diet-induced obesity model Laurence van Gulick,Charles Saby,Claire Mayer,Emilie Fossier,Stéphane Jaissonet al. International Journal of Biological Macromolecules, 2024, 254, pp.127936. ⟨10.1016/j.ijbiomac.2023.127936⟩ Article dans une revue hal-05470946v1
Biochemical and morpho-mechanical properties, and structural organization of rat tail tendon collagen in diet-induced obesity model Laurence van Gulick,Charles Saby,Claire Mayer,Emilie Fossier,Stéphane Jaissonet al. International Journal of Biological Macromolecules, 2024, 254, pp.127936. ⟨10.1016/j.ijbiomac.2023.127936⟩ Article dans une revue hal-04988106v1
Raman imaging for monitoring deuterated squalene-gemcitabine nanomedicines in single living breast cancer cells Almar Al Assaad,Cherine Alaouta,Didier Desmaële,Emilie Buache,Emilie Fossieret al. International Journal of Pharmaceutics, 2024, 667, pp.124870. ⟨10.1016/j.ijpharm.2024.124870⟩ Article dans une revue hal-04929783v1
Molecular Links between Cancer and Metabolic Diseases: New Perspectives and Therapeutic Strategies for Cancer Prevention and Treatment by Targeting Nutritional Patterns and Metabolic Alterations Mohamed Zaiou,Hamid Morjani Cancers, 2023, 15 (4), pp.1350. ⟨10.3390/cancers15041350⟩ Article dans une revue hal-04319180v1
Design, Synthesis, Cytotoxic Effect Evaluation and Molecular Docking of (R)‐Camphor‐Based Thiazolidinone‐Isoxazole and Thiazolidinone‐1,2,3‐triazole Hybrids“ Abdellah N'Ait Ousidi,Abdoullah Bimoussa,Mohammed Loubidi,Mourad Fawzi,Yassine Laamariet al. ChemistrySelect, 2023, 8 (1), pp.e202203349. ⟨10.1002/slct.202203349⟩ Article dans une revue hal-04790719v1
Synthesis, characterization, molecular docking, and anticancer activities of new 1,3,4-oxadiazole-5-fluorocytosine hybrid derivatives Az-Eddine El Mansouri,Saida Lachhab,Ali Oubella,Mehdi Ahmad,Johan Neytset al. Journal of Molecular Structure, 2023, 1272, pp.134135. ⟨10.1016/j.molstruc.2022.134135⟩ Article dans une revue hal-03789531v1
Neuraminidase-1: A Sialidase Involved in the Development of Cancers and Metabolic Diseases Kévin Toussaint,Aline Appert-Collin,Hamid Morjani,Camille Albrecht,Hervé Sarteletet al. Cancers, 2022, 14, pp.4868. ⟨10.3390/cancers14194868⟩ Article dans une revue (article de synthèse) hal-04099812v1
New 1,2,3-Triazoles from (R)-Carvone: Synthesis, DFT Mechanistic Study and In Vitro Cytotoxic Evaluation Ali Oubella,Abdoullah Bimoussa,Abdellah N’ait Oussidi,Mourad Fawzi,Aziz Auhmaniet al. Molecules, 2022, 27 (3), pp.769. ⟨10.3390/molecules27030769⟩ Article dans une revue hal-03551211v1
An integrated approach to investigate age-related modifications of morphological, mechanical and structural properties of type I collagen Laurence van Gulick,Charles Saby,Stéphane Jaisson,Anaïs Okwieka,Philippe Gilleryet al. Acta Biomaterialia, 2022, 137, pp.64-78. ⟨10.1016/j.actbio.2021.10.020⟩ Article dans une revue hal-03607799v1
Design, Hemiysnthesis, crystal structure and anticancer activity of 1, 2, 3-triazoles derivatives of totarol Yassine Laamari,Ali Oubella,Abdoullah Bimoussa,Az-Eddine El Mansouri,El Mostafa Ketatniet al. Bioorganic Chemistry, 2021, 115, pp.105165. ⟨10.1016/j.bioorg.2021.105165⟩ Article dans une revue hal-03438882v1
Investigation of squalene-doxorubicin distribution and interactions within single cancer cell using Raman microspectroscopy Hassan Rammal,Almar Al Assaad,Franco Dosio,Barbara Stella,Andrei Maksimenkoet al. Nanomedicine: Nanotechnology, Biology and Medicine, 2021, 35, pp.102404. ⟨10.1016/j.nano.2021.102404⟩ Article dans une revue hal-03406418v1
The N and C-termini of SPCA2 regulate differently Kv10.1 function: role in the collagen 1-induced breast cancer cell survival Alban Girault,Marta Peretti,Mehdi Badaoui,Anais Hémon,Hamid Morjaniet al. American Journal of Cancer Research, 2021, 11 (1), pp.251+ Article dans une revue hal-03607831v1
New enaminone-based to the sesquiterpenic: TiCl4-catalyzed synthesis, spectral characterization, crystal structure, Hirshfeld surface analysis, DFT studies and cytotoxic activity Abdoullah Bimoussa,Ali Oubella,Mouhi Eddine Hachim,My Youssef Ait Itto,Olivier Mentréet al. Journal of Molecular Structure, 2021, 1241, pp.130622. ⟨10.1016/j.molstruc.2021.130622⟩ Article dans une revue hal-03438902v1
Design, synthesis, biological evaluation and molecular docking of new 1,3,4-oxadiazole homonucleosides and their double-headed analogs as antitumor agents Az-Eddine El Mansouri,Ali Oubella,Ahmad Mehdi,Moulay Youssef Aititto,Mohamed Zahouilyet al. Bioorganic Chemistry, 2021, 108, pp.104558. ⟨10.1016/j.bioorg.2020.104558⟩ Article dans une revue hal-03161709v1
LRP-1 Promotes Colon Cancer Cell Proliferation in 3D Collagen Matrices by Mediating DDR1 Endocytosis Cao Cuong Le,Amar Bennasroune,Guillaume Collin,Cathy Hachet,Véronique Lehrteret al. Frontiers in Cell and Developmental Biology, 2020, 8, ⟨10.3389/fcell.2020.00412⟩ Article dans une revue hal-02934154v1
Thrombospondin-1 Receptor CD47 Overexpression Contributes to P-Glycoprotein-Mediated Multidrug Resistance Against Doxorubicin in Thyroid Carcinoma FTC-133 Cells Marie-Pierre Courageot,Laurent Duca,Laurent Martiny,Emmanuelle Devarenne-Charpentier,Hamid Morjaniet al. Frontiers in Oncology, 2020, 10, ⟨10.3389/fonc.2020.551228⟩ Article dans une revue hal-03372837v1
Synthesis, characterization, and biological evaluation of new heterocyclic systems 1, 2, 3-triazole-isoxazoline from eugenol by the mixed condensation reactions Abdelmaoujoud Taia,Mohamed Essaber,Ali Oubella,Abdeljalil Aatif,Jacques Bodiguelet al. Synthetic Communications, 2020, 50 (13), pp.2052-2065. ⟨10.1080/00397911.2020.1762224⟩ Article dans une revue hal-03241095v1
Functional Interplay Between Collagen Network and Cell Behavior Within Tumor Microenvironment in Colorectal Cancer Cuong Cao Le,Amar Bennasroune,Benoît Langlois,Stéphanie Salesse,Camille Boulagnon-Rombiet al. Frontiers in Oncology, 2020, 10, ⟨10.3389/fonc.2020.00527⟩ Article dans une revue hal-03053593v1
Type I Collagen Aging Increases Expression and Activation of EGFR and Induces Resistance to Erlotinib in Lung Carcinoma in 3D Matrix Model Marie-Pierre Courageot,Laurent Duca,Laurent Martiny,Emmanuelle Devarenne-Charpentier,Hamid Morjaniet al. Frontiers in Oncology, 2020, 10, ⟨10.3389/FONC.2020.01593⟩ Article dans une revue hal-03164545v1
Effects of the Tumor Environment on Ion Channels: Implication for Breast Cancer Progression Halima Ouadid-Ahidouch,Hamid Morjani,Julie Schnipper,Alban Girault,Ahmed Ahidouchet al. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy [1994-..], 2020, 251, pp.119382. ⟨10.1007/112_2020_19⟩ Article dans une revue hal-03164510v1
Synthesis and Antitumor Activity of Novel Heterocyclic Systems with Monoterpenic Skeleton Combining Dichlorocyclopropane and 1,3,4‐Thiadiazole Nucleus Ali Oubella,Mourad Fawzi,Aziz Auhmani,Abdelkhalek Riahi,Hamid Morjaniet al. ChemistrySelect, 2020, 5 (21), pp.6403-6406. ⟨10.1002/slct.202001284⟩ Article dans une revue hal-02882951v1
Triterpene saponins from the roots of Parkia bicolor A. Chev Michel Boni Bitchi,Abdulmagid Alabdul-Magid,Philomène Akoua Yao-Kouassi,Faustin Aka Kabran,Dominique Harakatet al. Fitoterapia, 2019, 137, pp.104264. ⟨10.1016/j.fitote.2019.104264⟩ Article dans une revue hal-02310366v1
Original association of ion transporters mediates the ECM-induced breast cancer cell survival: Kv10.1-Orai1-SPCA2 partnership Marta Peretti,Mehdi Badaoui,Alban Girault,Laurence van Gulick,Marie-Pierre Mabilleet al. Scientific Reports, 2019, 9 (1), pp.1175. ⟨10.1038/s41598-018-37602-7⟩ Article dans une revue hal-02310333v1
Age-related changes in molecular organization of type I collagen in tendon as probed by polarized SHG and Raman microspectroscopy Laurence van Gulick,Charles Saby,Hamid Morjani,Abdelilah Beljebbar Scientific Reports, 2019, 9 (1), ⟨10.1038/s41598-019-43636-2⟩ Article dans une revue hal-02309301v1
Triterpenes from Salvia argentea var. aurasiaca and their antibacterial and cytotoxic activities Sara Bechkri,Abdulmagid Alabdul-Magid,Laurence Voutquenne-Nazabadioko,Berrehal Djemaa,Ahmed Kaboucheet al. Fitoterapia, 2019, pp.104296. ⟨10.1016/j.fitote.2019.104296⟩ Article dans une revue hal-02310372v1
Isolation and structure elucidation of cyclopeptide alkaloids from the leaves of Heisteria parvifolia Michel Boni Bitchi,Abdulmagid Alabdul-Magid,Faustin Aka Kabran,Philomène Akoua Yao-Kouassi,Dominique Harakatet al. Phytochemistry, 2019, 167, pp.112081. ⟨10.1016/j.phytochem.2019.112081⟩ Article dans une revue hal-02310316v2
Diastereoselective synthesis and cytotoxic evaluation of new isoxazoles and pyrazoles with monoterpenic skeleton Ali Oubella,My Youssef Ait Itto,Aziz Auhmani,Abdelkhalek Riahi,Anthony Robertet al. Journal of Molecular Structure, 2019, 1198, pp.126924. ⟨10.1016/j.molstruc.2019.126924⟩ Article dans une revue istex hal-02430280v1
DDR1 and MT1-MMP Expression Levels Are Determinant for Triggering BIK-Mediated Apoptosis by 3D Type I Collagen Matrix in Invasive Basal-Like Breast Carcinoma Cells Charles Saby,Guillaume Collin,Maha Sinane,Emilie Buache,Laurence van Gulicket al. Frontiers in Pharmacology, 2019, 10, ⟨10.3389/fphar.2019.00462⟩ Article dans une revue hal-02309321v1
Antibacterial, antioxidant and cytotoxic activities of triterpenes and flavonoids from the aerial parts of Salvia barrelieri Etl. Meryem Lehbili,Abdulmagid Alabdul Magid,Ahmed Kabouche,Laurence Voutquenne-Nazabadioko,Amin Abediniet al. Natural Product Research, 2018, 32 (22), pp.2683-2691. ⟨10.1080/14786419.2017.1378207⟩ Article dans une revue hal-02008123v1
Triterpenoid saponins from Scabiosa stellata collected in North-eastern Algeria Meryem Lehbili,Abdulmagid Alabdul Magid,Ahmed Kabouche,Laurence Voutquenne-Nazabadioko,Hamid Morjaniet al. Phytochemistry, 2018, 150, pp.40-49. ⟨10.1016/j.phytochem.2018.03.005⟩ Article dans une revue hal-03351420v1
Two new bis-iridoids isolated from Scabiosa stellata and their antibacterial, antioxidant, anti-tyrosinase and cytotoxic activities Meryem Lehbili,Abdulmagid Alabdul Magid,Jane Hubert,Ahmed Kabouche,Laurence Voutquenne-Nazabadiokoet al. Fitoterapia, 2018, 125, pp.41 - 48. ⟨10.1016/j.fitote.2017.12.018⟩ Article dans une revue hal-03351296v1
A new 2-alkylhydroquinone glucoside from Phagnalon saxatile (L.) Cass Hanene Cherchar,Meriem Lehbili,Djemaa Berrehal,Hamid Morjani,Abdulmagid Alabdul Magidet al. Natural Product Research, 2018, 32 (9), pp.1010-1016. ⟨10.1080/14786419.2017.1375918⟩ Article dans une revue hal-02929189v1
Collagen type 1 promotes survival of human breast cancer cells by overexpressing Kv10.1 potassium and Orai1 calcium channels through DDR1-dependent pathway Mehdi Badaoui,Cloé Mimsy-Julienne,Charles Saby,Laurence van Gulick,Marta Perettiet al. Oncotarget, 2018, 9 (37), ⟨10.18632/oncotarget.19065⟩ Article dans une revue hal-02310419v1
Age-related modifications of type I collagen impair DDR1-induced apoptosis in non-invasive breast carcinoma cells Charles Saby,Hassan Rammal,Kevin Magnien,Emilie Buache,Sylvie Brassart-Pascoet al. Cell Adhesion and Migration, 2018, 12 (4), pp.335-347. ⟨10.1080/19336918.2018.1472182⟩ Article dans une revue hal-02365694v1
Single cell adhesion strength assessed with variable-angle total internal reflection fluorescence microscopy Marcelina Cardoso dos Santos,Cyrille Vézy,Hamid Morjani,Rodolphe Jaffiol AIMS Biophysics, 2017, 4 (3), pp.438-450. ⟨10.3934/biophy.2017.3.438⟩ Article dans une revue hal-02448485v1
How Streptomyces anulatus Primes Grapevine Defenses to Cope with Gray Mold: A Study of the Early Responses of Cell Suspensions Parul Vatsa-Portugal,Aziz Aziz,Marine Rondeau,Sandra Villaume,Hamid Morjaniet al. Frontiers in Plant Science, 2017, 8, ⟨10.3389/fpls.2017.01043⟩ Article dans une revue hal-02929447v1
A new gallium complex inhibits tumor cell invasion and matrix metalloproteinase MMP-14 expression and activity Ahmed Mohsen,Philippe Collery,Roselyne Garnotel,Bertrand Brassart,Nicolas Etiqueet al. Metallomics, 2017, 9 (8), pp.1176-1184. ⟨10.1039/c7mt00049a⟩ Article dans une revue hal-02929237v1
Role of LRP-1 in cancer cell migration in 3-dimensional collagen matrix Aline Appert-Collin,Amar Bennasroune,Pierre Jeannesson,Christine Terryn,Guy Fuhrmannet al. Cell Adhesion and Migration, 2017, 11 (4), pp.316-326. ⟨10.1080/19336918.2016.1215788⟩ Article dans une revue hal-02184497v1
Tomentosin Induces Telomere Shortening and Caspase-Dependant Apoptosis in Cervical Cancer Cells Nawel Merghoub,Hassan El Btaouri,Laila Benbacer,Saïd Gmouh,Chantal Trentesauxet al. Journal of Cellular Biochemistry, 2017, 118 (7), pp.1689-1698. ⟨10.1002/jcb.25826⟩ Article dans une revue hal-02183182v1
Oleanane-type triterpene saponins from Calendula stellata Meryem Lehbili,Abdulmagid Alabdul Magid,Ahmed Kabouche,Laurence Voutquenne-Nazabadioko,Amin Abediniet al. Phytochemistry, 2017, 144, pp.33 - 42. ⟨10.1016/j.phytochem.2017.08.015⟩ Article dans une revue hal-01834101v1
Isolation and characterisation of cytotoxic compounds from Euphorbia clementei Boiss. Abbes Benmerache,Abdulmagid Alabdul Magid,Amira Labed,Ahmed Kabouche,Laurence Voutquenne-Nazabadiokoet al. Natural Product Research, 2017, 31 (18), pp.2091 - 2098. ⟨10.1080/14786419.2016.1277345⟩ Article dans une revue hal-01834095v1
Triterpene glycosides from the aerial parts of Gouania longipetala Diane Patricia Apie Gossan,Abdulmagid Alabdul Magid,Philomène Akoua Yao-Kouassi,Antoine Ahibo Coffy,Jérôme Josseet al. Phytochemistry, 2017, 134, pp.71 - 77. ⟨10.1016/j.phytochem.2016.11.004⟩ Article dans une revue hal-01834083v1
Corrigendum: Discoidin Domain Receptors: Potential Actors and Targets in Cancer Marie-Pierre Courageot,Laurent Duca,Laurent Martiny,Emmanuelle Devarenne-Charpentier,Hassan Rammalet al. Frontiers in Pharmacology, 2016, 7, ⟨10.3389/fphar.2016.00346⟩ Article dans une revue hal-03150780v1
Type I collagen aging impairs discoidin domain receptor 2-mediated tumor cell growth suppression Charles Saby,Emilie Buache,Sylvie Brassart-Pasco,Hassan El Btaouri,Marie-Pierre Courageotet al. Oncotarget, 2016, 7 (18), pp.24908-24927. ⟨10.18632/oncotarget.8795⟩ Article dans une revue hal-03150784v1
Antibacterial and cytotoxic triterpenoids from the roots of Combretum racemosum Diane Patricia Apie Gossan,Abdulmagid Alabdul Magid,Philomène Akoua Yao-Kouassi,Jérôme Josse,Sophie C. Gangloffet al. Fitoterapia, 2016, 110, pp.89 - 95. ⟨10.1016/j.fitote.2016.03.002⟩ Article dans une revue hal-01833994v1
Discoidin Domain Receptors: Potential Actors and Targets in Cancer Hassan Rammal,Charles Saby,Kevin Magnien,Laurence Van-Gulick,Roselyne Garnotelet al. Frontiers in Pharmacology, 2016, 7, ⟨10.3389/fphar.2016.00055⟩ Article dans une revue hal-03150788v1
Inula Viscosa Extracts Induces Telomere Shortening and Apoptosis in Cancer Cells and Overcome Drug Resistance Nawal Merghoub,Hassan El Btaouri,Laila Benbacer,Saïd Gmouh,Chantal Trentesauxet al. Nutrition and Cancer, 2015, 68 (1), pp.131-143. ⟨10.1080/01635581.2016.1115105⟩ Article dans une revue hal-03599262v1
Triterpenoid glycosides from the leaves of Meliosma henryi. Abdulmagid Alabdul Magid,Hamid Morjani,Dominique Harakat,Claudie Madoulet,Vincent Dumontetet al. Phytochemistry, 2014, 109, pp.49-56 Article dans une revue hal-01113162v1
Microfluidity mapping using fluorescence correlation spectroscopy: A new way to investigate plasma membrane microorganization of living cells Pascale Winckler,Aurélie Cailler,Régis Deturche,Pierre Jeannesson,Hamid Morjaniet al. Biochimica et Biophysica Acta:Biomembranes, 2012, 1818 (11), pp.2477-2485. ⟨10.1016/j.bbamem.2012.05.018⟩ Article dans une revue hal-02383196v1
Extracellular Matrix Proteins Modulate Antimigratory and Apoptotic Effects of Doxorubicin Georges Said,Marie Guilbert,Hamid Morjani,Roselyne Garnotel,Pierre Jeannessonet al. Chemotherapy Research and Practice, 2012, 2012, pp.268681. ⟨10.1155/2012/268681⟩ Article dans une revue (article de synthèse) hal-04748331v1
Accumulation of lactosylceramide and overexpression of a PSC833-resistant P-glycoprotein in multidrug-resistant human sarcoma cells. Nassera Aouali,Hassan El Btaouri,Charles Dumontet,Lahcen Eddabra,Sophie Malagarie-Cazenaveet al. Oncology Reports, 2011, 25 (4), pp.1161-7. ⟨10.3892/or.2011.1180⟩ Article dans une revue hal-00771766v1
Telomestatin-induced Telomere Uncapping Is Modulated by POT1 through G-overhang Extension in HT1080 Human Tumor Cells Dennis Gomez,Thomas Wenner,Bertrand Brassart,Céline Douarre,Marie-Françoise O'Donohueet al. Journal of Biological Chemistry, 2006, 281 (50), pp.38721-38729. ⟨10.1074/jbc.M605828200⟩ Article dans une revue hal-02328255v1
Overexpression of Bcl-2 is associated with apoptotic resistance to the G-quadruplex ligand 12459 but is not sufficient to confer resistance to long-term senescence Céline Douarre,Dennis Gomez,Hamid Morjani,Jean-Marie Zahm,Marie-Françoise O'Donohueet al. Nucleic Acids Research, 2005, 33 (7), pp.2192-2203. ⟨10.1093/nar/gki514⟩ Article dans une revue hal-02328296v1
Overexpression of Bcl-2 is associated with apoptotic resistance to the G-quadruplex ligand 12459 but is not sufficient to confer resistance to long-term senescence. Céline Douarre,Dennis Gomez,Hamid Morjani,Jean-Marie Zahm,Marie-Françoise O'Donohueet al. Nucleic Acids Research, 2005, 33 (7), pp.2192-203. ⟨10.1093/nar/gki514⟩ Article dans une revue inserm-00145639v1
Régulation de la longueur des télomères : rendre le télomère accessible ? Jean-François Riou,Dennis Gomez,Jean-Louis Mergny,Lionel Guittat,Rajaa Paterskiet al. Bulletin du Cancer, 2005 Article dans une revue hal-02050294v1
Impact of endogenous nitric oxide on microglial cell energy metabolism and labile iron pool. Benoît Chénais,Hamid Morjani,Jean-Claude Drapier Journal of Neurochemistry, 2002, 81 (3), pp.615-23 Article dans une revue hal-00422911v1
Free radical production and labile iron pool decrease triggered by subtoxic concentration of aclarubicin in human leukemia cell lines. Doriane Richard,Hamid Morjani,Benoît Chénais Leukemia Research, 2002, 26 (10), pp.927-31 Article dans une revue hal-00422915v1

Chapitre d'ouvrage (1)

Effects of the Tumor Environment on Ion Channels: Implication for Breast Cancer Progression Halima Ouadid-Ahidouch,Hamid Morjani,Julie Schnipper,Alban Girault,Ahmed Ahidouch Stock, C and Pardo, LA. TRANSPORTOME MALFUNCTION IN THE CANCER SPECTRUM: ION TRANSPORT IN TUMOR BIOLOGY, 181, Springer International Publishing, pp.1-38, 2021, Reviews of Physiology Biochemistry and Pharmacology, 978-3-030-90920-8; 978-3-030-90919-2. ⟨10.1007/112_2020_19⟩ Chapitre d'ouvrage hal-03620586v1