Hubert Lincet

36
Documents

Publications

Publications

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Identification of a miRNA multi-targeting therapeutic strategy in glioblastoma

Arthur Bassot , Helena Dragic , Sarah Al Haddad , Laurine Moindrot , Soline Odouard et al.
Cell Death and Disease, 2023, 14, ⟨10.1038/s41419-023-06117-z⟩
Article dans une revue hal-04231610 v1

The strategic roles of four enzymes in the interconnection between metabolism and oncogene activation in non-small cell lung cancer: Therapeutic implications

Philippe Icard , Luca Simula , Ludovic Fournel , Karen Leroy , Audrey Lupo et al.
Drug Resistance Updates, 2022, 63, pp.100852. ⟨10.1016/j.drup.2022.100852⟩
Article dans une revue hal-05366101 v1
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The key role of Warburg effect in SARS-CoV-2 replication and associated inflammatory response

Philippe Icard , Hubert Lincet , Zherui Wu , Antoine Coquerel , Patricia Forgez et al.
Biochimie, 2021, 180, pp.169 - 177. ⟨10.1016/j.biochi.2020.11.010⟩
Article dans une revue hal-03492831 v1
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Understanding the Central Role of Citrate in the Metabolism of Cancer Cells and Tumors: An Update

Philippe Icard , Antoine Coquerel , Zherui Wu , Joseph Gligorov , David Fuks et al.
International Journal of Molecular Sciences, 2021, 22 (12), pp.6587. ⟨10.3390/ijms22126587⟩
Article dans une revue hal-03278150 v1

Metabolic Strategies for Inhibiting Cancer Development

Philippe Icard , Mauro Loi , Zherui Wu , Antonin Ginguay , Hubert Lincet et al.
Advances in Nutrition, 2021, 12 (4), pp.1461-1480. ⟨10.1093/advances/nmaa174⟩
Article dans une revue hal-05418296 v1

Why may citrate sodium significantly increase the effectiveness of transarterial chemoembolization in hepatocellular carcinoma?

Philippe Icard , Luca Simula , Zherui Wu , Diana Berzan , Philippe Sogni et al.
Drug Resistance Updates, 2021, 59, pp.100790. ⟨10.1016/j.drup.2021.100790⟩
Article dans une revue hal-05418290 v1
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Lipoic acid a multi-level molecular inhibitor of tumorigenesis

D. Farhat , Hubert Lincet
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2020, 1873, pp.188317 -. ⟨10.1016/j.bbcan.2019.188317⟩
Article dans une revue hal-03488739 v1

Lipoic acid-induced oxidative stress abrogates IGF-1R maturation by inhibiting the CREB/furin axis in breast cancer cell lines

Diana Farhat , Sandra Ghayad , Philippe Icard , Muriel Le Romancer , Nader Hussein et al.
Oncogene, 2020, 39 (17), pp.3604-3610. ⟨10.1038/s41388-020-1211-x⟩
Article dans une revue hal-03869503 v1
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ATP citrate lyase: A central metabolic enzyme in cancer

Philippe Icard , Zherui Wu , Ludovic Fournel , Antoine Coquerel , Hubert Lincet et al.
Cancer Letters, 2020, 471, pp.125 - 134. ⟨10.1016/j.canlet.2019.12.010⟩
Article dans une revue hal-03488730 v1

Lipoic acid decreases breast cancer cell proliferation by inhibiting IGF-1R via furin downregulation

Diana Farhat , Sophie Léon , Sandra Ghayad , Nicolas Gadot , Philippe Icard et al.
British Journal of Cancer, 2020, 122 (6), pp.885-894. ⟨10.1038/s41416-020-0729-6⟩
Article dans une revue hal-03869488 v1
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Interconnection between Metabolism and Cell Cycle in Cancer

Philippe Icard , Ludovic Fournel , Zherui Wu , Marco Alifano , Hubert Lincet
Trends in Biochemical Sciences, 2019, 44, pp.490 - 501. ⟨10.1016/j.tibs.2018.12.007⟩
Article dans une revue hal-03484455 v1
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Citrate targets FBPase and constitutes an emerging novel approach for cancer therapy

Philippe Icard , Ludovic Fournel , Antoine Coquerel , Joseph Gligorov , Marco Alifano et al.
Cancer Cell International, 2018, 18 (1), pp.175. ⟨10.1186/s12935-018-0676-y⟩
Article dans une revue hal-05418305 v1

Extracellular Citrate and Cancer Metabolism-Letter

Philippe Icard , Ludovic Fournel , Marco Alifano , Hubert Lincet
Cancer Research, 2018, 78 (17), pp.5176-5176. ⟨10.1158/0008-5472.CAN-18-1666⟩
Article dans une revue inserm-02099898 v1

Sarcopenia in resected non-small cell lung cancer: let’s move to patient-directed strategies

Philippe Icard , Antonio Iannelli , Hubert Lincet , Marco Alifano
Journal of Thoracic Disease, 2018, 10 (S26), pp.S3138-S3142. ⟨10.21037/jtd.2018.08.34⟩
Article dans une revue hal-05418311 v1

How the Warburg effect supports aggressiveness and drug resistance of cancer cells?

Philippe Icard , Seth Shulman , Diana Farhat , Jean-Marc Steyaert , Marco Alifano et al.
Drug Resistance Updates, 2018, 38, pp.1-11. ⟨10.1016/j.drup.2018.03.001⟩
Article dans une revue istex inserm-02096107 v1
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The reduced concentration of citrate in cancer cells: An indicator of cancer aggressiveness and a possible therapeutic target

Icard Philippe , Lincet Hubert
Drug Resistance Updates, 2016, 29, pp.47 - 53. ⟨10.1016/j.drup.2016.09.003⟩
Article dans une revue inserm-01427151 v1
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Lipoic acid decreases Mcl-1, Bcl-xL and up regulates Bim on ovarian carcinoma cells leading to cell death

Perrine Kafara , Philippe Icard , Marilyne Guillamin , Laurent Schwartz , Hubert Lincet
Journal of Ovarian Research, 2015, 8, pp.36. ⟨10.1186/s13048-015-0165-z⟩
Article dans une revue inserm-01187953 v1
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The dark side of ZNF217, a key regulator of tumorigenesis with powerful biomarker value

Pascale A Cohen , Caterina F Donini , Nhan T Nguyen , Hubert Lincet , Julie A Vendrell
Oncotarget, 2015, 6 (39), pp.41566-81. ⟨10.18632/oncotarget.5893⟩
Article dans une revue inserm-01427161 v1

Metabolic Treatment of Cancer: Intermediate Results of a Prospective Case Series

Schwartz Laurent , Buhler Ludivine , Icard Philippe , Lincet Hubert , Jean-Marc Steyaert
Anticancer Research, 2014
Article dans une revue hal-00933725 v1
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The metabolic cooperation between cells in solid cancer tumors

Philippe Icard , Perrine Kafara , Jean-Marc Steyaert , Laurent Schwartz , Hubert Lincet
BBA - Biochimica et Biophysica Acta, 2014, 1846 (1), pp.216 - 225. ⟨10.1016/j.bbcan.2014.06.002⟩
Article dans une revue inserm-01427178 v1
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How do glycolytic enzymes favour cancer cell proliferation by nonmetabolic functions?

Hubert Lincet , Philippe Icard
Oncogene, 2014, 34 (29), pp.3751 - 3759. ⟨10.1038/onc.2014.320⟩
Article dans une revue inserm-01427176 v1

La tumeur cancéreuse : un parasite métabolique ?

Philippe Icard , Hubert Lincet
Bulletin du Cancer, 2013, 100 (5), pp.427-433. ⟨10.1684/bdc.2013.1742⟩
Article dans une revue hal-05418386 v1

Inhibition of Mcl-1 expression by citrate enhances the effect of Bcl-xL inhibitors on human ovarian carcinoma cells

Hubert Lincet , Perrine Kafara , Florence Giffard , Edwige Abeilard-Lemoisson , Maryline Duval et al.
Journal of Ovarian Research, 2013, 6 (1), pp.72. ⟨10.1186/1757-2215-6-72⟩
Article dans une revue hal-05418378 v1

A global view of the biochemical pathways involved in the regulation of the metabolism of cancer cells

Philippe Icard , Hubert Lincet
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2012, 1826 (2), pp.423-433. ⟨10.1016/j.bbcan.2012.07.001⟩
Article dans une revue istex hal-05418444 v1

siPGK1 sensitizes chemoresistant human ovarian cancer cell lines to cisplatin

Charlotte Lepleux , Edwige Abeilard-Lemoisson , Maryline Duval , Icard Philippe , Hubert Lincet
Anticancer Research, 2012, 32 (10), pp.4277-86
Article dans une revue hal-05421814 v1

Experimental results using 3-bromopyruvate in mesothelioma: in vitro and in vivo studies

Icard Philippe , Zhang Xiao-Dong , Lemoisson Edwige , Louis Marie-Hélène , Allouche Stéphane et al.
Journal of Bioenergetics and Biomembranes, 2012, 44 (1), pp.81-90. ⟨10.1007/s10863-012-9415-6⟩
Article dans une revue istex hal-05421836 v1

Understanding the central role of citrate in the metabolism of cancer cells

Philippe Icard , Laurent Poulain , Hubert Lincet
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2012, 1825 (1), pp.111-116. ⟨10.1016/j.bbcan.2011.10.007⟩
Article dans une revue istex hal-05421849 v1

Citrate induces apoptotic cell death: a promising way to treat gastric carcinoma?

Yunfei Lu , Xiaodong Zhang , Haitian Zhang , Jiao Lan , Guangwu Huang et al.
Anticancer Research, 2011, 31 (3), pp.797-805
Article dans une revue hal-05418478 v1

Absence of Bcl-xL down-regulation in response to cisplatin is associated with chemoresistance in ovarian carcinoma cells☆

M Villedieu , M Louis , S Dutoit , E Brotin , Hubert Lincet et al.
Gynecologic Oncology, 2007, 105 (1), pp.31-44. ⟨10.1016/j.ygyno.2006.12.011⟩
Article dans une revue istex hal-05421859 v1

A proteomic kinetic analysis of IGROV1 ovarian carcinoma cell line response to cisplatin treatment.

Karen Le Moguen , Hubert Lincet , Paulo Marcelo , Edwige Lemoisson , Natacha Heutte et al.
Proteomics, 2007, 7 (22), pp.4090-101. ⟨10.1002/pmic.200700231⟩
Article dans une revue istex hal-00196070 v1

Comparative proteomic analysis of cisplatin sensitive IGROV1 ovarian carcinoma cell line and its resistant counterpart IGROV1‐R10

Karen Le Moguen , Hubert Lincet , Edwige Deslandes , Marie Hubert-Roux , Catherine Lange et al.
Proteomics, 2006, 6 (19), pp.5183-5192. ⟨10.1002/pmic.200500925⟩
Article dans une revue istex hal-05421970 v1

The cyclin-dependent kinase inhibitor p21cip1/waf1 enhances the cytotoxicity of ganciclovir in HSV-tk transfected ovarian carcinoma cells

Christelle Ziller , Hubert Lincet , Christian Muller , Cathy Staedel , Jean-Paul Behr et al.
Cancer Letters, 2004, 212 (1), pp.43-52. ⟨10.1016/j.canlet.2004.03.048⟩
Article dans une revue istex hal-04978064 v1

Acquisition of chemoresistance in a human ovarian carcinoma cell line is linked to a defect in cell cycle control

Laurent Poulain , Hubert Lincet , Françoise Duigou , Edwige Deslandes , François Sichel et al.
International Journal of Cancer, 1998, 78 (4), pp.454-463. ⟨10.1002/(sici)1097-0215(19981109)78:4<454::aid-ijc11>3.0.co;2-6⟩
Article dans une revue hal-05421983 v1

Recherche de marqueurs prédictifs de résistance des tumeurs ovariennes aux chimiothérapies par imagerie MALDI

Blandine Charoy , Hubert Lincet , Regis Lavigne , Theodore Alexandrov , Hertbert Thiele et al.
Congrès annuel de la Société Française d'Electrophorèse et d'Analyse Protéomique, Sep 2010, Marseille, France
Communication dans un congrès hal-00658901 v1

Comparative proteomic analysis of cisplatin sensitive OAW42 epithelial ovarian cancer and its resistant counterpart OAW42-R by DIGE : proteomic profil

Hubert Lincet , Blandine Charoy , Charles Pineau , Edwige Lemoisson , Laurent Poulain et al.
4ème Congrès Spectrométrie de masse et analyse Protéomique, Sep 2009, Dijon, France
Communication dans un congrès hal-00668778 v1

DIGE-based comparison of sensitive versus resistant ovarian carcinoma cell lines : proteomics profiles for prediction of chemoresistance

Hubert Lincet , Blandine Charoy , Charles Pineau , Edwige Lemoisson , Laurent Poulain et al.
25ème Congrès de la Société Française d'Electrophorèse et d'Analyse Protéomique, 06-08 octobre 2008, Tours, France, Oct 2008, Tours, France
Communication dans un congrès hal-00668629 v1