Paola Minoprio

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Publications

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Prodrugs as new therapies against Chagas disease: In vivo synergy between Trypanosoma cruzi proline racemase inhibitors and benznidazole

Guilherme Dias de Melo , Nicolas Coatnoan , Nicolas Gouault , Jean-François Cupif , Jacques Renault et al.

Journal of Global Antimicrobial Resistance, 2022, 28, pp.84-89. ⟨10.1016/j.jgar.2021.10.030⟩

Article dans une revue hal-03504248v1
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Hemorrhagic fever viruses: Pathogenesis, therapeutics, and emerging and re-emerging potential

Lizdany Flórez-Álvarez , Edmarcia Elisa de Souza , Viviane Fongaro Botosso , Danielle Bruna Leal de Oliveira , Paulo Lee Ho et al.

Frontiers in Microbiology, 2022, 13, pp.1040093. ⟨10.3389/fmicb.2022.1040093⟩

Article dans une revue hal-04627470v1
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Highly Diverse Arenaviruses in Neotropical Bats, Brazil

Luiz Gustavo Bentim Góes , Carlo Fischer , Angélica Cristine Almeida Campos , Cristiano de Carvalho , Andrés Moreira-Soto et al.

Emerging Infectious Diseases, 2022, 28 (12), pp.2528-2533. ⟨10.3201/eid2812.220980⟩

Article dans une revue hal-04627410v1
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Automatic detection of the parasite Trypanosoma cruzi in blood smears using a machine learning approach applied to mobile phone images

Mauro César Cafundó Morais , Diogo Silva , Matheus Marques Milagre , Maykon Tavares De Oliveira , Thaís Pereira et al.

PeerJ, 2022, 10, pp.e13470. ⟨10.7717/peerj.13470⟩

Article dans une revue hal-04627513v1

Evaluation of the effectiveness of UV-C dose for photoinactivation of SARS-CoV-2 in contaminated N95 respirator, surgical and cotton fabric masks

Patrícia Metolina , Lilian Gomes de Oliveira , Bruno Ramos , Yan de Souza Angelo , Paola Minoprio et al.

Photochemical & Photobiological Sciences , 2022, 21 (11), pp.1915-1929. ⟨10.1007/s43630-022-00268-2⟩

Article dans une revue hal-04627493v1
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An international, interlaboratory ring trial confirms the feasibility of an extraction-less “direct” RT-qPCR method for reliable detection of SARS-CoV-2 RNA in clinical samples

Margaret Mills , Emily Bruce , Meei-Li Huang , Jessica Crothers , Ollivier Hyrien et al.

PLoS ONE, 2022, 17 (1), pp.e0261853. ⟨10.1371/journal.pone.0261853⟩

Article dans une revue hal-04627589v2
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Colorimetric RT-LAMP SARS-CoV-2 diagnostic sensitivity relies on color interpretation and viral load

Mateus Nóbrega Aoki , Bruna de Oliveira Coelho , Luiz Gustavo Bentim Góes , Paola Minoprio , Edison Luiz Durigon et al.

Scientific Reports, 2021, 11 (1), pp.9026. ⟨10.1038/s41598-021-88506-y⟩

Article dans une revue hal-04627604v1
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In-depth analysis of laboratory parameters reveals the interplay between sex, age, and systemic inflammation in individuals with COVID-19

Felipe Ten-Caten , Patrícia Gonzalez-Dias , Ícaro Castro , Rodrigo L.T. Ogava , Jeevan Giddaluru et al.

International Journal of Infectious Diseases, 2021, 105, pp.579-587. ⟨10.1016/j.ijid.2021.03.016⟩

Article dans une revue hal-04627607v1
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Atypical Prolonged Viral Shedding With Intra-Host SARS-CoV-2 Evolution in a Mildly Affected Symptomatic Patient

Marielton dos Passos Cunha , Ana Paula Pessoa Vilela , Camila Vieira Molina , Stephanie Maia Acuña , Sandra Marcia Muxel et al.

Frontiers in Medicine, 2021, 8, pp.760170. ⟨10.3389/fmed.2021.760170⟩

Article dans une revue hal-04627601v1
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A comparative in silico linear B-cell epitope prediction and characterization for South American and African Trypanosoma vivax strains

Rafael Lucas Muniz Guedes , Carla Monadeli Filgueira Rodrigues , Nicolas Coatnoan , Alain Cosson , Fabiano Antonio Cadioli et al.

Genomics, 2019, 111 (3), pp.407-417. ⟨10.1016/j.ygeno.2018.02.017⟩

Article dans une revue pasteur-04628866v1
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Designed mono- and di-covalent inhibitors trap modeled functional motions for Trypanosoma cruzi proline racemase in crystallography

Patricia de Aguiar Amaral , Delphine Autheman , Guilherme Dias de Melo , Nicolas Gouault , Jean-François Cupif et al.

PLoS Neglected Tropical Diseases, 2018, 12 (10), ⟨10.1371/journal.pntd.0006853⟩

Article dans une revue hal-01935360v1

Imaging visceral leishmaniasis in real time with golden hamster model: Monitoring the parasite burden and hamster transcripts to further characterize the immunological responses of the host

Eline Rouault , Hervé Lecoeur , Asma Ben Meriem , Paola Minoprio , Sophie Goyard et al.

Parasitology International, 2017, 66 (1), pp.933-939. ⟨10.1016/j.parint.2016.10.020⟩

Article dans une revue pasteur-04628880v1
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Global Gene Expression Profiling through the Complete Life Cycle of Trypanosoma vivax

Andrew Jackson , Sophie Goyard , Dong Xia , Bernardo Foth , Mandy Sanders et al.

PLoS Neglected Tropical Diseases, 2015, 9 (8), pp.e0003975. ⟨10.1371/journal.pntd.0003975⟩

Article dans une revue pasteur-04628886v1
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Phylogenetic and syntenic data support a single horizontal transference to a Trypanosoma ancestor of a prokaryotic proline racemase implicated in parasite evasion from host defences

Zuleima Caballero , Andre Costa-Martins , Robson Ferreira , João P Alves , Myrna Serrano et al.

Parasites & Vectors, 2015, 8 (1), pp.222. ⟨10.1186/s13071-015-0829-y⟩

Article dans une revue pasteur-04628888v1
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In vivo imaging of trypanosomes for a better assessment of host–parasite relationships and drug efficacy

S. Goyard , P. Lourenço Dutra , P. Deolindo , D. Autheman , S. d'Archivio et al.

Parasitology International, 2014, 63 (1), pp.260-268. ⟨10.1016/j.parint.2013.07.011⟩

Article dans une revue pasteur-04628893v1
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Combined approaches for drug design points the way to novel proline racemase inhibitor candidates to fight Chagas' disease.

Armand Berneman , Lory Montout , Sophie Goyard , Nathalie Chamond , Alain Cosson et al.

PLoS ONE, 2013, 8 (4), pp.e60955. ⟨10.1371/journal.pone.0060955⟩

Article dans une revue hal-00833388v1
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Non-Invasive In Vivo Study of the Trypanosoma vivax Infectious Process Consolidates the Brain Commitment in Late Infections

Simon d'Archivio , Alain Cosson , Mathieu Medina , Thierry Lang , Paola Minoprio et al.

PLoS Neglected Tropical Diseases, 2013, 7 (1), pp.e1976. ⟨10.1371/journal.pntd.0001976⟩

Article dans une revue pasteur-04628899v1
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Drug Discovery Targeting Amino Acid Racemases

Paola Conti , Lucia Tamborini , Andrea Pinto , Arnaud Blondel , Paola Minoprio et al.

Chemical Reviews, 2011, 111 (11), pp.6919-6946. ⟨10.1021/cr2000702⟩

Article dans une revue pasteur-02510858v1
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Trypanosoma vivax infections: pushing ahead with mouse models for the study of Nagana. I. Parasitological, hematological and pathological parameters

Nathalie Chamond , Alain Cosson , Marie Christine Blom-Potar , Grégory Jouvion , Simon d'Archivio et al.

PLoS Neglected Tropical Diseases, 2010, 4 (8), pp.e792. ⟨10.1371/journal.pntd.0000792⟩

Article dans une revue hal-02544358v1
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Trypanosoma vivax infections: pushing ahead with mouse models for the study of Nagana. II. Immunobiological dysfunctions

Marie Christine Blom-Potar , Nathalie Chamond , Alain Cosson , Grégory Jouvion , Sabrina Droin-Bergère et al.

PLoS Neglected Tropical Diseases, 2010, 4 (8), pp.e793. ⟨10.1371/journal.pntd.0000793⟩

Article dans une revue hal-02544359v1

Intravenous immunoglobulin increases survival time in the acute phase of experimental Chagas disease

B. Olivieri , R. Vasconcellos , A. Nóbrega , Paola Minoprio , S. Kaveri et al.

Parasite Immunology, 2010, 32 (6), pp.464-469. ⟨10.1111/j.1365-3024.2010.01212.x⟩

Article dans une revue pasteur-04628919v1
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Inhibition of Trypanosoma cruzi proline racemase affects host-parasite interactions and the outcome of in vitro infection

Leticia Coutinho , Marcelo Alves Ferreira , Alain Cosson , Marcos Meuser Batista , Denise da Gama Jaén Batista et al.

Memórias do Instituto Oswaldo Cruz, 2009, 104 (8), pp.1055-1062. ⟨10.1590/s0074-02762009000800001⟩

Article dans une revue pasteur-04628922v1
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Proline racemases: insights into Trypanosoma cruzi peptides containing D-proline

Nicolas Coatnoan , Armand Berneman , Nathalie Chamond , Paola Minoprio

Memórias do Instituto Oswaldo Cruz, 2009, 104 (suppl 1), pp.295-300. ⟨10.1590/s0074-02762009000900039⟩

Article dans une revue hal-02544244v1

Proline racemases are conserved mitogens: characterization of a Trypanosoma vivax proline racemase

Nathalie Chamond , Alain Cosson , Nicolas Coatnoan , Paola Minoprio

Molecular and Biochemical Parasitology, 2009, 165 (2), pp.170-179. ⟨10.1016/j.molbiopara.2009.02.002⟩

Article dans une revue istex hal-02544235v1

Crystal structure, catalytic mechanism, and mitogenic properties of Trypanosoma cruzi proline racemase

Alejandro Buschiazzo , Maira Goytia , Francis Schaeffer , Wim M. Degrave , William Shepard et al.

Proceedings of the National Academy of Sciences of the United States of America, 2006, 103 (6), pp.1705-1710. ⟨10.1073/pnas.0509010103⟩

Article dans une revue hal-02523212v1

Trypanosoma cruzi proline racemases are involved in parasite differentiation and infectivity.

Nathalie Chamond , Maira Goytia , Nicolas Coatnoan , Jean Christophe Barale , Alain Cosson et al.

Molecular Microbiology, 2005, 58 (1), pp.46-60. ⟨10.1111/j.1365-2958.2005.04808.x⟩

Article dans une revue hal-00126978v1

Biochemical Characterization of Proline Racemases from the Human Protozoan Parasite Trypanosoma cruzi and Definition of Putative Protein Signatures

Nathalie Chamond , Christophe Grégoire , Nicolas Coatnoan , Catherine Rougeot , Lucio H Freitas-Junior et al.

Journal of Biological Chemistry, 2003, 278 (18), pp.15484-15494. ⟨10.1074/jbc.m210830200⟩

Article dans une revue hal-02523188v1

Intranasal Inoculation of Bordetella Bronchiseptica in Mice Induces Long‐Lasting Antibody and T‐Cell Mediated Immune Responses

P. Gueirard , Paola Minoprio , N. Guiso

Scandinavian Journal of Immunology, 2003, 43 (2), pp.181-192. ⟨10.1046/j.1365-3083.1996.d01-30.x⟩

Article dans une revue pasteur-04628998v1

Ig‐Isotype Patterns of Primary and Secondary B Cell Responses to Plasmodium Chabaudi Chabaudi Correlate with IFN‐γ and IL‐4 Cytokine Production and with CD45RB Expression by CD4 + Spleen Cells

M. d'Império Lima , J. Alvarez , G. Furtado , T. Kipnis , A. Coutinho et al.

Scandinavian Journal of Immunology, 2003, 43 (3), pp.263-270. ⟨10.1046/j.1365-3083.1996.d01-35.x⟩

Article dans une revue pasteur-04628995v1

Increased Trypanosoma cruzi Invasion and Heart Fibrosis Associated with High Transforming Growth Factor β Levels in Mice Deficient in α 2 -Macroglobulin

M. Waghabi , C. Coutinho , M. Soeiro , M. Pereira , J.-J. Feige et al.

Infection and Immunity, 2002, 70 (9), pp.5115-5123. ⟨10.1128/iai.70.9.5115-5123.2002⟩

Article dans une revue pasteur-04628935v1

A Trypanosoma cruzi Alkaline Antigen Induces Polyclonal B‐Cell Activation of Normal Murine Spleen Cells by T‐Cell‐Independent, BCR‐Directed Stimulation

C. L. Montes , E. Zuñiga , Paola Minoprio , E. Vottero-Cima , A. Gruppi

Scandinavian Journal of Immunology, 2002, 50 (2), pp.159-166. ⟨10.1046/j.1365-3083.1999.00577.x⟩

Article dans une revue pasteur-04628967v1

Parasite polyclonal activators: new targets for vaccination approaches?

Paola Minoprio

International Journal for Parasitology, 2001, 31 (5-6), pp.588-591. ⟨10.1016/s0020-7519(01)00171-0⟩

Article dans une revue istex pasteur-04628945v1

Significant association between the skewed natural antibody repertoire ofXid mice and resistance toTrypanosoma cruzi infection

Eduardo-César Santos-Lima , Rita Vasconcellos , Bernardo Reina-San-Martín , Constantin Fesel , Anabela Cordeiro-Da-Silva et al.

European Journal of Immunology, 2001, 31 (2), pp.634-645. ⟨10.1002/1521-4141(200102)31:2<634::aid-immu634>3.0.co;2-h⟩

Article dans une revue pasteur-04628949v1

A 24,000 MW Trypanosoma cruzi antigen is a B‐cell activator

A. Cordeiro da Silva , A. Espinoza , A. Ouaissi , Paola Minoprio

Immunology, 2001, 94 (2), pp.189-196. ⟨10.1046/j.1365-2567.1998.00498.x⟩

Article dans une revue pasteur-04628978v1

Lymphocyte Polyclonal Activation: A Pitfall for Vaccine Design against Infectious Agents

B Reina-San-Martı́n , A Cosson , Paola Minoprio

Parasitology Today, 2000, 16 (2), pp.62-67. ⟨10.1016/s0169-4758(99)01591-4⟩

Article dans une revue istex pasteur-04628952v1

Changes in the cytokine profile of lupus-prone mice (NZB/NZW)F1 induced by Plasmodium chabaudi and their implications in the reversal of clinical symptoms

M Sato , Paola Minoprio , S Avrameas , T Ternynck

Clinical and Experimental Immunology, 2000, 119 (2), pp.333-339. ⟨10.1046/j.1365-2249.2000.01124.x⟩

Article dans une revue pasteur-04628958v1

Theileria annulata in CD5(+) macrophages and B1 B cells.

Marie-Françoise Moreau , Jean-Laurent Thibaud , Leila Ben-Miled , Marie Chaussepied , Martin Baumgartner et al.

Infection and Immunity, 1999, 67 (12), pp.6678-6682

Article dans une revue pasteur-02024445v1

X-linked immunodeficiency affects the outcome of Schistosoma mansoni infection in the murine model

Sophie Gaubert , Alexandra Viana Da Costa , Claude-Alain Maurage , Eduardo César Santos Lima , Josette Fontaine et al.

Parasite Immunology, 1999, 21 (2), pp.89. ⟨10.1046/j.1365-3024.1999.00205.x⟩

Article dans une revue pasteur-04628976v1
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Partial Protection of Mice against Trypanosoma cruzi after Immunizing with the TcY 72 Antigenic Preparation

Yara Gomes , Frederico Gc Abath , Mineo Nakazawa , Paola Minoprio , Ioannis Vouldoukis et al.

Memórias do Instituto Oswaldo Cruz, 1999, 94 (2), pp.167-172. ⟨10.1590/s0074-02761999000200007⟩

Article dans une revue pasteur-04628971v1

Evidence for a protective role of tumor necrosis factor in the acute phase of Trypanosoma cruzi infection in mice

E Lima , I Garcia , M Vicentelli , P Vassalli , Paola Minoprio

Infection and Immunity, 1997, 65 (2), pp.457-465. ⟨10.1128/iai.65.2.457-465.1997⟩

Article dans une revue pasteur-04628982v1

Chagas' disease is attenuated in mice lacking gamma delta T cells

E Santos Lima , Paola Minoprio

Infection and Immunity, 1996, 64 (1), pp.215-221. ⟨10.1128/iai.64.1.215-221.1996⟩

Article dans une revue pasteur-04629003v1

The influence of T cell subsets on Trypanosoma cruzi multiplication in different organs

Momtchilo Russo , Nancy Starobinas , Maria Cecilia Garibaldi Marcondes , Paola Minoprio , Mireille Honteyberie-Joskowicz

Immunology Letters, 1996, 49 (3), pp.163-168. ⟨10.1016/0165-2478(96)02498-4⟩

Article dans une revue istex pasteur-04628989v1

V β 6-bearing T cells are involved in resistance to Trypanosoma cruzi infection in XID mice

Anabela Cordeiro Da Silva , Eduardo Cesar Santos Lima , Marie-Heléne Vlcentelli , Paola Minoprio

International Immunology, 1996, 8 (8), pp.1213-1219. ⟨10.1093/intimm/8.8.1213⟩

Article dans une revue pasteur-04628984v1

The relative impact of bacterial virulence and host genetic background on cytokine expression during Mycobacterium avian infection of mice

AG Castro , Paola Minoprio , Rui Appelberg

Immunology, 1995, 85 (4), pp.556-561

Article dans une revue pasteur-04629020v1