ISABELLE ADER

26
Documents

Publications

Publications

Image document

Brown adipose tissue activity impacts systemic lactate clearance in male mice

Rémi Montané , Yannick Jeanson , Damien Lagarde , Spiro Khoury , Léana Porcher-Bibes et al.
The Journal of Physiology, In press, ⟨10.1113/JP288871⟩
Article dans une revue hal-05278863 v1

Identification of Functional Cellular Markers Related to Human Health, Frailty and Chronological Age

Chloé Brodeau , Camille Joly , Anaïs Chekroun , Jean Nakhle , Vincent Blase et al.
Aging Cell, 2025, ⟨10.1111/acel.70153⟩
Article dans une revue hal-05196072 v1
Image document

Brown adipose tissue activity impacts systemic lactate clearance in male mice

Rémi Montané , Yannick Jeanson , Damien Lagarde , Spiro Khoury , Léana Porcher-Bibes et al.
The Journal of Physiology, 2025, ⟨10.1113/JP288871⟩
Article dans une revue hal-05359302 v1
Image document

Integrative Multimodal Metabolomics to Early Predict Cognitive Decline Among Amyloid Positive Community-Dwelling Older Adults

Marie Tremblay-Franco , Cécile Canlet , Audrey Carrière , Jean Nakhle , Anne Galinier et al.
Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 2024, 79 (5), pp.glae077. ⟨10.1093/gerona/glae077⟩
Article dans une revue hal-04615498 v1

Periostin Plasma Levels and Changes on Physical and Cognitive Capacities in Community-Dwelling Older Adults

Juan Luis Sánchez-Sánchez , Isabelle Ader , Yannick Jeanson , Valérie Planat-Benard , Bruno Vellas et al.
Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 2023, 78 (3), pp.424-432. ⟨10.1093/gerona/glac226⟩
Article dans une revue hal-04475743 v1
Image document

Long non-coding RNA Neat1 and paraspeckle components are translational regulators in hypoxia

Anne-Claire Godet , Emilie Roussel , Florian David , Fransky Hantelys , Florent Morfoisse et al.
eLife, 2022, 11, pp.e69162. ⟨10.7554/elife.69162⟩
Article dans une revue hal-04718122 v1
Image document

Healthy Aging Biomarkers: The INSPIRE's Contribution

Isabelle Ader , L. Pénicaud , S. Andrieu , J.R. Beard , N. Davezac et al.
The Journal of Frailty & Aging, 2021, 10 (4), pp.313-319. ⟨10.14283/jfa.2021.15⟩
Article dans une revue hal-04718148 v1
Image document

The Inspire Research Initiative

Philippe Barreto de Souto , Sophie Guyonnet , Isabelle Ader , Sandrine Andrieu , Louis Casteilla et al.
The Journal of Frailty & Aging, 2021, 10 (2), pp.86-93. ⟨10.14283/jfa.2020.18⟩
Article dans une revue hal-02899807 v1
Image document

Lactate Fluxes and Plasticity of Adipose Tissues: A Redox Perspective

Damien Lagarde , Yannick Jeanson , Jean-Charles Portais , Anne Galinier , Isabelle Ader et al.
Frontiers in Physiology, 2021, 12, pp.689747. ⟨10.3389/fphys.2021.689747⟩
Article dans une revue hal-03376213 v1
Image document

Towards a Large-Scale Assessment of the Relationship Between Biological and Chronological Aging

Yohan Santin , Sébastien Lopez , Isabelle Ader , Sandrine Andrieu , Nicolas Blanchard et al.
The Journal of Frailty & Aging, 2021, 10 (2), pp.121-131. ⟨10.14283/jfa.2020.43⟩
Article dans une revue inserm-03019973 v1
Image document

Lactate fluxes mediated by the monocarboxylate transporter-1 are key determinants of the metabolic activity of beige adipocytes

Damien Lagarde , Yannick Jeanson , Corinne Barreau , Cedric Moro , Lindsay Peyriga et al.
Journal of Biological Chemistry, 2021, 296, pp.100137. ⟨10.1074/jbc.RA120.016303⟩
Article dans une revue hal-03085046 v1

The emerging roles of lactate as a redox substrate and signaling molecule in adipose tissues

Audrey Carrière , Damien Lagarde , Yannick Jeanson , Jean-Charles Portais , Anne Galinier et al.
Journal of Physiology and Biochemistry, 2020, 76 (2), pp.241-250. ⟨10.1007/s13105-019-00723-2⟩
Article dans une revue hal-03059917 v1
Image document

Human adipose stromal-vascular fraction self-organizes to form vascularized adipose tissue in 3D cultures

Sandra Muller , Isabelle Ader , Justine Creff , Hélène Leménager , Pauline Achard et al.
Scientific Reports, 2019, 9 (1), pp.7250. ⟨10.1038/s41598-019-43624-6⟩
Article dans une revue hal-02136504 v1
Image document

Vasohibin1, a new mouse cardiomyocyte IRES trans-acting factor that regulates translation in early hypoxia

Fransky Hantelys , Anne-Claire Godet , Florian David , Florence Tatin , Edith Renaud-Gabardos et al.
eLife, 2019, 8, pp.e50094. ⟨10.7554/eLife.50094⟩
Article dans une revue hal-03104359 v1
Image document

Mass Spectrometry-based Absolute Quantification of 20S Proteasome Status for Controlled Ex-vivo Expansion of Human Adipose-derived Mesenchymal Stromal/Stem Cells

Thomas Menneteau , Bertrand Fabre , Luc Garrigues , Alexandre Stella , Dusan Zivkovic et al.
Molecular and Cellular Proteomics, 2019, 18 (4), pp.744-759. ⟨10.1074/mcp.RA118.000958⟩
Article dans une revue hal-02167451 v1

Inhibition of the GTPase Rac1 Mediates the Antimigratory Effects of Metformin in Prostate Cancer Cells

B. Dirat , I. Ader , M. Golzio , F. Massa , Amel Mettouchi et al.
Molecular Cancer Therapeutics, 2015, 14 (2), pp.586-596. ⟨10.1158/1535-7163.MCT-14-0102⟩
Article dans une revue pasteur-02448789 v1

Neutralizing S1P inhibits intratumoral hypoxia, induces vascular remodelling and sensitizes to chemotherapy in prostate cancer

Isabelle Ader , Cécile Gstalder , Pierre Bouquerel , Muriel Golzio , Guillaume Andrieu et al.
Oncotarget, 2015, 6 (15), ⟨10.18632/oncotarget.3144⟩
Article dans une revue hal-01764907 v1
Image document

Metformin targets the GTPase Rac1 to inhibit prostate cancer cell migration

Béatrice Dirat , Isabelle Ader , Muriel Golzio , Amel Mettouchi , Kathiane Laurent et al.
Cancer & metabolism, 2014, 2 (Suppl 1), pp.O24
Article dans une revue inserm-00997565 v1

Osteoblast-derived sphingosine 1-phosphate to induce proliferation and confer resistance to therapeutics to bone metastasis-derived prostate cancer cells

L. Brizuela , C. Martin , P. Jeannot , I. Ader , C. Gstalder et al.
Molecular Oncology, 2014, 8 (7), pp.1181-95
Article dans une revue hal-01311018 v1

Synthesis, structures, and selective toxicity to cancer cells of gold(I) complexes involving N-heterocyclic carbene ligands

Luca Boselli , Isabelle Ader , Maëlle Carraz , Catherine Hemmert , Olivier Cuvillier et al.
European Journal of Medicinal Chemistry, 2014, 85, pp.87-94. ⟨10.1016/j.ejmech.2014.07.086⟩
Article dans une revue istex hal-02007936 v1

Sphingosine Kinase 1: A New Modulator of Hypoxia Inducible Factor 1α during Hypoxia in Human Cancer Cells

Isabelle Ader , Leyre Brizuela , Pierre Bouquerel , Bernard Malavaud , Olivier Cuvillier
Cancer Research, 2008, 68 (20), pp.8635-8642. ⟨10.1158/0008-5472.can-08-0917⟩
Article dans une revue hal-04645176 v1

Gem associates with Ezrin and acts via the Rho-GAP protein Gmip to down-regulate the Rho pathway.

Anastassia Hatzoglou , Isabelle Ader , Anne Splingard , James A. Flanders , Evelyne Saade et al.
Molecular Biology of the Cell, 2007, 18 (4), pp.1242-52. ⟨10.1091/mbc.E06-06-0510⟩
Article dans une revue hal-00319936 v1

Inhibition of human tumor cell growthin vivo by an orally bioavailable inhibitor of human farnesyltransferase, BIM-46228

Grégoire Prevost , Anne Pradines , Marie-Christine Brezak , Marie-Odile Lonchampt , Isabelle Viossat et al.
International Journal of Cancer, 2001, 91 (5), pp.718-722. ⟨10.1002/1097-0215(200002)9999:9999<::aid-ijc1104>3.0.co;2-s⟩
Article dans une revue hal-04645200 v1

The Farnesyltransferase Inhibitor FTI-277 Suppresses the 24-kDa FGF2-Induced Radioresistance in HeLa Cells Expressing Wild-Type RAS

Elizabeth Cohen-Jonathan , Christine Toulas , Isabelle Ader , Sylvia Monteil , Cuider Allal et al.
Radiation Research, 1999, 152 (4), pp.404. ⟨10.2307/3580225⟩
Article dans une revue hal-04645190 v1

PROCÉDÉ DE DÉTERMINATION DE L'ÂGE PHYSIOLOGIQUE D'UN SUJET

Louis Casteilla , Isabelle Ader , Philippe Kémoun , Julien Aligon , Paul Monsarrat et al.
France, N° de brevet: WO2023180436. 2023, https://data.inpi.fr/brevets/WO2023180436
Brevet hal-04731421 v1