Isabelle BEHM-ANSMANT

Identifiants chercheurs

IdHAL :

isabelle-behm-ansmant

ORCID :

0000-0001-8909-0660

IdRef :

160574234

Publications

Poster de conférence (7)

Long non-coding RNAs: promising therapeutic targets for inflammatory diseases? Isabelle Behm-Ansmant RNA therapeutics: from concept to clinic, Jun 2025, Worcester (USA), United States Poster de conférence hal-05407066v1
Unraveling the implication of the long non-coding RNA ANRIL in alternative splicing and its impacts on Cancer Julien Lhuillier,Christelle Aigueperse,Aymeric Sanchez,Lilia Ayadi,Charbel Alfeghalyet al. 13th SifrARN (Structure, Intégration, Fonction et Réactivité de l’ARN), Nov 2024, Lyon, France. Poster de conférence hal-05407019v1
Triplex Decoy oligonucleotides as modulators of long non-coding RNA activities. Lilia Ayadi,Aymeric Sanchez,Guillaume Grosjean,Charbel Alfeghaly,Franceline Reynaudet al. 13th SifrARN, Nov 2024, Lyon, France Poster de conférence hal-05407027v1
Role of the long non-coding RNA ANRIL in chromatin landscape regulation and its potential association with disease. Aymeric Sanchez,Julien Lhuillier,Lilia Ayadi,Charbel Alfeghaly,Wassim Rhaloussiet al. 13th SifrARN, Nov 2024, Lyon, France Poster de conférence hal-05407052v1
The lncRNA ANRIL-induced gene modulation depends on its Exon21 enriched in Transposable Elements Aymeric Sanchez,Charbel Alfeghaly,Lilia Ayadi,Wassim Rhalloussi,Quentin Thuillieret al. 12th SifrARN, Oct 2022, Bordeaux, France Poster de conférence hal-04577641v1
Molecular dissection of lncRNA activities: ANRIL as Model System Charbel Alfeghaly,Valentin Vautrot,Virginie Marchand,Yuri Motorin,Isabelle Behm-Ansmantet al. 24th Annual Meeting of the RNA society, Jun 2019, Cracovie, Poland Poster de conférence hal-02968492v1
Investigation of RNA biomarkers predictive of skin radio-induced fibrosis Liza Hettal,Cerimele Elise,Nathalie Rouard,Guillaume Vogin,Isabelle Behm-Ansmant EMBO-FEBS course on Molecular mechanisms of tissue injury, repair and fibrosis, May 2019, Spetses Island, Greece Poster de conférence hal-02968496v1

Article dans une revue (30)

Quantitative detection of 2’-O-methylated residues in non-coding RNAs using DNAzymes and quantitative RT-PCR Valentyne Lebret-Kogey,Lilia Ayadi,Sylvain Maenner,Yuri Motorin,Isabelle Behm-Ansmantet al. Biochimie, 2025, 237, pp.26-39. ⟨10.1016/j.biochi.2025.07.006⟩ Article dans une revue hal-05162861v1
Multiomic profiling of new-onset kidney function decline: insights from the STANISLAS study cohort with a 20-year follow-up Vincent Dupont,Constance Xhaard,Isabelle Behm-Ansmant,Emmanuel Bresso,Quentin Thuillieret al. Clinical Kidney Journal, 2024, 17 (8), pp.sfae224. ⟨10.1093/ckj/sfae224⟩ Article dans une revue hal-04660216v1
The Normal, the Radiosensitive, and the Ataxic in the Era of Precision Radiotherapy: A Narrative Review Sandrine Pereira,Ester Orlandi,Sophie Deneuve,Amelia Barcellini,Agnieszka Chalaszczyket al. Cancers, 2022, 14 (24), pp.6252. ⟨10.3390/cancers14246252⟩ Article dans une revue (article de synthèse) hal-03906711v1
Evaluation of a Functional Assay for Radiosensitivity in the Pediatric Prospective Cohort ARPEGE G. Vogin,S. Pereira,E. Cérimele,M. Duclos,V. Scherreret al. International Journal of Radiation Oncology, Biology, Physics, 2022, 114 (3S), pp.S159. ⟨10.1016/j.ijrobp.2022.07.646⟩ Article dans une revue hal-03875371v1
Fatty acid desaturase genetic variations and dietary omega-3 fatty acid intake associate with arterial stiffness Magnus Bäck,Constance Xhaard,Raphael Rouget,Quentin Thuillier,Oscar Plundeet al. European Heart Journal Open, 2022, pp.oeac016. ⟨10.1093/ehjopen/oeac016⟩ Article dans une revue hal-03613927v1
Impact of natriuretic peptide polymorphisms on diastolic and metabolic function in a populational cohort: insights from the STANISLAS cohort Constance Xhaard,Raphaël Rouget,Nicolas Vodovar,Edith Le Floch,Claire Dandine‐roullandet al. ESC Heart Failure, 2021, ⟨10.1002/ehf2.13674⟩ Article dans une revue hal-03414759v1
Implication of repeat insertion domains in the trans -activity of the long non-coding RNA ANRIL Charbel Alfeghaly,Aymeric Sanchez,Raphael Rouget,Quentin Thuillier,Valérie Igel-Bourguignonet al. Nucleic Acids Research, 2021, 49 (9), pp.4954-4970. ⟨10.1093/nar/gkab245⟩ Article dans une revue hal-03202552v1
Radiomics Method for the Differential Diagnosis of Radionecrosis Versus Progression after Fractionated Stereotactic Body Radiotherapy for Brain Oligometastasis Liza Hettal,Anais Stefani,Julia Salleron,Florent Courrech,Isabelle Behm-Ansmantet al. Radiation Research, 2020, 193 (5), pp.471. ⟨10.1667/RR15517.1⟩ Article dans une revue hal-02955312v1
Substructure Analyzer: A User-Friendly Workflow for Rapid Exploration and Accurate Analysis of Cellular Bodies in Fluorescence Microscopy Images Géraud Heckler,Christelle Aigueperse,Liza Hettal,Quentin Thuillier,Fabrice de Chaumontet al. Journal of visualized experiments : JoVE, 2020, 161, ⟨10.3791/60990⟩ Article dans une revue hal-02955300v1
Specific G-quadruplex ligands modulate the alternative splicing of Bcl-X Carika Weldon,Justine G Dacanay,Vijay Gokhale,Peda venkat l Boddupally,Isabelle Behm-Ansmantet al. Nucleic Acids Research, 2018, 46 (2), pp.886 - 896. ⟨10.1093/nar/gkx1122⟩ Article dans une revue hal-01738356v1
Deep Structural Analysis of RPAP3 and PIH1D1, Two Components of the HSP90 Co-chaperone R2TP Complex Julien Henri,Marie-Eve Chagot,Maxime Bourguet,Yoann Abel,Guillaume Terralet al. Structure, 2018, 26 (9), pp.1196-1209.e8. ⟨10.1016/j.str.2018.06.002⟩ Article dans une revue hal-01919243v1
Contribution of protein Gar1 to the RNA-guided and RNA-independent rRNA:Ψ-synthase activities of the archaeal Cbf5 protein Ryosuke Fujikane,Isabelle Behm-Ansmant,Anne-Sophie Tillault,Christine Loegler,Valérie Igel-Bourguignonet al. Scientific Reports, 2018, 8 (1), ⟨10.1038/s41598-018-32164-0⟩ Article dans une revue hal-01879274v2
Identification of G-quadruplexes in long functional RNAs using 7-deazaguanine RNA Carika Weldon,Isabelle Behm-Ansmant,Laurence H Hurley,Glenn A Burley,Christiane Branlantet al. Nature Chemical Biology, 2017, 13 (1), pp.18-20. ⟨10.1038/nCHeMBIO.2228⟩ Article dans une revue hal-01738347v1
MicroRNA-29b Contributes to Collagens Imbalance in Human Osteoarthritic and Dedifferentiated Articular Chondrocytes David Moulin,Veronique Salone,Meriem Koufany,Thomas Clément,Isabelle Behm-Ansmantet al. BioMed Research International , 2017, 2017, pp.1 - 12. ⟨10.1155/2017/9792512⟩ Article dans une revue hal-01704545v1
Enhanced SRSF5 Protein Expression Reinforces Lamin A mRNA Production in HeLa Cells and Fibroblasts of Progeria Patients Valentin Vautrot,Christelle Aigueperse,Florence Oillo-Blanloeil,Sebastien Hupont,James Steveninet al. Human Mutation, 2016, 37 (3), pp.280-291. ⟨10.1002/humu.22945⟩ Article dans une revue istex hal-01451666v1
Tau exon 2 responsive elements deregulated in myotonic dystrophy type I are proximal to exon 2 and synergistically regulated by MBNL1 and MBNL2 C. Carpentier,D. Ghanem,F. J. Fernandez-Gomez,F. Jumeau,J. V. Philippeet al. Biochimica et Biophysica Acta - Molecular Basis of Disease, 2014, 1842 (4), pp.654-664. ⟨10.1016/j.bbadis.2014.01.004⟩ Article dans une revue hal-01453196v1
Analysis of Exonic Regions Involved in Nuclear Localization, Splicing Activity, and Dimerization of Muscleblind-like-1 Isoforms Helene Tran,Nathalie Gourrier,Camille Lemercier-Neuillet,Claire-Marie Dhaenens,Audrey Vautrinet al. Journal of Biological Chemistry, 2011, 286 (18), pp.16435 - 16446. ⟨10.1074/jbc.M110.194928⟩ Article dans une revue hal-01738403v1
A conserved splicing mechanism of the LMNA gene controls premature aging Isabel Cristina Lopez-Mejia,Valentin Vautrot,Marion de Toledo,Isabelle Behm-Ansmant,Cyril Bourgeoiset al. Human Molecular Genetics, 2011, 20 (23), pp.4540-4555. ⟨10.1093/hmg/ddr385⟩ Article dans une revue hal-03034380v1
Use of Specific Chemical Reagents for Detection of Modified Nucleotides in RNA Isabelle Behm-Ansmant,Mark Helm,Yuri Motorin Journal of Nucleic Acids , 2011, 2011, pp.1 - 17. ⟨10.4061/2011/408053⟩ Article dans une revue hal-01738372v1
Antagonistic factors control the unproductive splicing of SC35 terminal intron Natacha Dreumont,Sara Hardy,Isabelle Behm-Ansmant,Liliane Kister,Christiane Branlantet al. Nucleic Acids Research, 2010, 38 (4), pp.1353 - 1366. ⟨10.1093/nar/gkp1086⟩ Article dans une revue hal-01738427v1
RNA Sequence and Two-dimensional Structure Features Required for Efficient Substrate Modification by the Saccharomyces cerevisiae RNA:Ψ-Synthase Pus7p Alan Urban,Isabelle Behm-Ansmant,Christiane Branlant,Yuri Motorin Journal of Biological Chemistry, 2009, 284 (9), pp.5845 - 5858. ⟨10.1074/jbc.M807986200⟩ Article dans une revue hal-01738433v1
P-Body Formation Is a Consequence, Not the Cause, of RNA-Mediated Gene Silencing Ana Eulalio,Isabelle Behm-Ansmant,Daniel Schweizer,Elisa Izaurralde Molecular and Cellular Biology, 2007, 27 (11), pp.3970-3981. ⟨10.1128/MCB.00128-07⟩ Article dans une revue hal-01738446v1
The Saccharomyces cerevisiae Pus2 protein encoded by YGL063w ORF is a mitochondrial tRNA: 27/28-synthase Isabelle Behm-Ansmant,Christiane Branlant,Yuri Motorin RNA, 2007, 13 (10), pp.1641 - 1647. ⟨10.1261/rna.605607⟩ Article dans une revue hal-01738450v1
mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes Isabelle Behm-Ansmant,Jan Rehwinkel,Tobias Doerks,Alexander Stark,Elisa Izaurralde Genes and Development, 2006, 20 (14), pp.1885 - 1898. ⟨10.1101/gad.1424106⟩ Article dans une revue hal-01738497v1
A previously unidentified activity of yeast and mouse RNA:pseudouridine synthases 1 (Pus1p) on tRNAs I. Behm-Ansmant,Séverine Massenet,Françoise Immel,Jeffrey R Patton,Yuri Motorinet al. RNA, 2006, 12 (8), pp.1583-1593. ⟨10.1261/rna.100806⟩ Article dans une revue hal-02279876v1
A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing Jan Rehwinkel,Isabelle Behm-Ansmant,David Gatfield,Elisa Izaurralde RNA, 2005, 11 (11), pp.1640-1647. ⟨10.1261/rna.2191905⟩ Article dans une revue hal-01738499v1
Pseudouridylation at Position 32 of Mitochondrial and Cytoplasmic tRNAs Requires Two Distinct Enzymes in Saccharomyces cerevisiae Isabelle Behm-Ansmant,Henri H. Grosjean,Séverine Massenet,Yuri Motorin,Christiane Branlant Journal of Biological Chemistry, 2004, 279 (51), pp.52998-53006. ⟨10.1074/jbc.M409581200⟩ Article dans une revue hal-01738505v1
Identification and Characterization of the tRNA:Ψ 31 -Synthase (Pus6p) of Saccharomyces cerevisiae Isabelle Ansmant,Yuri Motorin,Séverine Massenet,Henri Grosjean,Christiane Branlant Journal of Biological Chemistry, 2001, 276 (37), pp.34934-34940. ⟨10.1074/jbc.M103131200⟩ Article dans une revue hal-02279866v1
Identification of the Saccharomyces cerevisiae RNA:pseudouridine synthase responsible for formation of 2819 in 21S mitochondrial ribosomal RNA I. Ansmant,S. Massenet,H. Grosjean,Y. Motorin,C. Branlant Nucleic Acids Research, 2000, 28 (9), pp.1941-1946. ⟨10.1093/nar/28.9.1941⟩ Article dans une revue hal-02279850v1
The first determination of pseudouridine residues in 23S ribosomal RNA from hyperthermophilic Archaea Sulfolobus acidocaldarius Séverine Massenet,Isabelle Ansmant,Yuri Motorin,Christiane Branlant FEBS Letters, 1999, 462 (1-2), pp.94-100. ⟨10.1016/s0014-5793(99)01524-0⟩ Article dans une revue istex hal-02279844v1

Brevet (2)

Isolated double stranded DNA polynucleotide Sylvain Maenner,Isabelle Behm-Ansmant,Charbel Alfeghaly France, Patent n° : US2024102009A1. 2024 Brevet hal-04739312v1
Methods for determining individual radiosensitivity Isabelle Behm-Ansmant,Guillaume Vogin,Liza Hettal France, Patent n° : WO2024161024A1. 2024 Brevet hal-04739276v1

Chapitre d'ouvrage (7)

Fluorescence In Situ Hybridization of Small Non-Coding RNAs Valentin Vautrot,Géraud Heckler,Christelle Aigueperse,Isabelle Behm-Ansmant Small Non-Coding RNAs: Methods and Protocols, pp.73-85, 2021, ⟨10.1007/978-1-0716-1386-3_8⟩ Chapitre d'ouvrage hal-03201498v1
Microarray Analysis of Whole-Transcriptome RNAs Including Non-Coding RNAs Quentin Thuillier,Isabelle Behm-Ansmant Small Non-Coding RNAs: Methods and Protocols, 2300, pp.143-164, 2021, ⟨10.1007/978-1-0716-1386-3_14⟩ Chapitre d'ouvrage hal-03201496v1
Non-Coding RNA Silencing in Mammalian Cells by Antisense LNA GapmeRs Transfection Charbel Alfeghaly,Christelle Aigueperse,Sylvain Maenner,Isabelle Behm-Ansmant Small Non-Coding RNAs: Methods and Protocols, 2300, pp.31-37, 2021, ⟨10.1007/978-1-0716-1386-3_4⟩ Chapitre d'ouvrage hal-03201499v1
Study of Genome-Wide Occupancy of Long Non-Coding RNAs Using Chromatin Isolation by RNA Purification (ChIRP) Charbel Alfeghaly,Isabelle Behm-Ansmant,Sylvain Maenner Small Non-Coding RNAs: Methods and Protocols, 2300, pp.107-117, 2021, ⟨10.1007/978-1-0716-1386-3_11⟩ Chapitre d'ouvrage hal-03201497v1
Enhanced Probe-Based RT-qPCR Quantification of MicroRNAs Using Poly(A) Tailing and 5′ Adaptor Ligation Valentin Vautrot,Isabelle Behm-Ansmant Methods in Molecular Biology, 2065, pp.39-54, 2020, ⟨10.1007/978-1-4939-9833-3_4⟩ Chapitre d'ouvrage hal-02517653v1
Fluorescence In Situ Hybridization of Small Non-Coding RNAs Valentin Vautrot,Christelle Aigueperse,Christiane Branlant,Isabelle Behm-Ansmant Small Non-Coding RNAs: Methods and Protocols, 1296, Springer New York, pp.73-83, 2015, Methods in Molecular Biology, ⟨10.1007/978-1-4939-2547-6_8⟩ Chapitre d'ouvrage hal-05443390v1
Study of RNA-Protein Interactions and RNA Structure in Ribonucleoprotein Particles (RNPs) Virginie Marchand,Annie Mougin,Agnès Méreau,Isabelle Behm-Ansmant,Yuri Motorinet al. Roland K. Hartmann; Albrecht Bindereif; Astrid Schön; Eric Westhof. Handbook of RNA Biochemistry: Second, Completely Revised and Enlarged Edition, Wiley-VCH Verlag GmbH & Co. KGaA, pp.975-1016, 2014, 9783527327645. ⟨10.1002/9783527647064.ch44⟩ Chapitre d'ouvrage hal-01957954v1

Communication dans un congrès (13)

Molecular dissection of lncRNA activities: ANRIL as Model System Charbel Alfeghaly,Valentin Vautrot,Virginie Marchand,Yuri Motorin,Isabelle Behm-Ansmantet al. Bermuda Principles: Impact on Splicing 3rd Annual Conference, Feb 2019, Southampton, Bermuda Communication dans un congrès hal-02968414v1
Molecular dissection of lncRNA activities: ANRIL as Model System Charbel Alfeghaly,Valentin Vautrot,Virginie Marchand,Yuri Motorin,Isabelle Behm-Ansmantet al. 11th sifrARN, Nov 2018, Vandoeuvre-les-Nancy, France Communication dans un congrès hal-02968425v1
Changes of phosphorylation drive alternative splicing modulation by mild heat shock in human cells Christelle Aigueperse,Valentin Vautrot,Luisa Vigevani,Papasaikas Panegiotis,Nathalie Nicotet al. 11th sifrARN, Nov 2018, Vandoeuvre-les-Nancy, France Communication dans un congrès hal-02968400v1
Impact of culture conditions on the behavior of mesenchymal stem cells: choosing critical parameters related to cell quality Naceur Charif,Meriem El Ouafy,Laurie Targa,Xing Liu,Audrey Fortunat Zeh Eto'Oet al. 8th InternationalSymposium China-Europe Stem cells and regenerative medicine, Jun 2018, Wuhan, China Communication dans un congrès hal-02973631v1
Changes of SF3B1 phosphorylation status participate to alternative splicing modulation by mild heat shock Christelle Aigueperse,Valentin Vautrot,Luisa Vigevani,Papasaikas Panegiotis,Nathalie Nicotet al. Bermuda Principles: Impact on Splicing 2nd Annual Conference, Feb 2018, Southampton, Bermuda Communication dans un congrès hal-02968429v1
Crystal structure of the RPAP3-PIH1D1 cochaperones complex and regulation of the R2TP-Hsp90 machinery during macromolecular complex assembly Julien Henri,Marie-Eve Chagot,Christelle Aigueperse,Florian Georgescauld,Rénette Saint-Fortet al. The 9th International Conference on the Hsp90 Chaperone Machine, Oct 2018, Leysin, Switzerland Communication dans un congrès hal-04342574v1
SR and hnRNP proteins regulate HIV-1 multiplication by modulating mRNA splicing and translation Lilia Ayadi,Georges Khoury,Jean-Michel Saliou,Sarah Cianferani-Sanglier,Alain Vandorsselaeret al. 22nd Annual Meeting of the RNA Society, May 2017, Prague, Czech Republic Communication dans un congrès hal-02968438v1
Towards the understanding of the mechanisms responsible for alternative splicing modulation by mild heat shock Christelle Aigueperse,Valentin Vautrot,Luisa Vigevani,Papasaikas Panegiotis,Nathalie Nicotet al. 9th Bordeaux RNA Club symposium, Jun 2017, Bordeaux, France Communication dans un congrès hal-02968433v1
RNA as MCS aging biomarkers : pertinence for regenerative medicine N Charif,,Yy Li,,T Kaoma,,L Vallar,,Yp Li,et al. 6th International Symposium Europe-China, Jul 2016, Nancy, France Communication dans un congrès hal-01722952v1
Non-coding RNAs and mRNA splicing events as biomarkers of diseases and cell control quality tools, application to heart failure prevention Virginie Marchand,Valentin Vautrot,Gired Nicolas,Faiez Zannad,Patrick Rossignolet al. 6th International Symposium Europe-China, Jul 2016, Nancy, France Communication dans un congrès hal-02968456v1
RNM as MCS aging biomarkers : pertinence for regenerative medicine Naceur Charif,Li, Yy,T Kaoma,,Vallar, L,Li, Ypet al. 6th International Symposium Europe-China, Jul 2016, Nancy, France Communication dans un congrès hal-03033120v1
SR and hnRNP proteins regulate HIV-1 multiplication by modulating mRNA splicing and translation Lilia Ayadi,Georges Khoury,Jean-Michel Saliou,Sarah Cianferani-Sanglier,Alain Vandorsselaeret al. 4th Post-EURASNET Meeting, Sep 2016, Poznan, Poland Communication dans un congrès hal-02968442v1
Specific G-quadruplex ligands regulate the alternative splicing of Bcl-x Carika Weldon,Isabelle Behm-Ansmant,M. Vogler,Vijay Gokhale,Glenn A Burleyet al. 21st Annual Meeting of the RNA Society, Jun 2016, Kyoto, Japan Communication dans un congrès hal-02968462v1

HDR (1)

Régulation post-transcriptionnelle de l'expression des gènes par épissage alternatif et action des miRNA Isabelle Behm-Ansmant Biologie moléculaire. Université de Lorraine (Nancy), 2016 HDR tel-02968488v1