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Marine Invertebrates: A Promissory Still Unexplored Source of Inhibitors of Biomedically Relevant Metallo Aminopeptidases Belonging to the M1 and M17 Families
Isel Pascual
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Fabiola Almeida García
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Mario Ernesto Valdés Tresano
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Yarini Arrebola Sánchez
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Daniel Ojeda del Sol
Journal articles
hal-04085369v1
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Marine gregarine genomes reveal the breadth of apicomplexan diversity with a partially conserved glideosome machinery
Julie Boisard
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Evelyne Duvernois-Berthet
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Linda Duval
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Joseph Schrével
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Laure Guillou
Journal articles
hal-03862695v1
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Genome Sequence and Assessment of Safety and Potential Probiotic Traits of Lactobacillus johnsonii CNCM I-4884
Anne-Sophie Boucard
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Isabelle Florent
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Bruno Polack
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Philippe Langella
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Luis Bermúdez-Humarán
Journal articles
hal-03880814v1
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Parasitic Protists: Diversity of Adaptations to a Parasitic Lifestyle
Iva Kolářová
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Isabelle Florent
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Andrea Valigurová
Journal articles
hal-03880807v1
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Programmed multiple C-H bond functionalization of the privileged 4hydroxyquinoline template
Quentin Ronzon
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Wei Zhang
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Nicolas Casaretto
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Elisabeth Mouray
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Isabelle Florent
Journal articles
hal-03256641v1
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Structure-activity relationship and molecular modelling studies of quinazolinedione derivatives MMV665916 as potential antimalarial agent
Laura Mourot
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Marjorie Schmitt
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Elisabeth Mouray
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Martin Spichty
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Isabelle Florent
Journal articles
hal-03432154v1
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Nutrient Acquisition and Attachment Strategies in Basal Lineages: A Tough Nut to Crack in the Evolutionary Puzzle of Apicomplexa
Andrea Valigurová
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Isabelle Florent
Journal articles
hal-03881552v1
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Age and Giardia intestinalis Infection Impact Canine Gut Microbiota
Anne-Sophie Boucard
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Myriam Thomas
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Wilfried Lebon
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Bruno Polack
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Isabelle Florent
Journal articles
hal-03881565v1
|
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Rapid protein evolution, organellar reductions, and invasive intronic elements in the marine aerobic parasite dinoflagellate Amoebophrya spp
Sarah Farhat
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Phuong Le
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Ehsan Kayal
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Benjamin Noel
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Estelle Bigeard
Journal articles
hal-03114990v1
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Integrative taxonomy confirms that Gregarina garnhami and G. acridiorum (Apicomplexa, Gregarinidae), parasites of Schistocerca gregaria and Locusta migratoria (Insecta, Orthoptera), are distinct species
Isabelle Florent
,
Marie Pierre Chapuis
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Amandine Labat
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Julie Boisard
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Nicolas Leménager
Journal articles
hal-03150621v1
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IgG antibody response against Plasmodium falciparum aminopeptidase 1 antigen in Gabonese children living in Makokou and Franceville
S. Oyegue‐liabagui
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R.‐k. Imboumy‐limoukou
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C. Kouna
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F. Bangueboussa
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Marjorie Schmitt
Journal articles
hal-02498387v1
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Why the –omic future of Apicomplexa should include Gregarines
Julie Boisard
,
Isabelle Florent
Journal articles
hal-02553206v1
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Marine organisms : a source of biomedically relevant metallo M1, M2 and M17 exopeptidase inhibitors
Isel Pascual Alonso
,
Laura Rivera Méndez
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Fabiola Almeida
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Mario Ernesto Valdés Tresano
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Yarini Arrebola Sánchez
REVISTA CUBANA DE CIENCIAS BIOLÓGICAS, 2020, 8 (2), pp.1-36
Journal articles
hal-02944434v1
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Aminobenzosuberone derivatives as PfA-M1 inhibitors: Molecular recognition and antiplasmodial evaluation
Emmanuel Salomon
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Marjorie Schmitt
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Elisabeth Mouray
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Alastair G Mcewen
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Lotfi Bounaadja
Journal articles
hal-02530528v1
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Biochemical evidences for M1-, M17- and M18-like aminopeptidases in marine invertebrates from Cuban coastline
Isel Pascual Alonso
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Laura Rivera Méndez
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Mario E Valdés-Tresanco
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Lotfi Bounaadja
,
Marjorie Schmitt
Journal articles
hal-02902526v1
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Comparative Time-Scale Gene Expression Analysis Highlights the Infection Processes of Two Amoebophrya Strains
Sarah Farhat
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Isabelle Florent
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Benjamin Noël
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Ehsan Kayal
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Corinne da Silva
Journal articles
hal-02126891v1
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Aminobenzosuberone Scaffold as a Modular Chemical Tool for the Inhibition of Therapeutically Relevant M1 Aminopeptidases
Emmanuel Salomon
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Marjorie Schmitt
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Anil Kumar Marapaka
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Athanasios Stamogiannos
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Germain Revelant
Journal articles
hal-02128705v1
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Metallopeptidases of Toxoplasma gondii : in silico identification and gene expression
Sandie Escotte-Binet
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Antoine Huguenin
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Laurence Voutquenne-Nazabadioko
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Anne-Pascaline Martin
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Matthieu Kaltenbach
Journal articles
hal-03110320v1
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Bile Salt Hydrolase Activities: A Novel Target to Screen Anti-Giardia Lactobacilli?
Thibault Allain
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Soraya Chaouch
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Myriam Thomas
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Marie-Agnès Travers
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Isabelle Valle
Journal articles
hal-02126886v1
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Bile-Salt-Hydrolases from the Probiotic Strain Lactobacillus johnsonii La1 Mediate Anti-giardial Activity in Vitro and in Vivo
Thibault Allain
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Soraya Chaouch
,
Myriam Thomas
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Isabelle Vallée
,
André Buret
Journal articles
hal-02126890v1
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Discovery of novel non-competitive inhibitors of mammalian neutral M1 aminopeptidase (APN)
Isel Pascual
,
Pedro Valiente
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Gabriela Garcia
,
Mario Valdés-Tresanco
,
Yarini Arrebola
Journal articles
hal-02126895v1
|
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Aqueous extracts of marine invertebrates from Cuba coastline display neutral aminopeptidase inhibitory activities and effects on cancer cells and Plasmodium falciparum parasites
Isel Pascual Alonso
,
L Bounaadja
,
L Sánchez
,
L Rivera
,
Celine Tarnus
Indian Journal of Natural Products and Resources, 2017, 8 (2), pp.107-119
Journal articles
hal-02154722v1
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Selective inhibition of PfA-M1, over PfA-M17, by an amino-benzosuberone derivative blocks malaria parasites development in vitro and in vivo
Lotfi Bounaadja
,
Marjorie Schmitt
,
Sébastien Albrecht
,
Elisabeth Mouray
,
Céline Tarnus
Journal articles
hal-02126893v1
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KBE009: An antimalarial bestatin-like inhibitor of the Plasmodium falciparum M1 aminopeptidase discovered in an Ugi multicomponent reaction-derived peptidomimetic library
Jorge Gonzales-Bazerio
,
Sarah El Chamy Maluf
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Yanira Méndez
,
Isel Pascual
,
Isabelle Florent
Journal articles
hal-02134397v1
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Ultrastructure of Selenidium pendula, the Type Species of Archigregarines, and Phylogenetic Relations to Other Marine Apicomplexa
Joseph Schrével
,
Andrea Valigurová
,
Gérard Prensier
,
Aurélie Chambouvet
,
Isabelle Florent
Journal articles
hal-01338422v1
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Immunoglobulin response to the low polymorphic Pf113 antigen in children from Lastoursville, South-East of Gabon
Roméo Karl Imboumy-Limoukou
,
Sidney Maghendi-Nzondo
,
Charlene Lady Kouna
,
Lotfi Bounaadja
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Sophie Mbang
Journal articles
hal-01998452v1
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Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond
Wesley van Voorhis
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John Adams
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Roberto Adelfio
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Vida Ahyong
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Myles Akabas
Journal articles
hal-02905407v1
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Redescription of Dicyemennea eledones (Wagener, 1857) (Phylum Dicyemida) from Eledone cirrhosa (Lamarck, 1798) (Mollusca: Cephalopoda: Octopoda)
Dhikra Souidenne
,
Isabelle Florent
,
Marc Dellinger
,
Mohamed Salah Romdhane
,
Philippe Grellier
Journal articles
hal-02134414v1
|
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Diversity of apostome ciliates, Chromidina spp. (Oligohymenophorea, Opalinopsidae), parasites of cephalopods of the Mediterranean Sea
Dhikra Souidenne
,
Isabelle Florent
,
Marc Dellinger
,
Jean Lou Justine
,
Mohamed Salah Romdhane
Journal articles
hal-01368204v1
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Deconjugated bile salts produced by extracellular bile-salt hydrolase-like activities from the probiotic Lactobacillus johnsonii La1 inhibit Giardia duodenalis in vitro growth
Marie-Agnès Travers
,
Cissé Sow
,
Séverine Zirah
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Christiane Deregnaucourt
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Soraya Chaouch
Journal articles
hal-02637819v1
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Comparative antibody responses against three antimalarial vaccine candidate antigens from urban and rural exposed individuals in Gabon
Roméo-Karl Imboumy-Limoukou
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Sandrine Lydie Oyegue-Liabagui
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Stella Ndidi
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Irène Pegha-Moukandja
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Charlene Lady Kouna
Journal articles
hal-02134412v1
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A new lactobacilli in vivo expression system for the production and delivery of heterologous proteins at mucosal surfaces
Thibault Allain
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Nahla M Mansour
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May M. A. Bahr
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Rebeca Martín
,
Isabelle Florent
Journal articles
hal-02634544v1
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Access to New Endoperoxide Derivatives by Electrochemical Oxidation of Substituted 3-Azabicyclo[4.1.0]hept-4-enes
Frédérick Nuter
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Abdou Khadre Djily Dimé
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Cheng Chen
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Lotfi Bounaadja
,
Elisabeth Mouray
Journal articles
hal-01178411v1
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Genetic impairment of parasite myosin motors uncovers the contribution of host cell membrane dynamics to Toxoplasma invasion forces
Marion Bichet
,
Bastien Touquet
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Virginie Gonzalez
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Isabelle Florent
,
Markus Meissner
Journal articles
inserm-01394800v1
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Identification of divergent protein domains by combining HMM-HMM comparisons and co-occurrence detection
Amel Ghouila
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Isabelle Florent
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Fatma Zahra Guerfali
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Nicolas Terrapon
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Dhafer Laouini
Journal articles
pasteur-01060276v1
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Cycloartane triterpenes from the leaves of Neoboutonia macrocalyx L.
Jane Namukobe
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Bernard T Kiremire
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Robert Byamukama
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John M Kasenene
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Vincent Dumontet
Journal articles
hal-01005175v1
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Diversity and biological activities of the bacterial community associated with the marine sponge Phorbas tenacior (Porifera, Demospongiae).
S Dupont
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Alyssa Carré-Mlouka
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F Descarrega
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Alexander Ereskovsky
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A Longeon
Journal articles
hal-01456679v1
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Antimalarial screening via large-scale purification of Plasmodium falciparum Ca 2+ -ATPase 6 and in vitro studies
Stéphanie David-Bosne
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Isabelle Florent
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Anne-Marie Lund- Winther
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John H. L. Hansen
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Morten Buch-Pedersen
Journal articles
mnhn-02904306v1
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Structure-activity relationships and blood distribution of antiplasmodial aminopeptidase-1 inhibitors
Rébecca F. Déprez-Poulain
,
Marion Flipo
,
Catherine Piveteau
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Florence Leroux
,
Sandrine Dassonneville
Journal articles
hal-03051765v1
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Probiotics for the Control of Parasites: An Overview
Marie-Agnès Travers
,
Isabelle Florent
,
Linda Kohl
,
Philippe Grellier
Journal articles
mnhn-02047396v1
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Aminocyclopropanes as precursors of endoperoxides with antimalarial activity
Claire Madelaine
,
Olivier Buriez
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Benoit Crousse
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Isabelle Florent
,
Philippe Grellier
Organic & Biomolecular Chemistry, 2010, 8 (24), pp.5591
Journal articles
mnhn-02047403v1
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Bioinformatic strategies to provide functional clues to the unknown genes in Plasmodium falciparum genome
Isabelle Florent
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Eric Maréchal
,
Olivier Gascuel
,
Laurent Brehelin
Journal articles
hal-02659756v1
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Plasmodium falciparum PfA-M1 aminopeptidase is trafficked via the parasitophorous vacuole and marginally delivered to the food vacuole
Omid Azimzadeh
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Cissé Sow
,
Marc Gèze
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Julius Nyalwidhe
,
Isabelle Florent
Journal articles
mnhn-02904304v1
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Assessing Functional Annotation Transfers with Inter-Species Conserved Coexpression: Application to Plasmodium Falciparum
Laurent Brehelin
,
Isabelle Florent
,
Olivier Gascuel
,
Eric Maréchal
Journal articles
lirmm-00540866v1
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A Plasmodium Falciparum FcB1-Schizont-EST Collection Providing Clues to Schizont Specific Gene Structure and Polymorphism
Isabelle Florent
,
Betina M Porcel
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Elodie Guillaume
,
Corinne da Silva
,
François Artiguenave
Journal articles
lirmm-00395282v1
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Discovery of new targets for antimalarial chemotherapy
Philippe Grellier
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Delphine Depoix
,
Joseph Schrével
,
I Florent
Journal articles
mnhn-02070082v1
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Characterization of PfDYN2, a dynamin-like protein of Plasmodium falciparum expressed in schizonts
Sébastien Charneau
,
Izabela Bastos
,
Barbara Gomes Ribeiro
,
J.M. Santana
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Philippe Grellier
Journal articles
mnhn-02070094v1
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Biochemical properties and cellular localization of Plasmodium falciparum protein disulfide isomerase
Elisabeth Mouray
,
Mireille Moutiez
,
S Girault
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Christian Sergheraert
,
I Florent
Journal articles
mnhn-02070098v1
|
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Novel Selective Inhibitors of the Zinc Plasmodial Aminopeptidase PfA-M1 as Potential Antimalarial Agents
Marion Flipo
,
Terence Beghyn
,
Virginie Leroux
,
Isabelle Florent
,
Benoit Déprez
Journal articles
mnhn-02904302v1
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Labelling of four distinct trophozoite falcipains of Plasmodium falciparum by a cystatin-derived probe
Isabelle Florent
,
Fabien Lecaille
,
Jean-Jacques Montagne
,
Francis Gauthier
,
Joseph Schrével
Journal articles
mnhn-02904301v1
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Plasmodium falciparum genes differentially expressed during merozoite morphogenesis.
I Florent
,
Sébastien Charneau
,
Philippe Grellier
Molecular and Biochemical Parasitology, 2004
Journal articles
mnhn-02070129v1
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Design, synthesis and antimalarial activity of novel, quinoline-Based, zinc metallo-aminopeptidase inhibitors
Marian Flipo
,
Isabelle Florent
,
Philippe Grellier
,
Christian Sergheraert
,
Rebecca Déprez-Poulain
Journal articles
mnhn-02867485v1
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Plasmodium falciparum proteinases: cloning of the putative gene coding for the merozoite proteinase for erythrocyte invasion (MPEI) and determination of hydrolysis sites of spectrin by Pf37 proteinase
Isabelle Florent
,
S. Le Bonniec
,
B. Carcy
,
P. Grellier
,
O. Mercereau-Puijalon
Journal articles
hal-03881542v1
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