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Isabelle Guenal

Isabelle Guénal's publications


Professor at the UVSQ/Université Paris-Saclay [Laboratory of Genetics and Biology of the Cell](, UR4589 UVSQ, 2 avenue de la Source de la Bièvre 78180 Montigny-le-Bretonneux, France


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Differential adhesion during development establishes individual neural stem cell niches and shapes adult behaviour in Drosophila

Agata Banach-Latapy , Vincent Rincheval , David Briand , Isabelle Guénal , Pauline Spéder
PLoS Biology, 2023, 21 (11), pp.e3002352. ⟨10.1371/journal.pbio.3002352⟩
Journal articles hal-04294666v1
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DREAM a little dREAM of DRM: Model organisms and conservation of DREAM-like complexes

Marion Hoareau , Aurore Rincheval-Arnold , Sébastien Gaumer , Isabelle Guénal
BioEssays, 2023, 46 (2), ⟨10.1002/bies.202300125⟩
Journal articles hal-04329736v1
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Mycobacterium abscessus Opsonization Allows an Escape from the Defensin Bactericidal Action in Drosophila

Hamadoun Touré , Nicolas Durand , Isabelle Guénal , Jean-Louis Herrmann , Fabienne Girard-Misguich
Microbiology Spectrum, 2023, 11 (4), pp.e0077723. ⟨10.1128/spectrum.00777-23⟩
Journal articles hal-04114156v2
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Mycobacterium abscessus resists the innate cellular response by surviving cell lysis of infected phagocytes

Hamadoun Touré , Lee Ann Galindo , Marion Lagune , Simon Glatigny , Robert M Waterhouse
PLoS Pathogens, 2023, 19 (3), pp.e1011257. ⟨10.1371/journal.ppat.1011257⟩
Journal articles hal-04058488v2
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A High-Throughput Search for SFXN1 Physical Partners Led to the Identification of ATAD3, HSD10 and TIM50

Nesrine Tifoun , Mourad Bekhouche , José de las Heras , Arnaud Guillaume , Sylvina Bouleau
Biology, 2022, 11 (9), pp.1298. ⟨10.3390/biology11091298⟩
Journal articles hal-03769835v1
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Mass Purification Protocol for Drosophila melanogaster Wing Imaginal Discs: An Alternative to Dissection to Obtain Large Numbers of Disc Cells

Marion Hoareau , Juliette de Noiron , Jessie Colin , Isabelle Guénal
Biology, 2022, 11 (10), pp.1384. ⟨10.3390/biology11101384⟩
Journal articles hal-03786833v1
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Keeping Cell Death Alive: An Introduction into the French Cell Death Research Network

Gabriel Ichim , Benjamin Gibert , Sahil Adriouch , Catherine Brenner , Nathalie Davoust
Biomolecules, 2022, 12 (7), pp.901. ⟨10.3390/biom12070901⟩
Journal articles hal-03711790v1
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Apoptosis quantification in tissue: development of a semiautomatic protocol and assessment of critical steps of image processing

Juliette de Noiron , Marion Hoareau , Jessie Colin , Isabelle Guénal
Biomolecules, 2021, 11 (10), pp.1523. ⟨10.3390/biom11101523⟩
Journal articles hal-03297234v2
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Lessons on SpA pathogenesis from animal models

Maxime Breban , Simon Glatigny , Bilade Cherqaoui , Marie Beaufrère , Marc Lauraine
Seminars in Immunopathology, 2021, ⟨10.1007/s00281-020-00832-x⟩
Journal articles hal-03113204v1
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HLA-B27 alters BMP/TGFβ signalling in Drosophila, revealing putative pathogenic mechanism for spondyloarthritis

Benjamin Grandon , Aurore Rincheval-Arnold , Nadège Jah , Jean-Marc Corsi , Luiza M Araujo
Annals of the Rheumatic Diseases, 2019, 78 (12), pp.1653. ⟨10.1136/annrheumdis-2019-215832⟩
Journal articles hal-02975533v1
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Evolutionary conservation of Notch signaling inhibition by TMEM131L overexpression

Sebastien Szuplewski , Nesrine Maharzi , Elisabeth Nelson , Kutaiba Alhaj Hussen , Bernard Mignotte
Biochemical and Biophysical Research Communications, 2017, ⟨10.1016/j.bbrc.2017.03.123⟩
Journal articles hal-02975504v1
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Two different specific JNK activators are required to trigger apoptosis or compensatory proliferation in response to Rbf1 in Drosophila

Amandine Clavier , Aurore Rincheval-Arnold , Adrienne Baillet , Bernard Mignotte , Isabelle Guenal
Journal articles hal-02975507v1
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Le come-back de la mitochondrie dans l'apoptose chez la drosophile

Amandine Clavier , Aurore Rincheval-Arnold , Bernard Mignotte , Isabelle Guénal
Médecine/Sciences, 2016, ⟨10.1051/medsci/20163205014⟩
Journal articles hal-02975517v1
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Apoptosis in Drosophila: which role for mitochondria?

Amandine Clavier , Aurore Rincheval-Arnold , Jessie Colin , Bernard Mignotte , Isabelle Guénal
Journal articles hal-02975495v1
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The Drosophila retinoblastoma protein, Rbf1, induces a Debcl-and Drp1-dependent mitochondrial apoptosis

Amandine Clavier , Vincent Ruby , Aurore Rincheval-Arnold , Bernard Mignotte , Isabelle Guenal
Journal of Cell Science, 2015, 128, pp.3239-3249. ⟨10.1242/jcs.169896⟩
Journal articles hal-02975515v1
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Screening of suppressors of bax-induced cell death identifies glycerophosphate oxidase-1 as a mediator of debcl-induced apoptosis in Drosophila

Jessie Colin , Julie Garibal , Amandine Clavier , Sébastien Szuplewski , Yanick Risler
Genes and Cancer, 2015, 6, ⟨10.18632/genesandcancer.68⟩
Journal articles hal-02975511v1
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The pro-apoptotic activity of Drosophila Rbf1 involves dE2F2-dependent downregulation of diap1 and buffy mRNA

A Clavier , A Baillet , A Rincheval-Arnold , A Coléno-Costes , C Lasbleiz
Cell Death and Disease, 2014, 5, pp.e1405. ⟨10.1038/cddis.2014.372⟩
Journal articles hal-01311569v1
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The drosophila Bcl-2 family protein Debcl is targeted to the proteasome by the b-TrCP homologue slimb

Jessie Colin , Julie Garibal , Amandine Clavier , Aurore Rincheval-Arnold , Sébastien Gaumer
Apoptosis, 2014, 19 (10), pp.1444-1456. ⟨10.1007/s10495-014-1034-8⟩
Journal articles hal-02977706v1
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Mutating RBF Can Enhance Its Pro-Apoptotic Activity and Uncovers a New Role in Tissue Homeostasis

Cecile Milet , Aurore Rincheval-Arnold , Amandine Clavier , Alexandrine Garrigue , Bernard Mignotte
Journal articles hal-02977729v1
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The Drosophila retinoblastoma protein induces apoptosis in proliferating but not in post-mitotic cells

Cecile Milet , Aurore Rincheval-Arnold , Bernard Mignotte , Isabelle Guenal
Cell Cycle, 2010, 9 (1), pp.97-103. ⟨10.4161/cc.9.1.10251⟩
Journal articles hal-02977719v1
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The mitochondrial TOM complex modulates Bax-induced apoptosis in Drosophila

J. Colin , J. Garibal , B. Mignotte , I. Guenal
Biochemical and Biophysical Research Communications, 2009, 379, pp.939-943. ⟨10.1016/j.bbrc.2008.12.176⟩
Journal articles hal-00422234v1
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Mitochondria, Bcl-2 family proteins and apoptosomes: of worms, flies and men

Jessie Colin , Sebastien Gaumer , Isabelle Guenal , Bernard Mignotte
Frontiers in bioscience : a journal and virtual library, 2009, S1 (14), pp.290-300. ⟨10.2741/3517⟩
Journal articles hal-00354315v1

The myb related gene stonewall induces both hyperplasia and cell death in Drosophila: rescue of fly lethality by coexpression of apoptosis inducers

S. Brun , Aurore Rincheval-Arnold , Jessie Colin , Yanick Risler , Bernard Mignotte
Cell Death and Differentiation, 2006, 13, pp.1752-1762
Journal articles hal-00101292v1
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L'apoptose chez la drosophile : conservation et originalité

Sébastien Gaumer , Isabelle Guenal , Sylvain Brun , Bernard Mignotte
Médecine/Sciences, 2002
Journal articles hal-03002807v1
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reaper and bax initiate two different apoptotic pathways affecting mitochondria and antagonized by bcl-2 in Drosophila

Sylvain Brun , Vincent Rincheval , Sebastien Gaumer , Bernard Mignotte , Isabelle Guenal
Journal articles hal-03002816v1
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Bcl-2 and Bax mammalian regulators of apoptosis are functional in Drosophila

S Gaumer , I Guenal , S Brun , L Theodore , Bernard Mignotte
Cell Death and Differentiation, 2000, 7, pp.804-814. ⟨10.1038/sj.cdd.4400714⟩
Journal articles hal-03034620v2

SV40 Large T Antigen Expression Driven by col2a1 Regulatory Sequences Immortalizes Articular Chondrocytes but Does Not Allow Stabilization of Type II Collagen Expression

Nathalie Steimberg , Say Viengchareun , Florence Biehlmann , Isabelle Guénal , Bernard Mignotte
Experimental Cell Research, 1998, 249, pp.248-259
Journal articles hal-03036458v1
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Down-regulation of actin genes precedes microfilament network disruption and actin cleavage during p53 mediated-apoptosis

Isabelle Guenal , Yanick Risler , Bernard Mignotte
Journal of Cell Science, 1997
Journal articles hal-03036445v1

Bcl-2 and Hsp27 act at different levels to suppress programmed cell death

Isabelle Guenal , Carole Sidoti-de Fraisse , Sebastien Gaumer , Bernard Mignotte
Oncogene, 1997, 15 (3), pp.347-360. ⟨10.1038/sj.onc.1201182⟩
Journal articles hal-03036419v1

The three dominant female-sterile mutations of the Drosophila ovo gene are point mutations that create new translation-initiator AUG codons

M. Mevel Ninio , E. Fouilloux , Isabelle Guénal , Alain Vincent
Development (Cambridge, England), 1996
Journal articles hal-03037426v1
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Studies of specific gene induction during apoptosis of cell lines conditionally immortalized by SV40

Isabelle Guénal , Bernard Mignotte
FEBS Letters, 1995
Journal articles hal-03038620v2

Production of dominant female sterility in Drosophila melanogaster by insertion of the ovoD1 allele on autosomes: use of transformed strains to generate germline mosaics

Maryvonne Mével-Ninio , Isabelle Guénal , Bernadette Limbourg-Bouchon
Mechanisms of Development, 1994, 45 (2), pp.155-162. ⟨10.1016/0925-4773(94)90029-9⟩
Journal articles hal-03037502v1
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Apoptosis: the fly point of view

Bernard Mignotte , Jessie Colin , Sylvain Brun , Isabelle Guénal
A.I. Scovassi. Apoptosis, Research Signpost, pp.69-186, 2005, 81-308-0021-7
Book sections hal-03381529v1
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Apoptose, sénescence cellulaire, vieillissement et mitochondries

Bernard Mignotte , Isabelle Guénal , Patrice X Petit , Jean-Luc Vayssière
L'année Gérontologique 1995 (Facts And Research In Gerontology), Serdi Ed, 1995
Book sections hal-03721681v1

Interconnexion between mitophagy and mitochondrial apoptosis

Mélanie Fages , Mégane Brusson , Christine Wintz , Aurore Rincheval-Arnold , Sylvina Bouleau
Congrés MeetOchondrie, May 2022, Cap Ferret, France
Conference papers hal-04570243v1
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Spondyloarthritis etiology, pathogenesis and animal models FRI0353 Misregulation of BMP/TGFβ sheds light on the pathogenicity of HLA-B27 in spondyloarthritis

Benjamin Grandon , Aurore Rincheval , Nadège Jah , Jean-Marc Corsi , Luiza Araujo
Annual European Congress of Rheumatology, EULAR 2019, Madrid, 12–15 June 2019, Jun 2019, Madrid, Spain. pp.859, ⟨10.1136/annrheumdis-2019-eular.3344⟩
Conference papers hal-04416962v1

Drosophila model of HLA-B27 pathogenicity study.

Sébastien Gaumer , Benjamin Grandon , Aurore Rincheval-Arnold , Nadège Jah , Jean-Marc Corsi
International Genetics of Ankylosing Spondylitis Consortium Conference, Sep 2019, Versailles, France
Conference papers hal-04570222v1

Quantification de la morphologie mitochondriale dans le disque d'aile de drosophile : recherche du bon outil

Juliette Bertheault de Noiron , Vincent Rincheval , Aurore Rincheval-Arnold , Isabelle Guénal
Journée MeetOchondrie, Sep 2019, Paris, France
Conference papers hal-04570219v1

Drosophila uncovers a mechanism linking HLA-B27 to spondylathritis

Sébastien Gaumer , Benjamin Grandon , Aurore Rincheval-Arnold , Nadège Jah , Jean-Marc Corsi
Journée des drosophilistes d'Ile-de-France 2019, Jun 2019, Paris, France
Conference papers hal-04570234v1

Is fruit fly relevant to SpA?

Sébastien Gaumer , Benjamin Grandon , Aurore Rincheval-Arnold , Nadège Jah , Jean-Marc Corsi
Eleventh International Congress on Spondyloarthritides, Oct 2018, Gent, Belgium. pp.693
Conference papers hal-04444000v1

Is fruitfly relevant to HLA class I associated diseases? The example of Spa

Isabelle Guénal , Benjamin Grandon , Aurore Rincheval-Arnold , Nadège Jah , Jean-Marc Corsi
Workshop on HLA class I opathies. Clinicians meet biologists, Jun 2018, Amsterdan, Netherlands
Conference papers hal-04570214v1

02.22 Taking fly for understanding the molecular role of HLA-b27/hβ2m in spondyloarthritis

Nadège Jah , Benjamin Grandon , Aurore Rincheval-Arnold , Isabelle Guénal , Sébastien Gaumer
37th European Workshop for Rheumatology Research, Mar 2017, Athens, Greece. pp.A17
Conference papers hal-04444083v1
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Taking Fly for Understanding the Molecular Role of HLAB27/hB2m in Spondyloarthritis

Nadège Jah , Benjamin Grandon , Aurore Rincheval-Arnold , Isabelle Guénal , Sébastien Gaumer
2016 ACR/ARHP Annual Meeting, Nov 2016, Washigton, D.C., France
Conference papers hal-04443729v1
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HLA-B27/hβ2m Drosophila a new model to study HLA-B27 implication in spondyloarthritis

Nadège Jah , Benjamin Grandon , Aurore Rincheval-Arnold , Isabelle Guénal , Sébastien Gaumer
Tenth International Congress on Spondyloarthritides, Sep 2016, Gent, Belgium. pp.742-743
Conference papers hal-04443952v1