Isabelle Guenal

Isabelle Guénal's publications

Documents

Presentation

Publications

	TGFβ signaling pathway is altered by HLA-B27 expression, resulting in pathogenic consequences relevant for spondyloarthritis Marc Lauraine , Maxence de Taffin de Tilques , Dganit Melamed-Kadosh , Bilade Cherqaoui , Vincent Rincheval Arthritis Research and Therapy, 2024, 26 (131), pp.131. ⟨10.1186/s13075-024-03370-1⟩ Journal articles hal-04362225v2
	DREAM a little dREAM of DRM: Model organisms and conservation of DREAM-like complexes Marion Hoareau , Aurore Rincheval-Arnold , Sébastien Gaumer , Isabelle Guénal BioEssays, 2023, 46 (2), ⟨10.1002/bies.202300125⟩ Journal articles hal-04329736v1
	Mycobacterium abscessus Opsonization Allows an Escape from the Defensin Bactericidal Action in Drosophila Hamadoun Touré , Nicolas Durand , Isabelle Guénal , Jean-Louis Herrmann , Fabienne Girard-Misguich Microbiology Spectrum, 2023, 11 (4), pp.e0077723. ⟨10.1128/spectrum.00777-23⟩ Journal articles hal-04114156v2
	Mycobacterium abscessus resists the innate cellular response by surviving cell lysis of infected phagocytes Hamadoun Touré , Lee Ann Galindo , Marion Lagune , Simon Glatigny , Robert M Waterhouse PLoS Pathogens, 2023, 19 (3), pp.e1011257. ⟨10.1371/journal.ppat.1011257⟩ Journal articles hal-04058488v2
	Differential adhesion during development establishes individual neural stem cell niches and shapes adult behaviour in Drosophila Agata Banach-Latapy , Vincent Rincheval , David Briand , Isabelle Guénal , Pauline Spéder PLoS Biology, 2023, 21 (11), pp.e3002352. ⟨10.1371/journal.pbio.3002352⟩ Journal articles hal-04294666v1
	Mass Purification Protocol for Drosophila melanogaster Wing Imaginal Discs: An Alternative to Dissection to Obtain Large Numbers of Disc Cells Marion Hoareau , Juliette de Noiron , Jessie Colin , Isabelle Guénal Biology, 2022, 11 (10), pp.1384. ⟨10.3390/biology11101384⟩ Journal articles hal-03786833v1
	A High-Throughput Search for SFXN1 Physical Partners Led to the Identification of ATAD3, HSD10 and TIM50 Nesrine Tifoun , Mourad Bekhouche , José de las Heras , Arnaud Guillaume , Sylvina Bouleau Biology, 2022, 11 (9), pp.1298. ⟨10.3390/biology11091298⟩ Journal articles hal-03769835v1
	Keeping Cell Death Alive: An Introduction into the French Cell Death Research Network Gabriel Ichim , Benjamin Gibert , Sahil Adriouch , Catherine Brenner , Nathalie Davoust Biomolecules, 2022, 12 (7), pp.901. ⟨10.3390/biom12070901⟩ Journal articles hal-03711790v1
	Lessons on SpA pathogenesis from animal models Maxime Breban , Simon Glatigny , Bilade Cherqaoui , Marie Beaufrère , Marc Lauraine Seminars in Immunopathology, 2021, ⟨10.1007/s00281-020-00832-x⟩ Journal articles hal-03113204v1
	Apoptosis quantification in tissue: development of a semiautomatic protocol and assessment of critical steps of image processing Juliette de Noiron , Marion Hoareau , Jessie Colin , Isabelle Guénal Biomolecules, 2021, 11 (10), pp.1523. ⟨10.3390/biom11101523⟩ Journal articles hal-03297234v2
	HLA-B27 alters BMP/TGFβ signalling in Drosophila, revealing putative pathogenic mechanism for spondyloarthritis Benjamin Grandon , Aurore Rincheval-Arnold , Nadège Jah , Jean-Marc Corsi , Luiza M Araujo Annals of the Rheumatic Diseases, 2019, 78 (12), pp.1653. ⟨10.1136/annrheumdis-2019-215832⟩ Journal articles hal-02975533v1
	Evolutionary conservation of Notch signaling inhibition by TMEM131L overexpression Sebastien Szuplewski , Nesrine Maharzi , Elisabeth Nelson , Kutaiba Alhaj Hussen , Bernard Mignotte Biochemical and Biophysical Research Communications, 2017, ⟨10.1016/j.bbrc.2017.03.123⟩ Journal articles hal-02975504v1
	Two different specific JNK activators are required to trigger apoptosis or compensatory proliferation in response to Rbf1 in Drosophila Amandine Clavier , Aurore Rincheval-Arnold , Adrienne Baillet , Bernard Mignotte , Isabelle Guenal Cell Cycle, 2016, ⟨10.1080/15384101.2015.1100776⟩ Journal articles hal-02975507v1
	Le come-back de la mitochondrie dans l'apoptose chez la drosophile Amandine Clavier , Aurore Rincheval-Arnold , Bernard Mignotte , Isabelle Guénal Médecine/Sciences, 2016, ⟨10.1051/medsci/20163205014⟩ Journal articles hal-02975517v1
	Apoptosis in Drosophila: which role for mitochondria? Amandine Clavier , Aurore Rincheval-Arnold , Jessie Colin , Bernard Mignotte , Isabelle Guénal Apoptosis, 2016, ⟨10.1007/s10495-015-1209-y⟩ Journal articles hal-02975495v1
	The Drosophila retinoblastoma protein, Rbf1, induces a Debcl-and Drp1-dependent mitochondrial apoptosis Amandine Clavier , Vincent Ruby , Aurore Rincheval-Arnold , Bernard Mignotte , Isabelle Guenal Journal of Cell Science, 2015, 128, pp.3239-3249. ⟨10.1242/jcs.169896⟩ Journal articles hal-02975515v1
	Screening of suppressors of bax-induced cell death identifies glycerophosphate oxidase-1 as a mediator of debcl-induced apoptosis in Drosophila Jessie Colin , Julie Garibal , Amandine Clavier , Sébastien Szuplewski , Yanick Risler Genes and Cancer, 2015, 6, ⟨10.18632/genesandcancer.68⟩ Journal articles hal-02975511v1
	Mutating RBF Can Enhance Its Pro-Apoptotic Activity and Uncovers a New Role in Tissue Homeostasis Cecile Milet , Aurore Rincheval-Arnold , Amandine Clavier , Alexandrine Garrigue , Bernard Mignotte PLoS ONE, 2014, ⟨10.1371/journal.pone.0102902⟩ Journal articles hal-02977729v1
	The drosophila Bcl-2 family protein Debcl is targeted to the proteasome by the b-TrCP homologue slimb Jessie Colin , Julie Garibal , Amandine Clavier , Aurore Rincheval-Arnold , Sébastien Gaumer Apoptosis, 2014, 19 (10), pp.1444-1456. ⟨10.1007/s10495-014-1034-8⟩ Journal articles hal-02977706v1
	The pro-apoptotic activity of Drosophila Rbf1 involves dE2F2-dependent downregulation of diap1 and buffy mRNA A Clavier , A Baillet , A Rincheval-Arnold , A Coléno-Costes , C Lasbleiz Cell Death and Disease, 2014, 5, pp.e1405. ⟨10.1038/cddis.2014.372⟩ Journal articles hal-01311569v1
	The Drosophila retinoblastoma protein induces apoptosis in proliferating but not in post-mitotic cells Cecile Milet , Aurore Rincheval-Arnold , Bernard Mignotte , Isabelle Guenal Cell Cycle, 2010, 9 (1), pp.97-103. ⟨10.4161/cc.9.1.10251⟩ Journal articles hal-02977719v1
	The mitochondrial TOM complex modulates Bax-induced apoptosis in Drosophila J. Colin , J. Garibal , B. Mignotte , I. Guenal Biochemical and Biophysical Research Communications, 2009, 379, pp.939-943. ⟨10.1016/j.bbrc.2008.12.176⟩ Journal articles hal-00422234v1
	Mitochondria, Bcl-2 family proteins and apoptosomes: of worms, flies and men Jessie Colin , Sebastien Gaumer , Isabelle Guenal , Bernard Mignotte Frontiers in bioscience : a journal and virtual library, 2009, S1 (14), pp.290-300. ⟨10.2741/3517⟩ Journal articles hal-00354315v1
	The myb related gene stonewall induces both hyperplasia and cell death in Drosophila: rescue of fly lethality by coexpression of apoptosis inducers S. Brun , Aurore Rincheval-Arnold , Jessie Colin , Yanick Risler , Bernard Mignotte Cell Death and Differentiation, 2006, 13, pp.1752-1762 Journal articles hal-00101292v1
	L'apoptose chez la drosophile : conservation et originalité Sébastien Gaumer , Isabelle Guenal , Sylvain Brun , Bernard Mignotte Médecine/Sciences, 2002 Journal articles hal-03002807v1
	reaper and bax initiate two different apoptotic pathways affecting mitochondria and antagonized by bcl-2 in Drosophila Sylvain Brun , Vincent Rincheval , Sebastien Gaumer , Bernard Mignotte , Isabelle Guenal Oncogene, 2002, ⟨10.1038/sj.onc.1205839⟩ Journal articles hal-03002816v1
	Bcl-2 and Bax mammalian regulators of apoptosis are functional in Drosophila S Gaumer , I Guenal , S Brun , Laurent Theodore , Bernard Mignotte Cell Death and Differentiation, 2000, 7 (9), pp.804-814. ⟨10.1038/sj.cdd.4400714⟩ Journal articles hal-03034620v2
	SV40 Large T Antigen Expression Driven by col2a1 Regulatory Sequences Immortalizes Articular Chondrocytes but Does Not Allow Stabilization of Type II Collagen Expression Nathalie Steimberg , Say Viengchareun , Florence Biehlmann , Isabelle Guénal , Bernard Mignotte Experimental Cell Research, 1998, 249, pp.248-259 Journal articles hal-03036458v1
	Bcl-2 and Hsp27 act at different levels to suppress programmed cell death Isabelle Guenal , Carole Sidoti-de Fraisse , Sebastien Gaumer , Bernard Mignotte Oncogene, 1997, 15 (3), pp.347-360. ⟨10.1038/sj.onc.1201182⟩ Journal articles hal-03036419v1
	Down-regulation of actin genes precedes microfilament network disruption and actin cleavage during p53 mediated-apoptosis Isabelle Guenal , Yanick Risler , Bernard Mignotte Journal of Cell Science, 1997 Journal articles hal-03036445v1
	The three dominant female-sterile mutations of the Drosophila ovo gene are point mutations that create new translation-initiator AUG codons M. Mevel Ninio , E. Fouilloux , Isabelle Guénal , Alain Vincent Development (Cambridge, England), 1996 Journal articles hal-03037426v1
	Studies of specific gene induction during apoptosis of cell lines conditionally immortalized by SV40 Isabelle Guénal , Bernard Mignotte FEBS Letters, 1995 Journal articles hal-03038620v2
	Production of dominant female sterility in Drosophila melanogaster by insertion of the ovoD1 allele on autosomes: use of transformed strains to generate germline mosaics Maryvonne Mével-Ninio , Isabelle Guénal , Bernadette Limbourg-Bouchon Mechanisms of Development, 1994, 45 (2), pp.155-162. ⟨10.1016/0925-4773(94)90029-9⟩ Journal articles hal-03037502v1

	PINK1 and BNIP3 mitophagy inducers have an antagonistic effect on Rbf1-induced apoptosis in Drosophila Mélanie Fages , Vincent Ruby , Mégane Brusson , Aurore Rincheval-Arnold , Christine Wintz 2023 Preprints, Working Papers, ... hal-04334989v2
	A corset of adhesions during development establishes individual neural stem cell niches and controls adult behaviour Agata Banach-Latapy , Vincent Rincheval , David Briand , Isabelle Guénal , Pauline Spéder 2022 Preprints, Working Papers, ... hal-04416889v1

	Apoptosis: the fly point of view Bernard Mignotte , Jessie Colin , Sylvain Brun , Isabelle Guénal A.I. Scovassi. Apoptosis, Research Signpost, pp.69-186, 2005, 81-308-0021-7 Book sections hal-03381529v1
	Apoptose, sénescence cellulaire, vieillissement et mitochondries Bernard Mignotte , Isabelle Guénal , Patrice X Petit , Jean-Luc Vayssière L'année Gérontologique 1995 (Facts And Research In Gerontology), Serdi Ed, 1995 Book sections hal-03721681v1

	Interconnexion between mitophagy and mitochondrial apoptosis Mélanie Fages , Mégane Brusson , Christine Wintz , Aurore Rincheval-Arnold , Sylvina Bouleau Congrés MeetOchondrie, May 2022, Cap Ferret, France Conference papers hal-04570243v1
	Drosophila uncovers a mechanism linking HLA-B27 to spondylathritis Sébastien Gaumer , Benjamin Grandon , Aurore Rincheval-Arnold , Nadège Jah , Jean-Marc Corsi Journée des drosophilistes d'Ile-de-France 2019, Jun 2019, Paris, France Conference papers hal-04570234v1
	Quantification de la morphologie mitochondriale dans le disque d'aile de drosophile : recherche du bon outil Juliette Bertheault de Noiron , Vincent Rincheval , Aurore Rincheval-Arnold , Isabelle Guénal Journée MeetOchondrie, Sep 2019, Paris, France Conference papers hal-04570219v1
	Drosophila model of HLA-B27 pathogenicity study. Sébastien Gaumer , Benjamin Grandon , Aurore Rincheval-Arnold , Nadège Jah , Jean-Marc Corsi International Genetics of Ankylosing Spondylitis Consortium Conference, Sep 2019, Versailles, France Conference papers hal-04570222v1
	Spondyloarthritis etiology, pathogenesis and animal models FRI0353 Misregulation of BMP/TGFβ sheds light on the pathogenicity of HLA-B27 in spondyloarthritis Benjamin Grandon , Aurore Rincheval , Nadège Jah , Jean-Marc Corsi , Luiza Araujo Annual European Congress of Rheumatology, EULAR 2019, Madrid, 12–15 June 2019, Jun 2019, Madrid, Spain. pp.859, ⟨10.1136/annrheumdis-2019-eular.3344⟩ Conference papers hal-04416962v1
	Is fruit fly relevant to SpA? Sébastien Gaumer , Benjamin Grandon , Aurore Rincheval-Arnold , Nadège Jah , Jean-Marc Corsi Eleventh International Congress on Spondyloarthritides, Oct 2018, Gent, Belgium. pp.693 Conference papers hal-04444000v1
	Is fruitfly relevant to HLA class I associated diseases? The example of Spa Isabelle Guénal , Benjamin Grandon , Aurore Rincheval-Arnold , Nadège Jah , Jean-Marc Corsi Workshop on HLA class I opathies. Clinicians meet biologists, Jun 2018, Amsterdan, Netherlands Conference papers hal-04570214v1
	02.22 Taking fly for understanding the molecular role of HLA-b27/hβ2m in spondyloarthritis Nadège Jah , Benjamin Grandon , Aurore Rincheval-Arnold , Isabelle Guénal , Sébastien Gaumer 37th European Workshop for Rheumatology Research, Mar 2017, Athens, Greece. pp.A17 Conference papers hal-04444083v1
	HLA-B27/hβ2m Drosophila a new model to study HLA-B27 implication in spondyloarthritis Nadège Jah , Benjamin Grandon , Aurore Rincheval-Arnold , Isabelle Guénal , Sébastien Gaumer Tenth International Congress on Spondyloarthritides, Sep 2016, Gent, Belgium. pp.742-743 Conference papers hal-04443952v1
	Taking Fly for Understanding the Molecular Role of HLAB27/hB2m in Spondyloarthritis Nadège Jah , Benjamin Grandon , Aurore Rincheval-Arnold , Isabelle Guénal , Sébastien Gaumer 2016 ACR/ARHP Annual Meeting, Nov 2016, Washigton, D.C., France Conference papers hal-04443729v1

Isabelle Guenal

Presentation

Publications

TGFβ signaling pathway is altered by HLA-B27 expression, resulting in pathogenic consequences relevant for spondyloarthritis

DREAM a little dREAM of DRM: Model organisms and conservation of DREAM-like complexes

Mycobacterium abscessus Opsonization Allows an Escape from the Defensin Bactericidal Action in Drosophila

Mycobacterium abscessus resists the innate cellular response by surviving cell lysis of infected phagocytes

Differential adhesion during development establishes individual neural stem cell niches and shapes adult behaviour in Drosophila

Mass Purification Protocol for Drosophila melanogaster Wing Imaginal Discs: An Alternative to Dissection to Obtain Large Numbers of Disc Cells

A High-Throughput Search for SFXN1 Physical Partners Led to the Identification of ATAD3, HSD10 and TIM50

Keeping Cell Death Alive: An Introduction into the French Cell Death Research Network

Lessons on SpA pathogenesis from animal models

Apoptosis quantification in tissue: development of a semiautomatic protocol and assessment of critical steps of image processing

HLA-B27 alters BMP/TGFβ signalling in Drosophila, revealing putative pathogenic mechanism for spondyloarthritis

Evolutionary conservation of Notch signaling inhibition by TMEM131L overexpression

Two different specific JNK activators are required to trigger apoptosis or compensatory proliferation in response to Rbf1 in Drosophila

Le come-back de la mitochondrie dans l'apoptose chez la drosophile

Apoptosis in Drosophila: which role for mitochondria?

The Drosophila retinoblastoma protein, Rbf1, induces a Debcl-and Drp1-dependent mitochondrial apoptosis

Screening of suppressors of bax-induced cell death identifies glycerophosphate oxidase-1 as a mediator of debcl-induced apoptosis in Drosophila

Mutating RBF Can Enhance Its Pro-Apoptotic Activity and Uncovers a New Role in Tissue Homeostasis

The drosophila Bcl-2 family protein Debcl is targeted to the proteasome by the b-TrCP homologue slimb

The pro-apoptotic activity of Drosophila Rbf1 involves dE2F2-dependent downregulation of diap1 and buffy mRNA

The Drosophila retinoblastoma protein induces apoptosis in proliferating but not in post-mitotic cells

The mitochondrial TOM complex modulates Bax-induced apoptosis in Drosophila

Mitochondria, Bcl-2 family proteins and apoptosomes: of worms, flies and men

The myb related gene stonewall induces both hyperplasia and cell death in Drosophila: rescue of fly lethality by coexpression of apoptosis inducers

L'apoptose chez la drosophile : conservation et originalité

reaper and bax initiate two different apoptotic pathways affecting mitochondria and antagonized by bcl-2 in Drosophila

Bcl-2 and Bax mammalian regulators of apoptosis are functional in Drosophila

SV40 Large T Antigen Expression Driven by col2a1 Regulatory Sequences Immortalizes Articular Chondrocytes but Does Not Allow Stabilization of Type II Collagen Expression

Bcl-2 and Hsp27 act at different levels to suppress programmed cell death

Down-regulation of actin genes precedes microfilament network disruption and actin cleavage during p53 mediated-apoptosis

The three dominant female-sterile mutations of the Drosophila ovo gene are point mutations that create new translation-initiator AUG codons

Studies of specific gene induction during apoptosis of cell lines conditionally immortalized by SV40

Production of dominant female sterility in Drosophila melanogaster by insertion of the ovoD1 allele on autosomes: use of transformed strains to generate germline mosaics

PINK1 and BNIP3 mitophagy inducers have an antagonistic effect on Rbf1-induced apoptosis in Drosophila

A corset of adhesions during development establishes individual neural stem cell niches and controls adult behaviour

Apoptosis: the fly point of view

Apoptose, sénescence cellulaire, vieillissement et mitochondries

Interconnexion between mitophagy and mitochondrial apoptosis

Drosophila uncovers a mechanism linking HLA-B27 to spondylathritis

Quantification de la morphologie mitochondriale dans le disque d'aile de drosophile : recherche du bon outil

Drosophila model of HLA-B27 pathogenicity study.

Spondyloarthritis etiology, pathogenesis and animal models FRI0353 Misregulation of BMP/TGFβ sheds light on the pathogenicity of HLA-B27 in spondyloarthritis

Is fruit fly relevant to SpA?

Is fruitfly relevant to HLA class I associated diseases? The example of Spa

02.22 Taking fly for understanding the molecular role of HLA-b27/hβ2m in spondyloarthritis

HLA-B27/hβ2m Drosophila a new model to study HLA-B27 implication in spondyloarthritis

Taking Fly for Understanding the Molecular Role of HLAB27/hB2m in Spondyloarthritis