Isabelle PLO

Publications

Article dans une revue (78)

JAK2 inhibition mediates clonal selection of RAS pathway mutations in myeloproliferative neoplasms Nabih Maslah,Nina Kaci,Blandine Roux,Gabriela Alexe,Raphael Marieet al. Nature Communications, 2025, 16 (1), pp.6270. ⟨10.1038/s41467-025-60884-1⟩ Article dans une revue hal-05269747v1
Dissecting JAK2V617F’s double life with and without MPL Isabelle Plo,Caroline Marty Blood, 2025, 146 (4), pp.406-408. ⟨10.1182/blood.2025029479⟩ Article dans une revue hal-05269750v1
Expanding the phenotypic and genetic landscape of congenital neutropenia through whole‐exome and genome sequencing Séverine Marti,Philippe Pellet,Blandine Beaupain,Léa Durix,Julien Burattiet al. HemaSphere, 2025, 9 (6), ⟨10.1002/hem3.70150⟩ Article dans une revue hal-05269741v1
Telomere occupancy by TRF2 is altered by KIT mutations and correlates with mastocytosis regression Julie Bruneau,Sophie Georgin-Lavialle,Sophia Ladraa,Zakia Belaid,Isabelle Ploet al. Blood Cancer Journal, 2025, 15 (1), pp.194. ⟨10.1038/s41408-025-01372-z⟩ Article dans une revue hal-05592597v1
Type 2 calreticulin mutations activate ATF6 to promote BCL-xL–mediated survival in myeloproliferative neoplasms Nicole Arellano,William Heaton,Mirielle Nauman,Abigail Runnels,Jacky Gomez-Villaet al. Blood, 2025, 146 (8), pp.971-983. ⟨10.1182/blood.2024026940⟩ Article dans une revue hal-05269739v1
Identification of Hepatic-like EPO as a Cause of Polycythemia Laurent Martin,Darko Maric,Salam Idriss,Marine Delamare,Amandine Le Royet al. New England Journal of Medicine, 2025, 392 (17), pp.1684-1697. ⟨10.1056/NEJMoa2414954⟩ Article dans une revue hal-05269737v1
Décryptage de l’histoire naturelle des néoplasmes myéloprolifératifs grâce à une approche d’arbres phylogénétiques Jackson Josil,Eva Thuillier,Laetitia Chambrun,Isabelle Plo Médecine/Sciences, 2024, 40 (2), pp.209-211. ⟨10.1051/medsci/2023213⟩ Article dans une revue hal-05269721v1
Mathematical modelling, selection and hierarchical inference to determine the minimal dose in IFNα therapy against myeloproliferative neoplasms Gurvan Hermange,William Vainchenker,Isabelle Plo,Paul-Henry Cournède Mathematical Medicine and Biology, 2024, 41 (2), pp.110-134. ⟨10.1093/imammb/dqae006⟩ Article dans une revue hal-05269717v1
Selective targeting of mutated calreticulin by the monoclonal antibody INCA033989 inhibits oncogenic function of MPN Edimara Reis,Rebecca Buonpane,Hamza Celik,Caroline Marty,Angela Leiet al. Blood, 2024, 144 (22), pp.2336-2348. ⟨10.1182/blood.2024024373⟩ Article dans une revue hal-05269715v1
Impaired fibrinolysis in JAK2V617F-related myeloproliferative neoplasms Marie-Charlotte Bourrienne,Stéphane Loyau,Dorothée Faille,Juliette Gay,Séléna Akhenaket al. Journal of Thrombosis and Haemostasis, 2024, 22 (11), pp.3199-3208. ⟨10.1016/j.jtha.2024.07.031⟩ Article dans une revue hal-05269716v1
The double-edged sword of adenosine Isabelle Plo,Iléana Antony-Debré Haematologica, 2024, 109 (1), pp.13-15. ⟨10.3324/haematol.2023.283469⟩ Article dans une revue hal-04427016v1
New approaches to standard of care in early-phase myeloproliferative neoplasms: can interferon-α alter the natural history of the disease? Florence Pasquier,Jean Pegliasco,Jean-Edouard Martin,Severine Marti,Isabelle Plo Haematologica, 2024, 110 (4), pp.850-862. ⟨10.3324/haematol.2023.283958⟩ Article dans une revue hal-05269731v1
Deregulation of the p19/CDK4/CDK6 axis in Jak2V617F megakaryocytes accelerates the development of myelofibrosis Hélène Duparc,Delphine Muller,Laure Gilles,Agathe Chédeville,Mira El Khouryet al. Leukemia, 2024, 38 (4), pp.898-902. ⟨10.1038/s41375-024-02170-5⟩ Article dans une revue hal-04785472v1
When monoclonal gammopathy‐associated chronic neutrophilic leukemia is a reactive process distinct from a clonal myeloproliferative neoplasm: Lessons from mistakes Christophe Willekens,Claude Chahine,Matteo Dragani,Sabine Khalife-Hachem,Camille Bigenwaldet al. eJHaem, 2023, 4 (3), pp.823-826. ⟨10.1002/jha2.713⟩ Article dans une revue hal-04441619v1
Optimizing IFN Alpha Therapy against Myeloproliferative Neoplasms Gurvan Hermange,Paul-Henry Cournède,Isabelle Plo Journal of Pharmacology and Experimental Therapeutics, 2023, 387 (1), pp.31-43. ⟨10.1124/jpet.122.001561⟩ Article dans une revue hal-04308358v1
Targeting PP2A-dependent autophagy enhances sensitivity to ruxolitinib in JAK2V617F myeloproliferative neoplasms Charly Courdy,Loïc Platteeuw,Charlotte Ducau,Isabelle de Araujo,Emeline Boetet al. Blood Cancer Journal, 2023, 13 (1), pp.106. ⟨10.1038/s41408-023-00875-x⟩ Article dans une revue hal-04822779v1
Secreted mutant calreticulins as rogue cytokines in myeloproliferative neoplasms Christian Pecquet,Nicolas Papadopoulos,Thomas Balligand,Ilyas Chachoua,Amandine Tisserandet al. Blood, 2023, 141 (8), pp.917-929. ⟨10.1182/blood.2022016846⟩ Article dans une revue hal-04429999v1
SRSF2-P95H decreases JAK/STAT signaling in hematopoietic cells and delays myelofibrosis development in mice Christophe Willekens,Lucie Laplane,Tracy Dagher,Camelia Benlabiod,Nicolas Papadopouloset al. Leukemia, 2023, 37 (6), pp.1287-1297. ⟨10.1038/s41375-023-01878-0⟩ Article dans une revue hal-04430024v1
Modélisation mathématique de l'hématopoïèse et des hémopathies : développement, dynamique et traitement Gurvan Hermange,Paul-Henry P.-H. Cournède,Isabelle Plo Hématologie, 2022, 28 (4), pp.183-200. ⟨10.1684/hma.2022.1762⟩ Article dans une revue hal-04134893v1
An inherited gain‐of‐function risk allele in EPOR predisposes to familial JAK2 V617F myeloproliferative neoplasms Graciela Rabadan Moraes,Florence Pasquier,Christophe Marzac,Eric Deconinck,Carlotta Caterina Damantiet al. British Journal of Haematology, 2022, ⟨10.1111/bjh.18165⟩ Article dans une revue hal-03638075v1
Inferring the initiation and development of myeloproliferative neoplasms Gurvan Hermange,Alicia Rakotonirainy,Mahmoud Bentriou,Amandine Tisserand,Mira El-Khouryet al. Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (37), ⟨10.1073/pnas.2120374119⟩ Article dans une revue hal-03844872v1
Stepwise GATA1 and SMC3 mutations alter megakaryocyte differentiation in a Down syndrome leukemia model Brahim Arkoun,Elie Robert,Fabien Boudia,Stefania Mazzi,Virginie Dufouret al. The Journal of clinical investigation, 2022, 132 (14), pp.131-136. ⟨10.1172/JCI156290⟩ Article dans une revue hal-04441606v1
Altered Ca2+ Homeostasis in Red Blood Cells of Polycythemia Vera Patients Following Disturbed Organelle Sorting during Terminal Erythropoiesis Ralfs Buks,Tracy Dagher,Maria Giustin Rotordam,David Monedero Alonso,Sylvie Cochetet al. Cells, 2022, 11 (1), pp.49. ⟨10.3390/cells11010049⟩ Article dans une revue hal-03523607v1
Germline ATG2B/GSKIP-containing 14q32 duplication predisposes to early clonal hematopoiesis leading to myeloid neoplasms Jean Pegliasco,Pierre Hirsch,Christophe Marzac,Françoise Isnard,Jean-Côme Menianeet al. Leukemia, 2021, 36 (1), pp.126-137. ⟨10.1038/s41375-021-01319-w⟩ Article dans une revue hal-04441339v1
Inferring the dynamic of mutated hematopoietic stem and progenitor cells induced by IFNα in myeloproliferative neoplasms Matthieu Mosca,Gurvan Hermange,Amandine Tisserand,Robert John Noble,Christophe Marzacet al. Blood, 2021, ⟨10.1182/blood.2021010986⟩ Article dans une revue hal-03452002v1
Induced Pluripotent Stem Cells Enable Disease Modeling and Drug Screening in Calreticulin del52 and ins5 Myeloproliferative Neoplasms Lise Secardin,Cintia Gomez Limia,Suzana da Silva-Benedito,Larissa Lordier,Mira El-Khouryet al. HemaSphere, 2021, 5 (7), pp.e593. ⟨10.1097/HS9.0000000000000593⟩ Article dans une revue hal-03263690v1
Identification of biallelic germline variants of SRP68 in a sporadic case with severe congenital neutropenia Barbara Schmaltz-Panneau,Anne Pagnier,Séverine Clauin,Julien Buratti,Caroline Martyet al. Haematologica, 2021, 106 (4), pp.1216-1219. ⟨10.3324/haematol.2020.247825⟩ Article dans une revue hal-03243114v1
Dual role of EZH2 in megakaryocyte differentiation Stefania Mazzi,Philippe Dessen,Mathieu Vieira,Virginie Dufour,Marie Cambotet al. Blood, 2021, 138 (17), pp.1603-1614. ⟨10.1182/blood.2019004638⟩ Article dans une revue hal-03448744v1
Lyl-1 regulates primitive macrophages and microglia development Shoutang Wang,Deshan Ren,Brahim Arkoun,Anna-Lila Kaushik,Gabriel Matheratet al. Communications Biology, 2021, 4 (1), pp.1382. ⟨10.1038/s42003-021-02886-5⟩ Article dans une revue hal-04441591v1
CALR mutant protein rescues the response of MPL p.R464G variant associated with CAMT to eltrombopag Francesca Basso-Valentina,Gabriel Levy,Leila Varghese,Myriam Oufadem,Benedicte Nevenet al. Blood, 2021, 138 (6), pp.480-485. ⟨10.1182/blood.2020010567⟩ Article dans une revue hal-04429984v1
IFN: Jekyll and Hyde Isabelle Plo,William Vainchenker Blood, 2021, 137 (3), pp.291-293. ⟨10.1182/blood.2020008560⟩ Article dans une revue hal-04441320v1
PPARγ agonists promote the resolution of myelofibrosis in preclinical models Juliette Lambert,Joseph Saliba,Carolina Calderón,Karine Sii-Felice,Mohammad Salmaet al. The Journal of clinical investigation, 2021, 131 (11), ⟨10.1172/JCI136713⟩ Article dans une revue hal-04429976v1
HSPCs display within-family homogeneity in differentiation and proliferation despite population heterogeneity Tamar Tak,Giulio Prevedello,Gaël Simon,Noémie Paillon,Camélia Benlabiodet al. eLife, 2021, 10, ⟨10.7554/elife.60624⟩ Article dans une revue hal-03266494v2
Induced pluripotent stem cells and hematological malignancies: A powerful tool for disease modeling and drug development A. Donada,F. Basso-Valentina,B. Arkoun,B. Monte-Mor,Isabelle Ploet al. Stem Cell Research, 2020, 49 (2), pp.102060. ⟨10.1016/j.scr.2020.102060⟩ Article dans une revue hal-04441319v1
TET2 haploinsufficiency alters reprogramming into induced pluripotent stem cells Lise Secardin,Cintia Elisabeth Gomez Limia,Antonio Di Stefano,Martin Hernan Bonamino,Joseph Salibaet al. Stem Cell Research, 2020, 44, pp.101755. ⟨10.1016/j.scr.2020.101755⟩ Article dans une revue hal-04429959v1
Defective interaction of mutant calreticulin and SOCE in megakaryocytes from patients with myeloproliferative neoplasms Christian Di Buduo,Vittorio Abbonante,Caroline Marty,Francesco Moccia,Elisa Rumiet al. Blood, 2020, 135 (2), pp.133-144. ⟨10.1182/blood.2019001103⟩ Article dans une revue hal-04430037v1
Different impact of calreticulin mutations on human hematopoiesis in myeloproliferative neoplasms Mira El-Khoury,Xénia Cabagnols,Matthieu Mosca,Gaëlle Vertenoeil,Christophe Marzacet al. Oncogene, 2020, 39 (31), pp.5323-5337. ⟨10.1038/s41388-020-1368-3⟩ Article dans une revue hal-04429967v1
Calreticulin del52 and ins5 knock-in mice recapitulate different myeloproliferative phenotypes observed in patients with MPN Camélia Benlabiod,Maira da Costa Cacemiro,Audrey Nédélec,Valérie Edmond,Delphine Mulleret al. Nature Communications, 2020, 11 (1), pp.4886. ⟨10.1038/s41467-020-18691-3⟩ Article dans une revue hal-04429972v1
JAK2V617F myeloproliferative neoplasm eradication by a novel interferon/arsenic therapy involves PML Tracy Dagher,Nabih Maslah,Valérie Edmond,Bruno Cassinat,William Vainchenkeret al. Journal of Experimental Medicine, 2020, 218 (2), pp.e20201268. ⟨10.1084/jem.20201268⟩ Article dans une revue hal-04055414v1
Germline genetic factors in the pathogenesis of myeloproliferative neoplasms Christine Bellanné-Chantelot,Graciela Rabadan Moraes,Barbara Schmaltz-Panneau,Caroline Marty,William Vainchenkeret al. Blood Reviews, 2020, 42, pp.100710 -. ⟨10.1016/j.blre.2020.100710⟩ Article dans une revue hal-03491411v1
Surface-exposed and soluble calreticulin: conflicting biomarkers for cancer prognosis Oliver Kepp,Peng Liu,Liwei Zhao,Isabelle Plo,Guido Kroemer OncoImmunology, 2020, 9 (1), pp.5323-5337. ⟨10.1080/2162402X.2020.1792037⟩ Article dans une revue hal-04441316v1
1017 – INVESTIGATING THE MECHANISMS OF IFNALPHA THERAPY IN JAK2V617F AND CALR MUTATED MYELOPROLIFERATIVE NEOPLASMS Isabelle Plo,Amandine Tisserand,Robert Noble,Tracy Dagher,Nabih Maslahet al. Experimental Hematology, 2020, 88, pp.S22. ⟨10.1016/j.exphem.2020.09.016⟩ Article dans une revue hal-05469740v1
DNA‐bound elastase of neutrophil extracellular traps degrades plasminogen, reduces plasmin formation, and decreases fibrinolysis: proof of concept in septic shock plasma Dayana Barbosa Da Cruz,Julie Helms,Lluvia Ramírez Aquino,Laure Stiel,Lucas Cougourdanet al. FASEB Journal, 2019, Quantitative Biology, 33 (12), pp.14270-14280. ⟨10.1096/fj.201901363RRR⟩ Article dans une revue inserm-05368569v1
Impact of interferon on a triple positive polycythemia vera Hugo Campario,Matthieu Mosca,Bernard Aral,Valentin Bourgeois,Pauline Martinet al. Leukemia, 2019, 34 (4), pp.1210-1212. ⟨10.1038/s41375-019-0636-0⟩ Article dans une revue hal-04441302v1
MCM8-and MCM9 Deficiencies Cause Lifelong Increased Hematopoietic DNA Damage Driving p53- Dependent Myeloid Tumors Malik Lutzmann,Florence F. Bernex,Cindy da Costa de Jesus,Dana Hodroj,Caroline Martyet al. Cell Reports, 2019, 28 (11), pp.2851 - 2865. ⟨10.1016/j.celrep.2019.07.095⟩ Article dans une revue hal-02397140v1
Description of a knock-in mouse model of JAK2V617F MPN emerging from a minority of mutated hematopoietic stem cells Olivier Mansier,Badr Kilani,Amélie V. Guitart,Alexandre Guy,Virginie Gourdou-Latyszenoket al. Blood, 2019, 134 (26), pp.2383-2387. ⟨10.1182/blood.2019001163⟩ Article dans une revue hal-03194452v1
Disrupted filamin A/αIIbβ3 interaction induces macrothrombocytopenia by increasing RhoA activity Alessandro Donada,Nathalie Balayn,Dominika Sliwa,Larissa Lordier,Valentina Cegliaet al. Blood, 2019, 133 (16), pp.1778-1788. ⟨10.1182/blood-2018-07-861427⟩ Article dans une revue hal-04441275v1
Description of a knock-in mouse model of JAK2V617F MPN emerging from a minority of mutated hematopoietic stem cells Olivier Mansier,Badr Kilani,Amélie Guitart,Alexandre Guy,Virginie Gourdou-Latyszenoket al. Blood, 2019, 134 (26), pp.2383-2387. ⟨10.1182/blood.2019001163⟩ Article dans une revue hal-04429945v1
Not just another kinase mutation! Isabelle Plo,Caroline Marty Blood, 2019, 134 (26), pp.2335-2337. ⟨10.1182/blood.2019003650⟩ Article dans une revue hal-04430049v1
Inherited transmission of the CSF3R T618I mutational hotspot in familial chronic neutrophilic leukemia Nicolas Duployez,Christophe Willekens,Isabelle Plo,Alice Marceau-Renaut,Stéphane de Bottonet al. Blood, 2019, 134 (26), pp.2414-2416. ⟨10.1182/blood.2019003206⟩ Article dans une revue hal-04441297v1
Description of a knock-in mouse model of JAK2V617F MPN emerging from a minority of mutated hematopoietic stem cells Olivier Mansier,Badr Kilani,Amelie V Guitart,Alexandre Guy,Virginie Gourdou-Latyszenoket al. Blood, 2019, 134 (26), pp.2383-2387. ⟨10.1182/blood.2019001163⟩ Article dans une revue hal-04140431v1
Mutations in the SRP54 gene cause severe congenital neutropenia as well as Shwachman-Diamond–like syndrome Christine Bellanné-Chantelot,Barbara Schmaltz-Panneau,Caroline Marty,Odile Fenneteau,Isabelle Callebautet al. Blood, 2018, 132 (12), pp.1318-1331. ⟨10.1182/blood-2017-12-820308⟩ Article dans une revue hal-02343565v1
HSP27 is a partner of JAK2-STAT5 and a potential therapeutic target in myelofibrosis Margaux Sevin,Lucia Kubovcakova,Nicolas Pernet,Sebastien Causse,Franck Vitteet al. Nature Communications, 2018, 9 (1), pp.1431. ⟨10.1038/s41467-018-03627-9⟩ Article dans une revue hal-01864299v1
Specific and Synergistic Targeting of JAK2V617F Cells By Interferon Alpha and Arsenic Tracy Dagher,Valérie Edmond,Bruno Cassinat,Valérie Lallemand-Breitenbach,Emmanuelle Vergeret al. Blood, 2018, 132 (Supplement 1), pp.52-52. ⟨10.1182/blood-2018-99-112518⟩ Article dans une revue hal-04055417v1
New pathogenic mechanisms induced by germline erythropoietin receptor mutations in primary erythrocytosis Florence Pasquier,Caroline Marty,Thomas Balligrand,Frédérique Verdier,Sarah Grosjeanet al. Haematologica, 2017, 103 (4), pp.575-586. ⟨10.3324/haematol.2017.176370⟩ Article dans une revue hal-02403399v1
Identification of MPL R102P Mutation in Hereditary Thrombocytosis Christine Bellanne-Chantelot,Matthieu Mosca,Caroline Marty,Rémi Favier,William Vainchenkeret al. Frontiers in Endocrinology, 2017, 8, pp.235. ⟨10.3389/fendo.2017.00235⟩ Article dans une revue hal-01617931v1
Critical role of the HDAC6–cortactin axis in human megakaryocyte maturation leading to a proplatelet-formation defect Isabelle Godin,Kahia Messaoudi,Ashfaq Ali,Rameez Ishaq,Alberta Palazzoet al. Nature Communications, 2017, 8, ⟨10.1038/s41467-017-01690-2⟩ Article dans une revue hal-02992921v1
Acquired TET2 mutation in one patient with familial platelet disorder with predisposition to AML led to the development of pre-leukaemic clone resulting in T2-ALL and AML-M0 Vladimir T. Manchev,Hind Bouzid,Iléana Antony-Debré,Betty Leite,Guillaume Meuriceet al. Journal of Cellular and Molecular Medicine, 2017, 21 (6), pp.1237 - 1242. ⟨10.1111/jcmm.13051⟩ Article dans une revue hal-01537098v1
CXCL12/CXCR4 pathway is activated by oncogenic JAK2 in a PI3K-dependent manner Hadjer Abdelouahab,Yanyan Zhang,Monika Wittner,Shinya Oishi,Nobutaka Fujiiet al. Oncotarget, 2017, 8 (33), ⟨10.18632/oncotarget.10789⟩ Article dans une revue hal-02380531v1
A driver role for GABA metabolism in controlling stem and proliferative cell state through GHB production in glioma Elias A El-Habr,Gustavo Luiz Dubois,Fanny Burel-Vandenbos,Alexandra Bogeas,Joanna Lipeckaet al. Acta Neuropathologica, 2017, 133 (4), pp.645-660. ⟨10.1007/s00401-016-1659-5⟩ Article dans une revue (data paper) inserm-01481051v1
P53 activation inhibits all types of hematopoietic progenitors and all stages of megakaryopoiesis. Emna Mahfoudhi,Larissa Lordier,Caroline Marty,Jiajia Pan,Anita Royet al. Oncotarget, 2016, 7, pp.31980-92. ⟨10.18632/oncotarget.7881⟩ Article dans une revue pasteur-01467563v1
CXCR4/CXCL12 axis counteracts hematopoietic stem cell exhaustion through selective protection against oxidative stress Yanyan Zhang,Mallorie Dépond,Liang He,Adlen Foudi,Edward Owusu Kwartenget al. Scientific Reports, 2016, 6, pp.37827. ⟨10.1038/srep37827⟩ Article dans une revue inserm-01472381v1
TET2-mediated 5-hydroxymethylcytosine induces genetic instability and mutagenesis Emna Mahfoudhi,Ibtissam A Talhaoui,Xenia Cabagnols,Véronique Della Valle,Lise Secardinet al. DNA Repair, 2016, 43, pp.78 - 88. ⟨10.1016/j.dnarep.2016.05.031⟩ Article dans une revue pasteur-01405648v1
Ph− myeloproliferative neoplasm red blood cells display deregulation of IQGAP1-Rho GTPase signaling depending on CALR/JAK2 status Nuria Socoro-Yuste,Marie-Claire Dagher,Anne Gonzalez de Peredo,Julie Mondet,Affif Zaccariaet al. Biochimica et Biophysica Acta - Molecular Cell Research, 2016, 1863 (11), pp.2758 - 2765. ⟨10.1016/j.bbamcr.2016.08.012⟩ Article dans une revue hal-01400202v1
Presence of atypical thrombopoietin receptor (MPL) mutations in triple negative essential thrombocythemia patients. Xénia Cabagnols,Fabrizia Favale,Florence Pasquier,Kahia Messaoudi,Jean Philippe Defouret al. Blood, 2015, 127, pp.333-342. ⟨10.1182/blood-2015-07-661983⟩ Article dans une revue hal-01258942v1
Propriétés et rôles biologiques des protéines TET au cours du développement et de l’hématopoïèse Emna Mahfoudhi,Lise Secardin,Laurianne Scourzic,Olivier Bernard,William Vainchenkeret al. Médecine/Sciences, 2015, 31 (3), pp.268-274. ⟨10.1051/medsci/20153103012⟩ Article dans une revue pasteur-02015397v1
Level of RUNX1 activity is critical for leukemic predisposition but not for thrombocytopenia Iléana Antony-Debré,Vladimir T Manchev,Nathalie Balayn,Dominique Bluteau,Cécile Tomowiaket al. Blood, 2015, 6 (125), pp.930-940. ⟨10.1182/blood-2014-06-585513⟩ Article dans une revue hal-01681166v1
DNA binding of the p21 repressor ZBTB2 is inhibited by cytosine hydroxymethylation Céline Lafaye,Ewa Barbier,Audrey Miscioscia,Christine Saint-Pierre,Alexandra Krautet al. Biochemical and Biophysical Research Communications, 2014, 446 (1), pp.341-346 Article dans une revue hal-01994537v1
Inhibition of TET2-mediated conversion of 5-methylcytosine to 5-hydroxymethylcytosine disturbs erythroid and granulomonocytic differentiation of human hematopoietic progenitors Elodie Pronier,Carole Almire,Hayat Mokrani,Aparna Vasanthakumar,Audrey Simonet al. Blood, 2011, 118 (9), pp.2551-2555. ⟨10.1182/blood-2010-12-324707⟩ Article dans une revue hal-03390385v1
AKT1 represses gene conversion induced by different genotoxic stresses and induces supernumerary centrosomes and aneuploidy, in hamster ovary cells Isabelle Plo,Bernard S Lopez Oncogene, 2009, 28, pp.2231-2237. ⟨10.1038/onc.2009.85⟩ Article dans une revue hal-00413792v1
Role of MRE11 in chromosomal non-homologous end-joining in mammalian cells Emilie Rass,Anastazja Grabarz,Isabelle Plo,Jean Gautier,Pascale Bertrandet al. Nature Structural and Molecular Biology, 2009, 16, pp.819-824. ⟨10.1038/nsmb.1641⟩ Article dans une revue istex hal-00413788v1
Analysis of the ten-eleven translocation 2 (TET2) gene in familial myeloproliferative neoplasms. Cécile Saint-Martin,Gwendoline Leroy,François Delhommeau,Gérard Panelatti,Sabrina Dupontet al. Blood, 2009, 114 (8), pp.1628-32. ⟨10.1182/blood-2009-01-197525⟩ Article dans une revue hal-00453231v1
Defects in XRCC4 and KU80 differentially affect the joining of distal nonhomologous ends Josée Guirouilh-Barbat,Emilie Rass,Isabelle Plo,Pascale Bertrand,Bernard S. Lopez Proceedings of the National Academy of Sciences of the United States of America, 2007, 104 (52), pp.20902-20907. ⟨10.1073/pnas.0708541104⟩ Article dans une revue hal-03048190v1
Defect in XRCC4 and KU80 differentially affect the joining of distal nonhomologous ends. Josée Guirouilh-Barbat,Bernard Lopez,Pascale Bertrand,Emilie Rass,Isabelle Plo Proceedings of the National Academy of Sciences of the United States of America, 2007, 104 (52), pp.20902-20907 Article dans une revue hal-00309956v1
Apoptotic Topoisomerase I-DNA Complexes Induced by Staurosporine-mediated Oxygen Radicals Olivier Sordet,Qasim Khan,Isabelle Plo,Philippe Pourquier,Yoshimasa Urasakiet al. Journal of Biological Chemistry, 2004, 279 (48), pp.50499-50504. ⟨10.1074/jbc.M410277200⟩ Article dans une revue inserm-02438646v1
Protein kinase Cζ mediated Raf-1/extracellular-regulated kinase activation by daunorubicin Véronique Mansat-De Mas,Hélène Hernandez,Isabelle Plo,Christine Bezombes,Nicolas Maestreet al. Blood, 2003, 101 (4), pp.1543-1550. ⟨10.1182/blood-2002-05-1585⟩ Article dans une revue hal-02349095v1
Oxidative stress-induced activation of Lyn recruits sphingomyelinase and is requisite for its stimulation by Ara-C Christine Bezombes,Isabelle Plo,Véronique Mansat-de Mas,Anne Quillet-Mary,Anne Nègre-Salvayreet al. FASEB Journal, 2001, 15 (9), pp.1583-1585. ⟨10.1096/fj.00-0787fje⟩ Article dans une revue hal-02349143v1
Daunorubicin- and Mitoxantrone-Triggered Phosphatidylcholine Hydrolysis: Implication in Drug-Induced Ceramide Generation and Apoptosis Ali Bettaieb,Isabelle Plo,Véronique Mansat-de Mas,Anne Quillet-Mary,Thierry Levadeet al. Molecular Pharmacology, 1999, 55 (1), pp.118-125. ⟨10.1124/mol.55.1.118⟩ Article dans une revue hal-02349169v1

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