isabelle TRANOY

Publications

Article dans une revue (28)

An Enzyme-Responsive Imiquimod Prodrug for Precision Immune Activation within the Tumor Microenvironment Elsa Cannoni,Israa Al Jamal,Rony Eid,Rémi Châtre,Pauline Poinotet al. Bioconjugate Chemistry, 2026, 37 (1), pp.150-159. ⟨10.1021/acs.bioconjchem.5c00541⟩ Article dans une revue hal-05456767v1
β-Glucuronidase-Responsive Albumin-Binding Prodrug of Colchicine-Site Binders for Selective cancer Therapy Alexandra Bordes,Isabelle Opalinski,Fabien Thoreau,Olivier Provot,Abdallah Hamzeet al. ChemMedChem, 2025, 20 (9), pp.e202400969. ⟨10.1002/cmdc.202400969⟩ Article dans une revue hal-04918349v1
An Enzyme‐Responsive Self‐Immolative Recognition Marker for Manipulating Cell–Cell Interactions Chad Plumet,Spyridon Katsakos,Mélissa Girard,Israa Al Jamal,Jonathan Clarhautet al. Advanced Science, In press, ⟨10.1002/advs.202402278⟩ Article dans une revue hal-04641807v1
Induced-volatolomics, a new research field in chemical biology Estelle Blochouse,Rony Eid,Elsa Cannoni,Rémi Châtre,Claude Geffroyet al. Comptes Rendus. Chimie, 2024, 26 (S3), pp.1-11. ⟨10.5802/crchim.252⟩ Article dans une revue hal-04553048v1
Induced-volatolomics for the design of tumour activated therapy Rémi Châtre,Estelle Blochouse,Rony Eid,Fabiola Djago,Justin Langeet al. Chemical Science, 2023, 14 (18), pp.4697-4703. ⟨10.1039/d2sc06797h⟩ Article dans une revue hal-04098727v1
Stimuli‐Responsive Catenane‐Based Catalysts Adrien Bessaguet,Quentin Blancart-Remaury,Pauline Poinot,Isabelle Opalinski,Sébastien Papot Angewandte Chemie International Edition, 2023, 62 (6), pp.e202216787. ⟨10.1002/anie.202216787⟩ Article dans une revue hal-03919984v1
A β-Cyclodextrin-Albumin Conjugate for Enhancing Therapeutic Efficacy of Cytotoxic Drugs Chad Plumet,Rémi Châtre,Fabiola Djago,Elodie Péraudeau,Quentin Blancart-Remauryet al. Bioconjugate Chemistry, 2022, 33 (6), pp.1138-1144. ⟨10.1021/acs.bioconjchem.2c00182⟩ Article dans une revue hal-03765739v1
Absolute configuration of a [1]rotaxane determined from vibrational and electronic circular dichroism spectra Andrew R Puente,Adrien Bessaguet,Noël Pairault,Grégory Pieters,Jeanne Crassouset al. Chirality, 2021, 33 (11), pp.773-782. ⟨10.1002/chir.23365⟩ Article dans une revue hal-03360296v1
Diastereoselective synthesis of [1]rotaxanes via an active metal template strategy Noël Pairault,Adrien Bessaguet,Romain Barat,Lucas Frédéric,Grégory Pieterset al. Chemical Science, 2021, 12 (7), pp.2521-2526. ⟨10.1039/d0sc05369d⟩ Article dans une revue hal-03105942v1
The Lossen rearrangement from free hydroxamic acids Mikaël Thomas,Jérôme Alsarraf,Nahla Araji,Isabelle Tranoy-Opalinski,Brigitte Renouxet al. Organic & Biomolecular Chemistry, 2019, 17 (22), pp.5420-5427. ⟨10.1039/c9ob00789j⟩ Article dans une revue hal-02380109v1
Enhancing tumor response to targeted chemotherapy through up-regulation of folate receptor α expression induced by dexamethasone and valproic acid E. Peraudeau,L. Cronier,A. Monvoisin,P. Poinot,C. Mergaultet al. Journal of Controlled Release, 2018, 269, pp.36-44. ⟨10.1016/j.jconrel.2017.11.011⟩ Article dans une revue hal-02122599v1
Targeting the tumour microenvironment with an enzyme-responsive drug delivery system for the efficient therapy of breast and pancreatic cancers Brigitte Renoux,Florian Raes,Thibaut Legigan,Elodie Péraudeau,Balkis Eddhifet al. Chemical Science, 2017, 8 (5), pp.3427-3433. ⟨10.1039/C7SC00472A⟩ Article dans une revue hal-02174996v1
Rotaxane-based architectures for biological applications Noël Pairault,Romain Barat,I. Tranoy-Opalinski,Brigitte Renoux,Mikaël Thomaset al. Comptes Rendus. Chimie, 2016, 19 (1-2), pp.103-112. ⟨10.1016/j.crci.2015.05.012⟩ Article dans une revue hal-03127619v1
A dendritic β-galactosidase-responsive folate–monomethylauristatin E conjugate Jérôme Alsarraf,Elodie Peraudeau,Pauline Poinot,I. Tranoy-Opalinski,Jonathan Clarhautet al. Chemical Communications, 2015, 51 (87), pp.15792-15795. ⟨10.1039/C5CC05294G⟩ Article dans une revue hal-03127679v1
A mechanically interlocked molecular system programmed for the delivery of an anticancer drug Romain Barat,Thibaut Legigan,I. Tranoy-Opalinski,Brigitte Renoux,Elodie Peraudeauet al. Chemical Science, 2015, 6 (4), pp.2608-2613. ⟨10.1039/c5sc00648a⟩ Article dans une revue hal-03127729v1
beta-Glucuronidase-responsive prodrugs for selective cancer chemotherapy: An update Isabelle Tranoy-Opalinski,Thibaut Legigan,Romain Barat,Jonathan Clarhaut,Mikael Thomaset al. European Journal of Medicinal Chemistry, 2014, 74, pp.302-313. ⟨10.1016/j.ejmech2013.12.045⟩ Article dans une revue hal-01196935v1
An enzyme-responsive system programmed for the double release of bioactive molecules through an intracellular chemical amplification process M. Grinda,T. Legigan,J. Clarhaut,E. Peraudeau,I. Tranoy-Opalinskiet al. Organic & Biomolecular Chemistry, 2013, 11 (41), pp.7129-7133. ⟨10.1039/c3ob41536h⟩ Article dans une revue hal-00966980v1
A galactosidase-responsive doxorubicin-folate conjugate for selective targeting of acute myelogenous leukemia blasts Jonathan Clarhaut,Sylvain Fraineau,Joëlle Guilhot,Elodie Péraudeau,Isabelle Tranoy-Opalinskiet al. Leukemia Research, 2013, 37 (8), pp.948 - 955. ⟨10.1016/j.leukres.2013.04.026⟩ Article dans une revue istex inserm-02444614v1
Synthesis and biological evaluations of a monomethylauristatin E glucuronide prodrug for selective cancer chemotherapy Thibaut Legigan,Jonathan Clarhaut,Brigitte Renoux,Isabelle Tranoy-Opalinski,Arnaud Monvoisinet al. European Journal of Medicinal Chemistry, 2013, 67, pp.75-80. ⟨10.1016/j.ejmech.2013.06.037⟩ Article dans une revue (data paper) istex hal-04033523v1
A self-immolative dendritic glucuronide prodrug of doxorubicin Marion Grinda,J. Clarhaut,Brigitte Renoux,Isabelle Tranoy-Opalinski,Sébastien Papot MedChemComm, 2012, 3 (1), pp.68-70. ⟨10.1039/c1md00193k⟩ Article dans une revue hal-00682705v1
Synthesis and Antitumor Efficacy of a β-Glucuronidase-Responsive Albumin-Binding Prodrug of Doxorubicin. Thibaut Legigan,Jonathan Clarhaut,Brigitte Renoux,Isabelle Tranoy-Opalinski,Arnaud Monvoisinet al. Journal of Medicinal Chemistry, 2012, 55 (9), pp.4516-20. ⟨10.1021/jm300348r⟩ Article dans une revue hal-00710692v1
The First Generation of β-Galactosidase-Responsive Prodrugs Designed for the Selective Treatment of Solid Tumors in Prodrug Monotherapy Thibaut Legigan,Jonathan Clarhaut,Isabelle Tranoy-Opalinski,Arnaud Monvoisin,Brigitte Renouxet al. Angewandte Chemie International Edition, 2012, 51, pp.1 - 6. ⟨10.1002/anie.201204935⟩ Article dans une revue istex hal-00736090v1
A Heterodimeric Glucuronide Prodrug for Cancer Tritherapy: the Double Role of the Chemical Amplifier Marion Grinda,Jonathan Clarhaut,Isabelle Tranoy-Opalinski,Brigitte Renoux,Arnaud Monvoisinet al. ChemMedChem, 2011, 6 (12), pp.2137-2141. ⟨10.1002/cmdc.201100355⟩ Article dans une revue (data paper) istex hal-04033576v1
A Galactosidase‐Responsive “Trojan Horse” for the Selective Targeting of Folate Receptor‐Positive Tumor Cells Mickaël Thomas,Jonathan Clarhaut,Pierre-Olivier Strale,Isabelle Tranoy-Opalinski,Joëlle Rocheet al. ChemMedChem, 2011, 6 (6), pp.1006-1010. ⟨10.1002/cmdc.201100114⟩ Article dans une revue istex hal-05326356v1
Synthesis and biological evaluation of glucuronide prodrugs of the histone deacetylase inhibitor CI-994 for application in selective cancer chemotherapy. Mickaël Thomas,Jonathan A. Clarhaut,Isabelle Tranoy-Opalinski,Jean-Pierre Gesson,Joëlle Rocheet al. Bioorganic and Medicinal Chemistry, 2008, 16 (17), pp.8109-8116. ⟨10.1016/j.bmc.2008.07.048⟩ Article dans une revue istex hal-00458881v1
Design, synthesis and biological evaluation of 1,4-benzodiazepine-2,5-dione-based HDAC inhibitors Lynda Loudni,Joëlle Roche,Vincent Potiron,Jonathan Clarhaut,Christian Bachmannet al. Bioorganic and Medicinal Chemistry Letters, 2007, 17 (17), pp.4819-4823. ⟨10.1016/j.bmcl.2007.06.067⟩ Article dans une revue istex hal-05326359v1
Looking forward : a glance into the future of organic chemistry Philippe Compain,Valérie Desvergnes,Cyril Ollivier,Frédéric Robert,Franck Suzenetet al. New Journal of Chemistry, 2006, 30 (6), pp.823-831. ⟨10.1039/B601837H⟩ Article dans une revue istex hal-00158370v1
Future alchemy: account of the ESYOP experiment Philippe Compain,Valérie Desvergnes,Cyril Ollivier,Frédéric Robert,Franck Suzenetet al. Comptes Rendus. Chimie, 2006, 9, pp.127-140. ⟨10.1016/j.crci.2005.09.004⟩ Article dans une revue istex hal-00158010v1