Jakub Toczek Chargé de recherche, Inserm ; UMR Univ. Grenoble Alpes, Inserm U1039 – Radiopharmaceutiques Biocliniques (LRB)

Identifiants chercheurs

IdHAL :

jakub-toczek

IdRef :

202900835

VIAF :

165150565766906252786

Publications

Article dans une revue (30)

Positron Emission Tomography Imaging of Vessel Wall Matrix Metalloproteinase Activity in Abdominal Aortic Aneurysm Jakub Toczek,Kiran Gona,Yongjian Liu,Azmi Ahmad,Mean Ghimet al. Circulation: Cardiovascular Imaging, 2023, 16 (1), ⟨10.1161/CIRCIMAGING.122.014615⟩ Article dans une revue hal-04741598v1
Multimodality Imaging of Aortic Valve Calcification and Function in a Murine Model of Calcific Aortic Valve Disease and Bicuspid Aortic Valve Azmi Ahmad,Mean Ghim,Jakub Toczek,Afarin Neishabouri,Devi Ojhaet al. Journal of Nuclear Medicine, 2023, 64 (9), pp.1487-1494. ⟨10.2967/jnumed.123.265516⟩ Article dans une revue hal-04741623v1
Homeostatic, Non-Canonical Role of Macrophage Elastase in Vascular Integrity Mani Salarian,Mean Ghim,Jakub Toczek,Jinah Han,Dar Weisset al. Circulation Research, 2023, 132 (4), pp.432-448. ⟨10.1161/CIRCRESAHA.122.322096⟩ Article dans une revue hal-04741617v1
Deletion of matrix metalloproteinase-12 compromises mechanical homeostasis and leads to an aged aortic phenotype in young mice Bart Spronck,Abhay Ramachandra,Lauren Moriyama,Jakub Toczek,Jinah Hanet al. Journal of Biomechanics, 2022, 141, pp.111179. ⟨10.1016/j.jbiomech.2022.111179⟩ Article dans une revue hal-04741647v1
Differential BMP Signaling Mediates the Interplay Between Genetics and Leaflet Numbers in Aortic Valve Calcification Jae-Joon Jung,Azmi Ahmad,Saranya Rajendran,Linyan Wei,Jiasheng Zhanget al. JACC : Basic to Translational Science, 2022, 7 (4), pp.333-345. ⟨10.1016/j.jacbts.2021.12.006⟩ Article dans une revue hal-04741653v1
Considerations on PET/MR imaging of carotid plaque inflammation with 68Ga-Pentixafor Jakub Toczek,Laurent Riou Journal of Nuclear Cardiology, 2022, 29 (2), pp.503-505. ⟨10.1007/s12350-020-02354-3⟩ Article dans une revue hal-04741644v1
Targeted Suppression of miRNA-33 Using pHLIP Improves Atherosclerosis Regression Xinbo Zhang,Noemi Rotllan,Alberto Canfrán-Duque,Jonathan Sun,Jakub Toczeket al. Circulation Research, 2022, 131 (1), pp.77-90. ⟨10.1161/CIRCRESAHA.121.320296⟩ Article dans une revue hal-04741629v1
Evolution of arterial [18F]-sodium fluoride uptake and calcification Jakub Toczek Journal of Nuclear Cardiology, 2021, 28 (5), pp.1946-1948. ⟨10.1007/s12350-019-01969-5⟩ Article dans une revue hal-04741667v1
FDG PET imaging of vascular inflammation in post-traumatic stress disorder: A pilot case–control study Jakub Toczek,Ansel Hillmer,Jinah Han,Chi Liu,Dana Peterset al. Journal of Nuclear Cardiology, 2021, 28 (2), pp.688-694. ⟨10.1007/s12350-019-01724-w⟩ Article dans une revue hal-04741657v1
Computed tomography imaging of macrophage phagocytic activity in abdominal aortic aneurysm Jakub Toczek,Parnaz Boodagh,Nowshin Sanzida,Mean Ghim,Mani Salarianet al. Theranostics, 2021, 11 (12), pp.5876-5888. ⟨10.7150/thno.55106⟩ Article dans une revue hal-04741663v1
Identifying the leukocyte uptake pattern of inflammation imaging agents: Current limitations and potential impact Laurent M. Riou,Jakub Toczek,Alexis Broisat,Catherine Ghezzi,Loïc Djaileb Journal of Nuclear Cardiology, 2020, 28 (4), pp.646-1648. ⟨10.1007/s12350-019-01979-3⟩ Article dans une revue inserm-02440546v1
Accuracy of arterial [18F]-Fluorodeoxyglucose uptake quantification: A kinetic modeling study Jakub Toczek,Jing Wu,Ansel Hillmer,Jinah Han,Irina Esterliset al. Journal of Nuclear Cardiology, 2020, 27 (5), pp.1578-1581. ⟨10.1007/s12350-020-02055-x⟩ Article dans une revue hal-04741677v1
Hydroxamate-Based Selective Macrophage Elastase (MMP-12) Inhibitors and Radiotracers for Molecular Imaging Kiran Gona,Jakub Toczek,Yunpeng Ye,Nowshin Sanzida,Arvene Golbaziet al. Journal of Medicinal Chemistry, 2020, 63 (23), pp.15037-15049. ⟨10.1021/acs.jmedchem.0c01514⟩ Article dans une revue hal-03320529v1
Genetic deficiency or pharmacological inhibition of miR-33 protects from kidney fibrosis Nathan Price,Verónica Miguel,Wen Ding,Abhishek Singh,Shipra Maliket al. JCI Insight, 2019, 4 (22), pp.9743-9752. ⟨10.1172/jci.insight.131102⟩ Article dans une revue hal-04741696v1
Novel Matrix Metalloproteinase 12 Selective Radiotracers for Vascular Molecular Imaging Jakub Toczek,Thomas Bordenave,Kiran Gona,Hye-Yeong Kim,Fabrice Beauet al. Journal of Medicinal Chemistry, 2019, 62 (21), pp.9743-9752. ⟨10.1021/acs.jmedchem.9b01186⟩ Article dans une revue hal-04467935v1
Novel Arginine-containing Macrocyclic MMP Inhibitors: Synthesis, 99mTc-labeling, and Evaluation Yunpeng Ye,Jakub Toczek,Kiran Gona,Hye-Yeong Kim,Jinah Hanet al. Scientific Reports, 2018, 8 (1), pp.11647. ⟨10.1038/s41598-018-29941-2⟩ Article dans une revue hal-04741713v1
Matrix Metalloproteinase–Targeted Imaging of Lung Inflammation and Remodeling Reza Golestani,Mahmoud Razavian,Yunpeng Ye,Jiasheng Zhang,Jae-Joon Junget al. Journal of Nuclear Medicine, 2017, 58 (1), pp.138-143. ⟨10.2967/jnumed.116.176198⟩ Article dans une revue hal-04741737v1
Characterization of Macrophage Polarization States Using Combined Measurement of 2-Deoxyglucose and Glutamine Accumulation Sina Tavakoli,Kevin Downs,John Short,Huynh Nga Nguyen,Yanlai Laiet al. Arteriosclerosis, Thrombosis, and Vascular Biology, 2017, 37 (10), pp.1840-1848. ⟨10.1161/ATVBAHA.117.308848⟩ Article dans une revue hal-04741727v1
Preclinical Evaluation of RYM1, a Matrix Metalloproteinase–Targeted Tracer for Imaging Aneurysm Jakub Toczek,Yunpeng Ye,Kiran Gona,Hye-Yeong Kim,Jinah Hanet al. Journal of Nuclear Medicine, 2017, 58 (8), pp.1318-1323. ⟨10.2967/jnumed.116.188656⟩ Article dans une revue hal-04741721v1
A New Tracer for Imaging Atherosclerosis Jakub Toczek,Mehran Sadeghi Circulation: Cardiovascular Imaging, 2016, 9 (5), ⟨10.1161/CIRCIMAGING.116.004889⟩ Article dans une revue hal-04741747v1
Optical imaging of MMP-12 active form in inflammation and aneurysm Mahmoud Razavian,Thomas Bordenave,Dimitris Georgiadis,Fabrice Beau,Jiasheng Zhanget al. Scientific Reports, 2016, 6 (1), pp.38345. ⟨10.1038/srep38345⟩ Article dans une revue hal-04741787v1
Matrix metalloproteinase inhibitor, doxycycline and progression of calcific aortic valve disease in hyperlipidemic mice Jae-Joon Jung,Mahmoud Razavian,Hye-Yeong Kim,Yunpeng Ye,Reza Golestaniet al. Scientific Reports, 2016, 6 (1), pp.32659. ⟨10.1038/srep32659⟩ Article dans une revue hal-04741791v1
Molecular imaging concepts Jakub Toczek,Mehran Sadeghi Journal of Nuclear Cardiology, 2016, 23 (2), pp.271-273. ⟨10.1007/s12350-016-0403-9⟩ Article dans une revue hal-04741745v1
Novel Molecular Imaging Approaches to Abdominal Aortic Aneurysm Risk Stratification Jakub Toczek,Judith Meadows,Mehran Sadeghi Circulation: Cardiovascular Imaging, 2016, 9 (1), ⟨10.1161/CIRCIMAGING.115.003023⟩ Article dans une revue (article de synthèse) hal-04741753v1
Periaortic Brown Adipose Tissue as a Major Determinant of [18F]-Fluorodeoxyglucose Vascular Uptake in Atherosclerosis-Prone, ApoE−/− Mice Jakub Toczek,Alexis Broisat,Pascale Perret,Marie-Dominique Desruet,Daniel Fagretet al. PLoS ONE, 2014, 9 (7), pp.e99441. ⟨10.1371/journal.pone.0099441⟩ Article dans une revue hal-04660958v1
99mTc-cAbVCAM1-5 Imaging Is a Sensitive and Reproducible Tool for the Detection of Inflamed Atherosclerotic Lesions in Mice Alexis Broisat,Jakub Toczek,Laurent Dumas,Mitra Ahmadi,Sandrine Bacotet al. European Journal of Nuclear Medicine, 2014, 55 (10), pp.1678-1684. ⟨10.2967/jnumed.114.143792⟩ Article dans une revue inserm-01077899v1
Nanobody-coupled microbubbles as novel molecular tracer Sophie Hernot,Sunil Unnikrishnan,Zhongmin Du,Talent Shevchenko,Bernard Cosynset al. Journal of Controlled Release, 2012, 158 (2), pp.346-353. ⟨10.1016/j.jconrel.2011.12.007⟩ Article dans une revue hal-04742002v1
Nanobodies targeting mouse/human VCAM1 for the nuclear imaging of atherosclerotic lesions. Alexis Broisat,Sophie Hernot,Jakub Toczek,Jens de Vos,Laurent M. Riouet al. Circulation Research, 2012, 110 (7), pp.927-37. ⟨10.1161/CIRCRESAHA.112.265140⟩ Article dans une revue inserm-00831749v1
Elucidating atherosclerotic vulnerable plaque rupture by modeling cross substitution of ApoE-/- mouse and human plaque components stiffnesses. Jacques Ohayon,Nicolas Mesnier,Alexis Broisat,Jakub Toczek,Laurent Riouet al. Biomechanics and Modeling in Mechanobiology, 2012, 11 (6), pp.801-13. ⟨10.1007/s10237-011-0353-8⟩ Article dans une revue istex hal-00846364v1
Assessing low levels of mechanical stress in aortic atherosclerotic lesions from apolipoprotein E-/- mice--brief report. Alexis Broisat,Jakub Toczek,Nicolas Mesnier,Philippe Tracqui,Catherine Ghezziet al. Arteriosclerosis, Thrombosis, and Vascular Biology, 2011, 31 (5), pp.1007-10. ⟨10.1161/ATVBAHA.111.225227⟩ Article dans une revue hal-00846368v1

Thèse (1)

Caractérisation et imagerie moléculaire de la plaque d'athérome : études pré-cliniques Jakub Toczek Médecine humaine et pathologie. Université de Grenoble, 2013. Français. ⟨NNT : 2013GRENS037⟩ Thèse tel-01556490v1