jean-Christophe Andrau

Publications

Article dans une revue (48)

Targeting transcription-replication conflicts using G-quadruplexes stabilizers in multiple myeloma Laure Dutrieux,Sara Ovejero,Antoine Guillemin,Miss Leriem Zellagui,Elke de Bruyneet al. Blood Neoplasia, 2025, 2 (2), pp.100072. ⟨10.1016/j.bneo.2025.100072⟩ Article dans une revue hal-05343640v1
G-quadruplexes are promoter elements controlling nucleosome exclusion and RNA polymerase II pausing Cyril Esnault,Amal Zine El Aabidine,Marie-Cécile Robert,Anne Cucchiarini,Talha Magatet al. Nature Genetics, 2025, 57 (8), pp.1981-1993. ⟨10.1038/s41588-025-02263-6⟩ Article dans une revue hal-05337666v1
Abnormal Immune Profile in Individuals with Kabuki Syndrome Margot Comel,Norma Saad,Debapratim Sil,Florence Apparailly,Marjolaine Willemset al. Journal of Clinical Immunology, 2024, 45 (1), pp.7. ⟨10.1007/s10875-024-01796-5⟩ Article dans une revue hal-04913847v1
Comprehensive mapping of genetic variation at Epromoters reveals pleiotropic association with multiple disease traits Jing Wan,Antoinette van Ouwerkerk,Jean-Christophe Mouren,Carla Heredia,Lydie Pradelet al. Nucleic Acids Research, 2024, ⟨10.1093/nar/gkae1270⟩ Article dans une revue hal-04882272v1
G-quadruplex forming motifs in the promoter region of the B-MYB proto-oncogene André Miranda,Anne Cucchiarini,Cyril Esnault,Jean-Christophe Andrau,Paula Oliveiraet al. International Journal of Biological Macromolecules, 2024, 270, pp.132244. ⟨10.1016/j.ijbiomac.2024.132244⟩ Article dans une revue hal-04753347v1
G4access identifies G-quadruplexes and their associations with open chromatin and imprinting control regions Cyril Esnault,Talha Magat,Amal Zine El Aabidine,Encar Garcia-Oliver,Anne Cucchiariniet al. Nature Genetics, 2023, 55 (8), pp.1359-1369. ⟨10.1038/s41588-023-01437-4⟩ Article dans une revue hal-04793061v1
RNA polymerase II CTD is dispensable for transcription and required for termination in human cells Yousra Yahia,Alexia Pigeot,Amal Zine El Aabidine,Nilay Shah,Nezih Karasuet al. EMBO Reports, 2023, 24 (9), pp.e56150. ⟨10.15252/embr.202256150⟩ Article dans une revue hal-04285692v1
The control of transcriptional memory by stable mitotic bookmarking Maëlle Bellec,Jérémy Dufourt,George Hunt,Hélène Lenden-Hasse,Antonio Trulloet al. Nature Communications, 2022, 13 (1), pp.1176. ⟨10.1038/s41467-022-28855-y⟩ Article dans une revue hal-03858303v1
Notch-dependent and -independent functions of transcription factor RBPJ Tobias Friedrich,Francesca Ferrante,Léo Pioger,Andrea Nist,Thorsten Stieweet al. Nucleic Acids Research, 2022, 50 (14), pp.7925-7937. ⟨10.1093/nar/gkac601⟩ Article dans une revue hal-03852469v1
Stochastic pausing at latent HIV-1 promoters generates transcriptional bursting Katjana Tantale,Encar Garcia-Oliver,Marie-Cécile Robert,Adèle L’hostis,Yueyuxiao Yanget al. Nature Communications, 2021, 12 (1), pp.4503. ⟨10.1038/s41467-021-24462-5⟩ Article dans une revue hal-03382893v1
Fra-1 regulates its target genes via binding to remote enhancers without exerting major control on chromatin architecture in triple negative breast cancers Fabienne Bejjani,Claire Tolza,Mathias Boulanger,Damien Downes,Raphaël Romeroet al. Nucleic Acids Research, 2021, 49 (5), pp.2488-2508. ⟨10.1093/nar/gkab053⟩ Article dans une revue hal-03253453v1
GOLT1B Activation in Hepatitis C Virus-Infected Hepatocytes Links ER Trafficking and Viral Replication Jacqueline Butterworth,Damien Gregoire,Marion Peter,Armando Andres Roca Suarez,Guillaume Desandréet al. Pathogens, 2021, 11, ⟨10.3390/pathogens11010046⟩ Article dans une revue hal-03541060v1
Integration of high-throughput reporter assays identify a critical enhancer of the Ikzf1 gene Jaafar Alomairi,Anne Molitor,Nori Sadouni,Saadat Hussain,Magali Torreset al. PLoS ONE, 2020, 15 (5), pp.e0233191. ⟨10.1371/journal.pone.0233191⟩ Article dans une revue hal-02773600v1
Evaluation of DNA Methylation Episignatures for Diagnosis and Phenotype Correlations in 42 Mendelian Neurodevelopmental Disorders Erfan Aref-Eshghi,Jennifer Kerkhof,Victor Pedro,Mouna Barat-Houari,Nathalie Ruiz-Pallareset al. American Journal of Human Genetics, 2020, 106 (3), pp.356-370. ⟨10.1016/j.ajhg.2020.01.019⟩ Article dans une revue hal-02538107v1
Alternative Enhancer Usage and Targeted Polycomb Marking Hallmark Promoter Choice during T Cell Differentiation Muhammad Ahmad Maqbool,Léo Pioger,Amal Zine El Aabidine,Nezih Karasu,Anne Marie Molitoret al. Cell Reports, 2020, 32, ⟨10.1016/j.celrep.2020.108048⟩ Article dans une revue hal-03015018v1
Immunopathological manifestations in Kabuki syndrome: a registry study of 177 individuals Henri Margot,Guilaine Boursier,Claire Duflos,Elodie Sanchez,Jeanne Amielet al. Genetics in Medicine, 2020, 22 (1), pp.181-188. ⟨10.1038/s41436-019-0623-x⟩ Article dans une revue hal-02268419v1
Critical role for TRIM28 and HP1β/γ in the epigenetic control of T cell metabolic reprograming and effector differentiation Ulf Gehrmann,Marianne Burbage,Elina Zueva,Christel Goudot,Cyril Esnaultet al. Proceedings of the National Academy of Sciences of the United States of America, 2019, 116 (51), pp.25839-25849. ⟨10.1073/pnas.1901639116⟩ Article dans une revue hal-02369616v1
MIR sequences recruit zinc finger protein ZNF768 to expressed genes Michaela Rohrmoser,Michael Kluge,Yousra Yahia,Anita Gruber-Eber,Muhammad Ahmad Maqboolet al. Nucleic Acids Research, 2019, 47 (2), pp.700-715. ⟨10.1093/nar/gky1148⟩ Article dans une revue hal-04918168v1
The Landscape of L1 Retrotransposons in the Human Genome Is Shaped by Pre-insertion Sequence Biases and Post-insertion Selection Tania Sultana,Dominic van Essen,Oliver Siol,Marc Bailly-Bechet,Claude Philippeet al. Molecular Cell, 2019, 74 (3), pp.555-570.e7. ⟨10.1016/j.molcel.2019.02.036⟩ Article dans une revue hal-02401618v1
Regulation of the positive transcriptional effect of PLZF through a non-canonical EZH2 activity Myriam Koubi,Mathilde Poplineau,Julien Vernerey,Lia N 'Guyen,Guillaume Tiberiet al. Nucleic Acids Research, 2018, 46 (7), pp.3339-3350. ⟨10.1093/nar/gky080⟩ Article dans une revue hal-01765664v1
Tyrosine-1 of RNA Polymerase II CTD Controls Global Termination of Gene Transcription in Mammals. Nilay Shah,Muhammad Ahmad Maqbool,Yousra Yahia,Amal Zine El Aabidine,Cyril Esnaultet al. Molecular Cell, 2018, 69 (1), pp.48-61.e6. ⟨10.1016/j.molcel.2017.12.009⟩ Article dans une revue hal-03022268v1
ARS2 is a general suppressor of pervasive transcription Claudia Iasillo,Manfred Schmid,Yousra Yahia,Muhammad A Maqbool,Nicolas Descosteset al. Nucleic Acids Research, 2017, 45 (17), pp.10229-10241. ⟨10.1093/nar/gkx647⟩ Article dans une revue hal-02343528v1
A threshold level of NFATc1 activity facilitates thymocyte differentiation and opposes notch-driven leukaemia development I. Screpanti,E. Serfling,A. K. Patra,S. Klein-Hessling,R. Rudolfet al. Nature Communications, 2016, 7, pp.11841. ⟨10.1038/ncomms11841⟩ Article dans une revue hal-02187331v1
Lineage-specific enhancers activate self-renewal genes in macrophages and embryonic stem cells Erinn L. Soucie,Ziming Weng,Laufey Geirsdottir,Kaaweh Molawi,Julien Maurizioet al. Science, 2016, 351 (6274), pp.680-U123. ⟨10.1126/science.aad5510⟩ Article dans une revue hal-01438535v1
Dynamic recruitment of Ets1 to both nucleosome-occupied and -depleted enhancer regions mediates a transcriptional program switch during early T-cell differentiation Pierre Cauchy,Muhammad A. Maqbool,Joaquin Zacarias-Cabeza,Laurent Vanhille,Frederic Kochet al. Nucleic Acids Research, 2016, 44 (8), pp.3567-3585. ⟨10.1093/nar/gkv1475⟩ Article dans une revue hal-01438545v1
Pasha: a versatile R package for piling chromatin HTS data Romain Fenouil,Nicolas Descostes,Lionel Spinelli,Frederic Koch,Muhammad Ahmad Maqboolet al. Bioinformatics, 2016, 32 (16), pp.2528 - 2530. ⟨10.1093/bioinformatics/btw206⟩ Article dans une revue hal-01407393v1
Site- and allele-specific polycomb dysregulation in T-cell leukaemia Jean-Marc Navarro,Aurore Touzart,Lydie Pradel,Marie Loosveld,Myriam Koubiet al. Nature Communications, 2015, 6 (1), pp.6094. ⟨10.1038/ncomms7094⟩ Article dans une revue hal-01612097v1
The chromatin environment shapes DNA replication origin organization and defines origin classes Christelle Cayrou,Benoit Ballester,Isabelle Peiffer,Romain Fenouil,Philippe Coulombeet al. Genome Research, 2015, 25 (12), pp.1873-1885. ⟨10.1101/gr.192799.115⟩ Article dans une revue hal-03101863v1
Transcription-Dependent Generation of a Specialized Chromatin Structure at the TCRβ Locus Joaquin Zacarias-Cabeza,Mohamed Belhocine,Laurent Vanhille,Pierre Cauchy,Frederic Kochet al. Journal of Immunology, 2015, 194 (7), pp.3432--3443. ⟨10.4049/jimmunol.1400789⟩ Article dans une revue hal-01614946v1
High-throughput and quantitative assessment of enhancer activity in mammals by CapStarr-seq Laurent Vanhille,Aurélien Griffon,Muhammad Ahmad Maqbool,Joaquin Zacarias-Cabeza,Lan T.M. Daoet al. Nature Communications, 2015, 6, pp.6905. ⟨10.1038/ncomms7905⟩ Article dans une revue hal-01614948v1
Tyrosine phosphorylation of RNA polymerase II CTD is associated with antisense promoter transcription and active enhancers in mammalian cells Nicolas Descostes,Martin Heidemann,Lionel Spinelli,Roland Schüller,Muhammad Ahmad Maqboolet al. eLife, 2014, 3, ⟨10.7554/eLife.02105⟩ Article dans une revue hal-01431911v1
Architecture and expression of the nfatc1 gene in lymphocytes R. Rudolf,R. Busch,A. K. Patra,K. Muhammad,A. Avotset al. Frontiers in Immunology, 2014, 5, pp.21. ⟨10.3389/fimmu.2014.00021⟩ Article dans une revue hal-02191590v1
Editorial for “Diversity of the non-coding transcriptomes revealed by RNA-seq technologies” Antonin Morillon,Jean-Christophe Andrau Methods, 2013, 63 (1), pp.1-2. ⟨10.1016/j.ymeth.2013.08.030⟩ Article dans une revue istex hal-02349843v1
Divergent transcription is associated with promoters of transcriptional regulators. Cyrille Lepoivre,Mohamed Belhocine,Aurélie Bergon,Aurélien Griffon,Miriam Yammineet al. BMC Genomics, 2013, 14 (1), pp.914. ⟨10.1186/1471-2164-14-914⟩ Article dans une revue inserm-00924629v1
Editorial for &quot;Diversity of the non-coding transcriptomes revealed by RNA-seq technologies A. Morillon,J. C. Andrau Methods, 2013, 63 (1), pp.1--2. ⟨10.1016/j.ymeth.2013.08.030⟩ Article dans une revue istex hal-02191629v1
Divergent transcription is associated with promoters of transcriptional regulators C. Lepoivre,M. Belhocine,A. Bergon,A. Griffon,M. Yammineet al. BMC Genomics, 2013, 14, pp.914. ⟨10.1186/1471-2164-14-914⟩ Article dans une revue hal-02192888v1
An update on recent methods applied for deciphering the diversity of the noncoding RNA genome structure and function S. Spicuglia,M. A. Maqbool,Denis Puthier,J. C. Andrau Methods, 2013, 63 (1), pp.3--17. ⟨10.1016/j.ymeth.2013.04.003⟩ Article dans une revue hal-01595815v1
CpG islands and GC content dictate nucleosome depletion in a transcription-independent manner at mammalian promoters R. Fenouil,P. Cauchy,F. Koch,N. Descostes,J. Z. Cabezaet al. Genome Research, 2012, 22 (12), pp.2399--2408. ⟨10.1101/gr.138776.112⟩ Article dans une revue hal-01614960v1
Threonine-4 of mammalian RNA polymerase II CTD is targeted by Polo-like kinase 3 and required for transcriptional elongation C. Hintermair,M. Heidemann,F. Koch,N. Descostes,M. Gutet al. EMBO Journal, 2012, 31 (12), pp.2784--97. ⟨10.1038/emboj.2012.123⟩ Article dans une revue hal-02193058v1
Argonaute proteins couple chromatin silencing to alternative splicing Maya Ameyar-Zazoua,Christophe Rachez,Mouloud Souidi,Philippe Robin,Lauriane Fritschet al. Nature Structural and Molecular Biology, 2012, 19 (10), pp.998 - 1004. ⟨10.1038/nsmb.2373⟩ Article dans une revue istex pasteur-01393429v1
Noncoding transcription at enhancers: general principles and functional models G. Natoli,J. C. Andrau Annual Review of Genetics, 2012, 46, pp.1--19. ⟨10.1146/annurev-genet-110711-155459⟩ Article dans une revue hal-02193070v1
Splicing enhances recruitment of methyltransferase HYPB/Setd2 and methylation of histone H3 Lys36. Sérgio Fernandes de Almeida,Ana Rita Grosso,Frederic Koch,Romain Fenouil,Sílvia Carvalhoet al. Nature Structural and Molecular Biology, 2011, 18 (9), pp.977-83. ⟨10.1038/nsmb.2123⟩ Article dans une revue istex hal-00667731v1
Transcription initiation platforms and GTF recruitment at tissue-specific enhancers and promoters. Frederic Koch,Romain Fenouil,Marta Gut,Pierre Cauchy,Thomas K Albertet al. Nature Structural and Molecular Biology, 2011, 2 (4), epub ahead of print. ⟨10.1038/nsmb.2085⟩ Article dans une revue istex hal-00609674v1
H3K4 tri-methylation provides an epigenetic signature of active enhancers: Epigenetic signature of active enhancers Aleksandra Pekowska,Touati Benoukraf,Joaquin Zacarias-Cabeza,Mohamed Belhocine,Frederic Kochet al. EMBO Journal, 2011, 30 (20), pp.4198--4210. ⟨10.1038/emboj.2011.295⟩ Article dans une revue hal-01614961v1
Initiating RNA polymerase II and TIPs as hallmarks of enhancer activity and tissue-specificity F. Koch,J. C. Andrau Transcription, 2011, 2 (6), pp.263--8. ⟨10.4161/trns.2.6.18747⟩ Article dans une revue hal-02193318v1
CoCAS: a ChIP-on-chip analysis suite. Touati Benoukraf,Pierre Cauchy,Romain Fenouil,Adrien Jeanniard,Frederic Kochet al. Bioinformatics, 2009, 25 (7), pp.954-5. ⟨10.1093/bioinformatics/btp075⟩ Article dans une revue hal-00408403v1
The Ccr4-NOT deadenylase subunits CNOT7 and CNOT8 have overlapping roles and modulate cell proliferation A. Aslam,S. Mittal,F. Koch,J. C. Andrau,G. S. Winkler Molecular Biology of the Cell, 2009, 20 (17), pp.3840--50. ⟨10.1091/mbc.E09-02-0146⟩ Article dans une revue hal-02194079v1
Genome-wide RNA polymerase II: not genes only! Frederic Koch,Frederic Jourquin,Pierre Ferrier,Jean-Christophe Andrau Trends in Biochemical Sciences, 2008, 33 (6), pp.265-273. ⟨10.1016/j.tibs.2008.04.006⟩ Article dans une revue istex hal-00294059v1

Chapitre d'ouvrage (1)

Analyses of Promoter, Enhancer, and Nucleosome Organization in Mammalian Cells by MNase-Seq Cyril Esnault,Talha Magat,Encar García-Oliver,Jean Christophe Andrau Enhancers and Promoters, 2351, Springer US, pp.93-104, 2021, Methods in Molecular Biology, ⟨10.1007/978-1-0716-1597-3_5⟩ Chapitre d'ouvrage hal-03357156v1

Pré-publication, Document de travail (4)

Extracellular matrix stiffness modulates nuclear lamina organisation and sets nuclear conditions for PRC2 repression Alexia Pigeot,Martin Rey-Millet,Amal Zine El Aabidine,Antonio Trullo,Lea Costeset al. 2025 Pré-publication, Document de travail hal-05339295v1
G-quadruplexes are promoter elements controlling nucleosome exclusion and RNA polymerase II pausing Cyril Esnault,Encar Garcia-Oliver,Amal Zine El Aabidine,Marie-Cécile Robert,Talha Magatet al. 2023 Pré-publication, Document de travail hal-04286714v1
The control of transcriptional memory by stable mitotic bookmarking Mounia Lagha,Maëlle Bellec,Jérémy Dufourt,George Hunt,Hélène Lenden-Hasseet al. 2021 Pré-publication, Document de travail hal-03442288v1
Stochastic pausing at latent HIV-1 promoters generates transcriptional bursting Katiana Tantale,Encarnation Garcia-Oliver,Adèle L'Hostis,Yueyuxio Yang,Marie- Cécile Robertet al. 2020 Pré-publication, Document de travail hal-03019157v1