Jean-Christophe Gimel

Publications

Article dans une revue (45)

Design and characterization of propofol lipid nanocapsules: proof of concept for hospital preparation Emilie Tireau,Marie Bonnin,Guillaume Lefebvre,Louise Stinat,Etienne Chevremontet al. International Journal of Pharmaceutics, 2026, 692, pp.126640. ⟨10.1016/j.ijpharm.2026.126640⟩ Article dans une revue hal-05491490v1
Distribution of amiodarone between lipid nanocapsules and residual micelles: Tangential flow filtration as a purification method and its impact on cytotoxicity Jaspe Chen,Sophie Tamareille,Etienne Chèvremont,Jean-Christophe Gimel,Brice Calvignacet al. International Journal of Pharmaceutics, 2025, 677, pp.125651. ⟨10.1016/j.ijpharm.2025.125651⟩ Article dans une revue hal-05353785v1
Evidence of residual micellar structures in a lipid nanocapsule dispersion. A multi-technique approach Emilie Roger,Florence Franconi,Tran Anh Thu Do,Carl Simonsson,Benjamin Siegleret al. Journal of Controlled Release, 2023, 364, pp.700-717. ⟨10.1016/j.jconrel.2023.10.054⟩ Article dans une revue hal-04295223v1
Reactive precipitation of vaterite calcium carbonate microspheres in supercritical carbon dioxide-water dispersion by microfluidics Pierre Legout,Guillaume Lefebvre,Marie Bonnin,Jean Christophe Gimel,L. Benyahiaet al. Journal of Supercritical Fluids, 2022, 188, pp.105678. ⟨10.1016/j.supflu.2022.105678⟩ Article dans une revue hal-03737443v1
Galenic Lab-on-a-Chip concept for lipid nanocapsules production Nicolas Rolley,Marie Bonnin,Guillaume Lefebvre,Sylvain Verron,Sylwester Bargielet al. Nanoscale, 2021, 13, pp.11899 - 11912. ⟨10.1039/d1nr00879j⟩ Article dans une revue hal-03276290v1
NMR diffusometry: A new perspective for nanomedicine exploration Florence Franconi,Laurent Lemaire,Jean-Christophe Gimel,Samuel Bonnet,Patrick Saulnier Journal of Controlled Release, 2021, ⟨10.1016/j.jconrel.2021.07.025⟩ Article dans une revue hal-03291966v1
Synthesis of PDMS- b -POEGMA Diblock Copolymers and Their Application for the Thermoresponsive Stabilization of Water-Supercritical Carbon Dioxide Emulsions Pierre Legout,Guillaume Lefebvre,Marie Bonnin,Jean-Christophe Gimel,Lazhar Benyahiaet al. Langmuir, 2020, 36 (43), pp.12922−12932. ⟨10.1021/acs.langmuir.0c02194⟩ Article dans une revue hal-02973293v1
Modulation of protein release from penta-block copolymer microspheres Minh-Quan Le,Jean-Christophe Gimel,Xavier Garric,Thao-Quyen Nguyen-Pham,Cédric Paniaguaet al. European Journal of Pharmaceutics and Biopharmaceutics, 2020, 152, pp.175-182. ⟨10.1016/j.ejpb.2020.05.009⟩ Article dans une revue hal-02612734v1
Importance of Combining Advanced Particle Size Analysis Techniques To Characterize Cell-Penetrating Peptide–Ferrocifen Self-Assemblies Léna Guyon,Elise Lepeltier,Jean-Christophe Gimel,Brice Calvignac,Florence Franconiet al. Journal of Physical Chemistry Letters, 2019, 10 (21), pp.6613-6620. ⟨10.1021/acs.jpclett.9b01493⟩ Article dans une revue hal-02319158v1
NMR diffusometry data sampling optimization for mixture analysis Florence Franconi,Laurent Lemaire,Benjamin Siegler,Jean-Christophe Gimel,Patrick Saulnier Journal of Pharmaceutical and Biomedical Analysis, 2018, 148, pp.156-162. ⟨10.1016/j.jpba.2017.09.028⟩ Article dans une revue hal-02339344v1
A multi-scale approach for percolation transition and its application to cement setting Achutha Prabhu,Jean-Christophe Gimel,Andrés Ayuela,Silvia Arrese-Igor,Juan Gaiteroet al. Scientific Reports, 2018, 8 (1), ⟨10.1038/s41598-018-33918-6⟩ Article dans une revue hal-02339234v1
Spontaneous nano-emulsification: Process optimization and modeling for the prediction of the nanoemulsion’s size and polydispersity Guillaume Lefebvre,Jérémie Riou,Guillaume Bastiat,Emilie Roger,Kristen Frombachet al. International Journal of Pharmaceutics, 2017, 534 (1-2), pp.220-228. ⟨10.1016/j.ijpharm.2017.10.017⟩ Article dans une revue hal-02341597v1
Lipid nanocapsules maintain full integrity after crossing a human intestinal epithelium model Emilie Roger,Jean Christophe Gimel,Conor Bensley,Andrey S Klymchenko,Jean Pierre Benoit Journal of Controlled Release, 2017, 253, pp.11-18. ⟨10.1016/j.jconrel.2017.03.005⟩ Article dans une revue hal-03805634v1
How to design the surface of peptide-loaded nanoparticles for efficient oral bioavailability? Hélène Malhaire,Jean-Christophe Gimel,Emilie Roger,Jean-Pierre Benoît,Frédéric Lagarce Advanced Drug Delivery Reviews, 2016, pp.1-17. ⟨10.1016/j.addr.2016.03.011⟩ Article dans une revue hal-01392464v1
Brownian cluster dynamics with short range patchy interactions: Its application to polymers and step-growth polymerization A. Prabhu,Sujin Babu,J. Dolado,Jean Christophe Gimel The Journal of Chemical Physics, 2014, 141 (2), pp.024904. ⟨10.1063/1.4886585⟩ Article dans une revue hal-02351008v1
Nanoscale texture development of C-S-H gel: A computational model for nucleation and growth R. González-Teresa,J. Dolado,A. Ayuela,Jean-Christophe Gimel Applied Physics Letters, 2013, 103 (23), pp.234105. ⟨10.1063/1.4838396⟩ Article dans une revue hal-02565747v1
Fate of paclitaxel lipid nanocapsules in intestinal mucus in view of their oral delivery Anne-Claire Groo,Patrick Saulnier,Jean-Christophe Gimel,Julien Gravier,Caroline Ailhaset al. International Journal of Nanomedicine, 2013, pp.4291. ⟨10.2147/IJN.S51837⟩ Article dans une revue hal-02565768v1
Self-diffusion of non-interacting hard spheres in particle gels Jean-Christophe Gimel,Taco Nicolai Journal of Physics: Condensed Matter, 2011, 23 (23), pp.234115. ⟨10.1088/0953-8984/23/23/234115⟩ Article dans une revue hal-02351020v1
Crystallization and dynamical arrest of attractive hard spheres Sujin Babu,Jean-Christophe Gimel,Taco Nicolai The Journal of Chemical Physics, 2009, 130, pp.064504. ⟨10.1063/1.3074310⟩ Article dans une revue hal-00379777v1
Diffusion limited cluster aggregation with irreversible slippery bonds Sujin Babu,Jean-Christophe Gimel,Taco Nicolai European Physical Journal E: Soft matter and biological physics, 2008, 27, pp.297-308. ⟨10.1140/epje/i2008-10381-8⟩ Article dans une revue istex hal-00338461v1
The influence of bond rigidity and cluster diffusion on the self-diffusion of hard spheres with square-well interaction Sujin Babu,Jean-Christophe Gimel,Taco Nicolai,Cristiano de Michele The Journal of Chemical Physics, 2008, 128, pp.204504. ⟨10.1063/1.2925686⟩ Article dans une revue hal-00338457v1
Tracer diffusion in colloidal gels Sujin Babu,Jean-Christophe Gimel,Taco Nicolai Journal of Physical Chemistry B, 2008, 112 (3), pp.743-748. ⟨10.1021/jp076342+⟩ Article dans une revue hal-00206247v1
Self diffusion of reversibly aggregating spheres Sujin Babu,Jean-Christophe Gimel,Taco Nicolai The Journal of Chemical Physics, 2007, 127, pp.054503. ⟨10.1063/1.2756838⟩ Article dans une revue hal-00180979v1
Flocculation and percolation in reversible cluster-cluster aggregation. Sujin Babu,Manuel Rottereau,Taco Nicolai,Jean-Christophe Gimel,Dominique Durand European Physical Journal E: Soft matter and biological physics, 2006, 19, pp.203-211. ⟨10.1140/epje/e2006-00022-7⟩ Article dans une revue istex hal-00020136v1
Phase separation and percolation of reversibly aggregating spheres with a square-well attraction potential. Sujin Babu,Jean-Christophe Gimel,Taco Nicolai The Journal of Chemical Physics, 2006, 125, pp.184512-1-10. ⟨10.1063/1.2378832⟩ Article dans une revue hal-00134530v1
Depletion from a hard wall induced by aggregation and gelation. Manuel Rottereau,Taco Nicolai,Jean-Christophe Gimel European Physical Journal E: Soft matter and biological physics, 2005, 18, pp.37-40. ⟨10.1140/epje/i2005-10028-4⟩ Article dans une revue istex hal-00015710v1
Influence of the Brownian step size in off-lattice Monte-Carlo simulations of irreversible particle aggregation. Manuel Rottereau,Jean-Christophe Gimel,Taco Nicolai,Dominique Durand European Physical Journal E: Soft matter and biological physics, 2005, 18, pp.15-19. ⟨10.1140/epje/i2005-10027-5⟩ Article dans une revue istex hal-00015713v1
Monte Carlo simulation of particle aggregation and gelation: II. Pair correlation function and structure factor. Manuel Rottereau,Jean-Christophe Gimel,Taco Nicolai,Dominique Durand European Physical Journal E: Soft matter and biological physics, 2004, 15, pp.141-148. ⟨10.1140/epje/i2004-10045-9⟩ Article dans une revue istex hal-00020747v1
Monte Carlo simulation of particle aggregation and gelation: I. Growth, structure and size distribution of the clusters. Manuel Rottereau,Jean-Christophe Gimel,Taco Nicolai,Dominique Durand European Physical Journal E: Soft matter and biological physics, 2004, 15, pp.133-140. ⟨10.1140/epje/i2004-10044-x⟩ Article dans une revue istex hal-00020746v1
3d Monte Carlo simulations of site-bond continuum percolation of spheres. Manuel Rottereau,Jean-Christophe Gimel,Taco Nicolai,Dominique Durand European Physical Journal E: Soft matter and biological physics, 2003, 11, pp.61-64. ⟨10.1140/epje/i2003-10006-x⟩ Article dans une revue istex hal-00086915v1
Aggregation, gelation and phase separation of heat denatured globular proteins Dominique Durand,Jean-Christophe Gimel,Taco Nicolai Physica A: Statistical Mechanics and its Applications, 2002, 304 (1-2), pp.253-265. ⟨10.1016/S0378-4371(01)00514-3⟩ Article dans une revue istex hal-02565889v1
Relation between aggregation and phase separation: Three-dimensional Monte Carlo simulations Jean Christophe Gimel,Taco Nicolai,Dominique Durand Physical Review E , 2002, 66, pp.061405. ⟨10.1103/PhysRevE.66.061405⟩ Article dans une revue hal-02565879v1
Monte-Carlo simulation of transient gel formation and break-up during reversible aggregation Jean-Christophe Gimel,Taco Nicolai,Dominique Durand European Physical Journal E: Soft matter and biological physics, 2001, 5 (4), pp.415-422. ⟨10.1007/s101890170048⟩ Article dans une revue istex hal-02565950v1
Size distribution of percolating clusters on cubic lattices Jean-Christophe Gimel,Taco Nicolai,Dominique Durand Journal of Physics A: Mathematical and General (1975 - 2006), 2000, 33 (43), pp.7687-7697. ⟨10.1088/0305-4470/33/43/302⟩ Article dans une revue istex hal-02571441v1
A direct parallel implementation of the Hoshen–Kopelman algorithm for distributed memory architectures J.M. Teuler,Jean-Christophe Gimel Computer Physics Communications, 2000, 130 (1-2), pp.118-129. ⟨10.1016/S0010-4655(00)00046-1⟩ Article dans une revue istex hal-02565995v1
Crossing probabilities in one, two or three directions for percolation on a cubic lattice Jean-Christophe Gimel,Taco Nicolai,Dominique Durand Journal of Physics A: Mathematical and General (1975 - 2006), 1999, 32 (48), pp.L515-L519. ⟨10.1088/0305-4470/32/48/102⟩ Article dans une revue istex hal-02571430v1
Structure and size distribution of percolating clusters. Comparison with gelling systems Jean-Christophe Gimel,Taco Nicolai,Dominique Durand,Jean-Marie Teuler The European Physical Journal B: Condensed Matter and Complex Systems, 1999, 12 (1), pp.91-97. ⟨10.1007/s100510050982⟩ Article dans une revue istex hal-02567997v1
SDS Micelles at High Ionic Strength. A Light Scattering, Neutron Scattering, Fluorescence Quenching, and CryoTEM Investigation M. Almgren,Jean-Christophe Gimel,Ke Wang,G. Karlsson,K. Edwardset al. Journal of Colloid and Interface Science, 1998, 202 (2), pp.222-231. ⟨10.1006/jcis.1998.5503⟩ Article dans une revue istex hal-02567982v1
Fractality of Globular Protein Aggregates: From the Molecular to the Microscopic Level Pierre Aymard,Dominique Durand,Taco Nicolai,Jean-Christophe Gimel Fractals, 1997, 05 (supp02), pp.23-43. ⟨10.1142/S0218348X97000814⟩ Article dans une revue hal-02566961v1
Experimental evidence for a two-step process in the aggregation of β-lactoglobulin at pH 7 Pierre Aymard,Jean-Christophe Gimel,Taco Nicolai,Dominique Durand Journal de Chimie Physique et de Physico-Chimie Biologique, 1996, 93, pp.987-997. ⟨10.1051/jcp/1996930987⟩ Article dans une revue istex hal-02566883v1
Analysis of Relaxation Functions Characterized by a Broad Monomodal Relaxation Time Distribution Taco Nicolai,Jean Gimel,Robert Johnsen Journal de Physique II, 1996, 6 (5), pp.697-711. ⟨10.1051/jp2:1996206⟩ Article dans une revue istex jpa-00248328v1
A light scattering investigation of the sodium dodecyl sulfate–lysozyme system Jean-Christophe Gimel,Wyn Brown The Journal of Chemical Physics, 1996, 104 (20), pp.8112-8117. ⟨10.1063/1.471496⟩ Article dans une revue hal-02566933v1
Transition between flocculation and percolation of a diffusion-limited cluster-cluster aggregation process using three-dimensional Monte Carlo simulation Jean-Christophe Gimel,Dominique Durand,Taco Nicolai Physical Review B: Condensed Matter and Materials Physics (1998-2015), 1995, 51 (17), pp.11348-11357. ⟨10.1103/PhysRevB.51.11348⟩ Article dans une revue hal-02566531v1
Static structure factor of dilute solutions of polydisperse fractal aggregates Taco Nicolai,Dominique Durand,Jean-Christophe Gimel Physical Review B: Condensed Matter and Materials Physics (1998-2015), 1994, 50 (22), pp.16357-16363. ⟨10.1103/PhysRevB.50.16357⟩ Article dans une revue hal-02318707v1
Structure and distribution of aggregates formed after heat-induced denaturation of globular proteins Jean-Christophe Gimel,Dominique Durand,Taco Nicolai Macromolecules, 1994, 27 (2), pp.583-589. ⟨10.1021/ma00080a037⟩ Article dans une revue istex hal-02318708v1

Poster de conférence (8)

Design et évaluation pré-clinique d'un dispositif microfluidique d’infusion pour la thérapie des tumeurs cérébrales Laurent Lemaire,Mathieu Weitten,Gregory Hilairet,Isabelle Verdu,Florence Franconiet al. 17èmes journées du Cancéropôle Grand-Ouest. Vannes, Jun 2023, Vannes, France Poster de conférence hal-04105790v1
Experimental evidence of residual micellar structures in lipid nanocapsules suspensions Tran Anh Thu Do,Emilie Roger,Florence Franconi,Benjamin Siegler,Rodolphe Perrotet al. SFnano, Dec 2022, Strasbourg, France. Poster de conférence hal-03890468v1
Is dynamic light scattering a good method to characterize self-assemblies of cell penetrating peptide-ferrocifen conjugates? Léna Guyon,Elise Lepeltier,Jean-Christophe Gimel,Brice Calvignac,Florence Franconiet al. SF Nano, Dec 2019, Dijon, France Poster de conférence hal-02617249v1
Synthesis and characterization of cell-penetrating peptide-ferrocifen self-assemblies Léna Guyon,Elise Lepeltier,Jean-Christophe Gimel,Brice Calvignac,Florence Franconiet al. IUPAC, Jul 2019, Paris, France Poster de conférence hal-02617358v1
Fluid-poroelastic interface modelling for an implantable medical device: Application to brain tumours treatment Julien Rolland,Alexei Lozinski,Jean-Christophe Gimel,Florence Franconi,Laurent Lemaireet al. 14ème journées d'étude des milieux poreux, 2018, Nantes, France. , 2018 Poster de conférence hal-02616013v1
Effect of process parameters on morphology and release profile of Penta-block PLGA-based Microspheres Minh Quan Le,Jean Christophe Gimel,Xavier Garric,Marie-Claire Venier-Julienne 2nd European conference on pharmaceutics (APGI), 2017, Krakow, Poland Poster de conférence hal-02631540v1
Aggregation of wheat prolamins: a computer simulation study Achutha Prabhu,Denis Renard,Jean-Christophe Gimel Journées Ecole Doctorale Matières, Molécules, Matériaux en Pays de la Loire 3MPL, Jun 2011, Le Mans, France. 2011 Poster de conférence hal-02802747v1
Aggregation of wheat prolamins: a computer simulation study Achutha Prabhu,Denis Renard,Jean-Christophe Gimel Journées Ecole Doctorale Matières, Molécules, Matériaux en Pays de la Loire 3MPL, Jun 2010, Nantes, France. 2010 Poster de conférence hal-02814739v1

Communication dans un congrès (10)

Development of the Galenic Lab-on-a-chip and ​Therapy-on-a-chip concepts for drug formulation / delivery Laurent Lemaire,Guillaume Brotons,Marie Bonnin,Guillaume Lefebvre,Florence Franconiet al. Journées plenières du GDR MicroNanofluidique, Apr 2023, Lyon, France Communication dans un congrès hal-04105812v1
Précipitation réactive en milieu CO2 supercritique de microsphères nanostructurées de carbonate de calcium par procédé microfluidique Pierre Legout,Guillaume Lefebvre,Marie Bonnin,Jean-Christophe Gimel,Lazhar Benyahiaet al. 18ème Congrès de la Société Française de Génie des Procédés, SFGP, Nov 2022, Toulouse, France Communication dans un congrès hal-04124139v1
Formulation of vancomycin nanocomplexes through a microfluidic process for the treatment of Clostridium Difficile infections Sébastien Wang,Brice Calvignac,Guillaume Lefebvre,Camille Savary,Jean Christophe Gimelet al. SFNano Annual Meeting 2021, SFNano, Dec 2021, Angers, France Communication dans un congrès hal-03480264v1
Caractérisation de l'activité interfaciale et du comportement auto-associatif de copolymères à blocs amphiphiles : application à la formulation d'émulsions Eau/CO2 supercritique pour la précipitation réactive de CaCO3 Pierre Legout,Olivier Colombani,Guillaume Lefevbre,Marie Bonnin,Jean Christophe Gimelet al. Congrès de la Société Française de Génie des Procédés, Oct 2019, Nantes, France Communication dans un congrès hal-03472842v1
Fluid-poroelastic interface modelling for an implantable medical device: Application to brain tumours treatment Julien Rolland,Alexei Lozinski,Brice Calvignac,Jean-Christophe Gimel,Florence Franconiet al. 3rd Mathematical Biology Modelling days of Besançon, 2018, Besançon, France Communication dans un congrès hal-02616012v1
Nanoassemblies formed by polyarginine-ferrocifen conjugates for lung cancer treatment Léna Guyon,Elise Lepeltier,Brice Calvignac,Nolwenn Lautram,Bénédicte Lelièvreet al. SF Nano, Dec 2018, Montpellier, France Communication dans un congrès hal-02617897v1
Effect of Nano Seeds in C-S-H Gel Formation: Simulation Study from the Colloidal Point of View Achutha Prabhu,Jean-Christophe Gimel,A. Ayuela,Jorge S. Dolado CONCREEP 10, 2015, Vienne, Austria. ⟨10.1061/9780784479346.104⟩ Communication dans un congrès hal-01393852v1
Assessment of the diffusion coefficient of nanocarriers with the fluorescence recovery technique in gastrointestinal mucus Alison Dénarnaud,Jérémie Riou,Rodolphe Perrot,Emilie Roger,Frédéric Lagarceet al. Crossing Biological Barriers - Advances in Nanocarriers Design for Targeted Drug Delivery, 2015, Dresde, Germany Communication dans un congrès hal-02615956v1
Particle diffusion in colloid gels Dominique Durand,Gireeshkumar Balakrishnan Nair,Sujin-B. Babu,Taco Nicolaï,Jean-Christophe Gimel 3rd International Conference on Polymer Processing and Characterization, 2014, Kottayam, Inde Communication dans un congrès hal-03180814v1
Quantitative analysis of protein gel structure by confocal laser scanning microscopy Komla Ako,Lydiane Bécu,Taco Nicolai,Jean-Christophe Gimel,Dominique Durand 14th European Microscopy Congress (ECM 2008), Sep 2008, Aachen, Germany. pp.757-758, ⟨10.1007/978-3-540-85226-1_379⟩ Communication dans un congrès istex hal-00338459v1

Brevet (4)

Formulation de nanocapsules lipidiques par procédé continu d’inversion de phase en concentration Brice Calvignac,Florian Fouchet,Jean-Christophe Gimel,Emilie Roger,Nicolas Rolleyet al. France, N° de brevet: WO2021/014109. 2020 Brevet hal-03133816v1
Formulation de nanocapsules lipidiques par procédé continu d’inversion de phase en concentration Brice Calvignac,Florian Fouchet,Jean-Christophe Gimel,Emilie Roger,Nicolas Rolleyet al. France, N° de brevet: FR30990669. 2019 Brevet hal-03133819v1
Dispositif medical implantable d’injection locoregionale Brice Calvignac,Jean-Christophe Gimel,Florence Franconi,Laurent Lemaire France, N° de brevet: WO2018/015690. 2017 Brevet hal-03133820v1
Dispositif medical implantable d’injection locoregionale Brice Calvignac,Jean-Christophe Gimel,Florence Franconi,Laurent Lemaire France, N° de brevet: FR3054137A1. 2016 Brevet hal-02308068v1

Autre publication scientifique (4)

Diffusion of nanotracers in complex media Jean-Christophe Gimel 2016 Autre publication scientifique hal-02615959v1
Transports de nanoparticules dans des matrices complexes Jean-Christophe Gimel 2016 Autre publication scientifique hal-02615960v1
Step polymerization in various solvent conditions. A computer simulation approach using &quot;Patchy Brownian Cluster Dynamics&quot;. Achutha Prabhu,Jorge S. Dolado,Jean-Christophe Gimel 2015 Autre publication scientifique hal-02615974v1
Transport de nanovecteurs dans des matrices complexes Jean-Christophe Gimel 2015 Autre publication scientifique hal-02615951v1