Jean-Hugues Renault

113
Documents

Présentation

Head of the Institut of Molecular Chemistry of Reims, UMR CNRS 7312

Publications

Publications

Metabolome and ( R )-Mellein Production in Neofusicoccum parvum Strains are Differentially Affected by Grapevine Woody Biomass

Julián Restrepo-Leal , Florence Fontaine , Simon Remy , Jochen Fischer-Schuch , Nicolas Borie et al.

Journal of Agricultural and Food Chemistry, 2025, 73 (22), pp.13381-13392. ⟨10.1021/acs.jafc.5c03139⟩

Article dans une revue hal-05126196v1

Unlocking the Potential of Water-Insoluble Natural Polymers: Isolation, Characterization, and 2D NMR Quantification of cis -1,4-Poly-β-myrcene in Chios Mastic Gum

Stavros Beteinakis , Eleni Mikropoulou , Dimitris Michailidis , Apostolis Angelis , Martina Haack et al.

Journal of Natural Products, 2025, ⟨10.1021/acs.jnatprod.5c00256⟩

Article dans une revue hal-05045866v1
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Distinct oxidative and photosynthetic responses to betulin and betulone in the freshwater microalgae Chlamydomonas reinhardtii

Anthony Montembault , Damien Rioult , Iris Barjhoux , Sandra Villaume , Nathalie Gaveau et al.

Ecotoxicology and Environmental Safety, 2025, 303, pp.119033. ⟨10.1016/j.ecoenv.2025.119033⟩

Article dans une revue hal-05329630v1

Integrated online DPPH-assisted multimodal dereplication workflow for identifying antioxidant compounds in complex mixtures and its application to a supercritical CO2 extract of Makwaen pepper by-product

Jérémy Perret , Shahad Ragheed-Georges , Simon Remy , Julien Cordonnier , Charlotte Sayagh et al.

Journal of Chromatography A, 2025, 1757, pp.466172. ⟨10.1016/j.chroma.2025.466172⟩

Article dans une revue hal-05329664v1
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A selective genetic algorithm - PLS-DA approach based on untargeted LC-HRMS: Application to complex biomass samples

Ian Ramtanon , Marion Lacoue-Nègre , Alexandra Berlioz-Barbier , Agnès Le Masle , Jean-Hugues Renault

Chemometrics and Intelligent Laboratory Systems, 2025, 261, pp.105381. ⟨10.1016/j.chemolab.2025.105381⟩

Article dans une revue hal-04996495v2
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Sustainable and Scalable Enzymatic Production, Structural Elucidation, And Biological Evaluation of Novel Phlorizin Analogues

Laurène Minsat , Yueying Li , Cédric Peyrot , Agathe Martinez , Nicolas Borie et al.

ChemSusChem, 2025, 18 (8), pp.e202401498. ⟨10.1002/cssc.202401498⟩

Article dans une revue hal-04869885v1
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Chemical imaging of lignocellulosic biomass: Mapping plant chemistry

Noah Remy , David Touboul , Edith Nicol , Séverine Humbert , Luminita Duma et al.

Biotechnology Advances, 2025, 85, pp.108696. ⟨10.1016/j.biotechadv.2025.108696⟩

Article dans une revue hal-05240023v1
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Resistance of Pseudomonas aeruginosa and Staphylococcus aureus to the airway epithelium oxidative response assessed by a cell-free in vitro assay

Maïwenn Petithomme-Nanrocki , Nathan Nicolau-Guillaumet , Nicolas Borie , Arnaud Haudrechy , Jean-Hugues Renault et al.

PLoS ONE, 2024, 19 (8), pp.e0306259. ⟨10.1371/journal.pone.0306259⟩

Article dans une revue hal-04679703v1
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Phytochemical characterization and biological activities of Stenomesson miniatum bulb extract, a medicinal plant of the Andes

Mariacaterina Lianza , Carmela Fimognari , Jean-Marc Nuzillard , Ferruccio Poli , Jean-Hugues Renault et al.

Plant Biosystems, 2024, 158 (1), pp.182-189. ⟨10.1080/11263504.2023.2293037⟩

Article dans une revue hal-04338332v1
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A new generation of ecocatalysts ® —from Invasive Alien Species to sustainable and biosourced glyceryl fatty esters

Arthur Lasbleiz , Franck Pelissier , Jean-Hugues Renault , Claire M Grison , Yves-Marie Legrand et al.

Comptes Rendus. Chimie, 2024, 27 (S2), pp.1-13. ⟨10.5802/crchim.273⟩

Article dans une revue hal-04526959v1

Production of high molecular-ordered stilbene oligomers for the study of their biological activity: total synthesis, bio-catalyzed synthesis and production by plant systems

Philippe Jeandet , Md. Sahab Uddin , Christophe Clément , Aziz Aziz , Cédric Jacquard et al.

Natural Product Reports, 2023, 40 (5), pp.1045-1057. ⟨10.1039/D2NP00073C⟩

Article dans une revue hal-04616248v1
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La valorisation des écorces d’essences champardennaises pour la cosmétique et la pharmacie.

Pierre Darme , Jérémy Spalenka , Julien Cordonnier , Simon Remy , Sandie Escotte-Binet et al.

L'Actualité Chimique, 2023, 484-485, pp.53-61

Article dans une revue hal-04184375v1
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A Combined Liquid Chromatography Trapped Ion Mobility Tandem High Resolution Mass Spectrometry and Multivariate Analysis Approach for the Determination of Enzymatic Reactivity Descriptors in Biomass Hydrolysates

Ian Ramtanon , Alexandra Berlioz-Barbier , Simon Remy , Jean-Hugues Renault , Agnès Le Masle

Journal of Chromatography A, 2023, 1706, pp.464277. ⟨10.1016/j.chroma.2023.464277⟩

Article dans une revue hal-04290959v1
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Combining Laccase-Mediated Dimerization of Resveratrol and Centrifugal Partition Chromatography: Optimization of E -Labruscol Production and Identification of New Resveratrol Dimers

Emmanuel Sursin , Amandine Flourat , Z. Akissi , Agathe Martinez , Nicolas Borie et al.

ACS Sustainable Chemistry & Engineering, 2023, 11 (31), pp.11559-11569. ⟨10.1021/acssuschemeng.3c01997⟩

Article dans une revue hal-04169252v1

Anti-tumoral Effect of Thymelaea hirsuta L. Extracts in Colorectal Cancer Cells

Iheb Toumi , Sonia Yatouji , Nicolas Borie , Simon Remy , Jean-Hugues Renault et al.

Anti-Cancer Agents in Medicinal Chemistry, 2023, 23 (6), pp.687-698. ⟨10.2174/1871520622666220826095035⟩

Article dans une revue istex hal-04616265v1
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Versa DB: Assisting 13 C NMR and MS/MS Joint Data Annotation Through On-Demand Databases

Julien Cordonnier , Simon Remy , Jean-Hugues Renault , Jean-Marc Nuzillard

Chemistry–Methods, 2023, pp.e202300020. ⟨10.1002/cmtd.202300020⟩

Article dans une revue hal-04163851v1
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Anti-Toxoplasma gondii effect of lupane-type triterpenes from the bark of black alder (Alnus glutinosa) and identification of a potential target by reverse docking

Pierre Darme , Sandie Escotte-Binet , Julien Cordonnier , Simon Remy , Jane Hubert et al.

Parasite, 2022, 29, pp.7. ⟨10.1051/parasite/2022008⟩

Article dans une revue hal-03565091v1
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The Three Pillars of Natural Product Dereplication. Alkaloids from the Bulbs of Urceolina peruviana (C. Presl) J.F. Macbr. as a Preliminary Test Case

Mariacaterina Lianza , Ritchy Leroy , Carine Machado Rodrigues , Nicolas Borie , Charlotte Sayagh et al.

Molecules, 2021, 26 (3), pp.637. ⟨10.3390/molecules26030637⟩

Article dans une revue hal-03126780v1
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Synthesis of Biobased Phloretin Analogues: An Access to Antioxidant and Anti-Tyrosinase Compounds for Cosmetic Applications

Laurène Minsat , Cédric Peyrot , Fanny Brunissen , Jean-Hugues Renault , Florent Allais

Antioxidants , 2021, 10 (4), pp.512. ⟨10.3390/antiox10040512⟩

Article dans une revue hal-03408325v1
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Investigation of antiparasitic activity of ten European tree bark extracts on Toxoplasma gondii and bioguided identification of triterpenes in Alnus glutinosa barks

Pierre Darme , Jérémy Spalenka , Jane Hubert , Sandie Escotte-Binet , Laurent Debelle et al.

Antimicrobial Agents and Chemotherapy, 2021, 66 (1), pp.e01098-21. ⟨10.1128/AAC.01098-21⟩

Article dans une revue hal-03374475v1
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AMIDE v2: High-Throughput Screening Based on AutoDock-GPU and Improved Workflow Leading to Better Performance and Reliability

Pierre Darme , Manuel Dauchez , Arnaud Renard , Laurence Voutquenne-Nazabadioko , Dominique Aubert et al.

International Journal of Molecular Sciences, 2021, 22, ⟨10.3390/ijms22147489⟩

Article dans une revue hal-03287272v1
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Accessing p‐Hydroxycinnamic acids: chemical synthesis, biomass recovery or engineered microbial production?

Amandine Flourat , Jeanne Combes , Claire Bailly-Maitre-Grand , Kevin Magnien , Arnaud Haudrechy et al.

ChemSusChem, 2021, 14 (1), pp.118-129. ⟨10.1002/cssc.202002141⟩

Article dans une revue hal-02980663v1
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Dereplication of Natural Extracts Diluted in Propylene Glycol, 1,3-Propanediol and Glycerin. Comparison of Leontopodium alpinum Cass. (Edelweiss) Extracts as a Case Study

Marine Canton , Stéphane Poigny , Richard Roe , Jean-Marc Nuzillard , Jean-Hugues Renault

Cosmetics, 2021, 8 (1), pp.10. ⟨10.3390/cosmetics8010010⟩

Article dans une revue hal-03126785v1

Comprehensive lipid profiling of Microchloropsis gaditana by liquid chromatography - (tandem) mass spectrometry: Bead milling and extraction solvent effects

Gaela Cauchie , Guillaume Delfau-Bonnet , Guillaume Caulier , Anne-Lise Hantson , Jean-Hugues Renault et al.

Algal Research - Biomass, Biofuels and Bioproducts, 2021, 58, pp.102388. ⟨10.1016/j.algal.2021.102388⟩

Article dans une revue hal-03284365v1
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Bacterial rhamnolipids and their 3-hydroxyalkanoate precursors activate Arabidopsis innate immunity through two independent mechanisms

Romain Schellenberger , Jérôme Crouzet , Arvin Nickzad , Lin-Jie Shu , Alexander Kutschera et al.

Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (39), pp.e2101366118. ⟨10.1073/pnas.2101366118⟩

Article dans une revue hal-03356415v1
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Implementation of an Enzyme Membrane Reactor to Intensify the α-O-Glycosylation of Resveratrol Using Cyclodextrins

Irina Ioannou , Eduardo Barboza , Gaëlle Willig , Thomas Marié , Andreïa Texeira et al.

Pharmaceuticals, 2021, 14 (4), pp.319. ⟨10.3390/ph14040319⟩

Article dans une revue hal-03190124v1

Chemical Profile and Antimicrobial Activity of the Fungus-Growing Termite Strain Macrotermes Bellicosus Used in Traditional Medicine in the Republic of Benin

Dima Hammoud Mahdi , Jane Hubert , Jean-Hugues Renault , Agathe Martinez , Andreas Schubert et al.

Molecules, 2020, 25 (21), pp.5015. ⟨10.3390/molecules25215015⟩

Article dans une revue hal-02984802v1
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Pilot continuous centrifugal liquid-liquid extraction of extra virgin olive oil biophenols and gram-scale recovery of pure oleocanthal, oleacein, MFOA, MFLA and hydroxytyrosol

Apostolis Angelis , Dimitris Michailidis , Lemonia Antoniadi , Panagiotis Stathopoulos , Vasiliki Tsantila et al.

Separation and Purification Technology, 2020, 255, pp.117692. ⟨10.1016/j.seppur.2020.117692⟩

Article dans une revue hal-02934323v1
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Dereplication of Natural Extracts Diluted in Glycerin: Physical Suppression of Glycerin by Centrifugal Partition Chromatography Combined with Presaturation of Solvent Signals in 13C-Nuclear Magnetic Resonance Spectroscopy

Marine Canton , Jane Hubert , Stéphane Poigny , Richard Roe , Yves Brunel et al.

Molecules, 2020, 25 (21), pp.5061. ⟨10.3390/molecules25215061⟩

Article dans une revue hal-03191067v1
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Multiple solvent signal presaturation and decoupling artifact removal in 13C{1H} nuclear magnetic resonance

Marine Canton , Richard Roe , Stéphane Poigny , Jean-Hugues Renault , Jean-Marc Nuzillard

Magnetic Resonance, 2020, 1 (2), pp.155-164. ⟨10.5194/mr-1-155-2020⟩

Article dans une revue hal-02900066v1
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(S)-γ-hydroxymethyl-α,β-butenolide (aka HBO), a Valuable Chiral Synthon: Syntheses, Reactivity and Applications

Amandine Flourat , Arnaud Haudrechy , Florent Allais , Jean-Hugues Renault

Organic Process Research and Development, 2020, 24 (5), pp.615-636. ⟨10.1021/acs.oprd.9b00468⟩

Article dans une revue hal-02400639v1
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In Vitro and In Vivo Activity of Anogeissus leiocarpa Bark Extract and Isolated Metabolites against Toxoplasma gondii

Jérémy Spalenka , Jane Hubert , Laurence Voutquenne-Nazabadioko , Sandie Escotte-Binet , Nicolas Borie et al.

Planta Medica, 2020, 86 (4), pp.294-302. ⟨10.1055/a-1088-8449⟩

Article dans une revue hal-02498431v1
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Abundant Extractable Metabolites from Temperate Tree Barks: The Specific Antimicrobial Activity of Prunus Avium Extracts

Amin Abedini , Marius Colin , Jane Hubert , Émilie Charpentier , Apostolis Angelis et al.

Antibiotics, 2020, 9 (3), pp.111. ⟨10.3390/antibiotics9030111⟩

Article dans une revue hal-02507587v1
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Accelerating Metabolite Identification in Natural Product Research: Toward an Ideal Combination of Liquid Chromatography–High-Resolution Tandem Mass Spectrometry and NMR Profiling, in Silico Databases, and Chemometrics

Jean-Luc Wolfender , Jean-Marc Nuzillard , Justin van Der Hooft , Jean-Hugues Renault , Samuel Bertrand

Analytical Chemistry, 2019, 91 (1), pp.704-742. ⟨10.1021/acs.analchem.8b05112⟩

Article dans une revue hal-01992885v1

The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research

James Mcalpine , Shao-Nong Chen , Andrei Kutateladze , John Macmillan , Giovanni Appendino et al.

Natural Product Reports, 2019, 36 (1), pp.35-107. ⟨10.1039/C7NP00064B⟩

Article dans une revue hal-05521958v1
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The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research

James B. Mcalpine , Shao-Nong Chen , Andrei Kutateladze , John Macmillan , Giovanni Appendino et al.

Natural Product Reports, 2019, 36 (1), pp.35-107. ⟨10.1039/c7np00064b⟩

Article dans une revue hal-01995061v1
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First Total Synthesis of (β-5)-(β-O-4) Dihydroxytrimer and Dihydrotrimer of Coniferyl Alcohol (G): Advanced Lignin Model Compounds

Amandine Flourat , Aurélien a M Peru , Arnaud Haudrechy , Jean-Hugues Renault , Florent Allais

Frontiers in Chemistry, 2019, 7, pp.842. ⟨10.3389/fchem.2019.00842⟩

Article dans une revue hal-02400612v1
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Two new bis-iridoids isolated from Scabiosa stellata and their antibacterial, antioxidant, anti-tyrosinase and cytotoxic activities

Meryem Lehbili , Abdulmagid Alabdul Magid , Jane Hubert , Ahmed Kabouche , Laurence Voutquenne-Nazabadioko et al.

Fitoterapia, 2018, 125, pp.41 - 48. ⟨10.1016/j.fitote.2017.12.018⟩

Article dans une revue hal-03351296v1

Enzymatic Synthesis of Resveratrol α-Glycosides from β-Cyclodextrin-Resveratrol Complex in Water

Thomas Marie , Gaëlle Willig , Andreia Teixeira , Eduardo Gazaneo Barboza , Alexis Kotland et al.

ACS Sustainable Chemistry & Engineering, 2018, 6 (4), pp.5370-5380. ⟨10.1021/acssuschemeng.8b00176⟩

Article dans une revue hal-01963641v1

Discovery of New Inhibitors of Toxoplasma gondii via the Pathogen Box

Jérémy Spalenka , Sandie Escotte-Binet , Ali Bakiri , Jane Hubert , Jean-Hugues Renault et al.

Antimicrobial Agents and Chemotherapy, 2018, 62 (2), pp.78-83. ⟨10.1128/AAC.01640-17⟩

Article dans une revue hal-01995050v1
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GABA and GABA-Alanine from the Red Microalgae Rhodosorus marinus Exhibit a Significant Neuro-Soothing Activity through Inhibition of Neuro-Inflammation Mediators and Positive Regulation of TRPV1-Related Skin Sensitization

Amandine Scandolera , Jane Hubert , Anne Humeau , Carole Lambert , Audrey de Bizemont et al.

Marine drugs, 2018, 16 (3), pp.96. ⟨10.3390/md16030096⟩

Article dans une revue hal-01904945v1

Chimie du végétal et produits innovants à forte valeur ajoutée

Abdulmagid Alabdul-Magid , Christophe Bliard , Stéphanie Boudesocque , Sandrine Bouquillon , Xavier Coqueret et al.

L'Actualité Chimique, 2018, 427-428, pp.25-33

Article dans une revue hal-02266305v1
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Reconstruction of HMBC Correlation Networks: A Novel NMR-based Contribution to Metabolite Mixture Analysis

Ali Bakiri , Jane Hubert , Romain Reynaud , Carole Lambert , Agathe Martinez et al.

Journal of Chemical Information and Modeling, 2018, 58 (2), pp.262-270. ⟨10.1021/acs.jcim.7b00653⟩

Article dans une revue hal-01692926v1
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Advanced NMR-Based Structural Investigation of Glucosinolates and Desulfoglucosinolates

Nada Ibrahim , Ingrid Allart-Simon , Gina de Nicola , Renato Iori , Jean-Hugues Renault et al.

Journal of Natural Products, 2018, 81 (2), pp.323 - 334. ⟨10.1021/acs.jnatprod.7b00776⟩

Article dans une revue hal-01904948v1
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Computer-aided Dereplication and Structure Elucidation of Natural Products at the University of Reims

Ali Bakiri , Bertrand Plainchont , Vicente de Paulo Emerenciano , Romain Reynaud , Jane Hubert et al.

Molecular Informatics, 2017, 36 (10), pp.1700027. ⟨10.1002/minf.201700027⟩

Article dans une revue hal-01904951v1

Schinus terebinthifolius countercurrent chromatography (Part III): Method transfer from small countercurrent chromatography column to preparative centrifugal partition chromatography ones as a part of method development

Fernanda das Neves Costa , Jane Hubert , Nicolas Borie , Alexis Kotland , Peter Hewitson et al.

Journal of Chromatography A, 2017, 1487 (11), pp.77-82. ⟨10.1016/j.chroma.2016.11.051⟩

Article dans une revue istex hal-01995035v1
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Purification of dirucotide, a synthetic 17-aminoacid peptide, by ion exchange centrifugal partition chromatography

Leslie Boudesocque-Delaye , Luciano Forni , Agathe Martinez , Jean-Marc Nuzillard , Matthieu Giraud et al.

Journal of Chromatography A, 2017, 1513, pp.78-83. ⟨10.1016/j.chroma.2017.07.003⟩

Article dans une revue hal-01608841v1
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Cytotoxicity of Labruscol, a New Resveratrol Dimer Produced by Grapevine Cell Suspensions, on Human Skin Melanoma Cancer Cell Line HT-144

Laetitia Nivelle , Jane Hubert , Eric Courot , Nicolas Borie , Jean-Hugues Renault et al.

Molecules, 2017, 22 (11), pp.1940. ⟨10.3390/molecules22111940⟩

Article dans une revue hal-02181902v1
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Anti-Cancer Activity of Resveratrol and Derivatives Produced by Grapevine Cell Suspensions in a 14 L Stirred Bioreactor.

Laetitia Nivelle , Jane Hubert , Eric Courot , Philippe Jeandet , Aziz Aziz et al.

Molecules, 2017, 22 (3), pp.474. ⟨10.3390/molecules22030474⟩

Article dans une revue hal-01555716v1
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Computer-Aided 13 C NMR Chemical Profiling of Crude Natural Extracts without Fractionation

Ali Bakiri , Jane Hubert , Romain Reynaud , Sylvie Lanthony , Dominique Harakat et al.

Journal of Natural Products, 2017, 80 (5), pp.1387 - 1396. ⟨10.1021/acs.jnatprod.6b01063⟩

Article dans une revue hal-01904954v1

An integrated process for the recovery of high added-value compounds from olive oil using solid support free liquid-liquid extraction and chromatography techniques

Apostolis Angelis , Mahmoud Hamzaoui , Nektarios Aligiannis , Theodora Nikou , Dimitris Michailidis et al.

Journal of Chromatography A, 2017, 1491, pp.126-136. ⟨10.1016/j.chroma.2017.02.046⟩

Article dans une revue hal-01995040v1
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Dereplication strategies in natural product research: How many tools and methodologies behind the same concept?

Jane Hubert , Jean-Marc Nuzillard , Jean-Hugues Renault

Phytochemistry Reviews, 2017, 16 (1), pp.55 - 95. ⟨10.1007/s11101-015-9448-7⟩

Article dans une revue hal-01904964v1

13 C NMR and LC-MS Profiling of Stilbenes from Elicited Grapevine Hairy Root Cultures

Leo-Paul Tisserant , Jane Hubert , Michelle Lequart-Pillon , Nicolas Borie , Nicolas Maurin et al.

Journal of Natural Products, 2016, 79 (11), pp.2846 - 2855. ⟨10.1021/acs.jnatprod.6b00608⟩

Article dans une revue hal-01904968v1

Purification of alkaloids from Catharanthus roseus by pH-zone refining centrifugal partition chromatography: process intensification and scale up

Sébastien Chollet , A Kotland , Jm Autret , G Calmels , C Diard et al.

Planta Medica, 2016, 81 (S 01), pp.S1-S381. ⟨10.1055/s-0036-1596139⟩

Article dans une revue hal-04660234v1

Removal of pesticides from wastewater by ion pair Centrifugal Partition Extraction using betaine-derived ionic liquids as extractants

Yannick de Gaetano , Jane Hubert , Aminou Mohamadou , Stéphanie Boudesocque , Richard Plantier-Royon et al.

Chemical Engineering Journal, 2016, 285, pp.596 - 604. ⟨10.1016/j.cej.2015.10.012⟩

Article dans une revue hal-01889373v1

Industrial case study on alkaloids purification by pH-zone refining centrifugal partition chromatography

Alexis Kotland , Sébastien Chollet , Catherine Diard , Jean-Marie Autret , Jérémy Meucci et al.

Journal of Chromatography A, 2016, 1474, pp.59 - 70. ⟨10.1016/j.chroma.2016.10.039⟩

Article dans une revue istex hal-01935722v1

Bio-Guided Isolation of Methanol-Soluble Metabolites of Common Spruce (Picea abies) Bark by-Products and Investigation of Their Dermo-Cosmetic Properties

Apostolis Angelis , Jane Hubert , Nektarios Aligiannis , Rozalia Michalea , Amin Abedini et al.

Molecules, 2016, 21 (11), pp.1586. ⟨10.3390/molecules21111586⟩

Article dans une revue hal-01904974v1

Bioactivity-guided identification of antimicrobial metabolites in Alnus glutinosa bark and optimization of oregonin purification by Centrifugal Partition Chromatography

Amin Abedini , Sébastien Chollet , Apostolis Angelis , Nicolas Borie , Jean-Marc Nuzillard et al.

Journal of Chromatography B - Analytical Technologies in the Biomedical and Life Sciences, 2016, 1029-1030, pp.121 - 127. ⟨10.1016/j.jchromb.2016.07.021⟩

Article dans une revue istex hal-01904982v1

In Vitro Dermo-Cosmetic Evaluation of Bark Extracts from Common Temperate Trees

Jane Hubert , Apostolis Angelis , Ali Aligiannis , Michalea Rosalia , Amin Abedini et al.

Planta Medica, 2016, 82 (15), pp.1351 - 1358. ⟨10.1055/s-0042-110180⟩

Article dans une revue hal-01904993v1

Intensified separation of steviol glycosides from a crude aqueous extract of <em>Stevia rebaudiana</em> leaves using centrifugal Partition chromatography

Jane Hubert , Nicolas Borie , Sébastien Chollet , Joël Perret , Claire Barbet Massin et al.

Planta Medica, 2015, 81 (17), pp.1614-1620. ⟨10.1055/s-0035-1545840⟩

Article dans une revue hal-02630678v1

Modern Separation Techniques for the Isolation of Natural Products

Jean-Hugues Renault

Planta Medica, 2015, 81 (17), pp.1569-1569

Article dans une revue hal-01995002v1
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Isolation of Flavonoids and Triterpenoids from the Fruits of Alphitonia Neocaledonica and Evaluation of their Anti-oxidant, Anti-tyrosinase and Cytotoxic Activities

Dima Muhammad , Jane Hubert , Nathalie Lalun , Jean-Hugues Renault , Hélène Bobichon et al.

Phytochemical Analysis, 2015, 26 (2), pp.137-144. ⟨10.1002/pca.2545⟩

Article dans une revue istex hal-01994982v1

Modeling pH-zone refining countercurrent chromatography: A dynamic approach

Alexis Kotland , Sébastien Chollet , Jean-Marie Autret , Catherine Diard , Luc Marchal et al.

Journal of Chromatography A, 2015, 1391, pp.80-87. ⟨10.1016/j.chroma.2015.03.005⟩

Article dans une revue istex hal-01994995v1

Separation of neutral and acidic triterpenes from Mastic gum using Centrifugal Partition Chromatography (CPC) and Supercritical Fluid Chromatography (SFC-CO2)

M. Hamzaoui , A Angelis , V Laskari , A Termentzi , J Hubert et al.

Planta Medica, 2015, 81 (16)

Article dans une revue hal-01995004v1

Exploiting the Complementarity between Dereplication and Computer-Assisted Structure Elucidation for the Chemical Profiling of Natural Cosmetic Ingredients: Tephrosia purpurea as a Case Study

Jane Hubert , Sébastien Chollet , Sylvain Purson , Romain Reynaud , Dominique Harakat et al.

Journal of Natural Products, 2015, 78 (7), pp.1609-1617

Article dans une revue hal-01994996v1

Methodology for optimally sized centrifugal partition chromatography columns

Sébastien Chollet , Luc Marchal , Jérémy Meucci , Jean-Hugues Renault , Jack Legrand et al.

Journal of Chromatography A, 2015, 1388, pp.174 - 183. ⟨10.1016/j.chroma.2015.02.043⟩

Article dans une revue istex hal-01935725v1
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Fast Identification of Radical Scavengers from Securigera varia by Combining 13C-NMR-Based Dereplication to Bioactivity-Guided Fractionation

Pacôme Sientzoff , Jane Hubert , Coralie Janin , Laurence Voutquenne-Nazabadioko , Jean-Hugues Renault et al.

Molecules, 2015, 20 (8), pp.14970-14984. ⟨10.3390/molecules200814970⟩

Article dans une revue hal-01995000v1

Chemical characterization of natural cosmetic ingredients: New insights on identification strategies

Jean-Hugues Renault , Jane Hubert , Romain Reynaud , Jean-Marc Nuzillard , Sarah K. Oettl et al.

IFSCC Magazine, 2014

Article dans une revue hal-01994972v1

Dereplication of depsides from the lichen Pseudevernia furfuracea by centrifugal partition chromatography combined to 13C nuclear magnetic resonance pattern recognition

Sarah K. Oettl , Jane Hubert , Hermann Stuppner , Jean-Hugues Renault , Judith M. Rollinger et al.

Analytica Chimica Acta, 2014, 846, pp.60-67. ⟨10.1016/j.aca.2014.07.009⟩

Article dans une revue hal-01968801v1

Purification of antibiotics from the biocontrol agent Streptomyces anulatus S37 by centrifugal partition chromatography

Olivier Couillerot , Souad Loqman , Alix Toribio , Jane Hubert , Léa Gandner et al.

Journal of Chromatography B - Analytical Technologies in the Biomedical and Life Sciences, 2014, 944, pp.30-34. ⟨10.1016/j.jchromb.2013.11.008⟩

Article dans une revue hal-01968781v1

Two novel solvent system compositions for protected synthetic peptide purification by centrifugal partition chromatography

Nassima Amarouche , Matthieu Giraud , Luciano Forni , Alessandro Butte , F. Edwards et al.

Journal of Chromatography A, 2014, 1337, pp.155-161

Article dans une revue hal-01968791v1

Identification of Natural Metabolites in Mixture: A Pattern Recognition Strategy Based on 13 C NMR

Jane Hubert , Sylvain Purson , Mahmoud Hamzaoui , Nicolas Borie , Romain Reynaud et al.

Analytical Chemistry, 2014, 86 (6), pp.2955-2962. ⟨10.1021/ac403223f⟩

Article dans une revue hal-01968799v1

New biphasic solvent system based on cyclopentyl methyl ether for the purification of a non-polar synthetic peptide by pH-zone refining centrifugal partition chromatography

Nassima Amarouche , Leslie Boudesocque-Delaye , Nicolas Borie , Matthieu Giraud , Luciano Forni et al.

Journal of Separation Science, 2014, 37 (11), pp.1222-1228. ⟨10.1002/jssc.201300971⟩

Article dans une revue hal-01123362v1

Gradient elution method in centrifugal partition chromatography for the separation of a complex sophorolipid mixture obtained from Candida bombicola yeasts

Alexis Kotland , Imane Hadef , Jean-Hugues Renault , Mahmoud Hamzaoui , Agathe Martinez et al.

Journal of Separation Science, 2013, 36 (8), pp.1362-1369

Article dans une revue hal-01968741v1

Centrifugal partition extraction in the pH-zone-refining displacement mode: An efficient strategy for the screening and isolation of biologically active phenolic compounds

Mahmoud Hamzaoui , Jean-Hugues Renault , Romain Reynaud , Jane Hubert

Journal of Chromatography B - Analytical Technologies in the Biomedical and Life Sciences, 2013, 937, pp.7-12

Article dans une revue hal-01968748v1

Purification of a modified cyclosporine A by co-current centrifugal partition chromatography: Process development and intensification

Nassima Amarouche , Leslie Boudesocque-Delaye , Charlotte Sayagh , Matthieu Giraud , John Mcgarrity et al.

Journal of Chromatography A, 2013, 1311, pp.72 - 78. ⟨10.1016/j.chroma.2013.08.053⟩

Article dans une revue istex hal-01935738v1

Concentration and selective fractionation of an antihypertensive peptide from an alfalfa white proteins hydrolysate by mixed ion-exchange centrifugal partition chromatography

Leslie Boudesocque , Romain Kapel , Cedric Paris , Pascal Dhulster , Ivan Marc et al.

Journal of Chromatography B - Analytical Technologies in the Biomedical and Life Sciences, 2012, 905, pp.23-30. ⟨10.1016/j.jchromb.2012.07.034⟩

Article dans une revue istex hal-00777702v1

Oral Abstracts

Jean-Hugues Renault

Journal of Peptide Science, 2012, 18, pp.S29-S57

Article dans une revue hal-01968727v1

New perspectives for microbial glycolipid fractionation and purification processes

Jane Hubert , Karen Plé , Mahmoud Hamzaoui , Gladys Nuissier , Imane Hadef et al.

Comptes Rendus. Chimie, 2012, 15 (1), pp.18-28

Article dans une revue hal-01968714v1

Strong ion exchange in centrifugal partition extraction (SIX-CPE): Effect of partition cell design and dimensions on purification process efficiency

Mahmoud Hamzaoui , Jane Hubert , Romain Reynaud , Luc Marchal , Alain Foucault et al.

Journal of Chromatography A, 2012, 1247, pp.18-25. ⟨10.1016/j.chroma.2012.05.046⟩

Article dans une revue istex hal-01968718v1

Ion-exchange centrifugal partition chromatography: A methodological approach for peptide separation

Leslie Boudesocque-Delaye , Pedro Lameiras , Nassima Amarouche , Matthieu Giraud , Francesca Quattrini et al.

Journal of Chromatography A, 2012, 1236, pp.115-122. ⟨10.1016/j.chroma.2012.03.010⟩

Article dans une revue istex hal-01968716v1

Rhamnolipids Elicit Defense Responses and Induce Disease Resistance against Biotrophic, Hemibiotrophic, and Necrotrophic Pathogens That Require Different Signaling Pathways in Arabidopsis and Highlight a Central Role for Salicylic Acid

Lisa Sanchez , Barbara Courteaux , Jane Hubert , Serge Kauffmann , Jean-Hugues Renault et al.

Plant Physiology, 2012, 160 (3), pp.1630-1641. ⟨10.1104/pp.112.201913⟩

Article dans une revue hal-01968723v1

Glycerol and glycerol carbonate as ultraviscous solvents for mixture analysis by NMR.

Pedro Lameiras , Leslie Boudesocque , Zéphirin Mouloungui , Jean-Hugues Renault , Jean-Michel Wieruszeski et al.

Journal of Magnetic Resonance, 2011, 212 (1), pp.161-8. ⟨10.1016/j.jmr.2011.06.021⟩

Article dans une revue istex hal-00618281v1

Preparative isolation of glucosinolates from various edible plants by strong ion-exchange centrifugal partition chromatography

Alix Toribio , Leslie Boudesocque , Bernard Richard , Jean-Marc Nuzillard , Jean-Hugues Renault

Separation and Purification Technology, 2011, 83 (9), pp.15 - 22. ⟨10.1016/j.seppur.2011.07.001⟩

Article dans une revue istex hal-02646197v1

The stimulating adventure of KRN 7000.

Aline Banchet-Cadeddu , Eric Hénon , Manuel Dauchez , Jean-Hugues Renault , Fanny Monneaux et al.

Organic & Biomolecular Chemistry, 2011, 9, pp.3080-3104. ⟨10.1039/c0ob00975j⟩

Article dans une revue hal-00579731v1

Use of the NEO strategy (Nucleophilic addition/Epoxide Opening) for the synthesis of a new C-galactoside ester analogue of KRN 7000.

Aline Banchet-Cadeddu , Agathe Martinez , Stéphane Guillarme , Véronique Parietti , Fanny Monneaux et al.

Bioorganic and Medicinal Chemistry Letters, 2011, 21 (8), pp.2510-2514. ⟨10.1016/j.bmcl.2011.02.044⟩

Article dans une revue istex hal-00579736v1

Intensified extraction of ionized natural products by ion pair centrifugal partition extraction

Mahmoud Hamzaoui , Jane Hubert , Jamila Hadj-Salem , Bernard Richard , Dominique Harakat et al.

Journal of Chromatography A, 2011, 1218 (31), pp.5254 - 5262. ⟨10.1016/j.chroma.2011.06.018⟩

Article dans une revue istex hal-01935752v1

Study of a specific lignin model: gamma-oxidation and how it influences the hydrolysis efficiency of alcohol-aldehyde dehydrogenation copolymers

Florent F. Bouxin , Stéphanie Baumberger , Jean-Hugues J.-H. Renault , Patrice P. Dole

Bioresource Technology, 2011, 102 (10), pp.5567-5573. ⟨10.1016/j.biortech.2011.02.103⟩

Article dans une revue istex hal-01000537v1

Acidolysis of a lignin model: Investigation of heterogeneous catalysis using Montmorillonite clay

Florent Bouxin , Stéphanie Baumberger , Brigitte Pollet , Arnaud Haudrechy , Jean-Hugues Renault et al.

Bioresource Technology, 2010, 101 (2), pp.736-744. ⟨10.1016/j.biortech.2009.08.037⟩

Article dans une revue istex hal-01195444v1

Bacterial rhamnolipids are novel MAMPs conferring resistance to Botrytis cinerea in grapevine.

Varnier Al , L. Sanchez , P. Vatsa , Leslie Boudesocque-Delaye , A. Garcia-Brugger et al.

Plant, Cell and Environment, 2009, 32 (2), pp.178-193

Article dans une revue hal-00415108v1

Pilot-scale ion-exchange centrifugal partition chromatography: Purification of sinalbin from white mustard seeds

Alix Toribio , Jean-Marc Nuzillard , Benoît Pinel , Leslie Boudesocque-Delaye , Michel Lafosse et al.

Journal of Separation Science, 2009, 32 (11), pp.1801-1807. ⟨10.1002/jssc.200800651⟩

Article dans une revue istex hal-01968224v1

Bacterial rhamnolipids are novel MAMPs confering resistance to Botrytis cinerea in grapevine

A.L. Varnier , L. Sanchez , P. Vatsa , Leslie Boudesocque-Delaye , A. Garcia-Brugger et al.

Plant, Cell and Environment, 2009, 32, pp.178-193

Article dans une revue hal-00367324v1

Preparative purification of antiamyloidogenic stilbenoids from Vitis vinifera (Chardonnay) stems by centrifugal partition chromatography

N. Zga , Y. Papastamoulis , A. Toribio , T. Richard , J.C. Delaunay et al.

Journal of Chromatography B - Analytical Technologies in the Biomedical and Life Sciences, 2009, 877 (10), pp.1000-1004

Article dans une revue hal-01968690v1

Bacterial rhamnolipids are novel MAMPs conferring resistance to Botrytis cinerea in grapevine

Anne-Lise Varnier , Lisa Sanchez , Parul Vatsa , Leslie Boudesocque , Angela Garcia-Brugger et al.

Plant, Cell and Environment, 2009, 32 (2), pp.178-193. ⟨10.1111/j.1365-3040.2008.01911.x⟩

Article dans une revue hal-02666434v1

Large-scale purification of glucosinolates by strong ion-exchange centrifugal partition chromatography. From lab-scale CPC to 5L-pilot-scale FCPC

Jean-Hugues Renault , Jh Renault , A Toribio , L Lafosse , B Pinel et al.

Planta Medica, 2008, 74 (09), ⟨10.1016/j.chroma.2007.09.004⟩

Article dans une revue istex hal-01968215v1

Preparative isolation of huperzines A and B from Huperzia serrata by displacement centrifugal partition chromatography

Alix Toribio , Eldra Delannay , Bernard Richard , Monique Zèches , Jean-Marc Nuzillard et al.

Journal of Chromatography A, 2007, 1140, pp.101-106

Article dans une revue hal-00135672v1

Simultaneous presence of unsatuation and long alkyl chain at P'1 of ilomastat confers selectivity for gelatinase A (MMP-2) over gelatinase B (MMP-9= inhibition as shown by molecular modelling studies

Gauthier Moroy , Clément Denhez , Haquima El Mourabit , Alix Toribio , Alexandra Dassonville et al.

Bioorganic and Medicinal Chemistry, 2007, 15, pp.4753-4766

Article dans une revue hal-00157962v1

Novel seco-dibenzopyrrocoline alkaloid from Cryptocarya oubachensis

Alix Toribio , Aurélie Bonfils , Eldra Delannay , Elise Prost , Dominique Harakat et al.

Organic Letters, 2006, 8, pp.3825-3828. ⟨10.1021/ol061435f⟩

Article dans une revue hal-00134116v1

Large-scale isolation of anthocyanins from grapevine by strong ion-exchange centrifugal partition chromatography

Alix Toribio , Eldra Delannay , Jean-Marc Nuzillard , Monique Zèches , Bernard Richard et al.

Macromolecules and Secondary Metabolites of Grapevine and Wine, 2006, pp.247

Article dans une revue hal-00140236v1

Purification of the Main Ginsenosides from a French Crop of Panax Quinquefolium L.

L. Le Men-Olivier , Jean-Hugues Renault , P. Thepenier , J. Jacquier , M. Zeches-Hanrot et al.

Journal of Liquid Chromatography and Related Technologies, 2006, 18 (8), pp.1655-1662. ⟨10.1080/10826079508009302⟩

Article dans une revue hal-01968159v1

Multiple dual-mode centrifugal partition chromatography, a semi-continuous development mode for routine laboratory-scale purifications

Eldra Delannay , Alix Toribio , Leslie Boudesocque-Delaye , Jean-Marc Nuzillard , Monique Zeches-Hanrot et al.

Journal of Chromatography A, 2006, 1127 (1-2), pp.45-51. ⟨10.1016/j.chroma.2006.05.069⟩

Article dans une revue istex hal-01968206v1

Purification of Xanthohumol from Humulus lupulus by Centrifugal Partition Chromatography Using an Original Acetone Based Solvent Scale

Jean-Hugues Renault , Jean‐hugues Renault , Laurence Voutquenne , Catherine Caron , Monique Zeches‐hanrot et al.

Journal of Liquid Chromatography and Related Technologies, 2006, 29 (5), pp.761-771. ⟨10.1080/10826070500509330⟩

Article dans une revue hal-01968203v1

Preparative purification of Stilbenoids from Vitis vinifera (cv Chardonnay) by centrifugal partition chromatography

G. Papastamoulis , Alix Toribio , Agathe Martinez , Bernard Richard , Jean-Hugues Renault et al.

Macromolecules and Secondary Metabolites of Grapevine and Wine, 2006, pp.243

Article dans une revue hal-00140233v1

Separation of the Two Major Anthocyanins from Champagne Vintage By-Products by Gradient Elution Centrifugal Partition Chromatography

Jean-Hugues Renault , P. Thepenier , M. Zeches-Hanrot , P. Foucault

Journal of Liquid Chromatography and Related Technologies, 2006, 18 (8), pp.1663-1670. ⟨10.1080/10826079508009303⟩

Article dans une revue hal-01968160v1

Partitron 25, a Multi‐Purpose Industrial Centrifugal Partition Chromatograph: Rotor Design and Preliminary Results on Efficiency and Stationary Phase Retention

Jean-Hugues Renault , Rodolphe Margraff , Olivier Intes , Jean‐hugues Renault , Pierre Garret

Journal of Liquid Chromatography and Related Technologies, 2005, 28 (12-13), pp.1893-1902

Article dans une revue hal-01968202v1

Purification of Rosmarinic Acid by Strong Ion‐Exchange Centrifugal Partition Chromatography

Jean-Hugues Renault , Alexandre Maciuk , Alix Toribio , Monique Zeches‐hanrot , Jean-Marc Nuzillard et al.

Journal of Liquid Chromatography and Related Technologies, 2005, 28 (12-13), pp.1947-1957. ⟨10.1081/JLC-200063599⟩

Article dans une revue hal-01968200v1

Anion-Exchange Displacement Centrifugal Partition Chromatography

Alexandre Maciuk , Jean-Hugues Renault , Rodolphe Margraff , Philippe Trébuchet , Monique Zeches-Hanrot et al.

Analytical Chemistry, 2004, 76 (21), pp.6179-6186. ⟨10.1021/ac049499w⟩

Article dans une revue istex hal-01968198v1

Rational improvement of centrifugal partition chromatographic settings for the production of 5-n-alkylresorcinols from wheat bran lipid extract

Luc Marchal , Olivier Intes , Alain Foucault , Jack Legrand , Jean-Marc Nuzillard et al.

Journal of Chromatography A, 2003, 1005 (1-2), pp.51 - 62. ⟨10.1016/S0021-9673(03)00879-3⟩

Article dans une revue istex hal-01935758v1

Fractionation of low-molecular-mass heparin by centrifugal partition chromatography in the ion-exchange displacement mode

Olivier Intes , Jean-Hugues Renault , C Sinquin , Monique Zèches-Hanrot , Jean-Marc Nuzillard

Journal of Chromatography A, 2001, 918 (1), pp.47-57. ⟨10.1016/s0021-9673(01)00743-9⟩

Article dans une revue istex hal-01968185v1

Isolation of indole alkaloids from Catharanthus roseus by centrifugal partition chromatography in the pH-zone refining mode

Jean-Hugues Renault , Jean-Marc Nuzillard , Gaëlle Le Crouérour , Philippe Thépenier , Monique Zèches-Hanrot et al.

Journal of Chromatography A, 1999, 849 (2), pp.421-431. ⟨10.1016/S0021-9673(99)00495-1⟩

Article dans une revue istex hal-01968172v1

Preparative separation of anthocyanins by gradient elution centrifugal partition chromatography

Jean-Hugues Renault , Philippe Thépenier , Monique Zéches-Hanrot , Louisette Le Men-Olivier , André Durand et al.

Journal of Chromatography A, 1997, 763 (1-2), pp.345-352

Article dans une revue hal-01968169v1

Nuclear magnetic resonance monitoring of centrifugal partition chromatography in pH-zone-refining mode

Manfred Spraul , Ulrich Braumann , Jean-Hugues Renault , Philippe Thépenier , Jean-Marc Nuzillard

Journal of Chromatography A, 1997, 766 (1-2), pp.255-260. ⟨10.1016/S0021-9673(96)01038-2⟩

Article dans une revue istex hal-01968171v1

Dammarane saponins from Zizyphus lotus

Jean-Hugues Renault , Kamel Ghedira , Philippe Thepenier , Catherine Lavaud , Monique Zeches-Hanrot et al.

Phytochemistry, 1997, 44 (7), pp.1321-1327. ⟨10.1016/S0031-9422(96)00721-2⟩

Article dans une revue istex hal-01968167v1