Jean-Louis Delaunay

Publications

Article dans une revue (21)

ABCB4 disease-causing variants S242R, S346I, T437I and T1077M significantly impair its function and display differential sensitivity to potentiators Claire Madry,Ahmad Elbahnsi,Jean-Louis Delaunay,Anne Stary,Sylvie Lagayeet al. Scientific Reports, 2025, Online ahead of print. ⟨10.1038/s41598-025-28407-6⟩ Article dans une revue hal-05379985v1
Adipocyte-specific Mlkl knockout mitigates obesity-induced metabolic dysfunction by enhancing mitochondrial functions Juliette Tokgozoglu,Valeria Pistorio,Mirko Minini,Pierre-Antoine Soret,Virginie Steunouet al. Cell Death and Disease, 2025, 16 (1), pp.683. ⟨10.1038/s41419-025-08004-1⟩ Article dans une revue hal-05355442v1
Ivacaftor-Mediated Potentiation of ABCB4 Missense Mutations Affecting Critical Motifs of the NBDs: Repositioning Perspectives for Hepatobiliary Diseases Jean-Louis Delaunay,Ahmad Elbahnsi,Alix Bruneau,Claire Madry,Anne-Marie Durand-Schneideret al. International Journal of Molecular Sciences, 2023, 24, ⟨10.3390/ijms24021236⟩ Article dans une revue hal-04247765v1
MRCK-Alpha and Its Effector Myosin II Regulatory Light Chain Bind ABCB4 and Regulate Its Membrane Expression Alix Bruneau,Jean-Louis Delaunay,Anne-Marie Durand-Schneider,Virginie Vauthier,Amel Ben Saadet al. Cells, 2022, 11 (4), pp.617. ⟨10.3390/cells11040617⟩ Article dans une revue hal-03976740v1
MRCK-Alpha and Its Effector Myosin II Regulatory Light Chain Bind ABCB4 and Regulate Its Membrane Expression Alix Bruneau,Jean-Louis Delaunay,Anne-Marie Durand-Schneider,Virginie Vauthier,Amel Ben Saadet al. Cells, 2022, 11 (4), pp.617. ⟨10.3390/cells11040617⟩ Article dans une revue hal-03978788v1
The necroptosis-inducing pseudokinase mixed lineage kinase domain-like regulates the adipogenic differentiation of pre-adipocytes Julie Magusto,Carine Beaupe,Marta B Afonso,Martine Auclair,Jean-Louis Delaunayet al. iScience, 2022, 25 (10), pp.105166. ⟨10.1016/j.isci.2022.105166⟩ Article dans une revue hal-03810047v1
MRCK-Alpha and Its Effector Myosin II Regulatory Light Chain Bind ABCB4 and Regulate Its Membrane Expression Alix Bruneau,Jean-Louis Delaunay,Anne-Marie Durand-Schneider,Virginie Vauthier,Amel Ben Saadet al. Cells, 2022, 11 (4), pp.617. ⟨10.3390/cells11040617⟩ Article dans une revue hal-03976496v1
Effect of CFTR correctors on the traffic and the function of intracellularly retained ABCB4 variants Amel Ben Saad,Virginie Vauthier,Ágota Tóth,Angelika Janaszkiewicz,Anne-Marie Durand-Schneideret al. Liver International, 2021, 41 (6), pp.1344 - 1357. ⟨10.1111/liv.14839⟩ Article dans une revue hal-03263358v1
RAB10 Interacts with ABCB4 and Regulates Its Intracellular Traffic Amel Ben Saad,Virginie Vauthier,Martine Lapalus,Elodie Mareux,Evangéline Bennanaet al. International Journal of Molecular Sciences, 2021, 22 (13), pp.7087. ⟨10.3390/ijms22137087⟩ Article dans une revue hal-03278474v1
Molecular Regulation of Canalicular ABC Transporters Amel Ben Saad,Alix Bruneau,Elodie Mareux,Martine Lapalus,Jean-Louis Delaunayet al. International Journal of Molecular Sciences, 2021, 22 (4), pp.2113. ⟨10.3390/ijms22042113⟩ Article dans une revue hal-03163529v1
Functional rescue of an ABCB11 mutant by ivacaftor: A new targeted pharmacotherapy approach in bile salt export pump deficiency Elodie Mareux,Martine Lapalus,Rachida Amzal,Marion Almes,Tounsia Aït‐slimaneet al. Liver International, 2020, 40 (8), pp.1917-1925. ⟨10.1111/liv.14518⟩ Article dans une revue hal-04001111v1
Structural analogues of roscovitine rescue the intracellular traffic and the function of ER-retained ABCB4 variants in cell models Virginie Vauthier,Amel Ben Saad,Jonathan Elie,Nassima Oumata,Anne-Marie Durand-Schneideret al. Scientific Reports, 2019, 9 (1), pp.6653. ⟨10.1038/s41598-019-43111-y⟩ Article dans une revue hal-03976729v1
Inhibition of receptor-interacting protein kinase 1 improves experimental non-alcoholic fatty liver disease Amine Majdi,Lynda Aoudjehane,Vlad Ratziu,Tawhidul Islam,Marta Afonsoet al. Journal of Hepatology, 2019, ⟨10.1016/j.jhep.2019.11.008⟩ Article dans une revue hal-02400735v1
Comparison of in silico prediction and experimental assessment of ABCB4 variants identified in patients with biliary diseases Boudour Khabou,Anne-Marie Durand-Schneider,Jean-Louis Delaunay,Tounsia Aït-Slimane,Véronique Barbuet al. International Journal of Biochemistry and Cell Biology, 2017, ⟨10.1016/j.biocel.2017.05.028⟩ Article dans une revue hal-01535643v1
Functional defect of variants in the adenosine triphosphate–binding sites of ABCB4 and their rescue by the cystic fibrosis transmembrane conductance regulator potentiator, ivacaftor (VX‐770) Jean‐louis Delaunay,Alix Bruneau,Brice Hoffmann,Anne‐marie Durand‐schneider,Véronique Barbuet al. Hepatology, 2016, 65, pp.560 - 570. ⟨10.1002/hep.28929⟩ Article dans une revue hal-03976715v1
A PDZ-Like Motif in the Biliary Transporter ABCB4 Interacts with the Scaffold Protein EBP50 and Regulates ABCB4 Cell Surface Expression Quitterie Venot,Jean-Louis Delaunay,Laura Fouassier,Danièle Delautier,Thomas Falguièreset al. PLoS ONE, 2016, 11 (1), pp.e0146962. ⟨10.1371/journal.pone.0146962⟩ Article dans une revue hal-01274124v1
A functional classification of ABCB4 variations causing progressive familial intrahepatic cholestasis type 3 Jean-Louis Delaunay,Anne-Marie Durand-Schneider,Claire Dossier,Thomas Falguières,Julien Gautherotet al. Hepatology, 2015, 63 (5), pp.1620-1631. ⟨10.1002/hep.28300⟩ Article dans une revue hal-01258764v1
Phosphorylation of ABCB4 impacts its function: Insights from disease-causing mutations. Julien Gautherot,Danièle Delautier,Marie-Anne Maubert,Tounsia Aït-Slimane,Gérard Bolbachet al. Hepatology, 2014, 60 (2), pp.610-621 ⟨10.1002/hep.27170⟩ Article dans une revue hal-00978286v1
Differential solubilization of inner plasma membrane leaflet components by Lubrol WX and Triton X-100. Jean-Louis Delaunay,Breton Michelyne,Germain Trugnan,Michèle Maurice Biochimica et Biophysica Acta:Biomembranes, 2008, Volume 1778 (Issue 1), pp.Pages 105-112. ⟨10.1016/j.bbamem.2007.09.017⟩ Article dans une revue inserm-00418165v1
Differential detergent resistance of the apical and basolateral NPPases: relationship with polarized targeting. Jean-Louis Delaunay,Michelyne Breton,James W. Goding,Germain Trugnan,Michèle Maurice Journal of Cell Science, 2007, 120 (Pt 6), pp.1009-16. ⟨10.1242/jcs.002717⟩ Article dans une revue inserm-00418024v1
Prion infection of epithelial Rov cells is a polarized event Sophie Paquet,Elifsu Sabuncu,Jean-Louis Delaunay,Hubert H. Laude,Didier Vilette Journal of Virology, 2004, 78 (13), pp.7148-7152. ⟨10.1128/JVI.78.13.7148-7152.2004⟩ Article dans une revue hal-02676909v1

Thèse (1)

Rôle des microdomaines membranaires dans le ciblage apical de la nucléotide pyrophosphatase NPP3 dans les cellules MDCK Jean-Louis Delaunay Biologie cellulaire. Université Pierre et Marie Curie - Paris VI, 2007. Français. ⟨NNT : ⟩ Thèse tel-00429983v1