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JM
Jean-Louis Milan
12
Documents
Identifiants chercheurs
- jean-louis-milan
- 0000-0001-5191-3094
- IdRef : 124313736
Présentation
I have begun developing computational modelling of cytoskeleton dynamics to understand how the cells adapt their structure to their environment. I have succeed in proposing mechanisms of cell adhesion and cell migration guided by substrate shape. Based on these results of our models that reproduced observed phenomenon on static cellular environment, I have built the idea of upgrading the models into avatars of cell to develop strategies for tissue engineering based on in silico live predicting tool that a are able to guide cell functions into dynamic cellular environments.
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In silico analysis shows that dynamic changes in curvature guide cell migration over long distancesBiomechanics and Modeling in Mechanobiology, 2023, ⟨10.1007/s10237-023-01777-4⟩
Article dans une revue
hal-04258011v1
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Actomyosin, vimentin and LINC complex pull on osteosarcoma nuclei to deform on micropillar topographyBiomaterials, 2020, 234, pp.119746. ⟨10.1016/j.biomaterials.2019.119746⟩
Article dans une revue
hal-02525268v1
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A biophysical model for curvature-guided cell migrationBiophysical Journal, 2019, 117 (6), pp.1136-1144. ⟨10.1016/j.bpj.2019.07.022⟩
Article dans une revue
hal-02284526v1
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Curvotaxis directs cell migration through cell-scale curvature landscapesNature Communications, 2018, 9, ⟨10.1038/s41467-018-06494-6⟩
Article dans une revue
hal-01960533v1
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IN SILICO AVATARS OF CELLS TO PREDICT CELL MIGRATION ON TRAVELLING WAVES18th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering, CMBBE, Jun 2023, Paris, France
Communication dans un congrès
hal-04463371v1
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Avatars in silico pour prédire et piloter la migration des cellules sur des vagues de surfaceRITS (Recherche en Imagerie et Technologies pour la Santé) 2022, SFGBM (Société Française du Génie Biologique et Médical), May 2022, Brest, France
Communication dans un congrès
hal-04463374v1
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In silico avatars of cells to predict cell migration on travelling waves9th World Congress of Biomechanics, WCB, Jul 2022, Taipei, Thailand
Communication dans un congrès
hal-04463373v1
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Developing in silico avatars of cells to predict and drive cell migration on travelling wavesEuropean Congress of Biomechanics, Jun 2022, Porto, Portugal
Communication dans un congrès
hal-04463347v1
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Curvature-dependent mesenchymal cells and epithelial tissue migration and orientationInterface Biology of Implants IBI 2019, May 2019, Rostock, Germany
Communication dans un congrès
hal-02175659v1
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La curvotaxie ou comment la migration des cellules est dirigée par la courbure de leur environnementMatériaux 2018, Nov 2018, Strasbourg, France
Communication dans un congrès
hal-02188974v1
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How cells surf the waves? Curvotaxis directs migration trough cell-scale natural landscapesAmerican Society for Cell Biology C.1 Materials, Surfaces and Interfaces for Medical Applications and Health, Dec 2016, San Francisco, United States
Communication dans un congrès
hal-02175663v1
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Designing Optimal Scaffold Topographies to Promote Nucleus-Guided Mechanosensitive Cell Migration Using in Silico ModelsBilen Emek Abali; Ivan Giorgio. Developments and Novel Approaches in Biomechanics and Metamaterials, 132, Springer International Publishing, pp.199-216, 2020, Advanced Structured Materials, 978-3-030-50464-9. ⟨10.1007/978-3-030-50464-9_12⟩
Chapitre d'ouvrage
hal-03475182v1
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