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Jean-Louis Milan

8
Documents
Identifiants chercheurs

Présentation

I have begun developing computational modelling of cytoskeleton dynamics to understand how the cells adapt their structure to their environment. I have succeed in proposing mechanisms of cell adhesion and cell migration guided by substrate shape. Based on these results of our models that reproduced observed phenomenon on static cellular environment, I have built the idea of upgrading the models into avatars of cell to develop strategies for tissue engineering based on in silico live predicting tool that a are able to guide cell functions into dynamic cellular environments.

Publications

patrick-chabrand
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Local tissue effects and peri‐implant bone healing induced by implant surface treatment: an in vivo study in the sheep

Nicolas Rousseau , Ines Msolli , Patrick Chabrand , Arnaud Destainville , Olivier Richart
Journal of Periodontal Research, 2021, ⟨10.1111/jre.12878⟩
Article dans une revue hal-03192648v1
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Topology optimization and additive manufacturing: Comparison of conception methods using industrial codes

Yassine Saadlaoui , Jean-Louis Milan , Jean-Marie Rossi , Patrick Chabrand
Journal of Manufacturing Systems, 2017, 43 (1), pp.178-186. ⟨10.1016/j.jmsy.2017.03.006⟩
Article dans une revue hal-01691151v1
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In silico CDM model sheds light on force transmission in cell from focal adhesions to nucleus

Jean-Louis Milan , Ian Manifacier , Kevin M. Beussman , Sangyoon J. Han , Nathan J. Sniadecki
Journal of Biomechanics, 2016, 49 (13), pp.2625-2634. ⟨10.1016/j.jbiomech.2016.05.031⟩
Article dans une revue hal-01443843v1
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Computational Tension Mapping of Adherent Cells Based on Actin Imaging

Ian Manifacier , Jean-Louis Milan , Charlotte Jeanneau , Fanny Chmilewsky , Patrick Chabrand
PLoS ONE, 2016, 11 (1), ⟨10.1371/journal.pone.0146863⟩
Article dans une revue hal-01443844v1
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Computational model combined with in vitro experiments to analyse mechanotransduction during mesenchymal stem cell adhesion

Jean-Louis Milan , Sandrine Lavenus , Paul Pilet , Guy Louarn , Sylvie Wendling
eCells and Materials Journal, 2013, 25, pp.97-113. ⟨10.22203/eCM.v025a07⟩
Article dans une revue hal-02284008v1
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Divided medium-based model for analyzing the dynamic reorganization of the cytoskeleton during cell deformation

Jean-Louis Milan , Sylvie Wendling-Mansuy , Michel Jean , Patrick Chabrand
Biomechanics and Modeling in Mechanobiology, 2007, 6 (6), pp.373-390. ⟨10.1007/s10237-006-0057-7⟩
Article dans une revue hal-00475545v1

Granular medium to analyze cytoskeleton mechanics

Jean-Louis Milan , Sylvie Wendling Mansuy , Michel Jean , Patrick Chabrand
Cell Biomechanics Meeting, Sep 2005, Paris, France
Communication dans un congrès hal-00479997v1

Cytoskeleton dynamical behaviour approached by a granular tensegrity model.

Jean-Louis Milan , Sylvie Wendling Mansuy , Michel Jean , Patrick Chabrand
20th Congress of the International Society of Biomechanics, Jul 2005, Cleveland, United States
Communication dans un congrès hal-00479999v1