Jean-Loup Faulon
56
Documents
Presentation
**EDUCATION**
2007 Habilitation Chemistry, University of Strasbourg, France. Thesis title: The Signature Molecular Descriptor: Predicting Properties and Activities to Design Molecules and Biological Sequences.
1991 Ph.D. Computational Chemistry, Ecole des Mines, Paris, France. Thesis title: Prediction, Elucidation, and Molecular Modeling: Algorithms and Applications in Geochemistry.
1986 Master Computer Science, University of Paris VI, France. Thesis title: Hidden Surface Elimination.
1995 Engineering degree Computer Science, Institut d’Informatique d’Entreprise, Conservatoire National des Arts & Métiers, Paris, France.
1982 DEUG Chemistry, University of Dijon, France.
**RESEARCH, TEACHING AND ADMINISTRATIVE EXPERIENCE**
2015--- Senior Research Director (DR1) at MICALIS Institute. Head of the BioRetroSynth research team (~12 research staff).
2014--- Chair in Synthetic Biology and Systems Metabolic Engineering, School of Chemistry, The University of Manchester. SYNBIOCHEM cabinet member.
2010-2015 Director, Institute of Systems & Synthetic Biology (iSSB). iSSB is a CNRS research unit comprising 5 research teams, ~30 faculty and staff members and ~10 PhD students.
2010--- Head, Master in Systems & Synthtic Biology (mSSB). This master program has been ranked A+ by the French academic ranking agency (HCERES). The master has been running for 9 consecutive years and student have participated to the iGEM competition (gold medails in 2019, 2018, 2017, 2012, 2013, best model in 2012, best human practices in 2012 & 2013).
2009-2017 Consultant for Genopole ([www.genopole.fr](http://www.genopole.fr)). Advisor for the development of Synthetic Biology in Evry.
2008-2015 Full Professor, Biology Department, Évry University. Teaching Responsibility: bioinformatics, systems & synthetic biology, and metabolic engineering (undergraduate students first and 2nd-year graduate students).
Spring 2011 Visiting Scholar Institute for Pure and Applied Mathematics, UCLA, CA. Organized and chaired the long-term program « Navigating Chemical Compound Space for Materials and Bio Design ».
2007–2008 Director, Pretreatment Section, Deconstuction Division, Joint BioEnergy Institute, Emeryville, CA, USA. Research project: design of ionic liquids and cellulases for biofuel productions. Lead a group of 5 PhD staff scientists and post-docs (chemical engineers, analytical chemists, molecular biologists, and computational chemists).
2003–2008 Distinguished Member of the Systems Biology Dept., Sandia National Laboratories, Livermore, CA *(the distinguished scientist recognition is a peer-reviewed award given to the top 10% PhD employees).* Responsible of 9 research projects. Inference and dynamics of signaling and transcriptional networks (cf. MISL and GENET projects in funding sources lists). Prediction of protein-protein, enzyme-metabolite and drug-target interactions (GTL, PROTDESIGN and MLSC projects). Lead a group of 6 PhD staff scientists and post-docs in molecular biology, bioinformatics and computational biology.
1997–2003 Primary Member of Computational Biology Dept., Sandia National Laboratories *(25% of PhD staff scientists are primary members).* Research projects: structural biology (IBIG project), drug design and polymer design (MLSC, iQSAR and MICS projects). Lead a group of six polymer and materials staff scientists (ASCI project).
1995–1997 Senior Member of Computer-Aided Molecular Design group Sandia National Laboratories *(in 1995 I am one of the first non-US citizen to be hired by Sandia Labs on a tenured position).* Research projects: Structure and reaction network inference for hydrocarbon thermal cracking (funded by Chevron).
1993–1994 Research Associate in the Computer-Aided Molecular Design group at Sandia National Laboratories. Research: develop computational methods for molecular design and structure inference.
1991–1993 Post-doctoral Scientist in the Materials Science Dept. at Penn State Univ., PA, USA. Teaching: molecular modeling. Research: Molecular structure inference of natural products (lignin, humic substances).
1989–1991 Agent contractual, Ecole des Mines, Paris, France. Teaching: computer graphics, molecular modeling. Research: Molecular structure inference for petroleum precursors.
1985–1989 Adjunct Assistant Professor in Computer Science at the Conservatoire National Arts & Métiers, Paris, France. Teaching: computer graphics, computer systems, networks.
Publications
Large scale active-learning-guided exploration for in vitro protein production optimizationStructural Biology and Chemistry Department days, Jun 2019, Paris, France
Conference poster
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Enzyme discovery: Enzyme selection and pathway designMethods in Enzymology, 608, Elsevier Academic Press Inc., pp.25, 2018, Methods in Enzymology, 978-0-12-815148-8. ⟨10.1016/bs.mie.2018.04.005⟩
Book sections
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Extended metabolic space modelingSynthetic metabolic pathways, 1671, Springer, 394 p., 2017, Methods in Molecular Biology, 978-1-4939-7295-1
Book sections
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Retrosynthetic design of heterologous pathwaysSystems metabolic engineering, 985, Springer, 474 p., 2013, Methods in Molecular Biology, 978-1-62703-298-8
Book sections
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Retrosynthetic design of heterologous pathways 2013Systems Metabolic Engineering, 985, Humana Press, 2013, Methods in Molecular Biology, 978-1-62703-298-8. ⟨10.1007/978-1-62703-299-5_9⟩
Book sections
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Graphs: flexible representations of molecular structures and biological networksComputational Approaches in Cheminformatics and Bioinformatics, John Wiley and sons, 292 p., 2011, 978-0-470-38441-1. ⟨10.1002/9781118131411.ch6⟩
Book sections
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Artificial Metabolic Networks: enabling neural computation with metabolic networks2022
Preprints, Working Papers, ...
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IBISBA-FR : Une infrastructure en soutien au développement de la biotechnologie industrielle comme technologie clef pour l’industrie du futur et pour accompagner la bioéconomie et l’économie circulaireINRAE; CNRS; CEA; INSA Toulouse; Université de nantes; Aix-Marseille Université (AMU). 2021
Reports
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Synthèse du livre blanc des sciences de la vie du département des sciences de la vie de l'université Paris Saclay[0] 2015
Reports
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