Jean-Marie HEYDEL Professeur de Biochimie et de Biologie MoléculaireCirconscription Pharmacie UFR des Sciences de SantéUniversité de BourgogneFrance

Identifiants chercheurs

IdHAL :

jean-marie-heydel

ORCID :

0000-0002-6089-9922

IdRef :

059796138

VIAF :

216057262

ResearcherID :

http://www.researcherid.com/rid/E-5379-2017

Présentation

Jean-Marie Heydel currently works at the Centre des Sciences du Goût et de l’Alimentation (CSGA), University of Burgundy France. He is Professor in Biochemistry and molecular Biology at the University for Health Sciences in Dijon France. He has been continuously interested in Xenobiotic metabolism. Since 2005, he has led a working group investigating the function of XMEs in olfaction and taste. In the frame of transversal collaborations, he showed that XMEs are involved in the clearance of chemosensory molecules from the receptors environment and/or in the synthesis of chemosensory active metabolites both having significant consequences on perception (models: rodents, rabbit, drosophila, Human). His research interests currently focuse on xenobiotic metabolism at the brain interface, olfaction, peripheral physiology and biochemistry of smell and taste, animal and human volatilome.

Publications

Article dans une revue (57)

Dietary isothiocyanates inhibit the oxidative activity of salivary aldehyde dehydrogenase ALDH3A1 and modulate aroma release Valentin Boichot,Jeanne Chaloyard,Karine Gourrat,Jade Moreno,Jean-Michel Saliouet al. Food Chemistry, 2026, 508 (Part A), pp.148324. ⟨10.1016/j.foodchem.2026.148324⟩ Article dans une revue hal-05514870v1
A Human Oral Bacterial β-Glucosidase Involved in Aroma Release from Glycosides Mariam Muradova,Alena Proskura,Véronique Senty-Segault,Valentin Boichot,Victoria Ilinaet al. Journal of Agricultural and Food Chemistry, 2026, 74 (3), pp.2941-2950. ⟨10.1021/acs.jafc.5c13712⟩ Article dans une revue hal-05481558v1
Nasal xenobiotic metabolizing enzymes: at the crossroads of toxicity, detoxification, and olfaction Fabrice Neiers,Mathieu Schwartz,Nicole Kornbausch,Morgane Corda,Stephan Hackenberget al. Chemical Senses, 2025, 50, pp.bjaf063. ⟨10.1093/chemse/bjaf063⟩ Article dans une revue hal-05459238v1
The Ability of Basic and Glycosylated Proline-Rich Proteins to Protect Oral Enzymes from Polyphenol Inhibition Alena Proskura,Mariam Muradova,Nicolas Poirier,Victoria Ilina,Jeanne Chaloyardet al. Journal of Agricultural and Food Chemistry, 2025, 73 (33), pp.21000-21008. ⟨10.1021/acs.jafc.5c00821⟩ Article dans une revue hal-05203028v1
Odour learning concentration influences concentration range of conditioned response in newborn rabbits Gérard Coureaud,Marie-Sabelle Hjeij,Jeanne Serrano,Marc Thévenet,Samuel Garciaet al. Scientific Reports, 2025, 15 (1), pp.44682. ⟨10.1038/s41598-025-28326-6⟩ Article dans une revue hal-05457960v1
Two complementary analytical approaches to study odorant metabolism in the olfactory epithelium Nicole Kornbausch,Rémy Reynaud,Andrea Buettner,Maria Steinke,Thierry Thomas-Danguinet al. Food Chemistry, 2025, 496 (Part 2), pp.15. ⟨10.1016/j.foodchem.2025.146717⟩ Article dans une revue hal-05435560v1
Microbial β C-S Lyases: Enzymes with Multifaceted Roles in Flavor Generation Mathieu Schwartz,Nicolas Poirier,Jade Moreno,Alena Proskura,Mélanie Lelièvreet al. International Journal of Molecular Sciences, 2024, 25 (12), pp.6412. ⟨10.3390/ijms25126412⟩ Article dans une revue (article de synthèse) hal-04642563v2
Structural and Thermodynamic Insights into Dimerization Interfaces of Drosophila Glutathione Transferases Mathieu Schwartz,Nicolas Petiot,Jeanne Chaloyard,Véronique Senty-Segault,Frédéric Lirussiet al. Biomolecules, 2024, 14 (7), pp.758. ⟨10.3390/biom14070758⟩ Article dans une revue hal-04642588v1
Development of New Models of Oral Mucosa to Investigate the Impact of the Structure of Transmembrane Mucin-1 on the Mucosal Pellicle Formation and Its Physicochemical Properties Clément Nivet,Irma Custovic,Laure Avoscan,Floris Bikker,Aline Bonnotteet al. Biomedicines, 2024, 12 (1), pp.139. ⟨10.3390/biomedicines12010139⟩ Article dans une revue hal-04395339v1
Crystallization and Preliminary X-ray Diffraction Study of a Putative β-glycosidase from the Oral Bacteria &lt;i&gt;Prevotella sp.&lt;/i&gt; Mariam Muradova,Nicolas Poirier,Jade Moreno,Alena Proskura,F. Lirussiet al. Crystallography Reports, 2024, 69 (4), pp.507-512. ⟨10.1134/s1063774523601442⟩ Article dans une revue hal-04737369v1
Molecular and Cellular Characterization of the Glutathione Transferases Involved in the Olfactory Metabolism of the Mammary Pheromone Marie-Sabelle Hjeij,Franck Ménétrier,Isabelle Chauvel,Nicolas Poirier,Stéphane Fraichardet al. Journal of Agricultural and Food Chemistry, 2024, 72 (44), pp.24724-24735. ⟨10.1021/acs.jafc.4c07000⟩ Article dans une revue hal-04761763v1
Correction: The odorant metabolizing enzyme UGT2A1: Immunolocalization and impact of the modulation of its activity on the olfactory response F. Neiers,David Jarriault,Franck Menetrier,Philippe Faure,Loïc Briandet al. PLoS ONE, 2024, 19 (2), pp.e0299662. ⟨10.1371/journal.pone.0299662⟩ Article dans une revue hal-04666860v1
Characterization of a Human Respiratory Mucosa Model to Study Odorant Metabolism Jeanne Mérignac-Lacombe,Nicole Kornbausch,Rinu Sivarajan,Valentin Boichot,Kevin Berget al. Journal of Agricultural and Food Chemistry, 2024, 72 (22), pp.12696-12706. ⟨10.1021/acs.jafc.4c00752⟩ Article dans une revue hal-04665602v1
&lt;i&gt;Rattus norvegicus&lt;/i&gt; Glutathione Transferase Omega 1 Localization in Oral Tissues and Interactions with Food Phytochemicals Nicolas Poirier,Franck Ménétrier,Jade Moreno,Valentin Boichot,Jean-Marie Heydelet al. Journal of Agricultural and Food Chemistry, 2024, 72 (11), pp.5887-5897. ⟨10.1021/acs.jafc.4c00483⟩ Article dans une revue hal-04493038v1
Role of Insect and Mammal Glutathione Transferases in Chemoperception Mathieu Schwartz,Valentin Boichot,Stéphane Fraichard,Mariam Muradova,Patrick Senetet al. Biomolecules, 2023, 13 (2), pp.322. ⟨10.3390/biom13020322⟩ Article dans une revue hal-04011738v1
Unlocking Flavor Potential Using Microbial β-Glucosidases in Food Processing Mariam Muradova,Alena Proskura,Francis Canon,Irina Aleksandrova,Mathieu Schwartzet al. Foods, 2023, 12 (24), pp.4484. ⟨10.3390/foods12244484⟩ Article dans une revue hal-04395322v1
Drosophila Free-Flight Odor Tracking is Altered in a Sex-Specific Manner By Preimaginal Sensory Exposure Vincent Tolassy,Laurie Cazalé-Debat,Benjamin Houot,Rémy Reynaud,Jean-Marie Heydelet al. Journal of Chemical Ecology, 2023, 49 (3-4), pp.179-194. ⟨10.1007/s10886-023-01416-3⟩ Article dans une revue hal-04080541v1
Characterization of human oxidoreductases involved in aldehyde odorant metabolism Valentin Boichot,Franck Menetrier,Jean-Michel Saliou,Frederic Lirussi,Francis Canonet al. Scientific Reports, 2023, 13 (1), pp.4876. ⟨10.1038/s41598-023-31769-4⟩ Article dans une revue hal-04080823v1
Activity, Localization and Regulation of Odorant Metabolizing Enzymes in the Newborn Rabbit: New Highlights on the Mammary Pheromone Nasal Metabolism Marie-Sabelle Hjeij,Franck Ménétrier,Stéphane Fraichard,Isabelle Chauvel,Gwenaelle Steyaertet al. Chemical Senses, 2023, 48, pp.bjad029.25 Article dans une revue hal-04473191v1
Impact of aldehyde dehydrogenases and aldo-keto reductases in human olfactory peri-receptor events Valentin Boichot,Franck Ménétrier,Jean Michel Saliou,Frédéric Lirussi,Francis Canonet al. Chemical Senses, 2023, 48, pp.bjad029.01 Article dans une revue hal-04473519v1
Perspectives on Nasal Odorant Metabolism Research Nicole Kornbausch,Jeanne Mérignac-Lacombe,F. Neiers,Thierry Thomas-Danguin,Jean-Marie Heydelet al. Journal of Agricultural and Food Chemistry, 2023, 71 (44), pp.16488-16492. ⟨10.1021/acs.jafc.3c04662⟩ Article dans une revue hal-04272219v1
Nasal Odorant Competitive Metabolism Is Involved in the Human Olfactory Process Aline Robert-Hazotte,Philippe Faure,Franck Ménétrier,Mireille Folia,Mathieu Schwartzet al. Journal of Agricultural and Food Chemistry, 2022, 70 (27), pp.8385-8394. ⟨10.1021/acs.jafc.2c02720⟩ Article dans une revue hal-03728119v1
The role of perireceptor events in flavor perception Valentin Boichot,Mariam Muradova,Clément Nivet,Alena Proskura,Jean-Marie Heydelet al. Frontiers in Food Science and Technology, 2022, 2, pp.989291. ⟨10.3389/frfst.2022.989291⟩ Article dans une revue hal-03934249v1
Odorant Metabolism in Humans Nicole Kornbausch,Marcel Debong,Andrea Buettner,Jean-Marie Heydel,Helene Loos Angewandte Chemie International Edition, 2022, 61 (35), pp.e202202866. ⟨10.1002/anie.202202866⟩ Article dans une revue (article de synthèse) hal-03744098v1
Role of human salivary enzymes in bitter taste perception Mathieu Schwartz,Hélène Brignot,Gilles Feron,Thomas Hummel,Yunmeng Zhuet al. Food Chemistry, 2022, 386, pp.132798. ⟨10.1016/j.foodchem.2022.132798⟩ Article dans une revue hal-03712655v1
Oral enzymatic detoxification system: Insights obtained from proteome analysis to understand its potential impact on aroma metabolization Mathieu Schwartz,F. Neiers,Jean-Philippe Charles,Jean-Marie Heydel,Carolina Muñoz-Gonzálezet al. Comprehensive Reviews in Food Science and Food Safety, 2021, 20 (6), pp.5516-5547. ⟨10.1111/1541-4337.12857⟩ Article dans une revue hal-03388853v1
The odorant metabolizing enzyme UGT2A1: Immunolocalization and impact of the modulation of its activity on the olfactory response Fabrice Neiers,David Jarriault,Franck Menetrier,Loïc Briand,Jean-Marie Heydel PLoS ONE, 2021, 16 (3), pp.e0249029. ⟨10.1371/journal.pone.0249029⟩ Article dans une revue hal-03191804v1
Interactions between odorants and glutathione transferases in the human olfactory cleft Mathieu Schwartz,Franck Menetrier,Jean-Marie Heydel,Evelyne Chavanne,Philippe Faureet al. Chemical Senses, 2020, 45 (8), pp.645-654. ⟨10.1093/chemse/bjaa055⟩ Article dans une revue hal-02917092v1
Modulation of sex pheromone discrimination by a UDP-glycosyltransferase in Drosophila melanogaster Stéphane Fraichard,Arièle Legendre,Philippe Lucas,Isabelle Chauvel,Philippe Faureet al. Genes, 2020, 11 (3), pp.237. ⟨10.3390/genes11030237⟩ Article dans une revue hal-02498984v1
Publisher Correction: Nasal mucus glutathione transferase activity and impact on olfactory perception and neonatal behavior Aline Robert Hazotte,Philippe Faure,Fabrice Neiers,Catherine Potin,Yves Arturet al. Scientific Reports, 2019, 9 (1), pp.8111. ⟨10.1038/s41598-019-44135-0⟩ Article dans une revue hal-02623163v1
Ex vivo real-time monitoring of volatile metabolites resulting from nasal odorant metabolism Aline Robert-Hazotte,Rachel Schoumacker,Etienne Semon,Loïc Briand,Elisabeth Guichardet al. Scientific Reports, 2019, 9 (1), pp.2492. ⟨10.1038/s41598-019-39404-x⟩ Article dans une revue hal-02621806v1
Nasal mucus glutathione transferase activity and impact on olfactory perception and neonatal behavior Aline Robert-Hazotte,Philippe Faure,Fabrice Neiers,Catherine Potin,Yves Arturet al. Scientific Reports, 2019, 9 (1), pp.3104. ⟨10.1038/s41598-019-39495-6⟩ Article dans une revue hal-02106638v1
Publisher Correction: Ex vivo real-time monitoring of volatile metabolites resulting from nasal odorant metabolism Aline Robert-Hazotte,Rachel Schoumacker,Etienne Semon,Loïc Briand,Elisabeth Guichardet al. Scientific Reports, 2019, 9 (1), pp.8112. ⟨10.1038/s41598-019-44134-1⟩ Article dans une revue hal-02620777v1
Nasal odorant metabolism: enzymes, activity and function in olfaction Jean-Marie Heydel,Philippe Faure,Fabrice Neiers Drug Metabolism Reviews, 2019, 51 (2), pp.224-245. ⟨10.1080/03602532.2019.1632890⟩ Article dans une revue (article de synthèse) hal-02618624v1
P-glycoprotein 1 affects chemoactivities of resveratrol against human colorectal cancer cells Virginie Aires,Didier J. Colin,Agnès Doreau,Attilio Di Pietro,Jean-Marie Heydelet al. Nutrients, 2019, 11 (9), pp.2098. ⟨10.3390/nu11092098⟩ Article dans une revue hal-02627290v1
Characterization of rat glutathione transferases in olfactory epithelium and mucus Jean-Marie Heydel,Franck Menetrier,Christine Belloir,Francis Canon,Philippe Faureet al. PLoS ONE, 2019, 14 (7), pp.e0220259. ⟨10.1371/journal.pone.0220259⟩ Article dans une revue inserm-02264544v1
Characterization of a Drosophila glutathione transferase involved in isothiocyanate detoxification Daniel Gonzalez,Stéphane Fraichard,Paul Grassein,Patrice Delarue,Patrick Senetet al. Insect Biochemistry and Molecular Biology, 2018, 95, pp.33-43. ⟨10.1016/j.ibmb.2018.03.004⟩ Article dans une revue hal-02383021v1
Data on the expression of GSTE1 and GSTE7 in Drosophila chemosensory organs after isothiocyanate exposure Stéphane Fraichard,Daniel Gonzalez,Paul Grassein,Patrice Delarue,Patrick Senetet al. Data in Brief, 2018, 20, pp.254-257. ⟨10.1016/j.dib.2018.07.062⟩ Article dans une revue (data paper) hal-02624391v1
Odorant-odorant metabolic interaction, a novel actor in olfactory perception and behavioral responsiveness Hassan-Ismail Hanser,Philippe Faure,Aline Robert-Hazotte,Yves Artur,Patricia Duchamp-Viretet al. Scientific Reports, 2017, 7 (1), pp.10219. ⟨10.1038/s41598-017-10080-z⟩ Article dans une revue inserm-01599429v1
Real-time monitoring of the metabolic capacity of ex vivo rat olfactory mucosa by proton transfer reaction mass spectrometry (PTR-MS) Rachel Schoumacker,Aline Robert-Hazotte,Jean-Marie Heydel,Philippe Faure,Jean-Luc Le Quéré Analytical and Bioanalytical Chemistry, 2016, 408 (6), pp.1539 - 1543. ⟨10.1007/s00216-015-9289-7⟩ Article dans une revue hal-01399902v1
Odorant Metabolism Analysis by an Automated Ex Vivo Headspace Gas-Chromatography Method Philippe Faure,Arièle Legendre,Hassan-Ismail Hanser,Isabelle Andriot,Yves Arturet al. Chemical Senses, 2016, 41 (1), pp.15 - 23. ⟨10.1093/chemse/bjv055⟩ Article dans une revue hal-01398990v1
A self-inducible heterologous protein expression system in Escherichia coli Loïc Briand,Guillaume Marcion,Alexandre Kriznik,Jean-Marie Heydel,Yves Arturet al. Scientific Reports, 2016, 6, pp.33037. ⟨10.1038/srep33037⟩ Article dans une revue hal-01392201v1
Cytochrome P450-dependent metabolism of caffeine in [i]Drosophila melanogaster[/i] Alexandra Coelho,Stéphane Fraichard,Gaëlle Le Goff,Philippe Faure,Yves Arturet al. PLoS ONE, 2015, 10 (2), ⟨10.1371/journal.pone.0117328⟩ Article dans une revue hal-01212004v1
When the nose must remain responsive: glutathione conjugation of the mammary pheromone in the newborn rabbit Arièle Legendre,Philippe Faure,Hélène Tiesset,Catherine Potin,Ingrid Jakobet al. Chemical Senses, 2014, 39 (5), pp.425 - 437. ⟨10.1093/chemse/bju013⟩ Article dans une revue hal-01222435v1
Odorant-binding proteins and xenobiotic metabolizing enzymes: implications in olfactory perireceptor events. Jean-Marie Heydel,Alexandra Coelho,Nicolas Thiebaud,Arièle Legendre,Anne-Marie Le Bonet al. The Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology, 2013, 296 (9), pp.1333-45. ⟨10.1002/ar.22735⟩ Article dans une revue hal-00866526v1
Odorant metabolism catalyzed by olfactory mucosal enzymes influences peripheral olfactory responses in rats. Nicolas Thiebaud,Stéphanie Veloso da Silva,Ingrid Jakob,Gilles Sicard,Joëlle Chevalieret al. PLoS ONE, 2013, 8 (3), pp.e59547. ⟨10.1371/journal.pone.0059547⟩ Article dans une revue hal-00818303v1
Validation of a set of reference genes to study response to herbicide stress in grasses. Cécile Petit,Fanny Pernin,Jean-Marie Heydel,Christophe Délye BMC Research Notes, 2012, 5, pp.18. ⟨10.1186/1756-0500-5-18⟩ Article dans une revue hal-00782674v1
Effect of oxidative stress on UDP-glucuronosyltransferases in rat astrocytes. Daniela Gradinaru,Anne-Laure Minn,Yves Artur,Alain Minn,Jean-Marie Heydel Toxicology Letters, 2012, 213 (3), pp.316-24. ⟨10.1016/j.toxlet.2012.07.014⟩ Article dans une revue istex hal-00767137v1
Ciprofibrate regulation of rat hepatic bilirubin glucuronidation and UDP-glucuronosyltransferases expression. Jean-Marie Heydel,Philippe Garnier,Philippe Faure,Yves Artur European journal of drug metabolism and pharmacokinetics, 2012, 37 (4), pp.233-40. ⟨10.1007/s13318-012-0091-z⟩ Article dans une revue hal-00767156v1
Expression and differential localization of xenobiotic transporters in the rat olfactory neuro-epithelium. Nicolas Thiebaud,Franck Ménétrier,Christine Belloir,Anne-Laure Minn,Fabrice Neierset al. Neuroscience Letters, 2011, 505 (2), pp.180-5. ⟨10.1016/j.neulet.2011.10.018⟩ Article dans une revue istex hal-00755577v1
Effects of typical inducers on olfactory xenobiotic-metabolizing enzyme, transporter, and transcription factor expression in rats. Nicolas Thiebaud,Maud Sigoillot,Joëlle Chevalier,Yves Artur,Jean-Marie Heydelet al. Drug Metabolism and Disposition, 2010, 38 (10), pp.1865-75. ⟨10.1124/dmd.110.035014⟩ Article dans une revue hal-00745700v1
UDP-glucuronosyltransferases (UGTs) in neuro-olfactory tissues: expression, regulation, and function. Jean-Marie Heydel,Elzbieta J Holsztynska,Arièle Legendre,Nicolas Thiebaud,Yves Arturet al. Drug Metabolism Reviews, 2010, 42 (1), pp.74-97. ⟨10.3109/03602530903208363⟩ Article dans une revue hal-00745697v1
Drug metabolizing enzyme expression in rat choroid plexus: effects of in vivo xenobiotics treatment Daniela Gradinaru,Anne-Laure Minn,Yves Artur,Alain Minn,Jean-Marie Heydel Archives of Toxicology, 2009, 83 (6), pp.581-586. ⟨10.1007/s00204-008-0386-7⟩ Article dans une revue istex hal-02663406v1
Effects of endocrine disruptors on genes associated with 17 beta-estradiol metabolism and excretion Nathalie Hanet,Allan Lancon,Dominique Delmas,Brigitte Jannin,Marie-Christine Chagnonet al. Steroids, 2008, 73 (12), pp.1242-1251. ⟨10.1016/j.steroids.2008.06.005⟩ Article dans une revue istex hal-02662141v1
Effect of Retinoids on UDP-Glucuronosyltransferase 2B7 mRNA Expression in Caco-2 Cells Yang Lu,Stacie Bratton,Jean-Marie Heydel,Anna Radominska-Panndya Drug Metabolism and Pharmacokinetics, 2008, 23 (5), pp.364-372 Article dans une revue hal-02657038v1
Resveratrol in human hepatoma HepG2 cells: metabolism and inducibility of detoxifying enzymes. Allan Lançon,Nathalie Hanet,Brigitte Jannin,Dominique Delmas,Jean-Marie Heydelet al. Drug Metabolism and Disposition, 2007, 35 (5), pp.699-703. ⟨10.1124/dmd.106.013664⟩ Article dans une revue hal-00259260v1
Induction of cytochrome P450 and/or detoxication enzymes by various extracts or rosemary: description of specific patterns P. Debersac,Jean-Marie Heydel,Marie Josèphe Amiot,Hervé Goudonnet,Yves Arturet al. Food and Chemical Toxicology, 2001, 39 (9), pp.907-918 Article dans une revue hal-02682157v1

Communication dans un congrès (31)

Methods for evaluating astringency in food products Mélanie Lelièvre,Mariam Muradova,Mathieu Schwartz,Francis Canon,Alena Proskuraet al. FLAVOURsome Satellite Event at Food Oral Processing Conference, May 2025, Valencia, Spain Communication dans un congrès hal-05459704v1
The oral microbiome and its role in sensory perception and food choices Mariam Muradova,Mathieu Schwartz,Francis Canon,Franck Ménétrier,Jeanne Chaloyardet al. FLAVOURsome and FlavourFerm - COST Workshop "Flavour frontiers: Science, Culture and Innovation in Fermentation", Jun 2025, Brussels (Belgium), Belgium Communication dans un congrès hal-05459644v1
The role of the oral microbiome in sensory perception Mariam Muradova,Mathieu Schwartz,Francis Canon,Franck Ménétrier,Jeanne Chaloyardet al. The FRANCE-JAPAN JOINT SYMPOSIUM 2025 in KUMAMOTO "Advancing France-Japan Collaboration in Food and Agritech", Oct 2025, Kumamoto, Japan Communication dans un congrès hal-05459672v1
Molecules of the flavor F. Neiers,Mathieu Schwartz,Jean-Marie Heydel,Valentin Boichot,Francis Canon IATA Conference, Instituto de Agroquímica y Tecnología de Alimentos, Jun 2022, Valence, Spain Communication dans un congrès hal-03827290v1
Flavour from the molecules to the behaviour F. Neiers,Mathieu Schwartz,Jean-Marie Heydel,Boichot Valentin,Francis Canon Food Science Meeting, May 2022, Valence, Spain Communication dans un congrès hal-03828980v1
Role of human metabolizing enzymes in food perception Valentin Boichot,Franck Ménétrier,Jean-Marie Heydel,Francis Canon,Mathieu Schwartzet al. FORTHEM Food Science Lab Workshop, Mar 2022, Palermo, Italy Communication dans un congrès hal-03611500v1
Function of nasal odorant metabolism in vertebrate olfaction Jean-Marie Heydel Conférence ISIPCA, Jan 2021, Paris, France Communication dans un congrès hal-03179876v1
How odorant metabolizing enzymes shape odor perception? Jean-Marie Heydel The International Symposium on Olfaction and Taste (ISOT), Aug 2020, virtual congress, United States Communication dans un congrès hal-03053514v1
Implication des enzymes dans la perception chimio-sensorielle : une piste dans les troubles olfacto-gustatifs induits par des xénobiotiques ? Marie-Chantal Canivenc-Lavier,Jean-Marie Heydel,Franck Ménétrier,Christine Belloir,Philippe Faureet al. Journées Nacre, Dec 2019, Paris, France Communication dans un congrès hal-02944510v1
Les systèmes de détoxification dans le signal olfactif Jean-Marie Heydel Colloque de l'ARET (association pour la recherche en toxicologie), May 2018, Dijon, France Communication dans un congrès hal-02785733v1
Function of nasal odorant metabolism in mammalian olfaction Jean-Marie Heydel 40. annual meeting - association for chemoreception sciences (AChemS), Apr 2018, Bonita Springs, Florida, United States. 2 p Communication dans un congrès hal-02735549v1
Drosophila melanogaster glutathione transferase overexpressed in the sensory organs after exposure to bitter molecules in food Daniel Gonzalez,Stéphane Fraichard,Jean-François Ferveur,Yves Artur,Loïc Briandet al. The 26. Annual Meeting of the European-Chemoreception-Research-Organization (ECRO), Marika Kapsimali, Sep 2016, Dijon, France. pp.E45-E46 Communication dans un congrès hal-02912249v1
Aroma volatile odorous metabolites at olfactory mucosa level evidenced by in vitro and in vitro PTS-MS studies Rachel Schoumacker,Aline Robert Hazotte,Etienne Semon,Elisabeth Guichard,Jean-Marie Heydelet al. 26. annual meeting of the european-chemoreception-research-organization (ECRO), European Chemoreception Research Organization (ECRO). INT., Sep 2016, Dijon, France. ⟨10.1093/chemse/bjw120⟩ Communication dans un congrès hal-01595518v1
New insights in vertebrate 'biotransfolfaction Jean-Marie Heydel,Aline Robert Hazotte,Rachel Schoumacker,Hassan-Ismail Hanser,Fabrice Neierset al. The 26. Annual Meeting of the European-Chemoreception-Research-Organization (ECRO), Sep 2016, Dijon, France. pp.E-18-E19 Communication dans un congrès hal-02912358v1
Odorant-odorant metabolic competitions: ex vivo inhibition of the mammary pheromone catabolism Aline Robert Hazotte,Gérard Coureaud,Hassan-Ismail Hanser,Rachel Schoumacker,Etienne Sémonet al. 26th Annual Meeting of the European-Chemoreception-Research-Organization (ECRO), European Chemorecept Res Org, Sep 2016, Athènes, Greece. pp.E50-E51 Communication dans un congrès hal-01565748v1
New insights in vertebrate &lt;&lt; biotransfolfaction &gt;&gt; Jean-Marie Heydel,Aline Robert Hazotte,Rachel Schoumacker,Hassan-Ismail Hanser,Fabrice Neierset al. 26th Annual Meeting of the European-Chemoreception-Research-Organization (ECRO), European Chemorecept Res Org, Sep 2016, Athènes, Greece Communication dans un congrès hal-01565918v1
Aroma volatile metabolites at olfactory mucosa level evidenced by in vitro PTR-Tof-MS studies Rachel Schoumacker,Aline Robert Hazotte,Etienne Sémon,Jean-Marie Heydel,Philippe Faureet al. 7. International conference on proton transfer reaction mass spectrometry and its applications, Armin Hansel and Jürgen Dunkl, Feb 2016, Obergurgl, Austria Communication dans un congrès hal-01515660v1
Interactions of human nasal glutathione transferases with odorants. Fabrice Neiers,Jean-Marie Heydel,Loïc Briand 25th Annual Meeting of the European-Chemoreception-Research-Organization (ECRO), European Chemorecept Res Org, Sep 2015, Istanbul, Turkey. pp.422-422, ⟨10.1093/chemse/bjw019⟩ Communication dans un congrès hal-01398373v1
Real time monitoring of the metabolic capacity of ex-vivo rat olfactory mucosa by on-line PTR-MS Rachel Schoumacker,Aline Robert Hazotte,Etienne Semon,Jean-Marie Heydel,Philippe Faureet al. 11. Wartburg symposium on flavor chemistry & biology, Jun 2016, Eisenach, Germany Communication dans un congrès hal-01581528v1
Métabolisme périphérique des odorants : arrêt ou modulation du signal olfactif ? Jean-Marie Heydel 1. réunion du GDR (Groupe De Réflexion) Odorant Odeur Olfaction, Centre National de la Recherche Scientifique (CNRS). FRA., Oct 2015, Dijon, France Communication dans un congrès hal-01594081v1
Caffeine metabolism in &lt;em&gt;Drosophila melanogaster&lt;/em&gt; Stéphane Fraichard,Alexandra Coelho,Philippe Faure,Jean-François Ferveur,Jean-Marie Heydel 24. Annual Meeting of the European-Chemoreception-Research-Organization (ECRO), 2015, Oxford, United Kingdom Communication dans un congrès hal-02741361v1
Role of CYP6d5 in the metabolism and the sensory perception of caffeine in &lt;em&gt;Drosophila melanogaster&lt;/em&gt; Alexandra Coelho,Stéphane Fraichard,Philippe Faure,Jean-François Ferveur,Jean-Marie Heydel 24. Annual Meeting of the European-Chemoreception-Research-Organization (ECRO), Sep 2014, Dijon, France Communication dans un congrès hal-02742181v1
Real time monitoring of the metabolic capacity of ex-vivo rat olfactory mucosa by on-line PTR-MS Rachel Schoumacker,Aline Robert Hazotte,Jean-Marie Heydel,Philippe Faure,Etienne Semonet al. Congrès français de Spectrométrie de Masse et d'Analyse Protéomique (SMAP 2015), Sep 2015, Ajaccio, Corse, France. 1 p Communication dans un congrès hal-01580721v1
Oxidative stress and xenobiotic detoxification enzymes in rat astrocytes: Correlations with brain aging Daniela Gradinaru,Anne-Laure Minn,Yves Artur,Jean-Marie Heydel 11th International Symposium on the Neurobiology and Neuroendocrinology of Aging, Jul 2012, Bregenz, Austria. pp.688-688, ⟨10.1016/j.exger.2013.05.021⟩ Communication dans un congrès istex hal-00879048v1
Role of xenobiotic metabolizing enzymes in the perception of caffeine in Drosophila melanogaster Alexandra Coelho,Stéphane Fraichard,Philippe Faure,Jean-François Ferveur,Jean-Marie Heydel 16th International Symposium on Olfaction and Taste (ISOT), Jun 2012, Stockholm, Sweden Communication dans un congrès hal-00746002v1
Role of CYTOCHROME p450 in the perception of caffeine in Drosophila melanogaster Alexandra Coelho,Stéphane Fraichard,Philippe Faure,Jean-Marie Heydel 25th French Drosophila Conference, Oct 2011, Lyon, France Communication dans un congrès hal-00745782v1
Role of CYTOCHROME p450 in the perception of caffeine in Drosophila melanogaster Alexandra Coelho,Stéphane Fraichard,Philippe Faure,Jean-Marie Heydel The 21st Congress of the Eropean Chemoreception Research Organisation (ECRO), Sep 2011, Manchester, United Kingdom. 1 p Communication dans un congrès hal-00745790v1
Olfactory xenobiotic metabolizing enzymes have an impact on the stimulating properties of some odorants Nicolas Thiebaud,Stéphanie Veloso da Silva,Ingrid Jakob,Gilles Sicard,Yves Arturet al. The 32nd Annual Meeting - Association for Chemoreception Sciences (AChemS), Apr 2010, St Pete Beach, Florida, United States Communication dans un congrès hal-00816544v1
Activity and expression of drug metabolizing enzymes in olfactory mucosa of rats treated by hepatic inducers Nicolas Thiebaud,Maud M. Sigoillot,Joelle Chevallier,Yves Artur,Jean-Marie Heydelet al. List of Abstracts from the 18. Congress of European Chemoreception Research Organization, ECRO–2008, Sep 2008, Ljubljana, Slovenia Communication dans un congrès hal-02822861v1
Glutathione conjugation of the rabbit mammary pheromone 2-methylbut-2-enal Arièle Legendre,Hélène Tiesset,Ingrid Jacob,Anne-Marie Le Bon,Gérard Coureaudet al. 18. Congress of European Chemoreception Research Organization, ECRO–2008, Sep 2008, Portoroz, Slovenia Communication dans un congrès hal-02819467v1
Biotransformation of odorants modifies the olfactory signal Nicolas Thiebaud,Stéphanie Veloso da Silva,Ingrid Jakob,Gilles Gs Sicard,Yves Arturet al. 31. Annual meeting - Association for chemoreception sciences (Achems), Apr 2009, Sarasota, Floride, United States. 1 p Communication dans un congrès hal-02754927v1

Poster de conférence (18)

Role of oral bacterial glycosidases in human flavor perception Mariam Muradova,Alena Proskura,Nicolas Poirier,Francis Canon,Jean-Marie Heydelet al. The International Symposium on Olfaction and Taste (ISOT), Jun 2024, Reykjavík, Iceland Poster de conférence hal-04771642v1
Purification and functional characterization of three human salivary proline-rich proteins involved in astringency Alena Proskura,Mariam Muradova,Nicolas Poirier,Mathieu Schwartz,Francis Canonet al. The International Symposium on Olfaction and Taste (ISOT), Jun 2024, Reykjavík, Iceland Poster de conférence hal-04771592v1
Characterization of the glutathione transferases involved in the olfactory metabolism of the mammary pheromone Marie-Sabelle Hjeij,Franck Ménétrier,Isabelle Chauvel,Stéphane Fraichard,Quentin Bonninet al. The International Symposium on Olfaction and Taste (ISOT), Jun 2024, Reykjavík, Iceland Poster de conférence hal-04771537v1
Impact of aldehyde dehydrogenases and aldo-keto reductases on human olfactory peri-receptor events Valentin Boichot,Franck Ménétrier,Jean-Michel Saliou,Frédéric Lirussi,Francis Canonet al. 45. annual meeting - association for chemoreception sciences (AChemS), Apr 2023, Bonita Springs, Florida, United States. Poster de conférence hal-04095217v1
[Thu-P1-027] Pheromone-induced odour learning and outstanding detection abilities in the newborn rabbit Marie-Sabelle Hjeij,G. Coureaud,Samuel Garcia,Marc Thévenet,Jean-Marie Heydelet al. 32. international congress of the european-chemoreception-research-organization (ECRO), Aug 2022, Berlin, Germany Poster de conférence hal-03810680v1
The NAOMI (Nasal Odorant Metabolites) consortium: an international, multidisciplinary consortium investigating how metabolites resulting from nasal enzymatic odorant metabolism can shape odor perception Jean-Marie Heydel,Thierry Thomas-Danguin,Jean-Luc Le Quéré,F. Neiers,Andrea Buettneret al. 16. Weurman Flavour Research Symposium, May 2021, Dijon, France. Poster de conférence hal-03253429v1
Characterization of rat glutathione transferases in olfactory mucus and epithelium Jean-Marie Heydel,Franck Ménétrier,Christine Belloir,Philippe Faure,Evelyne Chavanneet al. 29. Annual Meeting of the European-Chemoreception-Research-Organization, Sep 2019, Trieste, Italy. pp.P24, ECRO 2019 Poster de conférence hal-02885473v1
Odorant metabolism in olfactory mucus: characterization and impact on olfactory perception Philippe Faure,Aline Robert-Hazotte,Fabrice Neiers,Franck Menetrier,Gérard Coureaudet al. 40. annual meeting - association for chemoreception sciences (AChemS), Apr 2018, Bonita Springs, Florida, United States. Oxford University Press, Chemical Senses, 43 (7), 1 p., 2018 Poster de conférence hal-02735550v1
Odorants' metabolism in Human: a critical role in odor perception revealed Aline Robert Hazotte,Thierry Thomas-Danguin,Théoline Fèvre,Catherine Potin,Jean-Marie Heydelet al. 40. annual meeting - association for chemoreception sciences (AChemS), Apr 2018, Bonita Springs, Florida, United States. , Chemical Senses, 43 (7), 1 p., 2018 Poster de conférence hal-02736238v1
Structural and enzymatic characterization of a Drosophila melanogaster glutathione transferase overexpressed in the sensory organs after exposure to bitter molecules in food Daniel Gonzalez,Stéphane Fraichard,Jean-François Ferveur,Yves Artur,Loïc Briandet al. 17. international symposium on Olfaction and taste (ISOT), Jun 2016, Yokohama, Japan. Oxford University Press, Chemical Senses, 41 (9), 1 p., 2016, Chemical Senses Poster de conférence hal-01579982v1
P45 - Drosophila melanogaster glutathione transferase overexpressed in the sensory organs after exposure to bitter molecules in food Daniel Gonzalez,Stéphane Fraichard,Jean-François Ferveur,Yves Artur,Loïc Briandet al. The 26th Annual Meeting of the European-Chemoreception-Research-Organization (ECRO), Sep 2016, Dijon, France Poster de conférence hal-02917669v1
Inhibition of the mammary pheromone catabolism by a second odorant present in the same mixture Jean-Marie Heydel,Hassan-Ismail Hanser,Philippe Faure,Arièle Legendre,Benoist Schaalet al. 24. Annual Meeting of the European-Chemoreception-Research-Organization (ECRO), Sep 2014, Dijon, France. Oxford University Press, Chemical Senses, 40 (3), pp.2, 2015, Proceedings of the 24. Annual Meeting of the European-Chemoreception-Research-Organization (ECRO) Poster de conférence hal-02743312v1
Odorant biotransformation by human gluthatione-S-transferases Quentin Dubant,Evelyne Chavanne,Christine Belloir,Jean-Marie Heydel,Yves Arturet al. 24. Annual Meeting of the European Chemoreception Research Organization (ECRO 2014), Sep 2014, Dijon, France. Oxford University Press, Chemical Senses, 40 (3), pp.2, 2015, Abstracts from the 24th Annual Meeting of the European Chemoreception Research Organization (ECRO 2014). ⟨10.1093/chemse/bju073⟩ Poster de conférence hal-02744377v1
Olfactory xenobiotic metabolizing enzymes have an impact on the stimulating properties of some odorants Nicolas Thiebaud,Stéphanie Veloso da Silva,Ingrid Jakob,Gilles Gs Sicard,Yves Arturet al. 32. Annual meeting (AChemS), Apr 2010, Saint Petersburg, Florida, United States. 1 p., 2010 Poster de conférence hal-02818714v1
Rôle des enzymes du métabolisme des xénobiotiques dans la perception de la caféine chez la drosophile Alexandra Coelho,Stéphane Fraichard,Philippe Faure,Jean-Marie Heydel 16. Colloque de Biologie de l’Insecte, Oct 2010, Lyon, France. 1 p., 2010 Poster de conférence hal-02822422v1
Major sulfation pathway for resveratrol metabolism in human hepatic derived cells and resveratrol –dependent inducibility of conjugating enzymes. Perspective in nutritional prevention Allan Lançon,Nathalie Hanet,Brigitte Jannin,Dominique Delmas,Jean-Marie Heydelet al. European Partnership Meetings: Taste, Nutrition, Health, Jun 2007, Dijon, France Poster de conférence hal-03838370v1
Endocrine disruptors found in food modulate estradiol cellular metabolism Nathalie Hanet,Allan Lançon,Jean-Marie Heydel,Dominique Delmas,Brigitte Janninet al. 2. congrès international Santé et Nutrition VITAGORA, Mar 2007, Dijon, France Poster de conférence hal-03757959v1
Major sulfation pathway for resveratrol metabolism in human hepatic derived cells and resveratrol –dependent inducibility of conjugating enzymes. Perspective in nutritional prevention Allan Lançon,Nathalie Hanet,Brigitte Jannin,Dominique Delmas,Jean-Marie Heydelet al. 2. congrès international Santé et Nutrition VITAGORA, Mar 2007, Dijon, France Poster de conférence hal-03838598v1

Chapitre d'ouvrage (6)

Odorant metabolizing enzymes in the peripheral olfactory process Fabrice Neiers,Jeanne Mérignac-Lacombe,Jean-Marie Heydel Elisabeth Guichard; Christian Salles. Flavor: From Food to Behaviors, Wellbeing and Health, Second edition, Chapter 5, , pp.127-147, 2023, 978-0-323-89903-1. ⟨10.1016/B978-0-323-89903-1.00014-1⟩ Chapitre d'ouvrage hal-04002413v1
Odorant metabolizing enzymes in the peripheral olfactory process Jean-Marie Heydel,Hassan-Ismail Hanser,Philippe Faure,Fabrice Neiers Flavour: From food to perception, John Wiley & Sons, Inc., 424 p., 2017, 978-1-118-92941-4 Chapitre d'ouvrage hal-01585726v1
Système olfacto-gustatif et toxicologie Anne-Marie Le Bon,Jean-Marie Heydel,Fabrice Cheruel Odorat et goût. De la neurobiologie des sens chimiques aux applications, Editions Quae, 2012, Synthèses (Quae), ISBN-13 : 978-2-7592-1770-0 Chapitre d'ouvrage hal-02804272v1
Système olfacto-gustatif et toxicologie Anne-Marie Le Bon,Jean-Marie Heydel,Fabrice Cheruel Salesse, Roland ; Gervais, Rémi. Odorat et goût. De la neurobiologie des sens chimiques aux applications, Editions Quae, pp.465-472, 2012, Collection Synthèses, 978-2-7592-1770-0 Chapitre d'ouvrage hal-00787914v1
Périréception et protéines porteuses Martine Maïbèche,Jean-Marie Heydel,Anne-Marie Le Bon,Jérôme Golebiowski,Loïc Briand Salesse, Roland ; Gervais, Rémi. Odorat et goût. De la neurobiologie des sens chimiques aux applications, Editions Quae, pp.61-73, 2012, Collection Synthèses, 978-2-7592-1770-0 Chapitre d'ouvrage hal-00787942v1
Périréception et protéines porteuses Martine M. Maibeche Coisne,Jean-Marie Heydel,Anne-Marie Le Bon,Jérôme Golebiowski,Loïc Briand Odorat et goût. De la neurobiologie des sens chimiques aux applications, Editions Quae, 2012, Synthèses (Quae), 978-2-7592-1770-0 978-2-7592-1770-0 Chapitre d'ouvrage hal-02809036v1

Proceedings/Recueil des communications (2)

Is there a role for salivary detoxification enzymes in taste perception? Mathieu Schwartz,Hélène Brignot,Evelyne Chavanne,Gilles Feron,Thomas Hummelet al. 2021, Proceedings of the 16. Weurman flavour research symposium, ⟨10.5281/zenodo.5575005⟩ Proceedings/Recueil des communications hal-03686461v1
Characterization of rat glutathione transferases in olfactory mucus and epithelium Jean-Marie Heydel,Franck Ménétrier,Christine Belloir,Philippe Faure,Evelyne Chavanne /, Chemical Senses, 45 (2), Oxford University Press, pp.150-150, 2020 Proceedings/Recueil des communications hal-02943942v1

Autre publication scientifique (1)

Odorant metabolism in olfactory mucus: characterization and impact on olfactory perception. Philippe Faure,Aline Robert Hazotte,Fabrice Neiers,Franck Menetrier,Gérard Coureaudet al. 2018 Autre publication scientifique hal-02386821v1

Article de blog scientifique (1)

ARET : colloque 2018 au CSGA Dijon. 28 et 29 mai 2018 - CSGA, 9E boulevard Jeanne d'Arc, Dijon Roland Salesse,Loïc Briand,Benoist Schaal,Laurence Mulon,Anne-Claire Offeret al. 2018 Article de blog scientifique hal-02785817v1