Jean Michel PEYRIN Directeur de Recherche CNRS

Publications

Article dans une revue (34)

Immune cell infiltration of patient derived glioblastoma cell spheroids in acoustic levitation in bulk acoustic wave devices Xavier Mousset,Shuake Kuermanbayi,Chloé Dupuis,Nathan Jeger-Madiot,Virgile Delaunayet al. Lab on a Chip, 2025, ⟨10.1039/d5lc00249d⟩ Article dans une revue hal-05350906v1
Influence of microgravity on spontaneous calcium activity of primary hippocampal neurons grown in microfluidic chips Pierre-Ewen Lecoq,Chloé Dupuis,Xavier Mousset,Xavier Benoit-Gonnin,Jean-Michel Peyrinet al. NPJ Microgravity, 2024, 10 (1), pp.15. ⟨10.1038/s41526-024-00355-x⟩ Article dans une revue hal-04455636v1
Assessment of corneal nerve regeneration after axotomy in a compartmentalized microfluidic chip model with automated 3D high resolution live-imaging Noémie Bonneau,Anaïs Potey,Frédéric Blond,Camille Guerin,Christophe Baudouinet al. Frontiers in Cellular Neuroscience, 2024, 18, pp.1417653. ⟨10.3389/fncel.2024.1417653⟩ Article dans une revue hal-04728861v1
Influence of Microgravity on Spontaneous Calcium Activity of Primary Hippocampal Neurons. Pierre-Ewen Lecoq,Chloé Dupuis,Xavier Mousset,Xavier Benoit-Gonnin,Jean-Michel Peyrinet al. NPJ Microgravity, In press, ⟨10.21203/rs.3.rs-3220173/v1⟩ Article dans une revue hal-04303048v1
Synapses do not facilitate prion-like transfer of alpha-synuclein: a quantitative study in reconstructed unidirectional neural networks Josquin Courte,Ngoc Anh Le,Teng Pan,Luc Bousset,Ronald Melkiet al. Cellular and Molecular Life Sciences, 2023, 80 (10), pp.284. ⟨10.1007/s00018-023-04915-4⟩ Article dans une revue hal-04205202v1
Glioblastoma cell motility depends on enhanced oxidative stress coupled with mobilization of a sulfurtransferase Mirca S Saurty-Seerunghen,Thomas Daubon,Léa Bellenger,Virgile Delaunay,Gloria Castroet al. Cell Death and Disease, 2022, 13 (10), pp.913. ⟨10.1038/s41419-022-05358-8⟩ Article dans une revue hal-03836497v1
Controlling the force and the position of acoustic traps with a tunable acoustofluidic chip: Application to spheroid manipulations Nathan Jeger-Madiot,Xavier Mousset,Chloé Dupuis,Lucile Rabiet,Mauricio Hoyoset al. Journal of the Acoustical Society of America, 2022, 151 (6), pp.4165-4179. ⟨10.1121/10.0011464⟩ Article dans une revue hal-03832185v2
HSPA9/Mortalin mediates axo-protection and modulates mitochondrial dynamics in neurons Cécile Ferré,Anne Thouard,Alexandre Bétourné,Anne-Louise Le Dorze,Pascale Belengueret al. Scientific Reports, 2021, 11 (1), pp.17705. ⟨10.1038/s41598-021-97162-1⟩ Article dans une revue hal-03365325v1
The expression level of alpha-synuclein in different neuronal populations is the primary determinant of its prion-like seeding Josquin Courte,Luc Bousset,Ysander von Boxberg,Catherine Villard,Ronald Melkiet al. Scientific Reports, 2020, 10, pp.4895. ⟨10.1038/s41598-020-61757-x⟩ Article dans une revue cea-02511811v1
Propagation of α-Synuclein Strains within Human Reconstructed Neuronal Network Simona Gribaudo,Philippe Tixador,Luc Bousset,Alexis Fenyi,Patricia Linoet al. Stem Cell Reports, 2019, 12 (2), pp.230-244. ⟨10.1016/j.stemcr.2018.12.007⟩ Article dans une revue hal-02050472v1
Glutamatergic and dopaminergic modulation of cortico-striatal circuits probed by dynamic calcium imaging of networks reconstructed in microfluidic chips Benjamin Lassus,Jérémie Naudé,Philippe Faure,Denis Guedin,Ysander von Boxberget al. Scientific Reports, 2018, 8, pp.17461. ⟨10.1038/s41598-018-35802-9⟩ Article dans une revue hal-01943765v1
Dysregulated Neurotransmission induces Trans-synaptic degeneration in reconstructed Neuronal Networks Bérangère Deleglise,Benjamin Lassus,Vanessa Soubeyre,Mohamed Doulazmi,Bernard Brugget al. Scientific Reports, 2018, 8, pp.11596. ⟨10.1038/s41598-018-29918-1⟩ Article dans une revue hal-01907549v1
Cellular mechanisms responsible for cell-to-cell spreading of prions Didier Vilette,Josquin Courte,Jean Michel Peyrin,Laurent Coudert,Laurent Schaefferet al. Cellular and Molecular Life Sciences, 2018, 75 (14), pp.2557-2574. ⟨10.1007/s00018-018-2823-y⟩ Article dans une revue (data paper) hal-04299046v1
Reconstruction of directed neuronal networks in a microfluidic device with asymmetric microchannels Josquin Courte,Renaud Renault,Audric Jan,Jean-Louis Viovy,Jean-Michel Peyrinet al. Methods in Cell Biology, 2018, Microfluidics in Cell Biology Part C: Microfluidics for Cellular and Subcellular Analysis, 148, pp.71-95. ⟨10.1016/bs.mcb.2018.07.002⟩ Article dans une revue hal-02369984v1
Cellular mechanisms responsible for cell-to-cell spreading of prions Didier Vilette,Josquin Courte,Jean Michel Peyrin,Laurent Coudert,Laurent Schaefferet al. Cellular and Molecular Life Sciences, 2018, 75 (14), pp.2557-2574. ⟨10.1007/s00018-018-2823-y⟩ Article dans une revue hal-02328248v1
Correction to: Cellular mechanisms responsible for cell-to-cell spreading of prions. Didier Vilette,Josquin Courte,Jean Michel Peyrin,Laurent Coudert,Laurent Schaefferet al. Cellular and Molecular Life Sciences, 2018, 75 (14), pp.2575. ⟨10.1007/s00018-018-2853-5⟩ Article dans une revue hal-02617769v1
Manipulation of the N-terminal sequence of the Borna disease virus X protein improves its mitochondrial targeting and neuroprotective potential Cecile A. Ferre,Noelie Davezac,Anne Thouard,Jean-Michel Peyrin,Pascale Belengueret al. FASEB Journal, 2016, 30 (4), pp.1523-1533. ⟨10.1096/fj.15-279620⟩ Article dans une revue hal-01542857v1
In-mold patterning and actionable axo-somatic compartmentalization for on-chip neuron culture Ayako Yamada,Maéva Vignes,Cécile Bureau,Alexandre Mamane,Bastien Venzacet al. Lab on a Chip, 2016, 16 (11), pp.2059-2068. ⟨10.1039/C6LC00414H⟩ Article dans une revue hal-01324932v1
Alterations of mitochondrial dynamics allow retrograde propagation of locally initiated axonal insults Benjamin Lassus,Sebastien Magifico,Sandra Pignon,Pascale Belenguer,Marie-Christine Miquelet al. Scientific Reports, 2016, 6, pp. 32777 ⟨10.1038/srep32777⟩ Article dans une revue hal-01362371v1
Combining Microfluidics, Optogenetics and Calcium Imaging to Study Neuronal Communication In Vitro Renaud Renault,Nirit Sukenik,Stéphanie Descroix,Laurent Malaquin,Jean-Louis Viovyet al. PLoS ONE, 2015, 10 (4), pp.e0120680. ⟨10.1371/journal.pone.0120680⟩ Article dans une revue hal-01227804v1
Double-Edge Sword of Sustained ROCK Activation in Prion Diseases through Neuritogenesis Defects and Prion Accumulation Aurélie Alleaume-Butaux,Simon Nicot,Mathéa Pietri,Anne Baudry,Caroline Dakowskiet al. PLoS Pathogens, 2015, 11 (8), pp.e1005073. ⟨10.1371/journal.ppat.1005073⟩ Article dans une revue hal-01223830v1
Combination of memantine and vitamin D prevents axon degeneration induced by amyloid-beta and glutamate Cédric Annweiler,Bernard Brugg,Jean-Michel Peyrin,Robert Bartha,Olivier Beauchet Neurobiology of Aging, 2014, 35 (2), pp.331-335. ⟨10.1016/j.neurobiolaging.2013.07.029⟩ Article dans une revue istex hal-01544168v1
β-amyloid induces a dying-back process and remote trans-synaptic alterations in a microfluidic-based reconstructed neuronal network Bérangère Deleglise,Sébastien Magnifico,Eric Duplus,Pauline Vaur,Vanessa Soubeyreet al. Acta Neuropathologica Communications, 2014, 2, pp.145. ⟨10.1186/s40478-014-0145-3⟩ Article dans une revue hal-01221362v1
A viral peptide that targets mitochondria protects against neuronal degeneration in models of Parkinson's disease Marion Szelechowski,Alexandre Betourne,Yann Monnet,Cecile A. Ferre,Anne Thouardet al. Nature Communications, 2014, 5, pp.5181. ⟨10.1038/ncomms6181⟩ Article dans une revue hal-01542865v1
NAD(+) acts on mitochondrial SirT3 to prevent axonal caspase activation and axonal degeneration Sebastien Magnifico,Laure Saias,Berangere Deleglise,Eric Duplus,Devrim Kilincet al. FASEB Journal, 2013, 27 (12), pp.4712-4722. ⟨10.1096/fj.13-229781⟩ Article dans une revue hal-01542868v1
Synapto-protective drugs evaluation in reconstructed neuronal network Bérangère Deleglise,Benjamin Lassus,Vanessa Soubeyre,Aurélie Alleaume-Butaux,Johannes J. Hjorthet al. PLoS ONE, 2013, 8 (8), pp.1-9. ⟨10.1371/journal.pone.0071103⟩ Article dans une revue hal-01221378v1
PDK1 decreases TACE-mediated α-secretase activity and promotes disease progression in prion and Alzheimer's diseases Mathéa Pietri,Caroline Dakowski,Samia Hannaoui,Aurélie Alleaume-Butaux,Julia Hernandez-Rappet al. Nature Medicine, 2013, 19 (9), pp.1124-1131. ⟨10.1038/nm.3302⟩ Article dans une revue hal-02363130v1
Microfluidic construction of minimalistic neuronal co-cultures Ngoc-Duy Dinh,Ya-Yu Chiang,Heike Hardelauf,Jenny Baumann,Emily Jacksonet al. Lab on a Chip, 2013, 13 (7), pp.1402-1412. ⟨10.1039/c3lc41224e⟩ Article dans une revue hal-01542866v1
Endogenous prion protein conversion is required for prion-induced neuritic alterations and neuronal death Sabrina Cronier,Julie Carimalo,Brigitte Schaeffer,Emilie Jaumain,Vincent Béringueet al. FASEB Journal, 2012, 26 (9), pp.3854-3861. ⟨10.1096/fj.11-201772⟩ Article dans une revue hal-01542871v1
Axon diodes for the reconstruction of oriented neuronal networks in microfluidic chambers Jean-Michel Peyrin,Bérangère Deleglise,Laure Saias,Maeva Vignes,Paul Gougiset al. Lab on a Chip, 2011, 11 (21), pp.3663. ⟨10.1039/c1lc20014c⟩ Article dans une revue hal-02372610v1
Wallerian-Like Degeneration of Central Neurons After Synchronized and Geometrically Registered Mass Axotomy in a Three-Compartmental Microfluidic Chip Devrim Kilinc,Jean-Michel Peyrin,Vanessa Soubeyre,Sébastien Magnifico,Laure Saiaset al. Neurotoxicity Research, 2011, 19 (1), pp.149-161. ⟨10.1007/s12640-010-9152-8⟩ Article dans une revue hal-03952503v1
Controlled proteolysis of normal and pathological prion protein in a microfluidic chip. Anne Le Nel,Nicolas Minc,Claire Smadja,Marcela Slovakova,Zuzana Bilkovaet al. Lab on a Chip, 2008, 8 (2), pp.294-301. ⟨10.1039/b715238h⟩ Article dans une revue istex hal-00258875v1
Prion strain- and species-dependent effects of antiprion molecules in primary neuronal cultures Sabrina Cronier,Vincent Béringue,Anne Bellon,Jean-Michel Peyrin,Hubert H. Laude Journal of Virology, 2007, 81 (24), pp.13794-13800 . ⟨10.1128/JVI.01502-07⟩ Article dans une revue hal-02666304v1
Prions can infect primary cultured neurons and astrocytes and promote neuronal cell death Sabrina Cronier,Hubert H. Laude,Jean-Michel Peyrin Proceedings of the National Academy of Sciences of the United States of America, 2004, 101 (33), pp.12271-12276. ⟨10.1073/pnas.0402725101⟩ Article dans une revue hal-02682732v1

Communication dans un congrès (10)

Towards concentric topology in organoids: Structuration and culture of brain derived spheroids in a Bulk Acoustic Wave resonator Chloé Dupuis,Xavier Mousset,Guillaume Viraye,Pierre-Ewen Lecoq,Mauricio Hoyoset al. 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2022), Oct 2022, Hangzhou, China Communication dans un congrès hal-03865434v1
Study of the influence of microgravity on brain derived spheroids in acoustic levitation Pierre-Ewen Lecoq,Chloé Dupuis,Xavier Mousset,Xavier Benoit-Gonin,Mauricio Hoyoset al. 27th European Low Gravity Research Association Biennial Symposium, Sep 2022, Lisbonne, Portugal Communication dans un congrès hal-03865465v1
Characterization and control of a broadband acoustic cavity: Application to cells spheroids manipulation Nathan Jeger-Madiot,Xavier Mousset,Chloé Dupuis,Lucile Rabiet,Mauricio Hoyoset al. Acoustofluidics 2022, Oct 2022, Glasgow, United Kingdom Communication dans un congrès hal-03864003v1
Novel acoustofluidic approach using a Bulk Acoustic Wave resonator to control the topology and culture conditions of brain derived spheroids Chloé Dupuis,Xavier Mousset,Guillaume Viraye,Pierre-Ewen Lecoq,Mauricio Hoyoset al. Acoustofluidics 2022, Oct 2022, Glasgow, United Kingdom Communication dans un congrès hal-03864057v1
Prion replication sensitizes neurons to proinflammatory cytokines Benoît Schneider,Damien Loubet,Elodie Pradines,Yannick Bailly,Jean-Michel Peyrinet al. Prion 2009, Sep 2009, Chalkidiki, Greece Communication dans un congrès hal-02754312v1
Etude de l'endoprotéolyse de la PrPSc dans différents systèmes cellulaires permissifs au prion Mohammed M. Moudjou,Michel Dron,Jerome Chapuis,Julie Bernard,Muhammad Khalid Salamatet al. Journées d'Animation Scientifique du Département Santé Animale, May 2009, Port d'Albret, France Communication dans un congrès hal-02754794v1
Endogenous PrP conversion is required for prion-induced neuritic alterations and neuronal death Sabrina Cronier,Julie Carimalo,Brigitte Schaeffer,Marie-Christine Miquel,Hubert H. Laudeet al. Prion 2009, Sep 2009, Chalkidiki, Greece Communication dans un congrès hal-02753346v1
Endogenous N-terminal trimming of PrPSc occurs at a fairly variable level depending on the infected host cell Mohammed M. Moudjou,Michel Dron,Jerome Chapuis,Julie Bernard,Muhammad Khalid Salamatet al. Prion 2008, Oct 2008, Madrid, Spain Communication dans un congrès hal-02751313v1
Evaluation of anti-prion drug potency in primary nerve cell cultures infected by prions from various species Sabrina Cronier,Vincent Béringue,A. Bellon,M. Fontes,Jean-Luc Vilotteet al. Prion 2006, Oct 2006, Turin, Italy Communication dans un congrès hal-02755671v1
Prion replication in primary cultures of brain-derived neuronal cells Sabrina Cronier,Jean-Michel Peyrin,Hubert H. Laude 2. International Symposium on the New Prion Biology, May 2005, Venice, Italy. n.p Communication dans un congrès hal-02833223v1

Poster de conférence (2)

In vitro microfluidic design to study mitochondria-microtubules interactions after an axonaltraumatic injury Theo Andriot,Chloé Dupuis,Teng Pan,Jean-Michel Peyrin,Fatiha Nothiaset al. FENS, Jul 2022, Paris, France Poster de conférence hal-03946575v1
In vitro experimental design to study axonal behavior after a traumatic injury Théo Andriot,Chloé Dupuis,Josquin Courte,Teng Pan,Jean-Michel Peyrinet al. Neuro France 2021, May 2021, Paris, France Poster de conférence hal-03947638v1

Chapitre d'ouvrage (2)

Propagation of Distinct α-Synuclein Strains Within Human Reconstructed Neuronal Network and Associated Neuronal Dysfunctions Simona Gribaudo,Luc Bousset,Josquin Courte,Ronald Melki,Jean-Michel Peyrinet al. Protein Aggregation, 2551 (10), Springer US, pp.357-378, 2023, Methods in Molecular Biology, ⟨10.1007/978-1-0716-2597-2_24⟩ Chapitre d'ouvrage hal-03836488v1
Subcellular Compartmentalization for Neurobiology: Focusing on the Axon Agata Blasiak,Devrim Kilinc,Jean-Michel Peyrin Handbook of Neuroengineering, Springer Singapore, pp.1-35, 2021, ⟨10.1007/978-981-15-2848-4_1-1⟩ Chapitre d'ouvrage hal-03836516v1

Pré-publication, Document de travail (2)

Immune Cells Infiltration of Patient Derived Glioblastoma Cells spheroids in Acoustic Levitation in Bulk Acoustic Wave devices Mousset Xavier,Kuermanbayi Shuake,Chloé Dupuis,Jeger-Madiot Nathan,Delaunay Virgileet al. 2025 Pré-publication, Document de travail hal-05343597v1
Influence of gravity variations on the activity of neuronal spheroids in an acoustic trap Pierre-Ewen Lecoq,Guillaume Viraye,Chloe Dupuis,Xavier Benoit-Gonin,Jean-Luc Aideret al. 2025 Pré-publication, Document de travail hal-04638248v2