Jérôme Henri

Publications

Article dans une revue (27)

Semi-mechanistic PK/PD modelling of enrofloxacin against sensitive Pasteurella multocida : inter-strain variability and prediction of efficacy in pigs Alexis Viel,Anthony Khaled,Mathias Devreese,Mireille Bruneau,Jérôme Henri Journal of Applied Microbiology, 2026, ⟨10.1093/jambio/lxag045⟩ Article dans une revue hal-05510220v1
In vitro hepatic metabolism and associated binding of enniatin B Ludovic Le Hégarat,Estelle Dubreil,Nicolas Le Yondre,Solenne Martin,Françoise Bréeet al. Toxicology, 2026, 521, pp.154379. ⟨10.1016/j.tox.2025.154379⟩ Article dans une revue hal-05453769v1
Population pharmacokinetic modeling of sulfadimethoxine, sulfadiazine and sulfamethoxazole combined to trimethoprim in pigs Marine Boulanger,Jean-François Taillandier,Jérôme Henri,Mathias Devreese,Siegrid de Baereet al. Veterinary Quarterly, 2025, 45 (1), pp.2565351. ⟨10.1080/01652176.2025.2565351⟩ Article dans une revue hal-05290011v1
Combining fugacity and physiologically based toxicokinetic concepts in a mechanistic model describing the fate of lipophilic contaminants in lactating cows Sylvain Lerch,Olivier Martin,Agnés Fournier,Isabelle Ortigues-Marty,Jérôme Henri Environment International, 2025, 199, pp.109509. ⟨10.1016/j.envint.2025.109509⟩ Article dans une revue hal-05064148v1
Hazard characterization of Alternaria toxins to identify data gaps and improve risk assessment for human health Henriqueta Louro,Ariane Vettorazzi,Adela López de Cerain,Anastasia Spyropoulou,Anita Solhauget al. Archives of Toxicology, 2024, 98 (2), pp.425-469. ⟨10.1007/s00204-023-03636-8⟩ Article dans une revue anses-04383220v1
Statement on the toxicological properties and maximum residue levels of acetamiprid and its metabolites Antonio Hernandez‐jerez,Tamara Coja,Martin Paparella,Anna Price,Jerome Henriet al. EFSA Journal, 2024, 22, pp.1-84. ⟨10.2903/j.efsa.2024.8759⟩ Article dans une revue anses-04700110v1
Pharmacokinetic modeling of sulfamethoxazole-trimethoprim and sulfadiazine-trimethoprim combinations in broilers Marine Boulanger,Jean-François Taillandier,Jérôme Henri,Mathias Devreese,Siegrid de Baereet al. Poultry Science, 2024, 103 (11), pp.104200. ⟨10.1016/j.psj.2024.104200⟩ Article dans une revue anses-04687626v1
PBPK Model To Predict Marbofloxacin Distribution in Edible Tissues and Intestinal Exposure in Pigs Alexis Viel,Anis Nouichi,Mélanie Le van Suu,Jean-Guy Rolland,Pascal Sanderset al. Journal of Agricultural and Food Chemistry, 2023, 71 (10), pp.4358-4370. ⟨10.1021/acs.jafc.2c06561⟩ Article dans une revue anses-04167240v1
Determination of the elimination half-life of Glyphosate and its main metabolite, AMPA, in chicken plasma Mathias Fréville,Jérôme Henri,Anthony Estienne,Loïse Serra,Christelle Raméet al. Toxicology Letters, 2023, 389, pp.19 - 25. ⟨10.1016/j.toxlet.2023.10.009⟩ Article dans une revue anses-04265997v1
Ionophore coccidiostats – disposition kinetics in laying hens and residues transfer to eggs Abubakar Bello,Jérôme Henri,Alexis Viel,Jonathan Paul Mochel,Błażej Poźniak Poultry Science, 2023, 102 (1), pp.102280. ⟨10.1016/j.psj.2022.102280⟩ Article dans une revue anses-03922139v1
Permeability of the Cyanotoxin Microcystin-RR across a Caco-2 Cells Monolayer Jérôme Henri,Rachelle Lanceleur,Jean-Michel Delmas,Valérie Fessard,Antoine Huguet Toxins, 2021, 13 (3), pp.178. ⟨10.3390/toxins13030178⟩ Article dans une revue anses-03266193v1
A PBPK model to study the transfer of α- hexabromocyclododecane (α-HBCDD) to tissues of fast-and slow-growing broilers Bertrand Méda,Angélique Travel,Yann Guyot,Jérôme Henri,Eric Royeret al. Food additives & contaminants. Part A. Chemistry, analysis, control, exposure & risk assessment, 2020, 37 (2), pp.316-331. ⟨10.1080/19440049.2019.1681596⟩ Article dans une revue anses-02359869v1
A Population WB-PBPK Model of Colistin and its Prodrug CMS in Pigs: Focus on the Renal Distribution and Excretion Alexis Viel,Jérôme Henri,Salim Bouchène,Julian Laroche,Jean-Guy Rollandet al. Pharmaceutical Research, 2018, 35, pp.92. ⟨10.1007/s11095-018-2379-4⟩ Article dans une revue anses-01743743v1
The present and future of withdrawal period calculations for milk in the European Union: Focus on heterogeneous, nonmonotonic data Anne Chevance,Anne-Marie Jacques,Michel Laurentie,Pascal Sanders,Jérôme Henri Journal of Veterinary Pharmacology and Therapeutics, 2017, 40 (3), pp.218-230. ⟨10.1111/jvp.12351⟩ Article dans une revue anses-01419605v1
Lack of experimental evidence to support mcr-1- positive escherichia coli strain selection during oral administration of colistin at recommended and higher dose given by gavage in weaned piglets Alexis Viel,Jérôme Henri,Agnès Perrin-Guyomard,Julian Laroche,William Couetet al. International Journal of Antimicrobial Agents, 2017, 51 (1), pp.128-131. ⟨10.1016/j.ijantimicag.2017.04.013⟩ Article dans une revue anses-01570163v1
The present and future of withdrawal period calculations for milk in the European Union: Dealing with data below the limit of quantification Jérôme Henri,Anne-Marie Jacques,Pascal Sanders,Anne Chevance,Michel Laurentie Journal of Veterinary Pharmacology and Therapeutics, 2017, 40 (2), pp.116-122. ⟨10.1111/jvp.12343⟩ Article dans une revue anses-01421392v1
A physiologically based pharmacokinetic model for chickens exposed to feed supplemented with monensin during their lifetime Jérôme Henri,Romain Carrez,Bertrand Méda,Michel Laurentie,Pascal Sanders Journal of Veterinary Pharmacology and Therapeutics, 2016, 40 (4), pp.1-13. ⟨10.1111/jvp.12370⟩ Article dans une revue anses-01418236v1
Tools to evaluate pharmacokinetics data for establishing maximum residue limits for approved veterinary drugs: examples from JECFA's work Pascal Sanders,Jérôme Henri,Michel Laurentie Drug Testing and Analysis, 2016, 8 (5-6), pp.565-571. ⟨10.1002/dta.2006⟩ Article dans une revue anses-01348712v1
Low in vitro permeability of the cyanotoxin microcystin-LR across a Caco-2 monolayer: With identification of the limiting factors using modelling Jérôme Henri,Antoine Huguet,Jean-Michel Delmas,Aurore Besson,Pascal Sanderset al. Toxicon, 2014, pp.1-11. ⟨10.1016/j.toxicon.2014.07.023⟩ Article dans une revue istex hal-01076975v1
Low or high doses of cefquinome targeting low or high bacterial inocula cure Klebsiella pneumoniae lung infections but differentially impact the levels of antibiotic resistance in fecal flora. Maleck V. Vasseur,Michel Laurentie,Jean-Guy Rolland,Agnès Perrin-Guyomard,Jérôme Henriet al. Antimicrobial Agents and Chemotherapy, 2014, 58 (3), pp.1744-8. ⟨10.1128/AAC.02135-13⟩ Article dans une revue hal-00978511v1
Permeability of dihydro- and cysteine-brevetoxin metabolites across a Caco-2 cell monolayer Jérôme Henri,Ta Leighfield,Rachelle Lanceleur,Antoine Huguet,Js Ramsdellet al. Harmful Algae, 2014, 32, pp.22-26. ⟨10.1016/j.hal.2013.11.007⟩ Article dans une revue istex hal-00998117v1
Comparative Cytotoxicity, Oxidative Stress, and Cytokine Secretion Induced by Two Cyanotoxin Variants, Microcystin LR and RR, in Human Intestinal Caco-2 Cells. Antoine Huguet,Jérôme Henri,Mélanie Petitpas,Kevin Hogeveen,Valérie Fessard Journal of Biochemical and Molecular Toxicology, 2013, 27 (5), pp.253-258. ⟨10.1002/jbt.21482⟩ Article dans une revue istex hal-00815224v1
Comparison of the oral bioavailability and tissue disposition of monensin and salinomycin in chickens and turkeys. Jérôme Henri,R. Maurice,G. Postollec,Estelle Dubreil-Cheneau,Brigitte Roudautet al. Journal of Veterinary Pharmacology and Therapeutics, 2011, epub ahead of print. ⟨10.1111/j.1365-2885.2011.01285.x⟩ Article dans une revue istex hal-00601106v1
Implementation and assessment of the quality management system in research in a laboratory of the French Food Safety Agency: Application to PhD student work Jérôme Henri,Pascal Sanders,Hélène Lelièvre,Nathalie Cadieu Accreditation and Quality Assurance, 2009, 14 (4), pp.207-217. ⟨10.1007/s00769-009-0505-z⟩ Article dans une revue hal-00405458v1
Bioavailability, distribution and depletion of monensin in chickens Jérôme Henri,Christine Burel,P. Sanders,M. Laurentie Journal of Veterinary Pharmacology and Therapeutics, 2009, 32 (5), pp.451-456. ⟨10.1111/j.1365-2885.2009.01063.x⟩ Article dans une revue istex hal-01985346v1
Cytochrome P450‐dependent metabolism of monensin in hepatic microsomes from chickens and turkeys Jérôme Henri,J. Manceau,P. Sanders,M. Laurentie Journal of Veterinary Pharmacology and Therapeutics, 2008, 31 (6), pp.584-586. ⟨10.1111/j.1365-2885.2008.00996.x⟩ Article dans une revue istex hal-05468571v1
Liquid chromatography–electrospray tandem mass spectrometric method for quantification of monensin in plasma and edible tissues of chicken used in pharmacokinetic studies: Applying a total error approach Estelle Chéneau,Jérôme Henri,Yvette Pirotais,Jean-Pierre Abjean,Brigitte Roudautet al. Journal of Chromatography B - Analytical Technologies in the Biomedical and Life Sciences, 2007, 850 (1-2), pp.15-23. ⟨10.1016/j.jchromb.2006.10.072⟩ Article dans une revue istex hal-05468562v1

Poster de conférence (17)

Interspecies and cell models comparison of enniatin b1 in vitro hepatic clearance Mariam Mahdjoub,Charlène Gendre,Estelle Dubreil-Chéneau,Ludovic Le Hegarat,Jérôme Henri 37th Group of Metabolism and Pharmacokinetics (GMP 2025) : Pioneering Advances in Pharmacokinetics, Oct 2025, Gentilly, France Poster de conférence hal-05477628v1
Use of New Approach Methodologies (NAMs) in unravelling interspecies Toxicokinetics of Enniatin B1 M. Mahdjoub,M. Dechir,C. Gendre,E. Dubreil,L. Le Hegaratet al. 59th Congress of the European Societies of Toxicology (EUROTOX 2025), Sep 2025, Athènes, Greece. , Toxicology letters, 411, pp.S389-S390, 2025, ⟨10.1016/j.toxlet.2025.07.897⟩ Poster de conférence anses-05460157v2
Mechanistic Modeling of Antibiotics Transfer across the Blood-Milk Barrier in Ruminants: Case Study of Marbofloxacin Marc Codaccioni,Jennifer Tardiveau,Jérôme Henri,Nicolas Grégoire,Alexis Viel 59th Congress of the European Societies of Toxicology (EUROTOX 2025) : Toxicology addresses society's real life risks for sustainable health and well being, Sep 2025, Athènes, Greece. Toxicology letters, 411, pp.S195, 2025, ⟨10.1016/j.toxlet.2025.07.468⟩ Poster de conférence hal-05251265v1
Metabolism of Enniatin B in primary mouse, rat and human hepatocytes Estelle Dubreil,Lada Ivanova,Charlène Gendre,Mariam Mahdjoub,Valérie Fessardet al. 58th Congress of the European Societies of Toxicology (EUROTOX 2024), Sep 2024, Copenhagen, Denmark. , 399, pp.S125, 2024, ⟨10.1016/j.toxlet.2024.07.322⟩ Poster de conférence anses-04701403v1
Impact of quaternary ammoniums on permeability and intestinal microbiota: a study to detect biomarkers of exposure in rats Kahina Slimani,Sophie Mompelat,Cécile Vignal,Tahar Ait-Ali,Jean-François Taillandieret al. 16èmes JS du RFMF, Jun 2024, Saint-Malo, France Poster de conférence hal-05034843v1
Complements on Enniatin B metabolism for interspecies qIVIVE and risk assessment in human Jérôme Henri,Estelle Dubreil,Valérie Fessard,Solenne Martin,Françoise Bréeet al. 57th Congress of the European Societies of Toxicology - EUROTOX 2023, Sep 2023, Ljubljana, Slovenia Poster de conférence hal-05467972v1
Assessment of the selective effect of colistin on mcr-1-positive Escherichia coli through in vitro co-culture time-kill experiments Alexis Viel,Charlotte Valentin,Jérôme Henri,Michel Laurentie,Pascal Sanders Tenth International Conference on Antimicrobial Agents in Veterinary Medicine, Nov 2020, Virtual, France Poster de conférence anses-03499578v1
Use of PBPK modeling to explore the pharmacokinetics and renal disposition of CMS/Colistin in piglets as a model for the paediatric population Alexis Viel,Jérôme Henri,William Couet,Michel Laurentie,Pascal Sanderset al. CVPT/ESVNU Symposium (European College of Veterinary Pharmacology and Therapeutics & European Society of Veterinary Nephrology and Urology): Pharmacology and the kidney, Jul 2019, London, United Kingdom Poster de conférence hal-05480054v1
Modélisation mécaniste du transfert de contaminants lipophiles chez la vache laitière : vers une meilleure maitrise de la qualité sanitaire du lait Olivier Martin,Sylvain Lerch,Agnès Fournier,Jérôme Henri Rencontres Recherches Ruminants, 2018, Paris, France Poster de conférence hal-04463527v1
Exploring the effects of dietary lipid content and digestibility on lipophilic contaminants transfer from feed to milk: insights from a Physiologically Based ToxicoKinetic model Sylvain Lerch,Olivier Martin,Agnès Fournier,Jérôme Henri 10 th International Symposium on the Nutrition of Herbivores (ISNH), Sep 2018, Clermont-Ferrand, France Poster de conférence hal-05468582v1
Lack of experimental evidence to support mcr-1-positive Escherichia coli strain selection during oral administration of colistin by gavage in weaned piglets Alexis Viel,Jérôme Henri,Agnès Perrin-Guyomard,Julian Laroche,William Couetet al. 14th international congress of the European association for veterinary pharmacology and toxicology, Jun 2018, Wroclaw, Poland. Poster de conférence anses-01985196v1
Modélisation générique du devenir d’un retardateur de flammes bromé (α-HBCD) chez le poulet de chair et le porc Bertrand Méda,Eric Royer,Stéphanie Guérin,Andrea Garcia de Salazar,Elena Dominguez-Romeroet al. 12.Journées de la recherche avicole et palmipèdes à foie gras, Apr 2017, Tours, France. 2017 Poster de conférence hal-01688926v1
The influence of age on colistin methanosulfonate and colistin plasmatic and tissular distribution after intravenous administration of colistin methanosulfonate in pigs background Alexis Viel,Nicolas Grégoire,Jérôme Henri,Patrice Gobin,Julian Larocheet al. 8th International Conference on Antimicrobial Agents in Veterinary Medicine (AAVM 2016), Aug 2016, Budapest, Hungary Poster de conférence hal-05480028v1
Fate of a brominated flame retardant (HBCD) in chickens and pigs: a generic modelling approach Bertrand Méda,Eric Royer,Stéphanie Guerin,Andrea Garcia de Salazar,Elena Dominguez-Romeroet al. 67th Annual meeting of the European Federation of Animal Science EAAP 2016, Aug 2016, Belfast, United Kingdom. , EAAP Publication, 2016, EAAP Publication Poster de conférence hal-01367303v1
Sensibilité aux désinfectants des Escherichia coli porteurs d'une résistance aux céphalosporines de 3ème génération (C3G) de type CTX-M A Perrin-Guyomard,Sarah Robiolle,Patricia Le Grandois,Béatrice Anger-Lemaitre,Catherine Poirieret al. 9ème Congrès national de la Société Française de Microbiologie (SFM), Feb 2013, Lille, France Poster de conférence hal-05477842v1
Microcystin-LR transfer through the in vitro intestinal barrier of caco-2 cells Jérôme Henri,Antoine Huguet,Aurore Besson,Jean-Michel Delmas,Valérie Fessard The 8th international conference on toxic cyanobacteria, Aug 2010, Istanbul, Turkey Poster de conférence anses-05479973v1
EFFECTS OF MICROCYSTIN LR ON THE INTEGRITY OF THE IN VITRO CACO-2 INTESTINAL BARRIER MODEL Antoine Huguet,Jérôme Henri,Aurore Besson,Valérie Fessard EUSAAT (European society for alternatives to animal testing), Sep 2010, Linz, Austria Poster de conférence anses-05479948v1

Proceedings/Recueil des communications (2)

114. Population pharmacokinetic modelling of different sulphonamides associated with trimethoprim in pigs Marine Boulanger,J.F. Taillandier,Jérôme Henri,Marlène Z Lacroix,Béatrice Roqueset al. 57th Swine Research Days [57es Journées de la Recherche Porcine] (JRP 2025), Feb 2025, Saint-Malo, France. Animal. Science proceedings, 16 (6), pp.896, 2025, ⟨10.1016/j.anscip.2025.08.115⟩ Proceedings/Recueil des communications hal-05406887v1
Population PK modeling of different sulfonamides in association with trimethoprim in pigs Alexis Viel,Marine Boulanger,Jean-François Taillandier,Michel Laurentie,Jérôme Henriet al. 15th International Congress of the European Association for Veterinary Pharmacology and Toxicology, Journal of Veterinary Pharmacology and Therapeutics, 46 (S1), pp.82-83, 2023, ⟨10.1111/jvp.13277⟩ Proceedings/Recueil des communications hal-04352560v1

Communication dans un congrès (4)

Semi-mecanistic PKPD modeling of enrofloxacin against sensitive strains of Pasteurella multocida in pigs Anthony Khaled,Jérôme Henri,Alexis Viel Twelfth International Conference on Antimicrobial Agents in Veterinary Medicine (AAVM), Jun 2024, Athènes, Greece Communication dans un congrès hal-04628898v1
A mechanistic model of lipophilic contaminants transfer in dairy cow for improve milk safety Sylvain Lerch,Olivier Martin,Agnès Fournier,Jérôme Henri 24e journées Rencontres Recherches Ruminants, 2018, Dec 2018, Paris, France. pp.425 Communication dans un congrès hal-05477706v1
Mechanistic modelling of lipophilic contaminant transfer in lactating cow from knowledge integration toward risk assessment tool for improve milk safety Sylvain Lerch,Olivier Martin,Agnès Fournier,Jérôme Henri 10th International Symposium on the Nutrition of Herbivores, Sep 2018, Clermont - Ferrand, France Communication dans un congrès hal-05477677v1
Etude des déplétions tissulaires du monensin chez le poulet et la dinde Brigitte Roudaut,Estelle Chéneau,Jérôme Henri,Christine Burel,Robert Mauriceet al. 8. Journées de la Recherche Avicole, Mar 2009, Saint Malo, France Communication dans un congrès hal-02052972v1

Rapport (3)

EFSA Pilot Project on New Approach Methodologies (NAMs) for Tebufenpyrad Risk Assessment. Part 1. Development of Physiologically‐Based Kinetic (PBK) Model Coupled With Pulmonary and Dermal Exposure Jérôme Henri,Ludovic Lehegarat,Adeline Cavelier,Bertrand Desprez EFSA. 2023 Rapport (rapport de recherche) hal-05468568v1
Rapport d'expertise collective ANSES : Actualisation des données relatives aux substances phytopharmaceutiques de la famille des inhibiteurs de la succinate déshydrogénase (SDHI) Claude Emond,Thierry Baron,Sylvie Bortoli,Frédéric Bouillaud,Thomas Claudepierreet al. ANSES. 2023 Rapport hal-04873181v1
OPINION of the French Agency for Food, Environmental and Occupational Health & Safety on &quot;Updating data on succinate dehydrogenase inhibitor (SDHI)-based plant protection substances Claude Emond,Thierry Baron,Sylvie Bortoli,Frédéric Bouillaud,Thomas Claudepierreet al. Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES). 2023, 50 p Rapport (rapport d’expertise collective) anses-05468521v1

HDR (1)

Modèles cinétiques dans le domaine des risques sanitaires liés aux contaminants chimiques de l'alimentation humaine : expérimentation et modélisation Jérôme Henri Pharmacologie. Université de Rennes 1, 2022 HDR tel-05468126v1