Jerome MOREAUX Professor CNU 87, Faculty of Medicine, University Montpellier.

Identifiants chercheurs

IdHAL :

jerome-moreaux

ORCID :

0000-0002-5717-3207

IdRef :

075698560

Publications

Article dans une revue (140)

Enhancing antitumour response to proteasome inhibitors with inhibitors of insulin‐degrading enzyme, a new molecular vulnerability in multiple myeloma Laetitia Lesire,Rebecca Deprez-Poulain,Damien Bosc,Florence Leroux,Valerie Landryet al. British Journal of Pharmacology, 2026, ⟨10.1111/bph.70407⟩ Article dans une revue hal-05559143v1
Targeting transcription-replication conflicts using G-quadruplexes stabilizers in multiple myeloma Laure Dutrieux,Sara Ovejero,Antoine Guillemin,Miss Leriem Zellagui,Elke de Bruyneet al. Blood Neoplasia, 2025, 2 (2), pp.100072. ⟨10.1016/j.bneo.2025.100072⟩ Article dans une revue hal-05343640v1
Synergistic effect of inhibiting CHK2 and DNA replication on cancer cell growth Flavie Coquel,Sing-Zong Ho,Keng-Chang Tsai,Chun-Yen Yang,Antoine Azeet al. eLife, 2025, 13, pp.RP104718. ⟨10.7554/eLife.104718⟩ Article dans une revue hal-05378520v1
The de novo DNA methyltransferase 3B is a novel epigenetic regulator of MYC in multiple myeloma, representing a promising therapeutic target to counter relapse Catharina Muylaert,Lien Ann van Hemelrijck,Arne van der Vreken,Robbe Heestermans,Hatice Satilmiset al. Journal of experimental & clinical cancer research, 2025, 44 (1), pp.125. ⟨10.1186/s13046-025-03382-y⟩ Article dans une revue hal-05523791v1
Development of a robust BH3 drug toolkit for precision medicine in hematologic malignancies Valentin Jacquier,Andréa Romero,Caroline Molinaro,Ritu Somayaji,Matthieu Abouladzeet al. Theranostics, 2025, 15 (12), pp.5705-5718. ⟨10.7150/thno.107852⟩ Article dans une revue hal-05521232v1
PIM2 inhibition promotes MCL1 dependency in plasma cells involving integrated stress response-driven NOXA expression Marion Haas,Sabrina Cherfa,Léa Nguyen,Maxence Bourgoin,Gersende Caronet al. Nature Communications, 2025, 16 (1), pp.256. ⟨10.1038/s41467-024-55572-5⟩ Article dans une revue hal-04883435v1
Synthetic Lethal Combinations of DNA Repair Inhibitors and Genotoxic Agents to Target High‐Risk Diffuse Large B Cell Lymphoma Sara Ovejero,Julie Devin,Laura Alibert,Camille Soun,Yea‐lih Linet al. Hematological Oncology, 2025, 43 (5), pp.e70131. ⟨10.1002/hon.70131⟩ Article dans une revue hal-05515319v1
Ironomycin induces mantle cell lymphoma cell death by targeting iron metabolism addiction Sara Ovejero,Laura Alibert,Julie Devin,Tatiana Cañeque,Valentin Jacquieret al. Theranostics, 2025, 15 (7), pp.2834-2851. ⟨10.7150/thno.101821⟩ Article dans une revue hal-05343829v1
Editing B cells at the IGHA2 gene position provides alternative route to therapeutic IgA production Marine Cahen,Jenny Leonard,Ophélie Dézé,Laurent Deleurme,Maïwenn Pineauet al. Mucosal Immunology, 2025, 18 (5), pp.1027-1035. ⟨10.1016/j.mucimm.2025.06.001⟩ Article dans une revue hal-05163114v1
DIS3 licenses B cells for plasma cell differentiation in humans Emma Miglierina,Julien Bouder,Delfina Ordanoska,Maïwenn Pineau,Simon Leonardet al. Cellular and molecular immunology, 2025, 23 (1), pp.31-47. ⟨10.1038/s41423-025-01369-5⟩ Article dans une revue hal-05417577v1
CD200 immune checkpoint expression is associated with inferior outcome in multiple myeloma patients treated with anti-CD38 monoclonal antibodies Djamila Chemlal,Camille Pochard,Valentin Jacquier,Angélique Bruyer,Ludovic Gabellieret al. OncoImmunology, 2025, 14 (1), pp.2532226. ⟨10.1080/2162402X.2025.2532226⟩ Article dans une revue hal-05527272v1
A case of refractory IgG4-related disease successfully treated with daratumumab and lenalidomide Denis Coulomb,Vanessa Lacheretz-Szablewski,Nicolas Robert,Anne-Marie Dupuy,Rayane Berrahouaneet al. Rheumatology, 2024, 64 (2), pp.895-897. ⟨10.1093/rheumatology/keae448⟩ Article dans une revue hal-04704591v1
Integrative single-cell chromatin and transcriptome analysis of human plasma cell differentiation Elina Alaterre,Sara Ovejero,Caroline Bret,Laure Dutrieux,Dassou Sikaet al. Blood, 2024, 144 (5), pp.496-509. ⟨10.1182/blood.2023023237⟩ Article dans une revue hal-04701434v1
BHLHE41, a transcriptional repressor involved in physiological processes and tumor development Caroline Bret,Fabienne Desmots-Loyer,Jérôme Moreaux,Thierry Fest Cellular Oncology, 2024, 48, pp.43-66. ⟨10.1007/s13402-024-00973-3⟩ Article dans une revue hal-04704590v1
FCGR3A F158V alleles frequency differs in multiple myeloma patients from healthy population Michaël Constantinides,Nicolas Robert,Caroline Multrier,Loïs Coënon,Mauricio Campos-Moraet al. OncoImmunology, 2024, 13 (1), pp.2388306. ⟨10.1080/2162402X.2024.2388306⟩ Article dans une revue hal-04704594v1
Transient loss of Polycomb components induces an epigenetic cancer fate Victoria Parreno,Vincent Loubiere,Bernd Schuettengruber,Lauriane Fritsch,Chetan C. Rawalet al. Nature, 2024, 629 (8012), pp.688-696. ⟨10.1038/s41586-024-07328-w⟩ Article dans une revue hal-04581411v1
CD38 , CD39 , and BCL2 differentiate disseminated forms of high‐grade B‐cell lymphomas in biological fluids from Burkitt lymphoma and diffuse large B‐cell lymphoma Pauline Marianini,Vanessa Lacheretz-Szablewski,Marion Almeras,Jérôme Moreaux,Caroline Bret Cytometry Part B: Clinical Cytometry, 2024, 144 (5), pp.496-509. ⟨10.1002/cyto.b.22208⟩ Article dans une revue hal-04704587v1
Single-hit genome editing optimized for maturation in B cells redirects their specificity toward tumor antigens Natsuko Ueda,Marine Cahen,Jenny Leonard,Laurent Deleurme,Stéphane Dreanoet al. Scientific Reports, 2024, 14 (1), pp.22432. ⟨10.1038/s41598-024-74005-3⟩ Article dans une revue hal-04723581v1
Quantitative Integrative Survival Prediction in Multiple Myeloma Patients Treated With Bortezomib-Based Induction, High-Dose Therapy and Autologous Stem Cell Transplantation Manuela Hummel,Thomas Hielscher,Martina Emde-Rajaratnam,Hans Salwender,Susanne Becket al. JCO precision oncology, 2024, 8, pp.e2300613. ⟨10.1200/PO.23.00613⟩ Article dans une revue hal-04704595v1
MRE11 and TREX1 control senescence by coordinating replication stress and interferon signaling Hervé Técher,Diyavarshini Gopaul,Jonathan Heuzé,Nail Bouzalmad,Baptiste Lerayet al. Nature Communications, 2024, 15 (1), pp.5423. ⟨10.1038/s41467-024-49740-w⟩ Article dans une revue hal-04748159v1
An atlas of cells in the human tonsil Ramon Massoni-Badosa,Sergio Aguilar-Fernández,Juan C. Nieto,Paula Soler-Vila,Marc Elosua-Bayeset al. Immunity, 2024, 57 (2), pp.379-399.e18. ⟨10.1016/j.immuni.2024.01.006⟩ Article dans une revue hal-04704602v1
KDM6A controls immunogenicity in MM Jerome Moreaux Blood, 2024, 144 (14), pp.1465-1467. ⟨10.1182/blood.2024026013⟩ Article dans une revue hal-04912732v1
Combined inhibition of Wee1 and Chk1 as a therapeutic strategy in multiple myeloma Angélique Bruyer,Laure Dutrieux,Hugues de Boussac,Thibaut Martin,Djamila Chemlalet al. Frontiers in Oncology, 2023, 13, pp.1271847. ⟨10.3389/fonc.2023.1271847⟩ Article dans une revue hal-04704603v1
Var∣Decrypt: a novel and user-friendly tool to explore and prioritize variants in whole-exome sequencing data Mohammad Salma,Elina Alaterre,Jérôme Moreaux,Eric Soler Epigenetics & Chromatin, 2023, 16 (1), pp.23. ⟨10.1186/s13072-023-00497-4⟩ Article dans une revue hal-04705018v1
Editorial: Transcriptional control in normal and malignant B-lymphocytes Jérôme Moreaux,Alexander A. Shtil Frontiers in Immunology, 2023, 14, pp.1185252. ⟨10.3389/fimmu.2023.1185252⟩ Article dans une revue hal-04705020v1
RNA-sequencing based first choice of treatment and determination of risk in multiple myeloma Martina Emde-Rajaratnam,Susanne Beck,Vladimir Benes,Hans Salwender,Uta Bertschet al. Frontiers in Immunology, 2023, 14, pp.1286700. ⟨10.3389/fimmu.2023.1286700⟩ Article dans une revue hal-04704606v1
Immunophenotypic portrait of leukemia‐associated‐phenotype markers in B acute lymphoblastic leukemia Emilia Boris,Alexandre Theron,Valentin Montagnon,Nicolas Rouquier,Marion Almeraset al. Cytometry Part B: Clinical Cytometry, 2023, 106 (1), pp.45-57. ⟨10.1002/cyto.b.22153⟩ Article dans une revue hal-04704605v1
3-O sulfation of syndecan-1 mediated by the sulfotransferase HS3ST3a1 enhances myeloma aggressiveness L. Baert,B. Manfroi,M. Quintero,O. Chavarria,P.V. Barbonet al. Matrix Biology, 2023, 120, pp.60-75. ⟨10.1016/j.matbio.2023.05.005⟩ Article dans une revue hal-04444452v1
Extreme thrombocytosis with an aggressive evolution harboring a novel variant of calreticulin (CALR) in exon 3 Sarah Bonnet,Serge Carillo,Baptiste Legrand,Barbara Burroni,Thierry Lavabre-Bertrandet al. European Journal of Haematology, 2023, 112 (3), pp.475-478. ⟨10.1111/ejh.14126⟩ Article dans une revue hal-04550049v1
S-adenosylmethionine biosynthesis is a targetable metabolic vulnerability in multiple myeloma Yanmeng Wang,Catharina Muylaert,Arne Wyns,Philip Vlummens,Kim de Veirmanet al. Haematologica, 2023, 109, pp.256-271. ⟨10.3324/haematol.2023.282866⟩ Article dans une revue hal-04705017v1
EZH2 targeting induces CD38 upregulation and response to anti-CD38 immunotherapies in multiple myeloma Djamila Chemlal,Emmanuel Varlet,Amelie Machura,Sara Ovejero,Guilhem Requirandet al. Leukemia, 2023, 37 (9), pp.1925-1928. ⟨10.1038/s41375-023-01983-0⟩ Article dans une revue hal-04252294v1
LAIR1, an ITIM-Containing Receptor Involved in Immune Disorders and in Hematological Neoplasms François van Laethem,Lucie Donaty,Emmanuelle Tchernonog,Vanessa Lacheretz-Szablewski,Jennifer Russelloet al. International Journal of Molecular Sciences, 2022, 23 (24), pp.16136. ⟨10.3390/ijms232416136⟩ Article dans une revue hal-03980144v1
Targeting Cellular Iron Homeostasis with Ironomycin in Diffuse Large B-cell Lymphoma Julie Devin,Tatiana Cañeque,Yea-Lih Lin,Lucie Mondoulet,Jean-Luc Veyruneet al. Cancer Research, 2022, 82 (6), pp.998-1012. ⟨10.1158/0008-5472.CAN-21-0218⟩ Article dans une revue hal-04053839v1
PIM2 kinase has a pivotal role in plasmablast generation and plasma cell survival, opening up novel treatment options in myeloma Marion Haas,Gersende Caron,Fabrice Chatonnet,Stéphane Manenti,Elina Alaterreet al. Blood, 2022, 139 (15), pp.2316-2337. ⟨10.1182/blood.2021014011⟩ Article dans une revue hal-04822853v2
Comprehensive characterization of the epigenetic landscape in Multiple Myeloma Elina Alaterre,Sara Ovejero,Laurie Herviou,Hugues de Boussac,Giorgio Papadopouloset al. Theranostics, 2022, 12 (4), pp.1715-1729. ⟨10.7150/thno.54453⟩ Article dans une revue hal-03810219v1
miRNA profile at diagnosis predicts treatment outcome in patients with B-chronic lymphocytic leukemia: A FILO study Isabelle Duroux-Richard,Anne-Laure Gagez,Elina Alaterre,Rémi Letestu,Olfa Khalifaet al. Frontiers in Immunology, 2022, 13, pp.983771. ⟨10.3389/fimmu.2022.983771⟩ Article dans une revue hal-03946290v1
The BLM helicase is a new therapeutic target in multiple myeloma involved in replication stress survival and drug resistance Sara Ovejero,Elena Viziteu,Laure Dutrieux,Julie Devin,Yea-Lih Linet al. Frontiers in Immunology, 2022, 13, pp.983181. ⟨10.3389/fimmu.2022.983181⟩ Article dans une revue (data paper) hal-04021632v1
The NADPH oxidase NOX2 is a marker of adverse prognosis involved in chemoresistance of acute myeloid leukemias Rosa Paolillo,Mathias Boulanger,Pierre Gâtel,Ludovic Gabellier,Marion de Toledoet al. Haematologica, 2022, 107 (11), pp.2562-2575. ⟨10.3324/haematol.2021.279889⟩ Article dans une revue hal-03759821v2
Targeting the β 2 ‐adrenergic receptor increases chemosensitivity in multiple myeloma by induction of apoptosis and modulating cancer cell metabolism Hatice Satilmis,Emma Verheye,Philip Vlummens,Inge Oudaert,Niels Vandewalleet al. Journal of Pathology, 2022, 259 (1), pp.69-80. ⟨10.1002/path.6020⟩ Article dans une revue hal-04590992v1
Inhibition of the Protein Arginine Methyltransferase PRMT5 in High-Risk Multiple Myeloma as a Novel Treatment Approach Philip Vlummens,Stefaan Verhulst,Kim de Veirman,Anke Maes,Eline Menuet al. Frontiers in Cell and Developmental Biology, 2022, 10, ⟨10.3389/fcell.2022.879057⟩ Article dans une revue hal-04705562v1
RNA-Sequencing-Based Transcriptomic Score with Prognostic and Theranostic Values in Multiple Myeloma Elina Alaterre,Veronika Vikova,Alboukadel Kassambara,Angélique Bruyer,Nicolas Robertet al. Journal of Personalized Medicine, 2021, 11 (10), pp.988. ⟨10.3390/jpm11100988⟩ Article dans une revue hal-03639307v1
Clinical Correlations of Polycomb Repressive Complex 2 in Different Tumor Types Maksim Erokhin,Olga Chetverina,Balázs Győrffy,Victor Tatarskiy,Vladic Mogilaet al. Cancers, 2021, 13 (13), pp.3155. ⟨10.3390/cancers13133155⟩ Article dans une revue hal-03693300v1
The microenvironment of DLBCL is characterized by noncanonical macrophages recruited by tumor-derived CCL5 Benoît Manfroi,Maria de Grandis,Jérôme Moreaux,Sébastien Tabruyn,Jean-François Mayolet al. Blood Advances, 2021, 5 (21), pp.4338-4351. ⟨10.1182/bloodadvances.2021004203⟩ Article dans une revue hal-04444537v1
The origin of pre-plasmablastic cells Jerome Moreaux Blood, 2021, 137 (9), pp.1134-1135. ⟨10.1182/blood.2020009746⟩ Article dans une revue hal-03243758v1
Targeting the methyltransferase SETD8 impairs tumor cell survival and overcomes drug resistance independently of p53 status in multiple myeloma Laurie Herviou,Sara Ovejero,Fanny Izard,Ouissem Karmous-Gadacha,Claire Gourzoneset al. Clinical Epigenetics, 2021, 13 (1), ⟨10.1186/s13148-021-01160-z⟩ Article dans une revue hal-03450559v1
Discovery of candidate DNA methylation cancer driver genes Heng Pan,Loic Renaud,Ronan Chaligne,Johannes Bloehdorn,Eugen Tauschet al. Cancer Discovery, 2021, pp.candisc.1334.2020. ⟨10.1158/2159-8290.CD-20-1334⟩ Article dans une revue hal-03243749v1
RNA Sequencing Data-driven Dissection of Human Plasma Cell Differentiation Reveals New Potential Transcription Regulators Alboukadel Kassambara,Laurie Herviou,Sara Ovejero,Michel Jourdan,Coraline Thibautet al. Leukemia, 2021, 35 (5), pp.1451-1462. ⟨10.1038/s41375-021-01234-0⟩ Article dans une revue hal-03243729v1
Transcription/Replication Conflicts in Tumorigenesis and Their Potential Role as Novel Therapeutic Targets in Multiple Myeloma Laure Dutrieux,Yea-Lih Lin,Malik Lutzmann,Raphaël Rodriguez,Michel Cognéet al. Cancers, 2021, 13 (15), pp.3755. ⟨10.3390/cancers13153755⟩ Article dans une revue hal-03365519v1
Immunotherapy perspectives in the new era of B-cell editing Natsuko Ueda,Marine Cahen,Yannic Danger,Jérôme Moreaux,Christophe Siracet al. Blood Advances, 2021, 5 (6), pp.1770-1779. ⟨10.1182/bloodadvances.2020003792⟩ Article dans une revue hal-03202338v1
G9a/GLP targeting in MM promotes autophagy-associated apoptosis and boosts proteasome inhibitor–mediated cell death Eva de Smedt,Julie Devin,Catharina Muylaert,Nicolas Robert,Guilhem Requirandet al. Blood Advances, 2021, 5 (9), pp.2325-2338. ⟨10.1182/bloodadvances.2020003217⟩ Article dans une revue hal-03243723v1
Angiogenic factors could help us to define patients obtaining complete response with undetectable minimal residual disease in untreated CLL patients treated by FCR: results from the CLL2010FMP, a FILO study Anne-Laure Gagez,Franciane Paul,Elina Alaterre,Valérie Gouilleux-Gruart,Edouard Tuaillonet al. Leukemia & lymphoma, 2021, 62 (13), pp.3160-3169. ⟨10.1080/10428194.2021.1955879⟩ Article dans une revue hal-03640354v1
Dihydropyrimidinase protects from DNA replication stress caused by cytotoxic metabolites J. Basbous,Antoine Aze,Laurent Chaloin,Rana Lebdy,Dana Hodrojet al. Nucleic Acids Research, 2020, 48 (4), pp.1886-1904. ⟨10.1093/nar/gkz1162⟩ Article dans une revue hal-02556387v1
Characterization of immortalized human islet stromal cells reveals a MSC-like profile with pancreatic features Orianne Villard,Mathieu Armanet,Guilhem Couderc,Claire Bony,Jerome Moreauxet al. Stem Cell Research and Therapy, 2020, 11, pp.158. ⟨10.1186/s13287-020-01649-z⟩ Article dans une revue hal-02961501v1
DNA Repair Expression Profiling to Identify High-Risk Cytogenetically Normal Acute Myeloid Leukemia and Define New Therapeutic Targets Ludovic Gabellier,Caroline Bret,Guillaume Bossis,Guillaume Cartron,Jérôme Moreaux Cancers, 2020, 12 (10), pp.2874. ⟨10.3390/cancers12102874⟩ Article dans une revue hal-03014671v1
Kinome expression profiling to target new therapeutic avenues in multiple myeloma Hugues de Boussac,Angelique Bruyer,Michel Jourdan,Anke Maes,Nicolas N. Robertet al. Haematologica, 2020, 105 (3), pp.784-795. ⟨10.3324/haematol.2018.208306⟩ Article dans une revue hal-02587620v1
A Retrospective Comparison of DLI and gDLI for Post-Transplant Treatment Sylvain Lamure,Franciane Paul,Anne-Laure Gagez,Jérémy Delage,Laure Vincentet al. Journal of Clinical Medicine, 2020, 9 (7), pp.2204. ⟨10.3390/jcm9072204⟩ Article dans une revue hal-03203259v1
The hydroxymethylome of multiple myeloma identifies FAM72D as a 1q21 marker linked to proliferation Fabrice Chatonnet,Amandine Pignarre,Aurelien Serandour,Gersende Caron,Stéphane Avneret al. Haematologica, 2020, 105 (3), pp.774-783. ⟨10.3324/haematol.2019.222133⟩ Article dans une revue hal-02165596v1
Role of Polycomb Complexes in Normal and Malignant Plasma Cells Emmanuel Varlet,Sara Ovejero,Anne-Marie Martinez,Giacomo Cavalli,Jerome Moreaux International Journal of Molecular Sciences, 2020, 21 (21), pp.8047. ⟨10.3390/ijms21218047⟩ Article dans une revue hal-03243763v1
RNA-Sequencing Based Assessment of Targets, Risk and Long Term Survival for Personalized Treatment of Multiple Myeloma Martina Emde,Susanne Beck,Vladimir Benes,Jerome Moreaux,Anja Seckingeret al. Blood, 2019, 134 (Supplement_1), pp.1801-1801. ⟨10.1182/blood-2019-131159⟩ Article dans une revue hal-05529873v1
EZH2 is overexpressed in transitional preplasmablasts and is involved in human plasma cell differentiation Laurie Herviou,Michel Jourdan,Anne-Marie Martinez,Giacomo Cavalli,Jerome Moreaux Leukemia, 2019, 33 (8), pp.2047-2060. ⟨10.1038/s41375-019-0392-1⟩ Article dans une revue hal-03243777v1
Antioxidant Defenses Confer Resistance to High Dose Melphalan in Multiple Myeloma Cells Claire Gourzones,Céline Bellanger,Sylvain Lamure,Ouissem Karmous Gadacha,Elvira Garcia de Pacoet al. Cancers, 2019, 11 (4), pp.439. ⟨10.3390/cancers11040439⟩ Article dans une revue hal-02870153v1
Treatment May Be Harmful: Mechanisms/Prediction/Prevention of Drug-Induced DNA Damage and Repair in Multiple Myeloma Claire Gourzones,Caroline Bret,Jérôme Moreaux Frontiers in Genetics, 2019, 10, pp.861. ⟨10.3389/fgene.2019.00861⟩ Article dans une revue hal-02552817v1
Prospective target assessment and multimodal prediction of survival for personalized and risk-adapted treatment strategies in multiple myeloma in the GMMG-MM5 multicenter trial Dirk Hose,Susanne Beck,Hans Salwender,Martina Emde,Uta Bertschet al. Journal of Hematology and Oncology, 2019, 12, pp.65. ⟨10.1186/s13045-019-0750-5⟩ Article dans une revue hal-03243769v1
Maternal embryonic leucine zipper kinase is a novel target for diffuse large B cell lymphoma and mantle cell lymphoma Anke Maes,Ken Maes,Philip Vlummens,Hendrik de Raeve,Julie Devinet al. Blood Cancer Journal, 2019, 9 (12), ⟨10.1038/s41408-019-0249-x⟩ Article dans une revue hal-02542010v1
Ironomycin Induces Diffuse Large B-Cell Lymphoma Cell Death By Targeting Iron Metabolism Addiction Julie Devin,Tatiana Cañeque,Yea-Lih Lin,Guillaume Cartron,Philippe Paseroet al. Blood, 2019, 134 (Supplement_1), pp.3960-3960. ⟨10.1182/blood-2019-129954⟩ Article dans une revue hal-05529967v1
Overexpression of Claspin and Timeless protects cancer cells from replication stress in a checkpoint-independent manner Julien Bianco,Valérie Bergoglio,Yea-Lih Lin,Marie-Jeanne Pillaire,Anne-Lyne Schmitzet al. Nature Communications, 2019, 10 (1), pp.910. ⟨10.1038/s41467-019-08886-8⟩ Article dans une revue hal-02047561v1
Comprehensive characterization of the mutational landscape in multiple myeloma cell lines reveals potential drivers and pathways associated with tumor progression and drug resistance Veronika Vikova,Michel Jourdan,Nicolas Robert,Guilhem Requirand,Stephanie Boireauet al. Theranostics, 2019, 9 (2), pp.540-553. ⟨10.7150/thno.28374⟩ Article dans une revue hal-02883457v1
Myeloid-derived suppressor cells induce multiple myeloma cell survival by activating the AMPK pathway Kim de Veirman,Eline Menu,Ken Maes,Nathan de Beule,Eva de Smedtet al. Cancer Letters, 2019, 442, pp.233-241. ⟨10.1016/j.canlet.2018.11.002⟩ Article dans une revue hal-01980419v1
The Anaphase-Promoting Complex/Cyclosome: A New Promising Target in Diffuse Large B-cell Lymphoma and Mantle Cell Lymphoma Anke Maes,Ken Maes,Hendrik de Raeve,Eva de Smedt,Philip Vlummenset al. British Journal of Cancer, 2019, 120 (12), pp.1137--1146. ⟨10.1038/s41416-019-0471-0⟩ Article dans une revue hal-02862214v1
Targeting the methyltransferase SETD8 impairs tumor cell survival and overcomes drug resistance independently of p53 status in multiple myeloma Laurie Herviou,Fanny Izard,Ouissem Karmous-Gadacha,Claire Gourzones,Celine Bellangeret al. BioRxiv, In press, ⟨10.1101/776930⟩ Article dans une revue hal-02355848v1
Anticorps anti-CD38 dans le myélome multiple Jérôme Moreaux Médecine/Sciences, 2019, 35 (12), pp.1001-1004. ⟨10.1051/medsci/2019198⟩ Article dans une revue hal-03243767v1
In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells Michel Jourdan,Hugues de Boussac,Elena Viziteu,Alboukadel Kassambara,Jérôme Moreaux Journal of visualized experiments : JoVE, 2019, 143, ⟨10.3791/58929⟩ Article dans une revue hal-05510019v1
Prediction of Malingant Plasma Cell Biology Related Survival in AL-Amyloidosis Susanne Beck,Martina Emde,Jerome Moreaux,Anja Seckinger,Dirk Hose Blood, 2019, 134 (Supplement_1), pp.3078-3078. ⟨10.1182/blood-2019-131161⟩ Article dans une revue hal-05530335v1
Inhibition of Ataxia-Telangiectasia Mutated and RAD3-Related ( ATR ) Overcomes Oxaliplatin Resistance and Promotes Antitumor Immunity in Colorectal Cancer Eve Combès,Augusto Andrade,Diego Tosi,Henri-Alexandre Michaud,Flavie Coquelet al. Cancer Research, 2019, 79 (11), pp.2933-2946. ⟨10.1158/0008-5472.CAN-18-2807⟩ Article dans une revue hal-02361669v1
Phenotypic Characterization of Diffuse Large B-Cell Lymphoma Cells and Prognostic Impact Julie Devin,Alboukadel Kassambara,Angelique Bruyer,Jérôme Moreaux,Caroline Bret Journal of Clinical Medicine, 2019, 8 (7), pp.1074. ⟨10.3390/jcm8071074⟩ Article dans une revue hal-02571739v1
DNMTi/HDACi combined epigenetic targeted treatment induces reprogramming of myeloma cells in the direction of normal plasma cells Angelique Bruyer,Ken Maes,Laurie Herviou,Alboukadel Kassambara,Anja Seckingeret al. British Journal of Cancer, 2018, 118 (8), pp.1062 - 1073. ⟨10.1038/s41416-018-0025-x⟩ Article dans une revue hal-01792246v1
An epigenetic regulator-related score (EpiScore) predicts survival in patients with diffuse large B cell lymphoma and identifies patients who may benefit from epigenetic therapy Vanessa Szablewski,Caroline Bret,Alboukadel Kassambara,Julie Devin,Guillaume Cartronet al. Oncotarget, 2018, 9 (27), pp.19079--19099. ⟨10.18632/oncotarget.24901⟩ Article dans une revue hal-02345949v1
Loss of RASSF4 Expression in Multiple Myeloma Promotes RAS-Driven Malignant Progression Eva de Smedt,Ken Maes,Stefaan Verhulst,Hui Lui,Alboukadel Kassambaraet al. Cancer Research, 2018, 78 (5), pp.1155 - 1168. ⟨10.1158/0008-5472.CAN-17-1544⟩ Article dans une revue hal-01864144v1
PRC2 targeting is a therapeutic strategy for EZ score defined high-risk multiple myeloma patients and overcome resistance to IMiDs Laurie Herviou,Alboukadel Kassambara,Stéphanie Boireau,Nicolas Robert,Guilhem Requirandet al. Clinical Epigenetics, 2018, 10, pp.121. ⟨10.1186/s13148-018-0554-4⟩ Article dans une revue hal-02315111v1
BrdU incorporation in multiparameter flow cytometry: A new cell cycle assessment approach in multiple myeloma Guilhem Requirand,Nicolas Robert,Stéphanie Boireau,Laure Vincent,Anja Seckingeret al. Cytometry Part B: Clinical Cytometry, 2018, ⟨10.1002/cyto.b.21730⟩ Article dans une revue hal-02048196v1
[EZH2 is therapeutic target for personalized treatment in multiple myeloma]. Laurie Herviou,Giacomo Cavalli,Jérôme Moreaux Bulletin du Cancer, 2018, 105 (9), pp.804 - 819. ⟨10.1016/j.bulcan.2018.06.003⟩ Article dans une revue hal-01904689v1
Physiological and druggable skipping of immunoglobulin variable exons in plasma cells Mohamad Omar Ashi,Nivine Srour,Jean-Marie Lambert,Anne Marchalot,Ophélie Martinet al. Cellular and molecular immunology, 2018, ⟨10.1038/s41423-018-0160-6⟩ Article dans une revue hal-02048156v1
Tumor-associated neutrophils correlate with poor prognosis in diffuse large B-cell lymphoma patients B. Manfroi,J. Moreaux,C. Righini,F. Ghiringhelli,N. Sturmet al. Blood Cancer Journal, 2018, 8 (7), pp.66. ⟨10.1038/s41408-018-0099-y⟩ Article dans une revue hal-01859413v1
Global miRNA expression analysis identifies novel key regulators of plasma cell differentiation and malignant plasma cell A Kassambara,M Jourdan,A Bruyer,N Robert,V Pantescoet al. Nucleic Acids Research, 2017, 45 (10), pp.5639-5652. ⟨10.1093/nar/gkx327⟩ Article dans une revue hal-01533425v1
Automated and simplified identification of normal and abnormal plasma cells in Multiple Myeloma by flow cytometry Elina Alaterre,Sébastien Raimbault,Jean-Michel Garcia,Thierry Rème,Guilhem Requirandet al. Cytometry Part B: Clinical Cytometry, 2017, ⟨10.1002/cyto.b.21590⟩ Article dans une revue hal-01680330v1
RECQ1 helicase is involved in replication stress survival and drug resistance in multiple myeloma E Viziteu,B Klein,J. Basbous,Yea-Lih Lin,Christophe Hirtzet al. Leukemia, 2017, 31 (10), pp.2104 - 2113. ⟨10.1038/leu.2017.54⟩ Article dans une revue hal-01630891v1
Hypoxia favors the generation of human plasma cells M Schoenhals,M Jourdan,A Bruyer,A Kassambara,B Kleinet al. Cell Cycle, 2017, 1, pp.14. ⟨10.1080/15384101.2017.1317408⟩ Article dans une revue hal-01529310v1
Characterization of human FCRL4-positive B cells Michel Jourdan,Nicolas Robert,Maïlys Cren,Coraline Thibaut,Christophe Duperrayet al. PLoS ONE, 2017, 12 (6), pp.e0179793. ⟨10.1371/journal.pone.0179793⟩ Article dans une revue hal-01560458v1
Chetomin, targeting HIF-1α/p300 complex, exhibits antitumour activity in multiple myeloma Elena Viziteu,Camille Grandmougin,Harmut Goldschmidt,Anja Seckinger,Dirk Hoseet al. British Journal of Cancer, 2016, 114 (5), pp.519-523. ⟨10.1038/bjc.2016.20⟩ Article dans une revue hal-01284314v1
RECQ helicases are deregulated in hematological malignancies in association with a prognostic value Elena Viziteu,Alboukadel Kassambara,Philippe Pasero,Bernard Klein,Jerome Moreaux Biomarker Research, 2016, 4, pp.3. ⟨10.1186/s40364-016-0057-4⟩ Article dans une revue inserm-01322505v1
Identifying high-risk adult AML patients: epigenetic and genetic risk factors and their implications for therapy C Bret,E Viziteu,A Kassambara,J Moreaux Expert Review of Hematology, 2016, 9 (4), pp.351-360. ⟨10.1586/17474086.2016.1141673⟩ Article dans une revue hal-01299313v1
Inhibiting the anaphase promoting complex/cyclosome induces a metaphase arrest and cell death in multiple myeloma cells S Lub,A Maes,K Maes,K de Veirman,E de Bruyneet al. Oncotarget, 2016, 7 (4), pp.4061-4076. ⟨10.18632/oncotarget.6768⟩ Article dans une revue hal-01299387v1
Differential effects of lenalidomide during plasma cell differentiation Michel Jourdan,Maïlys Cren,Peter A Schäfer,Nicolas Robert,Christophe Duperrayet al. Oncotarget, 2016, 7 (19), pp.28096-28111. ⟨10.18632/oncotarget.8581⟩ Article dans une revue hal-01355076v1
EZH2 in normal hematopoiesis and hematological malignancies Laurie Herviou,Giacomo Cavalli,Guillaume Cartron,Bernard Klein,Jérôme Moreaux Oncotarget, 2016, 7 (3), pp.2284-2296. ⟨10.18632/oncotarget.6198⟩ Article dans une revue hal-01275235v1
Drug metabolism and clearance system in tumor cells of patients with multiple myeloma Wafa Hassen,Alboukadel Kassambara,Thierry Rème,S Sahota,A Seckingeret al. Oncotarget, 2015, 6 (8), pp.6431-6447. ⟨10.18632/oncotarget.3237⟩ Article dans une revue hal-01153138v1
Factors influencing extramedullary relapse after allogeneic transplantation for multiple myeloma L. Vincent,P. Ceballos,Carine Plassot,J. C. Méniane,P. Quittetet al. Blood Cancer Journal, 2015, 5 (8), pp.e341-e341. ⟨10.1038/bcj.2015.48⟩ Article dans une revue hal-01955536v1
miRNAs in multiple myeloma - a survival relevant complex regulator of gene expression A Seckinger,T Meissner,Jérôme Moreaux,V. Benes,J Hillengasset al. Oncotarget, 2015, 6 (36), pp.39165-39183. ⟨10.18632/oncotarget.5381⟩ Article dans une revue hal-01237028v1
Expression and role of RIP140/NRIP1 in chronic lymphocytic leukemia Marion Lapierre,Audrey Castet-Nicolas,Delphine Gitenay,Stéphan Jalaguier,Catherine Teyssieret al. Journal of Hematology and Oncology, 2015, 8 (1), pp.20. ⟨10.1186/s13045-015-0116-6⟩ Article dans une revue hal-01153157v1
In vivo treatment with epigenetic modulating agents induces transcriptional alterations associated with prognosis and immunomodulation in multiple myeloma K Maes,E de Smedt,A Kassambara,D Hose,A Seckingeret al. Oncotarget, 2015, 6 (5), pp.3319-3334. ⟨10.18632/oncotarget.3207⟩ Article dans une revue hal-01153601v1
DNA repair in diffuse large B-cell lymphoma: a molecular portrait Caroline Bret,Bernard Klein,Guillaume Cartron,Jean-François Schved,Angelos Constantinouet al. British Journal of Haematology, 2015, 169 (2), pp.296-299. ⟨10.1111/bjh.13206⟩ Article dans une revue hal-01143993v1
The 7p15.3 (rs4487645) association for multiple myeloma shows strong allele-specific regulation of the MYC-interacting gene CDCA7L in malignant plasma cells Niels Weinhold,Tobias Meissner,David Johnson,Anja Seckinger,Jerome Moreauxet al. Haematologica, 2015, 100 (3), pp.e110-e113. ⟨10.3324/haematol.2014.118786⟩ Article dans une revue hal-02157564v1
A DNA repair pathway score predicts survival in human multiple myeloma: the potential for therapeutic strategy Alboukadel Kassambara,Claire Gourzones,S. Sahota,Thierry Rème,Jérôme Moreauxet al. Oncotarget, 2014, 5 (9), pp.2487-2498. ⟨10.18632/oncotarget.1740⟩ Article dans une revue hal-01006634v1
DNA methylation score is predictive of myeloma cell sensitivity to 5-azacitidine. Jérôme Moreaux,Angelique Bruyer,Jean-Luc Veyrune,Hartmut Goldschmidt,Dirk Hoseet al. British Journal of Haematology, 2014, 164 (4), pp.613-6. ⟨10.1111/bjh.12660⟩ Article dans une revue inserm-00906054v1
Identification of a 20-gene expression-based risk score as a predictor of clinical outcome in chronic lymphocytic leukemia patients. Elias Bou Samra,Bernard Klein,Thérèse Commes,Jérôme Moreaux BioMed Research International , 2014, 2014, pp.423174. ⟨10.1155/2014/423174⟩ Article dans une revue inserm-01023921v1
Nucleotide excision DNA repair pathway as a therapeutic target in patients with high-risk diffuse large B cell lymphoma. Caroline Bret,Bernard Klein,Jérôme Moreaux Cell Cycle, 2013, 12 (12), pp.1811-2. ⟨10.4161/cc.25115⟩ Article dans une revue inserm-00840265v1
Inhibition of DEPDC1A, a bad prognostic marker in multiple myeloma, delays growth and induces mature plasma cell markers in malignant plasma cells. Alboukadel Kassambara,Matthieu Schoenhals,Jérôme Moreaux,Jean-Luc Veyrune,Thierry Rèmeet al. PLoS ONE, 2013, 8 (4), pp.e62752. ⟨10.1371/journal.pone.0062752⟩ Article dans une revue inserm-00840268v1
Gene expression-based prediction of myeloma cell sensitivity to histone deacetylase inhibitors. Jérôme Moreaux,Thierry Rème,Wim Leonard,Jean-Luc Veyrune,Guilhem Requirandet al. British Journal of Cancer, 2013, 109 (3), pp.676-85. ⟨10.1038/bjc.2013.392⟩ Article dans une revue inserm-00906782v1
Identification of pluripotent and adult stem cell genes unrelated to cell cycle and associated with poor prognosis in multiple myeloma. Alboukadel Kassambara,Dirk Hose,Jérôme Moreaux,Thierry Rème,Jennifer Torrentet al. PLoS ONE, 2012, 7 (7), pp.e42161. ⟨10.1371/journal.pone.0042161⟩ Article dans une revue inserm-00802686v1
Development of gene expression-based risk score in cytogenetically normal acute myeloid leukemia patients. Elias Bou Samra,Bernard Klein,Thérèse Commes,Jérôme Moreaux Oncotarget, 2012, 3 (8), pp.824-32 Article dans une revue inserm-00726665v1
Genes with a spike expression are clustered in chromosome (sub)bands and spike (sub)bands have a powerful prognostic value in patients with multiple myeloma. Alboukadel Kassambara,Dirk Hose,Jérôme Moreaux,Brian A. Walker,Alexei Protopopovet al. Haematologica, 2012, 97 (4), pp.622-30. ⟨10.3324/haematol.2011.046821⟩ Article dans une revue inserm-00727008v1
Gene expression-based risk score in diffuse large B-cell lymphoma. Caroline Bret,Bernard Klein,Jérôme Moreaux Oncotarget, 2012, 3 (12), pp.1700-10 Article dans une revue inserm-00802570v1
STEAP1 is overexpressed in cancers: A promising therapeutic target. Jérôme Moreaux,Alboukadel Kassambara,Dirk Hose,Bernard Klein Biochemical and Biophysical Research Communications, 2012, epub ahead of print. ⟨10.1016/j.bbrc.2012.10.123⟩ Article dans une revue inserm-00760262v1
Development of gene expression-based score to predict sensitivity of multiple myeloma cells to DNA methylation inhibitors. Jérôme Moreaux,Thierry Rème,Wim Leonard,Jean-Luc Veyrune,Guilhem Requirandet al. Molecular Cancer Therapeutics, 2012, 11 (12), pp.2685-92. ⟨10.1158/1535-7163.MCT-12-0721⟩ Article dans une revue inserm-00760269v1
Clinical and prognostic role of annexin A2 in multiple myeloma. Anja Seckinger,Tobias Meiβner,Jérôme Moreaux,Daniela Depeweg,Jens Hillengasset al. Blood, 2012, 120 (5), pp.1087-94. ⟨10.1182/blood-2012-03-415588⟩ Article dans une revue inserm-00726994v1
Residual malignant and normal plasma cells shortly after high dose melphalan and stem cell transplantation. Highlight of a putative therapeutic window in Multiple Myeloma? Anouk Caraux,Laure Vincent,Salahedine Bouhya,Philippe Quittet,Jérôme Moreauxet al. Oncotarget, 2012, 3 (11), pp.1335-47 Article dans une revue inserm-00802665v1
New prognostic markers, determined using gene expression analyses, reveal two distinct subtypes of chronic myelomonocytic leukaemia patients. Elias Bou Samra,Jérôme Moreaux,Fabienne Vacheret,Ken Mills,Florence Ruffléet al. British Journal of Haematology, 2012, 157 (3), pp.347-56. ⟨10.1111/j.1365-2141.2012.09069.x⟩ Article dans une revue inserm-00681007v1
SULFs in human neoplasia: implication as progression and prognosis factors. Caroline Bret,Jérôme Moreaux,Jean-François Schved,Dirk Hose,Bernard Klein Journal of Translational Medicine, 2011, 9 (1), pp.72. ⟨10.1186/1479-5876-9-72⟩ Article dans une revue inserm-00601153v1
Osteoclast-gene expression profiling reveals osteoclast-derived CCR2 chemokines promoting myeloma cell migration. Jérôme Moreaux,Dirk Hose,Alboukadel Kassambara,Thierry Rème,Philippe Moineet al. Blood, 2011, 117 (4), pp.1280-90. ⟨10.1182/blood-2010-04-279760⟩ Article dans une revue inserm-00906774v1
A high-risk signature for patients with multiple myeloma established from the molecular classification of human myeloma cell lines. Jérôme Moreaux,Bernard Klein,Régis Bataille,Géraldine Descamps,Sophie Maïgaet al. Haematologica, 2011, 96 (4), pp.574-82. ⟨10.3324/haematol.2010.033456⟩ Article dans une revue inserm-00550232v1
Growth factors in multiple myeloma: a comprehensive analysis of their expression in tumor cells and bone marrow environment using Affymetrix microarrays. Karène Mahtouk,Jérôme Moreaux,Dirk Hose,Thierry Rème,Tobias Meissneret al. BMC Cancer, 2010, 10 (1), pp.198. ⟨10.1186/1471-2407-10-198⟩ Article dans une revue inserm-00668220v1
MYEOV is a prognostic factor in multiple myeloma. Jérôme Moreaux,Dirk Hose,Amélie Bonnefond,Thierry Rème,Nicolas Robertet al. Experimental Hematology, 2010, 38 (12), pp.1189-1198.e3. ⟨10.1016/j.exphem.2010.09.002⟩ Article dans une revue inserm-00906769v1
Bone morphogenic protein 6: a member of a novel class of prognostic factors expressed by normal and malignant plasma cells inhibiting proliferation and angiogenesis. Anja Seckinger,Tobias Meissner,Jérôme Moreaux,Hartmut Goldschmidt,Gwenny M. Fuhleret al. Oncogene, 2009, 28 (44), pp.3866-79. ⟨10.1038/onc.2009.257⟩ Article dans une revue inserm-00437705v1
The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor. Anne Catherine Sprynski,Dirk Hose,Laurent Caillot,Thierry Rème,John D. Shaughnessy Jret al. Blood, 2009, 113 (19), pp.4614-4626. ⟨10.1182/blood-2008-07-170464⟩ Article dans une revue inserm-00367812v1
Embryonic stem cell markers expression in cancers. Matthieu Schoenhals,Alboukadel Kassambara,John De Vos,Dirk Hose,Jérôme Moreauxet al. Biochemical and Biophysical Research Communications, 2009, 383, pp.157-162. ⟨10.1016/j.bbrc.2009.02.156⟩ Article dans une revue inserm-00367054v1
Inhibition of Aurora-kinases for tailored risk adapted treatment of multiple myeloma. Dirk Hose,Thierry Rème,Tobias Meissner,Jérôme Moreaux,Anja Seckingeret al. Blood, 2009, 113 (18), pp.4331-4340. ⟨10.1182/blood-2008-09-178350⟩ Article dans une revue inserm-00368414v1
APRIL is overexpressed in cancer: link with tumor progression. Jérôme Moreaux,Jean-Luc Veyrune,John de Vos,Bernard Klein BMC Cancer, 2009, 9 (1), pp.83. ⟨10.1186/1471-2407-9-83⟩ Article dans une revue inserm-00369505v1
Induction of angiogenesis by normal and malignant plasma cells. Dirk Hose,Jérôme Moreaux,Tobias Meissner,Anja Seckinger,Hartmut Goldschmidtet al. Blood, 2009, 114, pp.128-143. ⟨10.1182/blood-2008-10-184226⟩ Article dans une revue inserm-00401390v1
APRIL and TACI interact with syndecan-1 on the surface of multiple myeloma cells to form an essential survival loop. Jérôme Moreaux,Anne-Catherine Sprynski,Stacey R. Dillon,Karène Mahtouk,Michel Jourdanet al. European Journal of Haematology, 2009, 83 (2), pp.119-29. ⟨10.1111/j.1600-0609.2009.01262.x⟩ Article dans une revue inserm-00397249v1
CD200: a putative therapeutic target in cancer. Jérôme Moreaux,Jean-Luc Veyrune,Thierry Rème,John de Vos,Bernard Klein Biochemical and Biophysical Research Communications, 2008, 366 (1), pp.117-22. ⟨10.1016/j.bbrc.2007.11.103⟩ Article dans une revue inserm-00195258v1
MMSET is overexpressed in cancers: Link with tumor aggressiveness. Alboukadel Kassambara,Bernard Klein,Jérôme Moreaux Biochemical and Biophysical Research Communications, 2008, 379, pp.840-845. ⟨10.1016/j.bbrc.2008.12.093⟩ Article dans une revue inserm-00356253v1
Targeting NF-kappaB pathway with an IKK2 inhibitor induces inhibition of multiple myeloma cell growth. Michel Jourdan,Jérôme Moreaux,John De Vos,Dirk Hose,Karène Mahtouket al. British Journal of Haematology, 2007, 138 (2), pp.160-8. ⟨10.1111/j.1365-2141.2007.06629.x⟩ Article dans une revue inserm-00160647v1
Input of DNA microarrays to identify novel mechanisms in multiple myeloma biology and therapeutic applications. Karène Mahtouk,Dirk Hose,John de Vos,Jérôme Moreaux,Michel Jourdanet al. Clinical Cancer Research, 2007, 13 (24), pp.7289-95. ⟨10.1158/1078-0432.CCR-07-1758⟩ Article dans une revue inserm-00270566v1
TACI expression is associated with a mature bone marrow plasma cell signature and C-MAF overexpression in human myeloma cell lines. Jérôme Moreaux,Dirk Hose,Michel Jourdan,Thierry Rème,Michael Hundemeret al. Haematologica, 2007, 92 (6), pp.803-11 Article dans une revue inserm-00162002v1
Heparan sulphate proteoglycans are essential for the myeloma cell growth activity of EGF-family ligands in multiple myeloma. Karène Mahtouk,Friedrich W. Cremer,Thierry Rème,Michel Jourdan,Marion Baudardet al. Oncogene, 2006, 25 (54), pp.7180-91. ⟨10.1038/sj.onc.1209699⟩ Article dans une revue inserm-00128880v1
Microarray-based understanding of normal and malignant plasma cells. John de Vos,Dirk Hose,Thierry Rème,Karin Tarte,Jérôme Moreauxet al. Immunological Reviews, 2006, 210, pp.86-104. ⟨10.1111/j.0105-2896.2006.00362.x⟩ Article dans une revue inserm-00149827v1
CD200 is a new prognostic factor in multiple myeloma. Jérôme Moreaux,Dirk Hose,Thierry Rème,Eric Jourdan,Michael Hundemeret al. Blood, 2006, 108 (13), pp.4194-7. ⟨10.1182/blood-2006-06-029355⟩ Article dans une revue inserm-00130595v1
Expression of EGF-family receptors and amphiregulin in multiple myeloma. Amphiregulin is a growth factor for myeloma cells. Karène Mahtouk,Dirk Hose,Thierry Rème,John de Vos,Michel Jourdanet al. Oncogene, 2005, 24 (21), pp.3512-24. ⟨10.1038/sj.onc.1208536⟩ Article dans une revue inserm-00130206v1
The level of TACI gene expression in myeloma cells is associated with a signature of microenvironment dependence versus a plasmablastic signature. Jérôme Moreaux,Friedrich W. Cremer,Thierry Rème,Marc Raab,Karene Mahtouket al. Blood, 2005, 106 (3), pp.1021-30. ⟨10.1182/blood-2004-11-4512⟩ Article dans une revue inserm-00129406v1
BAFF and APRIL protect myeloma cells from apoptosis induced by interleukin 6 deprivation and dexamethasone. Jérôme Moreaux,Eric Legouffe,Eric Jourdan,Philippe Quittet,Thierry Rèmeet al. Blood, 2004, 103 (8), pp.3148-57. ⟨10.1182/blood-2003-06-1984⟩ Article dans une revue inserm-00129502v1
Survival and proliferation factors of normal and malignant plasma cells. Bernard Klein,Karin Tarte,Michel Jourdan,Karene Mathouk,Jérôme Moreauxet al. International Journal of Hematology, 2003, 78 (2), pp.106-13 Article dans une revue inserm-00130900v1

Communication dans un congrès (3)

Abstract C047: Unraveling proteotoxic and oxidative stress - driven adaptations in multiple myeloma Despoina D. Gianniou,Eirini Gkogkou,Paraskevi Karousi,Julie Courraud,Jérôme Moreauxet al. International Conference on Molecular Targets and Cancer Therapeutics, American Association for Cancer Research; National Cancer Institute; European Organisation for Research and Treatment of Cancer, Oct 2025, Boston (Massachusetts), United States. ⟨10.1158/1535-7163.TARG-25-C047⟩ Communication dans un congrès hal-05473990v1
Integrative Single-Cell RNA-Seq and Single-Cell ATAC-Seq Analysis of Human Plasma Cell Differentiation Elina Alaterre,Sara Ovejero,Marion Espéli,Thierry Fest,Michel Cognéet al. 65th Annual Meeting of the American Society of Hematology (ASH 2023), American Society of Hematology (ASH), Dec 2023, San Diego, United States. ⟨10.1182/blood-2023-181507⟩ Communication dans un congrès hal-04513440v1
Une collection unique de cellules viables humaines cryopréservées de patients atteints de lymphomes, une initiative pour accélérer l'innovation et son transfert dans le domaine du lymphome. E Mollaret,E Gomez,B Nadel,L Baseggio,E Blascoet al. SFH, 2020, Paris, France Communication dans un congrès inserm-04827406v1

Poster de conférence (16)

Alternative splicing complexity results in a very diverse repertoire of circular RNAs in multiple myeloma, as revealed by nanopore sequencing Maria Papatsirou,Evangelos Terpos,Jérôme Moreaux,Andreas Scorilas,Christos Kontos 49th FEBS Congress, Jul 2025, Istanbul, Turkey. , FEBS OPEN BIO, 15 (Supplement 2), pp.132 / P-16-006, 2025, ⟨10.1002/2211-5463.70071⟩ Poster de conférence hal-05529890v1
Circular RNA Profiling Using High-Accuracy Long-Read Nanopore Sequencing of Multiple Myeloma Cell Lines Reveals the Wide Diversity of the Circular Transcriptome Maria Papatsirou,Christos Kontos,Ioannis Ntanasis-Stathopoulos,Christina Sotiropoulou,Christine-Ivy Liacoset al. 66th American Society of Hematology Annual Meeting and Exposition (ASH 2024), Dec 2024, San Diego (CA), United States. , Blood, 144 (Supplement 1), pp.3285-3285, 2024, ⟨10.1182/blood-2024-206812⟩ Poster de conférence hal-05528579v1
Epigenetic Modifiers MMSET and EZH2 Physically Interact and Cooperate to Support Multiple Myeloma Pathophysiology Emmanuel Varlet,Elina Alaterre,Morgane Thomas,Hugues de Boussac,Laure Vincentet al. 65th ASH Annual Meeting (ASH 2023), Dec 2023, San Diego (CA), United States. Elsevier, Blood, 142 (Supplement 1), pp.1964-1965, 2023, The 65th ASH Annual Meeting Abstracts. ⟨10.1182/blood-2023-181018⟩ Poster de conférence hal-05479158v1
Targeting iron homeostasis in combination with IMiDs as a therapeutic strategy in multiple myeloma Sara Ovejero,Julie Devin,Tatiana Cañeque,Laura Henry,Laura Alibertet al. 20th International Myeloma Society Annual Meeting (IMS 2023), Sep 2023, Athène, Greece. , Clinical Lymphoma, Myeloma and Leukemia, 23 (Suppl. 2), pp.S149 / P207, 2023, The Abstract from International Myeloma Society 20th Annual Meeting and Exposition Poster de conférence hal-05485234v1
Translation Inhibition through eIF4A1 Targeting in Multiple Myeloma Is a Promising Therapeutic Strategy Laure Dutrieux,Elle Loughran,Armelle Choquet,Hélène Herault,Antoine Guilleminet al. ASH 2023 - 65th ASH Annual Meeting, Dec 2023, San Diego, CA, United States. Elsevier, Blood, 142 (Supplement 1), pp.1924-1925, 2023, The 65th ASH Annual Meeting Abstracts. ⟨10.1182/blood-2023-184749⟩ Poster de conférence hal-05474729v1
Early Progressions of Undetermined Significance (EPUS) in the Month Following CAR-T Cells for B-Cell NHL Is Mainly Related to Pseudoprogression Benoît Tisserand,Caroline Bret,Yassine Al Tabaa,Sylvain Lamure,Xavier Ayrignacet al. 65th ASH Annual Meeting (ASH 2023), Dec 2023, San Diego (CA), United States. Elsevier, Blood, 142 (Supplement 1), pp.3124-3125, 2023, The 65th ASH Annual Meeting Abstracts. ⟨10.1182/blood-2023-185520⟩ Poster de conférence hal-05474613v1
Exploiting transcription-replication conflicts as a novel therapeutic intervention in multiple myeloma Laure Dutrieux,Antoine Guillemin,Yea-Lih Lin,Malik Lutzmann,Guilhem Requirandet al. 20th International Myeloma Society Annual Meeting (IMS 2023), Sep 2023, Athène, Greece. , Clinical Lymphoma, Myeloma and Leukemia, 23 (Suppl. 2), pp.S139 / P188, 2023, The Abstract from International Myeloma Society 20th Annual Meeting and Exposition Poster de conférence hal-05485282v1
Lipid-Mediated Modulation of DNA Damage Signaling As a Prognostic and Therapeutic Strategy Against Multiple Myeloma Elvira Garcia de Paco,Caroline Soulet,Guilhem Requirand,Nicolas Robert,Guillaume Cartronet al. 65th ASH Annual Meeting (ASH 2023), Dec 2023, San Diego (CA), United States. Elsevier, Blood, 142 (Suppl. 1), pp.3322-3322, 2023, The 65th ASH Annual Meeting Abstracts. ⟨10.1182/blood-2023-181039⟩ Poster de conférence hal-05329546v1
Characterization of a New Metabolic Score Correlated with CD38 Cell-Surface Expression and Response to Daratumumab Treatment in Multiple Myeloma Alizée Steer,Elina Alaterre,Djamila Chamlal,Emmanuel Varlet,Amélie Machuraet al. 65th ASH Annual Meeting (ASH 2023), Dec 2023, San Diego (CA), United States. Elsevier, Blood, 142 (Supplement 1), pp.1949-1950, 2023, The 65th ASH Annual Meeting Abstracts. ⟨10.1182/blood-2023-180877⟩ Poster de conférence hal-05474734v1
Integrative Multi-Omics Analysis of Tumor-Immune Microenvironment in Multiple Myeloma: Novel Insights and Therapeutic Implications Elina Alaterre,Nicolas Robert,Guilhem Requirand,Amélie Machura,Hugues de Boussacet al. 65th ASH Annual Meeting (ASH 2023), Dec 2023, San Diego (CA), United States. Elsevier, Blood, 142 (Supplement 1), pp.4743-4743, 2023, The 65th ASH Annual Meeting Abstracts. ⟨10.1182/blood-2023-181767⟩ Poster de conférence hal-05470292v1
Development of a Robust BH3 Profiling Toolkit for Precision Medicine in Hematologic Malignancies Valentin Jacquier,Antoine Guillemin,Sara Ovejero,Guilhem Requirand,Ouissem Karmous-Gadachaet al. 64th American Society of Hematology Annual Meeting and Exposition (ASH 2022), Dec 2022, Nouvelle Orléans (LA), United States. , Blood, 140 (Supplement 1), pp.10727-10728, 2022, ⟨10.1182/blood-2022-163207⟩ Poster de conférence hal-05518486v1
Ironomycin induces mantle cell lymphoma cell death by targeting iron metabolism addiction Sara Ovejero,Laura Alibert,Julie Devin,Tatiana Cañeque,Ouissem Karmous Gadachaet al. 64th American Society of Hematology Annual Meeting and Exposition (ASH 2022), Dec 2022, Nouvelle Orléans (LA), United States. , Blood, 140 (Suppl. 1), pp.6439-6440, 2022, ⟨10.1182/blood-2022-164644⟩ Poster de conférence hal-05495200v1
Targeting iron homeostasis as a therapeutic strategy in multiple myeloma Sara Ovejero,Julie Devin,Tatiana Cañeque,Laura Alibert,Guilhem Requirandet al. 64th American Society of Hematology Annual Meeting and Exposition (ASH 2022), Dec 2022, Nouvelle Orléans (LA), United States. , Blood, 140 (Suppl. 1), pp.9980-9981, 2022, ⟨10.1182/blood-2022-163252⟩ Poster de conférence hal-05495235v1
EZH2 Targeting Induces CD38 Upregulation and Response to Anti-CD38 Antibodies in Multiple Myeloma Djamila Chemlal,Emmanuel Varlet,Amélie Machura,Guilhem Requirand,Nicolas Robertet al. 64th American Society of Hematology Annual Meeting and Exposition (ASH 2022), Dec 2022, Nouvelle Orléans (LA), United States. , Blood, 140 (Supplement 1), pp.4220-4221, 2022, ⟨10.1182/blood-2022-163261⟩ Poster de conférence hal-05518542v1
Genomic Characterization of in Vitro Acquired-Resistance to Proteasome Inhibitors Hugues De Boussac,Alboukadel Kassambara,Amélie Machura,Djamila Chemlal,Claire Gourzoneset al. 63rd American Society of Hematology Annual Meeting and Exposition (ASH 2021), Dec 2021, Atlanta (GA), United States. , Blood, 138 (Suppl. 1), pp.2651, 2021, Annual Meeting Abstracts. ⟨10.1182/blood-2021-148584⟩ Poster de conférence hal-05520417v1
Exploiting transcription-replication conflicts as a novel therapeutic intervention in multiple myeloma Laure Dutrieux,Yea-Lih Lin,Malik Lutzmann,Guilhem Requirand,Nicolas Robertet al. 63rd American Society of Hematology Annual Meeting and Exposition (ASH 2021), Dec 2021, Atlanta (GA), United States. , Blood, 138 (Suppl. 1), pp.1582, 2021, Annual Meeting Abstracts. ⟨10.1182/blood-2021-151530⟩ Poster de conférence hal-05520336v1

Pré-publication, Document de travail (5)

Single-Nuclei Analysis of the Unfolded Protein Response (SNUPR): A Novel Method revealing bortezomib resistance mechanisms in Multiple Myeloma Julien Gigan,Paulina Garcia-Gonzalez,Lou Galliot,Alexandre Reynaud,Yoan Ghaffaret al. 2024 Pré-publication, Document de travail (preprint/prepublication) hal-04791295v1
“Single-Nuclei Analysis of the Unfolded Protein Response (SNUPR) reveals bortezomib resistance mechanisms in Multiple Myeloma” Julien P Gigan,Paulina Garcia-Gonzalez,Lou Galliot,Alexandre Reynaud,Yoan Ghaffaret al. 2025 Pré-publication, Document de travail hal-05348771v1
Regulation of oncogene-induced senescence by the MRE11 and TREX1 nucleases Hervé Técher,Diyavarshini Gopaul,Jonathan Heuzé,Baptiste Leray,Audrey Vernetet al. 2023 Pré-publication, Document de travail hal-04315770v1
Transient loss of Polycomb components induces an epigenetic cancer fate Victoria Parreno,Vincent Loubiere,Bernd Schuettengruber,Maksim Erokhin,Balázs Győrffyet al. 2023 Pré-publication, Document de travail hal-04252107v1
Targeting the methyltransferase SETD8 impairs tumor cell survival and overcomes drug resistance independently of p53 status in multiple myeloma Eric Julien,Laurie Herviou,Fanny Izard,Ouissem Karmous-Gadacha,Claire Gourzoneset al. 2020 Pré-publication, Document de travail hal-02997556v1

Thèse (1)

ROLE DES MEMBRES DE LA FAMILLE BAFF/APRIL DANS LE MYELOME MULTIPLE : IMPLICATIONS PHYSIOPATHOLOGIQUES ET INTERET THERAPEUTIQUE Jérôme Moreaux Immunologie. Université Montpellier I, 2006. Français. ⟨NNT : ⟩ Thèse tel-00130594v1