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The cyclic imine core common to the marine macrocyclic toxins is sufficient to dictate nicotinic acetylcholine receptor antagonism
Yves Bourne
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Gerlind Sulzenbacher
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Laurent Chabaud
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Rómulo Aráoz
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Zoran Radić
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Article dans une revue
hal-04542228v1
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Stable Convergent Polyneuronal Innervation and Altered Synapse Elimination in Orbicularis oculi Muscles from Patients with Blepharospasm Responding Poorly to Recurrent Botulinum Type-A Neurotoxin Injections
Brigitte Girard
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Aurélie Couesnon
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Emmanuelle Girard
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Jordi Molgó
Article dans une revue
hal-04868727v1
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Acute effects of brevetoxin-3 administered via oral gavage to mice
Peggy Barbe
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Jordi Molgó
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Article dans une revue
hal-04428300v1
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Editorial: Pharmacological Aspects of Ligand-Gated Ion Channels as Targets of Natural and Synthetic Agents
César Mattei
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Hélène Tricoire-Leignel
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Christian Legros
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Richard Lewis
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Jordi Molgó
Article dans une revue
hal-03635549v1
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A Ca 2+ -dependent mechanism boosting glycolysis and OXPHOS by activating aralar-malate-aspartate shuttle, upon neuronal stimulation
Irene Pérez-Liébana
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Inés Juaristi
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Luis González-Moreno
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Article dans une revue
cea-04460138v1
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Gambierol blocks a K(+) current fraction without affecting catecholamine release in rat fetal adrenomedullary cultured chromaffin cells
Evelyne Benoit
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Sébastien Schlumberger
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Jordi Molgó
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Makoto Sasaki
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Haruhiko Fuwa
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Article dans une revue
hal-03629624v1
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Guidance Level for Brevetoxins in French Shellfish
Nathalie Arnich
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Eric Abadie
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Zouher Amzil
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Marie-Yasmine Dechraoui Bottein
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Article dans une revue
anses-03350437v1
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Inhibition of InsP3R with Xestospongin B reduces mitochondrial respiration and induces selective cell death in T cell acute lymphoblastic leukemia cells
Pablo Cruz
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Ulises Ahumada-Castro
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Galdo Bustos
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Jordi Molgo
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Daniela Sauma
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Article dans une revue
hal-03630856v1
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First evidence that emerging pinnatoxin-G, a contaminant of shellfish, reaches the brain and crosses the placental barrier
Denis Servent
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Carole Malgorn
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Mylène Bernes
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Sophie Gil
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Christelle Simasotchi
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Article dans une revue
hal-03285879v1
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Backbone Cyclization Turns a Venom Peptide into a Stable and Equipotent Ligand at Both Muscle and Neuronal Nicotinic Receptors
Julien Giribaldi
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Yves Haufe
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Edward Evans
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Muriel Amar
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Anna Durner
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Article dans une revue
hal-02995265v1
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Cyclic imine toxins survey in coastal european shellfish samples: Bioaccumulation and mode of action of 28-O-palmitoyl ester of pinnatoxin-G. first report of portimine-A bioaccumulation
Rómulo Aráoz
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Paul Barnes
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Véronique Séchet
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Muriel Delepierre
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Sophie Zinn-Justin
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Article dans une revue
hal-03001984v1
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Purification, Toxicity and Functional Characterization of a New Proteinaceous Mussel Biotoxin from Bizerte Lagoon
Riadh Marrouchi
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Evelyne Benoit
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Sébastien Schlumberger
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Zeineb Marzougui
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Jean-Pierre Le Caër
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Article dans une revue
hal-02913966v1
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Cancer cells with defective oxidative phosphorylation require endoplasmic reticulum–to–mitochondria Ca 2+ transfer for survival
Cesar Cardenas
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Alenka Lovy
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Eduardo Silva-Pavez
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Felix Urra
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Craig Mizzoni
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Article dans une revue
hal-04461478v1
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Concerted Action of AMPK and Sirtuin-1 Induces Mitochondrial Fragmentation Upon Inhibition of Ca2+ Transfer to Mitochondria
Alenka Lovy
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Galdo Bustos
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Paula Farias
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Christian Gonzalez-Billault
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Article dans une revue
hal-04460599v1
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Gambierol Potently Increases Evoked Quantal Transmitter Release and Reverses Pre- and Post-Synaptic Blockade at Vertebrate Neuromuscular Junctions
Jordi Molgó
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Sébastien Schlumberger
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Makoto Sasaki
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Haruhiko Fuwa
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Carmen M. Louzao
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Article dans une revue
hal-02324830v1
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Pinnatoxins, an emergent class of marine toxins interacting with nAChRs. Pharmacological characterization, biodistribution and musculo-skeletal effect of these neurotoxic agents
Denis Servent
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Sophie Creuzet
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Carole Malgorn
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Vincent Dive
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Armen Zakarian
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Article dans une revue
hal-02912939v1
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Health risk assessment related to pinnatoxins in French shellfish
Nathalie Arnich
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Eric Abadie
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Nicolas Delcourt
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Valérie Fessard
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Jean-Marc Fremy
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Article dans une revue
anses-02861821v1
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Pinnatoxins’ Deleterious Effects on Cholinergic Networks: From Experimental Models to Human Health
Nicolas Delcourt
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Emmeline Lagrange
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Eric Abadie
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Valérie Fessard
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Jean-Marc Frémy
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Article dans une revue
hal-04215114v1
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Synthetic Pinnatoxins A and G Reversibly Block Mouse Skeletal Neuromuscular Transmission In Vivo and In Vitro
Evelyne Benoit
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Aurélie Couesnon
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Jiri Lindovsky
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Bogdan Iorga
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Rómulo Aráoz
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Article dans une revue
hal-02194723v1
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Aptamer efficacies for in vitro and in vivo modulation of $\alpha$C-conotoxin PrXA pharmacology
Germain Sotoing Taïwe
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Jérôme Montnach
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Sébastien Nicolas
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Stephan de Waard
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Emmanuelle Fiore
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Article dans une revue
cea-02571967v1
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Pinnatoxins’ Deleterious Effects on Cholinergic Networks: From Experimental Models to Human Health
Nicolas Delcourt
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Emmeline Lagrange
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Eric Abadie
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Valérie Fessard
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Jean-Marc Frémy
et al.
Article dans une revue
anses-02346887v1
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Inositol trisphosphate receptor-mediated Ca2+ signalling stimulates mitochondrial function and gene expression in core myopathy patients
Matteo Suman
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Jenny Sharpe
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Robert Bentham
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Vassilios Kotiadis
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Michela Menegollo
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Article dans une revue
hal-04462217v1
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The cyclic imine Prorocentrolide-A obtained from cultured Japanese Prorocentrum lima dinoflagellates target muscle- and neuronal-type nicotinic acetylcholine receptors
Muriel Amar
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Rómulo Aráoz
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Bogdan Iorga
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Takeshi Yasumoto
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Denis Servent
et al.
Article dans une revue
istex
hal-03164771v1
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Cyclic imine toxins from dinoflagellates: a growing family of potent antagonists of the nicotinic acetylcholine receptors
Jordi Molgó
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Pascale Marchot
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Rómulo Aráoz
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Evelyne Benoit
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Bogdan I Iorga
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Article dans une revue
hal-01661784v1
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Efficient functional neutralization of lethal peptide toxins in vivo by oligonucleotides
Tarek Mohamed Abd El-Aziz
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Corinne Ravelet
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Jordi Molgó
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Emmanuelle Fiore
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Simon Pale
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Article dans une revue
hal-01639599v1
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Ostreolysin A/Pleurotolysin B and Equinatoxins: Structure, Function and Pathophysiological Effects of These Pore-Forming Proteins.
Robert Frangež
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Dušan Šuput
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Jordi Molgó
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Evelyne Benoit
Article dans une revue
hal-01572247v1
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The Dinoflagellate Toxin 20-Methyl Spirolide-G Potently Blocks Skeletal Muscle and Neuronal Nicotinic Acetylcholine Receptors.
Aurélie Couesnon
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Rómulo Aráoz
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Bogdan I Iorga
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Evelyne Benoit
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Morgane Reynaud
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Article dans une revue
hal-01443823v1
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Translocation and dissemination to target neurons of botulinum neurotoxin type B in the mouse intestinal wall
Chloé Connan
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Carolina Varela-Chavez
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Christelle Mazuet
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Jordi Molgó
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Michel Haustant
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Article dans une revue
pasteur-01780625v1
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Selectivity of Spiroimine Phycotoxins Toward Nicotinic Acetylcholine Receptors
Bogdan Iorga
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Rómulo Aráoz
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Evelyne Benoit
,
Jordi Molgó
Article dans une revue
hal-03163853v1
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Sympathetic innervation controls homeostasis of neuromuscular junctions in health and disease.
Muzamil Majid Khan
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Danilo Lustrino
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Willian A Silveira
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Franziska Wild
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Tatjana Straka
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Proceedings of the National Academy of Sciences of the United States of America, 2016, 113 (3), pp.746-50. ⟨10.1073/pnas.1524272113⟩
Article dans une revue
hal-01306149v1
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Neuromuscular junction immaturity and muscle atrophy are hallmarks of the ColQ-deficient mouse, a model of congenital myasthenic syndrome with acetylcholinesterase deficiency
Séverine M. Sigoillot
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Francine Bourgeois
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Jennifer Karmouch
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Jordi Molgó
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Alexandre Dobbertin
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Article dans une revue
hal-01664699v1
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Editorial : Special Issue on "Toxins: New targets and new functions".
Evelyne Benoit
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Julien Barbier
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Michel R Popoff
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Grazyna Faure
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Jordi Molgó
et al.
Article dans une revue
hal-01306142v1
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MuSK frizzled-like domain is critical for mammalian neuromuscular junction formation and maintenance.
Julien Messéant
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Alexandre Dobbertin
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Emmanuelle Girard
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Perrine Delers
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Marin Manuel
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Article dans une revue
hal-01165625v1
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Multi-target directed ligands: Electrophysiological characterization of an anticholinesterase inhibitor coupled to an agonist of α7 nicotinic acetylcholine receptor
Rómulo Aráoz
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Monika Bouet
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Manuela Bartolini
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Nicolas Coquelle
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Jacques-Philippe Colletier
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Article dans une revue
istex
hal-02329901v1
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Marine Macrocyclic Imines, Pinnatoxins A and G: Structural Determinants and Functional Properties to Distinguish Neuronal α7 from Muscle α12βγδ nAChRs.
Yves Bourne
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Gerlind Sulzenbacher
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Zoran Radić
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Rómulo Aráoz
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Morgane Reynaud
et al.
Article dans une revue
hal-01178822v1
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Endoplasmic reticulum Ca(2+) content decrease by PKA-dependent hyperphosphorylation of type 1 IP3 receptor contributes to prostate cancer cell resistance to androgen deprivation.
Benoît Boutin
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Nicolas Tajeddine
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Giovanni Monaco
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Jordi Molgó
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Didier Vertommen
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Article dans une revue
hal-01165614v1
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The neurotoxic effect of 13, 19-didesmethyl and 13-desmethyl spirolide C phycotoxins is mainly mediated by nicotinic rather than muscarinic acetylcholine receptors.
Rómulo Aráoz
,
Gilles Ouanounou
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Bogdan I Iorga
,
Amélie Goudet
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Doria Alili
et al.
Article dans une revue
hal-01165573v1
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Corrigenda: MCUR1 is an essential component of mitochondrial Ca(2+) uptake that regulates cellular metabolism.
Karthik Mallilankaraman
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César Cárdenas
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Patrick J Doonan
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Harish C Chandramoorthy
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Krishna M Irrinki
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Article dans une revue
hal-01178820v1
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Synthesis and biology of cyclic imine toxins, an emerging class of potent, globally distributed marine toxins.
Craig E Stivala
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Evelyne Benoit
,
Rómulo Aráoz
,
Denis Servent
,
Alexei Novikov
et al.
Article dans une revue
(article de synthèse)
hal-01178830v1
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Ryanodine and inositol triphosphate receptors modulate facilitation and tetanic depression at the frog neuromuscular junction.
Priscila E Silveira
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Ricardo F Lima
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Jennifer D S Guimarães
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Jordi Molgó
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Ligia A Naves
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Article dans une revue
istex
hal-01178827v1
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Detection of anatoxin-a and three analogs in Anabaena spp. cultures: new fluorescence polarization assay and toxin profile by LC-MS/MS.
Jon A Sanchez
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Paz Otero
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Amparo Alfonso
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Vitor Ramos
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Vitor Vasconcelos
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Article dans une revue
hal-01178842v1
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Bcl-2 binds to and inhibits ryanodine receptors.
Tim Vervliet
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Elke Decrock
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Jordi Molgó
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Vincenzo Sorrentino
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Ludwig Missiaen
et al.
Article dans une revue
hal-01178836v1
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Characterization of a novel Conus bandanus conopeptide belonging to the M-superfamily containing bromotryptophan.
Bao Nguyen
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Jean-Pierre Le Caer
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Gilles Mourier
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Robert Thai
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Hung Lamthanh
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Article dans une revue
hal-01020530v1
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Involvement of both sodium influx and potassium efflux in ciguatoxin-induced nodal swelling of frog myelinated axons.
César Mattei
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Jordi Molgó
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Evelyne Benoit
Article dans une revue
istex
hal-01178834v1
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Isolation, purification and functional characterization of alpha-BnIA from Conus bandanus venom.
Bao Nguyen
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Jean-Pierre Le Caer
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Romulo Aráoz
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Robert Thai
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Hung Lamthanh
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Toxicon, 2014, 91, pp.1551-63
Article dans une revue
hal-01112222v1
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Editorial : Special Issue on "freshwater and marine toxins".
Evelyne Benoit
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César Mattei
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Julien Barbier
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Pascale Marchot
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Jordi Molgó
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Article dans une revue
istex
hal-01165542v1
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Conformational flexibility of cyclic imine phycotoxins revealed by long-timescale molecular dynamics simulations
Romulo Aráoz
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Evelyne Benoit
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Jordi Molgó
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Bogdan Iorga
Article dans une revue
istex
hal-03161678v1
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Colorimetric microtiter plate receptor-binding assay for the detection of freshwater and marine neurotoxins targeting the nicotinic acetylcholine receptors.
Fernando Rubio
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Lisa Kamp
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Justin Carpino
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Erin Faltin
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Keith Loftin
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Article dans une revue
istex
hal-01165541v1
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Toxicity of the synthetic polymeric 3-alkylpyridinium salt (APS3) is due to specific block of nicotinic acetylcholine receptors.
Marjana Grandič
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Rómulo Aráoz
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Jordi Molgó
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Tom Turk
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Kristina Sepčić
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Article dans une revue
istex
hal-00781185v1
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Detection and toxicity of C17-sphinganine analogue mycotoxin contaminating mussels from Tunisia
R. Marrouchi
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Evelyne Benoit
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Jordi Molgó
,
Riadh Kharrat
Article dans une revue
istex
hal-01705417v1
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Pinnatoxin G is responsible for atypical toxicity in mussels (Mytilus galloprovincialis) and clams (Venerupis decussata) from Ingril, a French Mediterranean lagoon.
Philipp Hess
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Eric Abadie
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Fabienne Hervé
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Tom Berteaux
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Véronique Séchet
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Article dans une revue
hal-00919909v1
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Development of a Solid-Phase Receptor-Based Assay for the Detection of Cyclic Imines Using a Microsphere-Flow Cytometry System.
Laura Pérez Rodríguez
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Natalia Vilariño
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Jordi Molgó
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Rómulo Aráoz
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M. Carmen Louzao
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Article dans une revue
hal-00781176v1
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High accuracy mass spectrometry comparison of Conus bandanus and Conus marmoreus venoms from the South Central Coast of Vietnam.
Bao Nguyen
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Jordi Molgó
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Hung Lamthanh
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Evelyne Benoit
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Thi An Khuc
et al.
Article dans une revue
istex
hal-00912394v1
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IP3R2 levels dictate the apoptotic sensitivity of diffuse large B-cell lymphoma cells to an IP3R-derived peptide targeting the BH4 domain of Bcl-2.
H. Akl
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G. Monaco
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R. La Rovere
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K. Welkenhuyzen
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S. Kiviluoto
et al.
Article dans une revue
hal-00850296v1
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Editorial : Special issue on "toxins: from threats to benefits".
Marie-France Martin-Eauclaire
,
Evelyne Benoit
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Pascale Marchot
,
Julien Barbier
,
Jordi Molgó
et al.
Article dans une revue
hal-00919888v1
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CLIPR-59: a protein essential for neuromuscular junction stability during mouse late embryonic development.
Aurélie Couesnon
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Nicolas Offner
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Véronique Bernard
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Nathalie Chaverot
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Stéphanie Backer
et al.
Article dans une revue
hal-00850320v1
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Identification and functional characterization of a novel α-conotoxin (EIIA) from Conus ermineus.
Loïc Quinton
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Denis Servent
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Emmanuelle Girard
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Jordi Molgó
,
Jean-Pierre Le Caer
et al.
Article dans une revue
istex
hal-00850305v1
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An overview of cellular and in vivo actions of equinatoxins
Dusan Suput
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Jordi Molgó
,
Robert Frangež
,
Evelyne Benoit
Article dans une revue
istex
hal-01704379v1
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Toxic c17-sphinganine analogue mycotoxin, contaminating tunisian mussels, causes flaccid paralysis in rodents.
Riadh Marrouchi
,
Evelyne Benoit
,
Jean-Pierre Le Caer
,
Nawel Bedjaoui
,
Hafedh Belghith
et al.
Article dans une revue
hal-00911028v1
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A roadmap for hazard monitoring and risk assessment of marine biotoxins on the basis of chemical and biological test systems.
Mardas Daneshian
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Luis M Botana
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Marie-Yasmine Dechraoui Bottein
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Gemma Buckland
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Mònica Campàs
et al.
Article dans une revue
hal-00914469v1
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Analysis of the action of gymnodimine-A and 13-desmethyl spirolide C on the mouse neuromuscular system in vivo.
Riadh Marrouchi
,
Guillaume Rome
,
Riadh Kharrat
,
Jordi Molgó
,
Evelyne Benoit
Article dans une revue
pasteur-00859280v1
|
|
|
High-throughput receptor-based assay for the detection of spirolides by chemiluminescence.
Laura P Rodríguez
,
Natalia Vilariño
,
Jordi Molgó
,
Rómulo Aráoz
,
Luis M Botana
Article dans une revue
istex
hal-00919891v1
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Botulinum Neurotoxin Type A is Internalized and Translocated from Small Synaptic Vesicles at the Neuromuscular Junction.
Cesare Colasante
,
Ornella Rossetto
,
Laura Morbiato
,
Marco Pirazzini
,
Jordi Molgó
et al.
Article dans une revue
istex
hal-00850323v1
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Early presynaptic and postsynaptic calcium signaling abnormalities mask underlying synaptic depression in presymptomatic Alzheimer's disease mice.
Shreaya Chakroborty
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Joyce Kim
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Corinne Schneider
,
Christopher Jacobson
,
Jordi Molgó
et al.
Article dans une revue
hal-00723212v1
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The stretch-activated channel blocker gd(3+) reduces palytoxin toxicity in primary cultures of skeletal muscle cells.
Giorgia del Favero
,
Chiara Florio
,
Barbara Codan
,
Silvio Sosa
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Mark Poli
et al.
Article dans une revue
hal-00738551v1
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|
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A novel µ-conopeptide, CnIIIC, exerts potent and preferential inhibition of NaV1.2/1.4 channels and blocks neuronal nicotinic acetylcholine receptors
Philippe Favreau
,
Evelyne Benoit
,
Henry G Hocking
,
Ludovic Carlier
,
Dieter d'Hoedt
et al.
Article dans une revue
hal-00683620v1
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Stability of cyclic imine toxins: interconversion of pinnatoxin amino ketone and pinnatoxin a in aqueous media.
Jeffrey J Jackson
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Craig E Stivala
,
Bogdan I Iorga
,
Jordi Molgó
,
Armen Zakarian
Article dans une revue
hal-00756265v1
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MICU1 is an essential gatekeeper for MCU-mediated mitochondrial Ca(2+) uptake that regulates cell survival.
Karthik Mallilankaraman
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Patrick Doonan
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César Cárdenas
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Harish C Chandramoorthy
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Marioly Müller
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Article dans une revue
hal-00781191v1
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MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism.
Karthik Mallilankaraman
,
César Cárdenas
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Patrick J Doonan
,
Harish C Chandramoorthy
,
Krishna M Irrinki
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Article dans une revue
hal-00781179v1
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|
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The non-competitive acetylcholinesterase inhibitor APS12-2 is a potent antagonist of skeletal muscle nicotinic acetylcholine receptors.
Marjana Grandič
,
Rómulo Aráoz
,
Jordi Molgó
,
Tom Turk
,
Kristina Sepčić
et al.
Article dans une revue
istex
hal-00781193v1
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Coupling the torpedo microplate-receptor binding assay with mass spectrometry to detect cyclic imine neurotoxins.
Rómulo Aráoz
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Suzanne Ramos
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Franck Pelissier
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Vincent Guérineau
,
Evelyne Benoit
et al.
Article dans une revue
hal-00769970v1
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|
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First direct fluorescence polarization assay for the detection and quantification of spirolides in mussel samples.
Paz Otero
,
Amparo Alfonso
,
Carmen Alfonso
,
Rómulo Aráoz
,
Jordi Molgó
et al.
Article dans une revue
istex
hal-00637237v1
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Synthesis of the gymnodimine tetrahydrofuran core through a Ueno-Stork radical cyclization.
Sylvestre Toumieux
,
Redouane Beniazza
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Valérie Desvergnes
,
Rómulo Aráoz
,
Jordi Molgó
et al.
Article dans une revue
hal-00586248v1
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6,6-Spiroimine analogs of (-)-gymnodimine A: synthesis and biological evaluation on nicotinic acetylcholine receptors.
Leslie Duroure
,
Thierry Jousseaume
,
Rómulo Aráoz
,
Elvina Barré
,
Pascal Retailleau
et al.
Article dans une revue
hal-00637236v1
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|
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Spiroimine toxins in complex with nicotinic acetylcholine receptors: structure and dynamics
Romulo Araoz
,
Laurent Chabaud
,
Catherine Guillou
,
Jordi Molgó
,
Bogdan Iorga
Article dans une revue
hal-00647637v1
|
|
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Solid-phase receptor-based assay for the detection of cyclic imines by chemiluminescence, fluorescence, or colorimetry.
Laura P Rodríguez
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Natalia Vilariño
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Jordi Molgó
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Rómulo Aráoz
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Alvaro Antelo
et al.
Article dans une revue
hal-00637241v1
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IP 3 receptor-mediated Ca ( 2+) signaling and autophagy induction are interrelated.
Jean-Paul Decuypere
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Tomas Luyten
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Raf Ponsaerts
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Autophagy, 2011, 7 (12), pp.1472-1489
Article dans une revue
hal-00683625v1
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Total synthesis of pinnatoxins A and G and revision of the mode of action of pinnatoxin A.
Romulo Araoz
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Jordi Molgó
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Bogdan I Iorga
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Carole Fruchart-Gaillard
et al.
Article dans une revue
hal-00634136v1
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Quantitative Determination of Gymnodimine-A by High Performance Liquid Chromatography in Contaminated Clams from Tunisia Coastline.
Riadh Marrouchi
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Faten Dziri
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Nawel Belayouni
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Asma Hamza
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Evelyne Benoit
et al.
Article dans une revue
istex
hal-00449049v1
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Isolation and pharmacological characterization of AdTx1, a natural peptide displaying specific insurmountable antagonism of the alpha(1A)-adrenoceptor.
L. Quinton
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Emmanuelle Girard
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A. Maiga
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M. Rekik
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P. Lluel
et al.
Article dans une revue
hal-00426559v1
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Dual action of a dinoflagellate-derived precursor of Pacific ciguatoxins (P-CTX-4B) on voltage-dependent K(+) and Na(+) channels of single myelinated axons.
Sébastien Schlumberger
,
César Mattei
,
Jordi Molgó
,
Evelyne Benoit
Article dans une revue
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hal-00406846v1
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Special issue on "Ciguatera and Related Biotoxins
Jordi Molgó
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Dominique Laurent
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Serge Pauillac
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Mireille Chinain
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Being Yeeting
Article dans une revue
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hal-00506123v1
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Essential Regulation of Cell Bioenergetics by Constitutive InsP(3) Receptor Ca(2+) Transfer to Mitochondria.
César Cárdenas
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Ian Smith
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Thi Bui
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Jordi Molgó
et al.
Article dans une revue
hal-00506136v1
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Detection of 13, 19-didesmethyl C spirolide by fluorescence polarization using Torpedo electrocyte membranes.
Eva S Fonfría
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Natalia Vilariño
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Jordi Molgó
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Rómulo Aráoz
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Paz Otero
et al.
Article dans une revue
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hal-00474310v1
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Differential entry of Botulinum Neurotoxin A into neuronal and intestinal cells: an ultrastructural approach
Aurélie Couesnon
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Cesare Colasante
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Jordi Molgó
,
Michel Popoff
Article dans une revue
pasteur-01758348v1
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IP(3)-dependent, post-tetanic calcium transients induced by electrostimulation of adult skeletal muscle fibers.
Mariana Casas
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Reinaldo Figueroa
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Gonzalo Jorquera
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Matías Escobar
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Jordi Molgó
et al.
Article dans une revue
hal-00586251v1
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Parallel activation of Ca(2+)-induced survival and death pathways in cardiomyocytes by sorbitol-induced hyperosmotic stress.
M. Chiong
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V. Parra
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V. Eisner
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C. Ibarra
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C. Maldonado
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Article dans une revue
hal-00506103v1
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Parazoanthoxanthin A blocks Torpedo nicotinic acetylcholine receptors.
Klara Bulc Rozman
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Rómulo Aráoz
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Kristina Sepčić
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Jordi Molgó
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Dušan Suput
Article dans une revue
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hal-00464523v1
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Analysis of Caribbean ciguatoxin-1 effects on frog myelinated axons and the neuromuscular junction.
César Mattei
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Michel Marquais
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Sébastien Schlumberger
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Jordi Molgó
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Jean-Paul Vernoux
et al.
Article dans une revue
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hal-00408913v1
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Ciguatoxin-induced catecholamine secretion in bovine chromaffin cells: Mechanism of action and reversible inhibition by brevenal.
Truong D Nguyen-Huu
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César Mattei
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Peter J Wen
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Article dans une revue
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hal-00422943v1
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Neurotoxic cyanobacterial toxins.
Rómulo Aráoz
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Jordi Molgó
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Nicole Tandeau de Marsac
Article dans une revue
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hal-00409807v1
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Structural determinants in phycotoxins and AChBP conferring high affinity binding and nicotinic AChR antagonism.
Yves Bourne
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Zoran Radic
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Rómulo Aráoz
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Todd T Talley
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Evelyne Benoit
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Proceedings of the National Academy of Sciences of the United States of America, 2010, 107 (13), pp.6076-81. ⟨10.1073/pnas.0912372107⟩
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hal-00464306v1
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Feasibility of gymnodimine and 13-desmethyl C spirolide detection by fluorescence polarization using a receptor-based assay in shellfish matrixes.
Eva S Fonfría
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Natalia Vilariño
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Begoña Espiña
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M. Carmen Louzao
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Mercedes Álvarez
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Article dans une revue
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hal-00426419v1
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Abnormal distribution of inositol 1,4,5-trisphosphate receptors in human muscle can be related to altered calcium signals and gene expression in Duchenne dystrophy-derived cells.
César Cárdenas
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Nevenka Juretic
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Jorge A Bevilacqua
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Isaac E García
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Reinaldo Figueroa
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Article dans une revue
hal-00474333v1
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The marine polyether gambierol enhances muscle contraction and blocks a transient K(+) current in skeletal muscle cells.
Sébastien Schlumberger
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Gilles Ouanounou
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Emmanuelle Girard
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Makoto Sasaki
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Haruhiko Fuwa
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Article dans une revue
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hal-00506109v1
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Sustained synaptic-vesicle recycling by bulk endocytosis contributes to the maintenance of high-rate neurotransmitter release stimulated by glycerotoxin.
Frédéric A. Meunier
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Tam H Nguyen
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Cesare Colasante
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Fujun Luo
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Robert K P Sullivan
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Article dans une revue
hal-00464518v1
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Isolation and pharmacological characterization of AdTx1, a natural peptide displaying specific insurmountable antagonism of the α1A-adrenoceptor
L. Quinton
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Emmanuelle Girard
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A. Maiga
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M. Rekik
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P. Lluel
et al.
Article dans une revue
cea-02000545v1
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Ligand-binding assays for cyanobacterial neurotoxins targeting cholinergic receptors.
Rómulo Aráoz
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Natalia Vilariño
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Luis M Botana
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Jordi Molgó
Article dans une revue
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hal-00466393v1
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The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1.
J. M. Vicencio
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A. W. E. Jones
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hal-00378189v1
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The extract of Ginkgo biloba EGb 761 reactivates a juvenile profile in the skeletal muscle of sarcopenic rats by transcriptional reprogramming.
Caroline Bidon
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Jordi Molgó
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Anne Wierinckx
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Sabine de La Porte
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Article dans une revue
hal-00449319v1
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Marine toxins potently affecting neurotransmitter release.
Frédéric A. Meunier
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César Mattei
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Jordi Molgó
Article dans une revue
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hal-00308524v1
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Mécanismes d'action des toxines et neurotoxines botuliques
Bernard Poulain
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Etienne Lonchamp
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Emmanuel Jover
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Michel R. Popoff
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Jordi Molgó
Article dans une revue
hal-00406643v1
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Resistance to D-tubocurarine of the rat diaphragm as compared to a limb muscle: influence of quantal transmitter release and nicotinic acetylcholine receptors.
Tu Nguyen-Huu
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Jordi Molgó
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Denis Servent
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Philippe Duvaldestin
Article dans une revue
hal-00377886v1
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Detection of gymnodimine-A and 13-desmethyl C spirolide phycotoxins by fluorescence polarization.
Natalia Vilariño
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Eva S Fonfría
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Jordi Molgó
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Rómulo Aráoz
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Luis M Botana
Article dans une revue
hal-00378092v1
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Evidence of a dosage effect and a physiological endplate acetylcholinesterase deficiency in the first mouse models mimicking Schwartz-Jampel syndrome neuromyotonia.
Morgane Stum
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Emmanuelle Girard
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Marie Bangratz
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Véronique Bernard
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Marc Herbin
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hal-00335149v1
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Fluorescent agonists for the Torpedo nicotinic acetylcholine receptor.
Florian Krieger
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Alexandre Mourot
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Rómulo Aráoz
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Florence Kotzyba-Hibert
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Jordi Molgó
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Article dans une revue
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hal-00289840v1
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A non-radioactive ligand-binding assay for detection of cyanobacterial anatoxins using Torpedo electrocyte membranes.
Rómulo Aráoz
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Michael Herdman
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Rosmarie Rippka
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Aurélie Ledreux
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Jordi Molgó
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Article dans une revue
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hal-00304222v1
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How do the Botulinum Neurotoxins block neurotransmitter release: from botulism to the molecular mechanism of action
Bernard Poulain
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Michel R. Popoff
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Jordi Molgó
Article dans une revue
hal-00303601v1
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Genetic ablation of acetylcholinesterase alters muscle function in mice.
Alban Vignaud
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Françoise Fougerousse
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Etienne Mouisel
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Christelle Bertrand
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Beatrice Bonafos
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Article dans une revue
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hal-00289869v1
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Sodium-dependent action potentials induced by brevetoxin-3 trigger both IP3 increase and intracellular Ca2+ release in rat skeletal myotubes.
José Luis Liberona
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César Cárdenas
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Roberto Reyes
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Jorge Hidalgo
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Jordi Molgó
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hal-00203374v1
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Effects of equinatoxin II on isolated guinea pig taenia caeci muscle contractility and intracellular Ca2+.
Robert Frangež
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Dusan Suput
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Jordi Molgó
Article dans une revue
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hal-00289853v1
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A mouse model for congenital myasthenic syndrome due to MuSK mutations reveals defects in structure and function of neuromuscular junctions.
Frédéric Chevessier
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Emmanuelle Girard
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Jordi Molgó
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Sönke Bartling
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Jeanine Koenig
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Article dans une revue
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hal-00335021v1
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Are cyanobacteria involved in Ciguatera Fish Poisoning-like outbreaks in New-Caledonia?
Dominique Laurent
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A.S. Kerbrat
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H.T. Daruis
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Emmanuelle Girard
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S. Golubic
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Article dans une revue
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hal-00203370v1
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Regulation of autophagy by the inositol trisphosphate receptor.
Alfredo Criollo
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Maria Chiara Maiuri
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Ezgi Tasdemir
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I. Vitale
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A. A. Fiebig
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Article dans une revue
hal-00216049v1
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Mechanisms involved in the swelling of erythrocytes caused by Pacific and Caribbean ciguatoxins
Martin-Pierre Sauviat
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Raphaële Boydron-Le Garrec
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Jean-Baptiste Masson
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Richard L. Lewis
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Jean-Paul Vernoux
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Article dans une revue
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hal-00087786v1
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Puroindoline-a and α1-purothionin form ion channels in giant liposomes but exert different toxic actions on murine cells
Paola Llanos
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Mauricio Henriquez
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Jasmina Minic
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Khalil Elmorjani
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Didier Marion
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Article dans une revue
hal-00023691v1
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Brain-derived neurotrophic factor facilitates in vivo internalization of tetanus neurotoxin C-terminal fragment fusion proteins in mature mouse motor nerve terminals.
Sylvie Roux
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Cécile Saint Cloment
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Thomas Curie
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Emmanuelle Girard
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Francisco-Javier Miana Mena
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Article dans une revue
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hal-00105586v1
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Apport d'un modèle murin de neuropathie démyélinisante inflammatoire au développement de thérapeutiques : caractérisations fonctionnelle et morphologique. [A mouse model of inflammatory demyelinating neuropathy for the development of therapeutics: electrophysiological and morphological characterizations]
Evelyne Benoit
,
Carmen Cifuentes-Diaz
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Jordi Molgó
Article dans une revue
hal-00168872v1
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Remodeling of the neuromuscular junction in mice with deleted exons 5 and 6 of acetylcholinesterase.
Emmanuelle Girard
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Véronique Bernard
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Shelley Camp
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Palmer Taylor
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Eric Krejci
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Journal of Molecular Neuroscience, 2006, 30 (1-2), pp.99-100
Article dans une revue
hal-00124700v1
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Glycerotoxin stimulates neurotransmitter release from N-type Ca2+ channel expressing neurons.
Mitja Schenning
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Dustin T. Proctor
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Lotten Ragnarsson
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Julien Barbier
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Nickolas A. Lavidis
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Article dans une revue
hal-00087596v1
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Outcome of acetylcholinesterase deficiency for neuromuscular functioning
E. Mouisel
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B. Blondet
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P. Escourrou
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Arnaud Chatonnet
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Jordi Molgó
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Article dans une revue
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hal-00087591v1
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Ability of some plant extracts , traditionally used to treat ciguatera fish poisoning, to prevent the in vitro neurotoxicity produced by sodium channel activators.
Raphaële Boydron-Le Garrec
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Evelyne Benoit
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Martin-Pierre Sauviat
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Richard J. Lewis
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Jordi Molgó
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Article dans une revue
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hal-00086982v1
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Nuclear inositol 1,4,5-trisphosphate receptors regulate local Ca2+ transients and modulate cAMP response element binding protein phosphorylation.
César Cárdenas
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José Luis Liberona
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Jordi Molgó
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Cesare Colasante
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Gregory A. Mignery
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Article dans une revue
hal-00098663v1
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Xestospongin B, a competitive inhibitor of IP3-mediated Ca2+ signalling in cultured rat myotubes, isolated myonuclei, and neuroblastoma (NG108-15) cells
Enrique Jaimovich
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César Mattei
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José Luis Liberona
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Cesar Cárdenas
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Manuel Estrada
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Article dans une revue
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hal-00086080v1
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Botulinal neurotoxins : revival of an old killer
Cesare Montecucco
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Jordi Molgó
Article dans une revue
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hal-00088165v1
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Synaptic remodeling at the skeletal neuromuscular junction of acetylcholinesterase knockout mice and its physiological relevance
Emmanuelle Girard
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Julien Barbier
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Arnaud Chatonnet
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E. Krejci
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Jordi Molgó
Article dans une revue
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hal-00021454v1
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Utilisation du fragment C-terminal de la neurotoxine tétanique pour visualiser et analyser des connexions neuronales et pour le transfert d'une activité biologique associée
Sylvie Roux
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Cécile Saint Cloment
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Thomas Curie
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Emmanuelle Girard
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Philippe Brûlet
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Article dans une revue
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hal-00109580v1
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Internalization of a GFP-tetanus toxin C-terminal fragment fusion protein at mature mouse neuromuscular junctions.
Sylvie Roux
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Cesare Colasante
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Cécile Saint Cloment
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Julien Barbier
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Thomas Curie
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Article dans une revue
istex
hal-00109564v1
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Neuronal and muscular alterations caused by two wheat endosperm proteins, puroindoline-a and alpha1-purothionin, are due to ion pore formation.
Paola Llanos
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Mauricio Henriquez
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Jasmina Minic
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Khalil Elmorjani
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Didier Marion
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Article dans une revue
hal-00139885v1
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Electrophysiological and morphological characterization of a case of autosomal recessive congenital myasthenic syndrome with acetylcholine receptor deficiency due to a N88K rapsyn homozygous mutation.
Eriko Yasaki
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Cassandra Prioleau
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Julien Barbier
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Pascale Richard
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Frédéric Andreux
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Article dans une revue
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hal-00136526v1
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Isolation and characterization of Psalmopeotoxin I and II: two novel antimalarial peptides from the venom of the tarantula Psalmopoeus cambridgei.
Soo-Jin Choi
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Romain Parent
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Carole Guillaume
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Christiane Deregnaucourt
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Christiane Delarbre
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Article dans une revue
hal-00136618v1
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Impaired neuromuscular transmission and skeletal muscle fiber necrosis in mice lacking Na/Ca exchanger 3.
Sophie Sokolow
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Mario Manto
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Philippe Gailly
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Jordi Molgó
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Clarisse Vandebrouck
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Article dans une revue
hal-00136504v1
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NMR solution structures of delta-conotoxin EVIA from Conus ermineus that selectively acts on vertebrate neuronal Na+ channels.
Laurent Volpon
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Hung Lamthanh
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Julien Barbier
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Nicolas Gilles
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Jordi Molgó
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Article dans une revue
hal-00136554v1
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Contryphan-Vn: a modulator of Ca2+-dependent K+ channels.
Gabriella Raybaudi Massilia
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Tommaso Eliseo
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Francoise Grolleau
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Bruno Lapied
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Julien Barbier
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Article dans une revue
istex
hal-00188894v1
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IP3 receptors and associated Ca2+ signals localize to satellite cells and to components of the neuromuscular junction in skeletal muscle.
Jeanne A Powell
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Jordi Molgó
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Dany S Adams
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Cesare Colasante
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Aislinn Williams
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Journal of Neuroscience, 2003, 23 (23), pp.8185-92
Article dans une revue
hal-00188162v1
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A synthetic weak neurotoxin binds with low affinity to Torpedo and chicken alpha7 nicotinic acetylcholine receptors.
Siew Lay Poh
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Gilles Mourier
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Robert Thai
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Arunmozhiarasi Armugam
,
Jordi Molgó
et al.
Article dans une revue
hal-00193986v1
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Botulinum neurotoxins: from paralysis to recovery of functional neuromuscular transmission.
Frédéric A. Meunier
,
Giampietro Schiavo
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Jordi Molgó
Article dans une revue
istex
hal-00193833v1
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Glycerotoxin from Glycera convoluta stimulates neurosecretion by up-regulating N-type Ca2+ channel activity.
Frédéric A. Meunier
,
Zhong-Ping Feng
,
Jordi Molgó
,
Gerald W Zamponi
,
Giampietro Schiavo
Article dans une revue
hal-00189121v1
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Ionic mechanisms involved in the nodal swelling of myelinated axons caused by marine toxins.
Evelyne Benoit
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César Mattei
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Gilles Ouanounou
,
Frédéric A. Meunier
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Dusan Suput
et al.
Cellular and Molecular Biology Letters, 2002, 7 (2), pp.317-321
Article dans une revue
hal-00186071v1
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Regulation of acetylcholine release by muscarinic receptors at the mouse neuromuscular junction depends on the activity of acetylcholinesterase.
Jasmina Minic
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Jordi Molgó
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Evert Karlsson
,
Eric Krejci
Article dans une revue
istex
hal-00193823v1
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Vesicle size and transmitter release at the frog neuromuscular junction when quantal acetylcholine content is increased or decreased.
William van Der Kloot
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Jordi Molgó
,
Roger Cameron
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Cesare Colasante
Article dans une revue
hal-00193969v1
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|
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Pacific ciguatoxin-1b effect over Na+ and K+ currents, inositol 1,4,5-triphosphate content and intracellular Ca2+ signals in cultured rat myotubes.
Jorge Hidalgo
,
José Luis Liberona
,
Jordi Molgó
,
Enrique Jaimovich
Article dans une revue
hal-00189135v1
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5',6'-dehydroguiachrysine and 5',6'-dehydroguiaflavine, two curarizing quaternary indole alkaloids from the stem bark of Strychnos guianensis.
Jacques Penelle
,
Philippe Christen
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Jordi Molgó
,
Monique Tits
,
Viviane Brandt
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Article dans une revue
istex
hal-00194146v1
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Scorpion alpha and alpha-like toxins differentially interact with sodium channels in mammalian CNS and periphery.
Nicolas Gilles
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Haijun Chen
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Harry Wilson
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Frédéric Le Gall
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Gonzalo Montoya
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Article dans une revue
istex
hal-00199357v1
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Quaternary indole alkaloids from the stem bark of Strychnos guianensis.
Jacques Penelle
,
Monique Tits
,
Philippe Christen
,
Jordi Molgó
,
Viviane Brandt
et al.
Article dans une revue
istex
hal-00196468v1
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Regulated expression of the proteoglycan SPOCK in the neuromuscular system.
Carmen Cifuentes-Diaz
,
Patrick M. Alliel
,
Frédéric Charbonnier
,
Sabine de La Porte
,
Jordi Molgó
et al.
Article dans une revue
istex
hal-00199646v1
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|
Effects of trachynilysin, a protein isolated from stonefish (Synanceia trachynis) venom, on frog atrial heart muscle.
Martin-Pierre Sauviat
,
Frédéric A. Meunier
,
Arnold S. Kreger
,
Jordi Molgó
Article dans une revue
istex
hal-00199670v1
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Recycling and refilling of transmitter quanta at the frog neuromuscular junction.
William van Der Kloot
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Cesare Colasante
,
Roger Cameron
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Jordi Molgó
The Journal of Physiology, 2000, 523 Pt 1, pp.247-58
Article dans une revue
hal-00196478v1
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Hyperosmolar d-mannitol reverses the increased membrane excitability and the nodal swelling caused by Caribbean ciguatoxin-1 in single frog myelinated axons
César Mattei
,
Jordi Molgó
,
Michel Marquais
,
Jean-Paul Vernoux
,
Evelyne Benoit
Article dans une revue
istex
hal-02127438v1
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Neurotoxins targetting receptor site 5 of voltage-dependent sodium channels increase the nodal volume of myelinated axons
César Mattei
,
Marie-Yasmine Dechraoui
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Jordi Molgó
,
Frédéric Meunier
,
Anne-Marie Legrand
et al.
Article dans une revue
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hal-02127473v1
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Ciguatoxines et brévétoxines : dissection de leurs actions neurobiologiques
César Mattei
,
Jordi Molgó
,
Anne-Marie Legrand
,
Evelyne Benoit
Article dans une revue
istex
hal-02127445v1
|
|
|
Ciguatoxins and brevetoxins: dissection of the neurobiological actions
César Mattei
,
Jordi Molgó
,
Anne-Marie Legrand
,
Evelyne Benoit
Journal de la Société de Biologie, 1999
Article dans une revue
hal-04215239v1
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A new conotoxin isolated from Conus consors venom acting selectively on axons and motor nerve terminals through a Na + -dependent mechanism
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Article dans une revue
istex
hal-02127463v1
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The wheat proteins puroindoline-a and α1-purothionin induce nodal swelling in myelinated axons
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Didier Marion
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Evelyne Benoit
Article dans une revue
hal-02330647v1
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The peripheral nerve and the neuromuscular junction are affected in the tenascin-C-deficient mouse.
C. Cifuentes-Diaz
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E. Velasco
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Frédéric A. Meunier
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D. Goudou
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Cellular and Molecular Biology, 1998, 44 (2), pp.357-79
Article dans une revue
hal-00471168v1
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Incorporation of synaptotagmin II to the axolemma of botulinum type-A poisoned mouse motor endings during enhanced quantal acetylcholine release.
Denise Angaut-Petit
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Masami Takahashi
Article dans une revue
istex
hal-00470699v1
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