Juan Reguera

Identifiants chercheurs

IdHAL :

juan-reguera

ORCID :

0000-0003-4977-7948

ResearcherID :

A-7551-2017

Publications

Article dans une revue (27)

Alphavirus nsP3 organizes into tubular scaffolds essential for infection and the cytoplasmic granule architecture Vasiliya Kril,Michael Hons,Celine Amadori,Claire Zimberger,Laurine Coutureet al. Nature Communications, 2024, 15, pp.8106. ⟨10.1038/s41467-024-51952-z⟩ Article dans une revue hal-04717331v1
Biophysical and structural study of La Crosse virus endonuclease inhibition for the development of new antiviral options Mikael Feracci,Sergio Hernandez,Laura Garlatti,Clemence Mondielli,Renaud Vincentelliet al. International Union of Crystallography journal, 2024, 11 (3), pp.374-383. ⟨10.1107/S205225252400304X⟩ Article dans une revue hal-04746756v1
Structural basis and dynamics of Chikungunya alphavirus RNA capping by nsP1 capping pores Rhian Jones,Michael Hons,Nadia Rabah,Noelia Zamarreño,Rocío Arranzet al. Proceedings of the National Academy of Sciences of the United States of America, 2023, 120 (12), ⟨10.1073/pnas.2213934120⟩ Article dans une revue hal-04129138v1
Structures of active Hantaan virus polymerase uncover the mechanisms of Hantaviridae genome replication Quentin Durieux Trouilleton,Sergio Barata-García,Benoît Arragain,Juan Reguera,Hélène Malet Nature Communications, 2023, 14 (1), pp.2954. ⟨10.1038/s41467-023-38555-w⟩ Article dans une revue hal-04129164v1
Structural basis of Ty1 integrase tethering to RNA polymerase III for targeted retrotransposon integration Phong Quoc Nguyen,Sonia Huecas,Amna Asif-Laidin,Adrián Plaza-Pegueroles,Beatrice Capuzziet al. Nature Communications, 2023, 14 (1), pp.1729. ⟨10.1038/s41467-023-37109-4⟩ Article dans une revue hal-04056067v1
Structural Insights into the Mechanisms of Action of Functionally Distinct Classes of Chikungunya Virus Nonstructural Protein 1 Inhibitors Kristina Kovacikova,Marina Gorostiola González,Rhian Jones,Juan Reguera,Alba Giganteet al. Antimicrobial Agents and Chemotherapy, 2021, 65 (7), ⟨10.1128/AAC.02566-20⟩ Article dans une revue hal-03366195v1
Ty1 integrase is composed of an active N-terminal domain and a large disordered C-terminal module dispensable for its activity $in\ vitro$ Phong Quoc Nguyen,Christine Conesa,Elise Rabut,Gabriel Bragagnolo,Célia Gouzerhet al. Journal of Biological Chemistry, 2021, 297 (4), pp.101093. ⟨10.1016/j.jbc.2021.101093⟩ Article dans une revue hal-03402697v1
Pre-initiation and elongation structures of full-length La Crosse virus polymerase reveal functionally important conformational changes Benoît Arragain,Grégory Effantin,Piotr Gerlach,Juan Reguera,Guy Schoehnet al. Nature Communications, 2020, 11 (1), pp.3590. ⟨10.1038/s41467-020-17349-4⟩ Article dans une revue hal-02907948v1
Capping pores of alphavirus nsP1 gate membranous viral replication factories Rhian Jones,Gabriel Bragagnolo,Rocío Arranz,Juan Reguera Nature, 2020, 589 (7843), pp.615 - 619. ⟨10.1038/s41586-020-3036-8⟩ Article dans une revue hal-03139499v1
Structure and function of the Toscana virus cap-snatching endonuclease Rhian Jones,Sana Lessoued,Kristina Meier,Stéphanie Devignot,Sergio Barata-Garcíaet al. Nucleic Acids Research, 2019, 47, pp.10914-10930. ⟨10.1093/nar/gkz838⟩ Article dans une revue hal-02611184v1
High resolution cryo-EM structure of the helical RNA-bound Hantaan virus nucleocapsid reveals its assembly mechanisms Benoît Arragain,Juan Reguera,Ambroise Desfosses,Irina Gutsche,Guy Schoehnet al. eLife, 2019, 8, ⟨10.7554/eLife.43075⟩ Article dans une revue hal-01987302v1
Allosteric inhibition of aminopeptidase N functions related to tumor growth and virus infection C Santiago,G Mudgal,J Reguera,R Recacha,Sebastien Albrechtet al. Scientific Reports, 2017, 7, pp.46045. ⟨10.1038/srep46045⟩ Article dans une revue hal-02154721v1
Structural insights into reptarenavirus cap-snatching machinery Maria Rosenthal,Nadja Gogrefe,Dominik Vogel,Juan Reguera,Bianka Rauschenbergeret al. PLoS Pathogens, 2017, 13 (5), pp.e1006400. ⟨10.1371/journal.ppat.1006400⟩ Article dans une revue hal-05251346v1
Transcription and replication mechanisms of Bunyaviridae and Arenaviridae L proteins Francois Ferron,Friedemann Weber,Juan de La Torre,Juan Reguera Virus Research, 2017, 234, pp.118 - 134. ⟨10.1016/j.virusres.2017.01.018⟩ Article dans une revue hal-01802833v1
Towards a structural understanding of RNA synthesis by negative strand RNA viral polymerases Juan Reguera,Piotr Gerlach,Stephen Cusack Current Opinion in Structural Biology, 2016, 36, pp.75-84. ⟨10.1016/j.sbi.2016.01.002⟩ Article dans une revue hal-05251380v1
Comparative Structural and Functional Analysis of Bunyavirus and Arenavirus Cap-Snatching Endonucleases Juan Reguera,Piotr Gerlach,Maria Rosenthal,Stephanie Gaudon,Francesca Cosciaet al. PLoS Pathogens, 2016, 12 (6), pp.e1005636. ⟨10.1371/journal.ppat.1005636⟩ Article dans une revue hal-05251270v1
Atomic Structure and Biochemical Characterization of an RNA Endonuclease in the N Terminus of Andes Virus L Protein Yaiza Fernández-García,Juan Reguera,Carola Busch,Gregor Witte,Oliberto Sánchez-Ramoset al. PLoS Pathogens, 2016, 12 (6), pp.e1005635. ⟨10.1371/journal.ppat.1005635⟩ Article dans une revue hal-05251225v1
Structural Insights into Bunyavirus Replication and Its Regulation by the vRNA Promoter Juan Reguera,Gaurav Mudgal,César Santiago,José Casasnovas Cell, 2015, 161 (6), pp.1267-1279. ⟨10.1016/j.cell.2015.05.006⟩ Article dans une revue hal-01993602v1
Segmented negative strand RNA virus nucleoprotein structure Juan Reguera,Stephen Cusack,Daniel Kolakofsky Current Opinion in Virology, 2014, 5, pp.7-15. ⟨10.1016/j.coviro.2014.01.003⟩ Article dans une revue istex hal-05251312v1
Structural basis for encapsidation of genomic RNA by La Crosse Orthobunyavirus nucleoprotein Juan Reguera,Hélène Malet,Friedemann Weber,Stephen Cusack Proceedings of the National Academy of Sciences of the United States of America, 2013, 110, pp.7246 - 7251. ⟨10.1073/pnas.1302298110⟩ Article dans une revue hal-05251335v1
Structural Bases of Coronavirus Attachment to Host Aminopeptidase N and Its Inhibition by Neutralizing Antibodies Juan Reguera,César Santiago,Gaurav Mudgal,Desiderio Ordoño,Luis Enjuaneset al. PLoS Pathogens, 2012, 8 (8), pp.e1002859. ⟨10.1371/journal.ppat.1002859⟩ Article dans une revue hal-05251322v1
Antigenic modules in the N-terminal S1 region of the transmissible gastroenteritis virus spike protein Juan Reguera,Desiderio Ordoño,César Santiago,Luis Enjuanes,José Casasnovas Journal of General Virology, 2011, 92 (5), pp.1117-1126. ⟨10.1099/vir.0.027607-0⟩ Article dans une revue hal-05251215v1
Bunyaviridae RNA Polymerases (L-Protein) Have an N-Terminal, Influenza-Like Endonuclease Domain, Essential for Viral Cap-Dependent Transcription Juan Reguera,Friedemann Weber,Stephen Cusack PLoS Pathogens, 2010, 6 (9), pp.e1001101. ⟨10.1371/journal.ppat.1001101⟩ Article dans une revue hal-05251262v1
Nuclear Transport of Trimeric Assembly Intermediates Exerts a Morphogenetic Control on the Icosahedral Parvovirus Capsid Laura Riolobos,Juan Reguera,Mauricio Mateu,José Almendral Journal of Molecular Biology, 2006, 357 (3), pp.1026-1038. ⟨10.1016/j.jmb.2006.01.019⟩ Article dans une revue istex hal-05251298v1
Functional Relevance of Amino Acid Residues Involved in Interactions with Ordered Nucleic Acid in a Spherical Virus Juan Reguera,Esther Grueso,Aura Carreira,Cristina Sánchez-Martínez,José M Almendralet al. Journal of Biological Chemistry, 2005, 280 (18), pp.17969 - 17977. ⟨10.1074/jbc.m500867200⟩ Article dans une revue hal-05251278v1
Role of interfacial amino acid residues in assembly, stability, and conformation of a spherical virus capsid Juan Reguera,Aura Carreira,Laura Riolobos,José María Almendral,Mauricio Mateu Proceedings of the National Academy of Sciences of the United States of America, 2004, 101 (9), pp.2724-2729. ⟨10.1073/pnas.0307748101⟩ Article dans une revue hal-05251305v1
In Vitro Disassembly of a Parvovirus Capsid and Effect on Capsid Stability of Heterologous Peptide Insertions in Surface Loops Aura Carreira,Margarita Menéndez,Juan Reguera,José María Almendral,Mauricio G Mateu Journal of Biological Chemistry, 2003, 279 (8), pp.6517 - 6525. ⟨10.1074/jbc.m307662200⟩ Article dans une revue hal-05251291v1

Chapitre d'ouvrage (1)

Negative Single-Stranded RNA Viruses (Mononegavirales): A Structural View Juan Reguera Encyclopedia of Virology, Elsevier, pp.345-351, 2021, ⟨10.1016/B978-0-12-814515-9.00105-3⟩ Chapitre d'ouvrage hal-03595539v1