Julien Barbier

Publications

Article dans une revue (39)

Inhibition of OSBP blocks retrograde trafficking by inducing partial Golgi degradation Nianzhe He,Laura Depta,Cecilia Rossetti,Lucie Caramelle,Marko Cigleret al. Nature Chemical Biology, 2025, 21 (2), pp.203-214. ⟨10.1038/s41589-024-01653-x⟩ Article dans une revue hal-05195923v1
A New Derivative of Retro-2 Displays Antiviral Activity against Respiratory Syncytial Virus Adrien Le Rouzic,Jenna Fix,Robin Vinck,Sandrine Kappler-Gratias,Romain Volmeret al. International Journal of Molecular Sciences, 2024, 25 (1), pp.415. ⟨10.3390/ijms25010415⟩ Article dans une revue hal-04408762v1
Endolysosomal channel TMEM 175 mediates antitoxin activity of DABMA Yu Wu,Jiamin Huang,Fei Zhang,Florence Guivel-Benhassine,Mathieu Hubertet al. FEBS Journal, 2024, 291 (18), pp.4142-4154. ⟨10.1111/febs.17242⟩ Article dans une revue pasteur-05109820v1
Autophagic degradation is involved in cell protection against ricin toxin Yu Wu,Clémence Taisne,Nassim Mahtal,Alison Forrester,Marion Lussignolet al. Toxins, 2023, 15 (5), pp.304. ⟨10.3390/toxins15050304⟩ Article dans une revue cea-04352580v1
Antiviral effects of ABMA and DABMA against Influenza virus In vitro and In vivo via regulating the endolysosomal pathway and autophagy Hongtao Liu,Chunlai Jiang,Yu Wu,Min Wu,Jiaxin Wuet al. International Journal of Molecular Sciences, 2022, 23 (7), pp.3940. ⟨10.3390/ijms23073940⟩ Article dans une revue cea-04352635v1
In vivo sustained release of the retrograde transport inhibitor retro-2.1 formulated in a thermosensitive hydrogel Robin Vinck,Laetitia Anvi Nguyen,Mathilde Munier,Lucie Caramelle,Diana Karpmanet al. International Journal of Molecular Sciences, 2022, 23, pp.14611. ⟨10.3390/ijms232314611⟩ Article dans une revue cea-04352592v1
An adamantamine derivative as a drug candidate for the treatment of visceral leishmaniasis Sébastien Pomel,Sandrine Cojean,Valérie Pons,Jean-Christophe Cintrat,Laetitia Nguyenet al. Journal of Antimicrobial Chemotherapy, 2021, 76 (10), pp.2640-2650. ⟨10.1093/jac/dkab226⟩ Article dans une revue cea-04352695v1
Structure–Activity Relationship Studies of Retro-1 Analogues against Shiga Toxin Hajer Abdelkafi,Aurélien Michau,Valérie Pons,Flora Ngadjeua,Alexandra Clergetet al. Journal of Medicinal Chemistry, 2020, 63 (15), pp.8114-8133. ⟨10.1021/acs.jmedchem.0c00298⟩ Article dans une revue hal-03320788v1
Shiga Toxin Uptake and Sequestration in Extracellular Vesicles Is Mediated by Its B-Subunit Annie Willysson,Anne-Lie Ståhl,Daniel Gillet,Julien Barbier,Jean-Christophe Cintratet al. Toxins, 2020, 12 (7), ⟨10.3390/toxins12070449⟩ Article dans une revue cea-03023143v1
Revisiting Old Ionophore Lasalocid as a Novel Inhibitor of Multiple Toxins Nassim Mahtal,Yu Wu,Jean-Christophe Cintrat,Julien Barbier,Emmanuel Lemichezet al. Toxins, 2020, 12 (1), pp.26. ⟨10.3390/toxins12010026⟩ Article dans une revue pasteur-02448862v1
Functional dissection of the retrograde Shiga toxin trafficking inhibitor Retro-2 Alison Forrester,Stefan Rathjen,Maria Daniela Garcia-Castillo,Collin Bachert,Audrey Couhertet al. Nature Chemical Biology, 2020, 16 (3), pp.327-336. ⟨10.1038/s41589-020-0474-4⟩ Article dans une revue hal-03321166v1
DABMA: A Derivative of ABMA with Improved Broad-Spectrum Inhibitory Activity of Toxins and Viruses Yu Wu,Valérie Pons,Romain Noël,Sabrina Kali,Olena Shtankoet al. ACS Medicinal Chemistry Letters, 2019, 10 (8), pp.1140-1147. ⟨10.1021/acsmedchemlett.9b00155⟩ Article dans une revue pasteur-02453943v1
Retro-2 and its dihydroquinazolinone derivatives inhibit filovirus infection Olena Shtanko,Yasuteru Sakurai,Ann Reyes,Romain Noël,Jean-Christophe Cintratet al. Antiviral Research, 2018, ⟨10.1016/j.antiviral.2017.11.016⟩ Article dans une revue hal-04352731v1
Antiviral Effects of ABMA against Herpes Simplex Virus Type 2 In Vitro and In Vivo Wenwen Dai,Yu Wu,Jinpeng Bi,Shuai Wang,Fang Liet al. Viruses, 2018, 10 (3), pp.119. ⟨10.3390/v10030119⟩ Article dans une revue cea-02432376v1
Antiviral Effect of Retro-2.1 against Herpes Simplex Virus Type 2 In Vitro Wen Wen Dai,Yu Wu,Jin Peng Bi,Jing Yu Wang,Shuai Wanget al. JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, 2018, ⟨10.4014/jmb.1712.12052⟩ Article dans une revue hal-04352689v1
Editorial : 23rd and 24th Meetings of the French Society of Toxinology (SFET): Special issue on &quot;Toxins: Immunity, Inflammation and Pain Evelyne Benoit,Julien Barbier,Jordi Molgó Toxicon, 2018, 149, pp.1 - 5. ⟨10.1016/j.toxicon.2018.04.020⟩ Article dans une revue hal-01828958v1
Screening of a drug library identifies inhibitors of cell intoxication by CNF1 Nassim Mahtal,Clémence Brewee,Sylvain Pichard,Orane Visvikis,Jean-Christophe Cintratet al. ChemMedChem, 2018, 13 (7), pp.754-761. ⟨10.1002/cmdc.201700631⟩ Article dans une revue hal-02448858v1
ABMA, a small molecule that inhibits intracellular toxins and pathogens by interfering with late endosomal compartments Yu Wu,Valérie Pons,Amélie Goudet,Laetitia Panigai,Annette Fischeret al. Scientific Reports, 2017, 7 (1), pp.15567. ⟨10.1038/s41598-017-15466-7⟩ Article dans une revue pasteur-01675662v1
Editorial : Special Issue on &quot;Toxins: New targets and new functions&quot;. Evelyne Benoit,Julien Barbier,Michel R Popoff,Grazyna Faure,Jordi Molgóet al. Toxicon, 2016, 116, pp.1-3. ⟨10.1016/j.toxicon.2016.03.012⟩ Article dans une revue hal-01306142v1
The Translocation Domain of Botulinum Neurotoxin A Moderates the Propensity of the Catalytic Domain to Interact with Membranes at Acidic pH Anne Araye,Amélie Goudet,Julien Barbier,Sylvain Pichard,Bruno Baronet al. PLoS ONE, 2016, 11 (4), pp.e0153401. ⟨10.1371/journal.pone.0153401⟩ Article dans une revue pasteur-01378747v1
Correction: The Translocation Domain of Botulinum Neurotoxin A Moderates the Propensity of the Catalytic Domain to Interact with Membranes at Acidic pH. Anne Araye,Amélie Goudet,Julien Barbier,Sylvain Pichard,Bruno Baronet al. PLoS ONE, 2016, pp.e0161743. ⟨10.1371/journal.pone.0161743⟩ Article dans une revue hal-01452079v1
Retrograde trafficking inhibitor of Shiga toxins reduces morbidity and mortality of mice infected with enterohemorrhagic &lt;em&gt;Escherichia coli&lt;/em&gt; Thomas Secher,Ayaka Shima,Karen Hinsinger,Jean Christophe Cintrat,Ludger Johanneset al. Antimicrobial Agents and Chemotherapy, 2015, 59 (8), pp.5010-5013. ⟨10.1128/AAC.00455-15⟩ Article dans une revue hal-02640796v1
Editorial : Special Issue on &quot;freshwater and marine toxins&quot;. Evelyne Benoit,César Mattei,Julien Barbier,Pascale Marchot,Jordi Molgóet al. Toxicon, 2014, 91, pp.1-4. ⟨10.1016/j.toxicon.2014.11.217⟩ Article dans une revue istex hal-01165542v1
Editorial : Special issue on &quot;toxins: from threats to benefits&quot;. Marie-France Martin-Eauclaire,Evelyne Benoit,Pascale Marchot,Julien Barbier,Jordi Molgóet al. Toxicon, 2013, 75, pp.1-2. ⟨10.1016/j.toxicon.2013.08.001⟩ Article dans une revue hal-00919888v1
The small molecule Retro-1 enhances the pharmacological actions of antisense and splice switching oligonucleotides Xin Ming,Kyle Carver,Michael Fisher,Romain Noël,Jean-Christophe Cintratet al. Nucleic Acids Research, 2013, 41 (6), pp.3673-3687. ⟨10.1093/nar/gkt066⟩ Article dans une revue cea-02432369v1
Inhibitors of the Cellular Trafficking of Ricin Julien Barbier,Céline Bouclier,Ludger Johannes,Daniel Gillet Toxins, 2012, 4, pp.15-27. ⟨10.3390/toxins4010015⟩ Article dans une revue cea-02432365v1
Solution and membrane-bound chaperone activity of the diphtheria toxin translocation domain towards the catalytic domain Anne Chassaing,Sylvain Pichard,Anne Araye-Guet,Julien Barbier,Vincent Forgeet al. FEBS Journal, 2011, 278 (23), pp.4516-45525. ⟨10.1111/j.1742-4658.2011.08053.x⟩ Article dans une revue hal-01138149v1
Inhibition of retrograde transport protects mice from lethal ricin challenge. Bahne Stechmann,Siau-Kun Bai,Emilie Gobbo,Roman Lopez,Goulven Mereret al. Cell, 2010, 141 (2), pp.231-42. ⟨10.1016/j.cell.2010.01.043⟩ Article dans une revue hal-00509058v1
Brain-derived neurotrophic factor facilitates in vivo internalization of tetanus neurotoxin C-terminal fragment fusion proteins in mature mouse motor nerve terminals. Sylvie Roux,Cécile Saint Cloment,Thomas Curie,Emmanuelle Girard,Francisco-Javier Miana Menaet al. European Journal of Neuroscience, 2006, 24 (6), pp.1546-1554. ⟨10.1111/j.1460-9568.2006.05030.x⟩ Article dans une revue istex hal-00105586v1
Glycerotoxin stimulates neurotransmitter release from N-type Ca2+ channel expressing neurons. Mitja Schenning,Dustin T. Proctor,Lotten Ragnarsson,Julien Barbier,Nickolas A. Lavidiset al. Journal of Neurochemistry, 2006, 98 (3), pp.894-904. ⟨10.1111/j.1471-4159.2006.03938.x⟩ Article dans une revue hal-00087596v1
Cholinesterases and the resistance of the mouse diaphragm to the effect of tubocurarine. Tu Nguyen-Huu,Alexandre Dobbertin,Julien Barbier,Jasmina Minic,Eric Krejciet al. Anesthesiology, 2005, 103 (4), pp.788-795 Article dans une revue hal-00129516v1
Xestospongin B, a competitive inhibitor of IP3-mediated Ca2+ signalling in cultured rat myotubes, isolated myonuclei, and neuroblastoma (NG108-15) cells Enrique Jaimovich,César Mattei,José Luis Liberona,Cesar Cárdenas,Manuel Estradaet al. FEBS Letters, 2005, 579(10), pp.2051-2057. ⟨10.1016/j.febslet.2005.02.053⟩ Article dans une revue istex hal-00086080v1
Synaptic remodeling at the skeletal neuromuscular junction of acetylcholinesterase knockout mice and its physiological relevance Emmanuelle Girard,Julien Barbier,Arnaud Chatonnet,E. Krejci,Jordi Molgó Chemico-Biological Interactions, 2005, 157-158, pp.87-96. ⟨10.1016/j.cbi.2005.10.010⟩ Article dans une revue istex hal-00021454v1
Internalization of a GFP-tetanus toxin C-terminal fragment fusion protein at mature mouse neuromuscular junctions. Sylvie Roux,Cesare Colasante,Cécile Saint Cloment,Julien Barbier,Thomas Curieet al. Molecular and Cellular Neuroscience, 2005, 30 (4), pp.572-582. ⟨10.1016/j.mcn.2005.05.008⟩ Article dans une revue istex hal-00109564v1
NMR solution structures of delta-conotoxin EVIA from Conus ermineus that selectively acts on vertebrate neuronal Na+ channels. Laurent Volpon,Hung Lamthanh,Julien Barbier,Nicolas Gilles,Jordi Molgóet al. Journal of Biological Chemistry, 2004, 279 (20), pp.21356-21366. ⟨10.1074/jbc.M309594200⟩ Article dans une revue hal-00136554v1
Electrophysiological and morphological characterization of a case of autosomal recessive congenital myasthenic syndrome with acetylcholine receptor deficiency due to a N88K rapsyn homozygous mutation. Eriko Yasaki,Cassandra Prioleau,Julien Barbier,Pascale Richard,Frédéric Andreuxet al. Neuromuscular Disorders, 2004, 14 (1), pp.24-32. ⟨10.1016/j.nmd.2003.07.002⟩ Article dans une revue istex hal-00136526v1
A delta-conotoxin from Conus ermineus venom inhibits inactivation in vertebrate neuronal Na+ channels but not in skeletal and cardiac muscles. Julien Barbier,Hung Lamthanh,Frédéric Le Gall,Philippe Favreau,Evelyne Benoitet al. Journal of Biological Chemistry, 2004, 279 (6), pp.4680-4685. ⟨10.1074/jbc.M309576200⟩ Article dans une revue hal-00136492v1
Degeneration and regeneration of murine skeletal neuromuscular junctions after intramuscular injection with a sublethal dose of Clostridium sordellii lethal toxin. Julien Barbier,Michel R Popoff,Jordi Molgó Infection and Immunity, 2004, 72 (6), pp.3120-3128. ⟨10.1128/IAI.72.6.3120-3128.2004⟩ Article dans une revue hal-00169722v1
Contryphan-Vn: a modulator of Ca2+-dependent K+ channels. Gabriella Raybaudi Massilia,Tommaso Eliseo,Francoise Grolleau,Bruno Lapied,Julien Barbieret al. Biochemical and Biophysical Research Communications, 2003, 303 (1), pp.238-46. ⟨10.1016/S0006-291X(03)00331-0⟩ Article dans une revue istex hal-00188894v1

Pré-publication, Document de travail (1)

A New Derivative of Retro-2 Displays Antiviral Activity against Respiratory Syncytial Virus Adrien Le Rouzic,Jenna Fix,Robin Vinck,Sandrine Kappler-Gratias,Romain Volmeret al. 2024 Pré-publication, Document de travail hal-04684074v1

N°spécial de revue/special issue (4)

Ribosome Inactivating Proteins: From Plant Defense to Treatments against Human Misuse or Diseases Julien Barbier,Daniel Gillet 2018, ⟨10.3390/toxins10040160⟩ N°spécial de revue/special issue hal-04352715v1
Toxins: New Targets and New Functions Jordi Molgó,Evelyne Benoit,Julien Barbier,Michel Popoff,Grazyna Faureet al. J. MOLGO, E. BENOIT, J. BARBIER, M.R. POPPOF, G. FAURE & D. SERVENT (Eds). Rencontres en Toxinologie « Toxins: New Targets and New Functions » organisées par la Société Française pour l'Etude des Toxines, Dec 2014, Paris, France. Toxicon, 116, 2016, Special issue of Toxicon, 0041-0101 N°spécial de revue/special issue hal-02334653v1
Freshwater and Marine Toxins Jordi Molgó,Evelyne Benoit,Julien Barbier,Pascale Marchot,Denis Servent J. MOLGO, E. BENOIT, J. BARBIER, P. MARCHOT & D. SERVENT (Eds). Rencontres en Toxinologie « Freshwater and Marine Toxins » organisées par la Société Française pour l'Etude des Toxines, Dec 2013, Paris, France. Toxicon, 91, 2014, Special issue of Toxicon, 0041-0101 N°spécial de revue/special issue hal-02334647v1
Toxins: From Threats to Benefits Jordi Molgó,Evelyne Benoit,Julien Barbier,Pascale Marchot,Denis Servent J. MOLGO, E. BENOIT, J. BARBIER, P. MARCHOT & D. SERVENT (Eds). Rencontres en Toxinologie « Toxins: From Threats to Benefits » organisées par la Société Française pour l'Etude des Toxines (2012), Dec 2012, Paris, France. Toxicon, 75, 2013, Special issue of Toxicon, 0041-0101 N°spécial de revue/special issue hal-02334645v1

Ouvrages (2)

Toxins and Ion transfers Julien Barbier,Evelyne Benoit,Nicolas Gilles,Daniel Ladant,Marie-France Martin-Eauclaireet al. SFET Publications, Gif-sur-Yvette, France, pp.123, 2011 Ouvrages hal-00738632v1
Advances and new technologies in Toxinology Julien Barbier,Evelyne Benoit,Pascale Marchot,César Mattei,Denis Servent SFET Publications, Gif-sur-Yvette, France, pp.186, 2010 Ouvrages hal-00738636v1

Communication dans un congrès (3)

Synaptic efficacy and remodelling at the neuromuscular junction of knockout mice deficient in acetylcholinesterase Emmanuelle Girard,Julien Barbier,Shelley Camp,Palmer Taylor,Arnaud Chatonnetet al. Conference Ladislav Tauc - The World of the Synapse: Molecular Basis, Pathologies and Drug Discovery, Dec 2004, Gif sur Yvette, France. pp.254-255 Communication dans un congrès hal-00291775v1
delta-Conopeptide EVIA isolated from Conus ermineus is a new pharmacological tool for discriminating sodium channel subtypes Julien Barbier,Hung Lamthanh,Frédéric Le Gall,Philippe Favreau,Evelyne Benoitet al. 2006, pp.247, ⟨10.1016/j.jphysparis.2005.12.020⟩ Communication dans un congrès istex hal-00125051v1
Synaptic remodeling at the skeletal neuromuscular junction of acetylcholinesterase knockout mice and its physiological relevance Emmanuelle Girard,Julien Barbier,Arnaud Chatonnet,Eric Krejci,Jordi Molgo 8.International Meeting on Cholinesterases, Sep 2004, Perugia, Italy. ⟨10.1016/j.cbi.2005.10.010⟩ Communication dans un congrès istex hal-02764464v1

Chapitre d'ouvrage (7)

Neuromuscular alterations and synaptic remodelling after exposure to clostridial toxins Julien Barbier,Michel R. Popoff,Jordi Molgó D. Gillet and L. Johannes. Recent Research Developments in Toxins from Bacteria and Other Organisms, Research Signpost, Kerala, India, pp.301-326, 2006, ISBN: 81-7736-268-2 Chapitre d'ouvrage hal-00105901v1
Bacterial toxins with intracellular targets Julien Barbier,Jordi Molgó S.G. Pandalai. Recent Research Developments in Cell Science (vol.1), Transworld Research Network, Trivandrum, Kerala, Inde, pp.217-239, 2004, Monographie - ISBN: 81-7895-112-6 Chapitre d'ouvrage hal-00183648v1
Synaptic transmission at AChE-/- and ColQ-/- knockout mouse neuromuscular junctions Jasmina Minic,Julien Barbier,Arnaud Chatonnet,Jordi Molgó N. Inestrosa & E. O. Campos. Cholinesterase in the Second Millennium : Biomolecular and Pathological Aspects, Diseño e Impresiones J&J Ltda, Chile, pp.19-23, 2004, ISBN: 956-299-127-X Chapitre d'ouvrage hal-00183322v1
Conotoxins targeting voltage-sensitive sodium channels Julien Barbier,Evelyne Benoit,Jordi Molgó P. Ascenzi F. Polticelli & P. Visca. Bacterial, Plant and Animal toxins, Research Signpost (Trivandrum, Kerala, India), pp.127-145, 2003, ISBN: 81-271-0037-4 Chapitre d'ouvrage hal-00189355v1
Implication des réserves intracellulaires de Ca2+ dans l'augmentation de la libération d'acétylcholine indépendante du Ca2+ externe et provoquée par la brévétoxine-3 Emmanuelle Girard,Julien Barbier,Evelyne Benoit,Dominique Laurent,Jordi Molgó F. Goudey-Perriere, E. Benoit, C. Bon & S. Puiseux-Dao. Toxinogenèse – Biosynthèse, ingénierie, polymorphisme, neutralisation des toxines, Elsevier, pp.81-86, 2003, ISBN: 2-84299-481-7 / Ean 13 : 9782842994815 Chapitre d'ouvrage hal-00189404v1
Les conotoxines: de nouveaux outils pour étudier la diversité des canaux Na+ sensibles au potentiel de membrane Julien Barbier,Evelyne Benoit,Jordi Molgó F. Goudey-Perriere, E. Benoit, C. Bon & S. Puiseux-Dao. Toxinogenèse – Biosynthèse, ingénierie, polymorphisme, neutralisation des toxines, Elsevier, pp.157-166, 2003, ISBN: 2-84299-481-7 / Ean 13 : 9782842994815 Chapitre d'ouvrage hal-00189402v1
Les toxines clostridiales de haut poids moléculaire agissant sur les petites protéines G Julien Barbier,Michel R Popoff,Michel Thieffry,Jordi Molgó F. Goudey-Perriere, C. Bon, S. Puiseux-Dao & M-P Sauviat. Toxines et recherches biomédicales (Coll. Rencontres en Toxinologie SFET), Elsevier, Paris, pp.65-74, 2002, ISBN: 2-84299-445-0 Chapitre d'ouvrage hal-00194105v1