Kerstin Bystricky Director MCD-CBIProfessor Molecular Biology, University Paul Sabatier Toulouse

Publications

Pré-publication, Document de travail (4)

Extracellular matrix stiffness modulates nuclear lamina organisation and sets nuclear conditions for PRC2 repression Alexia Pigeot,Martin Rey-Millet,Amal Zine El Aabidine,Antonio Trullo,Lea Costeset al. 2025 Pré-publication, Document de travail hal-05339295v1
Competition between transcription and loop extrusion modulates promoter and enhancer dynamics Angeliki Platania,Cathie Erb,Mariano Barbieri,Bastien Molcrette,Erwan Grandgirardet al. 2023 Pré-publication, Document de travail hal-04312310v1
The histone variant macroH2A1.1 regulates gene expression by direct association with their transcription start site Ludmila Recoules,Alexandre Heurteau,Flavien Raynal,Fatima Moutahir,Fabienne Bejjaniet al. 2020 Pré-publication, Document de travail hal-03037462v1
Real-time chromatin dynamics at the single gene level during transcription activation Thomas T Germier,Silvia Kocanova,Nike N Walther,Aurélien Bancaud,Haitham Ahmed H A Shabanet al. 2017 Pré-publication, Document de travail hal-01587450v1

Article dans une revue (37)

The genome in space and time comes of age Martin Rey-Millet,Kerstin Bystricky Nucleus, 2024, 15 (1), pp.2307665. ⟨10.1080/19491034.2024.2307665⟩ Article dans une revue hal-05534090v1
Enhancer-driven local 3D chromatin domain folding modulates transcription in human mammary tumor cells Silvia Kocanova,Flavien Raynal,Isabelle Goiffon,Betul Akgol Oksuz,Davide Baúet al. Life Science Alliance, 2023, 7 (2), pp.e202302154. ⟨10.26508/lsa.202302154⟩ Article dans une revue hal-04688595v1
Enhancer-driven 3D chromatin domain folding modulates transcription in human mammary tumor cells Silvia Kocanova,Flavien Raynal,Isabelle Goiffon,Betul Akgol Oksuz,Davide Baúet al. Life Science Alliance, 2023, 7 (2), pp.e202302154. ⟨10.26508/lsa.202302154⟩ Article dans une revue hal-04689503v1
Recruitment of the Histone Variant MacroH2A1 to the Pericentric Region Occurs upon Chromatin Relaxation and Is Responsible for Major Satellite Transcriptional Regulation Ludmila Recoules,Nicolas Tanguy Le Gac,Fatima Moutahir,Kerstin Bystricky,A.-C. Lavigne Cells, 2023, 12 (17), pp.2175. ⟨10.3390/cells12172175⟩ Article dans une revue hal-04260867v1
The histone variant macroH2A1.1 regulates RNA polymerase II-paused genes within defined chromatin interaction landscapes Ludmila Recoules,Alexandre Heurteau,Flavien Raynal,Nezih Karasu,Fatima Moutahiret al. Journal of Cell Science, 2022, 135 (7), pp.jcs259456. ⟨10.1242/jcs.259456⟩ Article dans une revue hal-03798057v1
ANCHOR: A Technical Approach to Monitor Single-Copy Locus Localization in Planta Anis Meschichi,Mathieu Ingouff,Claire Picart,Marie Mirouze,Sophie Dessetet al. Frontiers in Plant Science, 2021, 12, pp.677849. ⟨10.3389/fpls.2021.677849⟩ Article dans une revue hal-03313521v1
Precise measurements of chromatin diffusion dynamics by modeling using Gaussian processes Guilherme Oliveira,Attila Oravecz,Dominique Kobi,Manon Maroquenne,Kerstin Bystrickyet al. Nature Communications, 2021, 12 (1), pp.6184. ⟨10.1038/s41467-021-26466-7⟩ Article dans une revue hal-03709399v1
The Histone Variant MacroH2A1 Regulates Key Genes for Myogenic Cell Fusion in a Splice-Isoform Dependent Manner Sarah Hurtado-Bagès,Melanija Posavec Marjanovic,Vanesa Valero,Roberto Malinverni,David Corujoet al. Cells, 2020, 9 (5), pp.1109. ⟨10.3390/cells9051109⟩ Article dans une revue hal-04688893v1
Fluorescent Tagged Vaccinia Virus Genome Allows Rapid and Efficient Measurement of Oncolytic Potential and Discovery of Oncolytic Modulators Franck Gallardo,Doris Schmitt,Renée Brandely,Catherine Brua,Nathalie Silvestreet al. Biomedicines, 2020, 8 (12), pp.543. ⟨10.3390/biomedicines8120543⟩ Article dans une revue hal-03196860v1
The Histone Variant MacroH2A1 Regulates Key Genes for Myogenic Cell Fusion in a Splice-Isoform Dependent Manner Sarah Hurtado-Bagès,Melanija Posavec Marjanovic,Vanesa Valero,Roberto Malinverni,David Corujoet al. Cells, 2020, 9 (5), pp.1109. ⟨10.3390/cells9051109⟩ Article dans une revue hal-03052706v1
The Histone Variant MacroH2A1 Regulates Key Genes for Myogenic Cell Fusion in a Splice-Isoform Dependent Manner Sarah Hurtado-Bagès,Melanija Posavec Marjanovic,Vanesa Valero,Roberto Malinverni,David Corujoet al. Cells, 2020, 9 (5), pp.1109. ⟨10.3390/cells9051109⟩ Article dans une revue hal-03052322v1
The Histone Variant MacroH2A1 Regulates Key Genes for Myogenic Cell Fusion in a Splice-Isoform Dependent Manner Sarah Hurtado-Bagès,Melanija Posavec Marjanovic,Vanesa Valero,Roberto Malinverni,David Corujoet al. Cells, 2020, 9 (5), pp.1109. ⟨10.3390/cells9051109⟩ Article dans une revue hal-03026527v1
Addressing the role of centromere sites in activation of ParB proteins for partition complex assembly Sylvain Audibert,Nicolas Tanguy-Le-Gac,Jérôme Rech,Catherine Turlan,Jean-Yves Bouetet al. PLoS ONE, 2020, 15 (5), pp.e0226472. ⟨10.1371/journal.pone.0226472⟩ Article dans une revue hal-02976781v1
Rouse model with transient intramolecular contacts on a timescale of seconds recapitulates folding and fluctuation of yeast chromosomes Marius Socol,Renjie Wang,Daniel Jost,Pascal Carrivain,Cédric Vaillantet al. Nucleic Acids Research, 2019, 47 (12), pp.6195-6207. ⟨10.1093/nar/gkz374⟩ Article dans une revue hal-02276944v1
Challenges and guidelines toward 4D nucleome data and model standards Marc Marti-Renom,Geneviève Almouzni,Wendy Bickmore,Kerstin Bystricky,Giacomo Cavalliet al. Nature Genetics, 2018, 50 (10), pp.1352-1358. ⟨10.1038/s41588-018-0236-3⟩ Article dans une revue hal-01980465v1
Activation of the Notch Signaling Pathway In Vivo Elicits Changes in CSL Nuclear Dynamics Maria Gomez-Lamarca,Julia Falo-Sanjuan,Robert Stojnic,Sohaib Abdul Rehman,Leila Muresanet al. Developmental Cell, 2018, 44 (5), pp.611-623.e7. ⟨10.1016/j.devcel.2018.01.020⟩ Article dans une revue hal-02356433v1
Real-Time Imaging of a Single Gene Reveals Transcription-Initiated Local Confinement Thomas T Germier,Silvia Kocanova,Nike N Walther,Aurélien Bancaud,Haitham Ahmed H A Shabanet al. Biophysical Journal, 2017, 113 (7), pp.1383 - 1394. ⟨10.1016/j.bpj.2017.08.014⟩ Article dans une revue hal-01682625v1
Molecular and Biochemical Analysis of the Estrogenic and Proliferative Properties of Vitamin E Compounds Farid Khallouki,Philippe de Médina,Stéphanie Caze-Subra,Kerstin Bystricky,Patrick Balagueret al. Frontiers in Oncology, 2016, 5, ⟨10.3389/fonc.2015.00287⟩ Article dans une revue hal-02271824v1
Histone deacetylase 9 regulates breast cancer cell proliferation and the response to histone deacetylase inhibitors Marion Lapierre,Aurélien Linares,Mathieu Dalvai,Céline Duraffourd,Sandrine Bonnetet al. Oncotarget, 2016, 7 (15), pp.19693-708. ⟨10.18632/oncotarget.7564⟩ Article dans une revue hal-01873610v1
Differential Chromosome Conformations as Hallmarks of Cellular Identity Revealed by Mathematical Polymer Modeling Imen Lassadi,Alain Kamgoué,Isabelle Goiffon,Nicolas Tanguy-Le-Gac,Kerstin Bystricky PLoS Computational Biology, 2015, 11 (6), pp.e1004306. ⟨10.1371/journal.pcbi.1004306⟩ Article dans une revue hal-03026206v1
HDAC inhibition does not induce estrogen receptor in human triple-negative breast cancer cell lines and patient-derived xenografts Patricia De Cremoux,Mathieu Dalvai,Olivia N'Doye,Fatima Moutahir,Gaëlle Rollandet al. Breast Cancer Research and Treatment, 2015, 149 (1), pp.81-89. ⟨10.1007/s10549-014-3233-y⟩ Article dans une revue hal-03653860v1
Increased macroH2A1.1 Expression Correlates with Poor Survival of Triple-Negative Breast Cancer Patients Anne-Claire Lavigne,Magali Castells,Jérôme Mermet,Silvia Kocanova,Mathieu Dalvaiet al. PLoS ONE, 2014, 9 (6), pp.e98930. ⟨10.1371/journal.pone.0098930⟩ Article dans une revue hal-03026386v1
Increased macroH2A1.1 Expression Correlates with Poor Survival of Triple-Negative Breast Cancer Patients Anne-Claire Lavigne,Magali Castells,Jérôme Mermet,Silvia Kocanova,Mathieu Dalvaiet al. PLoS ONE, 2014, 9 (6), pp.e98930. ⟨10.1371/journal.pone.0098930⟩ Article dans une revue hal-03107782v1
Reptin and Pontin Oligomerization and Activity Are Modulated through Histone H3 N-terminal Tail Interaction Richard Queval,Christophe Papin,Mathieu Dalvai,Kerstin Bystricky,Odile Humbert Journal of Biological Chemistry, 2014, 289 (49), pp.33999--34012. ⟨10.1074/jbc.M114.576785⟩ Article dans une revue hal-04965896v1
High-throughput chromatin motion tracking in living yeast reveals the flexibility of the fiber throughout the genome Houssam Hajjoul,Julien Mathon,Hubert Ranchon,Pascal Carrivain,Isabelle Goiffonet al. Genome Research, 2013, 23 (11), pp.1829-1838. ⟨10.1101/gr.157008.113⟩ Article dans une revue hal-01053149v1
Tracking of single and multiple genomic loci in living yeast cells. Imen Lassadi,Kerstin Bystricky Methods in Molecular Biology, 2011, 745, pp.499-522. ⟨10.1007/978-1-61779-129-1_29⟩ Article dans une revue hal-00667460v1
Ligands specify estrogen receptor alpha nuclear localization and degradation. Silvia Kocanova,Mahta Mazaheri,Stéphanie Caze-Subra,Kerstin Bystricky BMC Cell Biology, 2010, 11, pp.98. ⟨10.1186/1471-2121-11-98⟩ Article dans une revue hal-00611852v1
Auraptene is an inhibitor of cholesterol esterification and a modulator of estrogen receptors. Philippe de Médina,Salvatore Genovese,Michael R. Paillasse,Mahta Mazaheri,Stéphanie Caze-Subraet al. Molecular Pharmacology, 2010, 78 (5), pp.827-36. ⟨10.1124/mol.110.065250⟩ Article dans une revue inserm-00519166v1
Cell cycle and anti-estrogen effects synergize to regulate cell proliferation and ER target gene expression. Mathieu Dalvai,Kerstin Bystricky PLoS ONE, 2010, 5 (6), pp.e11011. ⟨10.1371/journal.pone.0011011⟩ Article dans une revue hal-00611855v1
Activation of estrogen-responsive genes does not require their nuclear co-localization. Silvia Kocanova,Elizabeth A Kerr,Sehrish Rafique,Shelagh Boyle,Elad Katzet al. PLoS Genetics, 2010, 6 (4), pp.e1000922. ⟨10.1371/journal.pgen.1000922⟩ Article dans une revue hal-00611864v1
The role of histone modifications and variants in regulating gene expression in breast cancer. Mathieu Dalvai,Kerstin Bystricky Journal of Mammary Gland Biology and Neoplasia, 2010, 15 (1), pp.19-33. ⟨10.1007/s10911-010-9167-z⟩ Article dans une revue istex hal-00611848v1
The Saccharomyces cerevisiae vacuolar acid trehalase is targeted at the cell surface for its physiological function. Susu He,Kerstin Bystricky,Sebastien Leon,Jean Marie François,Jean L Parrou FEBS Journal, 2009, 276 (19), pp.5432-46. ⟨10.1111/j.1742-4658.2009.07227.x⟩ Article dans une revue hal-00493311v1
Genome duality. Silvia Kocanova,Kerstin Bystricky Genome Biology, 2009, 10 (5), pp.308. ⟨10.1186/gb-2009-10-5-308⟩ Article dans une revue hal-00611769v1
Yeast silent mating type loci form heterochromatic clusters through silencer protein-dependent long-range interactions. Adriana Miele,Kerstin Bystricky,Job Dekker PLoS Genetics, 2009, 5 (5), pp.e1000478. ⟨10.1371/journal.pgen.1000478⟩ Article dans une revue hal-00611784v1
Eliminating epigenetic barriers induces transient hormone-regulated gene expression in estrogen receptor negative breast cancer cells. L. Fleury-Ricordeau,Marie Gérus,A.-C. Lavigne,Hélène Richard-Foy,K. Bystricky Oncogene, 2008, 27 (29), pp.4075-85. ⟨10.1038/onc.2008.41⟩ Article dans une revue hal-00308948v1
Eliminating epigenetic barriers induces transient hormone-regulated gene expression in estrogen receptor negative breast cancer cells L Fleury,M Gerus,Anne-Claire Lavigne,H Richard-Foy,Kerstin Bystricky Oncogene, 2008, 27 (29), pp.4075 - 4085. ⟨10.1038/onc.2008.41⟩ Article dans une revue hal-03107835v1
Estrogen receptor alpha and the activating protein-1 complex cooperate during insulin-like growth factor-I-induced transcriptional activation of the pS2/TFF1 gene Sylvain Pierre, Raoul, Vincent Baron,Aurélie Escande,Geraldine Alberola,Kerstin Bystricky,Patrick Balagueret al. Journal of Biological Chemistry, 2007, 282 (16), pp.11732-41. ⟨10.1074/jbc.M610079200⟩ Article dans une revue hal-00308949v1

Communication dans un congrès (2)

Synthesis and cellular evaluation of new bi-specific estrogen receptor modulators and ACAT/SOAT inhibitors as anticancer agents Farid Khallouki,M Poirot,Stéphanie Caze-Subra,Kerstin Bystricky,Sandrine Silvente-Poirotet al. 12th ENOR symposium, Importance of Oxysterols in Nutrition, Cancer, and Other Degenerative Diseases, ENOR, Sep 2023, Toulouse, France Communication dans un congrès inserm-05029726v1
Design, synthesis and cellular evaluation of new bi-specific estrogen receptor modulators and ACAT inhibitors as anticancer agents Farid Khallouki,Guillaume Amouroux,Stéphanie Caze-Subra,Kerstin Bystricky,Patrick Balagueret al. 9th ENOR SYMPOSIUM, Metabolism and Oxysterols: Therapeutics for Lifelong Health, ENOR, Sep 2019, Edinbourg, Ecosse, United Kingdom Communication dans un congrès inserm-05029855v1

Chapitre d'ouvrage (3)

Analysis of Cellular EMT States Using Molecular Biology and High Resolution FISH Labeling Noémie Kempf,Fatima Moutahir,Isabelle Goiffon,Sylvain Cantaloube,Kerstin Bystrickyet al. Analysis of cellular EMT states usingmolecular biology and high resolution FISH labelling, 2179, Springer US, pp.353-383, 2021, Methods in Molecular Biology, ⟨10.1007/978-1-0716-0779-4_27⟩ Chapitre d'ouvrage hal-03026505v1
Analysis of Cellular EMT States Using Molecular Biology and High Resolution FISH Labeling Noémie Kempf,Fatima Moutahir,Isabelle Goiffon,Sylvain Cantaloube,Kerstin Bystrickyet al. Methods Mol Biol., 2179, pp.353-383, 2021, ⟨10.1007/978-1-0716-0779-4_27⟩ Chapitre d'ouvrage hal-03107762v1
Capturing Chromosome Structural Properties From Their Spatial and Temporal Fluctuations Aurélien Bancaud,Olivier Gadal,Kerstin Bystricky Epigenetics and Systems Biology, 2017, 9780128030752 Chapitre d'ouvrage hal-01682736v1

Brevet (1)

Visualisation de la position et de la dynamique de loci d'ADN dans les cellules vivantes en utilisant un nouveau groupe de petits opérateurs bactériens. K. Bystricky,F. Gallardo,D. Lane,N. Dubarry Patent n° : PCT/EP2012/055258. WO/2012/127047. 2012 Brevet hal-00789694v1