Kévin Alexandre

Publications

Article dans une revue (31)

Immune dysregulation through longitudinal lymphocyte trajectories and their clinical determinants in hospitalized COVID-19 patients José Pedro Cidade,Fabio Silvio Taccone,Luis Felipe Reyes,Laura Merson,Benjamin Lefèvreet al. Intensive Care Medicine Experimental, 2026, 14 (1), pp.14. ⟨10.1186/s40635-026-00864-x⟩ Article dans une revue (article de synthèse) hal-05501498v1
Linezolid use in post-neurosurgical central nervous system infections: A systematic review Charles Baulier,Noémie Le Dentu,Mathieu Lozouet,Yves Kam,Gaétan Kerdelhuéet al. Neurosurgical Review, 2025, 48 (1), pp.714. ⟨10.1007/s10143-025-03891-6⟩ Article dans une revue hal-05319080v1
Effect of pH on antimicrobial activity of delafloxacin against &lt;i&gt;Escherichia coli&lt;/i&gt; isogenic strains carrying diverse chromosomal and plasmid-mediated fluoroquinolone resistance mechanisms K Alexandre,Marina Murillo-Torres,Fernando Docobo-Pérez,Álvaro Pascual,Jose Manuel Rodríguez-Martínez Microbiology Spectrum, 2025, 13 (12), pp.e0233825. ⟨10.1128/spectrum.02338-25⟩ Article dans une revue hal-05352146v1
Pharmacokinetic/pharmacodynamic targets of ß-lactams associated with bacterial killing and suppression of the resistance emergence in the hollow fiber infection model: A systematic review Charles Baulier,Marion Giry,Manuel Etienne,Julien Kallout,Kévin Alexandre Journal of Global Antimicrobial Resistance, 2025, 45, pp.220 - 227. ⟨10.1016/j.jgar.2025.10.009⟩ Article dans une revue hal-05352140v1
Individual health insurance data of antibiotic delivery in previous months as a tool to predict bacterial resistance of urinary tract infection: A prospective cohort study Kévin Alexandre,André Gillibert,Sandrine Dahyot,Roland Fabre,Francis Kuhnet al. Infectious Diseases Now, 2024, 54 (6), pp.104942. ⟨10.1016/j.idnow.2024.104942⟩ Article dans une revue hal-04669488v1
Sex differences in post-acute neurological sequelae of SARS-CoV-2 and symptom resolution in adults after coronavirus disease 2019 hospitalization: an international multi-centre prospective observational study Sung-Min Cho,Lavienraj Premraj,Denise Battaglini,Jonathon Paul Fanning,Jacky Suenet al. Brain Communications, 2024, 6 (2), pp.44. ⟨10.1093/braincomms/fcae036⟩ Article dans une revue hal-04831170v1
A 52-year-old immunocompromised man with an unusual cause of infectious lung cavitary inducing acute respiratory failure Tifany Vatignez,Ludovic Lemée,Hélène Morisse-Pradier,Priscille Carvalho-Lallement,Kevin Alexandreet al. Respiratory Medicine and Research, 2024, 86 (10), pp.101101. ⟨10.1016/j.resmer.2024.101101⟩ Article dans une revue hal-05308614v1
Characteristics and outcomes of COVID-19 patients admitted to hospital with and without respiratory symptoms Barbara Wanjiru Citarella,Christiana Kartsonaki,Elsa Ibáñez-Prada,Bronner Gonçalves,Joaquin Baruchet al. Heliyon, 2024, 10 (10), pp.e29591. ⟨10.1016/j.heliyon.2024.e29591⟩ Article dans une revue hal-04831141v1
Characteristics and outcomes of COVID-19 patients admitted to hospital with and without respiratory symptoms Barbara Wanjiru Citarella,Christiana Kartsonaki,Elsa D Ibáñez-Prada,Bronner P Gonçalves,Joaquin Baruchet al. Heliyon, 2024, 10, pp.e29591. ⟨10.1016/j.heliyon.2024.e29591⟩ Article dans une revue hal-04702019v1
Are Escherichia coli causing recurrent cystitis just ordinary uropathogenic E. coli (UPEC) strains? Nicolas Vautrin,Sandrine Dahyot,Marie Leoz,François Caron,Maxime Grandet al. Virulence, 2024, 16 (1), pp.57. ⟨10.1080/21505594.2024.2444689⟩ Article dans une revue hal-04920727v1
At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods Munib Mesinovic,Xin Ci Wong,Giri Shan Rajahram,Barbara Wanjiru Citarella,Kalaiarasu Peariasamyet al. Scientific Reports, 2024, 14 (1), pp.16387. ⟨10.1038/s41598-024-63212-7⟩ Article dans une revue hal-04831133v2
Characteristics and outcomes of an international cohort of 600 000 hospitalized patients with COVID-19 Christiana Kartsonaki,J Kenneth Baillie,Noelia García Barrio,Joaquín Baruch,Abigail Beaneet al. International Journal of Epidemiology, 2023, 52 (2), pp.355-376. ⟨10.1093/ije/dyad012⟩ Article dans une revue hal-04164628v1
Long-term neurological symptoms after acute COVID-19 illness requiring hospitalization in adult patients: insights from the ISARIC-COVID-19 follow-up study Denise Battaglini,Nicole White,Lavienraj Premraj,Barbara Wanjiru Citarella,Laura Mersonet al. Journal of Neurology, 2023, 271 (1), pp.79-86. ⟨10.1007/s00415-023-12133-y⟩ Article dans une revue hal-04399136v1
Contribution of Antibiotic Susceptibility Testing and CH Typing Compared to Next-Generation Sequencing for the Diagnosis of Recurrent Urinary Tract Infections Due to Genetically Identical Escherichia coli Isolates: a Prospective Cohort Study of Cystitis in Women Nicolas Vautrin,Kévin Alexandre,Martine Pestel-Caron,Estelle Bernard,Roland Fabreet al. Microbiology Spectrum, 2023, 11 (4), ⟨10.1128/spectrum.02785-22⟩ Article dans une revue hal-05224420v1
Association of Country Income Level With the Characteristics and Outcomes of Critically Ill Patients Hospitalized With Acute Kidney Injury and COVID-19 Marina Wainstein,Nicholas Spyrison,Danyang Dai,Moji Ghadimi,Jonathan Chávez-Iñiguezet al. Kidney International Reports, 2023, 8 (8), pp.1514-1530. ⟨10.1016/j.ekir.2023.05.015⟩ Article dans une revue hal-04338529v1
Implementation of Recommendations on the Use of Corticosteroids in Severe COVID-19 Félix Camirand-Lemyre,Laura Merson,Bharath Kumar Tirupakuzhi Vijayaraghavan,Aidan Burrell,Barbara Wanjiru Citarellaet al. JAMA Network Open, 2023, 6 (12), pp.e2346502. ⟨10.1001/jamanetworkopen.2023.46502⟩ Article dans une revue hal-04372873v1
Short-Course Versus Prolonged-Course Antimicrobial Therapy in Adults With Catheter-Related Septic Thrombosis: A Propensity-Weighted Retrospective Study Marine Stoldick,Margot Vannier,Mikael Verdalle-Cazes,Manuel Etienne,Kévin Alexandre Open Forum Infectious Diseases, 2023, 10 (11), ⟨10.1093/ofid/ofad530⟩ Article dans une revue hal-04853526v1
Thrombotic and hemorrhagic complications of COVID-19 in adults hospitalized in high-income countries compared with those in adults hospitalized in low- and middle-income countries in an international registry Matthew Griffee,Patricia Bozza,Luis Felipe Reyes,Devin Eddington,Dorothea Rosenbergeret al. Research and Practice in Thrombosis and Haemostasis, 2023, 7 (5), pp.102142. ⟨10.1016/j.rpth.2023.102142⟩ Article dans une revue hal-04338492v1
Comment on: Pharmacodynamic evaluation of intermittent versus extended and continuous infusions of piperacillin/tazobactam in a hollow-fibre infection model against Klebsiella pneumoniae Marion Giry,Sacha Sarfati,Martine Pestel-Caron,Julien Wils,Fabien Lamoureuxet al. Journal of Antimicrobial Chemotherapy, 2022, ⟨10.1093/jac/dkac150⟩ Article dans une revue hal-03670777v1
Respiratory support in patients with severe COVID-19 in the International Severe Acute Respiratory and Emerging Infection (ISARIC) COVID-19 study: a prospective, multinational, observational study Luis Felipe Reyes,Srinivas Murthy,Esteban Garcia-Gallo,Laura Merson,Elsa Ibáñez-Pradaet al. Critical Care, 2022, 26 (1), pp.276. ⟨10.1186/s13054-022-04155-1⟩ Article dans une revue hal-03932306v2
ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19 Ali Abbas,Sheryl Ann Abdukahil,Nurul Najmee Abdulkadir,Ryuzo Abe,Laurent Abelet al. Scientific Data , 2022, 9 (1), pp.454. ⟨10.1038/s41597-022-01534-9⟩ Article dans une revue hal-03830494v1
Phenotypic and genotypic within-host diversity of Pseudomonas aeruginosa urinary isolates Agnès Cottalorda,Sandrine Dahyot,Anaïs Soares,Kevin Alexandre,Isabelle Zorgniottiet al. Scientific Reports, 2022, 12, ⟨10.1038/s41598-022-09234-5⟩ Article dans une revue insu-03665281v1
Increased risk of severe COVID-19 in hospitalized patients with SARS-CoV-2 Alpha variant infection: a multicentre matched cohort study Guillaume Martin-Blondel,François-Xavier Lescure,Lambert Assoumou,Charlotte Charpentier,Jean-Marc Chapplainet al. BMC Infectious Diseases, 2022, 22 (1), pp.540. ⟨10.1186/s12879-022-07508-x⟩ Article dans une revue hal-03727828v1
COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study Sheryl Ann Abdukahil,Ali Ait Hssain,Younes Ait Tamlihat,Kazali Enagnon Alidjnou,Carlos Alexandre Antunes de Britoet al. Infection, 2021, 49 (5), pp.889-905. ⟨10.1007/s15010-021-01599-5⟩ Article dans une revue hal-03273644v1
The value of open-source clinical science in pandemic response: lessons from ISARIC [Comment] Ali Abbas,Sheryl Ann Abdukahil,Nurul Najmee Abdulkadir,Ryuzo Abe,Laurent Abelet al. The Lancet Infectious Diseases, 2021, 21 (12), pp.1623-1624. ⟨10.1016/S1473-3099(21)00565-X⟩ Article dans une revue pasteur-04098113v1
Impact on disease mortality of clinical, biological, and virological characteristics at hospital admission and overtime in COVID‐19 patients Yazdan Yazdanpanah,Alpha Diallo,Christelle Paul,Noémie Mercier,Soizic Le Mestreet al. Journal of Medical Virology, 2021, 93 (4), pp.2149-2159. ⟨10.1002/jmv.26601⟩ Article dans une revue hal-04121463v1
Cardiopulmonary Exercise Testing to Assess Persistent Symptoms at 6 Months in People With COVID-19 Who Survived Hospitalization: A Pilot Study David Debeaumont,Fairuz Boujibar,Eglantine Ferrand-Devouge,Elise Artaud-Macari,Fabienne Tamionet al. Physical Therapy, 2021, 101 (6), pzab099. ⟨10.1093/ptj/pzab099⟩ Article dans une revue hal-05306279v1
Corticosteroids in patients hospitalized for COVID-19 pneumonia who require oxygen: observational comparative study using routine care data Viet-Thi Tran,Matthieu Mahévas,Firouze Bani-Sadr,Olivier Robineau,Thomas Perpointet al. Clinical Microbiology and Infection, 2021, 27 (4), pp.603-610. ⟨10.1016/j.cmi.2020.11.035⟩ Article dans une revue hal-03687923v1
Cellulitis and bacteremia after a snake bite despite antibiotic preemptive treatment: A diagnosis challenge Mathilde Réveillon-Istin,Dabor Resiere,Sandrine Dahyot,Kévin Alexandre,Hossein Mehdaouiet al. Travel Medicine and Infectious Disease, 2020, 35 (1), pp.101555. ⟨10.1016/j.tmaid.2020.101555⟩ Article dans une revue hal-05320317v1
Efficacy of a ciprofloxacin/amikacin combination against planktonic and biofilm cultures of susceptible and low-level resistant Pseudomonas aeruginosa Anaïs Soares,Kévin Alexandre,Fabien Lamoureux,Ludovic Lemée,Francois Caronet al. Journal of Antimicrobial Chemotherapy, 2019, 74 (11), pp.3252-3259. ⟨10.1093/jac/dkz355⟩ Article dans une revue hal-02343583v1
Temocillin breakpoints in pyelonephritis: evaluation in a murine model due to ESBL-producing Escherichia coli clinical isolates Kévin Alexandre,Anaïs Soares,Françoise Chau,Bruno Fantin,Francois Caronet al. Journal of Antimicrobial Chemotherapy, 2019, 74 (5), pp.1323-1326. ⟨10.1093/jac/dky569⟩ Article dans une revue hal-02372777v1

Communication dans un congrès (1)

IMPLÉMENTATION DU MODÈLE HFIM EN NORMANDIE Marion Giry,Kévin Alexandre Rencontres Normandes de Microbiologie, May 2023, Rouen (Université de Rouen Normandie), France Communication dans un congrès hal-04185170v1

Poster de conférence (18)

Efficacy of different Piperacillin-Tazobactam -Amikacin regimens against ESBL Escherichia coli in a Hollow Fiber Infection Model simulating sepsis augmented renal clearance Marion Giry,Clément Marlat,Charles Baulier,Fabien Lamoureux,Ariella Ganemet al. ECCMID, Apr 2025, Vienne, Austria Poster de conférence hal-05222678v1
In Vitro efficacy of Cefepime/Enmetazobactam against AmpC ßlactamase-producing Enterobacterales Clément Marlat,Marion Giry,Charles Baulier,Manuel Etienne,François Graveyet al. ECCMID, Apr 2025, Vienne, Austria Poster de conférence hal-05222646v1
Effect of augmented renal clearance on in vitro bactericidal activity of Cefepime-Enmetazobactam against ESBL-producing Escherichia coli evaluated via a mechanism-based modeling Marion Giry,Clément Marlat,Charles Baulier,Fabien Lamoureux,François Graveyet al. ECCMID, Apr 2025, Vienne, Austria Poster de conférence hal-05222657v1
Effect of pH on the bacteriostatic and bactericidal activities of Delafloxacin against Escherichia coli isogenic strains harboring diverse chromosomal and plasmid-mediated fluoroquinolone resistance mechanisms Kévin Alexandre,C Sauco Carballo,M Murillo-Torres,F Docobo Perez,J M Rodriguezet al. ECCMID, Apr 2025, Vienne, Austria Poster de conférence hal-05222690v1
Surdosage en ß lactamines au cours du traitement par amoxicilline ceftriaxone dans l'endocardite infectieuse à Enterococcus faecalis : épidémiologie et devenir des patients Nassim Boutouchent,Isabelle Gueit,Julien Wils,Manuel Etienne,Sandrine Dahyotet al. 24èmes Journées Nationales d'Infectiologie, Jun 2023, Grenoble, France Poster de conférence hal-04185346v1
Recurrent cystitis episodes are caused by &quot;ordinary&quot; uropathogenic Escherichia coli strains Nicolas Vautrin,Sandrine Dahyot,Marie Leoz,François Caron,Maxime Grandet al. 33rd European congress of clinical microbiology and infectious diseases (ECCMID), Apr 2023, Copenhague, Denmark Poster de conférence hal-04184212v1
In vitro activity of hydroxychloroquine in combination with antibiotics against uropathogenic Escherichia coli intracellular bacterial colonies V Pargny,N Vautrin,O Minlong,D Ribet,M Pestel-Caronet al. 33rd European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2023), Apr 2023, Copenhague, Denmark Poster de conférence hal-04184217v1
Therapeutic drug monitoring in patients with infective endocarditis treated with amoxicillin plus ceftriaxone Nassim Boutouchent,Fabien Lamoureux,Manuel Etienne,Julien Wils,Sandrine Dahyotet al. 33rd European Congress of Clinical Microbiology & Infectious Diseases (ECCMID), Apr 2023, Copenhagen, Denmark. 23, 2019 Poster de conférence hal-04184240v1
Short-Course Versus Prolonged-Course Antimicrobial Therapy in Adults With Catheter-Related Septic Thrombosis: a Propensity-Weighted Retrospective Study Marine Stoldick,Margot Vannier,Mikael Verdalles-Cazes,Manuel Etienne,Kévin Alexandre ECCMID, Apr 2023, Copenhagen, Denmark Poster de conférence hal-04184293v1
Efficacy of antimicrobial-lock therapy in catheter-related bloodstream infection C. Marlat,Julien Grosjean,T. Pressat Laffouilhere,Manuel Etienne,Kévin Alexandreet al. 33rd European Congress of Clinical Microbiology & Infectious Diseases (ECCMID), Apr 2023, Copenhagen, Denmark Poster de conférence hal-04184248v1
Place des rechutes et de l'invasion de la paroi vésicale dans la physiopathologie des cystites récidivantes à Escherichia coli Nicolas Vautrin,Kévin Alexandre,David Ribet,Sandrine Dahyot,Marie Leozet al. Journée Normande de Recherche Biomédicale (JNRB 2022), Jun 2022, Rouen, France Poster de conférence hal-03706255v1
Activité d'associations Hydroxychloroquine-Antibiotique vis-à-vis de colonies bactériennes intracellulaires d'Escherichia coli V Pargny,N Vautrin,O Minlong,D Ribet,M Pestel-Caronet al. RICAI 2022, Dec 2022, Paris, France Poster de conférence hal-04034434v1
Caractéristiques cliniques des infections ou colonisations urinaires à Pseudomonas aeruginosa A Cottalorda,S Dahyot,A Soares,K Alexandre,M Etienneet al. RICAI, Dec 2018, Paris, France Poster de conférence hal-02270974v1
Escherichia coli : caractérisation moléculaire de souches de cystites récidivantes N Vautrin,S Dahyot,R Fabre,M Etienne,M. Pestel-Caronet al. 3ème Journée Normande de Recherche Biomédicale, Sep 2018, Rouen, France. Poster de conférence hal-02268733v1
Infections ou colonisations urinaires liées à Pseudomonas aeruginosa : caractéristiques cliniques des patients A Cottalorda,S Dahyot,A Soares,K Alexandre,M Etienneet al. 3ème Journée Normande de Recherche Biomédicale, Sep 2018, Rouen, France. Poster de conférence hal-02268707v1
Cystites donnant lieu à ECBU en ville : Étude prospective de 529 cas Mathilde Réveillon-Istin,Kévin Alexandre,Roland Fabre,Valérie Delbos,Manuel Etienneet al. Journées Nationales d'Infectiologie, Jun 2018, Nantes, France Poster de conférence hal-02131944v1
Témocilline : concentration critique à 16mg/L d'après un modèle de pyélonéphrite à souches cliniques K Alexandre,A Soares,F Caron,M Etienne Journée Normande de Recherche Biomédicale, Nov 2017, Caen, France Poster de conférence hal-02266187v1
Cystites : l'antibiorésistance est très dépendante du terrain Mathilde Réveillon-Istin,Kévin Alexandre,Roland Fabre,Valérie Delbos,Manuel Etienneet al. RICAI, Dec 2017, Paris, France Poster de conférence hal-02269349v1

Thèse (1)

Evaluation expérimantale des concentrations critiques de la témocilline vis-à-vis de souches d'entérobactérales. Kévin Alexandre Médecine humaine et pathologie. Normandie Université, 2019. Français. ⟨NNT : 2019NORMR074⟩ Thèse tel-02435131v1

Mémoire d'étudiant (1)

Place de la témocilline dans le traitement probabiliste des infections urinaires communautaires Kévin Alexandre Médecine humaine et pathologie. 2017 Mémoire d'étudiant dumas-01592138v1