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Targeting RNA:protein interactions with an integrative approach leads to the identification of potent YBX1 inhibitors
Krystel El Hage
,
Nicolas Babault
,
Olek Maciejak
,
Bénédicte Desforges
,
Pierrick Craveur
et al.
Article dans une revue
hal-03955052
v1
|
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Targeting the Major Groove of the Palindromic d(GGCGCC)2 Sequence by Oligopeptide Derivatives of Anthraquinone Intercalators
Krystel El Hage
,
Giovanni Ribaudo
,
Louis Lagardère
,
Alberto Ongaro
,
Philippe H. Kahn
et al.
Article dans une revue
hal-03624169
v1
|
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YB-1 unwinds mRNA secondary structures in vitro and negatively regulates stress granule assembly in HeLa cells
Karina Budkina
,
Krystel El Hage
,
Marie-Jeanne Clément
,
Bénédicte Desforges
,
Ahmed Bouhss
et al.
Article dans une revue
hal-03333572
v1
|
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Identification of a small molecule splicing inhibitor targeting UHM domains
Asaki Kobayashi
,
Marie-Jeanne Clément
,
Pierrick Craveur
,
Krystel El Hage
,
Jean Matha Salone
et al.
Article dans une revue
hal-03354012
v1
|
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Lin28, a major translation reprogramming factor, gains access to YB-1-packaged mRNA through its cold-shock domain
Anastasiia Samsonova
,
Krystel El Hage
,
Bénédicte Desforges
,
Vandana Joshi
,
Marie-Jeanne Clément
et al.
Article dans une revue
hal-03176308
v1
|
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The cooperative binding of TDP-43 to GU-rich RNA repeats antagonizes TDP-43 aggregation
Juan Carlos Rengifo-Gonzalez
,
Krystel El Hage
,
Marie-Jeanne Clément
,
Emilie Steiner
,
Vandana Joshi
et al.
Article dans une revue
hal-03343496
v1
|
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Water Dynamics Around Proteins: T- and R-States of Hemoglobin and Melittin
Marco Pezzella
,
Krystel El Hage
,
Michiel Niesen
,
Sucheol Shin
,
Adam Willard
et al.
Article dans une revue
hal-02969027
v1
|
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Quantum-Chemistry based design of halobenzene derivatives with augmented affinities for the HIV-1 viral G4/C16 base-pair.
Perla El Darazi
,
Léa El Khoury
,
Krystel El Hage
,
Richard G. Maroun
,
Zeina Hobaika
et al.
Article dans une revue
hal-02377718
v1
|
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Spectrometric and computational studies of the binding of HIV-1 integrase inhibitors to viral DNA extremities
Léa El-Khoury
,
Krystel El Hage
,
Jean-Philip Piquemal
,
Serge Fermandjian
,
Richard G. Maroun
et al.
Article dans une revue
hal-02372493
v1
|
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A Simple Isomerization of the Purine Scaffold of a Kinase Inhibitor, Roscovitine, Affords a Four- to Seven-Fold Enhancement of Its Affinity for Four CDKs. Could This Be Traced Back to Conjugation-Induced Stiffenings/Loosenings of Rotational Barriers?
Krystel El Hage
,
Jean-Philip Piquemal
,
Nassima Oumata
,
Laurent Meijer
,
Hervé Galons
et al.
Article dans une revue
hal-02126840
v1
|
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Impact of Quadrupolar Electrostatics on Atoms Adjacent to the Sigma-Hole in Condensed-Phase Simulations
Krystel El Hage
,
Tristan Bereau
,
Sofie Jakobsen
,
Markus Meuwly
Article dans une revue
hal-02160334
v1
|
|
Sequential Proton Coupled Electron Transfer (PCET): Dynamics Observed over 8 Orders of Magnitude in Time
Luke Macaleese
,
Sylvain Hermelin
,
Krystel El Hage
,
Pierre Chouzenoux
,
Alexander Kulesza
et al.
Article dans une revue
hal-01344620
v1
|
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Extending Halogen-based Medicinal Chemistry to Proteins
Krystel El Hage
,
Vijay Pandyarajan
,
Nelson Phillips
,
Brian Smith
,
John Menting
et al.
Article dans une revue
hal-02160383
v1
|
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Approaching the double-faceted nature of the CX bond in halobenzenes with a bifunctional probe
Krystel El Hage
,
Jean-Philip Piquemal
,
Zeina Hobaika
,
Richard G. Maroun
,
Nohad Gresh
Article dans une revue
hal-02126856
v1
|
|
Could the “Janus-like” properties of the halobenzene CX bond (XCl, Br) be leveraged to enhance molecular recognition?
Krystel El Hage
,
Jean-Philip Piquemal
,
Zeina Hobaika
,
Richard G. Maroun
,
Nohad Gresh
Article dans une revue
istex
hal-02126858
v1
|
|
Substituent-Modulated Affinities of Halobenzene Derivatives to the HIV-1 Integrase Recognition Site. Analyses of the Interaction Energies by Parallel Quantum Chemical and Polarizable Molecular Mechanics
Krystel El Hage
,
Jean-Philip Piquemal
,
Zeina Hobaika
,
Richard G. Maroun
,
Nohad Gresh
Article dans une revue
hal-02126859
v1
|
|
Polarizable Molecular Mechanics Studies of Cu(I)/Zn(II) Superoxide Dismutase: Bimetallic Binding Site and Structured Waters
Nohad Gresh
,
Krystel El Hage
,
David Perahia
,
Jean-Philip Piquemal
,
C. Berthomieu
et al.
Article dans une revue
istex
hal-01081843
v1
|
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Could an anisotropic molecular mechanics/dynamics potential account for sigma hole effects in the complexes of halogenated compounds?
Krystel El Hage
,
Jean-Philip Piquemal
,
Zeina Hobaika
,
Richard G. Maroun
,
Nohad Gresh
Article dans une revue
istex
hal-02126864
v1
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