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Structural profiles of the full phagocyte NADPH oxidase unveiled by combining computational biology and experimental knowledge

Sana Aimeur , Burcu Aykac Fas , Xavier Serfaty , Hubert Santuz , Sophie Sacquin-Mora et al.

Journal of Biological Chemistry, 2024, 300 (12), pp.107943. ⟨10.1016/j.jbc.2024.107943⟩

Article dans une revue hal-04834774v1

Improved Expression of a Thermostable GH18 Bacterial Chitinase in Two Different Escherichia coli Strains and Its Potential Use in Plant Protection and Biocontrol of Phytopathogenic Fungi

Aymen Ezzine , Safa Ben Hadj Mohamed , Sofiane Bezzine , Yosra Aoudi , Mohamed Rabeh Hajlaoui et al.

Molecular Biotechnology, 2024, ⟨10.1007/s12033-023-01041-1⟩

Article dans une revue hal-04493926v1
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Role of the phospholipid binding sites, PX of p47 phox and PB region of Rac1, in the formation of the phagocyte NADPH oxidase complex NOX2

Dina Al Abyad , Xavier Serfaty , Pauline Lefrançois , Stéphane Arbault , Laura Baciou et al.

Biochimica et Biophysica Acta:Biomembranes, 2023, 1865 (7), pp.184180. ⟨10.1016/j.bbamem.2023.184180⟩

Article dans une revue hal-04129544v1

New insights in the molecular regulation of the NADPH oxidase 2 activity: Negative modulation by Poldip2

Aicha Bouraoui , Ruy Andrade Louzada , Sana Aimeur , Jehan Waeytens , Frank Wien et al.

Free Radical Biology and Medicine, 2023, 199, pp.113-125. ⟨10.1016/j.freeradbiomed.2023.02.019⟩

Article dans une revue hal-04264849v1
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Accumulation of Cytochrome b558 at the Plasma Membrane: Hallmark of Oxidative Stress in Phagocytic Cells

Stephenson Owusu , Sophie Dupre-Crochet , Tania Bizouarn , Chantal Houee Levin , Laura Baciou

International Journal of Molecular Sciences, 2022, 23 (2), pp.767. ⟨10.3390/ijms23020767⟩

Article dans une revue hal-03781870v1
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Consequences of the constitutive NOX2 activity in living cells: Cytosol acidification, apoptosis, and localized lipid peroxidation

Hana Valenta , Sophie Dupre-Crochet , Mouna Abdesselem , Tania Bizouarn , Laura Baciou et al.

Biochimica et Biophysica Acta - Molecular Cell Research, 2022, 1869 (9), pp.119276. ⟨10.1016/j.bbamcr.2022.119276⟩

Article dans une revue hal-03858717v1
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Radiation-induced reactive oxygen species partially assemble neutrophil NADPH oxidase

Stephenson B Owusu , Elodie Hudik , Céline Férard , Sophie Dupré-Crochet , Eric C D K Addison et al.

Free Radical Biology and Medicine, 2021, 164, pp.76-84. ⟨10.1016/j.freeradbiomed.2020.12.233⟩

Article dans une revue hal-03319583v1
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Mechanistic Insights on Heme-to-Heme Transmembrane Electron Transfer Within NADPH Oxydases From Atomistic Simulations

Xiaojing Wu , Jérôme Hénin , Laura Baciou , Marc Baaden , Fabien Cailliez et al.

Frontiers in Chemistry, 2021, 9, ⟨10.3389/fchem.2021.650651⟩

Article dans une revue hal-03382660v1

Cloning and heterologous expression of subtilisin SAPN, a serine alkaline protease from Melghiribacillus thermohalophilus Nari2AT in Escherichia coli and Pichia pastoris

Sondes Mechri , Nadia Zaraî Jaouadi , Khelifa Bouacem , Fawzi Allala , Aicha Bouraoui et al.

Process Biochemistry, 2021, 105, pp.27-41. ⟨10.1016/j.procbio.2021.03.020⟩

Article dans une revue (article de synthèse) hal-04669852v1
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PolDIP2, une protéine clé de la régulation du fonctionnement mitochondrial et du métabolisme cellulaire

Étienne Andjongo , Sonia Benhamouche , Aicha Bouraoui , Laura Baciou

Médecine/Sciences, 2021, 37 (1), pp.97-100. ⟨10.1051/medsci/2020263⟩

Article dans une revue hal-03858707v1
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Cloning and heterologous expression of subtilisin SAPN, a serine alkaline protease from Melghiribacillus thermohalophilus Nari2AT in Escherichia coli and Pichia pastoris

Sondes Mechri , Nadia Zaraî Jaouadi , Khelifa Bouacem , Fawzi Allala , Aicha Bouraoui et al.

Process Biochemistry, 2021, 105, pp.27-41. ⟨10.1016/j.procbio.2021.03.020⟩

Article dans une revue hal-04493950v1
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Impact of azole drugs on energetics, kinetics, and ligand migration pathways of CO photo-dissociation in bacterial flavohemoglobins

David Butcher , Myriam Moussaoui , Laura Baciou , Jaroslava Miksovska

RSC Advances, 2020, 10, pp.17930 - 17941. ⟨10.1039/d0ra02529a⟩

Article dans une revue hal-03041922v1
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Impacts of vesicular environment on Nox2 activity measurements in vitro

Xavier Serfaty , Pauline Lefrançois , Chantal Houée-Levin , Stéphane Arbault , Laura Baciou et al.

Biochimica et Biophysica Acta (BBA) - General Subjects, 2020, 1865 (1), pp.129767. ⟨10.1016/j.bbagen.2020.129767⟩

Article dans une revue hal-03041918v1

Phagocyte NADPH oxidase, oxidative stress and lipids: Anti- or pro ageing?

Laura Baciou , Rawand Masoud , Hager Souabni , Xavier Serfaty , Gilda Karimi et al.

Mechanisms of Ageing and Development, 2018, 172 (SI), pp.30-34. ⟨10.1016/j.mad.2017.11.001⟩

Article dans une revue hal-02143612v1

Quinones and nitroaromatic compounds as subversive substrates of Staphylococcus aureus flavohemoglobin

Myriam Moussaoui , Lina Misevičienė , Žilvinas Anusevičius , Audronė Marozienė , Florence Lederer et al.

Free Radical Biology and Medicine, 2018, 123, pp.107-115. ⟨10.1016/j.freeradbiomed.2018.05.071⟩

Article dans une revue istex hal-02368450v1
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The physicochemical properties of membranes correlate with the NADPH oxidase activity

Hager Souabni , Frank Wien , Tania Bizouarn , Chantal Houée-Levin , Matthieu M. Refregiers et al.

Biochimica et Biophysica Acta (BBA) - General Subjects, 2017, 1861 (1, Part B), pp.3520-3530. ⟨10.1016/j.bbagen.2016.06.028⟩

Article dans une revue hal-01566812v1

Exploring the arachidonic acid-induced structural changes in phagocyte NADPH oxidase p47phox and p67phox via thiol accessibility and SRCD spectroscopy

Tania Bizouarn , Gilda Karimi , Rawand Masoud , Hager Souabni , Paul Machillot et al.

FEBS Journal, 2016, 283 (15), pp.2896-2910. ⟨10.1111/febs.13779⟩

Article dans une revue hal-01570646v1
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Titanium Dioxide Nanoparticles Increase Superoxide Anion Production by Acting on NADPH Oxidase

Rawand Masoud , Tania Bizouarn , Sylvain Trépout , Frank Wien , Laura Baciou et al.

PLoS ONE, 2015, 10 (12), ⟨10.1371/journal.pone.0144829⟩

Article dans une revue hal-01707694v1
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Assembly of phagocyte NADPH oxidase: A concerted binding process?

Gilda Karimi , Chantal Houée-Levin , Marie Claire Dagher , Laura Baciou , Tania Bizouarn

Biochimica et Biophysica Acta (BBA) - General Subjects, 2014, 1840 (11), pp.3277-3283. ⟨10.1016/j.bbagen.2014.07.022⟩

Article dans une revue hal-04071160v1
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trans Arachidonic acid isomers inhibit NADPH-oxidase activity by direct interaction with enzyme components

H. Souabni , V. Thoma , Tania Bizouarn , C. Chatgilialoglu , A. Siafaka-Kapadai et al.

Biochimica et Biophysica Acta:Biomembranes, 2012, 1818 (9), pp.2314-2324. ⟨10.1016/j.bbamem.2012.04.018⟩

Article dans une revue hal-05331761v1

Efficient expression of the anti-AahI' scorpion toxin nanobody under a new functional form in a Pichia pastoris system.

Aymen Ezzine , Sonia M'Hirsi El Adab , Balkiss Bouhaouala-Zahar , Issam Hmila , Laura Baciou et al.

Biotechnology and Applied Biochemistry, 2012, 59 (1), pp.15-21. ⟨10.1002/bab.67⟩

Article dans une revue istex pasteur-01375137v1

Expression of functional mammal flavocytochrome b(558) in yeast: comparison with improved insect cell system.

Mariano A. Ostuni , Leila B. Lamanuzzi , Tania Bizouarn , Marie-Claire Dagher , Laura Baciou

BBA - Biochimica et Biophysica Acta, 2010, 1798 (6), pp.1179-88. ⟨10.1016/j.bbamem.2010.02.016⟩

Article dans une revue hal-00820712v1
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Modulation of the activity of the NADPH oxidase system by reactive oxygen species: influence of catalase

Mariano A. Ostuni , T. Bizouarn , L. Baciou , C. Houee-Levin

Radiation Protection Dosimetry, 2010, 143 (2-4), pp.166-171. ⟨10.1093/rpd/ncq518⟩

Article dans une revue hal-05521957v1
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Expression of functional mammal flavocytochrome b558 in yeast: Comparison with improved insect cell system

Mariano A. Ostuni , Leila B Lamanuzzi , Tania Bizouarn , Marie-Claire Dagher , Laura Baciou

Biochimica et Biophysica Acta:Biomembranes, 2010, 1798 (6), pp.1179-1188. ⟨10.1016/j.bbamem.2010.02.016⟩

Article dans une revue hal-05431596v1
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Expression of functional mammal flavocytochrome b558 in yeast: Comparison with improved insect cell system

Mariano A. Ostuni , Leila Lamanuzzi , Tania Bizouarn , Marie-Claire Dagher , Laura Baciou

Biochimica et Biophysica Acta:Biomembranes, 2010, 1798 (6), pp.1179-1188. ⟨10.1016/j.bbamem.2010.02.016⟩

Article dans une revue hal-05452317v1
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Are the fluorescent properties of the cyan fluorescent protein sensitive to conditions of oxidative stress?

Luis A.J. Alvarez , Chantal Houee Levin , Fabienne Merola , Tania Bizouarn , Hélène Pasquier et al.

Photochemistry and Photobiology, 2010, ⟨10.1111/j.1751-1097.2009.00617.x⟩

Article dans une revue hal-04058486v1

The cytosolic subunit p67phox of the NADPH-oxidase complex does not bind NADPH.

Laura Baciou , Marie Erard , Marie Claire Dagher , Tania Bizouarn

FEBS Letters, 2009, 583 (19), pp.3225-9. ⟨10.1016/j.febslet.2009.09.011⟩

Article dans une revue istex hal-00820720v1

Preliminary electrochemical studies of the flavohaemoprotein from Ralstonia eutropha entrapped in a film of methyl cellulose: Activation of the reduction of dioxygen

Pedro de Oliveira , A. Ranjbari , L. Baciou , T. Bizouarn , G. Ollesch et al.

Bioelectrochemistry, 2007, 70 (1), pp.185-191

Article dans une revue hal-00126555v1

Specific Triazine Resistance in Bacterial Reaction Centers Induced by a Single Mutation in the QA Protein Pocket. [Erratum to document cited in CA142:171460]

J.A. Spitz , V. Derrien , L. Baciou , P. Sebban

Biochemistry, 2005, 44 (8), pp.3122

Article dans une revue hal-00126536v1

Unveiling Complex Biological Mechanisms: Integrating Experimental Approaches with Artificial Intelligence

Laura Baciou

JOURNÉE SCIENTIFIQUE Thème: Stress oxydant et antioxydants: une approche scientifique moderne, Dr A. Ezzine, Jul 2024, Soukra, Tunisia

Communication dans un congrès hal-05393587v1

When Artificial Intelligence Needs to Meet Reality

Laura Baciou

11th International Conference on Oxidative Stress in Skin Biology and Medicine, Sep 2024, Andros, Greece

Communication dans un congrès hal-05393599v1

When AI Needs to Meet Reality

Laura Baciou

NYANSAPO AI SYMPOSIUM 2023, Oct 2023, Accra (Ghana), Ghana

Communication dans un congrès hal-05393620v1

Structural exploration of protein-protein interactions within Nox2 complex

Laura Baciou , Sana Zineb Aimeur

GDR NADPH Oxydase-Stress Oxydant & Club Oxydase, Nov 2023, Orsay, France

Communication dans un congrès hal-05393570v1

Simulation moléculaire du transfert d’électron transmembranaire dans NOX5

F. Cailliez , Xiaojing Wu , Jérôme Hénin , Laura Baciou , Marc Baaden et al.

3ème réunion pleinière du GDR NADPH Oxydase et Stress oxydant, Nov 2022, Aussois (France), France

Communication dans un congrès hal-04426169v1