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Discovery of new diaryl ether inhibitors against Mycobacterium tuberculosis targeting the minor portal of InhA
Mélina Chebaiki
,
Evelyne Delfourne
,
Rasoul Tamhaev
,
Saïda Danoun
,
Frédéric Rodriguez
Article dans une revue
hal-04244940v1
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The conserved yeast protein Knr4 involved in cell wall integrity is a multi-domain intrinsically disordered protein
Manon Batista
,
Ellen I.M. Donker
,
Cécile Bon
,
Myriam Guillien
,
Adriana Caisso
Article dans une revue
hal-03874437v2
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Drug screening approach against mycobacterial fatty acyl-AMP ligase FAAL32 renews the interest of the salicylanilide pharmacophore in the fight against tuberculosis
Nguyen-Hung Le
,
Patricia Constant
,
Samuel Tranier
,
Virginie Nahoum
,
Valérie Guillet
Article dans une revue
hal-03758907v1
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Fragment-Based Ligand Discovery Applied to the Mycolic Acid Methyltransferase Hma (MmaA4) from Mycobacterium tuberculosis
Romain Galy
,
Stéphanie Ballereau
,
Yves Génisson
,
Lionel Mourey
,
Jean-Christophe Plaquevent
Article dans une revue
hal-03683937v1
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Phosphopantetheinyl transferase binding and inhibition by amidino-urea and hydroxypyrimidinethione compounds
Coralie Carivenc
,
Laurent Maveyraud
,
Claire Blanger
,
Stéphanie Ballereau
,
Coralie Roy-Camille
Article dans une revue
hal-03345048v1
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Protein X-ray Crystallography and Drug Discovery
Laurent Maveyraud
,
Lionel Mourey
Article dans une revue
hal-02950589v1
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Molecular Basis for Extender Unit Specificity of Mycobacterial Polyketide Synthases
Anna D Grabowska
,
Yoann Brison
,
Laurent Maveyraud
,
Sabine Gavalda
,
Alexandre Faille
Article dans une revue
hal-03752170v2
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Structural insights into chaperone addiction of toxin-antitoxin systems
Valerie Guillet
,
Patricia Bordes
,
Cécile Bon
,
Julien Marcoux
,
Virginie Gervais
Article dans une revue
hal-02335509v1
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Occurrence and stability of hetero-hexamer associations formed by β-carboxysome CcmK shell components
Luis F Garcia-Alles
,
Katharina Root
,
Laurent Maveyraud
,
Nathalie Aubry
,
Eric Lesniewska
Article dans une revue
hal-03841381v1
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An overview on crystal structures of InhA protein: Apo-form, in complex with its natural ligands and inhibitors
Aurélien Chollet
,
Laurent Maveyraud
,
Christian Lherbet
,
Vania Bernardes-Génisson
Article dans une revue
hal-01952876v1
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Insights into Substrate Modification by Dehydratases from Type I Polyketide Synthases
Alexandre Faille
,
Sabine Gavalda
,
Nawel Slama
,
Christian Lherbet
,
Laurent Maveyraud
Article dans une revue
hal-03002100v1
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Insight into Structure-Function Relationships and Inhibition of the Fatty Acyl-AMP Ligase (FadD32) Orthologs from Mycobacteria
Valérie Guillet
,
Ségolène Galandrin
,
Laurent Maveyraud
,
Simon Ladevèze
,
Vincent Mariaule
Article dans une revue
hal-03002148v1
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Crystal structure of the enoyl-ACP reductase of Mycobacterium tuberculosis (InhA) in the apo-form and in complex with the active metabolite of isoniazid pre-formed by a biomimetic approach
Aurélien Chollet
,
Lionel Mourey
,
Christian Lherbet
,
Alexandra Delbot
,
Sylviane Julien
Article dans une revue
hal-03002973v1
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Crystallographic studies of the structured core domain of Knr4 fromSaccharomyces cerevisiae
Sylviane Julien
,
Patrick Tondl
,
Fabien Durand
,
Adilia Dagkessamanskaia
,
Herman van Tilbeurgh
Acta crystallographica Section F : Structural biology communications [2014-..], 2015, 71 (9), pp.1120 - 1124. ⟨10.1107/s2053230x15012522⟩
Article dans une revue
hal-03002962v1
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Residues Essential for Panton-Valentine Leukocidin S Component Binding to Its Cell Receptor Suggest Both Plasticity and Adaptability in Its Interaction Surface
Benoit-Joseph Laventie
,
Frédéric Guerin
,
Lionel Mourey
,
Mira y Tawk
,
Emmanuel Jover
Article dans une revue
hal-03002978v1
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Crystallization and preliminary crystallographic studies of both components of the staphylococcal LukE–LukD leukotoxin
Romain Galy
,
Fabien Bergeret
,
Daniel Keller
,
Lionel Mourey
,
Gilles Prévost
Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 2012, 68, pp.663 - 667. ⟨10.1107/s1744309112014662⟩
Article dans une revue
hal-03003049v1
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Structural reorganization of the antigen-binding groove of human CD1b for presentation of mycobacterial sulfoglycolipids
L F Garcia-Alles
,
A Collmann
,
C Versluis
,
B Lindner
,
J Guiard
Proceedings of the National Academy of Sciences of the United States of America, 2011, 108 (43), pp.17755 - 17760. ⟨10.1073/pnas.1110118108⟩
Article dans une revue
hal-03003377v1
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Crystal structure of human CD1e reveals a groove suited for lipid-exchange processes
Luis Garcia-Alles
,
Gaelle Giacometti
,
Cees Versluis
,
Laurent Maveyraud
,
Diane de Paepe
Proceedings of the National Academy of Sciences of the United States of America, 2011, 108 (32), pp.13230 - 13235. ⟨10.1073/pnas.1105627108⟩
Article dans une revue
hal-03003375v1
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Structural basis for sugar recognition, including the Tn carcinoma antigen, by the lectin SNA-II from Sambucus nigra
Laurent Maveyraud
,
Hideaki Niwa
,
Valérie Guillet
,
Dmitri I Svergun
,
Peter V Konarev
Article dans une revue
hal-03003386v1
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A covalent S-F heterodimer of leucotoxin reveals molecular plasticity of β-barrel pore-forming toxins
Pierre Roblin
,
Valérie Guillet
,
Olivier R. Joubert
,
Daniel Keller
,
Monique Erard
Article dans une revue
hal-03003397v1
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Endogenous phosphatidylcholine and a long spacer ligand stabilize the lipid-binding groove of CD1b
Luis Garcia-Alles
,
Kees Versluis
,
Laurent Maveyraud
,
Ana Tesouro Vallina
,
Sebastiano Sansano
Article dans une revue
hal-03003440v1
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6-(Hydroxyalkyl)penicillanates as Probes for Mechanisms of .BETA.-Lactamases.
Dasantila Golemi
,
Laurent Maveyraud
,
Akihiro Ishiwata
,
Samuel Tramer
,
Kazuyuki Miyashita
Article dans une revue
hal-03004369v1
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The structure of a Staphylococcus aureus leucocidin component (LukF-PV) reveals the fold of the water-soluble species of a family of transmembrane pore-forming toxins
Jean-Denis Pedelacq
,
Laurent Maveyraud
,
Gilles Prévost
,
Lamine Baba-Moussa
,
Ana González
Article dans une revue
hal-03004378v1
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Crystal structure of Escherichia coli methionyl-tRNA synthetase highlights species-specific features.
Yves Mechulam
,
Emmanuelle Schmitt
,
Laurent Maveyraud
,
Charles Zelwer
,
Osamu Nureki
Article dans une revue
hal-00841066v1
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X-ray Analysis of the NMC-A β-Lactamase at 1.64-Å Resolution, a Class A Carbapenemase with Broad Substrate Specificity
Peter Swarén
,
Laurent Maveyraud
,
Xavier Raquet
,
Stéphanie Cabantous
,
Colette Duez
Article dans une revue
hal-03004553v1
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Structural Basis for Clinical Longevity of Carbapenem Antibiotics in the Face of Challenge by the Common Class A β-Lactamases from the Antibiotic-Resistant Bacteria
Laurent Maveyraud
,
Lionel Mourey
,
Lakshmi P Kotra
,
Jean-Denis Pedelacq
,
Valérie Guillet
Article dans une revue
hal-03004592v1
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Structural Basis of Extended Spectrum TEM -Lactamases CRYSTALLOGRAPHIC, KINETIC, AND MASS SPECTROMETRIC INVESTIGATIONS OF ENZYME MUTANTS*
Laurent Maveyraud
,
Isabelle Saves
,
Odile Burlet-Schiltz
,
Peter Swarén
,
Jean-Michel Masson
Article dans une revue
hal-03004742v1
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Electrostatic analysis of TEM1 -lactamase: effect of substrate binding, steep potential gradients and consequences of site-directed mutations
Peter Swarén
,
Laurent Maveyraud
,
Valérie Guillet
,
Jean-Michel Masson
,
Lionel Mourey
Article dans une revue
hal-03004753v1
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