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Laurent Soulère

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In Silico Identification of Potential Inhibitors of the SARS-CoV-2 Main Protease among a PubChem Database of Avian Infectious Bronchitis Virus 3CLPro Inhibitors

Laurent Soulère , Thibaut Barbier , Yves Queneau
Biomolecules, 2023, 13 (6), pp.956. ⟨10.3390/biom13060956⟩
Journal articles hal-04122457v1
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Importance of the 2,6-Difluorobenzamide Motif for FtsZ Allosteric Inhibition: Insights from Conformational Analysis, Molecular Docking and Structural Modifications

Thibaut Barbier , Oana Dumitrescu , Gérard Lina , Yves Queneau , Laurent Soulère
Molecules, 2023, 28 (5), pp.2055. ⟨10.3390/molecules28052055⟩
Journal articles hal-04028136v1
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Towards More Practical Methods for the Chemical Synthesis of Thioamides Using Sulfuration Agents: A Decade Update

Qiang Zhang , Laurent Soulère , Yves Queneau
Molecules, 2023, 28 (8), pp.3527. ⟨10.3390/molecules28083527⟩
Journal articles hal-04079206v1
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Synthesis and Biological Evaluation of Benzo[b]thiophene Acylhydrazones as Antimicrobial Agents against Multidrug-Resistant Staphylococcus aureus

Thibaut Barbier , Alexia Barbry , Jérémy Magand , Cédric Badiou , Floriane Davy
Biomolecules, 2022, 12 (1), pp.131. ⟨10.3390/biom12010131⟩
Journal articles hal-03719638v1
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Synthesis of phospholipids under plausible prebiotic conditions and analogies with phospholipid biochemistry or origin of life studies

Michele Fiore , Carolina Chieffo , Augustin Lopez , Dimitri Fayolle , Johal Ruiz
Astrobiology, inPress, ⟨10.1089/ast.2021.0059⟩
Journal articles hal-03591985v1
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What is a supercoiling-sensitive gene? Insights from topoisomerase I inhibition in the Gram-negative bacterium Dickeya dadantii

Maïwenn Pineau , Shiny Martis B. , Raphaël Forquet , Jessica Baude , Camille Villard
Nucleic Acids Research, 2022, 50 (16), pp.9149-9161. ⟨10.1093/nar/gkac679⟩
Journal articles hal-03774489v1
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Structural Variations in the Central Heterocyclic Scaffold of Tripartite 2,6-Difluorobenzamides: Influence on Their Antibacterial Activity against MDR Staphylococcus aureus

Thibaut Barbier , Cédric Badiou , Floriane Davy , Yves Queneau , Oana Dumitrescu
Molecules, 2022, 27 (19), pp.6619. ⟨10.3390/molecules27196619⟩
Journal articles hal-03923036v1
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Synthesis of new 1,4‐ and 1,5‐disubstituted N ‐ethyl acetate and N ‐α‐butyro‐γ‐lactone alkylimidazole derivatives as N ‐acylhomoserine lactone analogs

Qiang Zhang , Si-Zhe Li , Yves Queneau , Laurent Soulère
Journal of Heterocyclic Chemistry, inPress, ⟨10.1002/jhet.4356⟩
Journal articles hal-03378482v1
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Heterocyclic Chemistry Applied to the Design of N-Acyl Homoserine Lactone Analogues as Bacterial Quorum Sensing Signals Mimics

Qiang Zhang , Sizhe Li , Maha Hachicha , Mohamed Boukraa , Laurent Soulère
Molecules, 2021, 26 (17), pp.5135. ⟨10.3390/molecules26175135⟩
Journal articles hal-03378442v1
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PGRP-LB: An Inside View into the Mechanism of the Amidase Reaction

Julien Orlans , Carole Vincent-Monegat , Isabelle Rahioui , Catherine Sivignon , Agata Butryn
International Journal of Molecular Sciences, 2021, 22 (9), pp.4957. ⟨10.3390/ijms22094957⟩
Journal articles hal-03237949v1

Straightforward Synthesis of Chiral Terpenoid Building Blocks by Ru-Catalyzed Enantioselective Hydrogenation

Johal Ruiz , Philippe Oger , Laurent Soulère , Florence Popowycz
Journal of Organic Chemistry, 2021, ⟨10.1021/acs.joc.1c00677⟩
Journal articles hal-03275385v1
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Docking-based virtual screening studies aiming at the covalent inhibition of SARS-CoV-2 MPro by targeting the cysteine 145

Laurent Soulère , Thibaut Barbier , Yves Queneau
Computational Biology and Chemistry, 2021, 92, pp.107463. ⟨10.1016/j.compbiolchem.2021.107463⟩
Journal articles hal-03243702v1

Computer-Assisted Conformational Analysis of Small Molecules Using VEGA ZZ, a Freely Available Software Program, as an Introduction to Molecular Modeling

Laurent Soulère
Journal of Chemical Education, 2021, 98 (8), pp.2709-2713. ⟨10.1021/acs.jchemed.1c00017⟩
Journal articles hal-04167147v1
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Esters of Glucose-2-Phosphate: Occurrence and Chemistry

Zhang Qiang , Si-Zhe Li , Mohammed Ahmar , Laurent Soulère , Yves Queneau
Molecules, 2020, 25 (12), pp.2829. ⟨10.3390/molecules25122829⟩
Journal articles hal-02883902v1
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CKD Increases Carbonylation of HDL and Is Associated with Impaired Antiaggregant Properties

Nans Florens , Catherine Calzada , Sandrine Lemoine , Marie Michèle Boulet , Nicolas Guillot
Journal of the American Society of Nephrology, 2020, 31 (7), pp.1462-1477. ⟨10.1681/ASN.2019111205⟩
Journal articles hal-03046430v1
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Biological Evaluation and Docking Studies of New Carbamate, Thiocarbamate, and Hydrazide Analogues of Acyl Homoserine Lactones as Vibrio fischeri-Quorum Sensing Modulators

Zhang Qiang , Yves Queneau , Laurent Soulère
Biomolecules, 2020, 10 (3), pp.455. ⟨10.3390/biom10030455⟩
Journal articles hal-02883805v1
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(2R)- and (2S)- 2-hydroxy Hexanoyl and Octanoyl-l-Homoserine Lactones: new highly potent Quorum Sensing modulators with opposite activities

Qiang Zhang , Erwann Jeanneau , Yves Queneau , Laurent Soulère
Bioorganic Chemistry, 2020, pp.104307. ⟨10.1016/j.bioorg.2020.104307⟩
Journal articles hal-02952061v1
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Conformational and docking studies of acyl homoserine lactones as a robust method to investigate bioactive conformations

Laurent Soulère , Yves Queneau
Computational Biology and Chemistry, 2019, 79, pp.48-54. ⟨10.1016/j.compbiolchem.2019.01.006⟩
Journal articles hal-02110869v1
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Synthesis of a non-natural glucose-2-phosphate ester able to dupe the acc system of Agrobacterium fabrum

Si-Zhe Li , Armelle Vigouroux , Mohammed Ahmar , Abbas El Sahili , Laurent Soulere
Organic & Biomolecular Chemistry, 2019, 17 (5), pp.1090--1096. ⟨10.1039/c8ob03086c⟩
Journal articles hal-02173130v1

Lifestyle of the biotroph Agrobacterium tumefaciens in the ecological niche constructed on its host plant

Almudena Gonzalez-Mula , Julien Lang , Catherine Grandclément , Delphine Naquin , Mohammed Ahmar
New Phytologist, 2018, 219 (1), pp.350-362. ⟨10.1111/nph.15164⟩
Journal articles hal-02110550v1

Identification of novel antilipogenic agents targeting fatty acid biosynthesis through structure-based virtual screening

Laurent Soulère , Pascaline M. Alix , Marine L. Croze , Christophe Soulage
Chemical Biology and Drug Design, 2018, 92 (1), pp.1366-1372. ⟨10.1111/cbdd.13202⟩
Journal articles hal-01847387v1
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Skeletal muscle insulin resistance is induced by 4-hydroxy-2-hexenal, a by-product of n-3 fatty acid peroxidation

Christophe Soulage , Laura Sardón Puig , Laurent Soulère , Bader Zarrouki , Michel Guichardant
Diabetologia, 2018, 61 (3), pp.688-699. ⟨10.1007/s00125-017-4528-4⟩
Journal articles hal-02110460v1

Influence of the d/l configuration of N-acyl-homoserine lactones (AHLs) and analogues on their Lux-R dependent quorum sensing activity

Si-Zhe Li , Rui Xu , Mohammed Ahmar , Catherine Goux-Henry , Yves Queneau
Bioorganic Chemistry, 2018, 77, pp.215-222. ⟨10.1016/j.bioorg.2018.01.005⟩
Journal articles hal-02110506v1
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2-Substituted Aniline as a Simple Scaffold for LuxR-Regulated QS Modulation

S. Li , J. Wawrzyniak , Y. Queneau , L. Soulère
Molecules, 2017, 22 (12), pp.E2090. ⟨10.3390/molecules22122090⟩
Journal articles hal-02001353v1

Quorum Sensing Inhibitor Activities of Celecoxib Derivatives in Pseudomonas aeruginosa

Seyhan Ulusoy , Sevil Senkardes , Inci Coskun , Gulgun Bosgelmez-T|naz , Laurent Soulère
Letters in Drug Design & Discovery, 2017, 14 (5), pp.613-618. ⟨10.2174/1570180814666161121120719⟩
Journal articles hal-02193031v1

Liquid crystalline glycosteroids and acyl steroid glycosides (ASG)

Zonglong Yang , Rui Xu , Fahima Ali-Rachedi , Stéphane Chambert , Nuno Xavier
Liquid Crystals, 2017, pp.1-19. ⟨10.1080/02678292.2017.1346211⟩
Journal articles hal-02193065v1

Exploring docking methods for virtual screening: application to the identification of neuraminidase and Ftsz potential inhibitors

Laurent Soulère , Christophe Soulage
Molecular Simulation, 2017, 43 (8), pp.656-663. ⟨10.1080/08927022.2017.1290234⟩
Journal articles hal-01600438v1

α-Eleostearic acid-containing triglycerides for a continuous assay to determine lipase sn -1 and sn -3 regio-preference

Meddy El Alaoui , Laurent Soulère , Alexandre Noiriel , Yves Queneau , Abdelkarim Abousalham
Chemistry and Physics of Lipids, 2017, 206, pp.43-52. ⟨10.1016/j.chemphyslip.2017.06.005⟩
Journal articles hal-04167239v1
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Insights into the Quorum Sensing Regulon of the Acidophilic Acidithiobacillus ferrooxidans Revealed by Transcriptomic in the Presence of an Acyl Homoserine Lactone Superagonist Analog

Sigde Mamani , Danielle Moinier , Yann Denis , L. Soulère , Y. Queneau
Frontiers in Microbiology, 2016, 7, pp.1365. ⟨10.3389/fmicb.2016.01365⟩
Journal articles hal-01440758v1
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A continuous spectrophotometric assay that distinguishes between phospholipase A1 and A2 activities

Meddy El Alaoui , L. Soulere , A. Noiriel , F. Popowycz , A. Khatib
Journal of Lipid Research, 2016, 57 (8), pp.1589-1597. ⟨10.1194/jlr.D065961⟩
Journal articles hal-01477286v1
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A Pyranose-2-Phosphate Motif Is Responsible for Both Antibiotic Import and Quorum-Sensing Regulation in Agrobacterium tumefaciens

Abbas El Sahili , Si-Zhe Li , Julien Lang , Cornelia Virus , Sara Planamente
PLoS Pathogens, 2015, 11 (8), pp.e1005071. ⟨10.1371/journal.ppat.1005071⟩
Journal articles hal-01430779v1
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Glycoxidized HDL, HDL enriched with oxidized phospholipids and HDL from diabetic patients inhibit platelet function

Quang Huy Lê , Meddy El Alaoui , Evelyne Véricel , Bérénice Ségrestin , Laurent Soulère
Journal of Clinical Endocrinology and Metabolism, 2015, 100 (5), pp.1-10. ⟨10.1210/jc.2014-4214⟩
Journal articles inserm-01134619v1

A convenient method for phosphorylation using trially phosphate

S.L. Li , M. Ahmar , Y. Queneau , L. Soulère
Tetrahedron Letters, 2015, 56 (32), pp.4694-4696. ⟨10.1016/j.tetlet.2015.06.030⟩
Journal articles hal-01478940v1

Development of a high-throughput assay for measuring phospholipase A activity using synthetic 1,2-a-eleostearoyl-sn-glycero-3-phosphocholine coated on microtiter plates.

Meddy El Alauoui , Alexandre Noiriel , Laurent Soulère , Lucie Grand , Yves Queneau
Analytical Chemistry, 2014, 86 (21), pp.10576-83. ⟨10.1021/ac502096v⟩
Journal articles hal-01141494v1

A new route towards fimbrolide analogues : importance of the exomethylene motif in LuxR dependent quorum sensing inhibition

Mohamad Sabbah , Maud Bernollin , Alain Doutheau , Laurent Soulère , Yves Queneau
MedChemComm, 2013, 4 (2), pp.363-366. ⟨10.1039/c2md20298k⟩
Journal articles hal-01146328v1
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N,N'-alkylated Imidazolium-derivatives act as quorum-sensing inhibitors targeting the Pectobacterium atrosepticum-induced symptoms on potato tubers.

Yannick Raoul Des Essarts , Mohamad Sabbah , Arnaud Comte , Laurent Soulère , Yves Queneau
International Journal of Molecular Sciences, 2013, 14 (10), pp.19976-19986. ⟨10.3390/ijms141019976⟩
Journal articles hal-00919246v1
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At a supra-physiological concentration, human sexual hormones act as quorum-sensing inhibitors.

Amélie Beury-Cirou , Mélanie Tannières , Corinne Minard , Laurent Soulère , Tsiry Rasamiravaka
PLoS ONE, 2013, 8 (12), pp.e83564. ⟨10.1371/journal.pone.0083564⟩
Journal articles hal-00949341v1

AHL signaling molecules with a large acyl chain enhance biofilm formation on sulfur and metal sulfides by the bioleaching bacterium Acidithiobacillus ferrooxidans.

Alex González , Sören Bellenberg , Sigde Mamani , Lina Ruiz , Alex Echeverría
Applied Microbiology and Biotechnology, 2013, 97 (8), pp.3729-37. ⟨10.1007/s00253-012-4229-3⟩
Journal articles hal-00919253v1

The lipid peroxidation by-product 4-hydroxy-2-Nonenal (4-HNE) induces insulin resistance in skeletal

J. Pillon N. , L. Croze M. , E. Vella R. , L. Soulère , M. Lagarde
Endocrinology, 2012, 153 (5), pp.2099-2111. ⟨10.1210/en.2011-1957⟩
Journal articles hal-01555917v1

Synthesis and biological evaluation of new N-acyl-homoserine-lactone analogues, based on triazole and tetrazole scaffolds, acting as LuxR-dependent quorum sensing modulators.

Mohamad Sabbah , Fanny Fontaine , Lucie Grand , Mohamed Boukraa , Mohamed L Efrit
Bioorganic and Medicinal Chemistry, 2012, 20 (15), pp.4727-36. ⟨10.1016/j.bmc.2012.06.007⟩
Journal articles hal-00919262v1

Mechanisms and synthetic modulators of AHL-dependent gene regulation.

Ann M Stevens , Y. Queneau , L. Soulère , Susanne von Bodman , A. Doutheau
Chemical Reviews, 2011, 111 (1), pp.4-27. ⟨10.1021/cr100064s⟩
Journal articles hal-00695865v1

Structural and Functional Changes in Human Insulin Induced by the Lipid Peroxidation Byproducts 4-Hydroxy-2-nonenal and 4-Hydroxy-2-hexenal

Nicolas Pillon , Roxane E. Vella , Laurent Soulère , Michel Becchi , Michel Lagarde
Chemical Research in Toxicology, 2011, 24 (5), pp.752 - 762. ⟨10.1021/tx200084d⟩
Journal articles hal-02650408v1

AHL-dependent quorum sensing inhibition: synthesis and biological evaluation of α-(N-alkyl-carboxamide)-γ-butyrolactones and α-(N-alkyl-sulfonamide)-γ-butyrolactones.

Mohamed Boukraa , Mohamad Sabbah , Laurent Soulère , Mohamed L El Efrit , Yves Queneau
Bioorganic and Medicinal Chemistry Letters, 2011, 21 (22), pp.6876-9. ⟨10.1016/j.bmcl.2011.09.010⟩
Journal articles hal-00695861v1

LuxR dependent quorum sensing inhibition by N,N'-disubstituted imidazolium salts.

Mohamad Sabbah , Laurent Soulère , Sylvie Reverchon , Y. Queneau , Alain Doutheau
Bioorganic and Medicinal Chemistry, 2011, 19 (16), pp.4868-75. ⟨10.1016/j.bmc.2011.06.075⟩
Journal articles hal-00695863v1

Quantitative structure-activity relationship for 4-hydroxy-2-alkenal induced cytotoxicity in L6 muscle cells

Nicolas J Pillon , Laurent Soulère , Roxane E Vella , Marine Croze , Bertrand R Caré
Chemico-Biological Interactions, 2010, 188 (1), pp.171-80. ⟨10.1016/j.cbi.2010.06.015⟩
Journal articles hal-00759515v1

LuxR-dependent quorum sensing: computer aided discovery of new inhibitors structurally unrelated to N-acylhomoserine lactones.

Laurent Soulère , Mohamad Sabbah , Fanny Fontaine , Yves Queneau , Alain Doutheau
Bioorganic and Medicinal Chemistry Letters, 2010, 20 (15), pp.4355-8. ⟨10.1016/j.bmcl.2010.06.081⟩
Journal articles hal-00695871v1
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Marine natural meroterpenes: synthesis and antiproliferative activity

Annabel Simon-Levert , Christophe Menniti , Laurent Soulère , Anne-Marie Genevière , Chantal Barthomeuf
Marine drugs, 2010, 8 (2), pp.347-358. ⟨10.3390/md8020347⟩
Journal articles hal-02190465v1

Rational design, solid phase synthesis and evaluation of cationic ferrocenoyl peptide bioconjugates as potential antioxidant enzyme mimics

Laurent Soulère , Julien Bernard
Bioorganic and Medicinal Chemistry Letters, 2009, 19 (4), pp.1173-1176. ⟨10.1016/j.bmcl.2008.12.084⟩
Journal articles hal-00374569v1

Toward Docking-Based Virtual Screening for Discovering Antitubulin Agents by Targeting Taxane and Colchicine Binding Sites

Laurent Soulère
ChemMedChem, 2009, 4 (2), pp.161-163. ⟨10.1002/cmdc.200800319⟩
Journal articles hal-04167250v1

N-Acyl-3-amino-5H-furanone derivatives as new inhibitors of LuxR-dependent quorum sensing: Synthesis, biological evaluation and binding mode study

J. Estephane , J. Dauvergne , L. Soulere , S. Reverchon , Y. Queneau
Bioorganic and Medicinal Chemistry Letters, 2008, 18 (15), pp.4321-4
Journal articles hal-01997033v1

Molecular insights into quorum sensing in Acidithiobacillus ferrooxidans bacteria via molecular modelling of the transcriptional regulator AfeR and of the binding mode of long-chain acyl homoserine lactones

Laurent Soulère , Nicolas Guiliani , Yves Queneau , Carlos Jerez , Alain Doutheau
Journal of Molecular Modeling, 2008, 14 (7), pp.599-606. ⟨10.1007/s00894-008-0315-y⟩
Journal articles hal-04167257v1

AHL communication is a widespread phenomenon in biomining bacteria and seems to be involved in mineral-adhesion efficiency

Lina María Ruiz , Susana Valenzuela , Matias Castro , Alex Gonzalez , Marine Frezza
Hydrometallurgy, 2008, 94 (1-4), pp.133-137. ⟨10.1016/j.hydromet.2008.05.028⟩
Journal articles hal-04167264v1

Synthetic homoserine lactone-derived sulfonylureas as inhibitors of Vibrio fischeri quorum sensing regulator

M. Frezza , L. Soulere , S. Reverchon , N. Guiliani , C. Jerez
Bioorganic and Medicinal Chemistry, 2008, 16 (7), pp.3550-6. ⟨10.1016/j.bmc.2008.02.023⟩
Journal articles hal-01997035v1

Bis-(O)-acetylated derivative of 4,5-dihydroxy-2,3-pentanedione (DPD): a convenient stable precursor of quorum sensing autoinducer AI-2

M. Frezza , L. Soulere , D. Balestrino , Y. Queneau , C. Forestier
Biorg.Med.Chem.Lett., 2007, 17, pp.1428-1431
Journal articles hal-00139413v1

An expeditious synthesis of 4-hydroxy-2(E)-nonenal (4-HNE), its dimethyl acetal and of related compounds

Laurent Soulère , Yves Queneau , Alain Doutheau
Chemistry and Physics of Lipids, 2007, 150 (2), pp.239-243. ⟨10.1016/j.chemphyslip.2007.07.003⟩
Journal articles hal-04167188v1

Ac2-DPD, the bis-(O)-acetylated derivative of 4,5-dihydroxy-2,3-pentanedione (DPD) is a convenient stable precursor of bacterial quorum sensing autoinducer AI-2.

Marine Frezza , Laurent Soulère , Damien Balestrino , Michel Gohar , Christian Deshayes
Bioorganic and Medicinal Chemistry Letters, 2007, 17 (5), pp.1428-31. ⟨10.1016/j.bmcl.2006.11.076⟩
Journal articles hal-00164190v1

Exploring the active site of acyl homoserine lactones-dependent transcriptional regulators with bacterial quorum sensing modulators using molecular mechanics and docking studies

Laurent Soulère , Marine Frezza , Yves Queneau , Alain Doutheau
Journal of Molecular Graphics and Modelling, 2007, 26 (2), pp.581-590. ⟨10.1016/j.jmgm.2007.04.004⟩
Journal articles hal-04167213v1

Synthesis and biological evaluation of the trifluoromethyl analog of (4S)-4,5-dihydroxy-2,3-pentanedione (DPD)

M. Frezza , D. Balestrino , L. Soulère , S. Reverchon-Pescheux , Y. Queneau
European Journal of Organic Chemistry, 2006, pp.4731-4736
Journal articles hal-00144011v1

Conjugated linoleic acid, unlike other unsaturated fatty acids, strongly induces glutathione synthesis without any lipoperoxidation

J.-P. Steghens , K. Arab , A. Rossary , L. Soulère
British Journal of Nutrition, 2006, 96 (96), pp.811-819
Journal articles hal-00144012v1

Synthesis and biological evaluation of homoserine lactone derived ureas as antagonists of bacterial quorum sensing

M. Frezza , S. Castang , J. Estephane , L. Soulere , C. Deshayes
Bioorganic and Medicinal Chemistry, 2006, 14 (14), pp.4781-91
Journal articles hal-01997034v1

A Baylis–Hillman/ozonolysis route towards (±) 4,5-dihydroxy-2,3-pentanedione (DPD) and analogues

Marine Frezza , Laurent Soulère , Yves Queneau , Alain Doutheau
Tetrahedron Letters, 2005, 46 (38), pp.6495-6498. ⟨10.1016/j.tetlet.2005.07.102⟩
Journal articles hal-04167707v1

Using binding competitors on albumin to promote the removal of protein-bound uremic toxins in hemodialysis: proof of concept and screening of candidates

Nans Florens , Yi Dan , Laurent Soulère , Laurent Juillard , Christophe Soulage
Annual Meeting of French Society of Pharmacology and Therapeutics, and INSERM Clinical Research Centers (CIC) Meeting, Jun 2019, Lyon, France. Wiley, Fundamental and Clinical Pharmacology, 33, 106 p., 2019, Abstracts of the Annual Meeting of French Society of Pharmacology and Therapeutics, and INSERM Clinical Research Centers (CIC) Meeting
Conference poster hal-02737249v1

A Continuous and Sensitive Spectrophotometric Assay for Lipase and Phospholipase A Activities using α-Eleostearic Acid-containing Substrates

Meddy El Alaoui , Laurent Soulère , Alexandre Noiriel , Priscila Sutto-Ortiz , Lucie Grand
Lipases and phospholipases, Methods and, Protocols. G. Sandoval, Ed. Methods in Molecular Biology, Springer, pp.119-128, 2018
Book sections hal-02285369v1

Carbohydrate steroid hybrid architectures : the viewpoint of amphiphilicity and self-organisation

Zhuo Yang , R. Xu , S. Chambert , L. Soulère , M. Ahmar
A.Pilar RAUTER, Thisbe K LINDHORST and Yves QUENEAU. Specialist Periodical Reports, Carbohydrate Chemistry, Chemical and Biological Approaches,, 4, pp.274-312, 2017, ⟨10.1039/9781782626657-00274⟩
Book sections hal-01477305v1