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Synthesis and Biological Evaluation of Itraconazole Derivatives: Design in an Old Scaffold
Shuai Zhong
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Apollonia Kalamatianou
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Gonzalo Scalese
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Cillian O’beirne
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Marta Redrado
et al.
Article dans une revue
hal-05211856v1
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Pharmacophore-guided optimization of the hit compound CTN1122 in the design of promising imidazo[1,2- a ]pyrazine derivatives targeting the casein kinase 1 for antileishmanial therapy
Lhana Tisseur
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Cédric Logé
,
Sandrine Cojean
,
Khadidiatou Gassama
,
Lilian Karcher
et al.
Article dans une revue
hal-05173262v1
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Investigating the C2 Modulation of the Imidazo[1,2‐ a ]pyrazine‐Based Hit Compound CTN1122: Synthesis, in vitro Antileishmanial Activity, Cytotoxicity and Casein Kinase 1 Inhibition
Lhana Tisseur
,
Sandrine Cojean
,
Khadidiatou Gassama
,
Cédric Logé
,
Fabrice Pagniez
et al.
Article dans une revue
hal-05181232v1
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Synthesis of New Dihydropyrimidine-2-Thione Derivatives and Their Antibacterial Screening
Ambeu-Loko N’ta Christelle Mélissa
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Camara Mahama
,
Coulibaly Souleymane
,
Ouattara Logopho Hyacinthe
,
Stéphanie Kra
et al.
Article dans une revue
hal-05086170v1
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Potassium 6-Oxo-7,13,16,22-tetraazatetracyclo[12.6.2.18,12.017,21]tricosa-1(20),8(23),9,11,14,16,18,21-octaen-2-yne-15-carboxylate
Camille Blouet
,
Stéphanie Letast
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Thomas Robert
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Stéphane Bach
,
Noël Pinaud
et al.
Article dans une revue
hal-04805282v1
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Exosomes as New Biomarkers and Drug Delivery Tools for the Prevention and Treatment of Various Diseases: Current Perspectives
Qi Liu
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Shiying Li
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Amandine Dupuy
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Hoa Le Mai
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Nicolas Sailliet
et al.
Article dans une revue
hal-03825290v2
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Tetraspanins: useful multifunction proteins for the possible design and development of small-molecule therapeutic tools
Jean-Michel Robert
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Nathalie Gisèle Amoussou
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Hubert Le Mai
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Cédric Logé
,
Sophie Brouard
Article dans une revue
hal-03795952v1
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Dibenzofuran Derivatives Inspired from Cercosporamide as Dual Inhibitors of Pim and CLK1 Kinases
Viet Hung Dao
,
Isabelle Ourliac-Garnier
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Cédric Logé
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Florence Mccarthy
,
Stéphane Bach
et al.
Article dans une revue
hal-03428747v1
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Untargeted Metabolomics Approach for the Discovery of Environment-Related Pyran-2-Ones Chemodiversity in a Marine-Sourced Penicillium restrictum
Van-Tuyen Le
,
Samuel Bertrand
,
Thibaut Robiou Du Pont
,
Fabrice Fleury
,
Nathalie Caroff
et al.
Article dans une revue
hal-03825219v2
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New Quinoxaline Derivatives as Dual Pim-1/2 Kinase Inhibitors: Design, Synthesis and Biological Evaluation
Bruno Oyallon
,
Marie Brachet-Botineau
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Cédric Logé
,
Thomas Robert
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Stéphane Bach
et al.
Article dans une revue
inserm-03272339v1
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New azole antifungals with a fused triazinone scaffold
David Montoir
,
Rémi Guillon
,
Sophie Gazzola
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Isabelle Ourliac-Garnier
,
Kossi Efouako Soklou
et al.
Article dans une revue
hal-03412473v1
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4-cholesten-3-one decreases breast cancer cell viability and alters membrane raft-localized EGFR expression by reducing lipogenesis and enhancing LXR-dependent cholesterol transporters
Josiane Elia
,
Delphine Carbonnelle
,
Cédric Logé
,
Lucie Ory
,
Jean-Michel Huvelin
et al.
Article dans une revue
hal-04041192v2
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Precise genome editing using a CRISPR-Cas9 method highlights the role of CoERG11 amino acid substitutions in azole resistance in Candida orthopsilosis
Florent Morio
,
Lisa Lombardi
,
Ulrike Binder
,
Cédric Logé
,
Estelle Robert
et al.
Article dans une revue
hal-03827474v1
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Structure-based design of novel quinoxaline-2-carboxylic acids and analogues as Pim-1 inhibitors
Bruno Oyallon
,
Marie Brachet-Botineau
,
Cédric Logé
,
Pascal Bonnet
,
Mohamed Souab
et al.
Article dans une revue
hal-03408667v1
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Activation of EGFR by small compounds through coupling the generation of hydrogen peroxide to stable dimerization of Cu/Zn SOD1
Vehary Sakanyan
,
Philippe Hulin
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Rodolphe Alves de Sousa
,
Viviane Silva
,
Artur Hambardzumyan
et al.
Article dans une revue
hal-03652537v1
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Synthesis and molecular modelling studies of 8-arylpyrido[3',2':4,5thieno[3,2-d]pyrimidin-4-amines as multitarget Ser/Thr kinases inhibitors
Yvonnick Loidreau
,
Emmanuel Deau
,
Pascal Marchand
,
Marie-Renée Nourrisson
,
Cédric Logé
et al.
Article dans une revue
hal-01135195v1
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Development of new highly potent imidazo[1,2-b]pyridazines targeting Toxoplasma gondii calcium-dependent protein kinase 1
Espérance Moine
,
Isabelle Dimier-Poisson
,
Cécile Enguehard-Gueiffier
,
Cédric Logé
,
Mélanie Pénichon
et al.
Article dans une revue
istex
hal-02389861v1
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Discovery of (7-aryl-1,5-naphthyridin-2-yl)ureas as dual inhibitors of ERK2 and Aurora B kinases with antiproliferative activity against cancer cells
Julien Defaux
,
Maud Antoine
,
Cédric Logé
,
Marc Le Borgne
,
Tilmann Schuster
et al.
Article dans une revue
hal-01683305v1
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Screening and discovery of nitro-benzoxadiazole compounds activating epidermal growth factor receptor (EGFR) in cancer cells
Vehary Sakanyan
,
Marie Angelini
,
Mickael Le Béchec
,
Michèle Françoise Lecocq
,
Florence Benaiteau
et al.
Article dans une revue
hal-01136283v1
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Synthesis of new pyridazino[4,5-b]indol-4-ones and pyridazin-3(2H)-one analogs as DYRK1A inhibitors
Amélie Bruel
,
Romain Beneteau
,
Mylène Chabanne
,
Olivier Lozach
,
Rémy Le Guevel
et al.
Article dans une revue
hal-01086026v1
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Discovery of a Novel Broad-Spectrum Antifungal Agent Derived from Albaconazole
Rémi Guillon
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Fabrice Pagniez
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Carine Picot
,
Damien Hédou
,
Alain Tonnerre
et al.
Article dans une revue
hal-01015468v1
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Novel synthesis of angular thiazolo[5,4-f] and [4,5-h]quinazolines, preparation of their linear thiazolo[4,5-g] and [5,4-g]quinazoline analogs
Damien Hédou
,
Rémi Guillon
,
Charlotte Lecointe
,
Cédric Logé
,
Elizabeth Chosson
et al.
Article dans une revue
istex
hal-01015586v1
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Synthesis and biological evaluation of new 5-benzylated 4-oxo-3,4-dihydro-5Hpyridazino[4,5-b]indoles as PI3Ka inhibitors.
A. Bruel
,
Cedric Logé
,
M.-L. de Tauzia
,
M. Ravache
,
Ronan Le Guével
et al.
European Journal of Medicinal Chemistry, 2012, 57, pp.225-233
Article dans une revue
hal-00764872v1
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Study of N1-alkylation of indoles from the reaction of 2(or 3)-aminoindole-3-(or 2)carbonitriles with DMF-dialkylacetals
Yvonnick Loidreau
,
Sigismund Melissen
,
Vincent Levacher
,
Cédric Logé
,
Jérôme Graton
et al.
Article dans une revue
hal-00997070v1
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Design, Synthesis, and in vitro Antifungal Activity of 1-[(4-Substituted-benzyl)methylamino]-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ols
Rémi Guillon
,
Fabrice Pagniez
,
Francis Giraud
,
Damien Crépin
,
Carine Picot
et al.
Article dans une revue
istex
hal-01689176v1
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Prostaglandins antagonistically control Bax activation during apoptosis
Lisenn Lalier
,
Pierre-François Cartron
,
Christophe Olivier
,
Cedric Logé
,
Gwenola Bougras
et al.
Article dans une revue
hal-00587969v1
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Synthesis and in vitro antifungal evaluation of 2-(2,4-difluorophenyl)-1-[(1 H -indol-3-ylmethyl)methylamino]-3-(1 H -1,2,4-triazol-1-yl)propan-2-ols
Rémi Guillon
,
Cédric Logé
,
Fabrice Pagniez
,
Véronique Ferchaud-Roucher
,
Muriel Duflos
et al.
Article dans une revue
hal-04792103v1
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Screening for amino acid substitutions in the Candida albicans Erg11 protein of azole-susceptible and azole-resistant clinical isolates: new substitutions and a review of the literature
Florent Morio
,
Cédric Logé
,
Bernard Besse
,
Christophe Hennequin
,
Patrice Le Pape
Article dans une revue
istex
hal-03830187v1
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Design of new antifungal agents: synthesis and evaluation of 1-[(1H-indol-5-ylmethyl)amino]-2-phenyl-3-(1H-1,2,4-triazol-1-yl)propan-2-ols
Rémi Guillon
,
Francis Giraud
,
Cédric Logé
,
Marc Le Borgne
,
Carine Picot
et al.
Article dans une revue
istex
hal-01689189v1
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Synthesis and structure–activity relationships of 2-phenyl-1-[(pyridinyl- and piperidinylmethyl)amino]-3-(1H-1,2,4-triazol-1-yl)propan-2-ols as antifungal agents
Francis Giraud
,
Rémi Guillon
,
Cédric Logé
,
Fabrice Pagniez
,
Carine Picot
et al.
Article dans une revue
istex
hal-01689192v1
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Design, synthesis and evaluation of 3-(imidazol- 1-ylmethyl)indoles as antileishmanial agents. Part II
Francis Giraud
,
Cédric Logé
,
Fabrice Pagniez
,
Damien Crépin
,
Sophie Barres
et al.
Article dans une revue
hal-01689191v1
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Synthesis of 3,5-bis(2-indolyl)pyridine and 3-[(2-indolyl)-5-phenyl]pyridine derivatives as CDK inhibitors and cytotoxic agents
Ulrich Jacquemard
,
Nathalie Dias
,
Amélie Lansiaux
,
Christian Bailly
,
Cédric Logé
et al.
Article dans une revue
istex
hal-04451556v1
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Design, synthesis, and evaluation of 1-(N-benzylamino)-2-phenyl-3-(1H-1,2,4-triazol-1-yl)propan-2-ols as antifungal agents
Francis Giraud
,
Cédric Logé
,
Fabrice Pagniez
,
Damien Crépin
,
Patrice Le Pape
et al.
Article dans une revue
istex
hal-01689196v1
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|
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Docking Study of Ligands into the Colchicine Binding Site of Tubulin
Amaury Farce
,
Cedric Loge
,
Sebastien Gallet
,
Nicolas Lebegue
,
Pascal Carato
et al.
Article dans une revue
hal-04451109v1
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Novel 9-oxo-thiazolo[5,4-f]quinazoline-2-carbonitrile derivatives as dual cyclin-dependent kinase 1 (CDK1)/glycogen synthase kinase-3 (GSK-3) inhibitors: Synthesis, biological evaluation and molecular modeling studies
Cédric Logé
,
Alexandra Testard
,
Valérie Thiéry
,
Olivier Lozach
,
Mélina Blairvacq
et al.
Article dans une revue
istex
hal-02357774v1
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A 3D-QSAR CoMSIA study on 3-azolylmethylindoles as anti-leishmanial agents
Francis Giraud
,
Cédric Logé
,
Marc Le Borgne
,
Fabrice Pagniez
,
Young Min Na
et al.
Article dans une revue
hal-01689291v1
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Thiazolo[5,4-f]quinazolin-9-ones, inhibitors of glycogen synthase kinase-3
Alexandra Testard
,
Cédric Logé
,
Benoît Léger
,
Jean-Michel Robert
,
Olivier Lozach
et al.
Article dans une revue
istex
hal-02357746v1
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|
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Three-dimensional model of cytochrome P450 human aromatase
Cédric Logé
,
Marc Le Borgne
,
Pascal Marchand
,
Jean-Michel Robert
,
Guillaume Le Baut
et al.
Article dans une revue
hal-01689233v1
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