Loic Hamon

Publications

Article dans une revue (45)

RNA and the RNA-binding protein FUS act in concert to prevent TDP-43 spatial segregation Clément Demongin,Samuel Tranier,Vandana Joshi,Léa Ceschi,Bénédicte Desforgeset al. Journal of Biological Chemistry, 2024, pp.105716. ⟨10.1016/j.jbc.2024.105716⟩ Article dans une revue hal-04455540v1
FUS RRM regulates poly(ADP-ribose) levels after transcriptional arrest and PARP-1 activation on DNA damage Evgeniya Mamontova,Marie-Jeanne Clément,Maria Sukhanova,Vandana Joshi,Ahmed Bouhsset al. Cell Reports, 2023, 42 (10), pp.113199. ⟨10.1016/j.celrep.2023.113199⟩ Article dans une revue hal-04231448v1
FUS fibrillation occurs through a nucleation-based process below the critical concentration required for liquid–liquid phase separation Emilie Bertrand,Clément Demongin,Ioana Dobra,Juan-Carlos Rengifo-Gonzalez,Anastasia S Singatulinaet al. Scientific Reports, 2023, 13 (1), pp.7772. ⟨10.1038/s41598-023-34558-1⟩ Article dans une revue hal-04231423v1
YB-1 Structure/function relationship in the packaging of mRNPs and consequences for translation regulation and stress granule assembly in cells Loic Hamon,Karina Budkina,David Pastre Biochemistry (mosc.), 2022 Article dans une revue hal-04583907v1
YB-1 unwinds mRNA secondary structures in vitro and negatively regulates stress granule assembly in HeLa cells Karina Budkina,Krystel El Hage,Marie-Jeanne Clément,Bénédicte Desforges,Ahmed Bouhsset al. Nucleic Acids Research, 2021, 49 (17), pp.10061-10081. ⟨10.1093/nar/gkab748⟩ Article dans une revue hal-03333572v1
Lin28, a major translation reprogramming factor, gains access to YB-1-packaged mRNA through its cold-shock domain Anastasiia Samsonova,Krystel El Hage,Bénédicte Desforges,Vandana Joshi,Marie-Jeanne Clémentet al. Communications Biology, 2021, 4 (1), pp.359. ⟨10.1038/s42003-021-01862-3⟩ Article dans une revue hal-03176308v1
ITSN1 regulates SAM68 solubility through SH3 domain interactions with SAM68 proline-rich motifs S. Pankivskyi,D. Pastré,E. Steiner,V. Joshi,A. Rynditchet al. Cellular and Molecular Life Sciences, 2021, 78, pp.1745-1763. ⟨10.1007/s00018-020-03610-y⟩ Article dans une revue hal-02968869v1
Regulation of Poly(ADP-Ribose) Polymerase 1 Activity by Y-Box-Binding Protein 1 Konstantin Naumenko,Mariya Sukhanova,Loic Hamon,Tatyana Kurgina,Elizaveta Alemasovaet al. Biomolecules, 2020, 10 (9), pp.1325. ⟨10.3390/biom10091325⟩ Article dans une revue hal-02968966v1
Inhibition of Transcription Induces Phosphorylation of YB-1 at Ser102 and Its Accumulation in the Nucleus Dmitry Kretov,Daria Mordovkina,Irina Eliseeva,Dmitry Lyabin,Dmitry Polyakovet al. Cells, 2020, 9 (1), pp.104. ⟨10.3390/cells9010104⟩ Article dans une revue hal-02968925v1
YB-1, an abundant core mRNA-binding protein, has the capacity to form an RNA nucleoprotein filament: a structural analysis Dmitry Kretov,Marie-Jeanne Clément,Guillaume Lambert,Dominique Durand,Dmitry Lyabinet al. Nucleic Acids Research, 2019, 47 (6), pp.3127-3141. ⟨10.1093/nar/gky1303⟩ Article dans une revue hal-02114790v1
A Single-Molecule Atomic Force Microscopy Study of PARP1 and PARP2 Recognition of Base Excision Repair DNA Intermediates Maria Sukhanova,Loic Hamon,Mikhail Kutuzov,Vandana Joshi,Sanae Abrakhiet al. Journal of Molecular Biology, 2019, 431 (15), pp.2655-2673. ⟨10.1016/j.jmb.2019.05.028⟩ Article dans une revue hal-02165889v1
PARP-1 Activation Directs FUS to DNA Damage Sites to Form PARG-Reversible Compartments Enriched in Damaged DNA Anastasia Singatulina,Loic Hamon,Maria Sukhanova,Bénédicte Desforges,Vandana Joshiet al. Cell Reports, 2019, 27 (6), pp.1809-1821. ⟨10.1016/j.celrep.2019.04.031⟩ Article dans une revue hal-02167709v1
Microtubules as platforms for probing liquid–liquid phase separation in cells – application to RNA-binding proteins Alexandre Maucuer,Bénédicte Desforges,Vandana Joshi,Mirela Boca,Dmitry Kretovet al. Journal of Cell Science, 2018, 131 (11), pp.jcs214692. ⟨10.1242/jcs.214692⟩ Article dans une revue hal-02166855v1
Relation Between Stress Granules and Cytoplasmic Protein Aggregates Linked to Neurodegenerative Diseases Ioana Dobra,Serhii Pankivskyi,Anastasiia Samsonova,David Pastre,Loic Hamon Current Neurology and Neuroscience Reports, 2018, 18 (12), pp.107. ⟨10.1007/s11910-018-0914-7⟩ Article dans une revue hal-02167725v1
Vectofusin-1, a potent peptidic enhancer of viral gene transfer forms pH-dependent α-helical nanofibrils, concentrating viral particles Louic Vermeer,Loic Hamon,Alicia Schirer,Michel Schoup,Jérémie Cosetteet al. Acta Biomaterialia, 2017, 64, pp.259-268. ⟨10.1016/j.actbio.2017.10.009⟩ Article dans une revue hal-02174366v1
Nanoscale Analysis Reveals the Maturation of Neurodegeneration-Associated Protein Aggregates Sanae Abrakhi,Dmitry Kretov,Bénédicte Desforges,Ioana Dobra,Ahmed Bouhsset al. ACS Nano, 2017, 11 (7), pp.7189-7200. ⟨10.1021/acsnano.7b03071⟩ Article dans une revue hal-02173623v1
Role of tau in the spatial organization of axonal microtubules: keeping parallel microtubules evenly distributed despite macromolecular crowding Alix Méphon-Gaspard,Mirela Boca,Catherine Pioche-Durieu,Bénédicte Desforges,Andrea Burgoet al. Cellular and Molecular Life Sciences, 2016, 73 (19), pp.3745-3760. ⟨10.1007/s00018-016-2216-z⟩ Article dans une revue hal-02183396v1
Polyamine signal through gap junctions : A key regulator of proliferation and gap-junction organization in mammalian tissues ? Loic Hamon,Philippe Savarin,David Pastre BioEssays, 2016, 38 (6), pp.498-507. ⟨10.1002/bies.201500195⟩ Article dans une revue istex hal-02174559v1
Single molecule detection of PARP1 and PARP2 interaction with DNA strand breaks and their poly(ADP-ribosyl)ation using high-resolution AFM imaging Maria Sukhanova,Sanae Abrakhi,Vandana Joshi,David Pastre,Mikhail Kutuzovet al. Nucleic Acids Research, 2016, 44 (6), pp.e60-e60. ⟨10.1093/nar/gkv1476⟩ Article dans une revue hal-02183571v1
mRNA and DNA selection via protein multimerization: YB-1 as a case study Dmitry Kretov,Patrick A. Curmi,Loic Hamon,Sanae Abrakhi,Bénédicte Desforgeset al. Nucleic Acids Research, 2015, 43 (19), pp.9457-9473. ⟨10.1093/nar/gkv822⟩ Article dans une revue hal-02183823v1
Free mRNA in excess upon polysome dissociation is a scaffold for protein multimerization to form stress granules Ouissame Bounedjah,Bénédicte Desforges,Ting-Di Wu,Catherine Pioche-Durieu,Sergio Marcoet al. Nucleic Acids Research, 2014, 42 (13), pp.8678-8691. ⟨10.1093/nar/gku582⟩ Article dans une revue hal-02292175v1
Structural Basis for the Association of MAP6 Protein with Microtubules and Its Regulation by Calmodulin Julien Lefèvre,Philippe Savarin,Pierre Gans,Loïc Hamon,Marie-Jeanne Clémentet al. Journal of Biological Chemistry, 2013, 288 (34), pp.24910-24922. ⟨10.1074/jbc.M113.457267⟩ Article dans une revue inserm-00858655v1
Detection of Single DNA Molecule Hybridization on a Surface by Atomic Force Microscopy David Pastre,Vandana Joshi,Patrick Curmi,Loic Hamon Small, 2013, 9 (21), pp.3630-3638. ⟨10.1002/smll.201300546⟩ Article dans une revue istex hal-02291850v1
An intercellular polyamine transfer via gap junctions regulates proliferation and response to stress in epithelial cells Bénédicte Desforges,Patrick Curmi,Ouissame Bounedjah,Samir Nakib,Loic Hamonet al. Molecular Biology of the Cell, 2013, 24 (10), pp.1505-1613. ⟨10.1091/mbc.E12-10-0729⟩ Article dans une revue hal-02292186v1
Effect of the multifunctional proteins RPA, YB-1, and XPC repair factor on AP site cleavage by DNA glycosylase NEIL1 Pavel Pestryakov,Dmitry Zharkov,Inga Grin,Elizaveta Fomina,Ekaterina Kimet al. Journal of Molecular Recognition, 2012, 25 (4), pp.224-233. ⟨10.1002/jmr.2182⟩ Article dans une revue istex hal-02292246v1
Macromolecular Crowding Regulates Assembly of mRNA Stress Granules after Osmotic Stress Ouissame Bounedjah,Loic Hamon,Philippe Savarin,Bénédicte Desforges,Patrick Curmiet al. Journal of Biological Chemistry, 2012, 287 (4), pp.2446-2458. ⟨10.1074/jbc.M111.292748⟩ Article dans une revue hal-02292253v1
Gap junctions favor normal rat kidney epithelial cell adaptation to chronic hypertonicity Bénédicte Desforges,Philippe Savarin,Ouissame Bounedjah,Stephanie Delga,Loic Hamonet al. American Journal of Physiology - Cell Physiology, 2011, 301 (3), pp.C705-C716. ⟨10.1152/ajpcell.00128.2011⟩ Article dans une revue hal-02292290v1
Rapid Assembly and Collective Behavior of Microtubule Bundles in the Presence of Polyamines Loic Hamon,Philippe Savarin,Patrick a. Curmi,David Pastre Biophysical Journal, 2011, 101 (1), pp.205-216. ⟨10.1016/j.bpj.2011.05.022⟩ Article dans une revue hal-02292262v1
Specific DNA−Protein Interactions on Mica Investigated by Atomic Force Microscopy David Pastré,Loic Hamon,Isabelle Sorel,Eric Le Cam,Patrick Curmiet al. Langmuir, 2010, 26 (4), pp.2618-2623. ⟨10.1021/la902727b⟩ Article dans une revue hal-02293295v1
A Central Role for Polyamines in Microtubule Assembly in Cells Philippe Savarin,Aurélie Barbet,Stephanie Delga,Vandana Joshi,Loic Hamonet al. Biochemical Journal, 2010, 430 (1), pp.151-159. ⟨10.1042/BJ20091811⟩ Article dans une revue hal-00506521v1
Role of Microtubules in Stress Granule Assembly Konstantin G. Chernov,Aurélie Barbet,Loic Hamon,Lev Ovchinnikov,Patrick Curmiet al. Journal of Biological Chemistry, 2009, 284 (52), pp.36569-36580. ⟨10.1074/jbc.M109.042879⟩ Article dans une revue hal-02295275v1
The Stathmin-Derived I19L Peptide Interacts with FtsZ and Alters Its Bundling Marie-Jeanne Clément,Boï-Trinh Kuoch,Tâp Ha-Duong,Vandana Joshi,Loic Hamonet al. Biochemistry, 2009, 48 (41), pp.9734-9744. ⟨10.1021/bi900556a⟩ Article dans une revue hal-02295213v1
Mica Surface Promotes the Assembly of Cytoskeletal Proteins Loic Hamon,Dulal Panda,Philippe Savarin,Vandana Joshi,Johann Bernhardet al. Langmuir, 2009, 25 (6), pp.3331-3335. ⟨10.1021/la8035743⟩ Article dans une revue hal-02294800v1
Polyamine sharing between tubulin dimers favours microtubule nucleation and elongation via facilitated diffusion Alain Mechulam,Konstantin G. Chernov,Elodie Mucher,Loic Hamon,Patrick A. Curmiet al. PLoS Computational Biology, 2009, 5 (1), pp.e1000255. ⟨10.1371/journal.pcbi.1000255⟩ Article dans une revue inserm-00705780v1
Atomic force microscopy reveals binding of mRNA to microtubules mediated by two major mRNP proteins YB-1 and PABP Konstantin G. Chernov,Patrick Curmi,Loic Hamon,Alain Mechulam,Lev Ovchinnikovet al. FEBS Letters, 2008, 582 (19), pp.2875-2881. ⟨10.1016/j.febslet.2008.07.019⟩ Article dans une revue hal-02295333v1
High-resolution AFM imaging of single-stranded DNA-binding (SSB) protein--DNA complexes L. Hamon,D. Pastré,P. Dupaigne,C. Breton,E. Camet al. Nucleic Acids Research, 2007, 35 (8), pp.e58-e58. ⟨10.1093/nar/gkm147⟩ Article dans une revue hal-02295472v1
Atomic Force Microscopy Imaging of DNA under Macromolecular Crowding Conditions David Pastre,Loic Hamon,Alain Mechulam,Isabelle Sorel,Sonia Baconnaiset al. Biomacromolecules, 2007, 8 (12), pp.3712-3717. ⟨10.1021/bm700856u⟩ Article dans une revue hal-02295397v1
A new approach to DNA bending by polyamines and its implication in DNA condensation David Pastre,Olivier Piétrement,Fabrice Landousy,Loic Hamon,Isabelle Sorelet al. European Biophysics Journal, 2006, 35 (3), pp.214-223. ⟨10.1007/s00249-005-0025-7⟩ Article dans une revue istex hal-03065301v1
Anionic Polyelectrolyte Adsorption on Mica Mediated by Multivalent Cations: A Solution to DNA Imaging by Atomic Force Microscopy under High Ionic Strengths David Pastre,Loic Hamon,Fabrice Landousy,Isabelle Sorel,Marie-Odile Davidet al. Langmuir, 2006, 22 (15), pp.6651-6660. ⟨10.1021/la053387y⟩ Article dans une revue istex hal-03065293v1
The EcoRI−DNA Complex as a Model for Investigating Protein−DNA Interactions by Atomic Force Microscopy Isabelle Sorel,Olivier Piétrement,Loic Hamon,Sonia Baconnais,Eric Le Camet al. Biochemistry, 2006, 45 (49), pp.14675-14682. ⟨10.1021/bi060293u⟩ Article dans une revue istex hal-03065288v1
Studying the effect of a charged surface on the interaction of bleomycin with DNA using an atomic force microscope Olivier Piétrement,David Pastre,Fabrice Landousy,Marie-Odile David,Stéphane Fusilet al. European Biophysics Journal, 2005, 34 (3), pp.200-207. ⟨10.1007/s00249-004-0443-y⟩ Article dans une revue istex hal-03065310v1
Thickness dependence of the glass transition temperature in thin films of partially miscible polymer blends L. Hamon,Y. Grohens,Y. Holl Langmuir, 2003, 19 (24), pp.10399-10402. ⟨10.1021/la0351461⟩ Article dans une revue hal-00188278v1
Reversible Binding of DNA on NiCl 2 -Treated Mica by Varying the Ionic Strength Olivier Piétrement,David Pastre,Stéphane Fusil,Josette Jeusset,Marie-Odile Davidet al. Langmuir, 2003, 19 (7), pp.2536-2539. ⟨10.1021/la026942u⟩ Article dans une revue istex hal-03065317v1
Adsorption of DNA to Mica Mediated by Divalent Counterions: A Theoretical and Experimental Study David Pastre,Olivier Piétrement,Stéphane Fusil,Fabrice Landousy,Josette Jeussetet al. Biophysical Journal, 2003, 85 (4), pp.2507-2518. ⟨10.1016/s0006-3495(03)74673-6⟩ Article dans une revue hal-03065312v1
Some relevant parameters affecting the glass transition of supported ultra-thin polymer films Y. Grohens,L. Hamon,A. Soldera,Y. Holl European Physical Journal E: Soft matter and biological physics, 2002, 8 (2), pp.217-224. ⟨10.1140/epje/i2001-10088-4⟩ Article dans une revue hal-05127895v1