Lorenzo Sala Chargé de Recherche Classe Normale @ INRAE

Publications

Article dans une revue (22)

Eye2Heart: A reduced mathematical model bridging cardiovascular and ocular hemodynamics Lorenzo Sala,Mohamed Zaid,Faith Hughes,Marcela Szopos,Virginia H Huxleyet al. Mathematical Biosciences and Engineering, 2026, 23 (2), pp.421 - 448. ⟨10.3934/mbe.2026017⟩ Article dans une revue hal-05448434v1
Mathematical Modeling and Artificial Intelligence to Explore Connections Between Glaucoma and the Gut Microbiome Madeline C Rocks,Priyanka Bhatnagar,Alice Verticchio Vercellin,Lorenzo Sala,Brent Sieskyet al. Medicina, 2025, 61 (2), pp.343. ⟨10.3390/medicina61020343⟩ Article dans une revue hal-04957107v1
Surrogate modeling of interactions in microbial communities through Physics-Informed Neural Networks. Paguiel Javan Hossie,Béatrice Laroche,Thibault Malou,Lucas Perrin,Thomas Saigreet al. ESAIM: Proceedings and Surveys, 2025, 81, pp.104-122. ⟨10.1051/proc/202581104⟩ Article dans une revue hal-04440736v3
A comparative analysis of metamodels for lumped cardiovascular models, and pipeline for sensitivity analysis, parameter estimation, and uncertainty quantification John M Hanna,Pavlos Varsos,Jérôme Kowalski,Lorenzo Sala,Roel Meiburget al. Computers in Biology and Medicine, 2025, 193, pp.110381. ⟨10.1016/j.compbiomed.2025.110381⟩ Article dans une revue hal-04829481v1
Derivation and validation of compartment models: implications for dynamic imaging Jérôme Kowalski,Lorenzo Sala,Dirk Drasdo,Irene Vignon-Clementel IEEE Transactions on Medical Imaging, In press, ⟨10.1109/TMI.2025.3630705⟩ Article dans une revue hal-05350568v1
The ocular mathematical virtual simulator: A validated multiscale model for hemodynamics and biomechanics in the human eye Lorenzo Sala,Christophe Prud'Homme,Giovanna Guidoboni,Marcela Szopos,Alon Harris International Journal for Numerical Methods in Biomedical Engineering, 2024, 40 (2), pp.e3791. ⟨10.1002/cnm.3791⟩ Article dans une revue hal-04300796v1
Analysis of Waveform Parameters in the Retinal Vasculature via Mathematical Modeling and Data Analytics Methods Lorenzo Sala,Kendall Lyons,Giovanna Guidoboni,Alon Harris,Marcela Szoposet al. La Matematica, 2024, 3 (4), pp.1297-1319. ⟨10.1007/s44007-024-00137-7⟩ Article dans une revue hal-04869910v1
A mechanistic modelling approach of the host–microbiota interactions to investigate beneficial symbiotic resilience in the human gut Marie Haghebaert,Béatrice Laroche,Lorenzo Sala,Stanislas Mondot,Joël Doré Journal of the Royal Society Interface, 2024, 21 (215), ⟨10.1098/rsif.2023.0756⟩ Article dans une revue hal-04623171v1
Sensitivity Analysis of a Mathematical Model Simulating the Post-Hepatectomy Hemodynamics Response Lorenzo Sala,Nicolas Golse,Alexandre Joosten,Eric Vibert,Irene Vignon-Clementel Annals of Biomedical Engineering, 2023, ⟨10.1007/s10439-022-03098-6⟩ Article dans une revue hal-03839072v1
Cardiovascular sex-differences: insights via physiology-based modeling and potential for noninvasive sensing via ballistocardiography Mohamed Zaid,Lorenzo Sala,Laurel Despins,David Heise,Mihail Popescuet al. Frontiers in Cardiovascular Medicine, 2023, 10, ⟨10.3389/fcvm.2023.1215958⟩ Article dans une revue hal-04230796v1
A HDG Method for Elliptic Problems with Integral Boundary Condition: Theory and Applications Silvia Bertoluzza,Giovanna Guidoboni,Romain Hild,Daniele Prada,Christophe Prud'Hommeet al. Journal of Scientific Computing, 2023, 95 (1), pp.6. ⟨10.1007/s10915-023-02109-5⟩ Article dans une revue hal-04073316v1
Mechanism-Driven Modeling to Aid Non-invasive Monitoring of Cardiac Function via Ballistocardiography Mohamed Zaid,Lorenzo Sala,Jan Ivey,Darla Tharp,Christina Muelleret al. Frontiers in Medical Technology, 2022, 4, ⟨10.3389/fmedt.2022.788264⟩ Article dans une revue hal-03919153v1
How environment affects active particle swarms: a case study Pierre Degond,Angelika Manhart,Sara Merino-Aceituno,Diane Peurichard,Lorenzo Sala Royal Society Open Science, 2022, 9, pp.220791. ⟨10.1098/rsos.220791⟩ Article dans une revue hal-03684115v1
Combining physiology-based modeling and evolutionary algorithms for personalized, noninvasive cardiovascular assessment based on electrocardiography and ballistocardiography Nicholas Mattia Marazzi,Giovanna Guidoboni,Mohamed Zaid,Lorenzo Sala,Laurel Despinset al. Frontiers in Physiology, 2021 Article dans une revue hal-03474363v1
Uncertainty propagation and sensitivity analysis: results from the Ocular Mathematical Virtual Simulator Christophe Prud'Homme,Lorenzo Sala,Marcela Szopos Mathematical Biosciences and Engineering, 2021, Volume 18 (Issue 3), pp.2010-2032. ⟨10.3934/mbe.2021105⟩ Article dans une revue hal-03123856v1
Neurodegenerative Disorders of the Eye and of the Brain: A Perspective on Their Fluid-Dynamical Connections and the Potential of Mechanism-Driven Modeling Giovanna Guidoboni,Riccardo Sacco,Marcela Szopos,Lorenzo Sala,Alice Chandra Verticchio Vercellinet al. Frontiers in Neuroscience, 2020, 14, ⟨10.3389/fnins.2020.566428⟩ Article dans une revue hal-03122851v1
Cardiovascular function and ballistocardiogram: a relationship interpreted via mathematical modeling Giovanna Guidoboni,Lorenzo Sala,Moein Enayati,Riccardo Sacco,Marcela Szoposet al. IEEE Transactions on Biomedical Engineering, 2019, ⟨10.1109/TBME.2019.2897952⟩ Article dans une revue hal-02278848v1
A THEORETICAL STUDY OF AQUEOUS HUMOR SECRETION BASED ON A CONTINUUM MODEL COUPLING ELECTROCHEMICAL AND FLUID-DYNAMICAL TRANSMEMBRANE MECHANISMS Lorenzo Sala,Aurelio Giancarlo Mauri,Riccardo Sacco,Dario Messenio,Giovanna Guidoboniet al. Communications in Applied Mathematics and Computational Science, 2019, 14 (1), pp.65-103. ⟨10.2140/camcos.2019.14.65⟩ Article dans une revue hal-02278844v1
Multiscale modeling of ocular physiology Lorenzo Sala,Riccardo Sacco,Giovanna Guidoboni Journal for Modeling in Ophthalmology, 2018, 2 (1), pp.12-18 Article dans une revue hal-02278863v1
Ocular mathematical virtual simulator: A hemodynamical and biomechanical study towards clinical applications Lorenzo Sala,Christophe Prud'Homme,Giovanna Guidoboni,Marcela Szopos Journal of Coupled Systems and Multiscale Dynamics, 2018, 6 (3), pp.241-247. ⟨10.1166/jcsmd.2018.1165⟩ Article dans une revue hal-02114295v1
Towards a full model for ocular biomechanics, fluid dynamics, and hemodynamics Lorenzo Sala,Christophe Prud'Homme,Marcela Szopos,Giovanna Guidoboni Journal for Modeling in Ophthalmology, 2018, 2, pp.7-13 Article dans une revue hal-02278854v1
Electro-fluid dynamics of aqueous humor production: simulations and new directions. Aurelio Giancarlo Mauri,Lorenzo Sala,Paolo Airoldi,Giovanni Novielli,Riccardo Saccoet al. Journal for Modeling in Ophthalmology, 2016, 1 (2), pp.48-58 Article dans une revue hal-01479238v1

Communication dans un congrès (20)

Hybrid Inference for Microbial Community Models: Physics-Informed Neural Networks for Parameter Estimation in Generalized Lotka-Volterra System Lorenzo Sala 2025 Workshop on Modeling, Optimization, and Control in Biomedicine, Aug 2025, Frankfurt, Germany Communication dans un congrès hal-05269905v1
Physics-Informed Neural Networks for Generalized Lotka-Volterra models: towards parameter estimation in microbial communities Lorenzo Sala SMAI 2025 - 12ème Biennale Française des Mathématiques Appliquées et Industrielles, Jun 2025, Carcans-Maubuisson (Gironde), France Communication dans un congrès hal-05269906v1
Brain Grid Application To High-Grade Gliomas: An Innovative System To Define Tumor Location And Invasiveness Umberto Aldo Arcidiacono,Alessandro Falanga,Joao Marcos Silva Sousa,Markus Fahlström,Ekaterina Tomilinaet al. EANS 2025 - European Association of Neurosurgical Societies Congress, Oct 2025, Vienna, Austria. pp.105357, ⟨10.1016/j.bas.2025.105357⟩ Communication dans un congrès hal-05350672v1
Physics-informed neural networks for data-integrated modeling of microbial interactions Lorenzo Sala DSABNS 2025 - 16th Dynamical Systems applied on Biology and Natural Sciences, Jan 2025, Napoli, Italy Communication dans un congrès hal-05269904v1
First steps towards a gut digital twin: mechanistic modelling of host–microbiota interactions to explore symbiotic resilience Lorenzo Sala CMSB 2024 - 22rd International Conference on Computational Methods in Systems Biology, Sep 2024, Pisa, Italy Communication dans un congrès hal-05269902v1
A new geometric and hemodynamic approach to understand post-operative portal thrombosis development based on in-silico modeling A. Facque,W. Liu,Lorenzo Sala,I. Vignon-Clementel,N. Golse IHPBA 2024 - 16th World Congress of the International Hepato-Pancreato-Biliary Association, May 2024, Cape Town, South Africa. pp.S28, ⟨10.1016/j.hpb.2024.03.052⟩ Communication dans un congrès hal-04869969v1
Global Sensitivity Analysis of a Hemodynamic Digital Twin in Post-Hepatectomy Liver Failure Lorenzo Sala UQ 2024 - SIAM Conference on Uncertainty Quantification, Feb 2024, Trieste, Italy Communication dans un congrès hal-05269899v1
Sex-specific differences in ophthalmic and central retinal artery velocity: A cardiovascular and retinal analysis Mohamed Zaid,Alon Harris,Lorenzo Sala,Caleb Hendrick,Brent A Sieskyet al. ARVO 2024 - annual meeting, May 2024, Seattle, United States. pp.1255 Communication dans un congrès hal-04870026v1
Modelling the Gut Microbiota: Towards a Digital Twin Lorenzo Sala Journées Nutrition et Ecosystèmes Microbiens 2024, Apr 2024, Paris, France Communication dans un congrès hal-05269896v1
Understanding Gut Microbiota Dynamics: Enhancing Generalized Smoothing Algorithm Efficiency with Data-Driven Neural Networks Lorenzo Sala Journée thématique SPE NUM sur les approches hybrides IA - Systèmes dynamiques, Dec 2024, Montpellier, France Communication dans un congrès hal-05269903v1
Relationship Between Blood Velocity in the Central Retinal Artery and Cardiac Systolic Function: a Theoretical Study Mohamed Zaid,Alon Harris,Lorenzo Sala,Marcela Szopos,Sergey Lapinet al. Investigative Ophthalmology & Visual Science, ARVO, Apr 2023, New Orleans, LA, United States Communication dans un congrès hal-04191612v1
Personalized Noninvasive Cardiovascular Monitoring via Ballistocardiography, Physiology-Based Modeling and Evolutionary Algorithm Mohamed Zaid,Nicholas Mattia Marazzi,Lorenzo Sala,Salman Ahmad,Laurel Despinset al. Math 2 Product (M2P) Emerging Technologies in Computational Science for Industry, Sustainability and Innovation, May 2023, Taormina, Italy Communication dans un congrès hal-04192070v1
Analysis of the Contribution of Cardiovascular Compartments to the Ballistocardiogram Signal Using Mathematical Modeling Mohamed Zaid,Raul Invernizzi,Lorenzo Sala,Laurel A. Despins,Mihail Popescuet al. Computing in Cardiology, 2023, Atlanta (GA), United States. ⟨10.22489/cinc.2023.406⟩ Communication dans un congrès hal-04275292v1
Understanding Organ Vascular Behavior Through their Architecture Jerome Kowalski,Lorenzo Sala,Dirk Drasdo,Irene Vignon-Clementel The 12th International Conference on Complex Networks and their Applications, Nov 2023, Menton, France Communication dans un congrès hal-04275318v1
The impact of reduced left ventricular contractility on retinal perfusion Michael Chang,Alon Harris,Mohamed Zaid,Lorenzo Sala,Marcela Szoposet al. Investigative Ophthalmology & Visual Science, ARVO, Apr 2023, New Orleans, LA, United States Communication dans un congrès hal-04192055v1
The Ocular Mathematical Virtual Simulator: the sensitivity analysis of a validate multiscale model for hemodynamics and biomechanics in the human eye. Lorenzo Sala Workshop Mathematical Modelling of Photoreceptors, Luca Alasio; Benoit Perthame, Jan 2023, Paris, France Communication dans un congrès hal-04248105v1
Sensitivity Analysis of a Mathematical Model Simulating the Post-Hepatectomy Hemodynamics Response Lorenzo Sala,Nicolas Golse,Alexandre Joosten,Eric Vibert,Irene Vignon-Clementel CMBBE 2023 - 18th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering, May 2023, Paris, France. pp.270 - 289 Communication dans un congrès hal-04075698v1
A web-based interface for ocular hemodynamics and biomechanics analysis via the Ocular Mathematical Virtual Simulator Lorenzo Sala,Giovanna Guidoboni,C. Prud’homme,Marcela Szopos,Alice Chandra Verticchio Vercellinet al. ARVO, 2019, Annual Meeting, United States Communication dans un congrès hal-03901634v1
Patient-specific virtual simulator of tissue perfusion in the lamina cribrosa. Lorenzo Sala,Christophe Prud'Homme,Daniele Prada,Fabrizia Salerni,Christophe Trophimeet al. Annual Meeting of Association for Research in Vision and Ophthalmology (ARVO), May 2017, Baltimore, MA, United States Communication dans un congrès hal-01479209v1
The role of HCO3 and NA/K ATPase in the regulation of aqueous humor production: a mathematical model. Riccardo Sacco,Aurelio Giancarlo Mauri,Lorenzo Sala,Simone Cassani,Brent Sieskyet al. Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO), May 2016, Seattle, United States Communication dans un congrès hal-01479193v1

Poster de conférence (2)

A multiscale computational framework for gut microbiota-host interactions Eleonora Pastremoli,Béatrice Laroche,Lorenzo Sala CJC-MA2024 - Congrès des Jeunes Chercheur.e.s en Mathématiques Appliquées, Oct 2024, Lyon, France Poster de conférence hal-04876163v1
Unconditionally stable operator splitting method for a multiscale application in ophthalmology Giovanna Guidoboni,Christophe Prud'Homme,Lorenzo Sala,Marcela Szopos 44e Congrès National d'Analyse Numérique, May 2018, Cap d'Agde, France Poster de conférence hal-01798865v1

Chapitre d'ouvrage (1)

Mathematical Assessment of the Role of Three Factors Entangled in the Development of Glaucoma by Means of the Ocular Mathematical Virtual Simulator Lorenzo Sala,Christophe Prud'Homme,Giovanna Guidoboni,Marcela Szopos,Alon Harris Numerical Mathematics and Advanced Applications ENUMATH 2019, 139 (3), pp.851-860, 2021, Lecture Notes in Computational Science and Engineering, ⟨10.1007/978-3-030-55874-1_84⟩ Chapitre d'ouvrage hal-03474324v1

Pré-publication, Document de travail (3)

A multiscale coupled PDE model of host-microbiota interaction: application to colonic mucosal barrier dynamics Eleonora Pastremoli,Béatrice Laroche,Lorenzo Sala 2026 Pré-publication, Document de travail hal-05524422v1
Eye2Heart : a validated lumped-parameter model bridging cardiovascular and ocular dynamics Lorenzo Sala,Mohamed Zaid,Faith Hughes,Marcela Szopos,Virginia H. Huxleyet al. 2025 Pré-publication, Document de travail hal-05024047v1
Modelling the interplay between the gut microbiota and its host : application to the analysis of diet impact on symbiosis Marie Haghebaert,Béatrice Laroche,Lorenzo Sala,Stanislas Mondot,Joël Doré 2023 Pré-publication, Document de travail hal-04287119v1

Rapport (1)

Hi-POD solution of parametrized fluid dynamics problems: preliminary results Davide Baroli,Cristina Maria Cova,Simona Perotto,Lorenzo Sala,Alessandro Veneziani [Research Report] MOX, Dipartimento di Matematica, Politecnico di Milano. 2016 Rapport (rapport de recherche) hal-01479163v1

Thèse (1)

Mathematical modelling and simulation of ocular blood flows and their interactions Lorenzo Sala Numerical Analysis [math.NA]. Université de Strasbourg, 2019. English. ⟨NNT : 2019STRAD021⟩ Thèse tel-02284233v2

Logiciel (1)

A 3D geometrical model and meshing procedures for the human eyeball Vincent Chabannes,Christophe Prud'Homme,Thomas Saigre,Sala Lorenzo,Marcela Szoposet al. 2025, ⟨swh:1:dir:a275c7afe02abd36a1124d0c6746fc45ee61c4f3⟩ Logiciel hal-05106849v1