Lubomir Vezenkov

Publications

Article dans une revue (21)

Real‐time FRET assay for monitoring detyrosination by TMCP1 and VASH2 Matthieu Simon,Julien Espeut,François Juge,Muriel Amblard,Krzysztof Rogowskiet al. Protein Science, 2025, 34 (12), pp.e70374. ⟨10.1002/pro.70374⟩ Article dans une revue hal-05381834v1
Development of Low-Nanomolar Covalent Epoxide Inhibitors of Tubulin Detyrosinating Enzymes VASH1&2 Anthony Feral,Guillaume Marcellin,Yoann Lannay,Camille Hennebert,Yazid Soufet al. Journal of Medicinal Chemistry, 2025, 68 (17), pp.18335-18355. ⟨10.1021/acs.jmedchem.5c00980⟩ Article dans une revue hal-05328434v1
Peptide-based covalent inhibitor of tubulin detyrosination promotes mesenchymal-to-epithelial transition in lung cancer cells Hathaichanok Impheng,Ghislain Gillard,Nuttanid Numnoi,Anthony Feral,Matthieu Simonet al. Proceedings of the National Academy of Sciences of the United States of America, 2025, 123, 123 (1), pp.e2514990123. ⟨10.1073/pnas.2514990123⟩ Article dans une revue hal-05441335v1
Covalent-reversible peptide-based protease inhibitors. Design, synthesis, and clinical success stories Anthony Feral,Anthony R. Martin,Alexandre Desfoux,Muriel Amblard,Lubomir Vezenkov Amino Acids, In press, ⟨10.1007/s00726-023-03286-1⟩ Article dans une revue (article de synthèse) hal-04167336v1
Kinetic Studies and Temperature‐Induced Morphological Changes of Peptide Decorated Nano‐Objects via Polymerization‐Induced Self‐Assembly Belkacem Tarek Benkhaled,Hamza Chouirfa,Lubomir Vezenkov,Chaimaa Gomri,Arnaud Chaixet al. Macromolecular Chemistry and Physics, In press, ⟨10.1002/macp.202300178⟩ Article dans une revue hal-04223194v1
Morphological evolution of poly(glycerol monomethacrylate)- stat -glycine–phenylalanine–phenylalanine–methacrylamide- b -poly(2-hydroxypropylmethacrylate) (P(GMA- stat -(MAm-GFF))- b -PHPMA) block copolymer nano-objects via polymerization-induced self-assembly T. Dao,Lubomir Vezenkov,Gilles Subra,Muriel Amblard,Vincent Ladmiralet al. Polymer Chemistry, 2023, 14 (3), pp.295-302. ⟨10.1039/d2py01203k⟩ Article dans une revue hal-04222410v1
Newly Synthesized Creatine Derivatives as Potential Neuroprotective and Antioxidant Agents on In Vitro Models of Parkinson’s Disease Ivanka Kostadinova,Magdalena Kondeva-Burdina,Lyubomir Marinov,Lubomir L Vezenkov,Rumyana Simeonova Life, 2023, 13 (1), pp.139. ⟨10.3390/life13010139⟩ Article dans une revue hal-04639051v1
Nano-assemblies with core-forming hydrophobic polypeptide via polymerization-induced self-assembly (PISA) T. P. Tuyen Dao,Lubomir Vezenkov,Gilles Subra,Vincent Ladmiral,M. Semsarilar Polymer Chemistry, 2021, 12 (1), pp.113-121. ⟨10.1039/d0py00793e⟩ Article dans une revue hal-03005857v1
Bottom-up strategies for the synthesis of peptide-based polymers Julie Martin,Alexandre Desfoux,Jean Martinez,Muriel Amblard,Ahmad Mehdiet al. Progress in Polymer Science, 2021, 115, pp.101377. ⟨10.1016/j.progpolymsci.2021.101377⟩ Article dans une revue hal-03161627v1
Self-Assembling Peptide—Polymer Nano-Objects via Polymerization-Induced Self-Assembly Tuyen T. P. Dao,Lubomir Vezenkov,Gilles Subra,Muriel Amblard,Martin Inet al. Macromolecules, 2020, 53 (16), pp.7034-7043. ⟨10.1021/acs.macromol.0c01260⟩ Article dans une revue hal-02915614v1
Direct Synthesis of Peptide‐Containing Silicones: A New Way to Bioactive Materials Julie Martin,Mohammad Wehbi,Cécile Echalier,Sylvie Hunger,Audrey Bethryet al. Chemistry - A European Journal, 2020, 26, pp.12839 - 12845. ⟨10.1002/chem.202001571⟩ Article dans une revue hal-04816986v1
Hydrocarbon-Stapled Peptide Based-Nanoparticles for siRNA Delivery Matthieu Simon,Nabila Laroui,Marianne Heyraud,Guillaume Laconde,Lamiaa Mohamed Ahmed Aliet al. Nanomaterials, 2020, 10 (12), pp.2334. ⟨10.3390/nano10122334⟩ Article dans une revue hal-03053993v1
Evolutionary Divergence of Enzymatic Mechanisms for Tubulin Detyrosination Siem van Der Laan,Maude Lévêque,Guillaume Marcellin,Lubomir Vezenkov,Yoann Lannayet al. Cell Reports, 2019, 29 (12), pp.4159 - 4171. ⟨10.1016/j.celrep.2019.11.074⟩ Article dans une revue hal-03080532v1
Indoloazepinone-Containing Oligomers as Cell-Penetrating (Non)Peptides: Synthesis, Structuration and Internalization Olivier van Der Poorten,Baptiste Legrand,Lubomir Vezenkov,Jean Martinez,Nadir Bettacheet al. Journal of Peptide Science, 2018, 22 (S2), pp.S117. ⟨10.1002/psc.2950⟩ Article dans une revue hal-03576982v1
Indoloazepinone-Constrained Oligomers as Cell-Penetrating and Blood-Brain-Barrier-Permeating Compounds Olivier van Der Poorten,Baptiste Legrand,Lubomir Vezenkov,Júlia García-Pindado,Nadir Bettacheet al. ChemBioChem, 2018, 19 (7), pp.696-705. ⟨10.1002/cbic.201700678⟩ Article dans une revue hal-03564881v1
Ribbon-like Foldamers for Cellular Uptake and Drug Delivery Lubomir L. Vezenkov,Vincent Martin,Nadir Bettache,Matthieu Simon,Alexandre Messerschmittet al. ChemBioChem, 2017, 18 (21), pp.2110-2114. ⟨10.1002/cbic.201700455⟩ Article dans une revue hal-01944639v1
Structure-Activity Relationships of JMV4463, a Vectorized Cathepsin D Inhibitor with Antiproliferative Properties: The Unique Role of the AMPA-Based Vector Lubomir Vezenkov,Clément Sanchez,Virginie Bellet,Vincent Martin,Marie Maynadieret al. ChemMedChem, 2016, 11 (3), pp.302-308. ⟨10.1002/cmdc.201500457⟩ Article dans une revue istex hal-02388735v1
Turning Peptide Sequences into Ribbon Foldamers by a Straightforward Multicyclization Reaction Vincent Martin,Baptiste Legrand,Lubomir Vezenkov,Mathéo Berthet,Gilles Subraet al. Angewandte Chemie International Edition, 2015, 54 (47), pp.13966-13970. ⟨10.1002/anie.201506955⟩ Article dans une revue istex hal-01946536v1
Dipeptide mimic oligomer transporter mediates intracellular delivery of Cathepsin D inhibitors: A potential target for cancer therapy Marie Maynadier,Lubomir Vezenkov,Muriel Amblard,Vincent Martin,Céline Gandreuilet al. Journal of Controlled Release, 2013, 171 (2), pp.251-257. ⟨10.1016/j.jconrel.2013.07.017⟩ Article dans une revue istex hal-03560280v1
Helical Oligomers of Thiazole-Based -Amino Acids: Synthesis and Structural Studies Loic Mathieu,Baptiste Legrand,Cheng Deng,Lubomir Vezenkov,Emmanuel Wengeret al. Angewandte Chemie International Edition, 2013, 52 (23), pp.6006-6010. ⟨10.1002/anie.201302106⟩ Article dans une revue istex hal-01498207v1
A Straightforward Approach for Cellular-Uptake Quantification David Paramelle,Gilles Subra,Lubomir L. Vezenkov,Marie Maynadier,Christophe Andréet al. Angewandte Chemie International Edition, 2010, 49, pp.8240-8243. ⟨10.1002/anie.201003347⟩ Article dans une revue istex hal-00552100v1

Poster de conférence (1)

From peptides to bioactive lactamconstrained foldamers Maxime Fillaudeau,Alexandre Messerschmitt,Arie van Der Lee,Lubomir Vezenkov,Luc Brunelet al. European Peptide Society. 37th European Peptide Symposium (37th EPS) & 14th International Peptide Symposium (14th IPS), Aug 2024, Florence, Italy. Wiley, Journal of Peptide Science, 30 (S2), pp.225-226, 2024 Poster de conférence hal-04811548v1

Brevet (1)

New VASHs inhibitors, conjugates thereof and their uses as drugs or as research tools. Krzysztof Rogowski,Lubomir L. Vezenkov,Muriel Amblard,Siem van Der Laan,Khaled Hachedet al. France, Patent n° : WO2023025861A1. 2023 Brevet hal-04851769v1

Communication dans un congrès (2)

Multi-lactamization reaction for the conception of foldamers and cell penetrating vectors Lubomir Vezenkov,Alexandre Messerschmitt,Baptiste Legrand,Vincent Martin,Nadir Bettacheet al. Proceedings of the 2nd International Multidisciplinary event in Chemistry Between Balard Institut and K.N. Toosi University, Jan 2022, Teheran-Montpellier (Webinaire), France Communication dans un congrès hal-04851702v1
Folded oligomers for Cellular Uptake and Drug Delivery Lubomir L. Vezenkov 9th International Conference of Peptides, Aug 2021, Velingrad, Bulgaria Communication dans un congrès hal-04851744v1