Luigi Agrofoglio

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Publications

LAVR-289, a broad-spectrum antiviral, protects immunosuppressed Syrian hamsters against lethal adenovirus challenge

Ann Tollefson , Anna Cline-Smith , Vincent Roy , Luigi A. Agrofoglio , Getahun Abate et al.

Antiviral Research, 2025, 240, pp.106221. ⟨10.1016/j.antiviral.2025.106221⟩

Article dans une revue hal-05588571v1

LAVR-289, an Acyclo-Nucleoside Phosphonate, Has Broad-Spectrum Activity against Herpesviruses

Sandrine Kappler-Gratias , Charlotte Quentin-Froignant , Elie Marcheteau , José Fernandez , David Boutolleau et al.

ACS Infectious Diseases, 2025, 11 (10), pp.2722-2728. ⟨10.1021/acsinfecdis.5c00171⟩

Article dans une revue hal-05549140v1

LAVR-289, an Orally Bioavailable Inhibitor of Adenovirus Replication In Vitro and In Vivo

Charlotte Quentin-Froignant , Ann Tollefson , Anna Cline-Smith , Sandrine Kappler-Gratias , Nicolas Landrein et al.

ACS Infectious Diseases, 2025, 11 (6), pp.1416-1423. ⟨10.1021/acsinfecdis.5c00170⟩

Article dans une revue hal-05588724v1

Antiviral Activity of the Acyclic Nucleoside Phosphonate Prodrug LAVR-289 against Poxviruses and African Swine Fever Virus

Elie Marcheteau , Estelle Mosca , Gaelle Frenois-Veyrat , Sandrine Kappler-Gratias , Laetitia Boutin et al.

ACS Infectious Diseases, 2025, 11 (6), pp.1623-1634. ⟨10.1021/acsinfecdis.5c00169⟩

Article dans une revue hal-05588572v1

Synthesis of LAVR-289, a new [(Z)-3-(acetoxymethyl)-4-(2,4-diaminopyrimidin-6-yl)oxy-but-2-enyl]phosphonic acid prodrug with pronounced antiviral activity against DNA viruses

Maximes Bessières , Vincent Roy , Tuniyazi Abuduani , Patrick Favetta , Robert Snoeck et al.

European Journal of Medicinal Chemistry, 2024, 271 (7), pp.116412. ⟨10.1016/j.ejmech.2024.116412⟩

Article dans une revue hal-05588577v1

Molecularly Imprinted Polymeric Nanoparticles as Drug Delivery System for Tenofovir, an Acyclic Nucleoside Phosphonate Antiviral

Thomas Mathieu , Patrick Favetta , Luigi Agrofoglio

Pharmaceutics, 2024, 16 (7), pp.965. ⟨10.3390/pharmaceutics16070965⟩

Article dans une revue hal-04790768v1

Synthesis and Antiviral Evaluation of 5-(4-Aryl-1,3-butadiyn-1-yl)-uridines and Their Phosphoramidate Pronucleotides

Evan Saillard , Otmane Bourzikat , Koffi Assa , Vincent Roy , Luigi A. Agrofoglio

Molecules, 2024, 30 (1), pp.96. ⟨10.3390/molecules30010096⟩

Article dans une revue hal-05588574v1

Lyotropic liquid crystal emulsions of LAVR-289: Influence of internal mesophase structure on cytotoxicity and in-vitro antiviral activity

Mathias Brouillard , Thomas Mathieu , Samuel Guillot , Fabienne Méducin , Vincent Roy et al.

International Journal of Pharmaceutics, 2024, 665, pp.124683. ⟨10.1016/j.ijpharm.2024.124683⟩

Article dans une revue hal-05588575v1

Cobalt-assisted route to rare carbocyclic C -ribonucleosides

Andrea C. Ojeda-Porras , Vincent Roy , Otmane Bourzikat , Patrick Favetta , L. Agrofoglio

RSC Advances, 2023, 13 (44), pp.30777-30786. ⟨10.1039/D3RA04937J⟩

Article dans une revue hal-04790673v1

Antibiotics and Antibiotic Resistance—Mur Ligases as an Antibacterial Target

Vincent Hervin , Vincent Roy , Luigi A. Agrofoglio

Molecules, 2023, 28 (24), pp.8076. ⟨10.3390/molecules28248076⟩

Article dans une revue hal-05588578v1
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Nucleosides and emerging viruses: A new story

Vincent Roy , Luigi Agrofoglio

Drug Discovery Today, 2022, 27 (7), pp.1945-1953. ⟨10.1016/j.drudis.2022.02.013⟩

Article dans une revue hal-03859490v1

Synthesis of Novel 3’,3’‐cyclic Dinucleotide Analogues Targeting STING Protein

Jérémy Magand , Vincent Roy , Hervé Meudal , Stéphanie Rose , Valérie Quesniaux et al.

Asian Journal of Organic Chemistry, 2022, 12 (1), ⟨10.1002/ajoc.202200597⟩

Article dans une revue hal-05588712v1
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Synthesis of novel 3’,3’‐cyclic dinucleotide analogues targeting STING protein

Jérémy Magand , Vincent Roy , Hervé Meudal , Stéphanie Rose , Valérie Quesniaux et al.

Asian Journal of Organic Chemistry, 2022, 2022, pp.e202200597. ⟨10.1002/ajoc.202200597⟩

Article dans une revue hal-03859427v1
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Synthesis and structure–activity relationship studies of pyrido [1,2-e]purine-2,4(1H,3H)-dione derivatives targeting Flavin-Dependent $Thymidylate\ Synthase$ in $Mycobacterium\ tuberculosis$

Nicolas G. Biteau , Vincent Roy , Cyril Nicolas , Hubert F Becker , Jean-Christophe Lambry et al.

Molecules, 2022, 27, pp.6216. ⟨10.3390/molecules27196216⟩

Article dans une revue hal-03798565v1
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A Tunable Approach to C-Linked Analogs of Glycosamines

Tuniyazi Abuduaini , Sizhe Li , Vincent Roy , Luigi A Agrofoglio , Olivier R Martin et al.

Journal of Organic Chemistry, In press, ⟨10.1021/acs.joc.2c01650⟩

Article dans une revue hal-03798583v1

Chemical Approaches to Carbocyclic Nucleosides

Andrea C. Ojeda-Porras , Vincent Roy , Luigi A. Agrofoglio

The Chemical Record, 2022, 22 (5), ⟨10.1002/tcr.202100307⟩

Article dans une revue hal-03890854v1

Molecularly Imprinted Hydrogels Selective to Ribavirin as New Drug Delivery Systems to Improve Efficiency of Antiviral Nucleoside Analogue: A Proof‐of‐Concept Study with Influenza A Virus

Mohamed Ayari , Patrick Favetta , Dawid Warszycki , Virginie Vasseur , Virginie Herve et al.

Macromolecular Bioscience, 2021, 13 (7), pp.2100291. ⟨10.1002/mabi.202100291⟩

Article dans une revue hal-03557328v1
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Design, synthesis and biological evaluation of 2-substituted-6-[(4-substituted-1-piperidyl)methyl]-1H-benzimidazoles as inhibitors of ebola virus infection

Maxime Bessières , Elżbieta Plebanek , Payel Chatterjee , Punya Shrivastava-Ranjan , Mike Flint et al.

European Journal of Medicinal Chemistry, 2021, 214, pp.113211. ⟨10.1016/j.ejmech.2021.113211⟩

Article dans une revue hal-03717303v1
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Synthesis and Antiviral Evaluation of (1,4-Disubstituted-1,2,3-Triazol)-(E)-2-Methyl-but-2-Enyl Nucleoside Phosphonate Prodrugs

Tuniyazi Abuduaini , Vincent Roy , Julien Marlet , Catherine Gaudy-Graffin , Denys Brand et al.

Molecules, 2021, 26 (5), pp.1493. ⟨10.3390/molecules26051493⟩

Article dans une revue inserm-03412066v1

Vers un nouvel antiviral puissant contre les virus à ADN

Vincent Roy , Patrick Favetta , Luigi A. Agrofoglio

Microscoop. Hors-série, 2021, HS21, pp.8-9

Article dans une revue hal-03658279v1

Circadian and chemotherapy-related changes in urinary modified nucleosides excretion in patients with metastatic colorectal cancer

S. Dulong , Q. Huang , P. Innominato , A. Karaboue , M. Bouchahda et al.

Scientific Reports, 2021, 11 (1), pp.24015. ⟨10.1038/s41598-021-03247-2⟩

Article dans une revue hal-05588725v1
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Synthesis of acyclic nucleoside phosphonates targeting Flavin-Dependent Thymidylate Synthase in Mycobacterium tuberculosis

Nicolas G Biteau , Vincent Roy , J.-C. Lambry , Hubert F Becker , Hannu Myllykallio et al.

Bioorganic and Medicinal Chemistry Letters, 2021, 46, pp.116351. ⟨10.1016/j.bmc.2021.116351⟩

Article dans une revue hal-03322503v1
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Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–6

Jean Jacques Vanden Eynde , Arduino Aleksander Mangoni , Jarkko Rautio , Jérôme Leprince , Yasu-Taka Azuma et al.

Molecules, 2020, 25 (1), pp.119. ⟨10.3390/molecules25010119⟩

Article dans une revue hal-03321491v1

Thiopurine Derivative-Induced Fpg/Nei DNA Glycosylase Inhibition: Structural, Dynamic and Functional Insights

Charlotte Rieux , Stéphane Goffinont , Franck Coste , Zahira Tber , Julien Cros et al.

International Journal of Molecular Sciences, 2020, 21 (6), pp.2058. ⟨10.3390/ijms21062058⟩

Article dans une revue hal-05588581v1
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Thiopurine Derivative-Induced Fpg/Nei DNA Glycosylase Inhibition: Structural, Dynamic and Functional Insights

Charlotte Rieux , Stéphane Goffinont , Franck Coste , Zahira Tber , Julien Cros et al.

International Journal of Molecular Sciences, 2020, 21 (6), pp.2058. ⟨10.3390/ijms21062058⟩

Article dans une revue hal-03082414v1

Design and Synthesis of Various 5′-Deoxy-5′-(4-Substituted-1,2,3-Triazol-1-yl)-Uridine Analogues as Inhibitors of Mycobacterium tuberculosis Mur Ligases

Vincent Hervin , Ritu Arora , Jyoti Rani , Srinivasan Ramchandran , Urmi Bajpai et al.

Molecules, 2020, 25 (21), pp.4953. ⟨10.3390/molecules25214953⟩

Article dans une revue hal-05588580v1
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Monitoring of phosphorylation using immobilized kinases by on-line enzyme bioreactors hyphenated with High-Resolution Mass Spectrometry

Justine Ferey , David da Silva , Cyril Colas , Pierre Lafite , Dimitrios Topalis et al.

Talanta, 2019, 205, pp.120120. ⟨10.1016/j.talanta.2019.120120⟩

Article dans une revue hal-03466045v1
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Synthesis of imprinted hydrogel microbeads by inverse Pickering emulsion to controlled release of adenosine 5′‑monophosphate

Mohamed Ayari , Porkodi Kadhirvel , Patrick Favetta , Bernard Plano , Corinne Dejous et al.

Materials Science and Engineering: C, 2019, 101, pp.254-263. ⟨10.1016/j.msec.2019.03.102⟩

Article dans une revue hal-02299722v1
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Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–4

Arduino A Mangoni , Catherine Guillou , Jean Jacques Vanden Eynde , Christopher Hulme , Josef Jampilek et al.

Molecules, 2019, 24 (1), pp.130. ⟨10.3390/molecules24010130⟩

Article dans une revue hal-02346060v1
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Microwave-assisted Suzuki-Miyaura and Sonogashira coupling of 4-Chloro-2-(trifluoromethyl)pyrido[1,2-e]purine derivatives

Zahira Tber , Nicolas G. Biteau , Luigi Agrofoglio , Julien Cros , Stéphane Goffinont et al.

European Journal of Organic Chemistry, 2019, 2019, pp.5756-5767. ⟨10.1002/ejoc.201900921⟩

Article dans une revue hal-02347523v1
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Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–5

Arduino Mangoni , Jean Eynde , Josef Jampilek , Dimitra Hadjipavlou-Litina , Hong Liu et al.

Molecules, 2019, 24 (13), pp.2415. ⟨10.3390/molecules24132415⟩

Article dans une revue hal-03170800v1

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–6

Jean Jacques Vanden Eynde , Arduino Mangoni , Jarkko Rautio , Jérôme Leprince , Yasu-Taka Azuma et al.

Molecules, 2019, 25 (1), pp.119. ⟨10.3390/molecules25010119⟩

Article dans une revue hal-05588582v1
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Monitoring of successive phosphorylations of thymidine using free and immobilized human nucleoside/nucleotide kinases by Flow Injection Analysis with High-Resolution Mass Spectrometry

Justine Ferey , David da Silva , Cyril Colas , Reine Nehmé , Pierre Lafite et al.

Analytica Chimica Acta, 2019, 1049, pp.115-122. ⟨10.1016/j.aca.2018.10.032⟩

Article dans une revue hal-02090335v1

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–4

Arduino Mangoni , Catherine Guillou , Jean Vanden Eynde , Christopher Hulme , Josef Jampilek et al.

Molecules, 2018, 24 (1), pp.130. ⟨10.3390/molecules24010130⟩

Article dans une revue hal-05588611v1

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-3

Arduino Mangoni , Tiziano Tuccinardi , Simona Collina , Jean Vanden Eynde , Diego Muñoz-Torrero et al.

Molecules, 2018, 23 (7), pp.1596. ⟨10.3390/molecules23071596⟩

Article dans une revue hal-05588612v1

Highly convergent synthesis and antiviral activity of (E)-but-2-enyl nucleoside phosphonoamidates

Maxime Bessières , Vincent Hervin , Vincent Roy , Agnes Chartier , Robert Snoeck et al.

European Journal of Medicinal Chemistry, 2018, 146, pp.678-686. ⟨10.1016/j.ejmech.2018.01.086⟩

Article dans une revue hal-03090373v1

Synthesis and characterization of various 5′-dye-labeled ribonucleosides

Coralie de Schutter , Vincent Roy , Patrick Favetta , Corentin Pavageau , Stéphane Maisonneuve et al.

Organic & Biomolecular Chemistry, 2018, 16 (35), pp.6552-6563. ⟨10.1039/C8OB01606B⟩

Article dans une revue hal-03863168v1

Synthesis and characterization of various 5′-dye-labeled ribonucleosides

Coralie de Schutter , Vincent Roy , Patrick Favetta , Corentin Pavageau , Stéphane Maisonneuve et al.

Organic & Biomolecular Chemistry, 2018, 16 (35), pp.6552-6563. ⟨10.1039/c8ob01606b⟩

Article dans une revue hal-05588609v1
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Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-3

Arduino A Mangoni , Tiziano Tuccinardi , Simona Collina , Jean Jacques Vanden Eynde , Diego Muñoz-Torrero et al.

Molecules, 2018, 23 (7), pp.1596. ⟨10.3390/molecules23071596⟩

Article dans une revue hal-02346050v1

Highly convergent synthesis and antiviral activity of (E)-but-2-enyl nucleoside phosphonoamidates

Maxime Bessières , Vincent Hervin , Vincent Roy , Agnès Chartier , Robert Snoeck et al.

European Journal of Medicinal Chemistry, 2018, 146, pp.678-686. ⟨10.1016/j.ejmech.2018.01.086⟩

Article dans une revue hal-05588607v1

Selective inhibition of human cathepsin S by 2,4,6-trisubstituted 1,3,5-triazine analogs

Zahira Tber , Mylène Wartenberg , Jean-Eddy Jacques , Vincent Roy , Fabien Lecaille et al.

Bioorganic and Medicinal Chemistry, 2018, 26 (14), pp.4310-4319. ⟨10.1016/j.bmc.2018.07.032⟩

Article dans une revue hal-04678746v1

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–2

Diego Muñoz-Torrero , Arduino Mangoni , Hong Liu , Christopher Hulme , Jarkko Rautio et al.

Molecules, 2017, 23 (1), pp.65. ⟨10.3390/molecules23010065⟩

Article dans une revue hal-05588606v1
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Synthesis of 5,5-difluoro-5-phosphono-pent-2-en-1-yl nucleosides as potential antiviral agents

Florian Chevrier , Zein Chamas , Thierry Lequeux , Emmanuel Pfund , G. Andrei et al.

RSC Advances, 2017, 7 (51), pp.32282 - 32287. ⟨10.1039/c7ra05153k⟩

Article dans une revue hal-01829613v1

Tailor‐Made Molecularly Imprinted Polymer for Selective Recognition of the Urinary Tumor Marker Pseudouridine

Aleksandra Krstulja , Stefania Lettieri , Andrew Hall , Vincent Roy , Patrick Favetta et al.

Macromolecular Bioscience, 2017, 17 (12), ⟨10.1002/mabi.201700250⟩

Article dans une revue hal-05588614v1
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Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-2 Molecules

Diego Muñoz-Torrero , Arduino A Mangoni , Hong Liu , Christopher Hulme , Jarkko Rautio et al.

Molecules, 2017, 2018, 23 (1), pp.65-74. ⟨10.3390/molecules23010065⟩

Article dans une revue hal-02345682v1

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–2

Diego Muñoz-Torrero , Arduino Mangoni , Hong Liu , Christopher Hulme , Jarkko Rautio et al.

Molecules, 2017, 23 (1), pp.65. ⟨10.3390/molecules23010065⟩

Article dans une revue hal-05588586v1

Synthesis of 5,5-difluoro-5-phosphono-pent-2-en-1-yl nucleosides as potential antiviral agents

F. Chevrier , Z. Chamas , T. Lequeux , E. Pfund , G. Andrei et al.

RSC Advances, 2017, 7 (51), pp.32282-32287. ⟨10.1039/c7ra05153k⟩

Article dans une revue hal-05588613v1

Love Acoustic Wave-Based Devices and Molecularly-Imprinted Polymers as Versatile Sensors for Electronic Nose or Tongue for Cancer Monitoring

Corinne Dejous , Hamida Hallil , Vincent Raimbault , Jean-Luc Lachaud , Bernard Plano et al.

Sensors, 2016, 16 (6), pp.915. ⟨10.3390/s16060915⟩

Article dans une revue hal-05588615v1

Sonication‐Assisted Synthesis of (E) ‐2‐Methyl‐but‐2‐enyl Nucleoside Phosphonate Prodrugs

Maxime Bessières , Ozkan Sari , Vincent Roy , Dawid Warszycki , Andrzej Bojarski et al.

ChemistrySelect, 2016, 1 (12), pp.3108-3113. ⟨10.1002/slct.201600879⟩

Article dans une revue hal-05588616v1
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Love Acoustic Wave-Based Devices and Molecularly-Imprinted Polymers as Versatile Sensors for Electronic Nose or Tongue for Cancer Monitoring

Corinne Dejous , Hamida Hallil , Vincent Raimbault , Jean-Luc Lachaud , Bernard Plano et al.

Sensors, 2016, 16 (6), pp.915. ⟨10.3390/s16060915⟩

Article dans une revue hal-01356195v1

Straightforward synthesis of 2,4,6-trisubstituted 1,3,5-triazine compounds targeting cysteine cathepsins K and S

Elżbieta Plebanek , Florian Chevrier , Vincent Roy , Thibault Garenne , Fabien Lecaille et al.

European Journal of Medicinal Chemistry, 2016, 121, pp.12-20. ⟨10.1016/j.ejmech.2016.05.009⟩

Article dans une revue hal-05588617v1

Synthesis of dihydropyrimidine α,γ-diketobutanoic acid derivatives targeting HIV integrase

Ozkan Sari , Vincent Roy , Mathieu Métifiot , Christophe Marchand , Yves Pommier et al.

European Journal of Medicinal Chemistry, 2015, 104, pp.127-138. ⟨10.1016/j.ejmech.2015.09.015⟩

Article dans une revue hal-02904762v1

Synthesis of a molecularly imprinted polymer to isolate glucosamine from plant extracts by an ionic–non‐covalent dual approach

N. Henry , P. Favetta , R. Delépée , J.‐m. Seigneuret , Luigi A. Agrofoglio

International Journal of Cosmetic Science, 2015, 37 (2), pp.196-206. ⟨10.1111/ics.12182⟩

Article dans une revue istex hal-05588620v1

Synthesis of a molecularly imprinted polymer to isolate glucosamine from plant extracts by an ionic-non-covalent dual approach

N. Henry , P. Favetta , R. Delépée , J.-M. Seigneuret , L. Agrofoglio

International Journal of Cosmetic Science, 2015, 37 (2), pp.196-206. ⟨10.1111/ics.12182⟩

Article dans une revue istex hal-03593458v1

Recent Progress for the Synthesis of Selected Carbocyclic Nucleosides

Maxime Bessières , Florian Chevrier , Vincent Roy , Luigi A. Agrofoglio

Future Medicinal Chemistry, 2015, 7 (13), pp.1809-1828. ⟨10.4155/fmc.15.105⟩

Article dans une revue hal-05588619v1

Active site labeling of cysteine cathepsins by a straightforward diazomethylketone probe derived from the N-terminus of human cystatin C

Thibaut Garenne , Ahlame Saidi , Brendan Gilmore , Elżbieta Niemiec , Vincent Roy et al.

Biochemical and Biophysical Research Communications, 2015, 460 (2), pp.250-254. ⟨10.1016/j.bbrc.2015.03.020⟩

Article dans une revue istex hal-05588618v1

Synthesis of Fluorine-Containing 3,3-Disubstituted Oxetanes and Alkylidene Oxetanes

Romain Laporte , Anais Prunier , Emmanuel Pfund , Vincent Roy , Luigi Agrofoglio et al.

European Journal of Organic Chemistry, 2015, 2015 (14), pp.3121-3128. ⟨10.1002/ejoc.201500172⟩

Article dans une revue istex hal-02348052v1

Love Wave Sensor Based on Thin Film Molecularly Imprinted Polymer: Study of VOCs Adsorption

Hamida Hallil , Nima Omar-Aouled , Bernard Plano , Raphaël Delépée , Luigi A. Agrofoglio et al.

Journal of Integrated Circuits and Systems, 2014, 9 (2), pp.118-122

Article dans une revue hal-01241891v1

Detection of urinary modified nucleosides by a bulk acoustic wave MIP sensor - Results and future work

Luigi A. Agrofoglio , Aleksandra Krstulja , Coralie de Schutter , Patrick Favetta , Raphaël Delépée et al.

Innovation and Research in BioMedical engineering, 2014, 35 (2), pp.66-71. ⟨10.1016/j.irbm.2014.02.009⟩

Article dans une revue istex hal-00988691v1

Evaluation of molecularly imprinted polymers using 2′,3′,5′-tri-O-acyluridines as templates for pyrimidine nucleoside recognition

Aleksandra Krstulja , Stefania Lettieri , Andrew Hall , Raphael Delépée , Patrick Favetta et al.

Analytical and Bioanalytical Chemistry, 2014, 406 (25), pp.6275-6284. ⟨10.1007/s00216-014-8017-z⟩

Article dans une revue hal-03593455v1

A convenient, highly selective and eco-friendly N-Boc protection of pyrimidines under microwave irradiation

Maxime Bessières , Vincent Roy , Luigi A. Agrofoglio

RSC Advances, 2014, 4 (104), pp.59747-59749. ⟨10.1039/C4RA13033B⟩

Article dans une revue hal-05588726v1

Study of gaseous compounds adsorption with a Love wave sensor based on molecularly imprinted polymer thin film

Nima Omar-Aouled , Naïma Lebal , Hamida Hallil , Raphael Delepee , Luigi A. Agrofoglio et al.

Sensors & Transducers., 2013, 149 (2), pp.37-42

Article dans une revue hal-00817577v1

Synthesis and broad spectrum antiviral evaluation of bis(POM) prodrugs of novel acyclic nucleosides

Manabu Hamada , Vincent Roy , Tamara Mcbrayer , Tony Whitaker , Cesar Urbina-Blanco et al.

European Journal of Medicinal Chemistry, 2013, 67, pp.398-408. ⟨10.1016/j.ejmech.2013.06.053⟩

Article dans une revue hal-05588728v1

Combination of computational methods, adsorption isotherms and selectivity tests for the conception of a mixed non-covalent–semi-covalent molecularly imprinted polymer of vanillin

Kinga Puzio , Raphaël Delépée , Richard Vidal , Luigi Agrofoglio

Analytica Chimica Acta, 2013, 790, pp.47-55. ⟨10.1016/j.aca.2013.06.036⟩

Article dans une revue istex hal-03593453v1

Phase I Dose‐Escalation Pharmacokinetics of AZT‐P‐ddI (IVX‐E‐59) in Patients with Human Immunodeficiency Virus

Xiao‐jian Zhou , Kathleen Squires , Xin‐ru Pan-Zhou , Steve Bernhard , Luigi A. Agrofoglio et al.

Journal of Clinical Pharmacology, 2013, 37 (3), pp.201-213. ⟨10.1002/j.1552-4604.1997.tb04782.x⟩

Article dans une revue istex hal-05588851v1

Nucleosides analogs recognition by Molecularly Imprinted Polymer- coated Love wave sensor

Naïma Lebal , Hamida Hallil , Corinne Dejous , B. Plano , Aleksandra Krstulja et al.

Micro and Nano Letters, 2013, 8 (10), pp.563-566. ⟨10.1049/mnl.2013.0207⟩

Article dans une revue hal-00847369v1

The Preparation of Trisubstituted Alkenyl Nucleoside Phosphonates under Ultrasound-Assisted Olefin Cross-Metathesis

Ozkan Sari , Manabu Hamada , Vincent Roy , Steven Nolan , Luigi A. Agrofoglio

Organic Letters, 2013, 15 (17), pp.4390-4393. ⟨10.1021/ol401922r⟩

Article dans une revue hal-05588727v1

Synthesis of water-compatible imprinted polymers of in situ produced fructosazine and 2,5-deoxyfructosazine

Nathaly Henry , Raphaël Delépée , Jean-Marc Seigneuret , Luigi Agrofoglio

Talanta, 2012, 99, pp.816-823. ⟨10.1016/j.talanta.2012.07.035⟩

Article dans une revue istex hal-03593450v1

Synthesis and antiviral evaluation of bis(POM) prodrugs of (E)-[4′-phosphono-but-2′-en-1′-yl]purine nucleosides

Ugo Pradère , Vincent Roy , Aurélien Montagu , Ozkan Sari , Manabu Hamada et al.

European Journal of Medicinal Chemistry, 2012, 57, pp.126-133. ⟨10.1016/j.ejmech.2012.08.042⟩

Article dans une revue istex hal-05588730v1

Efficient Synthesis of Unprotected C-5-Aryl/Heteroaryl-2'-deoxyuridine via a Suzuki-Miyaura Reaction in Aqueous Media

Nathalie Fresneau , Marie-Aude Hiebel , Luigi A. Agrofoglio , Sabine Berteina-Raboin

Molecules, 2012, 17 (12), pp.14409-14417. ⟨10.3390/molecules171214409⟩

Article dans une revue hal-05588729v1

Synthesis and antiviral evaluation of C5-substituted-(1,3-diyne)-2′-deoxyuridines

Ozkan Sari , Vincent Roy , Jan Balzarini , Robert Snoeck , Graciela Andrei et al.

European Journal of Medicinal Chemistry, 2012, 53, pp.220-228. ⟨10.1016/j.ejmech.2012.04.001⟩

Article dans une revue istex hal-05588731v1

One-pot Sonogashira-cyclization protocol to obtain substituted furopyrimidine nucleosides in aqueous conditions

Nathalie Fresneau , Marie-Aude Hiebel , Luigi A. Agrofoglio , Sabine Berteina-Raboin

Tetrahedron Letters, 2012, 53 (14), pp.1760-1763. ⟨10.1016/j.tetlet.2012.01.106⟩

Article dans une revue istex hal-05588732v1

Synthesis and Anti-HIV Evaluation of 3′-Triazolo Nucleosides

Vincent Roy , Aleksandr Obikhod , Hong-Wang Zhang , Steven Coats , Brian Herman et al.

Nucleosides, Nucleotides and Nucleic Acids, 2011, 30 (4), pp.264-270. ⟨10.1080/15257770.2011.580291⟩

Article dans une revue hal-05588733v1

Expeditious convergent procedure for the preparation of bis(POC) prodrugs of new (E)-4-phosphono-but-2-en-1-yl nucleosides

Aurélien Montagu , Ugo Pradére , Vincent Roy , Steven Nolan , Luigi A. Agrofoglio

Tetrahedron, 2011, 67 (29), pp.5319-5328. ⟨10.1016/j.tet.2011.05.017⟩

Article dans une revue istex hal-05588746v1

In Situ One-Step Method for Synthesis of “Click”-Functionalized Monolithic Stationary Phase for Capillary Electrochromatography

Aleksander Salwiński , Vincent Roy , Luigi Agrofoglio , Raphaël Delépée

Macromolecular Chemistry and Physics, 2011, 212 (24), pp.2700-2707. ⟨10.1002/macp.201100526⟩

Article dans une revue istex hal-03593449v1

Synthesis of new C5-(1-substituted-1,2,3-triazol-4 or 5-yl)-2′-deoxyuridines and their antiviral evaluation

Aurélien Montagu , Vincent Roy , Jan Balzarini , Robert Snoeck , Graciela Andrei et al.

European Journal of Medicinal Chemistry, 2011, 46 (2), pp.778-786. ⟨10.1016/j.ejmech.2010.12.017⟩

Article dans une revue istex hal-05588749v1

The Shortest Strategy for Generating Phosphonate Prodrugs by Olefin Cross‐Metathesis – Application to Acyclonucleoside Phosphonates

Ugo Pradère , Hervé Clavier , Vincent Roy , Steven Nolan , Luigi A. Agrofoglio

European Journal of Organic Chemistry, 2011, 2011 (36), pp.7324-7330. ⟨10.1002/ejoc.201101111⟩

Article dans une revue istex hal-05588734v1

3′-(1,2,3-Triazol-1-yl)-3′-deoxythymidine analogs as substrates for human and Ureaplasma parvum thymidine kinase for structure–activity investigations

Jay Lin , Vincent Roy , Liya Wang , Li You , Luigi A. Agrofoglio et al.

Bioorganic and Medicinal Chemistry, 2010, 18 (9), pp.3261-3269. ⟨10.1016/j.bmc.2010.03.023⟩

Article dans une revue hal-05588752v1

Potential and Perspectives of Cyclonucleosides

A. Mieczkowski , Luigi A. Agrofoglio

Current Medicinal Chemistry, 2010, 17 (15), pp.1527-1549. ⟨10.2174/092986710790979962⟩

Article dans une revue istex hal-05588756v1

Novel Antiviral C5-Substituted Pyrimidine Acyclic Nucleoside Phosphonates Selected as Human Thymidylate Kinase Substrates

Dimitri Topalis , Ugo Pradère , Vincent Roy , Christophe Caillat , Ahmed Azzouzi et al.

Journal of Medicinal Chemistry, 2010, 54 (1), pp.222-232. ⟨10.1021/jm1011462⟩

Article dans une revue hal-05588748v1

Preparation of Carbocyclic C ‐Nucleosides from α‐Chlorooxime Precursor

Ugo Pradere , Hiroki Kumamoto , Vincent Roy , Luigi A. Agrofoglio

European Journal of Organic Chemistry, 2010, 2010 (4), pp.749-754. ⟨10.1002/ejoc.200900950⟩

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Human and viral nucleoside/nucleotide kinases involved in antiviral drug activation: Structural and catalytic properties

Dominique Deville-Bonne , Chahrazade El Amri , Philippe Meyer , Yuxing Chen , Luigi A. Agrofoglio et al.

Antiviral Research, 2010, 86 (1), pp.101-120. ⟨10.1016/j.antiviral.2010.02.001⟩

Article dans une revue istex hal-05588750v1

Microwave-Assisted Syntheses of Nucleosides and Their Precursors

Vincent Roy , Ugo Pradère , Luigi A. Agrofoglio

Future Medicinal Chemistry, 2010, 2 (2), pp.177-192. ⟨10.4155/fmc.09.156⟩

Article dans une revue hal-05588754v1

Preparation of Cyclonucleosides

Adam Mieczkowski , Vincent Roy , Luigi A. Agrofoglio

Chemical Reviews, 2009, 110 (4), pp.1828-1856. ⟨10.1021/cr900329y⟩

Article dans une revue hal-05588753v1

Click Azide‐Alkyne Cycloaddition for the Synthesis of D ‐(–)‐1,4‐Disubstituted Triazolo‐Carbanucleosides

Julie Broggi , Hiroki Kumamoto , Sabine Berteina-Raboin , Steven Nolan , Luigi A. Agrofoglio

European Journal of Organic Chemistry, 2009, 2009 (12), pp.1880-1888. ⟨10.1002/ejoc.200801124⟩

Article dans une revue istex hal-05588766v1
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Phosphorylation of dGMP analogs by vaccinia virus TMP kinase and human GMP kinase.

Constance Auvynet , Dimitri Topalis , Christophe Caillat , Hélène Munier-Lehmann , Edward Seclaman et al.

Biochemical and Biophysical Research Communications, 2009, 388 (1), pp.6-11. ⟨10.1016/j.bbrc.2009.07.089⟩

Article dans une revue pasteur-00417244v1

Synthesis of (±)-1,2,3-triazolo-3′-deoxy-4′-hydroxymethyl carbanucleosides via ‘click’ cycloaddition

Julie Broggi , Nicolas Joubert , Silvia Díez-González , Sabine Berteina-Raboin , Thomas Zevaco et al.

Tetrahedron, 2009, 65 (6), pp.1162-1170. ⟨10.1016/j.tet.2008.11.065⟩

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Preparation of C-5-substituted 6,5′-O-anhydrouridine by Sn–Pd transmetallation-coupling process and their use

Adam Mieczkowski , Jerome Blu , Vincent Roy , Luigi A. Agrofoglio

Tetrahedron, 2009, 65 (47), pp.9791-9796. ⟨10.1016/j.tet.2009.09.075⟩

Article dans une revue istex hal-05588759v1

Molecular imprinting of AMP by an ionic-noncovalent dual approach

Florent Breton , Raphaël Delépée , Luigi Agrofoglio

Journal of Separation Science, 2009, 32 (19), pp.3285-3291. ⟨10.1002/jssc.200900226⟩

Article dans une revue istex hal-03593445v1

A short and stereoselective synthesis of carbocyclic alpha ‐l‐dideoxyhomonucleosides

F. Girard , M.‐g. Lee , Luigi A. Agrofoglio , A. Fridland

Journal of Heterocyclic Chemistry, 2009, 35 (4), pp.911-913. ⟨10.1002/jhet.5570350421⟩

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Preparation of C5-substituted O6,5′-cyclouridine

Adam Mieczkowski , Pauline Peltier , Thomas Zevaco , Luigi A. Agrofoglio

Tetrahedron, 2009, 65 (20), pp.4053-4059. ⟨10.1016/j.tet.2009.02.077⟩

Article dans une revue istex hal-05588761v1

Preparation of ribavirin analogues by copper- and ruthenium-catalyzed azide-alkyne 1,3-dipolar cycloaddition

Ugo Pradere , Vincent Roy , Tamara Mcbrayer , Raymond Schinazi , Luigi A. Agrofoglio

Tetrahedron, 2008, 64 (38), pp.9044-9051. ⟨10.1016/j.tet.2008.07.007⟩

Article dans une revue hal-05588767v1

Evaluation of C-5 Substituted Uracil Acyclic Phosphonates as Substrates or Inhibitors for DTMP and UMP–CMP Kinases and Potential Antipox Derivatives

Dimitri Topalis , Julie Broggi , Julie A.C. Alexandre , Ugo Pradère , Vincent Roy et al.

Antiviral Research, 2008, 78 (2), pp.A65. ⟨10.1016/j.antiviral.2008.01.142⟩

Article dans une revue istex hal-05588776v1

Preparation of acyclo nucleoside phosphonate analogues based on cross-metathesis

Hiroki Kumamoto , Dimitri Topalis , Julie Broggi , Ugo Pradère , Vincent Roy et al.

Tetrahedron, 2008, 64 (16), pp.3517-3526. ⟨10.1016/j.tet.2008.01.140⟩

Article dans une revue istex hal-05588774v1

Molecularly imprinted polymer of 5-methyluridine for solid-phase extraction of pyrimidine nucleoside cancer markers in urine

Damien Jégourel , Raphaël Delépée , Florent Breton , Antoine Rolland , Richard Vidal et al.

Bioorganic and Medicinal Chemistry Letters, 2008, 16 (19), pp.8932-8939. ⟨10.1016/j.bmc.2008.08.063⟩

Article dans une revue istex hal-03593440v1
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Crystal structure of poxvirus thymidylate kinase: an unexpected dimerization has implications for antiviral therapy.

Christophe Caillat , Dimitri Topalis , Luigi A. Agrofoglio , Sylvie Pochet , Jan Balzarini et al.

Proceedings of the National Academy of Sciences of the United States of America, 2008, 105 (44), pp.16900-5. ⟨10.1073/pnas.0804525105⟩

Article dans une revue pasteur-00347333v1

Study of Copper(I) Catalysts for the Synthesis of Carbanucleosides via Azide-Alkyne 1,3-Dipolar Cycloaddition

Julie Broggi , Silvia Díez-González , Jeffrey Petersen , Sabine Berteina-Raboin , Steven Nolan et al.

Synthesis: Journal of Synthetic Organic Chemistry, 2008, 2008 (1), pp.141-148. ⟨10.1055/s-2007-990943⟩

Article dans une revue hal-05588781v1

Synthesis and anti-HIV activity of 5-haloethynyl and 5-(1,2-dihalo)vinyl analogues of AZT and FLT

Nicolas Joubert , Franck Amblard , Kimberly Rapp , Raymond Schinazi , Luigi A. Agrofoglio

Tetrahedron, 2008, 64 (19), pp.4444-4452. ⟨10.1016/j.tet.2008.02.079⟩

Article dans une revue hal-05588773v1

Microwave-Assisted Silylation-Amination of Uracil Acyclonucleosides to 4-Alkylamino-2(1 H )-Pyrimidinone Analogues

Vincent Roy , Adam Mieczkowski , Dimitri Topalis , Sabine Berteina-Raboin , Dominique Deville-Bonne et al.

Synthesis: Journal of Synthetic Organic Chemistry, 2008, 2008 (13), pp.2127-2133. ⟨10.1055/s-2008-1067094⟩

Article dans une revue hal-05588770v1

Selective adenosine-5′-monophosphate uptake by water-compatible molecularly imprinted polymer

Florent Breton , Raphaël Delépée , Damien Jégourel , Dominique Deville-Bonne , Luigi Agrofoglio

Analytica Chimica Acta, 2008, 616 (2), pp.222-229. ⟨10.1016/j.aca.2008.04.025⟩

Article dans une revue istex hal-03593439v1

Mass Spectrometry Based Methods for Analysis of Nucleosides as Antiviral Drugs and Potential Tumor Biomarkers

Luigi Agrofoglio , Vincent Bezy , Patrick Chaimbault , Raphaël Delépée , Boutaina Rhourri et al.

Nucleosides, Nucleotides and Nucleic Acids, 2007, 26 (10-12), pp.1523-1527. ⟨10.1080/15257770701544336⟩

Article dans une revue hal-03593436v1

Specificity enhancement with LC‐positive ESI‐MS/MS for the measurement of nucleotides: application to the quantitative determination of carbovir triphosphate, lamivudine triphosphate and tenofovir diphosphate in human peripheral blood mononuclear cells

Alain Pruvost , Frédéric Théodoro , Luigi A. Agrofoglio , Eugenia Negredo , Henri Bénech

Journal of Mass Spectrometry, 2007, 43 (2), pp.224-233. ⟨10.1002/jms.1294⟩

Article dans une revue istex hal-05588778v1

EFFICIENT SYNTHESIS OF D -[1′- 13 C]-RIBONUCLEOSIDES FOR INCORPORATION INTO OLIGO-RNA

Y. Saito , A. Nyilas , Luigi A. Agrofoglio

Nucleosides, Nucleotides and Nucleic Acids, 2007, 20 (4-7), pp.937-940. ⟨10.1081/ncn-100002463⟩

Article dans une revue hal-05588810v1

Study of different copper(I) catalysts for the "click chemistry" approach to carbanucleosides

J. Broggi , N. Joubert , Vincent Aucagne , T. Zevaco , S. Berteina-Raboin et al.

Nucleosides, Nucleotides and Nucleic Acids, 2007, 26, pp.779-783

Article dans une revue hal-00275217v1

ANALYSIS OF ANTI-HIV NUCLEOSIDE INHIBITORS BY CAPILLARY ELECTROPHORESIS-ELECTROSPRAY IONIZATION MASS SPECTROMETRY

Luigi A. Agrofoglio , X. Cahours , T. Tran , H. Dessans , C. Kieda et al.

Nucleosides, Nucleotides and Nucleic Acids, 2007, 20 (4-7), pp.375-381. ⟨10.1081/ncn-100002309⟩

Article dans une revue hal-05588817v1

Nucleotide binding to human UMP-CMP kinase using fluorescent derivatives - a screening based on affinity for the UMP-CMP binding site.

Dimitri Topalis , Hiroki Kumamoto , Maria-Fernanda Amaya Velasco , Laurence Dugué , Ahmed Haouz et al.

FEBS Journal, 2007, 274 (14), pp.3704-14. ⟨10.1111/j.1742-4658.2007.05902.x⟩

Article dans une revue pasteur-00166127v1

Cross-Metathesis Mediated Synthesis of New Acyclic Nucleoside Phosphonates

Vincent Roy , Hiroki Kumamoto , Sabine Berteina-Raboin , Steven Nolan , Dimitri Topalis et al.

Nucleosides, Nucleotides and Nucleic Acids, 2007, 26 (10-12), pp.1399-1402. ⟨10.1080/15257770701534196⟩

Article dans une revue hal-05588782v1

Alkyne-Azide Click Chemistry Mediated Carbanucleosides Synthesis

Julie Broggi , Nicolas Joubert , Vincent Aucagne , Sabine Berteina-Raboin , S. Diez-Gonzalez et al.

Nucleosides, Nucleotides and Nucleic Acids, 2007, 26 (10-12), pp.1391-1394. ⟨10.1080/15257770701534139⟩

Article dans une revue hal-04678703v1

Supported Synthesis and Functionnalization of 2″-Deoxyuridine by Suzuki-Miyaura Cross-Coupling

Saïd El Kazzouli , Sabine Berteina-Raboin , Luigi A. Agrofoglio

Nucleosides, Nucleotides and Nucleic Acids, 2007, 26 (10-12), pp.1395-1398. ⟨10.1080/15257770701534170⟩

Article dans une revue hal-05588783v1

SYNTHESIS OF CARBOCYCLIC PHOSPHONONUCLEOSIDES

B. Legeret , Z. Sarakauskaite , F. Pradaux , Y. Saito , S. Tumkevicius et al.

Nucleosides, Nucleotides and Nucleic Acids, 2007, 20 (4-7), pp.661-664. ⟨10.1081/NCN-100002345⟩

Article dans une revue hal-05588814v1

SYNTHESIS OF CARBOCYCLIC PHOSPHONONUCLEOSIDES

B. Légeret , Z. Sarakauskaite , F. Pradaux , Y. Saito , S. Tumkevicius et al.

Nucleosides, Nucleotides and Nucleic Acids, 2007, 20 (4-7), pp.661-664. ⟨10.1081/NCN-100002345⟩

Article dans une revue hal-02061990v1

Looking for new pyrimidine acyclic nucleotide analogues designed for phosphorylation by human ump-cmp kinase.

Dimitri Topalis , Hiroki Kumamoto , Julie a C Alexandre , Laurence Dugué , Sylvie Pochet et al.

Nucleosides, Nucleotides and Nucleic Acids, 2007, 26 (10), pp.1369-73. ⟨10.1080/15257770701533982⟩

Article dans une revue pasteur-00202298v1

Alkyne-Azide Click Chemistry Mediated Carbanucleosides Synthesis

Julie Broggi , Nicolas Joubert , Vincent Aucagne , Sabine Berteina-Raboin , S. Diez-Gonzalez et al.

Nucleosides, Nucleotides and Nucleic Acids, 2007, 26 (10-12), pp.1391-1394. ⟨10.1080/15257770701534139⟩

Article dans une revue hal-02086003v1

An Overview of Diazine Nucleoside Analogues

Luigi A. Agrofoglio

Current Organic Chemistry, 2006, 10 (3), pp.333-362. ⟨10.2174/138527206775473850⟩

Article dans une revue istex hal-05588787v1

Analysis and validation of the phosphorylated metabolites of two anti‐human immunodeficiency virus nucleotides (stavudine and didanosine) by pressure‐assisted CE‐ESI‐MS/MS in cell extracts: Sensitivity enhancement by the use of perfluorinated acids and alcohols as coaxial sheath‐liquid make‐up constituents

Vincent Bezy , Patrick Chaimbault , Philippe Morin , Steve Unger , Marie‐charlotte Bernard et al.

Electrophoresis, 2006, 27 (12), pp.2464-2476. ⟨10.1002/elps.200500850⟩

Article dans une revue istex hal-05588786v1

Efficient synthesis of various acycloalkenyl derivatives of pyrimidine using cross-metathesis and Pd(0) methodologies

Franck Amblard , Steven Nolan , Raymond Schinazi , Luigi A. Agrofoglio

Tetrahedron, 2005, 61 (3), pp.537-544. ⟨10.1016/j.tet.2004.11.019⟩

Article dans une revue hal-05588793v1

Efficient Pd(0)-catalyzed synthesis of 1,2,3-triazolo-3′-deoxycarbanucleosides and their analogues

Nicolas Joubert , Raymond Schinazi , Luigi A. Agrofoglio

Tetrahedron, 2005, 61 (49), pp.11744-11750. ⟨10.1016/j.tet.2005.09.034⟩

Article dans une revue istex hal-05588788v1

Metathesis strategy in nucleoside chemistry

Franck Amblard , Steven Nolan , Luigi A. Agrofoglio

Tetrahedron, 2005, 61 (30), pp.7067-7080. ⟨10.1016/j.tet.2005.04.040⟩

Article dans une revue istex hal-05588791v1

Synthesis of 5-haloethynyl- and 5-(1,2-dihalo)vinyluracil nucleosides: Antiviral activity and cellular toxicity

Vanessa Escuret , Vincent Aucagne , Nicolas Joubert , David Durantel , Kimberly Rapp et al.

Bioorganic and Medicinal Chemistry, 2005, 13 (21), pp.6015-6024. ⟨10.1016/j.bmc.2005.06.021⟩

Article dans une revue istex hal-02086013v1

Synthesis and antiviral activity of novel acyclic nucleosides in the 5-alkynyl- and 6-alkylfuro[2,3-d]pyrimidine series

Franck Amblard , Vincent Aucagne , Pierre Guenot , Raymond Schinazi , Luigi Agrofoglio

Bioorganic and Medicinal Chemistry, 2005, 13 (4), pp.1239-1248. ⟨10.1016/j.bmc.2004.11.057⟩

Article dans une revue istex hal-02086014v1

Olefin Metathesis Route to Antiviral Nucleosides

Luigi A. Agrofoglio , Steven Nolan

Current Topics in Medicinal Chemistry, 2005, 5 (15), pp.1541-1558. ⟨10.2174/156802605775009739⟩

Article dans une revue istex hal-05588790v1

Highly Efficient AgNO3-Catalyzed Preparation of Substituted Furanopyrimidine Nucleosides [cf. (III)].

Vincent Aucagne , Franck Amblard , Luigi Agrofoglio

ChemInform, 2005, 36 (18), ⟨10.1002/chin.200518181⟩

Article dans une revue istex hal-02086027v1

Simultaneous analysis of several antiretroviral nucleosides in rat-plasma by high-performance liquid chromatography with UV using acetic acid/hydroxylamine bufferTest of this new volatile medium-pH for HPLC–ESI-MS/MS

V Bezy , P Morin , P Couerbe , G Leleu , Luigi A. Agrofoglio

Journal of Chromatography B - Analytical Technologies in the Biomedical and Life Sciences, 2005, 821 (2), pp.132-143. ⟨10.1016/j.jchromb.2005.04.003⟩

Article dans une revue istex hal-05588792v1

Highly Efficient AgNO 3 -Catalyzed Preparation of Substituted Furano­pyrimidine Nucleosides

Vincent Aucagne , Franck Amblard , Luigi A. Agrofoglio

SYNLETT, 2004, 13, pp.2406-2408. ⟨10.1055/s-2004-831330⟩

Article dans une revue hal-05588795v1

Palladium-Catalyzed Synthesis of Uridines on Polystyrene-Based Solid Supports

Vincent Aucagne , Sabine Berteina-Raboin , Pierre Guenot , Luigi Agrofoglio

Journal of Combinatorial Chemistry, 2004, 6 (5), pp.717-723. ⟨10.1021/cc049976o⟩

Article dans une revue hal-02086022v1

Synthesis of l-cyclopentenyl nucleosides using ring-closing metathesis and palladium-mediated allylic alkylation methodologies

Luigi A. Agrofoglio , Franck Amblard , Steven Nolan , Steve Charamon , Isabelle Gillaizeau et al.

Tetrahedron, 2004, 60 (38), pp.8397-8404. ⟨10.1016/j.tet.2004.07.009⟩

Article dans une revue hal-05588796v1

Straightforward Synthesis of Labeled and Unlabeled Pyrimidine d4Ns via 2′,3′-Diyne seco Analogues through Olefin Metathesis Reactions

Isabelle Gillaizeau , Irene m. Lagoja , Steve p. Nolan , Vincent Aucagne , Jef Rozenski et al.

European Journal of Organic Chemistry, 2003, 2003 (4), pp.666-671. ⟨10.1002/ejoc.200390107⟩

Article dans une revue istex hal-02086029v1

Liquid chromatographic separation of phosphoramidate diastereomers on a polysaccharide-type chiral stationary phase

Nathalie Mesplet , Yoshio Saito , Philippe Morin , Luigi A. Agrofoglio

Journal of Chromatography A, 2003, 983 (1-2), pp.115-124. ⟨10.1016/S0021-9673(02)01738-7⟩

Article dans une revue istex hal-05588801v1

A new route to acyclic nucleosides via palladium-mediated allylic alkylation and cross-metathesis

Franck Amblard , Steven Nolan , Isabelle Gillaizeau , Luigi A. Agrofoglio

Tetrahedron Letters, 2003, 44 (51), pp.9177-9180. ⟨10.1016/j.tetlet.2003.10.029⟩

Article dans une revue hal-05588799v1

HPLC and mass spectrometry analysis of the enzymatic hydrolysis of anti-HIV pronucleotide diastereomers

Nathalie Mesplet , Yoshio Saito , Philippe Morin , Luigi A. Agrofoglio

Bioorganic Chemistry, 2003, 31 (3), pp.237-247. ⟨10.1016/S0045-2068(03)00035-X⟩

Article dans une revue istex hal-05588800v1

Palladium-Assisted Routes to Nucleosides

Luigi A. Agrofoglio , Isabelle Gillaizeau , Yoshio Saito

Chemical Reviews, 2003, 103 (5), pp.1875-1916. ⟨10.1021/cr010374q⟩

Article dans une revue hal-05588797v1

Synthesis of a Novel Heterocyclic System: 2H-2,3,5,6,9-Pentaazabenz[cd]azulene

Sigitas Tumkevicius , Luigi Agrofoglio , Andrius Kaminskas , Gintaras Urbelis , Thomas Zevaco et al.

Chemistry of Heterocyclic Compounds, 2002, 38 (12), pp.1531-1532. ⟨10.1023/A:1022662015619⟩

Article dans une revue hal-05588806v1

Chemical synthesis of 13C labeled anti-HIV nucleosides as mass-internal standards

Yoshio Saito , Thomas Zevaco , Luigi A. Agrofoglio

Tetrahedron, 2002, 58 (47), pp.9593-9603. ⟨10.1016/S0040-4020(02)01246-2⟩

Article dans une revue hal-05588803v1

Analysis of intracellular didanosine triphosphate at sub-ppb level using LC-MS/MS

Xavier Cahours , Thanh Thu Tran , Nathalie Mesplet , Claudine Kieda , Philippe Morin et al.

Journal of Pharmaceutical and Biomedical Analysis, 2001, 26 (5-6), pp.819-827. ⟨10.1016/s0731-7085(01)00457-5⟩

Article dans une revue istex hal-05588816v1

Synthesis of isotopically labeled d-[1′-13C]ribonucleoside phosphoramidites

Yoshio Saito , Agnès Nyilas , Luigi A. Agrofoglio

Carbohydrate Research, 2001, 331 (1), pp.83-90. ⟨10.1016/s0008-6215(00)00327-x⟩

Article dans une revue hal-05588807v1

Enantioselective synthesis of carba- l -furanose precursors of carbanucleosides, using ring-closing metathesis

Isabelle Gillaizeau , Steve Charamon , Luigi A. Agrofoglio

Tetrahedron Letters, 2001, 42 (50), pp.8817-8819. ⟨10.1016/S0040-4039(01)01905-0⟩

Article dans une revue hal-05588815v1

Simultaneous quantitation of nucleoside HIV-1 reverse transcriptase inhibitors by short-end injection capillary electrochromatography on a β-cyclodextrin-bonded silica stationary phase

Nathalie Mesplet , Philippe Morin , Carole François , Luigi A. Agrofoglio

Journal of Chromatography A, 2001, 927 (1-2), pp.161-168. ⟨10.1016/S0021-9673(01)01063-9⟩

Article dans une revue istex hal-05588811v1

Determination at ppb level of an anti-human immunodeficiency virus nucleoside drug by capillary electrophoresis–electrospray ionization tandem mass spectrometry

Xavier Cahours , Hélène Dessans , Philippe Morin , Michel Dreux , Luigi A. Agrofoglio

Journal of Chromatography A, 2000, 895 (1-2), pp.101-109. ⟨10.1016/s0021-9673(00)00524-0⟩

Article dans une revue istex hal-05588820v1

Determination at ppb level of an anti-human immunodeficiency virus nucleoside drug by capillary electrophoresis–electrospray ionization tandem mass spectrometry

Xavier Cahours , Hélène Dessans , Philippe Morin , Michel Dreux , Luigi Agrofoglio

Journal of Chromatography A, 2000, 895 (1-2), pp.101-109. ⟨10.1016/s0021-9673(00)00524-0⟩

Article dans une revue istex hal-03298652v1

Synthesis of 5′-Thioalkyl, Sulfoxide and Sulfone Pyrimidine Nucleosides

Luigi A. Agrofoglio , F. Girard , F. Fleury , S. Léonce

Nucleosides and Nucleotides, 1999, 18 (4-5), pp.599-600. ⟨10.1080/15257779908041508⟩

Article dans une revue hal-05588823v1

Chiral Synthesis of Carbocyclic Analogues of l -ribofuranosides

Peiyuan Wang , Luigi A. Agrofoglio , M. Gary Newton , Chung Chu

Journal of Organic Chemistry, 1999, 64 (11), pp.4173-4178. ⟨10.1021/jo9812330⟩

Article dans une revue hal-05588822v1

Enantiomeric synthesis of nucleosides

Luigi A. Agrofoglio , Christine Demaison , Loïc Toupet

Tetrahedron, 1999, 55 (26), pp.8075-8082. ⟨10.1016/S0040-4020(99)00424-X⟩

Article dans une revue istex hal-05588826v1

Stereoselective Synthesis of Carbocyclic α-L-Homonucleosides

Luigi A. Agrofoglio , F. Girard , C. Demaison , M-G. Lee , P. Roingeard et al.

Nucleosides and Nucleotides, 1999, 18 (4-5), pp.601-602. ⟨10.1080/15257779908041509⟩

Article dans une revue hal-05588825v1

Stereoselective synthesis of α-l-bicarbocyclic nucleosides as potential antiviral drugs

Christine Demaison , Christophe Hourioux , Philippe Roingeard , Luigi A. Agrofoglio

Tetrahedron Letters, 1998, 39 (50), pp.9175-9178. ⟨10.1016/S0040-4039(98)02137-6⟩

Article dans une revue istex hal-05588831v1

Asymmetric synthesis of L-cyclopentyl carbocyclic nucleosides

Peiyuan Wang , Luigi A. Agrofoglio , M. Gary Newton , Chung Chu

Tetrahedron Letters, 1997, 38 (24), pp.4207-4210. ⟨10.1016/S0040-4039(97)00898-8⟩

Article dans une revue istex hal-05588852v1

Synthesis of Some 5′-Thiopentofuranosylpyrimidines as Potential Anti-tumor Agents.

Frédéric Girard , Stephane Leonce , Luigi A. Agrofoglio

Tetrahedron Letters, 1997, 38 (43), pp.7535-7538. ⟨10.1016/S0040-4039(97)10025-9⟩

Article dans une revue istex hal-05588853v1

A multigram, stereoselective synthesis of d-[13C5]ribose from d-[13C6]glucose and its conversion into [13C5]nucleosides

Luigi A. Agrofoglio , Jean-Claude Jacquinet , Gérard Lancelot

Tetrahedron Letters, 1997, 38 (8), pp.1411-1412. ⟨10.1016/S0040-4039(97)00080-4⟩

Article dans une revue istex hal-05588855v1

Inhibition of human immunodeficiency virus type 1 reverse transcriptase by the 5'-triphosphate beta enantiomers of cytidine analogs

A Faraj , Luigi A. Agrofoglio , J Wakefield , S Mcpherson , C Morrow et al.

Antimicrobial Agents and Chemotherapy, 1994, 38 (10), pp.2300-2305. ⟨10.1128/aac.38.10.2300⟩

Article dans une revue hal-05588858v1

Synthesis of carbocyclic nucleosides

Luigi A. Agrofoglio , Edouard Suhas , Audrey Farese , Roger Condom , S. Richard Challand et al.

Tetrahedron, 1994, 50 (36), pp.10611-10670. ⟨10.1016/S0040-4020(01)89258-9⟩

Article dans une revue istex hal-05588857v1

Synthesis of Three New Carbocyclic Analogues of 3′-Deoxy Purine Ribonucleosides

Luigi A. Agrofoglio , Roger Condom , Roger Guedj , S. Richard Challand , John Selway

Nucleosides and Nucleotides, 1994, 13 (5), pp.1147-1160. ⟨10.1080/15257779408011885⟩

Article dans une revue hal-05588860v1

Synthesis of a new exocyclic amino carbocyclic nucleoside with potential antiviral activity.

Luigi A. Agrofoglio , Roger Condom , Roger Guedj , Richard Challand , John Selway

Tetrahedron Letters, 1993, 34 (39), pp.6271-6272. ⟨10.1016/S0040-4039(00)73729-4⟩

Article dans une revue istex hal-05588861v1

Steric control of the epoxidation of 1-hydroxymethyl-3-cyclopentene using aryl or silyl hydroxyl protecting groups.

Luigi A. Agrofoglio , Roger Condom , Roger Guedj

Tetrahedron Letters, 1992, 33 (38), pp.5503-5504. ⟨10.1016/S0040-4039(00)61128-0⟩

Article dans une revue istex hal-05588862v1

Discovery and characterization of inhibitors of the DNA repair enzymes hNEIL1 and hOGG1, pertinent therapeutic targets for cancer therapy

J. Cros , F. Coste , S. Goffinont , Virginie Nadan , V. Roy et al.

Laboratoire International Associé, Jun 2019, Varsovie, Poland

Communication dans un congrès hal-02903108v1

Small molecule inhibitors of the human DNA glycosylases hOGG1 and NEIL1, pertinent therapeutic targets in cancer and neurodegenerative disease therapies

J. Cros , F. Coste , Z. Tber , S. Goffinont , Virginie Nadan et al.

25th Young Research Fellows Meeting, Mar 2018, Orléans, France

Communication dans un congrès hal-02903084v1

Real-time study of adenosine-5’ monophosphate adsorption with a Love wave sensor based on molecularly imprinted polymer

Naïma Lebal , Hamida Hallil , Vincent Raimbault , Jean-Luc Lachaud , Aleksandra Krstulja et al.

The 9th International Conference on Molecular Imprinting (MIP 2016), Jun 2016, Lund, Sweden. pp.P2-56

Communication dans un congrès hal-01393054v1

Direct access to fluorine containing 3,3-disubstituted oxetanes and alkelidenes oxetanes

Romain Laporte , Anais Prunier , Emmanuel Pfund , Vincent Roy , Luigi A Agrofoglio et al.

21th Internationnal Symposium on Fluorine Chemistry, Aug 2015, Come, Italy

Communication dans un congrès hal-01829958v1

Real time detection of nucleosides analogs in liquid medium with molecularly imprinted polymer coated Love wave sensor

Naïma Lebal , Hamida Hallil , Jean-Luc Lachaud , Vincent Raimbault , Corinne Dejous et al.

15th International Meeting on Chemical Sensors (IMCS 2014), Mar 2014, Buenos Aires, Argentina. 2p

Communication dans un congrès hal-00938314v1

Molecularly imprinted polymer coated Love wave sensor for real time detection of nucleosides analogs in liquid medium

Naïma Lebal , Hamida Hallil , Jean-Luc Lachaud , Vincent Raimbault , Corinne Dejous et al.

Biosensors, May 2014, Melbourne, Australia

Communication dans un congrès hal-00954368v1

Association of a Love wave sensor to thin film molecularly imprinted polymers for nucleosides analogs detection

Naïma Lebal , Hamida Hallil , Corinne Dejous , Aleksandra Kristulja , Raphaël Delépée et al.

The IEEE International Conference on Nano/Micro Engineered and Molecular Systems (IEEE NEMS 2013), Apr 2013, Suzhou, China. pp.550-553, ⟨10.1109/NEMS.2013.6559790⟩

Communication dans un congrès hal-00772051v1

Nucleosides analogs recognition by Molecularly Imprinted Polymer- coated Love wave sensor

Naïma Lebal , Hamida Hallil , Corinne Dejous , Bernard Plano , Raphaël Delépée et al.

2013 Symposium on Microelectronics Technology and Devices (SBMicro 2013), Sep 2013, Curitiba, Brazil. pp.28-31

Communication dans un congrès hal-00938251v1

Love wave sensor based on thin film molecularly imprinted polymer : MIP layer morphology and nucleosides analogs detection

Nima Omar-Aouled , Hamida Hallil , Bernard Plano , Raphaël Delépée , Luigi A. Agrofoglio et al.

IEEE SENSORS 2013, Nov 2013, Baltimore, United States. ID 7218, 4p

Communication dans un congrès hal-00938274v1

SH-SAW Sensing System based on thin film molecularly imprinted polymer: Study of Volatile organic compounds adsorption

Hamida Hallil , Nima Omar-Aouled , Bernard Plano , Raphaël Delépée , Luigi A. Agrofoglio et al.

2013 Symposium on Microelectronics Technology and Devices (SBMicro 2013), Sep 2013, Curitiba, Brazil. pp.32-35

Communication dans un congrès hal-00938255v1

Association of a Love wave sensor and thin film of molecularly imprinted polymers for nucleotide detection

Naïma Lebal , Hamida Hallil , Corinne Dejous , Aleksandra Krstulja , Raphaël Delépée et al.

Ecole Thématique NAMIS (International Research Group -Nano Micro Systems-), Sep 2012, Tokyo, Japan

Communication dans un congrès hal-00954371v1

Molecularly imprinted polymer thin film applied to a Love wave sensor

Nima Omar-Aouled , Hamida Hallil , Raphaël Delépée , Luigi A. Agrofoglio , Dominique Rebière et al.

Ecole Thématique NAMIS (International Research Group -Nano Micro Systems-), Sep 2012, Tokyo, Japan

Communication dans un congrès hal-00954370v1

Study of gaseous compounds adsorption with a Love wave sensor based on molecularly imprinted polymer thin film

Nima Omar-Aouled , Naïma Lebal , Hamida Hallil , Raphaël Delépée , Luigi A. Agrofoglio et al.

8e Journées Maghreb-Europe sur les Matériaux et leurs Applications aux Dispositifs Capteurs (MADICA 2012), Nov 2012, Sousse, Tunisia

Communication dans un congrès hal-00772045v1

Synthesis of selected nucleosides against RNA viruses

Luigi A. Agrofoglio , Vincent Roy , Mathias Brouillard , Evan Saillard

Synthesis and Applications of Carbohydrates, Lipids and Steroids, 2025, 9781032568607

Chapitre d'ouvrage hal-05588875v1

CHAPTER 3. Molecularly Imprinted Polymers-based Separation and Sensing of Nucleobases, Nucleosides, Nucleotides and Oligonucleotides

Patrick Favetta , Mohamed G. Ayari , Luigi Agrofoglio

Wlodzimierz Kutner; Piyush Sindhu Sharma. Molecularly Imprinted Polymers for Analytical Chemistry Applications, Royal Society of Chemistry, pp.65-123, 2018, Polymer Chemistry Series, 978-1-78801-047-4. ⟨10.1039/9781788010474-00065⟩

Chapitre d'ouvrage hal-03856090v1

Molecularly imprinted polymers based separation and sensing of nucleobases, nucleosides, nucleotides and oligonucleotides

Luigi A. Agrofoglio , Patrick Favetta , Ghazi Ayari

Molecularly Imprinted Polymers for Analytical Chemistry Applications, 2018, 978-1-78262-647-3

Chapitre d'ouvrage hal-05588880v1

Suzuki-Miyaura cross-coupling as a synthetic tool for nucleoside and nucleotide modifications - Chapter 3

Luigi A. Agrofoglio , Nicolas G. Biteau , Vincent Hervin , Vincent Roy

Palladium-Catalyzed Modification of Nucleosides, Nucleotides and Oligonucleotides, 2018, 9780128112939

Chapitre d'ouvrage hal-05588883v1

Nucleosides Modified at the Base Moiety

Luigi A. Agrofoglio , Ozkan Sari , Vincent Roy

Chemical Synthesis of Nucleoside Analogues, 2008

Chapitre d'ouvrage hal-05588890v1

Synthesis and Biological Activity of Selected Carbocyclic Nucleosides

Luigi A. Agrofoglio , Adam Mieczkowski

Modifed Nucleosides in Biochemistry, Biotechnology and Medecine, 2008, 978-3-527-31820

Chapitre d'ouvrage hal-05588891v1