Magalie LECOURTOIS

Publications

Article dans une revue (29)

Soluble SorLA in CSF, a novel biomarker to explore disrupted trafficking of SorLA protein in Alzheimer disease Romain Castelot,Aline Zarea,David Wallon,Anne Rovelet-Lecrux,Catherine Schrammet al. Alzheimer's Research and Therapy, 2025, 17 (1), pp.100. ⟨10.1186/s13195-025-01748-0⟩ Article dans une revue hal-05060515v1
Upstream open reading frame-introducing variants in patients with primary familial brain calcification Anne Rovelet-Lecrux,Antoine Bonnevalle,Olivier Quenez,Wandrille Delcroix,Kévin Cassinariet al. European Journal of Human Genetics, 2024, 32 (7), pp.779-785. ⟨10.1038/s41431-024-01580-4⟩ Article dans une revue hal-04659594v1
Generation of 17q21.31 duplication iPSC-derived neurons as a model for primary tauopathies Laetitia Miguel,Anne Rovelet-Lecrux,Pascal Chambon,Géraldine Joly-Helas,Stéphane Rousseauet al. Stem Cell Research, 2022, 61, pp.102762. ⟨10.1016/j.scr.2022.102762⟩ Article dans une revue hal-03622429v1
uORF‐introducing variants in the 5′UTR of the NIPBL gene as a cause of Cornelia de Lange syndrome Juliette Coursimault,Anne Rovelet-Lecrux,Kévin Cassinari,Elise Brischoux-Boucher,Pascale Saugier-Veberet al. Human Mutation, 2022, 43 (9), pp.1239-1248. ⟨10.1002/humu.24384⟩ Article dans une revue hal-03822689v1
Impaired SorLA maturation and trafficking as a new mechanism for SORL1 missense variants in Alzheimer disease Anne Rovelet-Lecrux,Sebastien Feuillette,Laetitia Miguel,Catherine Schramm,Ségolène Pernetet al. Acta Neuropathologica Communications, 2021, 9, ⟨10.1186/s40478-021-01294-4⟩ Article dans une revue hal-03512083v1
A Connected Network of Interacting Proteins Is Involved in Human-Tau Toxicity in Drosophila Sébastien Feuillette,Camille Charbonnier,Thierry Frebourg,Dominique Campion,Magalie Lecourtois Frontiers in Neuroscience, 2020, 14, ⟨10.3389/fnins.2020.00068⟩ Article dans une revue hal-02503970v1
Moderate Overexpression of Tau in Drosophila Exacerbates Amyloid-β-Induced Neuronal Phenotypes and Correlates with Tau Oligomerization Laetitia Miguel,Thierry Frébourg,Dominique Campion,Magalie Lecourtois Journal of Alzheimer's Disease, 2020, pp.1-11. ⟨10.3233/JAD-190906⟩ Article dans une revue hal-02484269v1
A Connected Network of Interacting Proteins Is Involved in Human-Tau Toxicity in Drosophila Sébastien Feuillette,Camille Charbonnier,Thierry Frebourg,Dominique Campion,Magalie Lecourtois Frontiers in Neuroscience, 2020, 14, ⟨10.3389/fnins.2020.00068⟩ Article dans une revue hal-03080080v1
Detection of all adult Tau isoforms in a 3D culture model of iPSC-derived neurons Laetitia Miguel,Anne Rovelet-Lecrux,Maxime Feyeux,Thierry Frebourg,Pierre Nassoyet al. Stem Cell Research, 2019, 40, pp.101541. ⟨10.1016/j.scr.2019.101541⟩ Article dans une revue hal-03038792v1
Identification of TCERG1 as a new genetic modulator of TDP-43 production in Drosophila Marine Pons,Silvia Prieto,Laetitia Miguel,Thierry Frébourg,Dominique Campionet al. Acta Neuropathologica Communications, 2018, 6 (1), ⟨10.1186/s40478-018-0639-5⟩ Article dans une revue hal-02330484v1
FTLD/ALS-linked TDP-43 mutations do not alter TDP-43’s ability to self-regulate its expression in Drosophila Laetitia Miguel,Tracey Avequin,Marine Pons,Thierry Frébourg,Dominique Campionet al. Brain Research, 2018, 1695, pp.1-9. ⟨10.1016/j.brainres.2018.05.021⟩ Article dans une revue hal-02330526v1
Enhancing Mitofusin/Marf ameliorates neuromuscular dysfunction in Drosophila models of TDP-43 proteinopathies Bilal Khalil,Marie-Jeanne Cabirol-Pol,Laetitia Miguel,Alexander J. Whitworth,Magalie Lecourtoiset al. Neurobiology of Aging, 2017, 54, pp.71--83. ⟨10.1016/j.neurobiolaging.2017.02.016⟩ Article dans une revue hal-01994093v1
Splicing factors act as genetic modulators of TDP-43 production in a new autoregulatory TDP-43 Drosophila model Marine Pons,Laetitia Miguel,Camille Miel,Tracey Avequin,François Jugeet al. Human Molecular Genetics, 2017, 26 (17), pp.3396-3408. ⟨10.1093/hmg/ddx229⟩ Article dans une revue hal-02330529v1
Neuron-to-Neuron Transfer of FUS in Drosophila Primary Neuronal Culture Is Enhanced by ALS-Associated Mutations Sébastien Feuillette,Morgane Delarue,Gaëtan Riou,Anne-Lise Gaffuri,Jane Wuet al. Journal of Molecular Neuroscience, 2017, 62 (1), pp.114-122. ⟨10.1007/s12031-017-0908-y⟩ Article dans une revue hal-02330532v1
Protein Kinase CK-1 Inhibitors As New Potential Drugs for Amyotrophic Lateral Sclerosis Irene Salado,Miriam Redondo,Murilo Bello,Concepción Pérez,Nicole Liachkoet al. Journal of Medicinal Chemistry, 2014, 57 (6), pp.2755-2772. ⟨10.1021/jm500065f⟩ Article dans une revue hal-02330558v1
Accumulation of insoluble forms of FUS protein correlates with toxicity in Drosophila Laetitia Miguel,Tracey Avequin,Morgane Delarue,Sébastien Feuillette,Thierry Frebourget al. Neurobiology of Aging, 2012, 33 (5), pp.1008.e1-1008.e15. ⟨10.1016/j.neurobiolaging.2011.10.008⟩ Article dans une revue istex hal-02332201v1
Lack of miRNA Misregulation at Early Pathological Stages in Drosophila Neurodegenerative Disease Models Anita Reinhardt,Sébastien Feuillette,Marlène Cassar,Céline Callens,Hélène Thomassinet al. Frontiers in Genetics, 2012, 3 (226), 14 p. ⟨10.3389/fgene.2012.00226⟩ Article dans une revue hal-02331191v1
Trisomy for synaptojanin1 in Down syndrome is functionally linked to the enlargement of early endosomes Jack-Christophe Cossec,Jeremie Lavaur,Diego Berman,Isabelle Rivals,Alexander Hoischenet al. Human Molecular Genetics, 2012, 21 (14), pp.3156-3172. ⟨10.1093/hmg/dds142⟩ Article dans une revue hal-02332572v1
Lack of miRNA Misregulation at Early Pathological Stages in Drosophila Neurodegenerative Disease Models Anita Reinhardt,Sébastien Feuillette,Marlène Cassar,Céline Callens,Hélène Thomassin-Bourrelet al. Frontiers in Genetics, 2012, 3, pp.226. ⟨10.3389/fgene.2012.00226⟩ Article dans une revue hal-01537142v1
Both cytoplasmic and nuclear accumulations of the protein are neurotoxic in Drosophila models of TDP-43 proteinopathies Laetitia Miguel,Thierry Frebourg,Dominique Campion,Magalie Lecourtois Neurobiology of Disease, 2011, 41 (2), pp.398-406. ⟨10.1016/j.nbd.2010.10.007⟩ Article dans une revue istex hal-02332578v1
Important neuronal toxicity of microtubule-bound Tau in vivo in Drosophila Yasmina Talmat-Amar,Yoan Arribat,Christelle Redt-Clouet,Sébastien Feuillette,Anne-Laure Bougeet al. Human Molecular Genetics, 2011, 20 (19), pp.3738-3745. ⟨10.1093/hmg/ddr290⟩ Article dans une revue hal-02332575v1
Filamin-A and Myosin VI colocalize with fibrillary Tau protein in Alzheimer's disease and FTDP-17 brains Sébastien Feuillette,Vincent Deramecourt,Annie Laquérriere,Charles Duyckaerts,Marie-Bernadette Delisleet al. Brain Research, 2010, 1345, pp.182-189. ⟨10.1016/j.brainres.2010.05.007⟩ Article dans une revue istex hal-02329958v1
Drosophila models of human tauopathies indicate that Tau protein toxicity in vivo is mediated by soluble cytosolic phosphorylated forms of the protein Sébastien Feuillette,Laetitia Miguel,Thierry Frebourg,Dominique Campion,Magalie Lecourtois Journal of Neurochemistry, 2010, 113 (4), pp.895-903. ⟨10.1111/j.1471-4159.2010.06663.x⟩ Article dans une revue hal-02332582v1
Human lissencephaly with cerebellar hypoplasia due to mutations in TUBA1A: expansion of the foetal neuropathological phenotype Magalie Lecourtois,Karine Poirier,Gaëlle Friocourt,Xavier Jaglin,Alice Goldenberget al. Acta Neuropathologica, 2010, 119 (6), pp.779-789. ⟨10.1007/s00401-010-0684-z⟩ Article dans une revue istex hal-02332580v1
Partial deletion of the MAPT gene: A novel mechanism of FTDP-17 Anne Rovelet-Lecrux,Magalie Lecourtois,Catherine Thomas-Antérion,Isabelle Le Ber,Alexis Briceet al. Human Mutation, 2009, 30 (4), pp.E591-E602. ⟨10.1002/humu.20979⟩ Article dans une revue istex hal-02332588v1
Cytoskeleton proteins are modulators of mutant tau-induced neurodegeneration in Drosophila Olivier Blard,Sébastien Feuillette,Jacqueline Bou,Boris Chaumette,Thierry Frebourget al. Human Molecular Genetics, 2007, 16 (5), pp.555-566. ⟨10.1093/hmg/ddm011⟩ Article dans une revue hal-02332593v1
Inhibition of proteasome and Shaggy/Glycogen synthase kinase-3β kinase prevents clearance of phosphorylated tau inDrosophila Olivier Blard,Thierry Frebourg,Dominique Campion,Magalie Lecourtois Journal of Neuroscience Research, 2006, 84 (5), pp.1107-1115. ⟨10.1002/jnr.21006⟩ Article dans une revue istex hal-02332595v1
Tau is not normally degraded by the proteasome Sébastien Feuillette,Olivier Blard,Magalie Lecourtois,Thierry Frebourg,Dominique Campionet al. Journal of Neuroscience Research, 2005, 80 (3), pp.400-405. ⟨10.1002/jnr.20414⟩ Article dans une revue istex hal-02332598v1
Wingless Capture by Frizzled and Frizzled2 in Drosophila Embryos Magalie Lecourtois,Cyrille Alexandre,Laurence Dubois,Jean-Paul Vincent Developmental Biology, 2001, 235 (2), pp.467-475. ⟨10.1006/dbio.2001.0320⟩ Article dans une revue hal-02335777v1