Magalie LECOURTOIS

29
Documents

Publications

Publications

Soluble SorLA in CSF, a novel biomarker to explore disrupted trafficking of SorLA protein in Alzheimer disease

Romain Castelot , Aline Zarea , David Wallon , Anne Rovelet-Lecrux , Catherine Schramm et al.
Alzheimer's Research and Therapy, 2025, 17 (1), pp.100. ⟨10.1186/s13195-025-01748-0⟩
Article dans une revue hal-05060515 v1
Image document

Upstream open reading frame-introducing variants in patients with primary familial brain calcification

Anne Rovelet-Lecrux , Antoine Bonnevalle , Olivier Quenez , Wandrille Delcroix , Kévin Cassinari et al.
European Journal of Human Genetics, 2024, 32 (7), pp.779-785. ⟨10.1038/s41431-024-01580-4⟩
Article dans une revue hal-04659594 v1

uORF‐introducing variants in the 5′UTR of the NIPBL gene as a cause of Cornelia de Lange syndrome

Juliette Coursimault , Anne Rovelet-Lecrux , Kévin Cassinari , Elise Brischoux-Boucher , Pascale Saugier-Veber et al.
Human Mutation, 2022, 43 (9), pp.1239-1248. ⟨10.1002/humu.24384⟩
Article dans une revue hal-03822689 v1
Image document

Generation of 17q21.31 duplication iPSC-derived neurons as a model for primary tauopathies

Laetitia Miguel , Anne Rovelet-Lecrux , Pascal Chambon , Géraldine Joly-Helas , Stéphane Rousseau et al.
Stem Cell Research, 2022, 61, pp.102762. ⟨10.1016/j.scr.2022.102762⟩
Article dans une revue hal-03622429 v1
Image document

Impaired SorLA maturation and trafficking as a new mechanism for SORL1 missense variants in Alzheimer disease

Anne Rovelet-Lecrux , Sebastien Feuillette , Laetitia Miguel , Catherine Schramm , Ségolène Pernet et al.
Acta Neuropathologica Communications, 2021, 9, ⟨10.1186/s40478-021-01294-4⟩
Article dans une revue hal-03512083 v1

A Connected Network of Interacting Proteins Is Involved in Human-Tau Toxicity in Drosophila

Sébastien Feuillette , Camille Charbonnier , Thierry Frebourg , Dominique Campion , Magalie Lecourtois
Frontiers in Neuroscience, 2020, 14, ⟨10.3389/fnins.2020.00068⟩
Article dans une revue hal-02503970 v1

Moderate Overexpression of Tau in Drosophila Exacerbates Amyloid-β-Induced Neuronal Phenotypes and Correlates with Tau Oligomerization

Laetitia Miguel , Thierry Frébourg , Dominique Campion , Magalie Lecourtois
Journal of Alzheimer's Disease, 2020, pp.1-11. ⟨10.3233/JAD-190906⟩
Article dans une revue hal-02484269 v1
Image document

A Connected Network of Interacting Proteins Is Involved in Human-Tau Toxicity in Drosophila

Sébastien Feuillette , Camille Charbonnier , Thierry Frebourg , Dominique Campion , Magalie Lecourtois
Frontiers in Neuroscience, 2020, 14, ⟨10.3389/fnins.2020.00068⟩
Article dans une revue hal-03080080 v1
Image document

Detection of all adult Tau isoforms in a 3D culture model of iPSC-derived neurons

Laetitia Miguel , Anne Rovelet-Lecrux , Maxime Feyeux , Thierry Frebourg , Pierre Nassoy et al.
Stem Cell Research, 2019, 40, pp.101541. ⟨10.1016/j.scr.2019.101541⟩
Article dans une revue hal-03038792 v1

Identification of TCERG1 as a new genetic modulator of TDP-43 production in Drosophila

Marine Pons , Silvia Prieto , Laetitia Miguel , Thierry Frébourg , Dominique Campion et al.
Acta Neuropathologica Communications, 2018, 6 (1), ⟨10.1186/s40478-018-0639-5⟩
Article dans une revue hal-02330484 v1

FTLD/ALS-linked TDP-43 mutations do not alter TDP-43’s ability to self-regulate its expression in Drosophila

Laetitia Miguel , Tracey Avequin , Marine Pons , Thierry Frébourg , Dominique Campion et al.
Brain Research, 2018, 1695, pp.1-9. ⟨10.1016/j.brainres.2018.05.021⟩
Article dans une revue hal-02330526 v1

Enhancing Mitofusin/Marf ameliorates neuromuscular dysfunction in Drosophila models of TDP-43 proteinopathies

Bilal Khalil , Marie-Jeanne Cabirol-Pol , Laetitia Miguel , Alexander J. Whitworth , Magalie Lecourtois et al.
Neurobiology of Aging, 2017, 54, pp.71--83. ⟨10.1016/j.neurobiolaging.2017.02.016⟩
Article dans une revue hal-01994093 v1

Splicing factors act as genetic modulators of TDP-43 production in a new autoregulatory TDP-43 Drosophila model

Marine Pons , Laetitia Miguel , Camille Miel , Tracey Avequin , François Juge et al.
Human Molecular Genetics, 2017, 26 (17), pp.3396-3408. ⟨10.1093/hmg/ddx229⟩
Article dans une revue hal-02330529 v1

Neuron-to-Neuron Transfer of FUS in Drosophila Primary Neuronal Culture Is Enhanced by ALS-Associated Mutations

Sébastien Feuillette , Morgane Delarue , Gaëtan Riou , Anne-Lise Gaffuri , Jane Wu et al.
Journal of Molecular Neuroscience, 2017, 62 (1), pp.114-122. ⟨10.1007/s12031-017-0908-y⟩
Article dans une revue hal-02330532 v1

Protein Kinase CK-1 Inhibitors As New Potential Drugs for Amyotrophic Lateral Sclerosis

Irene Salado , Miriam Redondo , Murilo Bello , Concepción Pérez , Nicole Liachko et al.
Journal of Medicinal Chemistry, 2014, 57 (6), pp.2755-2772. ⟨10.1021/jm500065f⟩
Article dans une revue hal-02330558 v1

Accumulation of insoluble forms of FUS protein correlates with toxicity in Drosophila

Laetitia Miguel , Tracey Avequin , Morgane Delarue , Sébastien Feuillette , Thierry Frebourg et al.
Neurobiology of Aging, 2012, 33 (5), pp.1008.e1-1008.e15. ⟨10.1016/j.neurobiolaging.2011.10.008⟩
Article dans une revue istex hal-02332201 v1
Image document

Lack of miRNA Misregulation at Early Pathological Stages in Drosophila Neurodegenerative Disease Models

Anita Reinhardt , Sébastien Feuillette , Marlène Cassar , Céline Callens , Hélène Thomassin et al.
Frontiers in Genetics, 2012, 3 (226), 14 p. ⟨10.3389/fgene.2012.00226⟩
Article dans une revue hal-02331191 v1

Lack of miRNA Misregulation at Early Pathological Stages in Drosophila Neurodegenerative Disease Models

Anita Reinhardt , Sébastien Feuillette , Marlène Cassar , Céline Callens , Hélène Thomassin-Bourrel et al.
Frontiers in Genetics, 2012, 3, pp.226. ⟨10.3389/fgene.2012.00226⟩
Article dans une revue hal-01537142 v1

Trisomy for synaptojanin1 in Down syndrome is functionally linked to the enlargement of early endosomes

Jack-Christophe Cossec , Jeremie Lavaur , Diego Berman , Isabelle Rivals , Alexander Hoischen et al.
Human Molecular Genetics, 2012, 21 (14), pp.3156-3172. ⟨10.1093/hmg/dds142⟩
Article dans une revue hal-02332572 v1

Both cytoplasmic and nuclear accumulations of the protein are neurotoxic in Drosophila models of TDP-43 proteinopathies

Laetitia Miguel , Thierry Frebourg , Dominique Campion , Magalie Lecourtois
Neurobiology of Disease, 2011, 41 (2), pp.398-406. ⟨10.1016/j.nbd.2010.10.007⟩
Article dans une revue istex hal-02332578 v1

Important neuronal toxicity of microtubule-bound Tau in vivo in Drosophila

Yasmina Talmat-Amar , Yoan Arribat , Christelle Redt-Clouet , Sébastien Feuillette , Anne-Laure Bouge et al.
Human Molecular Genetics, 2011, 20 (19), pp.3738-3745. ⟨10.1093/hmg/ddr290⟩
Article dans une revue hal-02332575 v1

Filamin-A and Myosin VI colocalize with fibrillary Tau protein in Alzheimer's disease and FTDP-17 brains

Sébastien Feuillette , Vincent Deramecourt , Annie Laquérriere , Charles Duyckaerts , Marie-Bernadette Delisle et al.
Brain Research, 2010, 1345, pp.182-189. ⟨10.1016/j.brainres.2010.05.007⟩
Article dans une revue istex hal-02329958 v1

Drosophila models of human tauopathies indicate that Tau protein toxicity in vivo is mediated by soluble cytosolic phosphorylated forms of the protein

Sébastien Feuillette , Laetitia Miguel , Thierry Frebourg , Dominique Campion , Magalie Lecourtois
Journal of Neurochemistry, 2010, 113 (4), pp.895-903. ⟨10.1111/j.1471-4159.2010.06663.x⟩
Article dans une revue hal-02332582 v1

Human lissencephaly with cerebellar hypoplasia due to mutations in TUBA1A: expansion of the foetal neuropathological phenotype

Magalie Lecourtois , Karine Poirier , Gaëlle Friocourt , Xavier Jaglin , Alice Goldenberg et al.
Acta Neuropathologica, 2010, 119 (6), pp.779-789. ⟨10.1007/s00401-010-0684-z⟩
Article dans une revue istex hal-02332580 v1

Partial deletion of the MAPT gene: A novel mechanism of FTDP-17

Anne Rovelet-Lecrux , Magalie Lecourtois , Catherine Thomas-Antérion , Isabelle Le Ber , Alexis Brice et al.
Human Mutation, 2009, 30 (4), pp.E591-E602. ⟨10.1002/humu.20979⟩
Article dans une revue istex hal-02332588 v1

Cytoskeleton proteins are modulators of mutant tau-induced neurodegeneration in Drosophila

Olivier Blard , Sébastien Feuillette , Jacqueline Bou , Boris Chaumette , Thierry Frebourg et al.
Human Molecular Genetics, 2007, 16 (5), pp.555-566. ⟨10.1093/hmg/ddm011⟩
Article dans une revue hal-02332593 v1

Inhibition of proteasome and Shaggy/Glycogen synthase kinase-3β kinase prevents clearance of phosphorylated tau inDrosophila

Olivier Blard , Thierry Frebourg , Dominique Campion , Magalie Lecourtois
Journal of Neuroscience Research, 2006, 84 (5), pp.1107-1115. ⟨10.1002/jnr.21006⟩
Article dans une revue istex hal-02332595 v1

Tau is not normally degraded by the proteasome

Sébastien Feuillette , Olivier Blard , Magalie Lecourtois , Thierry Frebourg , Dominique Campion et al.
Journal of Neuroscience Research, 2005, 80 (3), pp.400-405. ⟨10.1002/jnr.20414⟩
Article dans une revue istex hal-02332598 v1

Wingless Capture by Frizzled and Frizzled2 in Drosophila Embryos

Magalie Lecourtois , Cyrille Alexandre , Laurence Dubois , Jean-Paul Vincent
Developmental Biology, 2001, 235 (2), pp.467-475. ⟨10.1006/dbio.2001.0320⟩
Article dans une revue hal-02335777 v1