Mai Nguyen Chi

Présentation

Mai NGUYEN-CHI, Ph.D , CRCN CNRS

Born 1981, French nationality – 2 Children

Phone +33 6 40322823 – Email: mai-eva.nguyen-chi@umontpellier.fr

French (Mother tongue), English and Italian (Good knowledge)

Laboratory of Pathogen Host Interactions/UMR5235, Université de Montpellier, France

Research Experience

2016-:CR position at LPHI (DIMNP), CNRS/UMR5235, Montpellier, France,

Team of Dr G. Lutfalla

2013-2015 :Post-doctorat at Institute of Regenerative Medicine and Biotherapies, INSERM/U1183, Montpellier, France, Team of Pr. C. Jorgensen

2011-2013 :Post-doctorat at DIMNP, CNRS/UMR5235, Montpellier, France,

Team of Dr G. Lutfalla

2009-2010 :Post-doctorat at the Australian Regenerative Medicine Institute, Monash University, Melbourne, Australia, Team of Pr. P. Currie

2004-2008 :PhD student at the Centre de Biologie du Développement, CNRS/UMR5547, Toulouse, France, Team of Dr D. Morello and in the University of Firenze, Italy, Team of Pr S. Capaccioli

Education

2004-2008 : PhD studies in Molecular, Cellular and Developmental Biology, University of Toulouse

2003-2004 : Master of Science, Paul Sabatier University

2001-2003 : Undergraduate Degree, Paul Sabatier University

2019-2020: Presently applying for the Habilitation à Diriger des Recherches (HDR), accepted by the University of Montpellier. HDR defense during the winter 2020.

Field of Interest

Onset of Immunity during injuries and bacterial infections in the zebrafish model

Innate immune cell activation, and polarization

Wound healing

Scientific Activity

12 publications inpeer-reviewed journals(including 8 first author, 1 last author, 2 corresponding author),

1 preprint, currently two publications in preparation

4 grants (including 3 as PI): « ANR JCJC 2019 » from Agence Nationale pour la Recherche « Soutien à la recherche 2019 » from the University of Montpellier. « MuseExplore » (2018) from the University of Montpellier Presently preparing an MSCA-ETN application as coordinator.

Supervision: 2 Marie Curie PhDs, 4 Master students

Organizer of the Zebrafish Meeting in Montpellier (every 2 weeks 2013-2015)

Teaching Cell biology (University of Toulouse, 2006), Immunology (University of Montpellier, 2017-2019)

Reviewerfor Fish and Shellfish Immunology and for Zebrafish

Invitations and international conferences

June 2019: Leiden, Netherland, Invited speaker by Annemarie Meijer, Leiden University

June 2019: Wageningen, Netherland, Opponent in a PhD defense at Wageningen University and Research

Nov. 2019: Oslo, Sweden, Invited speaker byGareth Griffiths, Faculty of Mathematics and Natural Sciences

Publications

Article dans une revue (22)

HIV-1 Tat favors the multiplication of Mycobacterium tuberculosis and Toxoplasma by inhibiting clathrin-mediated endocytosis and autophagy Aurélie Rivault,Audrey Bernut,Myriam Ben-Neji,Magali Abrantes,Maxime Jansenet al. PLoS Pathogens, 2025, 21 (9), pp.e1013183. ⟨10.1371/journal.ppat.1013183⟩ Article dans une revue hal-05262587v1
Dynamics of macrophage polarization support $Salmonella$ persistence in a whole living organism Jade Leiba,Tamara Sipka,Christina Begon-Pescia,Matteo Bernardello,Sofiane Tairiet al. eLife, 2024, 13, pp.e89828. ⟨10.7554/eLife.89828⟩ Article dans une revue hal-04467359v2
Molecular Actors of Inflammation and Their Signaling Pathways: Mechanistic Insights from Zebrafish Jade Leiba,Resul Özbilgiç,Liz Hernández,Maria Demou,Georges Lutfallaet al. Biology, 2023, 12 (2), pp.153. ⟨10.3390/biology12020153⟩ Article dans une revue hal-04117474v1
Segmentation-based tracking of macrophages in 2D＋time microscopy movies inside a living animal Seol Ah Park,Tamara Sipka,Zuzana Krivá,Georges Lutfalla,Mai Nguyen-Chiet al. Computers in Biology and Medicine, 2023, 153, pp.106499. ⟨10.1016/j.compbiomed.2022.106499⟩ Article dans une revue hal-04823925v1
Macrophages undergo a behavioural switch during wound healing in zebrafish Tamara Sipka,Seol Ah Park,Resul Ozbilgic,Laurence Balas,Thierry Durandet al. Free Radical Biology and Medicine, 2022, 192, pp.200-212. ⟨10.1016/j.freeradbiomed.2022.09.021⟩ Article dans une revue hal-03794564v1
Ontogenetic Changes in Blood Osmolality During the Postembryonic Development of Zebrafish (&lt;i&gt;Danio rerio&lt;/i&gt;) Guy Charmantier,Mai Nguyen-Chi,Georges Lutfalla Zebrafish, 2022, 19 (1), pp.1-6. ⟨10.1089/zeb.2021.0075⟩ Article dans une revue hal-03841275v1
Preparing sequencing grade RNAs from a small number of FACS-sorted larvae macrophages isolated from enzyme free dissociated zebrafish larvae Christina Begon-Pescia,Stéphanie Boireau,Myriam Boyer-Clavel,Georges Lutfalla,Mai Nguyen-Chi MethodsX, 2022, 9, ⟨10.1016/j.mex.2022.101651⟩ Article dans une revue hal-03834650v1
Damage-Induced Calcium Signaling and Reactive Oxygen Species Mediate Macrophage Activation in Zebrafish Tamara Sipka,Romain Peroceschi,Rahma Hassan-Abdi,Martin Gross,Felix Ellettet al. Frontiers in Immunology, 2021, 12, ⟨10.3389/fimmu.2021.636585⟩ Article dans une revue hal-03334425v1
NRG1/ErbB signalling controls the dialogue between macrophages and neural crest-derived cells during zebrafish fin regeneration Béryl Laplace-Builhé,Audrey Barthelaix,Said Assou,Candice Bohaud,Marine Pratlonget al. Nature Communications, 2021, 12 (1), pp.6336. ⟨10.1038/s41467-021-26422-5⟩ Article dans une revue hal-03646943v1
Occurrence of foamy macrophages during the innate response of zebrafish to trypanosome infections Sem H Jacobs,Eva Dóró,Ffion R Hammond,Mai Nguyen-Chi,Georges Lutfallaet al. eLife, 2021, 10, ⟨10.7554/elife.64520⟩ Article dans une revue hal-03374717v1
Macrophage plasticity is Rac signalling and MMP9 dependant Jana Travnickova,Sandra Nhim,Naoill Abdellaoui,Farida Djouad,Maï Nguyen-Chiet al. Scientific Reports, 2021, 11 (1), pp.10123. ⟨10.1101/614388⟩ Article dans une revue hal-02106150v1
Macrophage image segmentation by Thresholding and subjective surface Method Seol Ah Park,Tamara Sipka,Zuzana Kriva,Martin Ambroz,Michal Kollaret al. Tatra Mountains Mathematical Publications, 2020, ⟨10.2478/tmmp-2020-0007⟩ Article dans une revue hal-02390453v1
Pro‐resolving mediator protectin D1 promotes epimorphic regeneration by controlling immune cell function in vertebrates Mai Nguyen-Chi,Patricia Luz-Crawford,Laurence Balas,Tamara Sipka,Rafael Contreras-Lópezet al. British Journal of Pharmacology, 2020, 177 (17), pp.4055-4073. ⟨10.1111/bph.15156⟩ Article dans une revue hal-02993375v1
Neutrophils use superoxide to control bacterial infection at a distance Quang Tien Phan,Tamara Sipka,Catherine Gonzalez,Jean-Pierre Levraud,Georges Lutfallaet al. PLoS Pathogens, 2018, 14 (7), pp.e1007157. ⟨10.1371/journal.ppat.1007157⟩ Article dans une revue hal-02086655v1
TNF signaling and macrophages govern fin regeneration in zebrafish larvae Mai Nguyen-Chi,Béryl Laplace-Builhé,Jana Travnickova,Patricia Luz-Crawford,Gautier Tejedoret al. Cell Death and Disease, 2017, 8, pp.e2979. ⟨10.1038/cddis.2017.374⟩ Article dans une revue hal-02086729v1
Mycobacterium abscessus-Induced Granuloma Formation Is Strictly Dependent on TNF Signaling and Neutrophil Trafficking Audrey Bernut,Mai Nguyen-Chi,Iman Halloum,Jean-Louis Herrmann,Georges Lutfallaet al. PLoS Pathogens, 2016, 12 (11), pp.e1005986. ⟨10.1371/journal.ppat.1005986⟩ Article dans une revue hal-02086787v1
Deciphering the complexity of macrophage biology and function with the zebrafish model Nguyen-Chi Mai,Laplace-Builhé Béryl,Jorgensen Christian,Farida Djouad Macrophage, 2016, 3, ⟨10.14800/Macrophage.1260⟩ Article dans une revue hal-02097516v1
Identification of polarized macrophage subsets in zebrafish Mai Nguyen-Chi,Béryl Laplace-Builhé,Jana Travnickova,Patricia Luz-Crawford,Gautier Tejedoret al. eLife, 2015, 4, ⟨10.7554/eLife.07288⟩ Article dans une revue hal-01834168v2
Transient infection of the zebrafish notochord with E. coli induces chronic inflammation Mai Nguyen Chi,Quang Tien Phan,Catherine Suarez Dormoy Gonzalez,Jean François Dubremetz,Jean-Pierre Levraudet al. Disease Models & Mechanisms, 2014, 7 (7), pp.871-882. ⟨10.1242/dmm.014498⟩ Article dans une revue hal-02088301v1
Morphogenesis and Cell Fate Determination within the Adaxial Cell Equivalence Group of the Zebrafish Myotome Mai Nguyen-Chi,Robert Bryson-Richardson,Carmen Sonntag,Thomas E Hall,Abigail Gibsonet al. PLoS Genetics, 2012, 8 (10), pp.e1003014. ⟨10.1371/journal.pgen.1003014⟩ Article dans une revue hal-02097514v1
The RNA-binding protein ELAVL1/HuR is essential for mouse spermatogenesis, acting both at meiotic and postmeiotic stages. Mai Nguyen Chi,Jacques Auriol,Bernard Jégou,Dimitris L. Kontoyiannis,James M. A. Turneret al. Molecular Biology of the Cell, 2011, 22 (16), pp.2875-85. ⟨10.1091/mbc.E11-03-0212⟩ Article dans une revue hal-00682606v1
Temporally regulated traffic of HuR and its associated ARE-containing mRNAs from the chromatoid body to polysomes during mouse spermatogenesis. Mai Nguyen Chi,Frédéric Chalmel,Eric Agius,Nathalie Vanzo,Khalid S. A. Khabaret al. PLoS ONE, 2009, 4 (3), pp.e4900. ⟨10.1371/journal.pone.0004900⟩ Article dans une revue inserm-00516318v1

Communication dans un congrès (2)

Pro-inflammatory macrophages mediated TNF-alpha signalling is required for caudal fin regenerationin zebrafish larvae B Laplace-Builhe,Mai Nguyen-Chi,J Travnickova,C Luz-Crawford,G. Tejedoret al. ANNALS OF THE RHEUMATIC DISEASES, Mar 2015, London, United Kingdom. pp.A16.1 - A16, ⟨10.1136/annrheumdis-2015-207259.37⟩ Communication dans un congrès hal-01834525v1
Identification of macrophage subsets in zebrafish larvae Mai Nguyen-Chi,B Laplace-Builhe,J Travnickova,C Luz-Crawford,G. Tejedoret al. ANNALS OF THE RHEUMATIC DISEASES, Mar 2015, London, United Kingdom. pp.A8.2 - A8, ⟨10.1136/annrheumdis-2015-207259.19⟩ Communication dans un congrès hal-01834463v1

Pré-publication, Document de travail (1)

Differential response of macrophages and neutrophils to trypanosome infections in zebrafish: occurrence of foamy macrophages Sem Jacobs,Éva Dóró,Ffion Hammond,Mai Nguyen-Chi,Georges Lutfallaet al. 2020 Pré-publication, Document de travail hal-02998164v1