Mariano Ostuni

Publications

Article dans une revue (59)

Pharmacological inhibition of polrmt mimicking polrmt rare variants associated with sideroblastic anemia, strongly inhibits proliferation and differentiation of human erythroblasts Ophélie Evrard,Cécile Deleschaux,Sophie Lefevre,Hakim Ouled-Haddou,Jessica Platonet al. Blood, 2025, 146 (Supplement 1), pp.4658-4658. ⟨10.1182/blood-2025-4658⟩ Article dans une revue hal-05413691v1
Alpha hemolysin of E. coli induces hemolysis of human erythrocytes independently of toxin interaction with membrane proteins Lucía Cané,Nicolás Andrés Saffioti,Sandrine Genetet,María Antonieta Daza Millone,Mariano A. Ostuniet al. Biochimie, 2024, 216, pp.3-13. ⟨10.1016/j.biochi.2023.10.008⟩ Article dans une revue hal-05538358v1
Hydrogen Peroxide Diffusion Across the Red Blood Cell Membrane Occurs Mainly by Simple Diffusion Through the Lipid Fraction Florencia Orrico,Ana Clara Lopez,Nicolas Silva,Mélanie Franco,Isabelle Mouro-Chanteloupet al. Free Radical Biology and Medicine, 2024, 226, pp.389-396. ⟨10.1016/j.freeradbiomed.2024.11.031⟩ Article dans une revue hal-05527761v1
Reframing thalassaemia syndrome as a benign haematopoietic stem cell disorder Aurelio Maggio,Mariasanta Napolitano,Ali Taher,Rayan Bou-Fakhredin,Mariano Anibal Ostuni British Journal of Haematology, 2024, 206 (2), pp.464-477. ⟨10.1111/bjh.19919⟩ Article dans une revue hal-05538301v1
Alpha hemolysin of Escherichia coli induces a necrotic-like procoagulant state in platelets Kenia Pérez Vázquez,Julia Tau,M. Florencia Leal Denis,Claudio Fader,Mariano A. Ostuniet al. Biochimie, 2024, 227, pp.1-14. ⟨10.1016/j.biochi.2024.06.001⟩ Article dans une revue hal-05524324v1
Mitochondrial retention in mature red blood cells from patients with sickle cell disease is associated with stress erythropoiesis but not with proinflammatory state Marc Romana,Sandrine Laurance,Marie‐dominique Hardy-Dessources,Laetitia Claer,Sylvie Ravionet al. HemaSphere, 2024, 8 (11), ⟨10.1002/hem3.70030⟩ Article dans une revue hal-05431607v1
Mitochondrial retention in mature red blood cells from patients with sickle cell disease is associated with stress erythropoiesis but not with proinflammatory state Marc Romana,Sandrine Laurance,Marie‐dominique Hardy-Dessources,Laetitia Claer,Sylvie Ravionet al. HemaSphere, 2024, 8 (11), ⟨10.1002/hem3.70030⟩ Article dans une revue hal-04774791v1
Oxidative Stress in Healthy and Pathological Red Blood Cells Florencia Orrico,Sandrine Laurance,Ana C Lopez,Sophie D Lefevre,Leonor Thomsonet al. Biomolecules, 2023, 13 (8), pp.1262. ⟨10.3390/biom13081262⟩ Article dans une revue hal-04964116v1
Physiology of Red Cell Lineage: From Erythroblast Progenitors to Mature Red Blood Cell Sarah Ducamp,Mariano A. Ostuni International Journal of Molecular Sciences, 2023, 24 (11), pp.9715. ⟨10.3390/ijms24119715⟩ Article dans une revue hal-05331834v1
Homeostasis of extracellular ATP in uninfected RBCs from a Plasmodium falciparum culture and derived microparticles Cora L Alvarez,Arnaud Chêne,Jean-Philippe Semblat,Benoît Gamain,Claudine Lapouméroulieet al. Biochimica et Biophysica Acta:Biomembranes, 2022, 1864, ⟨10.1016/j.bbamem.2022.183980⟩ Article dans une revue hal-05331833v1
Mechanosensitive Pannexin 1 Activity Is Modulated by Stomatin in Human Red Blood Cells Sarah Rougé,Sandrine Genetet,Maria Florencia Leal Denis,Michael Dussiot,Pablo Julio Schwarzbaumet al. International Journal of Molecular Sciences, 2022, 23 (16), pp.9401. ⟨10.3390/ijms23169401⟩ Article dans une revue hal-05331819v1
Transmission Electron Microscopy to Follow Ultrastructural Modifications of Erythroblasts Upon ex vivo Human Erythropoiesis Alice Dussouchaud,Julieta Jacob,Charles Secq,Jean-Marc Verbavatz,Martina Moraset al. Frontiers in Physiology, 2022, 12, pp.791691. ⟨10.3389/fphys.2021.791691⟩ Article dans une revue hal-05331816v1
The permeability of human red blood cell membranes to hydrogen peroxide is independent of aquaporins Florencia Orrico,Ana C Lopez,Daniela Saliwonczyk,Cecilia Acosta,Ismael Rodriguez-Greccoet al. Journal of Biological Chemistry, 2022, 298 (1), pp.101503. ⟨10.1016/j.jbc.2021.101503⟩ Article dans une revue hal-05331813v1
Interactive Dynamics of Cell Volume and Cell Death in Human Erythrocytes Exposed to α-Hemolysin from Escherichia coli Nicolas Saffioti,Natalia Lauri,Lucia Cané,Rodolfo Gonzal-Lebrero,Karina Allevaet al. International Journal of Molecular Sciences, 2022, 23 (2), pp.872. ⟨10.3390/ijms23020872⟩ Article dans une revue hal-03651508v1
Deficient mitophagy pathways in sickle cell disease Suella Martino,Jean‐benoit Arlet,Marie‐hélène Odièvre,Vincent Jullien,Martina Moraset al. British Journal of Haematology, 2021, 193 (5), pp.988-993. ⟨10.1111/bjh.17416⟩ Article dans une revue hal-05521999v1
Downregulation of Mitochondrial TSPO Inhibits Mitophagy and Reduces Enucleation During Human Terminal Erythropoiesis Martina Moras,Claude Hattab,Pedro Gonzalez-Menendez,Suella Martino,Jerome Largheroet al. International Journal of Molecular Sciences, 2020, 21 (23), pp.9066. ⟨10.3390/ijms21239066⟩ Article dans une revue hal-03384776v1
Versatile Dimerisation Process of Translocator Protein (TSPO) Revealed by an Extensive Sampling Based on a Coarse-Grained Dynamics Study Rajas Rao,Julien Diharce,Bérénice Dugué,Mariano A. Ostuni,Frédéric Cadetet al. Journal of Chemical Information and Modeling, 2020, 60 (8), pp.3944-3957. ⟨10.1021/acs.jcim.0c00246⟩ Article dans une revue hal-05521989v1
CX3CL1 homo-oligomerization drives cell-to-cell adherence Mariano A. Ostuni,Patricia Hermand,Emeline Saindoy,Noëlline Guillou,Julie Guellecet al. Scientific Reports, 2020, 10 (1), pp.9069. ⟨10.1038/s41598-020-65988-w⟩ Article dans une revue inserm-02877584v1
Human erythroid differentiation requires VDAC1-mediated mitochondrial clearance Martina Moras,Claude Hattab,Pedro Gonzalez-Menendez,Claudio Fader,Michael Dussiotet al. Haematologica, 2020, ⟨10.3324/haematol.2020.257121⟩ Article dans une revue halshs-03429293v1
TSPO2 translocates 5‐aminolevulinic acid into human erythroleukemia cells Hana Manceau,Sophie Lefevre,Arienne Mirmiran,Claude Hattab,Hugo Sugieret al. Biology of the Cell, 2020, 112 (4), pp.113-126. ⟨10.1111/boc.201900098⟩ Article dans une revue hal-05521980v1
An Overview of Different Strategies to Recreate the Physiological Environment in Experimental Erythropoiesis Cécile Deleschaux,Martina Moras,Sophie D Lefevre,Mariano A. Ostuni International Journal of Molecular Sciences, 2020, 21 (15), pp.5263. ⟨10.3390/ijms21155263⟩ Article dans une revue hal-05331772v1
TSPO2 translocates 5‐aminolevulinic acid into human erythroleukemia cells Hana Manceau,Sophie Lefevre,Arienne Mirmiran,Claude Hattab,Hugo R Sugieret al. Biology of the Cell, In press, ⟨10.1111/boc.201900098⟩ Article dans une revue hal-02490892v1
Salivary extracellular vesicles can modulate purinergic signalling in oral tissues by combined ectonucleoside triphosphate diphosphohydrolases and ecto-5′-nucleotidase activities Debora A. Gonzalez,Matias M Barbieri van Haaster,Emmanuel Quinteros Villarruel,Claude Hattab,Mariano Aníbal Ostuniet al. Molecular and Cellular Biochemistry, 2019, 463 (1-2), pp.1-11. ⟨10.1007/s11010-019-03624-6⟩ Article dans une revue hal-05363757v1
ATPe Dynamics in Protozoan Parasites. Adapt or Perish Natalia Lauri,Zaher Bazzi,Cora L Alvarez,María F Leal Denis,Julieta Schachteret al. Genes, 2018, 10 (1), pp.16. ⟨10.3390/genes10010016⟩ Article dans une revue hal-05431606v1
Induction of ATP Release, PPIX Transport, and Cholesterol Uptake by Human Red Blood Cells Using a New Family of TSPO Ligands Irene Marginedas-Freixa,Cora L Alvarez,Martina Moras,Claude Hattab,Guillaume Bouyeret al. International Journal of Molecular Sciences, 2018, 19 (10), pp.3098. ⟨10.3390/ijms19103098⟩ Article dans une revue hal-01926983v1
Dynamic regulation of extracellular ATP in Escherichia coli Cora Lilia Alvarez,Gerardo Corradi,Natalia Lauri,Irene Marginedas-Freixa,María Florencia Leal Deniset al. Biochemical Journal, 2017, 474 (8), pp.1395-1416. ⟨10.1042/BCJ20160879⟩ Article dans une revue hal-05524348v1
From Erythroblasts to Mature Red Blood Cells: Organelle Clearance in Mammals Martina Moras,Sophie D Lefevre,Mariano A. Ostuni Frontiers in Physiology, 2017, 8, pp.1076. ⟨10.3389/fphys.2017.01076⟩ Article dans une revue hal-05331766v1
TSPO ligands stimulate ZnPPIX transport and ROS accumulation leading to the inhibition of P. falciparum growth in human blood I Marginedas-Freixa,C Hattab,G Bouyer,F Halle,A Cheneet al. Scientific Reports, 2016, 6, ⟨10.1038/srep33516⟩ Article dans une revue hal-05431604v1
TSPO ligands stimulate ZnPPIX transport and ROS accumulation leading to the inhibition of P. falciparum growth in human blood I Marginedas-Freixa,C Hattab,G Bouyer,F Halle,A Cheneet al. Scientific Reports, 2016, 6, pp.33516 ⟨10.1038/srep33516⟩ Article dans une revue hal-01369499v1
Construction and validation of an atomic model for bacterial TSPO from electron microscopy density, evolutionary constraints, and biochemical and biophysical data Konrad Hinsen,Aurore Vaitinadapoule,Mariano A. Ostuni,Catherine Etchebest,Jean-Jacques Lacapere Biochimica et Biophysica Acta:Biomembranes, 2015, 1848 (2), pp.568-580. ⟨10.1016/j.bbamem.2014.10.028⟩ Article dans une revue istex hal-05431600v1
Rat submandibular glands secrete nanovesicles with NTPDase and 5′-nucleotidase activities Débora A González,Patricia Egido,Noelia B Balcarcel,Claude Hattab,Martín M Barbieri van Haasteret al. Purinergic Signalling, 2015, 11 (1), pp.107-116. ⟨10.1007/s11302-014-9437-0⟩ Article dans une revue hal-05363754v1
Construction and validation of an atomic model for bacterial TSPO from electron microscopy density, evolutionary constraints, and biochemical and biophysical data. Konrad Hinsen,Aurore Vaitinadapoule,Mariano A. Ostuni,Catherine Etchebest,Jean-Jacques Lacapere Biochimica et Biophysica Acta:Biomembranes, 2015, 1848 (2), pp.568-580. ⟨10.1016/j.bbamem.2014.10.028⟩ Article dans une revue istex hal-01171268v1
Translocator Protein-Mediated Stabilization of Mitochondrial Architecture during Inflammation Stress in Colonic Cells. Leeyah Issop,Mariano A Ostuni,Sunghoon Lee,Mireille Laforge,Gabriel Péranziet al. PLoS ONE, 2015, 11 (4), pp.e0152919. ⟨10.1371/journal.pone.0152919⟩ Article dans une revue hal-01302159v1
CX3CL1, a chemokine finely tuned to adhesion: critical roles of the stalk glycosylation and the membrane domain Mariano A. Ostuni,Julie Guellec,Patricia Hermand,Pauline Durand,Christophe Combadièreet al. Biology Open, 2014, 3 (12), pp.1173-1182. ⟨10.1242/bio.20149845⟩ Article dans une revue hal-05431601v1
CX3CL1, a chemokine finely tuned to adhesion: critical roles of the stalk glycosylation and the membrane domain Mariano A. Ostuni,Julie Guellec,Patricia Hermand,Pauline Durand,Christophe Combadièreet al. Biology Open, 2014, 3, pp.1173-1182. ⟨10.1242/bio.20149845⟩ Article dans une revue inserm-01095507v1
Thyrotropin receptor antibodies in parotid saliva O. Tumilasci,M. Arqueros,Mariano A. Ostuni,E. El Tamer,Alberto Houssay Journal of Endocrinological Investigation, 2014, 19 (7), pp.412-414. ⟨10.1007/BF03349884⟩ Article dans une revue hal-05456436v1
Effect of translocator protein (18 kDa)‐ligand binding on neurotransmitter‐induced salivary secretion in rat submandibular glands Mariano A. Ostuni,Omar Tumilasci,Gabriel Péranzi,Estela Cardoso,Liliana Contreraset al. Biology of the Cell, 2012, 100 (7), pp.427-439. ⟨10.1042/BC20070157⟩ Article dans une revue hal-05452265v1
Translocator protein (18 kDa) ligand PK 11195 induces transient mitochondrial Ca 2+ release leading to transepithelial Cl − secretion in HT‐29 human colon cancer cells Mariano A. Ostuni,Robert Ducroc,Gabriel Péranzi,Marie‐christine Tonon,Vassilios Papadopouloset al. Biology of the Cell, 2012, 99 (11), pp.639-647. ⟨10.1042/BC20070048⟩ Article dans une revue istex hal-05452253v1
trans Arachidonic acid isomers inhibit NADPH-oxidase activity by direct interaction with enzyme components H. Souabni,V. Thoma,Tania Bizouarn,C. Chatgilialoglu,A. Siafaka-Kapadaiet al. Biochimica et Biophysica Acta:Biomembranes, 2012, 1818 (9), pp.2314-2324. ⟨10.1016/j.bbamem.2012.04.018⟩ Article dans une revue hal-05331761v1
Distribution, pharmacological characterization and function of the 18 kDa translocator protein in rat small intestine Mariano Anibal Ostuni,Gabriel Péranzi,Robert Ducroc,Magali Fasseu,Branislav Vidicet al. Biology of the Cell, 2012, 101 (10), pp.573-586. ⟨10.1042/BC20080231⟩ Article dans une revue hal-05452296v1
Combinatorial Discovery of Fluorescent Pharmacophores by Multicomponent Reactions in Droplet Arrays Olga Burchak,Laurent Mugherli,Mariano A. Ostuni,Jean Jacques Lacapère,Maxim Balakirev Journal of the American Chemical Society, 2011, 133 (26), pp.10058-10061. ⟨10.1021/ja204016e⟩ Article dans une revue hal-05521965v1
Expression of functional mammal flavocytochrome b558 in yeast: Comparison with improved insect cell system Mariano A. Ostuni,Leila B Lamanuzzi,Tania Bizouarn,Marie-Claire Dagher,Laura Baciou Biochimica et Biophysica Acta:Biomembranes, 2010, 1798 (6), pp.1179-1188. ⟨10.1016/j.bbamem.2010.02.016⟩ Article dans une revue hal-05431596v1
Expression of functional mammal flavocytochrome b558 in yeast: Comparison with improved insect cell system Mariano A. Ostuni,Leila Lamanuzzi,Tania Bizouarn,Marie-Claire Dagher,Laura Baciou Biochimica et Biophysica Acta:Biomembranes, 2010, 1798 (6), pp.1179-1188. ⟨10.1016/j.bbamem.2010.02.016⟩ Article dans une revue hal-05452317v1
TRO40303, a New Cardioprotective Compound, Inhibits Mitochondrial Permeability Transition Sophie Schaller,Stéphanie Paradis,Gladys A Ngoh,Rana Assaly,Bruno Buissonet al. Journal of Pharmacology and Experimental Therapeutics, 2010, 333 (3), pp.696-706. ⟨10.1124/jpet.110.167486⟩ Article dans une revue hal-05431598v1
TRO40303, a new cardioprotective compound, inhibits mitochondrial permeability transition. Sophie Schaller,Stéphanie Paradis,Gladys A. Ngoh,Rana Assaly,Bruno Buissonet al. Journal of Pharmacology and Experimental Therapeutics, 2010, 333 (3), pp.696-706. ⟨10.1124/jpet.110.167486⟩ Article dans une revue inserm-00497589v1
Overexpression of translocator protein in inflammatory bowel disease: Potential diagnostic and treatment value Mariano A. Ostuni,Leeyah Issop,Gabriel Péranzi,Francine Walker,Magali Fasseuet al. Inflammatory Bowel Diseases, 2010, 16 (9), pp.1476-1487. ⟨10.1002/ibd.21250⟩ Article dans une revue hal-05431599v1
Expression of functional mammal flavocytochrome b(558) in yeast: comparison with improved insect cell system. Mariano A. Ostuni,Leila B. Lamanuzzi,Tania Bizouarn,Marie-Claire Dagher,Laura Baciou BBA - Biochimica et Biophysica Acta, 2010, 1798 (6), pp.1179-88. ⟨10.1016/j.bbamem.2010.02.016⟩ Article dans une revue hal-00820712v1
Modulation of the activity of the NADPH oxidase system by reactive oxygen species: influence of catalase Mariano A. Ostuni,T. Bizouarn,L. Baciou,C. Houee-Levin Radiation Protection Dosimetry, 2010, 143 (2-4), pp.166-171. ⟨10.1093/rpd/ncq518⟩ Article dans une revue hal-05521957v1
Translocator protein (18 kDa) is involved in primitive erythropoiesis in zebrafish Christine Rampon,Mohamed Rouzaffour,Mariano A. Ostuni,Pascale Dufourcq,Christelle Girardet al. FASEB Journal, 2009, 23 (12), pp.4181-4192. ⟨10.1096/fj.09-129262⟩ Article dans une revue hal-05452304v1
Discovery of a functional immunoreceptor tyrosinebased switch motif in a 7-transmembrane-spanning receptor: role in the orexin receptor OX1R-driven apoptosis Aadil El Firar,Thierry Voisin,Christiane Rouyer-Fessard,Mariano A. Ostuni,Alain Couvineauet al. FASEB Journal, 2009, 23 (12), pp.4069-4080. ⟨10.1096/fj.09-131367⟩ Article dans une revue hal-05452300v1
Characterization of a functional NTPDase in the endoplasmic reticulum of rat submandibular salivary gland Mariano A. Ostuni,P Egido,G Peranzi,Gl Alonso,J-J Lacapereet al. Physiological Research, 2009, 58 (6), pp.843-854. ⟨10.33549/physiolres.931682⟩ Article dans une revue hal-05324635v1
Secondary and tertiary structures of the transmembrane domains of the translocator protein TSPO determined by NMR. Stabilization of the TSPO tertiary fold upon ligand binding Samuel Murail,Jean-Claude Robert,Yves-Marie Coïc,Jean-Michel Neumann,Mariano A Ostuniet al. Biochimica et Biophysica Acta:Biomembranes, 2008, 1778 (6), pp.1375-1381. ⟨10.1016/j.bbamem.2008.03.012⟩ Article dans une revue hal-05440360v1
Identification and Characterization of Cholest-4-en-3-one, Oxime (TRO19622), a Novel Drug Candidate for Amyotrophic Lateral Sclerosis Thierry Bordet,Bruno Buisson,Magali Michaud,Cyrille Drouot,Pascale Galéaet al. Journal of Pharmacology and Experimental Therapeutics, 2007, 322 (2), pp.709-720. ⟨10.1124/jpet.107.123000⟩ Article dans une revue hal-05452248v1
STANDARDIZATION OF A SIMPLE METHOD TO STUDY WHOLE SALIVA: CLINICAL USE IN DIFFERENT PATHOLOGIES Omar René Tumilasci,Estela M. L. Cardoso,Liliana N. Contreras,Juan Belforte,Alejandro L. Arreggeret al. Acta odontologica latinoamericana : AOL, 2006, 19 (2), pp.47-51 Article dans une revue hal-05324342v1
Stoichiometry of ATP and metal cofactor interaction with the sarcoplasmic reticulum Ca2+–ATPase: A binding model accounting for radioisotopic and fluorescence results Débora A González,Mariano A. Ostuni,Jean-Jacques Lacapère,Guillermo L Alonso Biophysical Chemistry, 2006, 124 (1), pp.27-34. ⟨10.1016/j.bpc.2006.05.025⟩ Article dans une revue hal-05324364v1
Un nouveau rôle pour le récepteur périphérique des benzodiazépines ? Mariano A. Ostuni,Jean-Jacques Lacapère Médecine/Sciences, 2005, 21 (3), pp.240-242. ⟨10.1051/medsci/2005213240⟩ Article dans une revue hal-05431593v1
Characterization of the cholesterol recognition amino acid consensus sequence of the peripheral-type benzodiazepine receptor Nadège Jamin,Jean-Michel Neumann,Mariano A. Ostuni,Thi Kim Ngoc Vu,Zhi-Xing Yaoet al. Molecular Endocrinology, 2005, 19 (3), pp.588-594. ⟨10.1210/me.2004-0308⟩ Article dans une revue hal-05324303v1
Functional characterization and expression of PBR in rat gastric mucosa: stimulation of chloride secretion by PBR ligands Mariano A. Ostuni,K. Marazova,G. Peranzi,B. Vidic,V. Papadopouloset al. AJP - Gastrointestinal and Liver Physiology, 2004, 286 (6), pp.G1069-G1080. ⟨10.1152/ajpgi.00290.2003⟩ Article dans une revue hal-05431591v1
Calcium additional to that bound to the transport sites is required for full activation of the sarcoplasmic reticulum Ca-ATPase from skeletal muscle Guillermo Alonso,Débora González,Delia Takara,Mariano A. Ostuni,Gabriel Sánchez Biochimica et Biophysica Acta - Molecular Cell Research, 1998, 1405 (1-3), pp.47-54. ⟨10.1016/s0167-4889(98)00101-3⟩ Article dans une revue istex hal-05431589v1

Chapitre d'ouvrage (3)

Mitophagy in erythropoiesis Julieta Jacob,Pablo Reta,Mariano A. Ostuni,María Colombo,Claudio Fader Mitophagy in Health and Disease, Elsevier, pp.169-185, 2025, ⟨10.1016/B978-0-443-15260-3.00008-9⟩ Chapitre d'ouvrage hal-05452333v1
Recombinant Overexpression of Mammalian TSPO Isoforms 1 and 2 Lucile Senicourt,Soria Iatmanen-Harbi,Claude Hattab,Mariano Anibal Ostuni,Marie-France Giraudet al. Membrane Protein Structure and Function Characterization, 1635, Springer New York, pp.1-25, 2017, Methods in Molecular Biology, ⟨10.1007/978-1-4939-7151-0_1⟩ Chapitre d'ouvrage hal-05452323v1
Characterization of Membrane Protein Preparations: Measurement of Detergent Content and Ligand Binding After Proteoliposomes Reconstitution Mariano A. Ostuni,Soria Iatmanen,David Teboul,Jean-Claude Robert,Jean-Jacques Lacapère Membrane Protein Structure Determination, 654, Humana Press, pp.3-18, 2010, Methods in Molecular Biology, ⟨10.1007/978-1-60761-762-4_1⟩ Chapitre d'ouvrage hal-05452328v1