Marie-Christine Chaboissier

Publications

Article dans une revue (42)

Gonadal sex determination in vertebrates: rethinking established mechanisms Dagmar Wilhelm,Aitana Perea-Gomez,Axel Newton,Marie-Christine Chaboissier Development (Cambridge, England), 2025, 152 (6), pp.dev204592. ⟨10.1242/dev.204592⟩ Article dans une revue (article de synthèse) hal-05166957v1
NR2F2 is required in the embryonic testis for fetal Leydig cell development Aitana Perea-Gomez,Natividad Bellido Carreras,Magali Dhellemmes,Furong Tang,Coralie Le Galloet al. eLife, 2025, 14, ⟨10.7554/elife.103783⟩ Article dans une revue hal-05164909v1
The −KTS splice variant of WT1 is essential for ovarian determination in mice Elodie Gregoire,Marie-Cécile de Cian,Roberta Migale,Aitana Perea-Gomez,Sébastien Schaubet al. Science, 2023, 382 (6670), pp.600-606. ⟨10.1126/science.add8831⟩ Article dans une revue hal-04285584v1
Crosstalk between androgen receptor and WNT/β-catenin signaling causes sex-specific adrenocortical hyperplasia in mice Rodanthi Lyraki,Anaëlle Grabek,Amélie Tison,Lahiru Chamara Weerasinghe Arachchige,Mirko Peitzschet al. Disease Models & Mechanisms, 2023, 16 (6), pp.dmm050053. ⟨10.1242/dmm.050053⟩ Article dans une revue hal-04217913v1
Gadd45g is required for timely Sry expression independently of RSPO1 activity Nick Warr,Pam Siggers,Joel May,Nicolas Chalon,Madeleine Popeet al. Reproduction [Cambridge], 2022, 163, pp.333-340. ⟨10.1530/REP-21-0443⟩ Article dans une revue hal-03650971v1
Origin, specification and differentiation of a rare supporting-like lineage in the developing mouse gonad Chloé Mayère,Violaine Regard,Aitana Perea-Gomez,Corey Bunce,Yasmine Neirijncket al. Science Advances , 2022, 8 (21), ⟨10.1126/sciadv.abm0972⟩ Article dans une revue hal-03684448v1
Single‐cell transcriptomics reveal temporal dynamics of critical regulators of germ cell fate during mouse sex determination Anne Amandine Chassot,Chloé Mayère,Yasmine Neirijnck,Pauline Sararols,Chris Randset al. FASEB Journal, 2021, 35 (4), ⟨10.1096/fj.202002420R⟩ Article dans une revue hal-03432083v1
Arrest of WNT/β-catenin signaling enables the transition from pluripotent to differentiated germ cells in mouse ovaries Morgane Le Rolle,Filippo Massa,Pam Siggers,Laurent Turchi,Agnès Loubatet al. Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (30), pp.e2023376118. ⟨10.1073/pnas.2023376118⟩ Article dans une revue hal-03432069v1
Arrest of WNT/β-catenin signaling enables the transition from pluripotent to differentiated germ cells in mouse ovaries Morgane Le Rolle,Pam Siggers,Laurent Turchi,Agnès Loubat,Bon-Kyoung Kooet al. Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (30), pp.e2023376118. ⟨10.1073/pnas.2023376118⟩ Article dans une revue hal-04764961v1
Single‐cell transcriptomics reveal temporal dynamics of critical regulators of germ cell fate during mouse sex determination Chloé Mayère,Yasmine Neirijnck,Pauline Sararols,Chris Rands,Isabelle Stévantet al. FASEB Journal, 2021, 35 (4), ⟨10.1096/fj.202002420R⟩ Article dans une revue hal-03215407v1
Arrest of WNT/β-catenin signaling enables the transition from pluripotent to differentiated germ cells in mouse ovaries Morgane Le Rolle,Filippo Massa,Pam Siggers,Laurent Turchi,Agnès Loubatet al. Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (30), pp.e2023376118. ⟨10.1073/pnas.2023376118⟩ Article dans une revue hal-03357217v1
Sox8 and Sox9 act redundantly for ovarian-to-testicular fate reprogramming in the absence of R-spondin1 in mouse sex reversals Nainoa Richardson,Isabelle Gillot,Elodie P Gregoire,Sameh A Youssef,Dirk de Rooijet al. eLife, 2020, 9, ⟨10.7554/elife.53972⟩ Article dans une revue hal-02992419v1
Mouse Gonad Development in the Absence of the Pro-Ovary Factor WNT4 and the Pro-Testis Factor SOX9 Furong Tang,Nainoa Richardson,Audrey Albina,Marie-Christine Chaboissier,Aitana Perea-Gomez Cells, 2020, 9 (5), pp.1103. ⟨10.3390/cells9051103⟩ Article dans une revue hal-02890945v1
R-spondin2 signaling is required for oocyte-driven intercellular communication and follicular growth Marie-Cécile de Cian,Elodie P Gregoire,Morgane Le Rolle,Simon Lachambre,Magali Mondinet al. Cell Death and Differentiation, 2020, 27 (10), pp.2856 - 2871. ⟨10.1038/s41418-020-0547-7⟩ Article dans une revue hal-02992481v1
R-spondin signalling is essential for the maintenance and differentiation of mouse nephron progenitors Valerie Pi Vidal,Fariba Jian-Motamedi,Samah Rekima,Elodie P Gregoire,Emmanuelle Szenker-Raviet al. eLife, 2020, 9, ⟨10.7554/elife.53895⟩ Article dans une revue hal-02992461v1
Retinoic acid synthesis by ALDH1A proteins is dispensable for meiosis initiation in the mouse fetal ovary Anne-Amandine Chassot,Morgane Le Rolle,Geneviève Jolivet,Isabelle Stevant,Jean-Marie Guigoniset al. Science Advances , 2020, 6, p. eaaz1261. ⟨10.1126/sciadv.aaz1261⟩ Article dans une revue hal-03028656v1
The Adult Adrenal Cortex Undergoes Rapid Tissue Renewal in a Sex-Specific Manner Anaëlle Grabek,Bastien Dolfi,Bryan Klein,Fariba Jian-Motamedi,Marie-Christine Chaboissieret al. Cell Stem Cell, 2019, ⟨10.1016/j.stem.2019.04.012⟩ Article dans une revue hal-02167820v1
Dissecting Cell Lineage Specification and Sex Fate Determination in Gonadal Somatic Cells Using Single-Cell Transcriptomics Isabelle Stévant,Françoise Kühne,Andy Greenfield,Marie-Christine Chaboissier,Emmanouil Dermitzakiset al. Cell Reports, 2019, 26 (12), pp.3272-3283.e3. ⟨10.1016/j.celrep.2019.02.069⟩ Article dans une revue hal-02189264v1
NRG1 signalling regulates the establishment of Sertoli cell stock in the mouse testis Anne Amandine Chassot,Elodie Gregoire,Isabelle Stevant,Anne-Amandine Chassot,Luc Martinet al. Molecular and Cellular Endocrinology, 2018, 478, pp.17-31. ⟨10.1016/j.mce.2018.07.004⟩ Article dans une revue hal-03432089v1
NRG1 signalling regulates the establishment of Sertoli cell stock in the mouse testis Elodie P Gregoire,Isabelle Stevant,Anne-Amandine Chassot,Luc Martin,Simon Lachambreet al. Molecular and Cellular Endocrinology, 2018, 478, pp.17 - 31. ⟨10.1016/j.mce.2018.07.004⟩ Article dans une revue hal-03549197v1
Constitutive WNT/CTNNB1 activation triggers spermatogonial stem cell proliferation and germ cell depletion Anne Amandine Chassot,Morgane Le Rolle,Maxime Jourden,Maketo Taketo,Norbert Ghyselincket al. Developmental Biology, 2017, 426 (1), pp.17-27. ⟨10.1016/j.ydbio.2017.04.010⟩ Article dans une revue hal-03432091v1
Retinoic acid signaling is dispensable for somatic development and function in the mammalian ovary Anna Minkina,Robin Lindeman,Micah Gearhart,Anne Amandine Chassot,Marie-Christine Chaboissieret al. Developmental Biology, 2017, 424 (2), pp.208-220. ⟨10.1016/j.ydbio.2017.02.015⟩ Article dans une revue hal-03432092v1
R-spondin1 Controls Muscle Cell Fusion through Dual Regulation of Antagonistic Wnt Signaling Pathways Floriane Lacour,Elsa Vezin,C. Florian Bentzinger,Marie-Claude Sincennes,Lorenzo Giordaniet al. Cell Reports, 2017, 18 (10), pp.2320-2330. ⟨10.1016/j.celrep.2017.02.036⟩ Article dans une revue hal-02486025v1
Involvement of &lt;em&gt;FOXL2&lt;/em&gt; and &lt;em&gt;RSPO1&lt;/em&gt; in ovarian determination, development, and maintenance in mammals Maëlle Pannetier,Anne-Amandine Chassot,Marie-Christine Chaboissier,Eric Pailhoux Sexual Development, 2016, 10 (4), pp.167-184. ⟨10.1159/000448667⟩ Article dans une revue (article de synthèse) hal-02638713v1
Steroidogenic organ development and homeostasis: A WT1-centric view. Roberto Bandiera,Sonia Sacco,Valerie P I Vidal,Marie-Christine Chaboissier,Andreas Schedl Molecular and Cellular Endocrinology, 2015, 408, pp.145-55 Article dans une revue hal-01255277v1
Ovarian development and disease: The known and the unexpected. Anna Biason-Lauber,Marie-Christine Chaboissier Seminars in Cell and Developmental Biology, 2015, 45 (1), pp.59-67 Article dans une revue hal-01255240v1
R-spondin1, WNT4, and the CTNNB1 signaling pathway: strict control over ovarian differentiation. Anne-Amandine Chassot,Isabelle Gillot,Marie-Christine Chaboissier Reproduction [Cambridge], 2014, 148 (6), pp.R97-110. ⟨10.1530/REP-14-0177⟩ Article dans une revue hal-01421167v1
R-spondin1 deficiency enhances β-Cell neogenesis in a murine model of diabetes. Jasleen K Chahal,Victor S C Wong,Marie-Christine Chaboissier,Patricia L Brubaker Pancreas, 2014, 43 (1), pp.93-102. ⟨10.1097/MPA.0b013e3182a70bfb⟩ Article dans une revue hal-00968722v1
Marker genes identify three somatic cell types in the fetal mouse ovary. Raphael H Rastetter,Pascal Bernard,James S Palmer,Anne-Amandine Chassot,Huijun Chenet al. Developmental Biology, 2014, 394 (2), pp.242-52 Article dans une revue hal-01117482v1
Disruption of mitotic arrest precedes precocious differentiation and transdifferentiation of pregranulosa cells in the perinatal Wnt4 mutant ovary. Danielle M Maatouk,Lindsey Mork,Anne-Amandine Chassot,Marie-Christine Chaboissier,Blanche Capel Developmental Biology, 2013, epub ahead of print. ⟨10.1016/j.ydbio.2013.08.026⟩ Article dans une revue hal-00868878v1
Testicular Differentiation Occurs in Absence of R-spondin1 and Sox9 in Mouse Sex Reversals Rowena Lavery,Anne‐amandine Chassot,Eva Pauper,Elodie Gregoire,Muriel Klopfensteinet al. PLoS Genetics, 2012, 8 (12), pp.e1003170. ⟨10.1371/journal.pgen.1003170⟩ Article dans une revue hal-04765997v1
WNT4 and RSPO1 together are required for cell proliferation in the early mouse gonad. Anne-Amandine Chassot,Stephen T Bradford,Aurélie Auguste,Elodie P Gregoire,Eric Pailhouxet al. Development (Cambridge, England), 2012, 139 (23), pp.4461-72. ⟨10.1242/dev.078972⟩ Article dans une revue hal-00760283v1
XY Sox9 embryonic loss-of-function mouse mutants show complete sex reversal and produce partially fertile XY oocytes. Rowena Lavery,Aurélie Lardenois,Fariba Ranc-Jianmotamedi,Eva Pauper,Elodie P. Gregoireet al. Developmental Biology, 2011, 354 (1), pp.111-22. ⟨10.1016/j.ydbio.2011.03.029⟩ Article dans une revue istex hal-00682834v1
RSPO1/β-Catenin Signaling Pathway Regulates Oogonia Differentiation and Entry into Meiosis in the Mouse Fetal Ovary Anne-Amandine Chassot,Elodie P Gregoire,Rowena Lavery,Makoto M Taketo,Dirk G de Rooijet al. PLoS ONE, 2011, 6 (10), pp.e25641. ⟨10.1371/journal.pone.0025641⟩ Article dans une revue hal-03746225v1
Goat RSPO1 over-expression rescues sex-reversal in Rspo1-knockout XX mice but does not perturb testis differentiation in XY or sex-reversed XX mice Laurine Buscara,Fatemeh Montazer-Torbati,Sead Chadi,Aurelie A. Auguste,Johann J. Laubieret al. Transgenic Research, 2009, 18 (4), pp.649-654. ⟨10.1007/s11248-009-9247-2⟩ Article dans une revue istex hal-02662033v1
The Cerebellin 4 Precursor Gene Is a Direct Target of SRY and SOX9 in Mice Stephen T Bradford,Ryuji Hiramatsu,Madhavi P Maddugoda,Pascal Bernard,Marie-Christine Chaboissieret al. Biology of Reproduction, 2009, 80 (6), pp.1178 - 1188. ⟨10.1095/biolreprod.108.071480⟩ Article dans une revue hal-03746240v1
R-spondin1 is required for normal epithelial morphogenesis during mammary gland development Sead Chadi,Laurine Buscara,Isabelle Pechoux,Jose Costa,Johann Laubieret al. Biochemical and Biophysical Research Communications, 2009, 390 (3), pp.1040-1043. ⟨10.1016/j.bbrc.2009.10.104⟩ Article dans une revue hal-01193559v1
Activation of -catenin signaling by Rspo1 controls differentiation of the mammalian ovary Anne‐amandine Chassot,Fariba Ranc,Elodie P Gregoire,Hermien L Roepers-Gajadien,Makoto Mark Taketoet al. Human Molecular Genetics, 2008, 17 (9), pp.1264 - 1277. ⟨10.1093/hmg/ddn016⟩ Article dans une revue hal-04765969v1
Fgf9 and Wnt4 act as antagonistic signals to regulate mammalian sex determination. Yuna Kim,Akio Kobayashi,Ryohei Sekido,Leo Dinapoli,Jennifer Brennanet al. PLoS Biology, 2006, 4 (6), pp.e187. ⟨10.1371/journal.pbio.0040187⟩ Article dans une revue inserm-00708293v1
Functional analysis of &lt;i&gt;Sox8&lt;/i&gt; and &lt;i&gt;Sox9&lt;/i&gt; during sex determination in the mouse Marie-Christine Chaboissier,Akio Kobayashi,Valerie I P Vidal,Susanne Lützkendorf,Henk J G van de Kantet al. Development (Cambridge, England), 2004, 131 (9), pp.1891 - 1901. ⟨10.1242/dev.01087⟩ Article dans une revue hal-03746276v1
The Sox9 transcription factor determines glial fate choice in the developing spinal cord C. Claus Stolt,Petra Lommes,Elisabeth Sock,Marie-Christine Chaboissier,Andreas Schedlet al. Genes and Development, 2003, 17 (13), pp.1677-1689. ⟨10.1101/gad.259003⟩ Article dans une revue hal-03746292v1
The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6 Haruhiko Akiyama,Marie-Christine Chaboissier,James F Martin,Andreas Schedl,Benoit de Crombrugghe Genes and Development, 2002, 16 (21), pp.2813-2828. ⟨10.1101/gad.1017802⟩ Article dans une revue hal-03746310v1

Pré-publication, Document de travail (1)

NR2F2 is required in the embryonic testis for Fetal Leydig Cell development Aitana Perea-Gomez,Natividad Bellido-Carreras,Magali Dhellemmes,Furong Tang,Coralie Le Galloet al. 2024 Pré-publication, Document de travail hal-04735872v1

Communication dans un congrès (6)

GENIDOV: Gene network involved in ovarian development in goat and mouse Eric Pailhoux,Maëlle Pannetier,Dominique Thepot Thépot,Geneviève Jolivet,Ikrame Naciriet al. 9. Colloque Agenae / ANR, Colloque Génomique Animale et Microbienne, AGENAE - Analyse du Génome des Animaux d'Elevage (AGENAE). FRA., Mar 2012, La Rochelle, France. 1 p Communication dans un congrès hal-01193796v1
TEGOD: Transgenic studies of early acting genes in ovarian development in mouse and goats (2007-2009) Eric Pailhoux,Edmond Cribiu,Marie-Christine Chaboissier 8. Journées AGENAE, Nov 2010, Bordeaux, France Communication dans un congrès hal-01193662v1
TEGOD : Transgenic studies of Early acting Genes in Ovarian Development in mouse and goats. Eric Pailhoux,Edmond Cribiu,Marie-Christine Chaboissier 7. Colloque Agenae-Genanimal, Oct 2009, Tours, France. n.p Communication dans un congrès hal-01193526v1
R-spondin1 and Foxl2 double invalidation in mice: toward an understanding of the molecular interactions between two major ovarian differentiating pathways Aurelie A. Auguste,Anne-Amandine Chassot,Elodie Grégoire,Maëlle Pannetier,Mathias Treieret al. 5. International Symposium on the Biology of Vertebreate Sex Determination, Apr 2009, Kona, United States. n.p Communication dans un congrès hal-02815525v1
Invalidation de Foxl2 et R-spondin1 chez la souris: étude de deux voies de différenciation ovarienne Aurelie A. Auguste,Anne-Amandine Chassot,Elodie Grégoire,Maëlle Pannetier,Mathias Treieret al. 3. Journées d’Animation Scientifique du Département de Physiologie Animale et Systèmes d’Elevage, Oct 2009, Tours, France Communication dans un congrès hal-02758059v1
R-spondin1 is required to normal epithelial morphogenesis during mammary gland development Sead Chadi,Laurine Buscara,Christine Péchoux,Jose Costa,Johann Laubieret al. Mammary Gland Biology Gordon Conference, Jun 2009, Salve Regina, United States Communication dans un congrès hal-01193690v1