Marie-Clotilde ALVES-GUERRA

Publications

Pré-publication, Document de travail (2)

An in vivo CRISPR screen unveils top target genes to improve CAR-T cell efficacy in a solid tumor model Mattia Fumagalli,Dongjie An,Luca Simula,Camille Combe,Lisa Aziezet al. 2025 Pré-publication, Document de travail hal-05361481v1
Mitochondrial Aurora kinase A induces mitophagy by interacting with MAP1LC3 and Prohibitin 2 Giulia Bertolin,Marie-Clotilde Alves-Guerra,Angélique Chéron,Agnes Burel,Claude Prigentet al. 2021 Pré-publication, Document de travail hal-02566766v1

Article dans une revue (33)

Mitochondrial metabolism sustains CD8+ T cell migration for an efficient infiltration into solid tumors Luca Simula,Mattia Fumagalli,Lene Vimeux,Irena Rajnpreht,Philippe Icardet al. Nature Communications, 2024, 15, pp.2203. ⟨10.1038/s41467-024-46377-7⟩ Article dans une revue hal-04598718v1
Iron Boosts Antitumor Type 1 T-cell Responses and Anti-PD1 Immunotherapy Sarah Porte,Alexandra Audemard-Verger,Christian Wu,Aurélie Durand,Théo Levelet al. Cancer Immunology Research, 2024, 12 (9), pp.1252-1267. ⟨10.1158/2326-6066.CIR-23-0739⟩ Article dans une revue hal-04736166v1
The transcription factor ChREBP Orchestrates liver carcinogenesis by coordinating the PI3K/AKT signaling and cancer metabolism Emmanuel Benichou,Bolaji Seffou,Selin Topçu,Ophélie Renoult,Véronique Lenoiret al. Nature Communications, 2024, Nature Communications, 15 (1), pp.1879. ⟨10.1038/s41467-024-45548-w⟩ Article dans une revue hal-04696163v1
UCP2 as a Cancer Target through Energy Metabolism and Oxidative Stress Control Angèle Luby,Marie-Clotilde Alves-Guerra International Journal of Molecular Sciences, 2022, 23 (23), pp.15077. ⟨10.3390/ijms232315077⟩ Article dans une revue hal-03886848v1
UCP2 silencing restrains leukemia cell proliferation through glutamine metabolic remodeling Tiphaine Sancerni,Ophélie Renoult,Angèle Luby,Cédric Caradeuc,Véronique Lenoiret al. Frontiers in Immunology, 2022, 13, pp.960226. ⟨10.3389/fimmu.2022.960226⟩ Article dans une revue hal-03817349v1
Targeting Metabolism to Control Immune Responses in Cancer and Improve Checkpoint Blockade Immunotherapy Angèle Luby,Marie-Clotilde Alves-Guerra Cancers, 2021, 13 (23), pp.5912. ⟨10.3390/cancers13235912⟩ Article dans une revue hal-03798523v1
Mitochondrial Aurora kinase A induces mitophagy by interacting with MAP1LC3 and Prohibitin 2 Giulia Bertolin,Marie-Clotilde Alves-Guerra,Angélique Chéron,Agnès Burel,Claude Prigentet al. Life Science Alliance, 2021, 4 (6), pp.e202000806. ⟨10.26508/lsa.202000806⟩ Article dans une revue hal-03248135v1
The role of uncoupling protein 2 in macrophages and its impact on obesity-induced adipose tissue inflammation and insulin resistance Xanthe A.M.H. van Dierendonck,Tiphaine Sancerni,Marie-Clotilde Alves-Guerra,Rinke Stienstra Journal of Biological Chemistry, 2020, 295 (51), pp.17535-17548. ⟨10.1074/jbc.RA120.014868⟩ Article dans une revue hal-03418808v1
UCP2 Deficiency Increases Colon Tumorigenesis by Promoting Lipid Synthesis and Depleting NADPH for Antioxidant Defenses Esther Aguilar,Pauline Esteves,Tiphaine Sancerni,Véronique Lenoir,Thomas Aparicioet al. Cell Reports, 2019, 28 (9), pp.2306-2316.e5. ⟨10.1016/j.celrep.2019.07.097⟩ Article dans une revue inserm-02345411v1
β-catenin-activated hepatocellular carcinomas are addicted to fatty acids Nadia Senni,Mathilde Savall,David Cabrerizo Granados,Marie-Clotilde Alves-Guerra,Chiara Sartoret al. Gut, 2019, 68 (2), pp.322-334. ⟨10.1136/gutjnl-2017-315448⟩ Article dans une revue inserm-02532896v1
Glioblastoma Stem-Like Cells, Metabolic Strategy to Kill a Challenging Target Delphine Garnier,Ophélie Renoult,Marie-Clotilde Alves-Guerra,François Paris,Claire Pecqueur Frontiers in Oncology, 2019, 9, pp.118. ⟨10.3389/fonc.2019.00118⟩ Article dans une revue inserm-02240417v1
β-catenin-activated hepatocellular carcinomas are addicted to fatty acids Nadia Senni,Mathilde Savall,David Cabrerizo Granados,Marie-Clotilde Alves-Guerra,Chiara Sartoret al. Gut, 2019, 68 (2), pp.322-334. ⟨10.1136/gutjnl-2017-315448⟩ Article dans une revue hal-02347077v1
The mitochondrial uncoupling protein 2 gene is causal for the spontaneous polycystic liver diseases in mice Misa Hirose,Paul Schilf,Sarah Rohde,Yask Gupta,Tiphaine Sancerniet al. Mitochondrion, 2018, 42, pp.50-53. ⟨10.1016/j.mito.2017.10.011⟩ Article dans une revue hal-02347089v1
Aurora kinase A localises to mitochondria to control organelle dynamics and energy production Giulia Bertolin,Anne-Laure Bulteau,Marie-Clotilde Alves-Guerra,Agnes Burel,Marie-Thérèse Lavaultet al. eLife, 2018, 7, pp.e38111. ⟨10.7554/eLife.38111⟩ Article dans une revue hal-01862597v1
The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesity Julien Bricambert,Marie-Clotilde Alves-Guerra,Pauline Esteves,Carina Prip-Buus,Justine Bertrand-Michelet al. Nature Communications, 2018, 9 (1), ⟨10.1038/s41467-018-04361-y⟩ Article dans une revue hal-02122655v1
Mitochondrial Protein UCP2 Controls Pancreas Development Benjamin Broche,Selma Ben Fradj,Esther Aguilar,Tiphaine Sancerni,Matthieu Bénardet al. Diabetes, 2017, 67 (1), pp.78-84. ⟨10.2337/db17-0118⟩ Article dans une revue hal-02347094v1
Ionizing radiation induces long-term senescence in endothelial cells through mitochondrial respiratory complex II dysfunction and superoxide generation Audrey Lafargue,Charlotte Degorre,Isabelle Corre,Marie-Clotilde Alves-Guerra,Marie-Hélène Gaugleret al. Free Radical Biology and Medicine, 2017, 108, pp.750-759. ⟨10.1016/j.freeradbiomed.2017.04.019⟩ Article dans une revue inserm-01514403v1
Efficient Mitochondrial Glutamine Targeting Prevails Over Glioblastoma Metabolic Plasticity Kristell Oizel,Cynthia Chauvin,Lisa Oliver,Catherine Gratas,Fanny Geraldoet al. Clinical Cancer Research, 2017, 23 (20), ⟨10.1158/1078-0432.CCR-16-3102⟩ Article dans une revue inserm-01595798v1
UCPs, at the interface between bioenergetics and metabolism Frédéric Bouillaud,Marie-Clotilde Alves-Guerra,Daniel Ricquier Biochimica et Biophysica Acta - Molecular Cell Research, 2016, 1863 (10), pp.2443-2456. ⟨10.1016/j.bbamcr.2016.04.013⟩ Article dans une revue hal-02347140v1
Muscle expression of a malonyl-CoA-insensitive carnitine palmitoyltransferase-1 protects mice against high-fat/high-sucrose diet-induced insulin resistance Eliska Vavrova,Véronique Lenoir,Marie-Clotilde Alves-Guerra,Raphaël G. P. Denis,Julien Castelet al. AJP - Endocrinology and Metabolism, 2016, 311 (3), pp.E649-E660. ⟨10.1152/ajpendo.00020.2016⟩ Article dans une revue hal-02347127v1
NACK Is an Integral Component of the Notch Transcriptional Activation Complex and Is Critical for Development and Tumorigenesis Kelly Weaver,Marie-Clotilde Alves-Guerra,Ke Jin,Zhiqiang Wang,Xiaoqing Hanet al. Cancer Research, 2014, 74 (17), pp.4741-4751. ⟨10.1158/0008-5472.CAN-14-1547⟩ Article dans une revue hal-02347171v1
UCP2 induces metabolic reprogramming to inhibit proliferation of cancer cells Esteves Pauline,Claire Pecqueur,Alves-Guerra Marie-Clotilde Molecular & Cellular Oncology, 2014, 2 (1), ⟨10.4161/23723556.2014.975024⟩ Article dans une revue inserm-01207304v1
Analysis of Uncoupling Protein 2-Deficient Mice upon Anaesthesia and Sedation Revealed a Role for UCP2 in Locomotion Marie-Clotilde Alves-Guerra,Caroline Aheng,Claire Pecqueur,Sandrine Masscheleyn,Pierre Louis Tharauxet al. PLoS ONE, 2012, 7 (8), pp.e41846. ⟨10.1371/journal.pone.0041846⟩ Article dans une revue hal-02347202v1
Deletion of UCP2 in iNOS Deficient Mice Reduces the Severity of the Disease during Experimental Autoimmune Encephalomyelitis Caroline Aheng,Nathalie Ly,Mairead Kelly,Saleh Ibrahim,Daniel Ricquieret al. PLoS ONE, 2011, 6 (8), pp.e22841. ⟨10.1371/journal.pone.0022841⟩ Article dans une revue hal-02347213v1
UCP2, a metabolic sensor coupling glucose oxidation to mitochondrial metabolism? Claire Pecqueur,Clotilde Alves-Guerra,Daniel Ricquier,Frederic Bouillaud IUBMB Life, 2009, 61 (7), pp.762-767. ⟨10.1002/iub.188⟩ Article dans une revue hal-03055035v1
UCP2, a metabolic sensor coupling glucose oxidation to mitochondrial metabolism? Claire Pecqueur,Clotilde Alves-Guerra,Daniel Ricquier,Frédéric Bouillaud IUBMB Life, 2009, 61 (7), pp.762-767. ⟨10.1002/iub.188⟩ Article dans une revue hal-02347239v1
Mastermind-like 1 Is a specific coactivator of beta-catenin transcription activation and is essential for colon carcinoma cell survival. Alves-Guerra Marie-Clotilde,Ronchini Chiara,Capobianco Anthony J Cancer Research, 2007 Article dans une revue hal-02347311v1
Resistance to cerebral ischemic injury in UCP2 knockout mice: evidence for a role of UCP2 as a regulator of mitochondrial glutathione levels Fabienne de Bilbao,Denis Arsenijevic,Philippe Vallet,Ole Petter Hjelle,Ole Petter Ottersenet al. Journal of Neurochemistry, 2004, 89 (5), pp.1283-1292. ⟨10.1111/j.1471-4159.2004.02432.x⟩ Article dans une revue hal-03054815v1
Uncoupling Protein 2, but Not Uncoupling Protein 1, Is Expressed in the Female Mouse Reproductive Tract Sophie Rousset,Marie-Clotilde Alves-Guerra,Salma Ouadghiri-Bencherif,Leslie Kozak,Bruno Mirouxet al. Journal of Biological Chemistry, 2003, 278 (46), pp.45843-45847. ⟨10.1074/jbc.M306980200⟩ Article dans une revue hal-03054599v1
Bone Marrow Transplantation Reveals the in Vivo Expression of the Mitochondrial Uncoupling Protein 2 in Immune and Nonimmune Cells during Inflammation Marie-Clotilde Alves-Guerra,Sophie Rousset,Claire Pecqueur,Ziad Mallat,Julie Blancet al. Journal of Biological Chemistry, 2003, 278 (43), pp.42307-42312. ⟨10.1074/jbc.M306951200⟩ Article dans une revue hal-03054592v1
Uncoupling Protein 2, in Vivo Distribution, Induction upon Oxidative Stress, and Evidence for Translational Regulation Claire Pecqueur,Marie-Clotilde Alves-Guerra,Chantal Gelly,Corinne Lévi-Meyrueis,Elodie Couplanet al. Journal of Biological Chemistry, 2001, 276 (12), pp.8705-8712. ⟨10.1074/jbc.M006938200⟩ Article dans une revue hal-03054560v1
Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production Denis Arsenijevic,Hiroki Onuma,Claire Pecqueur,Serge Raimbault,Brian Manninget al. Nature Genetics, 2000, 26 (4), pp.435-439. ⟨10.1038/82565⟩ Article dans une revue hal-03054550v1
Transcriptional Activation of the Human ucp1 Gene in a Rodent Cell Line Maria del Mar Gonzalez-Barroso,Claire Pecqueur,Chantal Gelly,Daniel Sanchis,Marie-Clotilde Alves-Guerraet al. Journal of Biological Chemistry, 2000, 275 (41), pp.31722-31732. ⟨10.1074/jbc.M001678200⟩ Article dans une revue hal-03054399v1