Marie-Jeanne CLEMENT-LAI CHEONG

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Publications

From TDP-43/RNA complex formation to disease-linked TDP-43 aggregation through a structural and cellular approach

Yitian Feng , Vandana Joshi , Serhii Pankivskyi , Marie-Jeanne Clément , Juan-Carlos Rengifo-Gonzalez et al.

Nature Communications, In press, 17, pp.1631. ⟨10.1038/s41467-026-68346-y⟩

Article dans une revue hal-05517675v1

Using the structural diversity of RNA: protein interfaces to selectively target RNA with small molecules in cells: methods and perspectives

Aixiao Li , Ahmed Bouhss , Marie-Jeanne Clément , Cyril Bauvais , J. Paul Taylor et al.

Frontiers in Molecular Biosciences, 2023, 10, ⟨10.3389/fmolb.2023.1298441⟩

Article dans une revue hal-04485882v1
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FUS RRM regulates poly(ADP-ribose) levels after transcriptional arrest and PARP-1 activation on DNA damage

Evgeniya Mamontova , Marie-Jeanne Clément , Maria Sukhanova , Vandana Joshi , Ahmed Bouhss et al.

Cell Reports, 2023, 42 (10), pp.113199. ⟨10.1016/j.celrep.2023.113199⟩

Article dans une revue hal-04231448v1
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Structure and functional impact of glycosaminoglycan modification of HSulf-2 endosulfatase revealed by atomic force microscopy and mass spectrometry

Ilham Seffouh , Mélanie Bilong , Cédric Przybylski , Nesrine El Omrani , Salomé Poyer et al.

Scientific Reports, 2023, 13 (1), ⟨10.1038/s41598-023-49147-5⟩

Article dans une revue hal-04348199v1
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Targeting RNA:protein interactions with an integrative approach leads to the identification of potent YBX1 inhibitors

Krystel El Hage , Nicolas Babault , Olek Maciejak , Bénédicte Desforges , Pierrick Craveur et al.

eLife, 2023, 12, pp.e80387. ⟨10.7554/eLife.80387⟩

Article dans une revue hal-03955052v1
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Lin28, a major translation reprogramming factor, gains access to YB-1-packaged mRNA through its cold-shock domain

Anastasiia Samsonova , Krystel El Hage , Bénédicte Desforges , Vandana Joshi , Marie-Jeanne Clément et al.

Communications Biology, 2021, 4 (1), pp.359. ⟨10.1038/s42003-021-01862-3⟩

Article dans une revue hal-03176308v1
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The cooperative binding of TDP-43 to GU-rich RNA repeats antagonizes TDP-43 aggregation

Juan Carlos Rengifo-Gonzalez , Krystel El Hage , Marie-Jeanne Clément , Emilie Steiner , Vandana Joshi et al.

eLife, 2021, 10, pp.e.67605. ⟨10.7554/eLife.67605⟩

Article dans une revue hal-03343496v1
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YB-1 unwinds mRNA secondary structures in vitro and negatively regulates stress granule assembly in HeLa cells

Karina Budkina , Krystel El Hage , Marie-Jeanne Clément , Bénédicte Desforges , Ahmed Bouhss et al.

Nucleic Acids Research, 2021, 49 (17), pp.10061-10081. ⟨10.1093/nar/gkab748⟩

Article dans une revue hal-03333572v1

Identification of a small molecule splicing inhibitor targeting UHM domains

Asaki Kobayashi , Marie-Jeanne Clément , Pierrick Craveur , Krystel El Hage , Jean Matha Salone et al.

FEBS Journal, 2021, 289 (3), pp.682-698. ⟨10.1111/febs.16199⟩

Article dans une revue hal-03354012v1
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Catalysis and specificity of the polycondensation of aminopropyltrimethoxysilane on nucleic acids

Nathalie Jarroux , Marie-Jeanne Clément , Cédric Przybylski , Olek Maciejak , Patrick A. Curmi et al.

GSC Biological and Pharmaceutical Sciences, 2020, 13 (2), pp.290-299. ⟨10.30574/gscbps.2020.13.2.0332⟩

Article dans une revue hal-03702917v1
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YB-1, an abundant core mRNA-binding protein, has the capacity to form an RNA nucleoprotein filament: a structural analysis

Dmitry Kretov , Marie-Jeanne Clément , Guillaume Lambert , Dominique Durand , Dmitry Lyabin et al.

Nucleic Acids Research, 2019, 47 (6), pp.3127-3141. ⟨10.1093/nar/gky1303⟩

Article dans une revue hal-02114790v1

Templated polycondensation of aminopropyltrimethoxysilane on DNA

N. Jarroux , M.J. Clément , M. Gervais , S. Moriau , O. Maciejak et al.

European Polymer Journal, 2018, 103, pp.95-100. ⟨10.1016/J.EURPOLYMJ.2017.09.045⟩

Article dans une revue hal-02110163v1

A new model of short acceleration-based training improves exercise performance in old mice

R. Niel , M. Ayachi , L. Mille-Hamard , L. Le Moyec , P. Savarin et al.

Scandinavian Journal of Medicine and Science in Sports, 2017, 27 (12), pp.1576-1587. ⟨10.1111/sms.12809⟩

Article dans une revue hal-02167281v1

Radical Coupling Allows a Fast and Tuned Synthesis of Densely Packed Polyrotaxanes Involving γ-Cyclodextrins and Polydimethylsiloxane

François Blin , Cédric Przybylski , Véronique Bonnet , Marie-Jeanne Clément , Patrick. A. Curmi et al.

Macromolecules, 2016, 49 (9), pp.3232-3243. ⟨10.1021/acs.macromol.6b00492⟩

Article dans une revue hal-02065253v1
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Metabolomics with Nuclear Magnetic Resonance Spectroscopy in a Drosophila melanogaster Model of Surviving Sepsis

Veli Bakalov , Roland Amathieu , Mohamed N. Triba , Marie-Jeanne Clément , Laura Reyes Uribe et al.

Metabolites, 2016, 6 (4), pp.47. ⟨10.3390/metabo6040047⟩

Article dans une revue hal-02183588v1

Cucurbitacin I elicits the formation of actin/phospho-myosin II co-aggregates by stimulation of the RhoA/ROCK pathway and inhibition of LIM-kinase

Meryem Sari-Hassoun , Marie-Jeanne Clément , Imane Hamdi , Guillaume Bollot , Cyril Bauvais et al.

Biochemical Pharmacology, 2016, 102, pp.45-63. ⟨10.1016/j.bcp.2015.12.013⟩

Article dans une revue istex hal-02183418v1

The cellular activity of cucurbitacin I is inhibited by glycosylation

Ms Hassoun , Mj Clément , M Cailleret , N Jarroux , I Hamdi et al.

Planta Medica, 2014, 80 (16), pp.P1L129. ⟨10.1055/S-0034-1394786⟩

Article dans une revue hal-02112336v1
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Structural Basis for the Association of MAP6 Protein with Microtubules and Its Regulation by Calmodulin

Julien Lefèvre , Philippe Savarin , Pierre Gans , Loïc Hamon , Marie-Jeanne Clément et al.

Journal of Biological Chemistry, 2013, 288 (34), pp.24910-24922. ⟨10.1074/jbc.M113.457267⟩

Article dans une revue inserm-00858655v1

Mapping the Conformational Stability of Maltose Binding Protein at the Residue Scale Using Nuclear Magnetic Resonance Hydrogen Exchange Experiments

Céline Merstorf , Olek Maciejak , Jérôme Mathé , Manuela Pastoriza-Gallego , Bénédicte Thiebot et al.

Biochemistry, 2012, 51 (44), pp.8919-8930. ⟨10.1021/bi3003605⟩

Article dans une revue hal-02159344v1

Phosphorylation Controls the Interaction of the Connexin43 C-Terminal Domain with Tubulin and Microtubules

Amal Saidi Brikci-Nigassa , Marie-Jeanne Clément , Tâp Ha-Duong , Elisabeth Adjadj , Latifa Ziani et al.

Biochemistry, 2012, 51 (21), pp.4331-4342. ⟨10.1021/bi201806j⟩

Article dans une revue hal-02292202v1

The state of the guanosine nucleotide allosterically affects the interfaces of tubulin in protofilament

Joseph André , Marie-Jeanne Clément , Elisabeth Adjadj , Flavio Toma , Patrick Curmi et al.

Journal of Computer-Aided Molecular Design, 2012, 26 (4), pp.397-407. ⟨10.1007/s10822-012-9566-x⟩

Article dans une revue istex hal-02292225v1

NMR characterization and molecular modeling of fucoidan showing the importance of oligosaccharide branching in its anticomplementary activity

Marie-Jeanne Clément , Bérangère Tissot , Lionel Chevolot , Elisabeth Adjadj , Yuguo Du et al.

Glycobiology, 2010, 20 (7), pp.883-894. ⟨10.1093/glycob/cwq046⟩

Article dans une revue hal-01967562v1

The PN2-3 Domain of Centrosomal P4.1-associated Protein Implements a Novel Mechanism for Tubulin Sequestration

Anthony Cormier , Marie-Jeanne Clément , Marcel Knossow , Sylvie Lachkar , Philippe Savarin et al.

Journal of Biological Chemistry, 2009, 284 (11), pp.6909-6917. ⟨10.1074/jbc.M808249200⟩

Article dans une revue hal-02120593v1

The Stathmin-Derived I19L Peptide Interacts with FtsZ and Alters Its Bundling

Marie-Jeanne Clément , Boï-Trinh Kuoch , Tâp Ha-Duong , Vandana Joshi , Loic Hamon et al.

Biochemistry, 2009, 48 (41), pp.9734-9744. ⟨10.1021/bi900556a⟩

Article dans une revue hal-02295213v1

Benomyl and Colchicine Synergistically Inhibit Cell Proliferation and Mitosis: Evidence of Distinct Binding Sites for These Agents in Tubulin †

Marie-Jeanne Clément , Krishnan Rathinasamy , Elisabeth Adjadj , Flavio Toma , Patrick Curmi et al.

Biochemistry, 2008, 47 (49), pp.13016-13025. ⟨10.1021/bi801136q⟩

Article dans une revue istex hal-02295285v1

Both lipid environment and pH are critical for determining physiological solution structure of 3-D-conserved epitopes of the HIV-1 gp41-MPER peptide P1

Jérôme Coutant , Huifeng Yu , Marie-Jeanne Clément , Annette Alfsen , Flavio Toma et al.

FASEB Journal, 2008, 22 (12), pp.4338-4351. ⟨10.1096/fj.08-113142⟩

Article dans une revue hal-02295314v1

NMR assignment of PN2-3, a tubulin interaction subdomain of the CPAP protein

Marie-Jeanne Clément , Philippe Savarin , Jérôme Coutant , Flavio Toma , Patrick Curmi

Biomolecular NMR Assignments, 2008, 115, 2, pp.115-117. ⟨10.1007/s12104-008-9099-3⟩

Article dans une revue hal-02295383v1
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Toward a better understanding of the basis of the molecular mimicry of polysaccharide antigens by peptides: $the\ example\ of\ shigella\ flexneri\ 5A$

M.-J. Clement , A. Fortune , A. Phalipon , V. Marcel-Peyre , C. Simenel et al.

Journal of Biological Chemistry, 2006, 281 (4), pp.2317-32. ⟨10.1074/jbc.M510172200⟩

Article dans une revue pasteur-01115171v1

N-Terminal Stathmin-like Peptides Bind Tubulin and Impede Microtubule Assembly

Marie-Jeanne Clément , Isabelle Jourdain , Sylvie Lachkar , Philippe Savarin , Benoît Gigant et al.

Biochemistry, 2005, 44 (44), pp.14616-14625. ⟨10.1021/bi0512492⟩

Article dans une revue istex hal-02120587v1

Conformational studies of the O-specific polysaccharide of Shigella flexneri 5a and of four related synthetic pentasaccharide fragments using NMR and molecular modeling.

Marie-Jeanne Clément , Anne Imberty , Armelle Phalipon , Serge Pérez , Catherine Simenel et al.

Journal of Biological Chemistry, 2003, 278 (48), pp.47928-36. ⟨10.1074/jbc.M308259200⟩

Article dans une revue pasteur-00369608v1

Convergent synthesis, NMR and conformational analysis of tetra-and petasaccharide haptens of the Shigella flexneri serotype 5a O-specific polysaccharide

Laurence A Mulard , Marie-Jeanne Clément , Anne Imberty , Muriel Delepierre

European Journal of Organic Chemistry, 2002, 15, pp.2486-2498. ⟨10.1002/1099-0690(200208)2002:15<2486::AID-EJOC2486>3.0.CO;2-E⟩

Article dans une revue istex pasteur-00371353v1

Synthesis and NMR study of a linear pentasaccharide fragment of the Shigella Flexneri 5a O-specific polysaccharide

Laurence A Mulard , Marie-Jeanne Clement , Fabienne Ségat-Dioury , Muriel Delepierre

Tetrahedron, 2002, 58 (13), pp.2953-2604. ⟨10.1016/S0040-4020(02)00148-5⟩

Article dans une revue istex pasteur-00371338v1