Marie Lopez

Identifiants chercheurs

IdHAL :

marie-lopez

ORCID :

0000-0001-7479-4657

IdRef :

071198946

Présentation

Publications

Article dans une revue (36)

Selective disruption of DNMT1/ELK1 interactions induces DGKI re-expression and promotes temozolomide sensitivity of MGMT(methylated)/DGKI(methylated) glioblastoma Jean-Maxime Besson,Amandine Etcheverry,Arulraj Nadaradjane,Gwenola Bougras-Cartron,Marc Aubryet al. Clinical Epigenetics, 2025, 17 (1), pp.146. ⟨10.1186/s13148-025-01943-8⟩ Article dans une revue hal-05249512v1
Rational Design and Synthesis of Highly Stable Haloflavanone DNA Methyltransferase Inhibitors Inducing Tumor Suppressor Gene Re-expression in Cancer Cells Francesco Calzaferri,Hiba Daher,Julie Gilbert,Yinshan Yang,Marine Tauzietet al. Journal of Medicinal Chemistry, 2025, 68 (11), pp.10704-10721. ⟨10.1021/acs.jmedchem.4c02075⟩ Article dans une revue pasteur-05248866v1
Combination of MLo-1508 with sunitinib for the experimental treatment of papillary renal cell carcinoma Ângela Marques-Magalhães,Filipa Moreira-Silva,Inês Graça,Paula Dias,Margareta Correiaet al. Frontiers in Oncology, 2025, 15, pp.1399956. ⟨10.3389/fonc.2025.1399956⟩ Article dans une revue pasteur-05248870v1
Introduction of epigenetic variation contribute to resistance against the human parasite Schistosoma mansoni Nelia Luviano-Aparicio,Marie Lopez,Bart Haegeman,Pierick Mouginot,Cristian Chaparroet al. Epigenetics & Chromatin, 2025, 18 (1), pp.43. ⟨10.1186/s13072-025-00607-4⟩ Article dans une revue hal-05172481v1
3-Halo-3-nitro-aza/thioflavanones: DNMT inhibitors with a two-site binding mode in the hDNMT3A catalytic pocket Alexandra Serhouni,Francesco Calzaferri,Yannick Bessina,Arie van Der Lee,Paola B Arimondoet al. Bioorganic and Medicinal Chemistry, 2024, 118, pp.117988. ⟨10.1016/j.bmc.2024.117988⟩ Article dans une revue hal-04817890v1
Epidrugs as Promising Tools to Eliminate Plasmodium falciparum Artemisinin-Resistant and Quiescent Parasites Thibaud Reyser,Lucie Paloque,Michel Nguyen,Jean-Michel Augereau,Matthew John Fuchteret al. Pharmaceutics, 2023, 15 (10), pp.2440. ⟨10.3390/pharmaceutics15102440⟩ Article dans une revue hal-04269105v1
SCF‐ChemBio: Chemical Biology Tour de France Marie Lopez,Yung‐sing Wong,Christophe Biot,Boris Vauzeilles ChemBioChem, 2023, ChemBioChem, 24 (10), ⟨10.1002/cbic.202300075⟩ Article dans une revue hal-04199854v1
PSL Chemical Biology Symposia Third Edition: A Branch of Science in its Explosive Phase Leeroy Baron,Justine Hadjerci,Leishemba Thoidingjam,Marina Plays,Romain Bucciet al. ChemBioChem, 2023, 24 (8), pp.e202300093. ⟨10.1002/cbic.202300093⟩ Article dans une revue hal-04092530v1
Unexpected One‐Pot Formation of Lactam Oximes from Amino‐Hydroxamic Esters Santiago Lascano,Arie van der Lee,Marie Lopez European Journal of Organic Chemistry, 2022, 2022 (21), ⟨10.1002/ejoc.202200102⟩ Article dans une revue hal-03871396v1
Anti-neoplastic and demethylating activity of a newly synthetized flavanone-derived compound in Renal Cell Carcinoma cell lines Ângela Marques-Magalhães,Inês Graça,Vera Miranda-Gonçalves,Rui Henrique,Marie Lopezet al. Biomedicine and Pharmacotherapy, 2021, 141, pp.111681. ⟨10.1016/j.biopha.2021.111681⟩ Article dans une revue pasteur-03411793v1
Targeting Germ Cell Tumors with the Newly Synthesized Flavanone-Derived Compound MLo1302 Efficiently Reduces Tumor Cell Viability and Induces Apoptosis and Cell Cycle Arrest João Lobo,Ana Rita Cardoso,Vera Miranda-Gonçalves,Leendert H J Looijenga,Marie Lopezet al. Pharmaceutics, 2021, Special Issue Cancer Mechanisms and Emerging Therapies, 13 (1), pp.73. ⟨10.3390/pharmaceutics13010073⟩ Article dans une revue pasteur-03105846v1
The methylome of Biomphalaria glabrata and other mollusks: enduring modification of epigenetic landscape and phenotypic traits by a new DNA methylation inhibitor Nelia Luviano,Marie Lopez,Fleur Gawehns,Cristian Chaparro,Paola B Arimondoet al. Epigenetics & Chromatin, 2021, 14 (1), pp.48. ⟨10.1186/s13072-021-00422-7⟩ Article dans une revue pasteur-03427775v2
Bisubstrate-Type Chemical Probes Identify GRP94 as a Potential Target of Cytosine-Containing Adenosine Analogs Dany Pechalrieu,Fanny Assemat,Ludovic Halby,Marlene Marcellin,Pengrong Yanet al. ACS Chemical Biology, 2020, 15 (4), pp.952-961. ⟨10.1021/acschembio.9b00965⟩ Article dans une revue pasteur-03026521v1
Synthesis of novel 3-halo-3-nitroflavanones and their activities as DNA methyltransferase inhibitors in cancer cells Dany Pechalrieu,Daniel Dauzonne,Paola Arimondo,Marie Lopez European Journal of Medicinal Chemistry, 2020, pp.111829. ⟨10.1016/j.ejmech.2019.111829⟩ Article dans une revue hal-02394113v1
Natural Products and Chemical Biology Tools: Alternatives to Target Epigenetic Mechanisms in Cancers Santiago Lascano,Marie Lopez,Paola B Arimondo Chemical Record, 2018, 18 (12), pp.1854-1876. ⟨10.1002/tcr.201800133⟩ Article dans une revue hal-03082748v1
Compounds for use in the treatment of mycobacterial infections: a patent evaluation (WO2014049107A1) Dany Pechalrieu,Marie Lopez Expert Opinion on Therapeutic Patents, 2015, 25 (6), pp.729-735. ⟨10.1517/13543776.2015.1021333⟩ Article dans une revue hal-02399895v1
Oxo- and thiooxo-imidazo[1,5-c]pyrimidine molecule library: Beyond their interest in inhibition of Brucella suis histidinol dehydrogenase, a powerful protection tool in the synthesis of histidine analogues François Turtaut,Marie Lopez,Safia Ouahrani-Bettache,Stephan Köhler,Jean-Yves Winum Bioorganic and Medicinal Chemistry Letters, 2014, 24 (21), pp.5008-5010. ⟨10.1016/j.bmcl.2014.09.020⟩ Article dans une revue istex hal-02425098v1
Synthesis of sulfonamide-conjugated glycosyl-amino acid building blocks Marie Lopez,Laurent Bornaghi,Sally-Ann Poulsen Carbohydrate Research, 2014, 386, pp.78-85. ⟨10.1016/j.carres.2013.08.017⟩ Article dans une revue hal-03130488v1
Structural basis for the rational design of new anti-Brucella agents: The crystal structure of the C366S mutant of l-histidinol dehydrogenase from Brucella suis Katia d'Ambrosio,Marie Lopez,Nina Dathan,Safia Ouahrani-Bettache,Stephan Köhleret al. Biochimie, 2014, 97, pp.114-120. ⟨10.1016/j.biochi.2013.09.028⟩ Article dans une revue istex hal-02425093v1
Synthesis of acylated glycoconjugates as templates to investigate in vitro biopharmaceutical properties Cindy Carroux,Janina Moeker,Josephine Motte,Marie Lopez,Laurent Bornaghiet al. Bioorganic and Medicinal Chemistry Letters, 2013, 23 (2), pp.455-459. ⟨10.1016/j.bmcl.2012.11.056⟩ Article dans une revue hal-03130067v1
Antimalarial activity of compounds comprising a primary benzene sulfonamide fragment Katherine Andrews,Gillian Fisher,Subathdrage D.M. Sumanadasa,Tina Skinner-Adams,Janina Moekeret al. Bioorganic and Medicinal Chemistry Letters, 2013, 23 (22), pp.6114-6117. ⟨10.1016/j.bmcl.2013.09.015⟩ Article dans une revue hal-03130480v1
Zinc metalloenzymes as new targets against the bacterial pathogen Brucella Marie Lopez,Stephan Köhler,Jean-Yves Winum Journal of Inorganic Biochemistry, 2012, 111, pp.138-145. ⟨10.1016/j.jinorgbio.2011.10.019⟩ Article dans une revue istex hal-02424989v1
Design and synthesis of thiourea compounds that inhibit transmembrane anchored carbonic anhydrases Janina Moeker,Kanae Teruya,Sabine Rossit,Brendan Wilkinson,Marie Lopezet al. Bioorganic and Medicinal Chemistry Letters, 2012, 20 (7), pp.2392-2404. ⟨10.1016/j.bmc.2012.01.052⟩ Article dans une revue hal-03130049v1
Chemo-enzymatic synthesis of xylogluco-oligosaccharides and their interactions with cellulose Marie Lopez,Sébastien Fort,Herve Bizot,Alain Buléon,Hugues Driguez Carbohydrate Polymers, 2012, 88 (1), pp.185-193. ⟨10.1016/j.carbpol.2011.11.085⟩ Article dans une revue istex hal-02119250v1
Promiscuity of Carbonic Anhydrase II. Unexpected Ester Hydrolysis of Carbohydrate-Based Sulfamate Inhibitors Marie Lopez,Hoan Vu,Conan Wang,Maarten Wolf,Gerrit Groenhofet al. Journal of the American Chemical Society, 2011, 133 (45), pp.18452-18462. ⟨10.1021/ja207855c⟩ Article dans une revue hal-03129971v1
Targeting hypoxic tumor cell viability with carbohydrate-based carbonic anhydrase IX and XII inhibitors. Jason C Morris,Johanna Chiche,Caroline Grellier,Marie Lopez,Laurent F Bornaghiet al. Journal of Medicinal Chemistry, 2011, 54 (19), pp.6905-18. ⟨10.1021/jm200892s⟩ Article dans une revue hal-00756639v1
Design, Synthesis, and Biological Evaluation of Novel Carbohydrate-Based Sulfamates as Carbonic Anhydrase Inhibitors Marie Lopez,Jonathan Trajkovic,Laurent Bornaghi,Alessio Innocenti,Daniela Vulloet al. Journal of Medicinal Chemistry, 2011, 54 (5), pp.1481-1489. ⟨10.1021/jm101525j⟩ Article dans une revue hal-03129906v1
Synthesis of Sulfonamide-Bridged Glycomimetics Marie Lopez,Laurent Bornaghi,Hugues Driguez,Sally-Ann Poulsen Journal of Organic Chemistry, 2011, 76 (9), pp.2965-2975. ⟨10.1021/jo2001269⟩ Article dans une revue hal-03129918v1
Sulfonamide Linked Neoglycoconjugates−A New Class of Inhibitors for Cancer-Associated Carbonic Anhydrases Marie Lopez,Laurent F Bornaghi,Alessio Innocenti,Daniela Vullo,Susan A. Charmanet al. Journal of Medicinal Chemistry, 2010, 53 (7), pp.2913-2926. ⟨10.1021/jm901888x⟩ Article dans une revue hal-03128749v1
Synthesis of N-Propargyl Iminosugar Scaffolds for Compound Library Generation using Click Chemistry Brendan L. Wilkinson,Laurent F Bornaghi,Marie Lopez,Peter C. Healy,Sally-Ann Poulsenet al. Australian Journal of Chemistry, 2010, 63 (5), pp.821. ⟨10.1071/CH09426⟩ Article dans une revue hal-03129177v1
Carbonic Anhydrase Inhibitors Developed Through &quot;Click Tailing Marie Lopez,Adam J. Salmon,Claudiu T. Supuran,Sally-Ann Poulsen Current Pharmaceutical Design, 2010, 16 (29), pp.3277-3287. ⟨10.2174/138161210793429869⟩ Article dans une revue hal-03129902v1
Synthesis of S -Glycosyl Primary Sulfonamides Marie Lopez,Nicolas Drillaud,Laurent F Bornaghi,Sally-Ann Poulsen Journal of Organic Chemistry, 2009, 74 (7), pp.2811-2816. ⟨10.1021/jo9000367⟩ Article dans une revue hal-03128559v1
Inhibition of carbonic anhydrase isozymes with benzene sulfonamides incorporating thio, sulfinyl and sulfonyl glycoside moieties Mathilde Singer,Marie Lopez,Laurent F Bornaghi,Alessio Innocenti,Daniela Vulloet al. Bioorganic and Medicinal Chemistry Letters, 2009, 19 (8), pp.2273-2276. ⟨10.1016/j.bmcl.2009.02.086⟩ Article dans une revue hal-03128552v1
S -Glycosyl Primary Sulfonamides−A New Structural Class for Selective Inhibition of Cancer-Associated Carbonic Anhydrases Marie Lopez,Blessy Paul,Andreas Hoffmann,Julia Morizzi,Quoc K. Wuet al. Journal of Medicinal Chemistry, 2009, 52 (20), pp.6421-6432. ⟨10.1021/jm900914e⟩ Article dans une revue hal-03128575v1
The European Sturgeon Acipenser sturio is a suitable host for the glochidia of the freshwater pearl mussel Margaritifera auricularia Marie Lopez,C.R. Altabla,Thierry Rouault,E. Gisbert Journal of Molluscan Studies, 2007, 73, pp.207-209 Article dans une revue hal-02589551v1
Glycosynthase activity of hybrid aspen xyloglucan endo-transglycosylase PttXET16-34 nucleophile mutants. Kathleen Piens,Anna-Maria Henriksson,Fredrika Gullfot,Marie Lopez,Régis Fauréet al. Organic & Biomolecular Chemistry, 2007, 5 (24), pp.3971-8. ⟨10.1039/b714570e⟩ Article dans une revue istex hal-00623924v1

Chapitre d'ouvrage (3)

Inhibitors of DNA Methylation Marie Lopez,Julie Gilbert,Jean Contreras,Ludovic Halby,Paola B Arimondo DNA Methyltransferases - Role and Function [Second Edition], 1389, pp.471-513, 2022, Advances in Experimental Medicine and Biology, 978-3-031-11454-0 (eBook). ⟨10.1007/978-3-031-11454-0_17⟩ Chapitre d'ouvrage hal-04269122v1
Drug Discovery Methods Marie Lopez,Maxime Leroy,Chantal Etiévant,Frédéric Ausseil,Alexandre Gagnonet al. Drug Discovery in Cancer Epigenetics, Elsevier, pp.63-95, 2016, ⟨10.1016/b978-0-12-802208-5.00003-5⟩ Chapitre d'ouvrage hal-02399880v1
DNA Methyltransferase Inhibitors: Development and Applications Marie Lopez,Ludovic Halby,Paola Arimondo DNA Methyltransferases - Role and Function, pp.431-473, 2016, ⟨10.1007/978-3-319-43624-1_16⟩ Chapitre d'ouvrage hal-02399858v1

Thèse (1)

Hydrolyses et Synthèse chimio-enzymatiques appliquées à la préparation de xyloglucooligosaccharides pour l'étude des interactions xyloglucanes-cellulose Marie Lopez Chimie. Université Joseph-Fourier - Grenoble I, 2007. Français. ⟨NNT : ⟩ Thèse tel-00420010v1