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Maryline Beyler



Design of Bifunctional Pyclen-Based Lanthanide Luminescent Bioprobes for Targeted Two-Photon Imaging

Nadège Hamon , Lucile Bridou , Margaux Roux , Olivier Maury , Raphaël Tripier
Journal of Organic Chemistry, 2023, 88 (13), pp.8286-8299. ⟨10.1021/acs.joc.3c00287⟩
Journal articles hal-04254162v1
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« New Modalities in Cancer Imaging and Therapy » XVe édition de l’atelier organisé par le réseau « Vectorisation, Imagerie, Radiothérapies » du Cancéropôle Grand-Ouest, 5–8 octobre 2022, Erquy, France

Françoise Léost , Jacques Barbet , Maryline Beyler , Michel Chérel , Grégory Delpon
Bulletin du Cancer, 2023, 110 (12), pp.1322-1331. ⟨10.1016/j.bulcan.2023.08.007⟩
Journal articles hal-04279280v1

Pyclen-Based Ligands Bearing Pendant Picolinate Arms for Gadolinium Complexation

Gwladys Nizou , Enikő Molnár , Nadège Hamon , Ferenc Krisztián Kálmán , Olivier Fougère
Inorganic Chemistry, 2021, ⟨10.1021/acs.inorgchem.0c03277⟩
Journal articles hal-03122227v1

Design of polyazamacrocyclic Gd3+ theranostic agents combining magnetic resonance imaging and two-photon photodynamic therapy

Laura Abad Galán , Nadege Hamon , Christophe Nguyen , Eniko Molnar , János Kiss
Inorganic Chemistry Frontiers, 2021, ⟨10.1039/D0QI01519A⟩
Journal articles hal-03137794v1

Tuning the lipophilic nature of pyclen-based 90Y3+ radiopharmaceuticals for β-radiotherapy

Mariane Le Fur , Olivier Fougère , Nicolas Lepareur , Olivier Rousseaux , Raphaël Tripier
Metallomics, 2021, 13 (12), ⟨10.1093/mtomcs/mfab070⟩
Journal articles hal-03468303v1

A different approach: highly encapsulating macrocycles being used as organic tectons in the building of CPs

Agustín Esteban-Muriel , Carlos Laglera-Gándara , Marta Mato-Iglesias , Raphaël Tripier , Maryline Beyler
CrystEngComm, 2020, ⟨10.1039/D0CE01499K⟩
Journal articles hal-03053378v1

Pyclen-Based Ln(III) Complexes as Highly Luminescent Bioprobes for In Vitro and In Vivo One- and Two-Photon Bioimaging Applications

Nadège Hamon , Amandine Roux , Maryline Beyler , Jean-Christophe Mulatier , Chantal Andraud
Journal of the American Chemical Society, 2020, ⟨10.1021/jacs.0c03496⟩
Journal articles hal-02616978v1
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Cationic Biphotonic Lanthanide Luminescent Bioprobes Based on Functionalized Cross‐Bridged Cyclam Macrocycles.

Jonathan Mendy , Anh Thy Bui , Amandine Roux , Jean-Christophe Mulatier , Damien Curton
ChemPhysChem, 2020, 21 (10), pp.1036-1043. ⟨10.1002/cphc.202000085⟩
Journal articles hal-02533027v1

Enabling Indium Channels for Mass Cytometry by Using Reinforced Cyclam-Based Chelating Polylysine

Laura Grenier , Maryline Beyler , Taunia Closson , Nick Zabinyakov , Alexandre Bouzekri
Bioconjugate Chemistry, inPress, ⟨10.1021/acs.bioconjchem.0c00267⟩
Journal articles hal-02925847v1
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Picolinate-Appended Tacn Complexes for Bimodal Imaging: radiolabeling, relaxivity, photophysical and electrochemical studies

Amaury Guillou , Margaux Galland , Amandine Roux , Balázs Váradi , Réka Anna Gogolák
Journal of Inorganic Biochemistry, 2019, Epub ahead of print. ⟨10.1016/j.jinorgbio.2019.110978⟩
Journal articles inserm-02436868v1

Highly stable and inert complexation of Indium(III) by reinforced cyclam dipicolinate and a bifunctional derivative for bead encoding in mass cytometry

Laura Grenier , Maryline Beyler , Carlos Platas-Iglesias , Taunia Closson , David Esteban Gómez
Chemistry - A European Journal, 2019, ⟨10.1002/chem.201903969⟩
Journal articles hal-02281241v1

Combining a pyclen framework with conjugated antenna for the design of europium and samarium luminescent bioprobes

Nadège Hamon , Margaux Galland , Mariane Le Fur , Amandine Roux , Alain Duperray
Chemical Communications, 2018, 54 (48), pp.6173-6176. ⟨10.1039/c8cc02035c⟩
Journal articles hal-01803849v1

Stable and Inert Yttrium(III) Complexes with Pyclen-Based Ligands Bearing Pendant Picolinate Arms: Toward New Pharmaceuticals for β-Radiotherapy

Mariane Le Fur , Maryline Beyler , Enikő Molnár , Olivier Fougere , David Esteban-Gómez
Inorganic Chemistry, 2018, 57 (4), pp.2051-2063. ⟨10.1021/acs.inorgchem.7b02953⟩
Journal articles hal-01701694v1

A Coordination Chemistry Approach to Fine-Tune the Physicochemical Parameters of Lanthanide Complexes Relevant to Medical Applications

Mariane Le Fur , Eniko Molnar , Maryline Beyler , Ferenc K Kalman , Olivier Fougère
Chemistry - A European Journal, 2018, Chemistry, an European journal, 24 (13), pp.3127-3131. ⟨10.1002/chem.201705528⟩
Journal articles hal-01665222v1

Expanding the Family of Pyclen-Based Ligands Bearing Pendant Picolinate Arms for Lanthanide Complexation

Mariane Le Fur , Enikő Molnár , Maryline Beyler , Olivier Fougere , David Esteban-Gomez
Inorganic Chemistry, 2018, ⟨10.1021/acs.inorgchem.8b00598⟩
Journal articles hal-01803853v1
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Kinetics are crucial when targeting copper ions to fight Alzheimer's disease: an illustration with azamacrocyclic ligands

Amandine Conte-Daban , Maryline Beyler , Raphaël Tripier , Christelle Hureau
Chemistry - A European Journal, 2018, 24 (33), pp.8447-8452. ⟨10.1002/chem.201801520⟩
Journal articles hal-01764900v1

Near infrared two photon imaging using a bright cationic Yb(III) bioprobe spontaneously internalized into live cells

Anh Thy Bui , Maryline Beyler , Alexei Grichine , Alain Duperray , Jean-Christophe Mulatier
Chemical Communications, 2017, 53, pp.6005-6008 ⟨10.1039/C7CC02835K⟩
Journal articles hal-01526221v1

The role of the capping bond effect on pyclen Y-nat(3+)/Y-90(3+) chelates: full control of the regiospecific N-functionalization makes the difference

Mariane Le Fur , Maryline Beyler , Eniko Molnar , Olivier Fougere , David Esteban-Gomez
Chemical Communications, 2017, 53 (69), pp.9534-9537. ⟨10.1039/c7cc05088g⟩
Journal articles hal-01616222v1
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Investigation of the complexation of nat Zr(IV) and 89 Zr(IV) by hydroxypyridinones for the development of chelators for PET imaging applications

François Guérard , Maryline Beyler , Y.-S Lee , Raphaël Tripier , Jean-François Gestin
Dalton Transactions, 2017, 46, pp.4749-4758. ⟨10.1039/c6dt04625h⟩
Journal articles inserm-01496515v1
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Cyclam te1pa for 64 Cu PET imaging. Bioconjugation to antibody, radiolabeling and preclinical application in xenografted colorectal cancer

Mathieu Frindel , Patricia Le Saec , Maryline Beyler , Anne-Sophie Navarro , Catherine Sai-Maurel
RSC Advances, 2017, 7, pp.9272-9283. ⟨10.1039/c6ra26003a⟩
Journal articles inserm-01463724v1

Pyclen Tri- n -butylphosphonate Ester as Potential Chelator for Targeted Radiotherapy: From Yttrium(III) Complexation to 90 Y Radiolabeling

Mariane Le Fur , Maryline Beyler , Nicolas Lepareur , Olivier Fougère , Carlos Platas-Iglesias
Inorganic Chemistry, 2016, 55 (16), pp.8003 - 8012. ⟨10.1021/acs.inorgchem.6b01135⟩
Journal articles hal-01517774v1

Intracellular Transport Studies of Picolinate Macrocyclic Copper and Lanthanide Complexes

Diego Santo Domingo Porqueras , Maryline Beyler , Raphaël Tripier , Milena Salerno
ChemistrySelect, 2016, 1 (15), pp.4423 - 4429. ⟨10.1002/slct.201600990⟩
Journal articles hal-01518187v1

Cyclams with Ambidentate Methylthiazolyl Pendants for Stable, Inert, and Selective Cu(II) Coordination

Aurora Rodríguez-Rodríguez , Zakaria Halime , Luís M. P. Lima , Maryline Beyler , David Deniaud
Inorganic Chemistry, 2016, 55 (2), pp.619-632. ⟨10.1021/acs.inorgchem.5b01779⟩
Journal articles hal-01517782v1

Cationic Two-Photon Lanthanide Bioprobes Able to Accumulate in Live Cells

Anh Thy Bui , Maryline Beyler , Yuan-Yuan Liao , Alexei Grichine , Alain Duperray
Inorganic Chemistry, 2016, 55 (14), pp.7020 - 7025. ⟨10.1021/acs.inorgchem.6b00891⟩
Journal articles hal-01517789v1

Improving the stability and inertness of Cu( ii ) and Cu( i ) complexes with methylthiazolyl ligands by tuning the macrocyclic structure

Mariane Le Fur , Maryline Beyler , Nicolas Le Poul , Luís M. P. Lima , Yves Le Mest
Dalton Transactions, 2016, 45 (17), pp.7406 - 7420. ⟨10.1039/C6DT00385K⟩
Journal articles hal-01518185v1

Targeting amyloid peptide using metal complexes

Diego Santo Domingo Porqueras , Raphaël Tripier , Maryline Beyler , Milena Salerno
Alzheimer's & Dementia : the Journal of the Alzheimer's Association, 2015, 11 (7), ⟨10.1016/j.jalz.2015.06.355⟩
Journal articles hal-01538483v1

Investigating the Complexation of the Pb 2+ /Bi 3+ Pair with Dipicolinate Cyclen Ligands

Luís M. P. Lima , Maryline Beyler , Rita Delgado , Carlos Platas-Iglesias , Raphaël Tripier
Inorganic Chemistry, 2015, 54 (14), pp.7045 - 7057. ⟨10.1021/acs.inorgchem.5b01079⟩
Journal articles hal-01517764v1

A [two-step/one week] synthesis of C-functionalized homocyclens and cyclams. Application to the preparation of conjugable BCAs without chelating properties alteration

Nathalie Camus , Zakaria Halime , Nathalie Le Bris , Hélène Bernard , Maryline Beyler
RSC Advances, 2015, 5 (104), pp.85898 - 85910. ⟨10.1039/c5ra17133d⟩
Journal articles hal-01517785v1

Stable Mn 2+ , Cu 2+ and Ln 3+ complexes with cyclen-based ligands functionalized with picolinate pendant arms

Aurora Rodríguez-Rodríguez , Zoltán Garda , Erika Ruscsák , David Esteban-Gómez , Andrés de Blas
Dalton Transactions, 2015, 44 (11), pp.5017 - 5031. ⟨10.1039/C4DT02985B⟩
Journal articles hal-01518182v1

Straightforward and mild deprotection methods of N-mono- and N1,N7-functionalised bisaminal cyclens

Fatima Oukhatar , Maryline Beyler , Raphaël Tripier
Tetrahedron, 2015, 71 (23), pp.3857 - 3862. ⟨10.1016/j.tet.2015.04.021⟩
Journal articles hal-01518184v1

Supramolecular Luminescent Lanthanide Dimers for Fluoride Sequestering and Sensing

Hong Tao Liu , Aline M. Nonat , Maryline Beyler , Martin Regueiro-Figueroa , Katia Nchimi Nono
Angewandte Chemie, 2014, 53 (28), pp.7259-7263. ⟨10.1002/anie.201404847⟩
Journal articles hal-01151723v1

H2Me-do2pa: an attractive chelator with fast, stable and inert nat Bi 3+ and 213 Bi 3+ complexation for potential α-radioimmunotherapy applications

Luís M. P. Lima , Maryline Beyler , Fatima Oukhatar , Patricia Le Saec , Alain Faivre-Chauvet
Chemical Communications, 2014, 50 (82), pp.12371 - 12374. ⟨10.1039/C4CC05529B⟩
Journal articles hal-01517757v1

Pentacoordinate iron complexes as functional models of the distal iron in [FeFe] hydrogenases

Maryline Beyler , Salah Ezzaher , Michael Karnahl , Marie-Pierre Santoni , Reiner Lomoth
Chemical Communications, 2011, 47 (42), pp.6005 - 6008. ⟨10.1039/C1CC14449A⟩
Journal articles hal-01561943v1

Coordination Chemistry-Assembled Porphyrinic Catenanes

Maryline Beyler , Valérie Heitz , Jean-Pierre Sauvage
Journal of the American Chemical Society, 2010, 132 (12), pp.4409 - 4417. ⟨10.1021/ja910747h⟩
Journal articles hal-01618639v1

Quantitative formation of a tetraporphyrin [2]catenane via copper and zinc coordination

Maryline Beyler , Valérie Heitz , Jean-Pierre Sauvage
Chemical Communications, 2008, 42, ⟨10.1039/B811013A⟩
Journal articles hal-01561945v1