Matteo Mangoni

51
Documents

Présentation

thematique de recherche

Publications

Publications

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Computational modelling of mouse atrio ventricular node action potential and automaticity

Chiara Bartolucci , Pietro Mesirca , Eugenio Ricci , Clara Sales‐bellés , Eleonora Torre et al.
The Journal of Physiology, 2024, 602 (19), pp.4821-4847. ⟨10.1113/JP285950⟩
Article dans une revue hal-04780628 v1
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Selective blockade of Ca$_V$1.2 (α1C) versus Ca$_V$1.3 (α1D) L-type calcium channels by the black mamba toxin calciseptine

Pietro Mesirca , Jean Chemin , Christian Barrère , Eleonora Torre , Laura Gallot et al.
Nature Communications, 2024, 15 (1), pp.54. ⟨10.1038/s41467-023-43502-w⟩
Article dans une revue hal-04385916 v1
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State-of-the-Art Differentiation Protocols for Patient-Derived Cardiac Pacemaker Cells

Eleonora Torre , Matteo Mangoni , Alain Lacampagne , Albano Meli , Pietro Mesirca
International Journal of Molecular Sciences, 2024, 25 (6), pp.3387. ⟨10.3390/ijms25063387⟩
Article dans une revue (article de synthèse) hal-04524782 v1
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Cardiac GR Mediates the Diurnal Rhythm in Ventricular Arrhythmia Susceptibility

Roman Tikhomirov , Robert Oakley , Cali Anderson , Yirong Xiang , Sami Al Othman et al.
Circulation Research, 2024, 134 (10), pp.1306-1326. ⟨10.1161/CIRCRESAHA.123.323464⟩
Article dans une revue hal-04524430 v1
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Optical Control of Cardiac Rhythm by In Vivo Photoactivation of an ERG Channel Peptide Inhibitor

Jérôme Montnach , Hugo Millet , Antoine Persello , Hervé Meudal , Stephan de Waard et al.
Circulation Research, 2023, 133 (6), pp.535-538. ⟨10.1161/CIRCRESAHA.123.322880⟩
Article dans une revue hal-04225427 v1

Optical Control of Cardiac Rhythm by In Vivo Photoactivation of an ERG Channel Peptide Inhibitor

Jérôme Montnach , Hugo Millet , Antoine Persello , Hervé Meudal , Stephan de Waard et al.
Circulation Research, 2023, 133 (6), pp.535-538. ⟨10.1161/CIRCRESAHA.123.322880⟩
Article dans une revue hal-04634027 v1
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High-speed optical mapping of heart and brain voltage activities in zebrafish larvae exposed to environmental contaminants

Solène Micou , Isabel Forner-Piquer , Noémie Cresto , Tess Zassot , Aurélien Drouard et al.
Environmental Technology and Innovation, 2023, 31, pp.103196. ⟨10.1016/j.eti.2023.103196⟩
Article dans une revue hal-04240603 v1
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Lipopolysaccharide-induced sepsis impairs M2R-GIRK signaling in the mouse sinoatrial node

Niroj Shrestha , Klaus Zorn-Pauly , Pietro Mesirca , Chintan N Koyani , Gerald Wölkart et al.
Proceedings of the National Academy of Sciences of the United States of America, 2023, 120 (28), pp.e2210152120. ⟨10.1073/pnas.2210152120⟩
Article dans une revue hal-04271641 v1
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Impact of stress on cardiac phenotypes in mice harboring an ankyrin-B disease variant

Michael J Wallace , Nipun Malhotra , Juan Ignacio Elio Mariángelo , Tyler L Stevens , Lindsay J Young et al.
Journal of Biological Chemistry, 2023, 299 (6), pp.104818. ⟨10.1016/j.jbc.2023.104818⟩
Article dans une revue hal-04271860 v1
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Heart rate reduction after genetic ablation of L-type Cav1.3 channels induces cardioprotection against ischemia-reperfusion injury

Viviana Delgado-Betancourt , Kroekkiat Chinda , Pietro Mesirca , Christian Barrère , Aurélie Covinhes et al.
Frontiers in Cardiovascular Medicine, 2023, 10, pp.1134503. ⟨10.3389/fcvm.2023.1134503⟩
Article dans une revue hal-04184437 v1
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Characterization of sinoatrial automaticity in Microcebus murinus to study the effect of aging on cardiac activity and the correlation with longevity

Mattia Difrancesco , Manon Marrot , Eleonora Torre , Pietro Mesirca , Romain Davaze et al.
Scientific Reports, 2023, 13 (1), pp.3054. ⟨10.1038/s41598-023-29723-5⟩
Article dans une revue hal-04010411 v1
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L-Type Cav1.3 Calcium Channels Are Required for Beta-Adrenergic Triggered Automaticity in Dormant Mouse Sinoatrial Pacemaker Cells

Julien Louradour , Olivier Bortolotti , Eleonora Torre , Isabelle Bidaud , Ned Lamb et al.
Cells, 2022, 11 (7), pp.1114. ⟨10.3390/cells11071114⟩
Article dans une revue hal-03628407 v1
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Genetic Ablation of G Protein-Gated Inwardly Rectifying K+ Channels Prevents Training-Induced Sinus Bradycardia

Isabelle Bidaud , Alicia D’souza , Gabriella Forte , Eleonora Torre , Denis Greuet et al.
Frontiers in Physiology, 2021, 11, pp.519382. ⟨10.3389/fphys.2020.519382⟩
Article dans une revue hal-03437526 v1
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Electrophysiological and Molecular Mechanisms of Sinoatrial Node Mechanosensitivity

Daniel Turner , Chen Kang , Pietro Mesirca , Juan Hong , Matteo E. Mangoni et al.
Frontiers in Cardiovascular Medicine, 2021, 8, pp.662410. ⟨10.3389/fcvm.2021.662410⟩
Article dans une revue hal-03437522 v1
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The funny current in genetically modified mice

Mattia Difrancesco , Pietro Mesirca , Isabelle Bidaud , Dirk Isbrandt , Matteo Mangoni
Progress in Biophysics and Molecular Biology, 2021, 166, pp.39-50. ⟨10.1016/j.pbiomolbio.2021.06.003⟩
Article dans une revue hal-03437498 v1
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Pharmacologic Approach to Sinoatrial Node Dysfunction

Pietro Mesirca , Vadim Fedorov , Thomas Hund , Angelo Torrente , Isabelle Bidaud et al.
Annual Review of Pharmacology and Toxicology, 2021, 61, pp.757-778. ⟨10.1146/annurev-pharmtox-031120-115815⟩
Article dans une revue hal-02960337 v1
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Regulation of sinus node pacemaking and atrioventricular node conduction by HCN channels in health and disease

Mark Boyett , Joseph Yanni , James Tellez , Annalisa Bucchi , Pietro Mesirca et al.
Progress in Biophysics and Molecular Biology, 2021, 166, pp.61-85. ⟨10.1016/j.pbiomolbio.2021.06.008⟩
Article dans une revue hal-03437472 v1
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Genetic Complexity of Sinoatrial Node Dysfunction

Michael Wallace , Mona El Refaey , Pietro Mesirca , Thomas J Hund , Matteo Mangoni et al.
Frontiers in Genetics, 2021, 12, pp.654925. ⟨10.3389/fgene.2021.654925⟩
Article dans une revue (article de synthèse) hal-03437525 v1
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ESC working group on cardiac cellular electrophysiology position paper: relevance, opportunities, and limitations of experimental models for cardiac electrophysiology research

Katja Odening , Ana Maria Gómez , Dobromir Dobrev , Larissa Fabritz , Frank Heinzel et al.
EP-Europace, 2021, 23 (11), pp.1795-1814. ⟨10.1093/europace/euab142⟩
Article dans une revue hal-03437471 v1

The funny current in genetically modified mice

Mattia Difrancesco , Pietro Mesirca , Isabelle Bidaud , Dirk Isbrandt , Matteo E. Mangoni
Progress in Biophysics and Molecular Biology, 2021, 166, pp.39-50. ⟨10.1016/j.pbiomolbio.2021.06.003⟩
Article dans une revue hal-03263876 v1
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Intrinsic Electrical Remodeling Underlies Atrioventricular Block in Athletes

Pietro Mesirca , Shu Nakao , Sarah Dalgas Nissen , Gabriella Forte , Cali Anderson et al.
Circulation Research, 2021, 129 (1), pp.e1-e20. ⟨10.1161/CIRCRESAHA.119.316386⟩
Article dans une revue hal-03437523 v1
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A circadian clock in the sinus node mediates day-night rhythms in Hcn4 and heart rate

Alicia D’souza , Yanwen Wang , Cali Anderson , Annalisa Bucchi , Mirko Baruscotti et al.
Heart Rhythm, 2021, 18 (5), pp.801-810. ⟨10.1016/j.hrthm.2020.11.026⟩
Article dans une revue hal-03437524 v1
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Inhibition of G protein-gated K+ channels by tertiapin-Q rescues sinus node dysfunction and atrioventricular conduction in mouse models of primary bradycardia

Isabelle Bidaud , Antony Chung You Chong , Agnès Carcouët , Stephan De Waard , Flavien Charpentier et al.
Scientific Reports, 2020, 10 (1), pp.9835. ⟨10.1038/s41598-020-66673-8⟩
Article dans une revue hal-02885001 v1
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Functional Impact of BeKm-1, a High-Affinity hERG Blocker, on Cardiomyocytes Derived from Human-Induced Pluripotent Stem Cells

Stephan de Waard , Jérôme Montnach , Barbara Ribeiro , Sébastien Nicolas , Virginie Forest et al.
International Journal of Molecular Sciences, 2020, 21 (19), pp.7167. ⟨10.3390/ijms21197167⟩
Article dans une revue hal-02951542 v1
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Maurocalcin and its analogue MCaE12A facilitate Ca2+ mobilization in cardiomyocytes

Stephan de Waard , Jérôme Montnach , Charly Cortinovis , Olfa Chkir , Morteza Erfanian et al.
Biochemical Journal, 2020, 477 (20), pp.3985-3999. ⟨10.1042/BCJ20200206⟩
Article dans une revue inserm-02968252 v1
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Channelopathies of voltage-gated L-type Cav1.3/α1D and T-type Cav3.1/α1G Ca2+ channels in dysfunction of heart automaticity

Angelo Torrente , Pietro Mesirca , Isabelle Bidaud , Matteo E. Mangoni
Pflügers Archiv European Journal of Physiology, 2020, 472 (7), pp.817 - 830. ⟨10.1007/s00424-020-02421-1⟩
Article dans une revue hal-02892374 v1
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Concomitant genetic ablation of L-type Cav1.3 (α1D) and T-type Cav3.1 (α1G) Ca2+ channels disrupts heart automaticity

Matthias Baudot , Eleonora Torre , Isabelle Bidaud , Julien Louradour , Angelo G Torrente et al.
Scientific Reports, 2020, 10 (1), pp.18906. ⟨10.1038/s41598-020-76049-7⟩
Article dans une revue hal-03013849 v1

Mitochondria and L-Type Ca2+ channels interplay in the regulation of Ca2+ dynamics in murine pacemaker cells

L. Fossier , Angelo Torrente , J. Louradour , I. Bidaud , Matteo E. Mangoni et al.
Archives of Cardiovascular Diseases Supplements, 2019, 11 (2), pp.266-267. ⟨10.1016/j.acvdsp.2019.02.180⟩
Article dans une revue hal-04723899 v1
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Génération de la fonction sinusale et perspectives thérapeutiques

Pietro Mesirca , A.-G. Torrente , Isabelle Bidaud , M. Baudot , Joël Nargeot et al.
Archives des Maladies du Coeur et des Vaisseaux - Pratique, 2018, 2018 (267), pp.35 - 39. ⟨10.1016/j.amcp.2018.02.007⟩
Article dans une revue hal-02440724 v1
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A synthetic peptide that prevents cAMP regulation in mammalian hyperpolarization-activated cyclic nucleotide-gated (HCN) channels

A. Saponaro , F. Cantini , A. Porro , A. Bucchi , D. Difrancesco et al.
Article dans une revue hal-02073210 v1
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Clock-dependent and system-driven oscillators interact in the suprachiasmatic nuclei to pace mammalian circadian rhythms

Karine Abitbol , Segolene Debiesse , François Molino , Pietro Mesirca , Isabelle Bidaud et al.
PLoS ONE, 2017, 12 (10), pp.e0187001. ⟨10.1371/journal.pone.0187001⟩
Article dans une revue hal-01724552 v1
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CaV1.3 L-type Ca2+ channel contributes to the heartbeat by generating a dihydropyridine-sensitive persistent Na+ current

Futoshi Toyoda , Pietro Mesirca , Stefan Dübel , Wei-Guang Ding , Joerg Striessnig et al.
Scientific Reports, 2017, 7 (1), pp.7869. ⟨10.1038/s41598-017-08191-8⟩
Article dans une revue hal-01778161 v1
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Comment on: 'Homozygous knockout of the piezo1 gene in the zebrafish is not associated with anemia

Adèle Faucherre , K. Kissa , Joël Nargeot , Matteo E. Mangoni , Chris Jopling
Haematologica, 2016, 101 (1), pp.e38. ⟨10.3324/haematol.2015.137398⟩
Article dans une revue hal-01940741 v1
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G protein-gated IKACh channels as therapeutic targets for treatment of sick sinus syndrome and heart block

Pietro Mesirca , Isabelle Bidaud , François Briec , Stéphane Evain , Angelo G. Torrente et al.
Proceedings of the National Academy of Sciences of the United States of America, 2016, 113 (7), pp.E932--941. ⟨10.1073/pnas.1517181113⟩
Article dans une revue hal-01831593 v1
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Desmosomes and sino-atrial dysfunction

Matteo E. Mangoni
Cardiovascular Research, 2016, 111 (3), pp.167--168. ⟨10.1093/cvr/cvw171⟩
Article dans une revue hal-01940738 v1
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Rescuing cardiac automaticity in L-type Cav1.3 channelopathies and beyond

Pietro Mesirca , Isabelle Bidaud , Matteo E. Mangoni
The Journal of Physiology, 2016, ⟨10.1113/JP270678⟩
Article dans une revue hal-01942452 v1
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L-type Ca v 1.3 channels regulate ryanodine receptor-dependent Ca 2+ release during sino-atrial node pacemaker activity

Angelo Torrente , Pietro Mesirca , Patricia Neco , Riccardo Rizzetto , Stefan Dübel et al.
Cardiovascular Research, 2016, 109 (3), pp.451-461. ⟨10.1093/cvr/cvw006⟩
Article dans une revue hal-01792471 v1
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Cardiac arrhythmia induced by genetic silencing of 'funny' (f) channels is rescued by GIRK4 inactivation

Pietro Mesirca , J. Alig , Angelo Torrente , J.C Muller , L. Marger et al.
Nature Communications, 2014, 5, pp.4664. ⟨10.1038/ncomms5664⟩
Article dans une revue hal-01059204 v1

Paradoxical Effect of Increased Diastolic Ca 2+ Release and Decreased Sinoatrial Node Activity in a Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia

Patricia Neco , Angelo Torrente , Pietro Mesirca , Esther Zorio , Nian Liu et al.
Circulation, 2012, 126 (4), pp.392-401. ⟨10.1161/CIRCULATIONAHA.111.075382⟩
Article dans une revue hal-02477214 v1

Identification of Potential Pharmacological Targets by Analysis of the Comprehensive G Protein-Coupled Receptor Repertoire in the Four Cardiac Chambers

Thomas Moore-Morris , Annie Varrault , Matteo E. Mangoni , Anne Le Digarcher , V. Negre et al.
Molecular Pharmacology, 2009, 75 (5), pp.1108 - 1116. ⟨10.1124/mol.108.054155⟩
Article dans une revue hal-01788903 v1

Voltage-dependent calcium channels and cardiac pacemaker activity: From ionic currents to genes

Matteo E. Mangoni , Brigitte Couette , L. Marger , Emmanuel Bourinet , J. Striessnig et al.
Progress in Biophysics and Molecular Biology, 2006, 90, pp.38-63. ⟨10.1016/j.pbiomolbio.2005.05.003⟩
Article dans une revue istex hal-00017071 v1

Specific pattern of ionic channel gene expression associated with pacemaker activity in the mouse heart

C. Marionneau , Brigitte Couette , J. Liu , H. Li , Matteo E. Mangoni et al.
The Journal of Physiology, 2005, 562, pp.223-234. ⟨10.1113/jphysiol.2004.074047⟩
Article dans une revue hal-00017075 v1

Cholinergic regulation of cardiac pacemaker activity by l-type cav1.3 channels

Leïla Talssi , Isabelle Bidaud , Pietro Mesirca , Matteo E. Mangoni
ESC Congress 2020 – The Digital Experience, European Society of Cardiology, Aug 2020, Virtuel - Online, Netherlands. pp.3597, ⟨10.1093/ehjci/ehaa946.3597⟩
Communication dans un congrès hal-04773146 v1

Functional role for the GIRK1/4, Cav1.3 and HCN4 channels in muscarinic regulation of heart rate

Leïla Talssi , Isabelle Bidaud , Matteo Elia Mangoni , Pietro Mesirca
86th Congress of French Physiological Society, Nouvelle Faculté de Médecine, Jun 2019, Montpellier, France. pp.46, ⟨10.1111/apha.13389⟩
Communication dans un congrès hal-04730581 v1

Calciseptine isolated from the black mamba toxin selectively blocks cardiac Cav1.2 (alpha1C) versus Cav1.3 (alpha1D) L-type calcium channels

Pietro Mesirca , Jean Chemin , Christian Barrere , Eleonora Torre , Laura Gallot et al.
38th Meeting of the European Section of International Society, Jun 2024, Toulouse, France
Poster de conférence hal-04789795 v1

L-type Cav1.3 channels as key effectors of heart rate acceleration by catecholamines

Melanie Faure , Eleonora Torre , Isabelle Bidaud , Marvin Gaillardon , Stéphanie Barrère-Lemaire et al.
38th Meeting of the European Section of International Society, Jun 2024, Toulouse, France
Poster de conférence hal-04789809 v1

Consequences of aging on the adaptative capacity of Microcebus murinus heart to stress

Manon Marrot , Yasmine Colombani , Joel Cuoq , Pascaline Fontes , Faustine Hugon et al.
38th Meeting of the European Section of International Society, Jun 2024, Toulouse, France
Poster de conférence hal-04789810 v1

Evidence for a selective blockade of Cav1.2 versus Cav1.3 by the mamba toxin calciseptine in the mouse heart

Stéphanie Barrère-Lemaire , Christian Barrère , K. Chinda , Pietro Mesirca , C. Aurélie et al.
ECongrès le Printemps de la Cardiologie, Oct 2020, grenoble, France. 12 (2-4), pp.259, 2020, ⟨10.1016/j.acvdsp.2020.03.144⟩
Poster de conférence hal-03429844 v1

Developing Synthetic Peptides to Regulate Native HCN Channels

Andrea Saponaro , Francesca Cantini , Alessandro Porro , Annalisa Bucchi , Dario Difrancesco et al.
Biophysical Society 63rd Annual Meeting, Mar 2019, Baltimore (MD), United States. Cell Press, Biophysical Journal, 116 (3 suppl. 1), pp.302a, 2019
Poster de conférence hal-04777201 v1