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33

mes publications


thematique de recherche


Journal articles30 documents

  • Julien Louradour, Olivier Bortolotti, Eleonora Torre, Isabelle Bidaud, Ned Lamb, et al.. L-Type Cav1.3 Calcium Channels Are Required for Beta-Adrenergic Triggered Automaticity in Dormant Mouse Sinoatrial Pacemaker Cells. Cells, 2022, 11 (7), pp.1114. ⟨10.3390/cells11071114⟩. ⟨hal-03628407⟩
  • Pietro Mesirca, Vadim Fedorov, Thomas Hund, Angelo Torrente, Isabelle Bidaud, et al.. Pharmacologic Approach to Sinoatrial Node Dysfunction. Annual Review of Pharmacology and Toxicology, 2021, 61, pp.757-778. ⟨10.1146/annurev-pharmtox-031120-115815⟩. ⟨hal-02960337⟩
  • Mattia Difrancesco, Pietro Mesirca, Isabelle Bidaud, Dirk Isbrandt, Matteo E. Mangoni. The funny current in genetically modified mice. Progress in Biophysics and Molecular Biology, 2021, ⟨10.1016/j.pbiomolbio.2021.06.003⟩. ⟨hal-03263876⟩
  • Pietro Mesirca, Shu Nakao, Sarah Dalgas Nissen, Gabriella Forte, Cali Anderson, et al.. Intrinsic Electrical Remodeling Underlies Atrioventricular Block in Athletes. Circulation Research, 2021, 129 (1), pp.e1-e20. ⟨10.1161/CIRCRESAHA.119.316386⟩. ⟨hal-03437523⟩
  • Isabelle Bidaud, Alicia D’souza, Gabriella Forte, Eleonora Torre, Denis Greuet, et al.. Genetic Ablation of G Protein-Gated Inwardly Rectifying K+ Channels Prevents Training-Induced Sinus Bradycardia. Frontiers in Physiology, 2021, 11, ⟨10.3389/fphys.2020.519382⟩. ⟨hal-03437526⟩
  • Mattia Difrancesco, Pietro Mesirca, Isabelle Bidaud, Dirk Isbrandt, Matteo Mangoni. The funny current in genetically modified mice. Progress in Biophysics and Molecular Biology, 2021, 166, pp.39-50. ⟨10.1016/j.pbiomolbio.2021.06.003⟩. ⟨hal-03437498⟩
  • Daniel Turner, Chen Kang, Pietro Mesirca, Juan Hong, Matteo E. Mangoni, et al.. Electrophysiological and Molecular Mechanisms of Sinoatrial Node Mechanosensitivity. Frontiers in Cardiovascular Medicine, 2021, 8, ⟨10.3389/fcvm.2021.662410⟩. ⟨hal-03437522⟩
  • Katja Odening, Ana-Maria Gomez, Dobromir Dobrev, Larissa Fabritz, Frank Heinzel, et al.. ESC working group on cardiac cellular electrophysiology position paper: relevance, opportunities, and limitations of experimental models for cardiac electrophysiology research. EP-Europace, 2021, 23 (11), pp.1795-1814. ⟨10.1093/europace/euab142⟩. ⟨hal-03437471⟩
  • Michael Wallace, Mona El Refaey, Pietro Mesirca, Thomas Hund, Matteo Mangoni, et al.. Genetic Complexity of Sinoatrial Node Dysfunction. Frontiers in Genetics, 2021, 12, ⟨10.3389/fgene.2021.654925⟩. ⟨hal-03437525⟩
  • Alicia D’souza, Yanwen Wang, Cali Anderson, Annalisa Bucchi, Mirko Baruscotti, et al.. A circadian clock in the sinus node mediates day-night rhythms in Hcn4 and heart rate. Heart Rhythm, 2021, 18 (5), pp.801-810. ⟨10.1016/j.hrthm.2020.11.026⟩. ⟨hal-03437524⟩
  • Mark Boyett, Joseph Yanni, James Tellez, Annalisa Bucchi, Pietro Mesirca, et al.. Regulation of sinus node pacemaking and atrioventricular node conduction by HCN channels in health and disease. Progress in Biophysics and Molecular Biology, 2021, 166, pp.61-85. ⟨10.1016/j.pbiomolbio.2021.06.008⟩. ⟨hal-03437472⟩
  • Stephan de Waard, Jérome Montnach, Charly Cortinovis, Olfa Chkir, Morteza Erfanian, et al.. Maurocalcin and its analogue MCaE12A facilitate Ca2+ mobilization in cardiomyocytes. Biochemical Journal, 2020, Online ahead of print. ⟨10.1042/BCJ20200206⟩. ⟨inserm-02968252⟩
  • Isabelle Bidaud, Antony Chung You Chong, Agnès Carcouët, Stephan De Waard, Flavien Charpentier, et al.. Inhibition of G protein-gated K+ channels by tertiapin-Q rescues sinus node dysfunction and atrioventricular conduction in mouse models of primary bradycardia. Scientific Reports, 2020, 10 (1), ⟨10.1038/s41598-020-66673-8⟩. ⟨hal-02885001⟩
  • Stephan de Waard, Jérôme Montnach, Barbara Ribeiro, Sébastien Nicolas, Virginie Forest, et al.. Functional Impact of BeKm-1, a High-Affinity hERG Blocker, on Cardiomyocytes Derived from Human-Induced Pluripotent Stem Cells. International Journal of Molecular Sciences, 2020, 2020, ⟨10.3390/ijms21197167⟩. ⟨hal-02951542⟩
  • Matthias Baudot, Eleonora Torre, Isabelle Bidaud, Julien Louradour, Angelo G Torrente, et al.. Concomitant genetic ablation of L-type Cav1.3 (α1D) and T-type Cav3.1 (α1G) Ca2+ channels disrupts heart automaticity. Scientific Reports, 2020, 10 (1), ⟨10.1038/s41598-020-76049-7⟩. ⟨hal-03013849⟩
  • Angelo Torrente, Pietro Mesirca, Isabelle Bidaud, Matteo E. Mangoni. Channelopathies of voltage-gated L-type Cav1.3/α1D and T-type Cav3.1/α1G Ca2+ channels in dysfunction of heart automaticity. Pflügers Archiv European Journal of Physiology, 2020, 472 (7), pp.817 - 830. ⟨10.1007/s00424-020-02421-1⟩. ⟨hal-02892374⟩
  • Pietro Mesirca, A.-G. Torrente, Isabelle Bidaud, M. Baudot, Joël Nargeot, et al.. Génération de la fonction sinusale et perspectives thérapeutiques. Archives des Maladies du Coeur et des Vaisseaux - Pratique, 2018, 2018 (267), pp.35 - 39. ⟨10.1016/j.amcp.2018.02.007⟩. ⟨hal-02440724⟩
  • A. Saponaro, F. Cantini, A. Porro, A. Bucchi, D. Difrancesco, et al.. A synthetic peptide that prevents cAMP regulation in mammalian hyperpolarization-activated cyclic nucleotide-gated (HCN) channels. eLife, 2018, 7, ⟨10.7554/eLife.35753⟩. ⟨hal-02073210⟩
  • Futoshi Toyoda, Pietro Mesirca, Stefan Dübel, Wei-Guang Ding, Joerg Striessnig, et al.. CaV1.3 L-type Ca2+ channel contributes to the heartbeat by generating a dihydropyridine-sensitive persistent Na+ current. Scientific Reports, 2017, 7 (1), pp.7869. ⟨10.1038/s41598-017-08191-8⟩. ⟨hal-01778161⟩
  • Karine Abitbol, Segolene Debiesse, François Molino, Pietro Mesirca, Isabelle Bidaud, et al.. Clock-dependent and system-driven oscillators interact in the suprachiasmatic nuclei to pace mammalian circadian rhythms. PLoS ONE, 2017, 12 (10), pp.e0187001. ⟨10.1371/journal.pone.0187001⟩. ⟨hal-01724552⟩
  • Pietro Mesirca, Isabelle Bidaud, Matteo E. Mangoni. Rescuing cardiac automaticity in L-type Cav1.3 channelopathies and beyond. The Journal of Physiology, 2016, ⟨10.1113/JP270678⟩. ⟨hal-01942452⟩
  • Matteo E. Mangoni. Desmosomes and sino-atrial dysfunction. Cardiovascular Research, 2016, 111 (3), pp.167--168. ⟨10.1093/cvr/cvw171⟩. ⟨hal-01940738⟩
  • Pietro Mesirca, Isabelle Bidaud, François Briec, Stéphane Evain, Angelo G. Torrente, et al.. G protein-gated IKACh channels as therapeutic targets for treatment of sick sinus syndrome and heart block. Proceedings of the National Academy of Sciences of the United States of America, 2016, 113 (7), pp.E932--941. ⟨10.1073/pnas.1517181113⟩. ⟨hal-01831593⟩
  • Angelo Torrente, Pietro Mesirca, Patricia Neco, Riccardo Rizzetto, Stefan Dübel, et al.. L-type Ca v 1.3 channels regulate ryanodine receptor-dependent Ca 2+ release during sino-atrial node pacemaker activity. Cardiovascular Research, 2016, 109 (3), pp.451-461. ⟨10.1093/cvr/cvw006⟩. ⟨hal-01792471⟩
  • Adèle Faucherre, K. Kissa, Joël Nargeot, Matteo E. Mangoni, Chris Jopling. Comment on: 'Homozygous knockout of the piezo1 gene in the zebrafish is not associated with anemia'. Haematologica, 2016, 101 (1), pp.e38. ⟨10.3324/haematol.2015.137398⟩. ⟨hal-01940741⟩
  • Pietro Mesirca, J. Alig, Angelo Torrente, J.C Muller, L. Marger, et al.. Cardiac arrhythmia induced by genetic silencing of 'funny' (f) channels is rescued by GIRK4 inactivation. Nature Communications, 2014, 5, pp.4664. ⟨10.1038/ncomms5664⟩. ⟨hal-01059204⟩
  • Patricia Neco, Angelo Torrente, Pietro Mesirca, Esther Zorio, Nian Liu, et al.. Paradoxical Effect of Increased Diastolic Ca 2+ Release and Decreased Sinoatrial Node Activity in a Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia: Depressed SAN Automaticity in CPVT. Circulation, 2012, 126 (4), pp.392-401. ⟨10.1161/CIRCULATIONAHA.111.075382⟩. ⟨hal-02477214⟩
  • Thomas Moore-Morris, Annie Varrault, Matteo E. Mangoni, Anne Le Digarcher, V. Negre, et al.. Identification of Potential Pharmacological Targets by Analysis of the Comprehensive G Protein-Coupled Receptor Repertoire in the Four Cardiac Chambers. Molecular Pharmacology, 2009, 75 (5), pp.1108 - 1116. ⟨10.1124/mol.108.054155⟩. ⟨hal-01788903⟩
  • Matteo E. Mangoni, Brigitte Couette, L. Marger, Emmanuel Bourinet, J. Striessnig, et al.. Voltage-dependent calcium channels and cardiac pacemaker activity: From ionic currents to genes. Progress in Biophysics and Molecular Biology, 2006, 90, pp.38-63. ⟨10.1016/j.pbiomolbio.2005.05.003⟩. ⟨hal-00017071⟩
  • C. Marionneau, Brigitte Couette, J. Liu, H. Li, Matteo E. Mangoni, et al.. Specific pattern of ionic channel gene expression associated with pacemaker activity in the mouse heart. The Journal of Physiology, 2005, 562, pp.223-234. ⟨10.1113/jphysiol.2004.074047⟩. ⟨hal-00017075⟩

Conference poster1 document

  • Stéphanie Barrère-Lemaire, Christian Barrère, K. Chinda, Pietro Mesirca, C. Aurélie, et al.. Evidence for a selective blockade of Cav1.2 versus Cav1.3 by the mamba toxin calciseptine in the mouse heart. ECongrès le Printemps de la Cardiologie, Oct 2020, grenoble, France. 12 (2-4), pp.259, 2020, ⟨10.1016/j.acvdsp.2020.03.144⟩. ⟨hal-03429844⟩

Preprints, Working Papers, ...2 documents

  • Mattia Difrancesco, Romain Davaze, Eleonora Torre, Pietro Mesirca, Manon Marrot, et al.. Characterization of cardiac pacemaker activity in the primate lemur Microcebus murinus. 2021. ⟨hal-03441011⟩
  • Pietro Mesirca, Daria Mamaeva, Isabelle Bidaud, Romain Davaze, Mattia L Difrancesco, et al.. Bradycardic mice undergo effective heart rate improvement after specific homing to the sino-atrial node and differentiation of adult muscle derived stem cells. 2018. ⟨hal-02394274⟩