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Presentation
Je suis maître de conférences à l'Université Paris-Est Créteil et chercheur au laboratoire MSME. Mon parcours académique se situe dans le domaine du Génie Mécanique et des Matériaux, et je me suis spécialisé en Biomécanique et en Physique Statistique au cours de mes études de Master et de doctorat.
Mon domaine de recherche principal concerne la modélisation des processus biomécaniques moléculaires coopératifs, avec un accent particulier sur la contraction musculaire. Dans mon travail, je vise à intégrer des connaissances provenant de divers domaines, de la physiologie aux mathématiques appliquées, afin d'explorer les dimensions multiphysique des phénomènes biomécaniques.
J'enseigne par ailleur le génie mécanique à l'Université Paris-Est Créteil et également à l'École Polytechnique dans le cadre d'un un cours de physique statistique appliquée à la motilité cellulaire. Je forme également les étudiants en doctorat aux outils d'écriture et de publication académique tels que LaTeX et Pandoc.
Au fil des années, j'ai eu l'opportunité de développer diverses collaboration scientifiques. J'ai travaillé avec l'équipe Inria MΞDISIM sur des méthodes mathématiques et numériques pour la modélisation biomécanique computationnelle. Certaines de mes collaborations notables incluent Anne Houdusse de l'Institut Curie à Paris, J.E. Rothman de l'université Yale et Prix Nobel de Physiologie/Médecice (2013), et enfin l'équipe PhysioLab dirigée par V. Lombardi et M. Linari, spécialisée en physiologie musculaire expérimentale.
Je suis engagé pour la stimulation des efforts collaboratifs interdisciplinaire dans le domaine de la biomécanique.
I am an associate professor at the University of Paris-Est Créteil and a researcher at the MSME laboratory. My academic background is in Mechanical Engineering and Materials, and I specialized in Biomechanics and Statistical Physics during my Master's and Ph.D. studies.
My primary research area focuses on modeling cooperative molecular biomechanical processes, with a particular emphasis on muscle contraction. In my work, I aim to integrate knowledge from various fields, ranging from physiology to applied mathematics, to explore the multi-physics dimensions of biomechanical phenomena.
I also teach mechanical engineering at the University of Paris-Est Créteil and at the École Polytechnique as part of a course in applied statistical physics for cell motility. Additionally, I provide training to doctoral students in academic writing and publishing tools such as LaTeX and Pandoc.
Over the years, I have had the opportunity to establish various scientific collaborations. I have worked with the Inria MΞDISIM team on mathematical and numerical methods for computational biomechanical modeling. Some of my notable collaborations include Anne Houdusse from the Institut Curie in Paris, J.E. Rothman from Yale University, who received the Nobel Prize in Physiology/Medicine (2013), and the PhysioLab team led by V. Lombardi and M. Linari, specializing in experimental muscle physiology.
I am committed to fostering interdisciplinary collaborative efforts in the field of biomechanics.
Research domains
Solid mechanics [physics.class-ph]
Publications
Synergistic interplay between mechanics and chemistry in architected molecular motors assemblies57th Meeting of the Society for Natural Philosophy, Complex Material Structures, Natural and Architected, Oct 2023, PARIS, France
Conference papers
hal-04265698v1
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Étude mécanique d'une protéine du muscleJournée thématique Biomécanque et Biomatériaux, Apr 2021, Paris, France
Conference papers
hal-03675502v1
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Intrinsic regulation of muscle contractionVPH 2020 - Virtual Physiological Human, Aug 2020, Paris, France
Conference papers
hal-03156494v1
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Activation-contraction coupling in a multiscale heart modelCMBE 2019 - 6th International Conference on Computational and Mathematical Biomedical Engineering, Jun 2019, Sendai, Japan
Conference papers
hal-02493552v1
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Mechanical Modeling of Active and Passive Force Generation in Skeletal MusclesNonconvexity, Nonlocality and Incompatibility: From Materials to Biology Conference in honor of Lev Truskinovsky’s 60th birthday, May 2017, Pittsburgh, United States
Conference papers
hal-01802127v1
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Buckling response of architectured columns: controlling instability across the scales through a rational design.13e colloque national en calcul des structures, Université Paris-Saclay, May 2017, Giens, Var, France
Conference papers
hal-01899349v1
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Thermodynamical framework for modeling chemo-mechanical coupling in muscle contraction – Formulation and preliminary results22e congrès Français de Mécanique, Aug 2015, Lyon, France
Conference papers
hal-01802124v1
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HUXLEY-SIMMONS MODEL REVISITED4th International Conference on Computational and Mathematical Biomedical Engineering - CMBE2015, Jun 2015, Paris, France
Conference papers
hal-01180003v1
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Activities of the Biomechanics Group of the MSME laboratorySymposium franco – germano – polonais sur les biomatériaux architecturés pour la médecine, Dec 2014, Berlin, Germany
Conference papers
hal-01167292v1
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Dimensional Reduction of Cardiac Models for Effective Validation and Calibration7th International Conference on Functional Imaging and Modeling of the Heart, FIMH 2013, Jun 2013, London, United Kingdom. pp.259-267
Conference papers
hal-00834704v1
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Estimation of the free energy barrier of the step of P i release in myosin VI cycleESB 2022 Congress, Jun 2022, Porto, Portugal
Conference poster
hal-03727769v1
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Identification of free energy barriers associated with transition in Myosin cycle using Umbrella SamplingWorkshop Les Houches Protein Dynamics, May 2021, Les Houches, France
Conference poster
hal-03675520v1
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Cooperative folding of muscle myosins: I. Mechanical model2013
Preprints, Working Papers, ...
hal-00912457v1
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Mechanical modelling of muscle contraction[0] MSME, Université Paris-Est Marne La Vallée. 2018
Reports
hal-02776568v1
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Mechanics of Fast Force Recovery in striated musclesSolid mechanics [physics.class-ph]. Ecole Polytechnique X, 2011. English. ⟨NNT : ⟩
Theses
pastel-00668301v1
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