Mélanie Etheve

Publications

Article dans une revue (62)

Engineering Bisubstrates to Target m 6 Am RNA Methyltransferases: Synthesis and Computational Studies Yoann Colas,Laurent Le Corre,Mélanie Ethève-Quelquejeu,Emmanuelle Braud Chemistry - A European Journal, 2026, ⟨10.1002/chem.202503378⟩ Article dans une revue hal-05590494v1
A β‐Glucuronidase‐Responsive Albumin‐Binding Prodrug of a Potent Focal Adhesion Kinase Inhibitor for Targeted Cancer Therapy Louna Mossino,Rémi Châtre,Mélanie Poinsot,Mathieu Rodero,Pierre Niocheet al. ChemMedChem, 2025, 21 (4), pp.e202500746. ⟨10.1002/cmdc.202500746⟩ Article dans une revue hal-05468185v1
Synthesis of RNA conjugates as bisubstrates for the study of transferases Laura Iannazzo,Emmanuelle Braud,Matthieu Fonvielle,Mélanie Etheve-Quelquejeu Comptes Rendus. Chimie, 2025, 28 (G1), pp.111-129. ⟨10.5802/crchim.356⟩ Article dans une revue hal-05287289v1
Optimization of prodrug activation by enzymatic cleavage of the β‐lactam ring of carbapenems Katie Burke,Quentin Herail,Ines Zerguine,Catherine Bougault,Michel Arthuret al. Chemistry - A European Journal, 2025, 31 (46), pp.e01534. ⟨10.1002/chem.202501534⟩ Article dans une revue hal-05287283v1
Park7 (DJ-1), a Parkinson-associated glyoxalase/deglycase: characterization of enzymatic activity in biological samples using fluorescence-based liquid chromatography Nicolas Mathas,Emmanuelle Braud,Erwan Galardon,Lucie Larigot,Mélanie Etheve-Quelquejeuet al. Biochimie, 2025, 235, pp.113-121. ⟨10.1016/j.biochi.2025.06.005⟩ Article dans une revue hal-05343900v1
Metal‐Catalyzed Cross‐Coupling for the Synthesis of β‐Lactam Drugs and Related Chemical Probes Jules Bresson,Katie Burke,Mélanie Ethève‐quelquejeu,Laura Iannazzo,Kevin Cariou ChemMedChem, 2025, 20 (9), pp.e202400960. ⟨10.1002/cmdc.202400960⟩ Article dans une revue hal-05287299v1
Flexizyme‐Based Strategy for the Synthesis of Stable, Non‐Isomerizable Amide‐Linked 2’‐Aminoacyl‐tRNAs and their Shortened Analogs Lia Maurin,Carine Tellier-Lebegue,Laura Iannazzo,Takayuki Katoh,Delphine Patinet al. Chemistry - A European Journal, 2025, 63 (21), pp.12707-12724. ⟨10.1002/chem.202503506⟩ Article dans une revue hal-05468180v1
A multiscale study to characterize SHAPE probe/ RNA molecules pre-reactive complex and its role in initiating the SHAPE reaction Cécilia Hognon,Ameni Ben Abdeljaoued,Pierre Hardouin,Mélanie Etheve-Quelquejeu,Bruno Sargueilet al. Journal of Chemical Information and Modeling, 2025, ⟨10.1021/acs.jcim.5c00812⟩ Article dans une revue hal-05226372v1
Investigation of a squaramide motif as a bioisostere of the amino-acid group of S-adenosyl-L-methionine and its functional impact on RNA methylation Jianxun Du,Batoul Mahcene,Valerii Martynov,Elisa Frezza,Christelle Vasnieret al. Communications Chemistry, 2025, 8 (1), pp.244. ⟨10.1038/s42004-025-01627-7⟩ Article dans une revue hal-05287286v2
Synthetic approaches to bis-adenosine derivatives as potential bisubstrates of RNA methyltransferases Jianxun Du,Bastien Felipe,Dylan Coelho,Laura Iannazzo,Alexandre Davidet al. Organic & Biomolecular Chemistry, 2025, 23 (24), pp.5887-5896. ⟨10.1039/D5OB00758E⟩ Article dans une revue hal-05139585v1
Copper catalyzed cycloaddition for the synthesis of non isomerisable 2’ and 3’-regioisomers of arg-tRNAarg Yusif Afandizada,Thilini Abeywansha,Vincent Guerineau,Yi Zhang,Bruno Sargueilet al. Methods, 2024, 229, pp.94-107. ⟨10.1016/j.ymeth.2024.05.017⟩ Article dans une revue hal-05312525v1
Halo‐1,2,3‐triazoles: Valuable Compounds to Access Biologically Relevant Molecules Dylan Coelho,Yoann Colas,Mélanie Ethève-Quelquejeu,Emmanuelle Braud,Laura Iannazzo ChemBioChem, 2024, 25 (10), pp.e202400150. ⟨10.1002/cbic.202400150⟩ Article dans une revue hal-05312524v1
Synthesis of Peptidyl-tRNA Mimics for Structural Biology Applications Yury Polikanov,Mélanie Ethève-Quelquejeu,Ronald Micura Accounts of Chemical Research, 2023, 56 (19), pp.2713-2725. ⟨10.1021/acs.accounts.3c00412⟩ Article dans une revue hal-05312531v1
The catalytic mechanism of the RNA methyltransferase METTL3 Ivan Corbeski,Pablo Andrés Vargas-Rosales,Rajiv Kumar Bedi,Jiahua Deng,Dylan Coelhoet al. eLife, 2023, ⟨10.7554/eLife.92537.1⟩ Article dans une revue hal-05287291v1
Synthesis of Bisubstrate Analogues for RNA Methylation Studies using two Transition‐Metal‐Catalyzed Reactions Dylan Coelho,Laurent Le Corre,Karolina Bartosik,Laura Iannazzo,Emmanuelle Braudet al. Chemistry - A European Journal, 2023, 29 (44), ⟨10.1002/chem.202301134⟩ Article dans une revue hal-04246592v1
PSL Chemical Biology Symposia Third Edition: A Branch of Science in its Explosive Phase Leeroy Baron,Justine Hadjerci,Leishemba Thoidingjam,Marina Plays,Romain Bucciet al. ChemBioChem, 2023, 24 (8), pp.e202300093. ⟨10.1002/cbic.202300093⟩ Article dans une revue hal-04092530v1
Ruthenium‐Catalyzed Cycloaddition for Introducing Chemical Diversity in Second‐Generation β‐Lactamase Inhibitors Flavie Bouchet,Jean‐philippe Barnier,Ines Sayah,Youcef Bagdad,Maria Mitevaet al. ChemMedChem, 2023, 18 (9), ⟨10.1002/cmdc.202300077⟩ Article dans une revue hal-05312533v1
Traceless Staudinger Ligation to Access Stable Aminoacyl- or Peptidyl-Dinucleotide Camélia Kitoun,Saidbakhrom Saidjalolov,Delphine Bouquet,Fabiola Djago,Quentin Blancart-Remauryet al. ACS Omega, 2023, 8 (4), pp.3850-3860. ⟨10.1021/acsomega.2c06135⟩ Article dans une revue hal-04294940v1
Enzymatic synthesis of vancomycin-modified DNA Chiara Figazzolo,Frédéric Bonhomme,Saidbakhrom Saidjalolov,Mélanie Ethève-Quelquejeu,Marcel Hollenstein Molecules, 2022, 27 (24), pp.8927. ⟨10.3390/molecules27248927⟩ Article dans une revue hal-03927068v1
Amino-acyl tXNA as inhibitors or amino acid donors in peptide synthesis Lauriane Rietmeyer,Inès Li de la Sierra-Gallay,Guy Schepers,Delphine Dorchêne,Laura Iannazzoet al. Nucleic Acids Research, 2022, ⟨10.1093/nar/gkac1023⟩ Article dans une revue hal-03879768v1
Modulation of the Specificity of Carbapenems and Diazabicyclooctanes for Selective Activity against Mycobacterium tuberculosis Jean-Philippe Barnier,Saidbakhrom Saidjalolov,Flavie Bouchet,Louis Mayer,Zainab Edooet al. Antimicrobial Agents and Chemotherapy, 2022, 66 (9), ⟨10.1128/aac.02357-21⟩ Article dans une revue hal-05312535v1
Synthesis of RNA-cofactor conjugates and structural exploration of RNA recognition by an m6A RNA methyltransferase Vincent Meynier,Laura Iannazzo,Marjorie Catala,Stephanie Oerum,Emmanuelle Braudet al. Nucleic Acids Research, 2022, ⟨10.1093/nar/gkac354⟩ Article dans une revue hal-03689976v1
Click and Release Chemistry for Activity-Based Purification of β-Lactam Targets Saidbakhrom Saidjalolov,Emmanuelle Braud,Zainab Edoo,Laura Iannazzo,Filippo Rusconiet al. Chemistry - A European Journal, 2021, 27 (28), pp.7687-7695. ⟨10.1002/chem.202100653⟩ Article dans une revue hal-03281379v1
Traceless Staudinger Ligation To Introduce Chemical Diversity on β-Lactamase Inhibitors of Second Generation Flavie Bouchet,Heiner Atze,Michel Arthur,Mélanie Ethève-Quelquejeu,Laura Iannazzo Organic Letters, 2021, 23 (20), pp.7755-7758. ⟨10.1021/acs.orglett.1c02741⟩ Article dans une revue hal-03647098v1
Synthesis of carbapenems containing peptidoglycanmimetics and inhibition of the cross-linking activity of a transpeptidase of the L,D specificity Saidbakhrom Saidjalolov,Zainab Edoo,Matthieu Fonvielle,Louis Mayer,Laura Iannazzoet al. Chemistry - A European Journal, 2021, 27 (10), pp.3542-3551. ⟨10.1002/chem.202004831⟩ Article dans une revue hal-03184204v1
Partition of tRNAGly isoacceptors between protein and cell-wall peptidoglycan synthesis in Staphylococcus aureus Lauriane Rietmeyer,Nicolas Fix-Boulier,Chloé Le Fournis,Laura Iannazzo,Camelia Kitounet al. Nucleic Acids Research, 2021, 49 (2), pp.684-699. ⟨10.1093/nar/gkaa1242⟩ Article dans une revue hal-03201622v1
Traceless Staudinger Ligation for Bioconjugation of RNA Camélia Kitoun,Matthieu Fonvielle,Michel Arthur,Mélanie Etheve‐quelquejeu,Laura Iannazzo Current Protocols, 2021, 1 (2), ⟨10.1002/cpz1.42⟩ Article dans une revue hal-03647120v1
Design, Synthesis, and Biological Evaluation of Covalent Inhibitors of Focal Adhesion Kinase (FAK) against Human Malignant Glioblastoma Bo Li,Yongliang Li,Céline Tomkiewicz-Raulet,Pascal Dao,Daniel Liethaet al. Journal of Medicinal Chemistry, 2020, 63 (21), pp.12707-12724. ⟨10.1021/acs.jmedchem.0c01059⟩ Article dans une revue hal-05437532v1
The neurobehavioral effects of the designer drug naphyrone – an experimental investigation with pharmacokinetics and concentration/effect relationship in mice Bruno Mégarbane,Camille Gamblin,Olivier Roussel,Elodie Bouaziz-Amar,Lucie Chevillardet al. Psychopharmacology, 2020, 237 (7), pp.1943-1957. ⟨10.1007/s00213-020-05510-2⟩ Article dans une revue hal-03823023v1
Phosphine-Mediated Bioconjugation of the 3′-End of RNA Camelia Kitoun,Matthieu Fonvielle,Nicolas Sakkas,Manon Lefresne,Fabiola Djagoet al. Organic Letters, 2020, 22 (20), pp.8034-8038. ⟨10.1021/acs.orglett.0c02982⟩ Article dans une revue hal-02996863v1
Diazabicyclooctane Functionalization for Inhibition of β-Lactamases from Enterobacteria Flavie Bouchet,Heiner Atze,Matthieu Fonvielle,Zainab Edoo,Michel Arthuret al. Journal of Medicinal Chemistry, 2020, 63 (10), pp.5257-5273. ⟨10.1021/acs.jmedchem.9b02125⟩ Article dans une revue hal-03646829v2
Microwave-assisted synthesis of 2,5-disubstituted pyrimidine derivatives via Buchwald-Hartwig amination Bo Li,Mélanie Etheve-Quelquejeu,Expédite Yen-Pon,Christiane Garbay,Huixiong Chen Tetrahedron Letters, 2020, 61, pp.151406 -. ⟨10.1016/j.tetlet.2019.151406⟩ Article dans une revue hal-03488531v1
Design and synthesis of a peptide derivative of ametantrone targeting the major groove of the d(GGCGCC) 2 palindromic sequence Alberto Ongaro,Giovanni Ribaudo,Emmanuelle Braud,Mélanie Ethève-Quelquejeu,Michele de Francoet al. New Journal of Chemistry, 2020, 44 (9), pp.3624-3631. ⟨10.1039/C9NJ03817E⟩ Article dans une revue hal-03689989v1
Raman reporters derived from aryl diazonium salts for SERS encoded-nanoparticles Yun Luo,Yu Xiao,Delphine Onidas,Laura Iannazzo,Mélanie Ethève-Quelquejeuet al. Chemical Communications, 2020, 56 (50), pp.6822-6825. ⟨10.1039/d0cc02842h⟩ Article dans une revue hal-03411993v1
Synthesis of triazole-linked SAM-adenosine 2 conjugates: functionalization of adenosine at N-1 or N-6 position without protecting groups Colette Atdjian,Dylan Coelho,Laura Iannazzo,Mélanie Etheve-Quelquejeu,Emmanuelle Braud Molecules, 2020, 25 (14), pp.3241. ⟨10.3390/molecules25143241⟩ Article dans une revue hal-02915430v1
Bisubstrate analogues as structural tools to investigate m 6 A methyltransferase active sites Stephanie Oerum,Marjorie Catala,Colette Atdjian,Franck Brachet,Luc Ponchonet al. RNA Biology, 2019, 16 (6), pp.798-808. ⟨10.1080/15476286.2019.1589360⟩ Article dans une revue hal-02353503v1
Acute and chronic neurobehavioral effects of the designer drug and bath salt constituent 3,4-methylenedioxypyrovalerone in the rat Luisa Alessandra Atehortua-Martinez,Cyriaque Masniere,Patrizia Campolongo,Stéphanie Chasseigneaux,Jacques Callebertet al. Journal of Psychopharmacology, 2019, 33 (3), pp.392-405. ⟨10.1177/0269881118822151⟩ Article dans une revue hal-03908457v1
Is the 3,4-methylendioxypyrovalerone/mephedrone combination responsible for enhanced stimulant effects? A rat study with investigation of the effect/concentration relationships Nadia Benturquia,Lucie Chevillard,Christophe Poiré,Olivier Roussel,Camille Cohieret al. Psychopharmacology, 2019, 236 (3), pp.891-901. ⟨10.1007/s00213-018-4962-0⟩ Article dans une revue hal-03823031v1
Negative impact of carbapenem methylation on the reactivity of β-lactams for cysteine acylation revealed by quantum calculations and kinetic analyses Nicholus Bhattacharjee,Sébastien Triboulet,Vincent Dubée,Matthieu Fonvielle,Zainab Edooet al. Antimicrobial Agents and Chemotherapy, 2019, 63 (4), pp.e02039-18. ⟨10.1128/AAC.02039-18⟩ Article dans une revue hal-02057268v1
Is the 3,4-methylendioxypyrovalerone/mephedrone combination responsible for enhanced stimulant effects? A rat study with investigation of the effect/concentration relationships Nadia Benturquia,Lucie Chevillard,Christophe Poiré,Olivier Roussel,Camille Cohieret al. Psychopharmacology, 2019, 236 (3), pp.891-901. ⟨10.1007/s00213-018-4962-0⟩ Article dans une revue hal-03860105v1
Acute and chronic neurobehavioral effects of the designer drug and bath salt constituent 3,4-methylenedioxypyrovalerone in the rat Luisa Alessandra Atehortua-Martinez,Cyriaque Masniere,Patrizia Campolongo,Stéphanie Chasseigneaux,Jacques Callebertet al. Journal of Psychopharmacology, 2019, 33 (3), pp.392-405. ⟨10.1177/0269881118822151⟩ Article dans une revue hal-02557840v1
Acute and chronic neurobehavioral effects of the designer drug and bath salt constituent 3,4-methylenedioxypyrovalerone in the rat Luisa Alessandra Atehortua-Martinez,Cyriaque Masniere,Patrizia Campolongo,Stéphanie Chasseigneaux,Jacques Callebertet al. Journal of Psychopharmacology, 2019, 33 (3), pp.392-405. ⟨10.1177/0269881118822151⟩ Article dans une revue hal-03860016v1
Synthesis of Avibactam Derivatives and Activity on β-Lactamases and Peptidoglycan Biosynthesis Enzymes of Mycobacteria Zainab Edoo,Laura Iannazzo,Fabrice Compain,Inès Li de La Sierra Gallay,Herman Van Tilbeurghet al. Chemistry - A European Journal, 2018, 24 (32), pp.8081--8086. ⟨10.1002/chem.201800923⟩ Article dans une revue hal-02177911v1
Structure-Based Design, Synthesis, and Characterization of the First Irreversible Inhibitor of Focal Adhesion Kinase Expédite Yen-Pon,Bo Li,Marta Acebrón-Garcia-De-Eulate,Céline Tomkiewicz-Raulet,John Dawsonet al. ACS Chemical Biology, 2018, 13 (8), pp.2067-2073. ⟨10.1021/acschembio.8b00250⟩ Article dans une revue hal-02196326v1
Synthesis of SAM-Adenosine Conjugates for the Study of m 6 A-RNA Methyltransferases Colette Atdjian,Laura Iannazzo,Emmanuelle Braud,Mélanie Ethève-Quelquejeu European Journal of Organic Chemistry, 2018, 2018 (32), pp.4411-4425. ⟨10.1002/ejoc.201800798⟩ Article dans une revue hal-02353523v1
Synthesis of lipid-carbohydrate-peptidyl-RNA conjugates to explore the limits imposed by the substrate specificity of cell wall enzymes on the acquisition of drug resistance Matthieu Fonvielle,Ahmed Bouhss,Coralie Hoareau,Delphine Patin,Dominique Mengin-Lecreulxet al. Chemistry - A European Journal, 2018, 24 (56), pp.14911-14915. ⟨10.1002/chem.201802360⟩ Article dans une revue hal-01962025v1
Synthesis of tRNA analogues containing a terminal ribose locked in the South conformation to study tRNA-dependent enzymes Laura Iannazzo,Matthieu Fonvielle,Emmanuelle Braud,Hubert Hřebabecký,Eliška Procházkováet al. Organic & Biomolecular Chemistry, 2018, 16 (11), pp.1903-1911. ⟨10.1039/C8OB00019K⟩ Article dans une revue hal-03689994v1
Is the 3,4-methylendioxypyrovalerone/mephedrone combination responsible for enhanced stimulant effects? A rat study with investigation of the effect/concentration relationships Nadia Benturquia,Lucie Chevillard,Christophe Poiré,Olivier Roussel,Camille Cohieret al. Psychopharmacology, 2018, ⟨10.1007/s00213-018-4962-0⟩ Article dans une revue hal-01899917v1
Synthesis of SAM-Adenosine Conjugates for the Study of m 6 A-RNA Methyltransferases Colette Atdjian,Laura Iannazzo,Emmanuelle Braud,Mélanie Ethève-Quelquejeu European Journal of Organic Chemistry, 2018, 2018 (32), pp.4411-4425. ⟨10.1002/ejoc.201800798⟩ Article dans une revue hal-03647207v1
Synthesis of SAM-Adenosine Conjugates for the Study of m 6 A-RNA Methyltransferases Colette Atdjian,Laura Iannazzo,Emmanuelle Braud,Mélanie Ethève-Quelquejeu European Journal of Organic Chemistry, 2018, 2018 (32), pp.4411-4425. ⟨10.1002/ejoc.201800798⟩ Article dans une revue hal-03689993v1
Critical Impact of Peptidoglycan Precursor Amidation on the Activity of l,d -Transpeptidases from Enterococcus faecium and Mycobacterium tuberculosis Flora Ngadjeua,Emmanuelle Braud,Saidbakhrom Saidjalolov,Laura Iannazzo,Dirk Schnappingeret al. Chemistry - A European Journal, 2018, 24 (22), pp.5743 - 5747. ⟨10.1002/chem.201706082⟩ Article dans une revue hal-01817697v1
Insights into the interaction of high potency inhibitor IRC-083864 with phosphatase CDC25 Manal Sarkis,Maria Miteva,Maria Chiara Dasso Lang,Maryse Jaouen,Marie-Agnès Sariet al. Proteins: Structure, Function, and Bioinformatics, 2017, 85 (4), pp.593-601. ⟨10.1002/prot.25236⟩ Article dans une revue hal-03684762v1
Insights into the interaction of high potency inhibitor IRC-083864 with phosphatase CDC25 Manal Sarkis,Maria Miteva,Maria Chiara Dasso Lang,Maryse Jaouen,Marie-Agnès Sariet al. Proteins: Structure, Function, and Bioinformatics, 2017, 85 (4), pp.593-601. ⟨10.1002/prot.25236⟩ Article dans une revue hal-03689998v1
Synthesis of Multifunctionalized 2-Iminothiazolidin-4-ones and Their 2-Arylimino Derivatives Laurent Le Corre,Maria Dasso Lang,Christiane Garbay,Christine Gravier-Pelletier,Patricia Buscaet al. Synthesis: Journal of Synthetic Organic Chemistry, 2016, 48 (24), pp.4569-4579. ⟨10.1055/s-0035-1562521⟩ Article dans une revue hal-05574025v1
Electrophilic RNA for Peptidyl-RNA Synthesis and Site-Specific Cross-Linking with tRNA-Binding Enzymes. Matthieu Fonvielle,Nicolas Sakkas,Laura Iannazzo,Chloé Le fournis,Delphine Patinet al. Angewandte Chemie International Edition, 2016, 55 (43), pp.13553-13557. ⟨10.1002/anie.201606843⟩ Article dans une revue istex hal-01440830v1
Monitoring of reversible boronic acid–diol interactions by fluorine NMR spectroscopy in aqueous media Laura Iannazzo,Erica Benedetti,Marjorie Catala,Mélanie Etheve-Quelquejeu,Carine Tisnéet al. Organic & Biomolecular Chemistry, 2015, 13 (33), pp.8817-8821. ⟨10.1039/c5ob01362c⟩ Article dans une revue hal-03544508v1
Kinetic features of L,D-transpeptidase inactivation critical for β-lactam antibacterial activity. Sébastien Triboulet,Vincent Dubée,Lauriane Lecoq,Catherine M Bougault,Jean-Luc Mainardiet al. PLoS ONE, 2013, 8 (7), pp.e67831. ⟨10.1371/journal.pone.0067831⟩ Article dans une revue hal-01321589v1
Fluoro-C-glycosides and fluoro-carbasugars, hydrolytically stable and synthetically challenging glycomimetics Eric Leclerc,Xavier Pannecoucke,Mélanie Etheve-Quelquejeu,M. Sollogoub Chemical Society Reviews, 2013, 42 (10), pp.4270-4283. ⟨10.1039/c2cs35403a⟩ Article dans une revue hal-00825637v1
Crystal structure of a chiral binaphthyl porphyrin Eric Rose,Nicolas Raoul,Mélanie Etheve-Quelquejeu,Emma Gallo,Bernard Boitrelet al. Journal of Porphyrins and Phthalocyanines, 2012, 16 (3), pp.324-330. ⟨10.1142/S1088424612500393⟩ Article dans une revue hal-00863134v1
Decoding the Logic of the tRNA Regiospecificity of Nonribosomal FemX Wv Aminoacyl Transferase Matthieu Fonvielle,Maryline Chemama,Maxime Lecerf,Régis Villet,Patricia Buscaet al. Angewandte Chemie International Edition, 2010, 49 (30), pp.5115-5119. ⟨10.1002/anie.201001473⟩ Article dans une revue hal-05573979v1
Idiosyncratic features in tRNAs participating in bacterial cell wall synthesis Régis Villet,Matthieu Fonvielle,Patricia Busca,Maryline Chemama,Antoine P. Maillardet al. Nucleic Acids Research, 2007, 35 (20), pp.6870-6883. ⟨10.1093/nar/gkm778⟩ Article dans une revue hal-02331010v1
Synthesis of 2′-O,3′-O bicyclic adenosine analogues using ring closing metathesis Patricia Busca,Mélanie Etheve-Quelquejeu,Jean-Marc Valéry Tetrahedron Letters, 2003, 44 (51), pp.9131-9134. ⟨10.1016/j.tetlet.2003.10.059⟩ Article dans une revue istex hal-05573999v1