Michael O'DONOHUE Directeur Scientifique du programme EXPLOR'AE (France 2030)Directeur del'infrastructure de recherche européenne IBISBA

Identifiants chercheurs

IdHAL :

michael-odonohue

ORCID :

0000-0003-4246-3938

IdRef :

076743535

ResearcherID :

http://www.researcherid.com/rid/E-9183-2013

Présentation

Michael O’Donohue travaille à l’INRAE, l'Institut national de recherche pour l'agriculture, l'alimentation et l'environnement. Il est titulaire d'un doctorat en biochimie des protéines de l'Université de Portsmouth (Royaume-Uni) et possède une vaste expérience de recherche en ingénierie enzymatique et en biotechnologie. De 2016 à 2024, Michael a dirigé la division TRANSFORM d’INRAE. Depuis janvier 2024, Michael est directeur scientifique d’EXPLOR’AE, un programme national qui finance la recherche à haut risque et à haute récompense. En 2014, Michael a lancé une initiative européenne visant à fédérer les capacités européennes et à développer une approche plus systémique de la recherche en biotechnologie et en biofabrication. Depuis, cette initiative est devenue IBISBA, une infrastructure de recherche européenne distribuée qui a obtenu la reconnaissance de l'ESFRI en 2018. IBISBA mobilise actuellement le personnel de 23 institutions de recherche situées dans 11 pays européens.

Publications

Article dans une revue (99)

Comparison of Machine Learning-Enhanced Dynamic Hybrid Models for a Nanobody Scorpion Antivenom Production with Escherichia Coli Irene Martínez-Menéndez,Juan Acosta-Pavas,David Camilo Corrales,Susana María Alonso Villela,Balkiss Bouhaouala-Zaharet al. Lecture Notes in Networks and Systems, 2025, Lecture Notes in Networks and Systems, 1259, pp.307-316. ⟨10.1007/978-3-031-82073-1_30⟩ Article dans une revue hal-05216714v1
Addressing semantic ambiguity in biotechnology: Proposals from the European research infrastructure IBISBA Marie Ancelin,Vitor a P Martins dos Santos,John P Morrissey,Michael J O'Donohue,Merja Penttiläet al. New Biotechnology, 2025, 88, pp.83 - 88. ⟨10.1016/j.nbt.2025.04.010⟩ Article dans une revue hal-05053127v1
A Soft Sensing Approach for Efficient Monitoring of Nanobody-Based Scorpion Antivenom Production Juan Acosta-Pavas,David Camilo Corrales,Irene Martínez-Menéndez,Susana María Alonso Villela,Balkiss Bouhaouala-Zaharet al. PLoS Pathogens, 2025, Lecture Notes in Networks and Systems, 1259 (4), pp.271-281. ⟨10.1007/978-3-031-82073-1_27⟩ Article dans une revue hal-05216632v1
Horizontal metaproteomics and CAZymes analysis of lignocellulolytic microbial consortia selectively enriched from cow rumen and termite gut Emeline Auer,Adèle Lazuka,Bertrand Huguenin-Bizot,Nico Jehmlich,Sébastien Déjeanet al. ISME Communications, 2024, 3 (1), pp.134. ⟨10.1038/s43705-023-00339-0⟩ Article dans une revue hal-04844011v1
Biotech potential set to soar with the help of digital technology Michael J O'Donohue Horizon Magazine, 2024, https://projects.research-and-innovation.ec.europa.eu/en/horizon-magazine/biotech-potential-set-soar-help-digital-technology#linkedin Article dans une revue hal-04727153v1
Synthesis of α-l-Araf and β-d-Galf series furanobiosides using mutants of a GH51 α-l-arabinofuranosidase Jiao Zhao,Jérémy Esque,Isabelle André,Michael O'Donohue,Régis Fauré Bioorganic Chemistry, 2021, 116, pp.105245. ⟨10.1016/j.bioorg.2021.105245⟩ Article dans une revue hal-03371339v1
Regioselective chemo-enzymatic syntheses of ferulate conjugates as chromogenic substrates for feruloyl esterases Olga Gherbovet,Fernando Ferreira,Apolline Clément,Mélanie Ragon,Julien Durandet al. Beilstein Journal of Organic Chemistry, 2021, 17, pp.325-333. ⟨10.3762/bxiv.2020.107.v1⟩ Article dans une revue hal-02988548v2
Multimodularity of a GH10 Xylanase Found in the Termite Gut Metagenome Haiyang Wu,Eleni Ioannou,Bernard Henrissat,Cédric Montanier,Sophie Bozonnetet al. Applied and Environmental Microbiology, 2021, 87 (3), ⟨10.1128/AEM.01714-20⟩ Article dans une revue hal-03146857v1
Rational enzyme design without structural knowledge: a sequence-based approach for efficient generation of transglycosylases David Teze,Jiao Zhao,Mathias Wiemann,Kazi Zubaida Gulshan Ara,Rossana Lupoet al. Chemistry - A European Journal, In press, ⟨10.1002/chem.202100110⟩ Article dans une revue hal-02906907v2
Waste-to-nutrition: a review of current and emerging conversion pathways U Javourez,Michael O'Donohue,Lorie Hamelin Biotechnology Advances, 2021, 53, 26 p. ⟨10.1016/j.biotechadv.2021.107857⟩ Article dans une revue hal-03426554v1
Probing the determinants of the transglycosylation/hydrolysis partition in a retaining α-l-arabinofuranosidase Jiao Zhao,Tobias Tandrup,Bastien Bissaro,Sophie Barbe,Jens-Christian Poulsenet al. New Biotechnology, 2021, 62, pp.68-78. ⟨10.1016/j.nbt.2021.01.008⟩ Article dans une revue hal-03139105v1
The Jo-In protein welding system is a relevant tool to create CBM-containing plant cell wall degrading enzymes Louise Badruna,Vincent Burlat,Pierre Roblin,Thomas Enjalbert,Guy Lippenset al. New Biotechnology, 2021, 65, pp.31-41. ⟨10.1016/j.nbt.2021.07.004⟩ Article dans une revue hal-03340154v1
Anaerobic lignocellulolytic microbial consortium derived from termite gut: enrichment, lignocellulose degradation and community dynamics Adèle Lazuka,Lucas Auer,Michael O'Donohue,Guillermina Hernandez Raquet Biotechnology for Biofuels, 2018, 11 (1), 14 p. ⟨10.1186/s13068-018-1282-x⟩ Article dans une revue hal-02621415v1
Biomasse : les enjeux pour l’avenir de la chimie du carbone Franck Dumeignil,Henri Strub,Hélène Olivier-Bourbigou,Jérôme François,Michael O'Donohueet al. L'Actualité Chimique, 2018, 427-428, pp.19-24 Article dans une revue hal-02906921v1
Developing cellulolytic Yarrowia lipolytica as a platform for the production of valuable products in consolidated bioprocessing of cellulose Zhongpeng Guo,Julien Robin,Sophie Duquesne,Michael O'Donohue,Alain Martyet al. Biotechnology for Biofuels, 2018, 11 (1), 15 p. ⟨10.1186/s13068-018-1144-6⟩ Article dans une revue hal-01886473v1
INRA's research in industrial biotechnology: For food, chemicals, materials and fuels Carole Camarasa,Hubert Chiron,Fayza Daboussi,Guy Della Valle,Claire Dumaset al. Innovative Food Science & Emerging Technologies / Innovative Food Science and Emerging Technologies , 2018, 46, pp.140-152. ⟨10.1016/j.ifset.2017.11.008⟩ Article dans une revue hal-03628058v1
Meeting new challenges in food science technology: the development of complex systems approach for food and biobased research Hugo de Vries,Monique Axelos,Pascale Manchado-Sarni,Michael O'Donohue Innovative Food Science & Emerging Technologies / Innovative Food Science and Emerging Technologies , 2018, 46, pp.1-6. ⟨10.1016/j.ifset.2018.04.004⟩ Article dans une revue hal-01837847v1
Analysis of large 16S rRNA Illumina datasets: impact of singleton read filtering on microbial community description Lucas Auer,Mahendra Mariadassou,Michael O'Donohue,Christophe Klopp,Guillermina Hernandez-Raquet Molecular Ecology Resources, 2017, ⟨10.1111/1755-0998.12700⟩ Article dans une revue (data paper) hal-01605865v1
Uncovering the potential of termite gut microbiome for lignocellulose bioconversion in anaerobic batch bioreactors Lucas Auer,Adèle Lazuka,David Sillam-Dussès,Edouard Miambi,Michael O'Donohueet al. Frontiers in Microbiology, 2017, 8, 14 p. ⟨10.3389/fmicb.2017.02623⟩ Article dans une revue hal-01886494v1
Conferring cellulose-degrading ability to Yarrowia lipolytica to facilitate a consolidated bioprocessing approach Zhongpeng Guo,Sophie Duquesne,Sophie Bozonnet,Gianluca Cioci,Jean-Marc Nicaudet al. Biotechnology for Biofuels, 2017, 10 (1), pp.13. ⟨10.1186/s13068-017-0819-8⟩ Article dans une revue hal-01605060v1
Ecofriendly lignocellulose pretreatment to enhance the carboxylate production of a rumen-derived microbial consortium Adèle Lazuka,Cécile Roland,Abdellatif Barakat,Fabienne Guillon,Michael O'Donohueet al. Bioresource Technology, 2017, 236, pp.225-233. ⟨10.1016/j.biortech.2017.03.083⟩ Article dans une revue hal-01607636v1
Expressing accessory proteins in cellulolytic Yarrowia lipolytica to improve the conversion yield of recalcitrant cellulose Zhongpeng Guo,Sophie Duquesne,Sophie Bozonnet,Jean-Marc Nicaud,Alain Martyet al. Biotechnology for Biofuels, 2017, 10 (1), 16 p. ⟨10.1186/s13068-017-0990-y⟩ Article dans une revue hal-01886440v1
Characterization and mutagenesis of two novel iron-sulphur cluster pentonate dehydratases Martina Andberg,Niina Aro-Karkkainen,Paul Carlson,Merja Oja,Sophie Bozonnetet al. Applied Microbiology and Biotechnology, 2016, 100 (17), pp.7549-7563. ⟨10.1007/s00253-016-7530-8⟩ Article dans une revue hal-01886409v1
Design of chromogenic probes for efficient screening and evaluation of feruloyl esterase-like activities Olga Gherbovet,Régis Fauré,Fernando Ferreira,Julien Durand,Mélanie Ragonet al. Journal of Molecular Catalysis B: Enzymatic, 2016, 126, pp.24-31. ⟨10.1016/j.molcatb.2016.01.012⟩ Article dans une revue istex hal-01450768v1
CAZyChip: dynamic assessment of exploration of glycoside hydrolases in microbial ecosystems Anne Abot,Grégory Arnal,Lucas Auer,Adèle Lazuka,Delphine Labourdetteet al. BMC Genomics, 2016, 17 (1), pp.1-12. ⟨10.1186/s12864-016-2988-4⟩ Article dans une revue hal-01843061v1
A single point mutation alters the transglycosylation/hydrolysis partition, significantly enhancing the synthetic capability of an endo-glycoceramidase Julien Durand,Xevi Biarnés,Laurie Watterlot,Cyrielle Bonzom,Vinciane Borsenbergeret al. ACS Catalysis, 2016, 6 (12), pp.8264-8275. ⟨10.1021/acscatal.6b02159⟩ Article dans une revue hal-01606355v1
The GH51 α-l-arabinofuranosidase from Paenibacillus sp. THS1 is multifunctional, hydrolyzing main-chain and side-chain glycosidic bonds in heteroxylans Hanen Bouraoui,Marie-Laure Desrousseaux,Eleni Ioannou,Pablo Alvira,Mohamed Manaïet al. Biotechnology for Biofuels, 2016, 9 (1), pp.1-14. ⟨10.1186/s13068-016-0550-x⟩ Article dans une revue hal-01595481v1
White biotechnology: state of the art strategies for the development of biocatalysts for biorefining Stephanie Heux,Isabelle Meynial Salles,Michael O'Donohue,Claire Dumon Biotechnology Advances, 2015, 33 (8), ⟨10.1016/j.biotechadv.2015.08.004⟩ Article dans une revue (article de synthèse) istex hal-01269233v1
Enhancing the chemoenzymatic synthesis of arabinosylated xylo-oligosaccharides by GH51 α-l-arabinofuranosidase Faten Arab-Jaziri,Bastien Bissaro,Charles Tellier,Michel Dion,Régis Fauréet al. Carbohydrate Research, 2015, 401, pp.64-72. ⟨10.1016/j.carres.2014.10.029⟩ Article dans une revue istex hal-02146151v1
Development of cellobiose-degrading ability in Yarrowia lipolytica strain by overexpression of endogenous genes Zhongpeng Guo,Sophie Duquesne,Sophie Bozonnet,Gianluca Cioci,Jean-Marc Nicaudet al. Biotechnology for Biofuels, 2015, 8, pp.1-16. ⟨10.1186/s13068-015-0289-9⟩ Article dans une revue hal-01185655v1
Glycosynthesis in a waterworld: new insight into the molecular basis of transglycosylation in retaining glycoside hydrolases Bastien Bissaro,Pierre Monsan,Régis Fauré,Michael j. O’donohue Biochemical Journal, 2015, 467 (1), pp.17-35. ⟨10.1042/BJ20141412⟩ Article dans une revue (article de synthèse) hal-02146118v1
Molecular design of non-Leloir furanose-transferring enzymes from an α-l-arabinofuranosidase: a rationale for the engineering of evolved transglycosylases Bastien Bissaro,Julien Durand,Xevi Biarnes,Antoni Planas,Pierre Monsanet al. ACS Catalysis, 2015, 5 (8), pp.4598-4611. ⟨10.1021/acscatal.5b00949⟩ Article dans une revue hal-01185302v1
Efficient anaerobic transformation of raw wheat straw by a robust cow rumen-derived microbial consortium Adèle Lazuka,Lucas Auer,Sophie Bozonnet,Diego Morgavi,Michael O'Donohueet al. Bioresource Technology, 2015, 196, pp.241-249. ⟨10.1016/j.biortech.2015.07.084⟩ Article dans une revue hal-01269314v1
Probing the functions of carbohydrate binding Modules in the CBEL protein from the oomycete Phytophthora parasitica Thomas Martinez,Hélène Texier,Virginie Nahoum,Claude Lafitte,Gianluca Ciociet al. PLoS ONE, 2015, 10 (9), ⟨10.1371/journal.pone.0137481⟩ Article dans une revue hal-02635206v1
Investigating the function of an arabinan utilization locus isolated from a termite gut community Grégory Arnal,Geraldine Bastien-Uluis,Nelly Monties,Anne Abot,Véronique Le Berreet al. Applied and Environmental Microbiology, 2015, 81 (1), pp.31-9. ⟨10.1128/AEM.02257-14⟩ Article dans une revue hal-01269098v1
Biorefineries for food, fuels and materials Rene Wijffels,Johan Sanders,Ton van Boxtel,Michael O'Donohue Biofuels, Bioproducts & Biorefining, 2014, 8 (4), pp.453 - 455. ⟨10.1002/bbb.1508⟩ Article dans une revue istex hal-01268869v1
First Structural Insights into α-l-Arabinofuranosidases from the Two GH62 Glycoside Hydrolase Subfamilies Béatrice Siguier,Mireille Haon,Virginie Nahoum,Marlène Marcellin,Odile Burlet-Schiltzet al. Journal of Biological Chemistry, 2014, 289 (8), pp.5261-5273. ⟨10.1074/jbc.M113.528133⟩ Article dans une revue hal-02419708v1
Mutation of a pH-modulating residue in a GH51 α-l-arabinofuranosidase leads to a severe reduction of the secondary hydrolysis of transfuranosylation products Bastien Bissaro,Olivier Saurel,Faten Arab-Jaziri,Luc Saulnier,Alain Milonet al. Biochimica et Biophysica Acta (BBA) - General Subjects, 2014, 1840 (1), pp.626-636. ⟨10.1016/j.bbagen.2013.10.013⟩ Article dans une revue istex hal-02146185v1
A 1H NMR study of the specificity of α-l-arabinofuranosidases on natural and unnatural substrates Vinciane Borsenberger,Emmie Dornez,Marie-Laure Desrousseaux,Stéphane Massou,Maija Tenkanenet al. Biochimica et Biophysica Acta (BBA) - General Subjects, 2014, 1840 (10), pp.3106-3114. ⟨10.1016/j.bbagen.2014.07.001⟩ Article dans une revue istex hal-02146175v1
Impact of an N-terminal extension on the stability and activity of the GH11 xylanase from Thermobacillus xylanilyticus Letian Song,Claire Dumon,Béatrice Siguier,Isabelle André,Elena Eneyskayaet al. Journal of Biotechnology, 2014, 174, pp.64-72. ⟨10.1016/j.jbiotec.2014.01.004⟩ Article dans une revue istex hal-01268735v1
Combined approaches provide an anatomical and transcriptomic fingerprint of maize cell wall digestibility Mary Sarah-Jane Wong Quai M. S.-J. W. Q. Lam,Yves Martinez,Odile Barbier,Alain Jauneau,Sandrine Balzergueet al. Maydica, 2013, 58 (1-4), pp.274 - 287 Article dans une revue hal-01195495v1
Engineering transglycosidase activity into a GH51 α-l-arabinofuranosidase Faten Arab-Jaziri,Bastien Bissaro,Michel Dion,Olivier Saurel,David Harrisonet al. New Biotechnology, 2013, 30 (5), pp.536-544. ⟨10.1016/j.nbt.2013.04.002⟩ Article dans une revue istex hal-02146240v1
Paenibacillus marinum sp nov., a thermophilic xylanolytic bacterium isolated from a marine hot spring in Tunisia Hanene Bouraoui,Hanen Rebib,Melek Ben Aissa,Jean-Pierre Touzel,Michael O'Donohueet al. Journal of Basic Microbiology, 2013, 53 (11), pp.877 - 883. ⟨10.1002/jobm.201200275⟩ Article dans une revue istex hal-01268471v1
Mining for hemicellulases in the fungus-growing termite Pseudacanthotermes militaris using functional metagenomics Geraldine Bastien-Uluis,Grégory Arnal,Sophie Bozonnet,Sandrine Laguerre-Gheusi,Fernando Ferreiraet al. Biotechnology for Biofuels, 2013, 6, online (may), Non paginé. ⟨10.1186/1754-6834-6-78⟩ Article dans une revue hal-01268110v1
Comparison of the Heterologous Expression of Trichoderma reesei Endoglucanase II and Cellobiohydrolase II in the Yeasts Pichia pastoris and Yarrowia lipolytica Nassapat Boonvitthya,Sophie Bozonnet,Vorakan Burapatana,Michael O'Donohue,Warawut Chulalaksananukul Molecular Biotechnology, 2013, 54 (2), pp.158 - 169. ⟨10.1007/s12033-012-9557-0⟩ Article dans une revue istex hal-01268106v1
La biomasse, simple source d'énergie ou source de matières premières renouvelables ? Michael O'Donohue Innovations Agronomiques, 2013, 26, pp.41-50. ⟨10.17180/dfj4-d146⟩ Article dans une revue hal-01268036v1
A substrate for the detection of broad specificity alpha-L-arabinofuranosidases with indirect release of a chromogenic group Vinciane Borsenberger,Emmie Dornez,Marie-Laure Desrousseaux,Christophe M. Courtin,Michael O'Donohueet al. Tetrahedron Letters, 2013, 54 (24), pp.3063 - 3066. ⟨10.1016/j.tetlet.2013.03.136⟩ Article dans une revue istex hal-01268100v1
Redefining XynA from Penicillium funiculosum IMI 378536 as a GH7 cellobiohydrolase Hélène Texier,Claire Dumon,Virginie Neugnot-Roux,Marc Maestracci,Michael O'Donohue Journal of Industrial Microbiology and Biotechnology, 2012, 39 (11), pp.1569 - 1576. ⟨10.1007/s10295-012-1166-1⟩ Article dans une revue istex hal-01268269v1
Engineering better biomass-degrading ability into a GH11 xylanase using a directed evolution strategy Letian Song,Béatrice Siguier,Claire Dumon,Sophie Bozonnet,Michael O'Donohue Biotechnology for Biofuels, 2012, 5, ⟨10.1186/1754-6834-5-3⟩ Article dans une revue hal-01268365v1
Progress and future prospects for pentose-specific biocatalysts in biorefining Claire Dumon,Letian Song,Sophie Bozonnet,Régis Fauré,Michael O'Donohue Process Biochemistry, 2012, 47 (3), pp.346 - 357. ⟨10.1016/j.procbio.2011.06.017⟩ Article dans une revue istex hal-01268406v1
Characterization of Deinococcus sahariens sp nov., a radiation-resistant bacterium isolated from a Saharan hot spring Hanene Bouraoui,Melek Ben Aissa,Feten Abbassi,Jean-Pierre Touzel,Michael O'Donohueet al. Archives of Microbiology, 2012, 194 (5), pp.315 - 322. ⟨10.1007/s00203-011-0762-1⟩ Article dans une revue istex hal-01268345v1
Thumb-loops up for catalysis: a structure/function investigation of a functional loop movement in a GH11 xylanase Gabriel Paës,Juan Cortés,Thierry Simeon,Michael O'Donohue,Vinh Tran Computational and Structural Biotechnology Journal, 2012, 1 (2), pp.e201207001. ⟨10.5936/csbj.201207001⟩ Article dans une revue hal-01267831v1
Biomass-derived pentoses Michael O'Donohue,Bärbel Hahn-Hägerdal Process Biochemistry, 2012, 47 (3), pp.345. ⟨10.1016/j.procbio.2011.10.021⟩ Article dans une revue istex hal-01268458v1
Functional roles of H98 and W99 and beta 2 alpha 2 loop dynamics in the alpha-L-arabinofuranosidase from Thermobacillus xylanilyticus Faten Arab,Bastien Bissaro,Sophie Barbe,Olivier Saurel,Helene Debatet al. FEBS Journal, 2012, 279 (19), pp.3598 - 3611. ⟨10.1111/j.1742-4658.2012.08720.x⟩ Article dans une revue hal-01268289v1
Effect of lignin content on a GH11 endoxylanase acting on glucuronoarabinoxylan-lignin nanocomposites Imen Boukari,Michael O'Donohue,Caroline Rémond,Brigitte Chabbert Carbohydrate Polymers, 2012, 89, pp.423-431. ⟨10.1016/j.carbpol.2012.03.024⟩ Article dans une revue istex hal-02645858v1
A Versatile and Colorful Screening Tool for the Identification of Arabinofuranose-Acting Enzymes Vinciane Borsenberger,Fernando Ferreira,Annick Pollet,Emmie Dornez,Marie-Laure Desrousseauxet al. ChemBioChem, 2012, 13 (13), pp.1885 - 1888. ⟨10.1002/cbic.201200394⟩ Article dans une revue istex hal-01268282v1
Probing a family GH11 endo-beta-1,4-xylanase inhibition mechanism by phenolic compounds: Role of functional phenolic groups Imen Boukari,Michael O Donohue,Caroline Rémond,Brigitte Chabbert Journal of Molecular Catalysis B: Enzymatic, 2011, 72 (3-4), pp.130-138. ⟨10.1016/j.molcatb.2011.05.010⟩ Article dans une revue istex hal-02649536v1
Des déchets agricoles pour produire carburants et plastiques verts Pierre Le Hir,Michael O'Donohue,Michel Delmas,Yvonne Goncalves Le Monde, 2011 Article dans une revue hal-02644127v1
A high-throughput screening system for the evaluation of biomass-hydrolyzing glycoside hydrolases Letian Song,S. Laguerre,C. Dumon,Sophie Bozonnet,Michael O'Donohue Bioresource Technology, 2010, 101 (21), pp.8237 - 8243. ⟨10.1016/j.biortech.2010.05.097⟩ Article dans une revue istex hal-02659454v1
Caldimonas hydrothermale sp. nov., a novel thermophilic bacterium isolated from Roman hot bath in south Tunisia Hanene Bouraoui,Imen Boukari,Jean-Pierre Touzel,Michael O'Donohue,Mohamed Manaï Archives of Microbiology, 2010, 192 (6), pp.485-91. ⟨10.1007/s00203-010-0576-6⟩ Article dans une revue istex hal-02658825v1
A brief and informationally rich naming system for oligosaccharide motifs of heteroxylans found in plant cell walls R. Faure,C.M. Courtin,J.A. Delcour,C. Dumon,C.B. Fauldset al. Australian Journal of Chemistry, 2009, 62, pp.533-537. ⟨10.1071/CH08458⟩ Article dans une revue hal-00396624v2
In vitro model assemblies to study the impact of lignin-carbohydrate interactions on the enzymatic conversion of Xylan Imen Boukari,Jean-Luc Putaux,Bernard Cathala,Abdellatif Barakat,Bodo Saakeet al. Biomacromolecules, 2009, 10 (9), pp.2489-2498. ⟨10.1021/bm9004518⟩ Article dans une revue hal-02666812v1
Evaluation of the transglycosylation activities of a GH 39 beta-D-xylosidase for the synthesis of xylose-based glycosides M. Muzard,Nathalie Aubry,R. Plantier-Royon,Michael O Donohue,Caroline Rémond Journal of Molecular Catalysis B: Enzymatic, 2009, 58 (1-4), pp.1-5. ⟨10.1016/j.molcatb.2008.10.004⟩ Article dans une revue istex hal-02667032v1
Biocatalytic conversion of wheat bran hydrolysate using an immobilized GH43 beta-xylosidase Issam Smaali,Caroline Rémond,Yousr Skhiri,Michael O Donohue Bioresource Technology, 2009, 100 (1), pp.338-344. ⟨10.1016/j.biortech.2008.06.041⟩ Article dans une revue istex hal-02663118v1
La production de carburants à partir de biomasse lignocellulosique par voie biologique : état de l’art et perspectives Michael O'Donohue Oléagineux, Corps Gras, Lipides, 2008, 15 (3), pp.172-177. ⟨10.1051/ocl.2008.0190⟩ Article dans une revue hal-02908301v1
The complex between a branched pentasaccharide and Thermobacillus xylanilyticus arabinofuranosidase M. Gajhede,G. Paes,Michael O'Donohue,L.K. Skov,J.S. Kastrupet al. Acta Crystallographica Section A : Foundations of Crystallography [1968-2013], 2008, 64 (a1), pp.C283-C283. ⟨10.1107/S0108767308090946⟩ Article dans une revue hal-03146868v1
Action of a GH51 alpha-L-arabinofuranosidase on wheat derived arabinoxylans and arabino-xylooligosaccharides. Caroline Rémond,Imen Boukari,G. Chambat,Michael O Donohue Carbohydrate Polymers, 2008, 72 (3), pp.424-430. ⟨10.1016/j.carbpol.2007.09.008⟩ Article dans une revue istex hal-02663477v1
The Structure of the Complex between a Branched Pentasaccharide and Thermobacillus xylanilyticus GH-51 Arabinofuranosidase Reveals Xylan-Binding Determinants and Induced Fit Gabriel Paës,Lars Skov,Michael O Donohue,Caroline Rémond,Jette Kastrupet al. Biochemistry, 2008, 47 (28), pp.7441-7451. ⟨10.1021/bi800424e⟩ Article dans une revue istex hal-02668354v1
New chromogenic substrates for feruloyl esterases Laurence Marmuse,Michèle Asther,Emeline Fabre,David Navarro,Laurence Lesage-Meessenet al. Organic & Biomolecular Chemistry, 2008, 6 (7), pp.1208. ⟨10.1039/b717742a⟩ Article dans une revue istex hal-02655815v1
Investigation of the specificity of an alpha-L-arabinofuranosidase using C-2 and C-5 modified alpha-L-arabinofuranosides Gérald Lopez,Caroline Nugier-Chauvin,Caroline Rémond,Michael O Donohue Carbohydrate Research, 2007, 342 (15), pp.2202-2211. ⟨10.1016/j.carres.2007.06.001⟩ Article dans une revue istex hal-02659822v1
New insights into the role of the thumb-like loop in GH-11 xylanases Gabriel Paës,Vinh Tran,Masayuki Takahashi,Imen Boukari,Michael O Donohue Protein Engineering, Design and Selection, 2007, 20 (1), pp.15-23. ⟨10.1093/protein/gzl049⟩ Article dans une revue hal-02659467v1
Adaptation des procédés, biotechnologies blanches Michael O'Donohue,Pierre Monsan Biofutur, 2007 Article dans une revue hal-02908307v1
Thioimidoyl furanosides as first inhibitors of the α-l-arabinofuranosidase AbfD3 Gérald Lopez,Richard Daniellou,Michael O'Donohue,Vincent Ferrières,Caroline Nugier-Chauvin Bioorganic and Medicinal Chemistry Letters, 2007, 17 (2), pp.434-438. ⟨10.1016/j.bmcl.2006.10.032⟩ Article dans une revue istex hal-00405292v1
Expression in Escherichia coli and characterization of beta-xylosidases GH-39 and GH-43 from Bacillus halodurans C-125 Issam Smaali,Caroline Rémond,Michael O Donohue Applied Microbiology and Biotechnology, 2006, 73 (3), pp.582-590. ⟨10.1007/s00253-006-0512-5⟩ Article dans une revue istex hal-02660151v1
Engineering increased thermostability in the thermostable GH-11 xylanase from Thermobacillus xylanilyticus Gabriel Paës,Michael O Donohue Journal of Biotechnology, 2006, 125 (3), pp.338-350. ⟨10.1016/j.jbiotec.2006.03.025⟩ Article dans une revue istex hal-02660155v1
A chemoenzymatic approach for the synthesis of unnatural dissacharides containing D-galacto- or D-fucofuranosides Ronan Euzen,Gérald Lopez,Caroline Nugier-Chauvin,Vincent Ferrières,Daniel Plusquellecet al. Global Change Biology, 2005, 2005 (22), pp.4860-4869. ⟨10.1002/ejoc.200500525⟩ Article dans une revue hal-02682640v1
An original chemoenzymatic route for the synthesis of β-D-galactofuranosides using an α-L-arabinofuranosidase Caroline Rémond,Richard Plantier-Royon,Nathalie Aubry,Michael O Donohue Carbohydrate Research, 2005, 340 (4), pp.637-644. ⟨10.1016/j.carres.2005.01.016⟩ Article dans une revue istex hal-02678181v1
Probing the cell-wall heterogeneity of micro-dissected wheat caryopsis using well-characterized active and non-active GH11 xylanases Johnny Beaugrand,Gabriel Paës,Danièle Reis,Masayuki Takahashi,Philippe Debeireet al. Planta, 2005, 222 (2), pp.246-257. ⟨10.1007/s00425-005-1538-0⟩ Article dans une revue istex hal-02675507v1
Bioinformatics of the family 57 glycoside hydrolases and identification of catalytic residues in amylopullulanase from Thermococcus hydrothermalis Richard Zona,Florent Chang-Pi-Hin,Michael O Donohue,Stefan Janecek European Journal of Biochemistry, 2004, 271 (14), pp.2863-2872. ⟨10.1111/j.1432-1033.2004.04144.x⟩ Article dans une revue hal-02683580v1
Impact and efficiency of GH10 and GH11 thermostable endoxylanases on wheat bran and alkali-extractable arabinoxylans Johnny Beaugrand,Gérard Chambat,Vicky W.K. Wong,Florence Goubet,Caroline Rémondet al. Carbohydrate Research, 2004, 339 (15), pp.2529-2540. ⟨10.1016/j.carres.2004.08.012⟩ Article dans une revue istex hal-02681326v1
Synthesis of pentose-containing disaccharides using a thermostable α-l-arabinofuranosidase Caroline Rémond,Richard Plantier-Royon,Nathalie Aubry,Emmanuel Maes,Christophe C. Bliardet al. Carbohydrate Research, 2004, 339 (11), pp.2019-2025. ⟨10.1016/j.carres.2004.04.017⟩ Article dans une revue istex hal-02073657v1
A versatile assay for the accurate, time-resolved determination of cellular viability Toyoki Amano,Ken-Ichi Hirasawa,Michael O'Donohue,J Claude Pernollet,Yuzo Shioi Analytical Biochemistry, 2003, 314 (1), pp.1-7 Article dans une revue hal-02672643v1
Probing the catalytically essential residues of the α-l-arabinofuranosidase from Thermobacillus xylanilyticus Takoua Debeche,Christophe C. Bliard,Philippe Debeire,Michael O'Donohue Protein Engineering, Design and Selection, 2002, 15 (1), pp.21-28. ⟨10.1093/protein/15.1.21⟩ Article dans une revue hal-02074537v1
Chemoenzymatic syntheses of linear and branched hemithio-maltodextrins as potential inhibitors for starch debranching enzymes L. Greffe,M.T. Jensen,F. Chang-Pi-Hin,S. Fruchard,M.J. O'Donohueet al. Chemistry - A European Journal, 2002, pp.5447-5455 Article dans une revue hal-00307306v1
Thermobacillus xylanilyticus gen. nov., sp. nov., a new aerobic thermophilic xylan-degrading bacterium isolated from farm soil J.P. Touzel,Michael O'Donohue,Philippe Debeire,E. Samain,C. Breton International Journal of Systematic and Evolutionary Microbiology, 2000, 50, pp.315-320 Article dans une revue hal-02696650v1
Genetic and Biochemical Characterization of a Highly Thermostable α-l-Arabinofuranosidase fromThermobacillus xylanilyticus Takoua Debeche,Nicola Cummings,Ian Connerton,Philippe Debeire,Michael O'Donohue Applied and Environmental Microbiology, 2000, 66 (4), pp.1734-1736. ⟨10.1128/AEM.66.4.1734-1736.2000⟩ Article dans une revue hal-02908292v1
The type II pullulanase of Thermococcus hydrothermalis : Molecular characterization of the gene and expression of the catalytic domain M. Erra-Pujada,Philippe Debeire,Francis Duchiron,Michael O'Donohue Journal of Bacteriology, 1999, 181 (10), pp.3284-3287 Article dans une revue hal-02697820v1
The 2.1 A structure of an elicitin-ergosterol complex: a recent addition to the sterol carrier protein family G. Boissy,Michael O'Donohue,O. Gaudemer,V. Perez,J.C. Pernolletet al. Protein Science, 1999, 8, pp.1191-1199 Article dans une revue hal-02695917v1
A novel elicitin necrotic site revealed by alpha-cinnamomin sequence and site-directed mutagenesis V. Perez,J.C. Huet,Michael O'Donohue,Claude Nespoulous,J.C. Pernollet Phytochemistry, 1999, 50 (6), pp.961-966 Article dans une revue hal-02689192v1
Phytophthora resistance through production of a fungal protein elicitor (beta-cryptogein) in tobacco David Tepfer,C. Boutteaux,C. Vigon,S. Aymes,V. Perezet al. Molecular Plant-Microbe Interactions, 1998, 11 (1), pp.64-67 Article dans une revue hal-02689195v1
Evidence by site-directed mutagenesis that arginine 203 of thermolysin and arginine 717 of neprilysin (neutral endopeptidase) play equivalent critical roles in substrate hydrolysis and inhibitor binding. Cynthia Marie-Claire,Emmanuel Ruffet,Serge Antonczak,Ann Beaumont,Michael O'Donohueet al. Biochemistry, 1997, 36 (45), pp.13938-45. ⟨10.1021/bi9712495⟩ Article dans une revue istex inserm-00171023v1
Overexpression in Pichia pastoris and Crystallization of an Elicitor Protein Secreted by the Phytopathogenic Fungus, Phytophthora cryptogea Michael O'Donohue,Guillaume Boissy,Jean-Claude Huet,Claude Nespoulous,Simone Brunieet al. Protein Expression and Purification, 1996, 8 (2), pp.254-261. ⟨10.1006/prep.1996.0098⟩ Article dans une revue istex hal-02906918v1
The roles of the prosequence of thermolysin in enzyme inhibition and folding in vitro Michael O'Donohue,Ann Beaumont Journal of Biological Chemistry, 1996, 271 (43), pp.26477-26481. ⟨10.1074/jbc.271.43.26477⟩ Article dans une revue hal-02695052v1
A method for introducing site-specific mutations using oligonucleotide primers and its application to site-saturation mutagenesis M.J. O'Donohue,G.G. Kneale Molecular Biotechnology, 1996, 6, pp.179-189 Article dans une revue hal-02691266v1
The role of histidine 231 in thermolysin-like enzymes Ann Beaumont,Michael O'Donohue,Nathalie Paredes,Nathalie Rousselet,Marcel Assicotet al. Journal of Biological Chemistry, 1995, 270 (28), pp.16803-16808. ⟨10.1074/jbc.270.28.16803⟩ Article dans une revue hal-02711870v1
Chemical synthesis, expression and mutagenesis of a gene encoding B-cryptogein, an elicitin produced by Phytophthora cryptogea M.J. O'Donohue,H. Gousseau,J.C. Huet,David Tepfer,J.C. Pernollet Plant Molecular Biology, 1995, 27 (3), pp.577-586. ⟨10.1007/BF00019323⟩ Article dans une revue istex hal-02700301v1
Cloning and expression in Bacillus subtilis of the npr gene from Bacillus thermoproteolyticus Rokko coding for the thermostable metalloprotease thermolysin Michael O'Donohue,B. Roques,A. Beaumont Biochemical Journal, 1994, 300 (2), pp.599-603. ⟨10.1042/bj3000599⟩ Article dans une revue hal-02906914v1
Identification and Characterization of Various Cholecystokinin B Receptor mRNA Forms in Rat Brain Tissue and Partial Determination of the Cholecystokinin B Receptor Gene Structure A. Jagerschmidt,T. Popovici,Michael O'Donohue,B. Roques Journal of Neurochemistry, 1994, 63 (4), pp.1199-1206. ⟨10.1046/j.1471-4159.1994.63041199.x⟩ Article dans une revue hal-02906916v1
Tyr26 and Phe73 are essential for full biological activity of the Fd Gene 5 protein M.J. O'Donohue,G.P. Scarlett,G.G. Kneale FEMS Microbiology Letters, 1993, 109 (2-3), pp.219-223. ⟨10.1111/j.1574-6968.1993.tb06171.x⟩ Article dans une revue hal-02906915v1

Chapitre d'ouvrage (6)

Dynamic Hybrid Model for Nanobody-based Antivenom Production (scorpion antivenon) with E. coli CH10-12 and E. coli NbF12-10 David Camilo Corrales Munoz,Susana María Alonso Villela,Balkiss Bouhaouala-Zahar,Julien Cescut,Fayza Daboussiet al. Flavio Manenti, G.V. Rex Reklaitis. 34th European Symposium on Computer Aided Process Engineering / 15th International Symposium on Process Systems Engineering, 53, Elsevier, pp.145-150, 2024, Computer Aided Chemical Engineering, eBook ISBN: 9780443288258. ⟨10.1016/B978-0-443-28824-1.50025-9⟩ Chapitre d'ouvrage hal-04642732v1
Le biosourcé va-t-il verdir le bâtiment Michael O'Donohue,Monique Axelos,Sarah-Louise Filleux,Chavance Yann,Lerayer Pierre-Yveset al. "Ressources" n°3, la revue INRAE, 3, pp.66-85, 2023, ⟨10.17180/T5CZ-WM26⟩ Chapitre d'ouvrage hal-03959362v1
Les biotechnologies industrielles : plaque tournante à la croisée des IAA et de la chimie verte Cédric Montanier,Michael O'Donohue Chimie verte et industries agroalimentaires - Vers une bioéconomie durable, 2020 Chapitre d'ouvrage hal-02889114v1
Industrial biotechnology in the food and feed sector Michael O'Donohue,Pierre Monsan Industrial biotechnology : sustainable growth and economic success, Wiley-VCH, 522 p., 2010, 978-3-527-31442-3 Chapitre d'ouvrage hal-02820702v1
Fractionnement de la biomasse lignocellulosique : production de produits chimiques de bases Michael O'Donohue,Philippe Debeire La chimie verte, 2006 Chapitre d'ouvrage hal-02908325v1
Primer-directed site-specific mutagenesis Michael O'Donohue,G. Geoff Geoff Kneale The nucleic acid protocols handbook, 2000 Chapitre d'ouvrage hal-02908333v1

Brevet (3)

MUTANT YEAST STRAIN CAPABLE OF DEGRADING CELLULOSE Zhongpeng Guo,Alain Marty,Michael O'Donohue,Sophie Bozonnet,Sophie Duquesneet al. France, Patent n° : EP17155699. 2017 Brevet hal-02961883v1
Mutant yeast strain capable of degrading cellobiose Alain Marty,Zhongpeng Guo,Sophie Duquesne,Sophie Bozonnet,Jean Marc Nicaudet al. France, Patent n° : EP3085788A1. https://hal.inrae.fr/view/index/identifiant/hal-01603591. 2016 Brevet hal-02958258v1
Hemicellulose-degrading compositions and uses thereof Michael O'Donohue,Pablo Alvira,Claire Dumon France, Patent n° : WO2016135173 (A1). 2016 Brevet hal-01603913v1

Autre publication scientifique (5)

2021 IBISBA report: current status Michael O'Donohue 2021, ⟨10.34701/ibisba.1.document.34.1⟩ Autre publication scientifique hal-03309034v1
Recherches et Innovations pour l'Aliment et les Bioproduits Michael O'Donohue,Mélanie Delclos,Laurence Prevosto,. Département Cepia 2017, 44 p. ⟨10.15454/1.508483782951509E12⟩ Autre publication scientifique hal-01886427v1
Meeting the challenges of industrial biotechnology in the age of synthetic biology Michael O'Donohue 2015, 11 p. ⟨10.15454/1.495001900830255E12⟩ Autre publication scientifique hal-01603492v1
Technical note on pentose sugars and their applications Michael O'Donohue 2013, pp.4 Autre publication scientifique hal-01268773v1
Technical note on lignins and their applications Michael O'Donohue 2012, pp.4 Autre publication scientifique hal-01268774v1